TY - JOUR. T1 - Dietary D-allulose alters cholesterol metabolism in Golden Syrian hamsters partly by reducing serum PCSK9 levels. AU - Kanasaki, Akane. AU - Jiang, Zhe. AU - Mizokami, Takuya. AU - Shirouchi, Bungo. AU - Iida, Tetsuo. AU - Nagata, Yasuo. AU - Sato, Masao. PY - 2019/9/1. Y1 - 2019/9/1. N2 - D-Allulose, a C-3 epimer of D-fructose, is a rare sugar reported to be a non-caloric sweetener having several health beneficial effects including anti-hyperglycemia and anti-obesity. However, the impact of dietary D-allulose on cholesterol metabolism remains unclear. Therefore, we studied the effects of D-allulose on the cholesterol metabolism of Golden Syrian hamsters, an animal model with a lipid metabolism similar to that of humans. Hamsters received either normal diet (ND) or high-fat diet (HFD) with or without 3% D-allulose for 4 or 8 weeks. While there were no significant differences in total serum cholesterol levels between the groups, D-allulose significantly increased HDL-cholesterol ...
TY - JOUR. T1 - Effect of cholesterol feeding on DNA damage in male and female Syrian hamsters. AU - Turley, E. AU - Armstrong, NC. AU - Wallace, JMW. AU - Gilmore, WS. AU - McKelvey-Martin, VJ. AU - Allen, J. AU - Strain, JJ. PY - 1999/1. Y1 - 1999/1. N2 - Cholesterol oxides are cytotoxic and have been implicated in many disease processes; however, it has been proposed that cholesterol oxides result from cholesterol acting as a sacrificial antioxidant. In this study, the effect of dietary cholesterol on DNA damage, assessed by the alkaline comet assay, was examined in male and female Syrian hamsters. Animals were fed ad libitum a modified AIN-76 diet (control) or a diet with 0.5% cholesterol for 10 weeks. Following the 10-week feeding period, there was no significant difference in body weight between cholesterol-fed and control animals. Cholesterol feeding resulted in significant liver hypertrophy, and increased plasma total and HDL cholesterol in both male and female animals compared with ...
Goat anti-Golden Syrian hamster IgG recognizes Golden Syrian hamster IgG whole molecule. This secondary antibody was purified using antigen affinity chromatography. The antibody is conjugated with Rhodamine. Golden Syrian hamster IgG whole molecule (PAB10592) - Products - Abnova
Rabbit anti-Golden Syrian hamster IgG recognizes Golden Syrian hamster IgG whole molecule. This secondary antibody was purified using antigen affinity chromatography. Golden Syrian hamster IgG whole molecule (PAB9233) - Products - Abnova
We attempted to alter the inherited myocardial damage and loss of contractility of the cardiomyopathic Syrian hamster (strain U-MX7-1) by giving cardiac drugs that altered intracellular calcium and myocardial workload. Thirty-seven 21-day-old cardiomyopathic and thirty-seven 21-day-old normal hamsters were divided into five groups each: verapamil-, propranolol-, digoxin-, hydralazine-, and saline-injected. On their 90th day of life, the hamsters were killed. Of the five cardiomyopathic groups, only verapamil reduced myocardial damage. When both "control" and cardiomyopathic hamsters were treated with saline, digoxin, or propranolol, the cardiomyopathic hamsters had significantly less contractile force, maximal rate of force development, and maximum velocity of unloaded shortening. When both groups were treated with verapamil or hydralazine, there were no significant group differences in the indices of contractility. However, when saline-treated cardiomyopathic hamsters were compared with ...
It has been shown previously that normal Syrian hamster embryo cells are neoplastically transformed by transfection with two cooperating oncogenes, v-myc plus v-Ha-ras. Karyotypic analyses of the cells from the tumors revealed a nonrandom chromosome change, monosomy of chromosome 15. In order to clarify the role of chromosome loss in these tumor cells with defined oncogene alterations, molecular and cytogenetic studies were performed on hybrids between normal Syrian hamster embryo cells and ras/myc tumor cells. Following fusion of the tumor cells with the normal cells which are not immortal, the majority of the cell hybrids senesced after ≤20 population doublings indicating that immortality was recessive. Some of the hybrids escaped senescence and grew indefinitely. These immortal hybrid cells retained the expected numbers of chromosome 15 indicating that escape from senescence did not involve loss of this chromosome. The tumorigenicity and anchorage-independent growth of the nonsenescent ...
Endothelin-1 (ET-1) is produced by endothelial cells and can stimulate either the ET A or the ET 8 receptors. The role of ET-1 and the identity of the endothelin receptors involved in mediating tone in the mesenteric small veins of the -Golden Syrian hamster are not known. ET-1. induces venoconstriction, thereby increasing the preload to the heart in congestive heart failure. However, mechanisms mediating contraction to ET-1 in the mesenteric small veins of the cardiomyopathic hamsters in the early and late stages of CHF are not known. Therefore, mechanisms mediating ET-1 induced contraction were determined in the mesenteric small veins of the Golden Syrian and cardiomyopathic hamsters in the early and late sta~es of CHF. Baseline intraluminal diameter of small veins was measured before anci after treatment with either ET A or ET 8 receptor antagonists. .ET-1 induced contraction was higher in the · early stage of CHF, while it was· decreased in the late stage of CHF. Blockade of the ET A ...
Endothelin-1 (ET-1) is produced by endothelial cells and can stimulate either the ETa or the ETB receptors. The role o f ET-1 and the identity of the endothelin receptors involved in mediating tone in the mesenteric small veins of the Golden Syrian hamster are not known. ET-1 induces venoconstriction, thereby increasing the preload to the heart in congestive heart failure. However, mechanisms mediating contraction to ET-1 in the mesenteric small veins of the cardiomyopathic hamsters in the early and late stages of CHF are not known. Therefore, mechanisms mediating ET-1 induced contraction were determined in the mesenteric small veins o f the Golden Syrian and cardiomyopathic hamsters in the early and late stages of CHF. Baseline intraluminal diameter of small veins was measured before and after treatment with either ETa or ETB receptor antagonists. ET-1 induced contraction was higher in the early stage o f CHF, while it was decreased in the late stage of CHF. Blockade of the ETA receptor ...
Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE-independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial association with multiprotein coactivator complexes through LXXLL motifs of their respective components. Mutual transrepression occurs between the estrogen receptor (ER) and NF-kappa-B in a cell-type specific manner. Decreases NF-kappa-B DNA-binding activity and inhibits NF-kappa-B-mediated transcription from the IL6 promoter and displace RELA/p65 and associated coregulators from the promoter. Recruited to the NF-kappa-B response element of
Acts as a transcriptional repressor. Binds to E-box sequences in the immunoglobulin heavy chain enhancer as well as in the regulatory regions of many other tissue-specific genes. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5-CANNTG-3). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs (By similarity).
Following treatment of Syrian hamster embryo cells with benzo(a)pyrene, the time required for the expression of enhanced fibrinolytic activity was examined. For this study, the fibrin-agarose overlay method was developed to distinguish the activity of normal and transformed colonies of hamster cells. Colonies possessing enhanced fibrinolytic activity were not observed 8 days after treatment, but they were observed following one passage (2 weeks after treatment). Morphologically transformed colonies, which exhibited no enhanced fibrinolytic activity, were observed 8 days following treatment. In contrast to these two early changes, cells capable of growth in soft agar were observed much later (6 to 8 weeks after treatment). Untreated Syrian hamster embryo cells generally senesced and did not exhibit enhanced fibrinolytic activity. Approximately 1 of 10 untreated cultures escaped senescence and evolved as a continuous cell line; such cultures frequently exhibited enhanced fibrinolytic activity. ...
The parent line of BHK-21(C-13) was derived from baby hamster kidneys of five unsexed, 1-day-old hamsters in March, 1961, by I.A. Macpherson and M.G.P. Stoker. Following 84 days of continuous cultivation, interrupted only by an 8-day preservation by freezing, clone 13 was initiated by single-cell isolation.
The parent line of BHK-21(C-13) was derived from baby hamster kidneys of five unsexed, 1-day-old hamsters in March, 1961, by I.A. Macpherson and M.G.P. Stoker. Following 84 days of continuous cultivation, interrupted only by an 8-day preservation by freezing, clone 13 was initiated by single-cell isolation.
Normal Hamster (Syrian) control serum (non-immunized) Mixed breed serum GC-NGHS-5 Normal Hamster (Syrian) control serum (non-immunized) Mixed breed serum GC-NGHS-5
Previous work on the early development of the golden hamster includes the investigation of Ochs (1908), Graves (1945) and Ward (1948), all at the level of the light microscope. Austin (1963) has examined the ultrastructure of the oocytes of the golden hamster while Enders & Schlafke (1965) have observed the pre-implantation stages of pregnancy.. The ultrastructure of implantation has been studied in two other species of myomorph rodents: the mouse (Potts, 1966a; Reinius, 1967) and the rat (Enders & Schlafke, 1967).. Implantation is taken as beginning when the zona pellucida is lost and the trophoblast is in contact with the uterine epithelium throughout its circumference. This takes place at between 80-100 h post coitum. Previous studies have been made on specimens embedded in paraffin, and the shrinkage which occurs with this method of preservation has caused implantation to appear to begin considerably later than this:Graves (1945) gives it as beginning at 5 days, Ward(1948) as 4 days 8 ...
Gentaur molecular products has all kinds of products like :search , Zyagen \ Hamster Heart cDNA \ AD-801 for more molecular products just contact us
Matthew D Johnson is the author of this article in the Journal of Visualized Experiments: Measuring In Vivo Changes in Extracellular Neurotransmitters During Naturally Rewarding Behaviors in Female Syrian Hamsters
First off, a VERY IMPORTANT NOTE. Mulder is a Roborovski hamster, which is the smallest of the dwarf hamsters. When Scully died, he weighed 22g, or 0.78oz; robos are usually less than 30g, or 1.06oz. Other dwarf hamsters are slightly larger, and can weigh up to 2.5oz. Syrian hamsters, on the other hand, usually weigh 5-7oz. This house is a little less than 450 square inches, which is a decent size for a dwarf hamster, but would be entirely too small for a Syrian hamster. If you need a house for a Syrian hamster, I highly recommend that you consider adapting these instructions for a much larger table, such as the Lack coffee table or two or more connected Lack side tables ...
Sreekumar, A and Acharya, KK and Lalitha, HS and Indi, SS and Bali, P and Seshagiri, PB (2005) Germ cell-specific localization of immunoreactive riboflavin carrier protein in the male golden hamster: appearance during spermatogenesis and role in sperm function. In: Reproduction, 129 (5). pp. 577-587. ...
... , Goat Polyclonal, Fluorescein (FITC) validated in IF, FC (ASR1712), Abgent
Careful consideration.. - Not all species of hamster can be housed in groups. Syrian and Chinese hamsters in particular are not naturally sociable and are better kept on their own. Under appropriate conditions and if care is taken, Dwarf hamsters can be group housed.. - If you are housing hamsters in groups, take great care to make sure the groups are compatible. Hamsters are generally solitary animals, and can be aggressive towards other hamsters. When aggression occurs between hamsters it can be very dramatic and lead to serious injury or even death. Housing Hamsters in Groups (PDF 231KB).. ...
Retinoid X Receptor α (RXRα) regulates intracellular receptor signaling pathways involved in, among others, glucose and lipid metabolism and has potential to impact multiple risk factors associated with the metabolic syndrome.We report the pharmacological activity of CNX-013-B2, a potent and selective RXRα agonist with pan-PPAR activity, upon qd dosing of C57BL/6j DIO mice (2.5-10mg/kg for 10 weeks) and Syrian Golden Hamsters (10mg/kg for 12 weeks) on high cholesterol diet. In comparison with control DIO animals treatment with CNX-013-B2 resulted in a 10-12% reduction in fasting glucose (196.30±3.16 Vs 153±3.83 mg/dl), 20% in fasting serum triglycerides, 25% free fatty acids, 20% fasting glycerol, 25% total cholesterol and 43% LDLc.Similarly in comparison with control animals treated hamsters displayed a significant 20% and 45% decrease in serum total cholesterol and LDLc, respectively, and a reduction in fatty streaks in thoracic aorta. In DIO animals treatment with CNX-013-B2 resulted in ...
Retinoid X Receptor α (RXRα) regulates intracellular receptor signaling pathways involved in, among others, glucose and lipid metabolism and has potential to impact multiple risk factors associated with the metabolic syndrome.We report the pharmacological activity of CNX-013-B2, a potent and selective RXRα agonist with pan-PPAR activity, upon qd dosing of C57BL/6j DIO mice (2.5-10mg/kg for 10 weeks) and Syrian Golden Hamsters (10mg/kg for 12 weeks) on high cholesterol diet. In comparison with control DIO animals treatment with CNX-013-B2 resulted in a 10-12% reduction in fasting glucose (196.30±3.16 Vs 153±3.83 mg/dl), 20% in fasting serum triglycerides, 25% free fatty acids, 20% fasting glycerol, 25% total cholesterol and 43% LDLc.Similarly in comparison with control animals treated hamsters displayed a significant 20% and 45% decrease in serum total cholesterol and LDLc, respectively, and a reduction in fatty streaks in thoracic aorta. In DIO animals treatment with CNX-013-B2 resulted in ...
BioAssay record AID 84692 submitted by ChEMBL: Compound was evaluated in vivo for the cholesterol lowering activity in hamster model.
Zyagen : Hamster Tissue Total Protein - Antibodies Kits, Reagents & Biochemical Tissue Sections RNA Products cDNA Products Genomic DNA Products Tissue Lysates Products Premade Northern Blots Premade Western Blots Recombinant Proteins & Peptides Tissue Microarrays
Gentaur molecular products has all kinds of products like :search , Zyagen \ Hamster Tissue Total RNA, Adult Tissues Ovary* \ AR-406 for more molecular products just contact us
sundoc Migration; Titel: Vergleichende Untersuchungen zu Morphometrie, Verhalten und genetischer Variabilität einer Labor- und Wildpopulation des Goldhamsters (Mesocricetus au [...], Verfasser: Krause, Sabine, 2008 ; Halle, Saale : Universitäts- und Landesbibliothek Sachsen-Anhalt
Shop a large selection of products and learn more about CD49b Hamster anti-Mouse, BB700, Clone: HMα2, BD Optibuild 50μg; BB700 50μg; BB700.
BioAssay record AID 51634 submitted by ChEMBL: Concentration required for the inhibition of Cholesterol O-acyl transferase from hamster liver.
Hamster IgG negative control is suitable for use as a negative control for the measurement of non-specific binding of Syrian hamster monoc
Fiber and Swann observed significant increments in neuronal Fos-IR in both the MOB and the AOB of male hamsters 1 h after exposure to female hamster vaginal
A long haired Syrian hamster needs daily brushing, with a special hamster brush from a pet store or even a soft toothbrush (1, 9). Some sources say all hamsters need daily brushing (9); all appreciate a dish of sand bought from a pet store to roll in, removing grease from their coats. Practice good handling daily to get your hamster used to this and be extremely, super-gentle, they truly are delicate little critters. Pick them up with the upmost care with both your hands as a scoop, and only handle them over a flat, soft surface - never at height in case they fall or jump. Be aware if you wake them in the daytime, they may bite - because as far as their concerned, its the middle of the night and youre simply a weird and intrusive predatory giant hand-thing looming around them. With gentle persistence, you can establish a daily grooming session to keep coats healthier and shinier.. Your accessories starter-kit now consists of a drip-feed water bottle, nesting box, toys and a brush. Youll ...
Just like humans and most animals, hamsters are susceptible to parasites -- organisms that live either on or inside a host, getting their nutrient supply from the host and often causing the host harm or discomfort. Parasites can be difficult to detect in hamsters and, though they are generally not extremely dangerous, ...
Golden Larva Egg is a potion. Obtaining Dropped by Green Larva Orange Larva Blue Larva Immature Blue Larva Immature Orange Larva Immature Green Larva Uses Consume Gives a Little Golden Larva (required to access the Larva Dungeon) Golden Larva Egg Effects : Gives a Little Golden Larva...
Secretion and Regulation of ApoB48 by Primary Hamster Intestinal EnterocytesIntestinal Enterocytes B C LabeledApoB48(%control) LabeledApoB48(%control) 0 20 40 …
The best Leupold Golden Ring binoculars are top rated birding binoculars without sky-high prices. Read our Leupold Golden Ring reviews & find the best for you
Complete your Golden State Records collection. Discover whats missing in your Golden State Records discography. Shop Golden State Records Vinyl and CDs.
The epaxial muscles of the golden hamster (pages 319-334). Mohamad S. Salih and George C. Kent Jr.. Version of Record online: 3 FEB 2005 , DOI: 10.1002/ar.1091500314. ...
The United States launched a direct attack against the government of Syrian President Bashar al-Assad on Thursday by firing a barrage of cruise missiles at an air base.
On the day of the Syrian governments latest round of elections, dismissed as fraudulent by the regimes opponents, the opposition decided to form yet another governing body called the
This is your website: Support it. The Syrian Outcome Has Departed the Script The CIA and presstitutes will re-write the history Paul Craig Roberts Stephen
Three years of extremely violent war have ripped apart towns, villages, hospitals, clinics-everything that Syrians relied on for their existence.
Warplanes struck the Syrian town of Khan Sheikhoun early Saturday, battering residents still reeling from the Bashar al-Assad regime
Business Standard News: Company History : Golden Proteins Company History, Golden Proteins updates and more at Business Standard news. | Page 1
Sunrise over fields of wheat Growing, glowing, golden yield A beautiful place of transcendant peace. Stroll through the golden fields Meditating on how good it feels A million miles from all areas and worry Life no longer in a hurry As I meet my soul group who are yonder I realise life I am beyond…
A Googler declares: Its Golden age for hardware guys. I say, Really? We all sense radical changes afoot. I asked young engineers/researchers what they see as bottlenecks to innovation.
Overview The DayDreamer PowerPillow™ lift chair is the perfect combination of comfort and innovation, and now even more so with the addition of Goldens ultra-comfy contoured Cloud...
The Remarkable Golden Ratio Part 1 is an introduction to what the Golden Ratio is numerically and why it is important to be observed in design.
How to Make Baby Dwarf Hamster Food. Baby hamsters do best when they are fed mothers milk; before ten days old they will very likely die without it. However, a good hamster parent will provide the mother with sufficient nutrition for...
The authors of the article suggest that for enzymes using ATP as a co-factor a screening library with HA ~ 19 (divide HA for ATP by golden ratio) should be used. The average HA for an NMR or crystallographic screening library is typically lower than this and the figure of 19 will be close to the upper limit for molecular size. NAD (HA = 44) and NADP (HA = 48) are significantly larger molecules than ATP so its not clear what size fragments the authors would recommend for enzymes that use the former two as cofactors. A number of the entries in Table 1 are proteases for which the natural substrates tend to be extremely large on the fragment size scale. ...