Currently there are no medications approved for the treatment of methamphetamine addiction. Bupropion is an antidepressant that is approved by the Food and Drug Administration (FDA) for the treatment of depression and for cigarette smoking cessation but is not approved by the FDA for the treatment of methamphetamine addiction. Preliminary research studies suggest that bupropion may help people receiving treatment for methamphetamine addiction to reduce or to stop their methamphetamine use. But results of these studies also suggest that bupropion may help certain groups of patients more than others, such as men versus women and light versus heavy methamphetamine users, although the reasons for this difference are not known. One possibility is that a persons genetic make up may influence whether or not they respond to treatment with bupropion for methamphetamine addiction.. The purpose of the study is to determine if bupropion is can help people reduce or stop their methamphetamine use and to ...
(Prenatal Methamphetamine Exposure) Although research on the medical and developmental effects of prenatal methamphetamine exposure is still in its early stages, our experience with almost 20 years of research on the chemically related drug, cocaine, has not identified a recognizable condition, syndrome or disorder that should be termed crack baby nor found the degree of
TY - JOUR. T1 - Effects of chronic methamphetamine exposure on heart function in uninfected and retrovirus-infected mice. AU - Yu, Qianli. AU - Montes, Sergio. AU - Larson, Douglas F. AU - Watson, Ronald R. PY - 2002/7/12. Y1 - 2002/7/12. N2 - Methamphetamine (MA) increases catecholamine levels, which have detrimental effects on heart function through vasoconstriction, myocardial hypertrophy, and fibrosis. Murine retrovirus infection induces dilated cardiomyopathy (DCM). The present study investigated the cardiovascular effects of chronic MA treatment on uninfected and retrovirus-infected mice. C57BL/6 mice were studied after 12 weeks treatment. The four study groups were (group I) uninfected, MA placebo; (group II) infected, MA placebo; (group III) uninfected, MA treatment; and (group IV) infected and MA treatment. MA injections were given i.p. once a day for 5 days/week with a increasing dose from 15 mg/kg to 40 mg/kg. Left ventricular mechanics were measured in situ a using Millar conductance ...
TY - JOUR. T1 - The role of system Xc− in methamphetamine-induced dopaminergic neurotoxicity in mice. AU - Dang, Duy Khanh. AU - Shin, Eun Joo. AU - Tran, Hai Quyen. AU - Kim, Dae Joong. AU - Jeong, Ji Hoon. AU - Jang, Choon Gon. AU - Nah, Seung Yeol. AU - Sato, Hideyo. AU - Nabeshima, Toshitaka. AU - Yoneda, Yukio. AU - Kim, Hyoung Chun. PY - 2017/9. Y1 - 2017/9. N2 - The cystine/glutamate antiporter (system Xc−, Sxc) transports cystine into cell in exchange for glutamate. Since xCT is a specific subunit of Sxc, we employed xCT knockout mice and investigated whether this antiporter affected methamphetamine (MA)-induced dopaminergic neurotoxicity. MA treatment significantly increased striatal oxidative burdens in wild type mice. xCT inhibitor [i.e., S-4-carboxy-phenylglycine (CPG), sulfasalazine] or an xCT knockout significantly protected against these oxidative burdens. MA-induced increases in Iba-1 expression and Iba-1-labeled microglial immunoreactivity (Iba-1-IR) were significantly ...
TY - JOUR. T1 - Higher cortical and lower subcortical metabolism in detoxified methamphetamine abusers. AU - Volkow, N. D.. AU - Chang, L.. AU - Wang, G. J.. AU - Fowler, J. S.. AU - Franceschi, D.. AU - Sedler, M. J.. AU - Gatley, S. J.. AU - Hitzemann, R.. AU - Ding, Y. S.. AU - Wong, C.. AU - Logan, J.. PY - 2001/3/21. Y1 - 2001/3/21. N2 - Objective: Methamphetamine has raised concerns because it may be neurotoxic to the human brain. Although prior work has focused primarily on the effects of methamphetamine on dopamine cells, there is evidence that other neuronal types are affected. The authors measured regional brain glucose metabolism, which serves as a marker of brain function, to assess if there is evidence of functional changes in methamphetamine abusers in regions other than those innervated by dopamine cells. Method: Fifteen detoxified methamphetamine abusers and 21 comparison subjects underwent positron emission tomography following administration of [18F]fluorodeoxyglucose. Results: ...
Prenatal methamphetamine exposure (PME) is the exposure of a fetus to methamphetamine when a woman uses the drug during her pregnancy. Methamphetamine (MA) has shown increasing popularity in the past two decades among women of childbearing age. Methamphetamine is second only to cannabis as the most widely used illegal drug, which may be because it is relatively cheap and easy to manufacture. Yet, to this date, the effects of PME on the developing fetus have not been well characterized and even less is known regarding the effects on development in childhood. Although few studies have established a pattern of MA use in pregnant users, it is important that researchers seek to determine this pattern to examine a possible dose-response relationship between MA use and neonatal outcomes. The recent increase in MA use in the United States, particularly in the South and Midwest, highlights the need for a better understanding of the short-term and long-term effects of MA use during pregnancy upon newborns ...
Memory is a complex of systems by which an organism registers, stores and retrieves exposure to an event or experience. Literature purports that methamphetamine users and dependents have been found to exhibits signs of memory impairment. The aim of the research was to establish the possible existence of significant differences in memory in current methamphetamine users, recovering methamphetamine users, and a matched drug naïve control group. Cognitive functioning was assessed via a neurocognitive test battery that examined the memory of 14 current methamphetamine users, 17 recovering methamphetamine addicts, and 18 drug naïve control participants who were matched according to the demographic variables of age, gender and educational status. The results indicated that recovering methamphetamine users experienced the greatest impairment in memory in comparison to both the control group and current users of methamphetamine. The current users of methamphetamine also experienced some impairment in memory
TY - JOUR. T1 - Methamphetamine self-administration causes persistent striatal dopaminergic alterations and mitigates the deficits caused by a subsequent methamphetamine exposure. AU - McFadden, Lisa M.. AU - Hadlock, Greg C.. AU - Allen, Scott C.. AU - Vieira-Brock, Paula L.. AU - Stout, Kristen A.. AU - Ellis, Jonathan D.. AU - Hoonakker, Amanda J.. AU - Andrenyak, David M.. AU - Nielsen, Shannon M.. AU - Wilkins, Diana G.. AU - Hanson, Glen R.. AU - Fleckenstein, Annette E.. PY - 2012/2/1. Y1 - 2012/2/1. N2 - Preclinical studies have demonstrated that repeated methamphetamine (METH) injections (referred to herein as a "binge" treatment) cause persistent dopaminergic deficits. A few studies have also examined the persistent neurochemical impact of METH self-administration in rats, but with variable results. These latter studies are important because: 1) they have relevance to the study of METH abuse; and 2) the effects of noncontingent METH treatment do not necessarily predict effects of ...
Methamphetamine is a stimulant commonly abused in many parts of the United States. Most methamphetamine users are white men 18 to 25 years of age, but the highest usage rates have been found in native Hawaiians, persons of more than one race, Native Americans, and men who have sex with men. Methamphetamine use produces a rapid, pleasurable rush followed by euphoria, heightened attention, and increased energy. Possible adverse effects include myocardial infarction, stroke, seizures, rhabdomyolysis, cardiomyopathy, psychosis, and death. Chronic methamphetamine use is associated with neurologic and psychiatric symptoms and changes in physical appearance. High-risk sexual activity and transmission of human immunodeficiency virus are also associated with methamphetamine use. Use of methamphetamine in women who are pregnant can cause placental abruption, intrauterine growth retardation, and preterm birth, and there can be adverse consequences in children exposed to the drug. Treatment of methamphetamine
This study is part of an effort to develop treatments for methamphetamine abuse. Varenicline is a drug that changes levels of certain brain chemicals that may also be useful in helping people to stop using methamphetamine. Our goal is to determine the safety and effects of varenicline (1 and 2 mg, daily, vs. a placebo) when it is used before experimental administration of methamphetamine, on a number of physical and psychological measures; specifically blood pressure, heart rate, and how you feel after taking methamphetamine. The secondary purpose is to determine the effects of treatment with varenicline (1 and 2 mg daily), compared to treatment with placebo, on the reinforcing effects of methamphetamine by measuring methamphetamine self-administration in methamphetamine-dependent human volunteers ...
Crystal Meth Treatment in Burnsville, MN. Find phone numbers, addresses and information about Crystal Meth Treatment in Burnsville.
Methamphetamine can increase the release and even block the reuptake of the brain chemical dopamine. This leads to higher levels of dopamine in the brain which is common for drug abusers. Dopamine is responsible for reward, experience of pleasure, motivation and motor function. Since methamphetamine has the ability to release dopamine quickly in the brain, the reward sections of the brain experience an intense euphoria or a rush once the drug has been smoked, snorted, or injected into the body.. Using methamphetamine for a long period of time can significantly change how the brain is able to function. These functions can include reduced motor skills and impaired verbal learning. In other studies conducted, it also shows that chronic methamphetamine abusers have severe structural and even functional changes in the brain; in the memory and emotion areas. This is why many of the abusers of the drug have problems with emotional and cognitive situations.. Using methamphetamine for an extended period ...
Purchase Cheap Methamphetamine (Crystal Meth) For Sale Without A Prescription. , Methamphetamine) you may experience long-term effects such as: dizziness or lightheadedness; headache; blurred vision; fatigue; low energy; heartburn; nausea; vomiting; muscle aches; dizziness and nausea; vomiting, diarrhea, muscle pain or muscle cramps; headache; sleepiness and difficulty concentrating; tingling in your left arm or legs; increased sensitivity to light and heat; trouble sleeping; dizziness and shortness of breath; muscle weakness. Some symptoms of abuse with Methamphetamine are not completely eliminated after the next dose takes effect. , Methamphetamine) and stop using Methamphetamine for a minimum of 6 months. It is illegal to sell or give Methamphetamine online without medical clearance. However, you can buy Methamphetamine online with legal credit cards online, so you dont need to worry about paying a fee.
If you take methamphetamine, you should understand its potential for dependence and addiction. Learn the signs and symptoms and how to treat it.
Study Purpose: The purpose of the study was to provide information about markets, distribution, and use of methamphetamine in New York City, both inside and outside of the MSM (men who have sex with men)/gay community. The study had four specific aims. (1) Pilot a research design using mixed qualitative/quantitative data collection methods in New York City methamphetamine markets with participants recruited using Respondent Driven Sampling. (2) Document, describe, and analyze the demographics and methamphetamine abuse behaviors of a sample of methamphetamine market participants. (3) Document, describe, and analyze the social networks of New York City methamphetamine market participants as users, buyers, and sellers of methamphetamine. (4) Document, describe, and analyze the market behaviors of New York City methamphetamine market participants as users, buyers, and sellers of methamphetamine. Study Design: Researchers piloted a version of Respondent Driven Sampling (RDS) to recruit different ...
Methamphetamine use has increased substantially in the United States since the 1990s. Few studies have examined the healthcare service needs of women who use methamphetamine. This study describes unmet medical needs in a community-based sample of women who use methamphetamine in San Francisco, CA. Women who use methamphetamine were recruited in San Francisco and participated in a computer-assisted survey (N = 298 HIV-negative women).
Many people that struggle with Methamphetamine Abuse care for nothing but their high, so their unaware of the deadly Methamphetamine Abuse Symptoms.
Treatment for Crystal Methamphetamine (Meth) Addiction in Des Moines, IA. Find phone numbers, addresses and information about Treatment for Crystal Methamphetamine (Meth) Addiction in Des Moines.
Methamphetamine exists as two enantiomers. The S(+) form, which is also called "d" methamphetamine, is an ingredient in a few legitimate pharmaceutical products available only by prescription, and can be illicitly synthesized from (-) ephedrine or (+) pseudoephedrine. The S(+) or "d" form of methamphetamine is generally considered a drug of abuse. On the other hand, the R(-) form, which is also called l-desoxyephedrine or "l" methamphetamine, is the active ingredient in Vicks inhalers, is a metabolite of the anti-Parkinson drug Selegiline, and is not a drug of abuse. When a specimen gives a confirmed positive result for methamphetamine, this test can be ordered. This test separates the enantiomers and will provide percentage-based information to help determine the source of methamphetamine in the specimen. Note that this test does not provide quantitations; it only provides the percentage(s) of each methamphetamine found in the urine. The urine should be previously tested for methamphetamine and ...
Recent studies and research shows that People who use methamphetamine are almost five times more likely to have a stroke caused by a bleed in the brain, many of which are fatal. "We can add stroke to the list of terrible and devastating things that methamphetamine does," says Damian Zuloaga, of the University at Albany, New York.. Beyond the signature tooth decay known as "meth mouth", methamphetamine also increases heart rate and blood pressure, and can trigger heart attacks. The drug can lead to psychosis, and has been linked to anxiety disorders, depression, and problems with movement similar to those seen in Parkinsons disease.. A handful of studies have also linked methamphetamine use to strokes. To explore further, Julia Lappin and her colleagues at the Australian National Drug and Alcohol Research Centre in Sydney sifted through published research on the topic.. The team specifically looked for research into people under the age of 45 - a group less likely to be affected by age-related ...
In June 1994, the law enforcement community was starkly reminded of the violence that surrounds methamphetamine trafficking and the changing nature of the methamphetamine trade that is spreading across the United States. Drug Enforcement Administration (DEA) Special Agent Richard Fass, acting in an undercover capacity, was attempting to make a purchase of methamphetamine in a Glendale, Arizona, strip-mall when he was ambushed, shot, and killed by four methamphetamine traffickers whose sole intent was to rob him. This incident ended in violence and tragedy, as do so many of the cases involving methamphetamine. Law enforcement officers are not the only ones to suffer from the violence and danger associated with methamphetamine innocent victims all too often are brought into the fray. Over the past year, two separate methamphetamine-related tragedies have captured the publics attention. First, during the summer in New Mexico, a father, while high on methamphetamine, beheaded his 14-year-old son. ...
The Methamphetamine Treatment Project is collaborative effort between community and state to address the growing incidence of Methamphetamine use and abuse among youth in the state of South Dakota. The project is comprised of four phases, (1) stabilization, (2) intensive treatment, (3) structured living, and (4) community placement. Each phase will build on the proceeding phase. Most treatment programs do not adequately address the special needs of the Methamphetamine dependent adolescent client.
The article describes a study done by eight professors from UCLA where they observed methamphetamine users dental health. The article provides statistics from the study about the prevalence of gum disease and cavities in methamphetamine users.
Objective: To investigate whether methamphetamine use is associated with sexual risk behavior among adolescents. Method: A cross-sectional survey of 1,561 male and female high school students in Cape Town (mean age 14.9 years) was conducted using items from the Problem Oriented Screening Instrument for Teenagers (POSIT) HIV Risk Scale. Results: Nine percent of the students had tried methamphetamine and 30% of male and 17% of female students reported sexual debut. Multinomial logistic regression analyses showed that methamphetamine use in the past year was significantly associated with being in a higher HIV/STI risk category (RRR = 2.1, 95% CI: 1.10-4.03, p & 0.05). Conclusions: Methamphetamine use, coupled with a high HIV prevalence in South Africa, raises serious cause for concern about the potential for methamphetamine to further exacerbate the prevalence and spread of HIV in Cape Town. © 2012 Taylor and Francis Group, LLC.. ...
Mexican criminal groups have replaced traditional Asian criminal groups as the primary transporters of methamphetamine. Mexican criminal groups are the primary transporters of Mexico-produced methamphetamine as well as methamphetamine produced in California. Law enforcement officials report that Mexican criminal groups transport methamphetamine into Hawaii from the West Coast, primarily California. Mexican criminal groups transport both powdered and crystal methamphetamine. Some powdered methamphetamine is converted to crystal methamphetamine in Mexico and on the West Coast for transportation to Hawaii.. Traditional Asian transporters of crystal methamphetamine--primarily Korean, Japanese, Filipino, and Vietnamese criminal groups--also transport the drug into Hawaii, but to a lesser extent than during the mid-1980s to early 1990s. In the early 1990s law enforcement authorities in Hawaii dismantled several large Asian, primarily Korean, criminal groups that dominated the transportation of crystal ...
Within the past week, the Kern County Sheriffs Office Major Violators Unit concluded a Methamphetamine- to-Ice conversion narcotics lab investigation. The investigation led to a search warrant being served on Saturday, June 4th, at an auto-body repair business located near the intersection of Chamberlain and California Avenue, in Bakersfield. The search warrant resulted in the seizure of approximately four gallons of Methamphetamine solution and several pounds of Methamphetamine. The four gallons of Methamphetamine solution is estimated to contain/produce approximately 32 to 33 pounds of Methamphetamine. The estimated street value of the seized Methamphetamine is approximately 1.8 million dollars. Jose Cachu, age 44, of Lamont, and Jose Salinas, age 40, of Bakersfield, were both arrested at the business where the conversion lab was located. Both suspects were booked into the Kern County Jail for possession for sales, and manufacturing Methamphetamine. The investigation was a multi-agency ...
The prevalence of methamphetamine abuse during pregnancy in women seeking treatment tripled from 1994 to 2006, rising to 24% of all pregnant women admitted to federally funded treatment centers, according to the researchers. Eze and colleagues defined early adversity as the sum of multiple binary indicators, including self-reported maternal postnatal substance abuse, an annual household income less than $10,000, reported sexual or physical abuse by a caregiver, a maternal score on the Brief Symptom Inventory, maternal depression above average for the Beck Depression Inventory, quality of living environment below average on the HOME Inventory, community violence above average on the Lifestyle Interview, and social position below average for the Index of Social Position.. The researchers began recruiting for the Infant Development, Environment, and Lifestyle (IDEAL) longitudinal study in 2002. They enrolled 412 mother and infant pairs at four sites and identified participants as ...
TY - JOUR. T1 - Body dissatisfaction and methamphetamine use among HIV-positive gay and bisexual men. T2 - A pilot study. AU - Theodore, Peter S.. AU - Achiro, Richard P.. AU - Duran, Ron E.F.. AU - Antoni, Michael H.. PY - 2011/10/24. Y1 - 2011/10/24. N2 - Methamphetamine use is strongly associated with risky sex and increased reports of HIV and other sexually transmitted infections among gay and bisexual men (GBM) who attend dance/circuit parties. The psychological mechanisms underlying methamphetamine use in this subculture, however, remain unclear. These exploratory findings are from a 2004 dataset measuring body dissatisfaction and drug use among 42 HIV-positive GBM in South Florida who attended at least one bar/club/circuit party within 3 months of participating. A multivariate regression model revealed that body dissatisfaction accounted for a small but significant amount of variance in methamphetamine use. Treatment implications and recommendations for future research are ...
Last decade, positive drug tests among U.S. workers for methamphetamine had started to drop. That trend may be reversing, with positive rates dramatically higher in some states compared to others. The new statistics come from Quest Diagnostics annual report on U.S. worker drug use, based on more than six million urine tests collected from January-December 2010.. Positives for methamphetamine use in the U.S. general workforce dropped dramatically from 0.18% in 2006 to 0.11% in 2008. However, the rate remained the same in 2009 and 2010 at 0.10%.. Dr. Steven Shoptaw, a researcher who studies therapies for methamphetamine dependence, says, "Ive worked with patients who, paralyzed by the recession and juggling multiple jobs and family responsibilities, started using methamphetamine for its functional stimulant benefit.". Shoptaw notes that, even when its used as a stimulant by people who work more than one job, meth can wreak havoc on their judgment.. "For these sort of people, we now provide ...
Although at low levels, methamphetamine is being used by diverse groups of drug users in different ways, and this is clearly raising a variety of challenges and initial responses from service providers. Services currently identified as responding to problems include mental health, low-threshold, drug treatment, youth and sexual health.. Methamphetamine has long been used by problem drug users in both the Czech Republic and Slovakia, with injection as the most common route of administration. In the Czech Republic mental health care and residential treatment programmes applying the therapeutic community model have been at the centre of the response (Kalina, 2007). The focus has been on client assessment, the use of psychosocial interventions and medical treatment, and social reintegration initiatives. Services offering information, including harm reduction advice to methamphetamine users, are also available. An innovative intervention has involved the distribution of empty gelatine capsules by ...
TY - JOUR. T1 - Neurotoxic effects of methamphetamine. AU - Thrash, Bessy. AU - Karuppagounder, Senthilkumar S.. AU - Uthayathas, Subramaniam. AU - Suppiramaniam, Vishnu. AU - Dhanasekaran, Muralikrishnan. PY - 2010/1/1. Y1 - 2010/1/1. N2 - In Parkinsons disease, depletion of dopamine in the striatum leads to various symptoms such as tremor, rigidity and akinesia. Methamphetamine use has significantly increased in USA and around the world and there are several reports showing that its long-term use increases the risk for dopamine depletion. However, the toxic mechanisms of methamphetamine are not well understood. This study was undertaken to gain greater mechanistic understanding of the toxicity induced by methamphetamine. We evaluated the effect of methamphetamine on the generation of reactive oxygen species, mitochondrial monoamine oxidase, complex I & IV activities. Behavioral analysis evaluated the effect on catalepsy, akinesia and swim score. Neurotransmitter levels were evaluated using ...
From Pediatrics: OBJECTIVE: We evaluated behavior problems in children who were prenatally exposed to methamphetamine (MA) at ages 3 and 5 years. METHODS: The Infant Development, Environment, and Lifestyle study, a prospective, longitudinal study of prenatal MA exposure and child outcome, enrolled subjects postpartum in Los Angeles, California; Honolulu, Hawaii; Des Moines, Iowa; and Tulsa, Oklahoma. Prenatal…
In the study published in Addiction Biology, researchers from three Taiwanese institutions explored the potential role of declining levels of a protein called BDNF in promoting the brain damage found in chronic methamphetamine abusers and addicts. Under normal circumstances, BDNF provides the brain with critical protection by helping nerve cells grow, reach maturity and stay in good working order. In addition, the protein plays an essential role in basic brain functionality by supporting the chemical and physical adaptations required for learning new information and storing that information in memory.. For their study, the researchers recruited 59 people diagnosed with methamphetamine abuse, as well as a second group of 59 generally healthy individuals who did not use the drug. The methamphetamine abusers had stopped actively taking the drug and were in the early stages of withdrawal. Over a period of three weeks, the researchers used blood tests to measure the levels of BDNF in both groups of ...
The problem of methamphetamine use in todays society is an ever growing problem. Women of childbearing age are among this group, leading to an increasing number of children with prenatal methamphetamine exposure.. Christine Cloak, Ph.D., of the University of Hawaii, and colleagues findings are reported online in Neurology. The researchers did MRI scans on 29 methamphetamine-exposed children 3 to 4 years old, recruited from local hospitals, drug rehabilitation centers, and the community. Using detailed interviews of the mothers, the cumulative gestational methamphetamine exposure reported averaged 58 g over 2.5 trimesters, but varied widely.. Methamphetamine has been shown to cross the placenta and impact overall fetal growth. The drug is known to act on dopamine receptors that regulate corticogenesis and are present in the brain as early as the first trimester. It also affects other catecholamine systems involved in brain development.. Cloak and colleagues found that prenatal exposure to meth ...
purchase methamphetamine crystal meth in Belo Horizonte Brazil Barrytaking, purchase methamphetamine crystal meth in Angra Dus Reis Brazil thishurtsaid
... is here at Pinnacle Peak Recovery. People who use methamphetamine usually say that this drugs pleasurable high keeps ...
Methamphetamine, generally described as "meth," is a highly-addictive neurotoxic energizer that is commonly described as "one of the most hazardous medication on earth," due to the broad schedule, simplicity of usage, and also capacity to produce the medicine from normal home products. Most often, methamphetamine comes in two forms, "Crystal Meth" and also "powdered meth," both generate comparable impacts on the customer.. Meth generates a false sense of well-being and joy. It gives the user a thrill, and an increase in feelings of power, confidence, and also wakefulness. These results generally last six to eight hrs, however can be sustained for upwards of twelve hrs.. Methamphetamine is merely and also cheaply made using different family products in about two days- start to complete. The key component in methamphetamine is pseudoephedrine or ephedrine, both of which are discovered in a wide variety of over the counter chilly treatments.. ...
Alcohol and meth have different functions. Alcohol is a sedative - a downer - and works as a central nervous system depressant, also called a CNS depressant. Its effects include nausea, impaired thinking, and slowed cardiovascular functioning. When consumed in large quantities, alcohol can cause dramatic mood swings, slurred speech, loss of motor skills coordination, and alcohol poisoning.. Methamphetamine, or meth, is a stimulant - an upper - and considered one of the most potent of its kind. It stimulates the central nervous system, leading to the occurrence of high blood pressure, increased energy, amplified heart rate, and euphoria. Medically, methamphetamine is an FDA-approved medication for treating ADHD and exogenous obesity in both children and adults.. Being addicted to methamphetamine and alcohol can increase the risk for alcohol poisoning. According to the New Research on Methamphetamine Abuse, ethanol or alcohol attenuates the effects of methamphetamine and slows down the metabolism ...
Methamphetamine addiction has primarily afflicted persons who are white and rural inhabitants of Western and Midwest states. In addition, urban-dwelling gay males are experiencing an alarming increase in methamphetamine abuse, resulting in rapid spread of HIV infection fueled by unsafe sexual practices. Thus, medical, mental health, and other healthcare professionals working in a variety of settings with a variety of patient populations are likely to encounter patients who have used or are currently using methamphetamine. The knowledge gained from reading and comprehending the contents of this course can greatly assist the psychologist in identifying, treating, and providing an appropriate referral to patients who misuse methamphetamine.
Amphetamine, discovered before methamphetamine, was first synthesized in 1887 in Germany by Romanian chemist Lazăr Edeleanuwho named it phenylisopropylamine.[77][78] Shortly after, methamphetamine was synthesized from ephedrine in 1893 by Japanesechemist Nagai Nagayoshi.[79] Three decades later, in 1919, methamphetamine hydrochloride was synthesized by pharmacologist Akira Ogata via reduction of ephedrine using red phosphorus and iodine.[80] During World War II, methamphetamine was used extensively by the Axis forces for its stimulant effects.[78][81] Obetrol, patented by Obetrol Pharmaceuticals in the 1950s and indicated for treatment ofobesity, was one of the first brands of pharmaceutical methamphetamine products.[82] Due to the psychological and stimulant effects of methamphetamine, Obetrol became a popular diet pill in America in the 1950s and 1960s.[82] Eventually, as the addictive properties of the drug became known, governments began to strictly regulate the production and distribution ...
Background and Aim: Methamphetamine causes damage in different body organs. The aim of this study was to investigate the effects of methamphetamine on morphometric changes and biochemical parameters in kidney of adult mice. Material and Methods: In this experimental study, 56 mice were randomly divided into 7 groups: control and 6 experimental ...
S-(+)-methamphetamine hydrochloride ("ice") is abused by smoking (inhaling the vapors of the material). Male human volunteers inhaled the drug from a pipe heated at 300 degrees-305 degrees C for an average inhaled dose of 21.8 +/- 0.3 (SE) mg. The same volunteers were given an intravenous injection of 15.5 mg of S-(+)-methamphetamine hydrochloride. Methamphetamine and its metabolite amphetamine were analyzed in plasma, saliva, and urine by gas chromatography. The bioavailability of smoked methamphetamine was 90.3 +/- 10.4%. (Oral bioavailability calculated from this study and a previous one was 67.2 +/- 3.1%). The geometric mean plasma half-life was 11.1 hr for smoked methamphetamine and 12.2 hr for the intravenous drug. These values agreed with urinary excretion rate data. The volume of distribution in the elimination phase was 3.24 +/- 0.36 liter/kg for the smoked dose and 3.73 +/- 0.59 liter/kg for the intravenous dose. The mean residence times were 11.5 +/- 0.5 hr and 11.3 +/- 1.74 hr for ...
The Comprehensive Methamphetamine Control Act of 1996 is a bill (S. 1965) enacted into law (PL 104-237) by the 104th Congress of the United States. It mandated registration of persons trading in list I chemicals from the DEA list of chemicals A fee for such registration was initially $595 but later reduced to $116. It is regarded as one of the major drug laws in the United States. The Comprehensive Methamphetamine Control Act was composed as five titles sanctioning legislative authority for the control, exportation, importation, and manufacturing of methamphetamine substances and precursor chemicals. Congressional assessment with regards to methamphetamine substances and precursor chemicals - The 104th U.S. Congress finds the following : (1) Methamphetamine is a very dangerous and harmful drug. It is highly addictive and is associated with permanent brain damage in long-term users. (2) The abuse of methamphetamine has increased dramatically since 1990. This increased use has led to devastating ...
Methamphetamine affects your brain. In the short term, meth causes mind and mood changes such as anxiety, euphoria, and depression. Long-term effects can include chronic fatigue, paranoid or delusional thinking, and permanent psychological damage. Methamphetamine affects your body. Over "amping" on any type of speed is pretty risky. Creating a false sense of energy, these drugs push the body faster and further than its meant to go. It increases the heart rate, blood pressure, and risk of stroke. Methamphetamine affects your self-control. Meth is a powerfully addictive drug that can cause aggression and violent or psychotic behavior. Methamphetamine is not what it seems. Even speed drugs are not always safe. Giga-jolts of the well-known stimulants caffeine or ephedrine can cause stroke or cardiac arrest when overused or used by people with sensitivity to them. Methamphetamine can kill you. An overdose of meth can result in heart failure. Long-term physical effects such as liver, kidney, and lung ...
People who abused methamphetamine or other amphetamine-like stimulants were more likely to develop Parkinsons disease than those who did not, in a new study from the Centre for Addiction and Mental Health (CAMH).. The researchers examined almost 300,000 hospital records from California covering 16 years. Patients admitted to hospital for methamphetamine or amphetamine-use disorders had a 76 per cent higher risk of developing Parkinsons disease compared to those with no disorder.. Globally, methamphetamine and similar stimulants are the second most commonly used class of illicit drugs.. "This study provides evidence of this association for the first time, even though it has been suspected for 30 years," said lead researcher Dr. Russell Callaghan, a scientist with CAMH. Parkinsons disease is caused by a deficiency in the brains ability to produce a chemical called dopamine. Because animal studies have shown that methamphetamine damages dopamine-producing areas in the brain, scientists have ...
The study reviewed records of nearly 820,000 people in California who during hospitalization were diagnosed as abusers or dependent upon alcohol, cannabis, cocaine, methamphetamine, or opioids, within the 16-year period from January 1990 through December 2005. Death records also were reviewed during this period. For subjects who died within the study period, the average duration between index hospitalization and death ranged from 7.4 - 10.7 years, with mean duration for methamphetamine abusers of 8.5 years (4122 deaths). The study did not include polydrug abusers (who were diagnosed as abusing more than one substance ...
Methamphetamine addiction is a brain disorder and a chronic condition in which a person cannot stop using the drug methamphetamine, or meth.
Lightsense is providing analytical tools to detect illicit drugs with high accuracy and sensitivity. The first product is a methamphetamine detector (scanner) that can detect powder or crystalline forms of methamphetamine on almost any surface, including skin, clothing, plastics, wood, masonry and metals.. A unique feature of the Lightsense methamphetamine scanner is its ability to accurately detect methamphetamine in mixtures of other substances, often used as disguise, at concentrations down to less than 1%, far beyond the capabilities of any competing spectroscopic technique.. The Lightsense methamphetamine scanner has successfully gone through a series of critical tests by federal and local law enforcement agencies and is expected to be an important tool for narcotics divisions of federal, state and local law enforcement. The handheld device is the size of a smartphone and can be carried and concealed easily, giving law enforcement officers an advantage in combating drug crime. The test ...
Methamphetamine is a highly addictive psychostimulant drug that is chemically related to amphetamine. Methamphetamine can produce euphoria and stimulant effects like those from other stimulants such as cocaine.
Methamphetamine or "meth" is a powerful, tremendously addictive psychomotor stimulant.. Most of the methamphetamine available on the street is made in secret, makeshift laboratories that may be found in ordinary kitchens, bathrooms, basements, or sheds. The ingredients used to make meth are fairly inexpensive, although they can be difficult to obtain. The process for making ("cooking") methamphetamine is not difficult to learn, so uneducated drug dealers can make the drug without any scientific training. Making methamphetamine is also incredibly dangerous; toxic fumes fill the labs, and explosions and fires are constant dangers.. Methamphetamine is a white, odorless, bitter-tasting crystalline powder that easily dissolves in water or alcohol. Another common form of the drug is called crystal meth, or "ice," because it comes in large chunky crystals that look like ice chunks or rock candy. The powder form of the drug may be snorted, swallowed, or diluted and injected. The "crystal" form of the ...