Since Young reported a lateral discoid meniscus, many cases have been found. Discoid lateral meniscus is more common among Asians than that among Caucasians [15-17]. The incidence rate of discoid medial menisci reported was from 0.03% to 0.3% [6, 11]. By using MRI, it is now possible to diagnose meniscus condition noninvasively [18]. Blacksin et al. [9] described the first case of bilateral discoid medial menisci diagnosed using MRI. Yanez-Acevedo reported a case of bilateral discoid lateral menisci and unilateral discoid medial menisci, thus three discoid menisci in an 11-year-old girl [19].. Dickason has reported the large series of 10 medial discoid menisci in which there was one 22-year-old man with bilateral massive discoid menisci [6]. The incidence of discoid menisci is difficult to be estimated since the rate of asymptomatic patients is high. Yaniv and Blumberg cited that the incidence of discoid meniscus ranges from 0.4% to 17% for the lateral and 0.06% to 0.3% for the medial ...
The Meniscus is the most commonly injured part of the knee. In young people a meniscus tear is usually caused by a traumatic twisting injury. In older people, in addition to traumatic injury, tears are often caused by weakness of the meniscus caused by degenerative changes in the knee joint. Meniscus tears are often described by their position: anterior or posterior, which meniscus: medial or lateral and the type of tear. Here are some examples…. A Medial Meniscus Tear describes a tear on medial meniscus often caused traumatically by sudden changes of direction and force in sports like football, soccer, basketball, volleyball and skiing. They can also be caused by repetitive use injuries like distance running and cycling and degenerative changes to the knee in older patients. Medial Meniscus Tears respond very well to Stem Cell Therapy.. Bucket Handle Meniscus Tear: The entire inner rim of the medial meniscus can be torn in what is called a bucket handle tear. These tears usually occur in an ...
Current meniscus repair techniques are only effective in treating lesions located in the peripheral vascularized region of the meniscus. Thus total or subtotal meniscectomy was still inevitable for the severe meniscus tears. Identifying patients at high risk for total/subtotal meniscectomy may allow for interventions after meniscus injury. However, few study has evaluated the risk factor associated with the total/subtotal meniscectomy, especially comparing the difference between medial and lateral meniscus. The purpose of the present study was to evaluate the risk factor of total or subtotal meniscectomy for respective medial and lateral meniscus injury. Analyzing data from a big sample available in an Asian patient database, we found different risk factors associated with total/subtotal meniscectomy for respective medial and lateral side. According to the results, meniscus tears should be treated as soon as possible to reduce the risk of total or subtotal meniscectomy, especially for the medial ...
The rationale for cutting away damaged meniscal tissue is based on the premise that the injured or damaged parts of the meniscus are the primary cause of the patients pain and discomfort. More likely, the knee pain is explained by the presence of early degenerative changes (including degenerative meniscal tissue) or established osteoarthritis in the knee and not because of a direct link between pain and meniscal damage per se.4 Meniscal tears are common in the symptom-free general middle-aged and older population with and without signs of radiographic knee osteoarthritis.5 6 Similarly, in patients with knee trauma, meniscal tears are frequently seen in the uninjured contralateral leg.7 Such studies debunk the explanation that meniscal tears always cause pain; the simple car mechanic analogy-cutting tissue away-does not apply ...
article{3d1b2282-e5e4-4d96-9f14-c74797ca0eb1, abstract = {,p,Objective: To compare consultation rate for knee osteoarthritis (OA) after meniscus repair, arthroscopic partial meniscectomy (APM), and in general population, respectively. Method: We identified patients aged 16-45 years having had meniscus surgery due to traumatic meniscus tear in 1998-2010 in southern Sweden by a healthcare register. Patients were followed from surgery until a diagnosis of knee OA, relocation, death, or December 31st, 2015. We studied the consultation rate for knee OA compared to the general population. Results: We identified 2,487 patients diagnosed with traumatic meniscus tear (mean [SD] age 30.5 [8.6] years); 229 (9.2%) of them had had meniscus repair. The absolute risk of having consulted for knee OA during the study was 17% after APM, 10.0% after meniscus repair, and 2.3% in the general population. Hazard ratio (HR) (95% confidence interval (CI)) for knee OA after repair vs APM was: 0.74 (0.48, 1.15). Excluding ...
MR is the imaging study of choice to evaluate the menisci. The normal meniscus is devoid of signal on all imaging sequences. Proton density or T1 weighted coronal and sagittal images are the most accurate for evaluation of the menisci.. The lateral meniscus tears less commonly than the medial meniscus. A discoid lateral meniscus, which is thought to be a congenital variant, occurs much more commonly on the lateral meniscus. A discoid meniscus can be symptomatic, in and of itself, causing joint locking and joint line tenderness. The abnormal biomechanics of the discoid meniscus also makes it prone to tearing. It is diagnosed on sagittal images, when 3 or more consecutive segments including the body are identified. On coronal images, it is diagnosed when the horizontal measurement between the free margin and the periphery of the body is more than 1.4 cm.. A tear is diagnosed when there is increased signal within the meniscus that extends to the articular surface. If there is increased signal ...
Objectives To investigate the association between meniscal pathology and incident or enlarging bone marrow lesions (BML) in knee osteoarthritis.. Methods The authors studied subjects from the Multicenter Osteoarthritis Study aged 50-79 years either with knee osteoarthritis or at high risk of the disease. Baseline and 30-months magnetic resonance images of knees (n=1344) were scored for subchondral BML. Outcome was defined as an increase in BML score in either the tibial or femoral condyle in medial and lateral compartments, respectively. The authors defined meniscal pathology at baseline as the presence of either meniscal lesions or meniscal extrusion. The risk of an increase in BML score in relation to meniscal status in the same compartment was estimated using a log linear regression model adjusted for age, sex, body mass index, physical activity level and mechanical axis. In secondary analyses the investigators stratified by ipsilateral tibiofemoral cartilage status at baseline and ...
BACKGROUND: Diagnostic imaging represents the fastest growing segment of costs in the US health system. This study investigated the cost-effectiveness of alternative diagnostic approaches to meniscus tears of the knee, a highly prevalent disease that traditionally relies on MRI as part of the diagnostic strategy. PURPOSE: To identify the most efficient strategy for the diagnosis of meniscus tears. STUDY DESIGN: Economic and decision analysis; Level of evidence, 1. METHODS: A simple-decision model run as a cost-utility analysis was constructed to assess the value added by MRI in various combinations with patient history and physical examination (H&P). The model examined traumatic and degenerative tears in 2 distinct settings: primary care and orthopaedic sports medicine clinic. Strategies were compared using the incremental cost-effectiveness ratio (ICER). RESULTS: In both practice settings, H&P alone was widely preferred for degenerative meniscus tears. Performing MRI to confirm a positive H&P ...
There are two menisci in the knee. They sit between the thigh bone and the shin bone. While the ends of the thigh bone and the shin bone have a thin covering of soft hyaline cartilage, the menisci are made of tough fibrocartilage and conform to the surfaces of the bones they rest on. One meniscus rests on the medial tibial plateau; this is the medial meniscus. The other meniscus rests on the lateral tibial plateau; this is the lateral meniscus.[citation needed] These menisci act to distribute body weight across the knee joint. Without the menisci, the weight of the body would be unevenly applied to the bones in the legs (the femur and tibia). This uneven weight distribution would cause the development of abnormal excessive forces leading to early damage of the knee joint. The menisci also contribute to the stability of the joint.[citation needed] The menisci are nourished by small blood vessels but have a large area in the center with no direct blood supply (avascular). This presents a problem ...
There are two menisci in the knee. They sit between the thigh bone and the shin bone. While the ends of the thigh bone and the shin bone have a thin covering of soft hyaline cartilage, the menisci are made of tough fibrocartilage and conform to the surfaces of the bones they rest on. One meniscus rests on the medial tibial plateau; this is the medial meniscus. The other meniscus rests on the lateral tibial plateau; this is the lateral meniscus.[citation needed] These menisci act to distribute body weight across the knee joint. Without the menisci, the weight of the body would be unevenly applied to the bones in the legs (the femur and tibia). This uneven weight distribution would cause the development of abnormal excessive forces leading to early damage of the knee joint. The menisci also contribute to the stability of the joint.[citation needed] The menisci are nourished by small blood vessels but have a large area in the center with no direct blood supply (avascular). This presents a problem ...
Surgical removal of meniscal tissue can result in pain, loss of joint stability, dysfunction of mechanical forces and can lead to osteoarthritis and irreversible joint damage. Therefore, meniscus tissue should be preserved whenever possible. In case of massive loss of meniscus tissue there are two applicable methods for substitution: allograft transplantation or implant of a collagen meniscus scaffold. In 1992 Stone, Steadman and Rodkey have developed a bioreadsorbable collagen matrix (CMI) (Regen biologics, Inc.,Franklin Lakes NJ, USA) which acts as a scaffold to replace the original medial meniscus. This scaffold supports ingrowth of new tissue by means of migration of fibrochondrocytes and the production of extracellular matrix and should supports regeneration of meniscal like tissue. Between January 2001 to December 2003, 34 patients underwent arthroscopic placement of a collagen meniscus implant by a single surgeon to treat an irreparably damaged medial meniscus. In 6 cases the patients had ...
Meniscus tears are among the most common knee injuries. Athletes, particularly those who play contact sports, are at risk for meniscus tears. However, anyone at any age can tear a meniscus. When people talk about torn cartilage in the knee, they are usually referring to a torn meniscus.
The choice of type of surgery is based on the size and location of the tear, your age and activity level, the surgeons experience, and your preferences. Orthopedic surgeons most often perform meniscus surgery with arthroscopy, a procedure used to both examine and repair the inside of a joint. A thin tube (arthroscope) containing a camera and light is inserted through small incisions near the joint. Surgical instruments are inserted through other small incisions. Arthroscopic surgery may limit knee damage from surgery and may promote fuller recovery. But some tears may require open knee surgery.. In a total meniscectomy, the entire meniscus is removed. In a partial meniscectomy, the surgeon removes as little of the meniscus as possible. Unstable meniscal fragments are removed, and the remaining meniscus edges are smoothed so that there are no frayed ends. You may have general or regional anesthesia for a meniscectomy. Arthroscopic partial meniscectomy is commonly done in an outpatient surgical ...
Joint inflammation causes meniscus degeneration and can exacerbate post-traumatic meniscus injuries by extracellular matrix degradation, cellular de-differentiation and cell death. The aim of this study was to examine whether anti-inflammatory interleukin-10 exerts protective effects in an in vitro model of TNF-α-induced meniscus degeneration. Meniscus tissue was harvested from the knees of adult cows. After 24 h of equilibrium explants were simultaneously treated with bovine TNF-α and IL-10. After an incubation time of 72 h cell death was measured histomorphometrically (nuclear blebbing, NB) and release of glycosaminoglycans (GAG, DMMB assay) and nitric oxide (NO, Griess-reagent) were analysed. Transcription levels (mRNA) of matrix degrading enzymes, collagen type X (COL10A1) and nitric oxide synthetase 2 (NOS2) were measured by quantitative real time PCR. TNF-α-dependent formation of the aggrecanase-specific aggrecan neoepitope NITEGE was visualised by immunostaining. Differences between groups
Meniscal cysts are rare, Cyst of lateral meniscus 3 times to 10 times more common than cyst of medial meniscus.Etiology of meniscal cysts includes trauma which results in contusion and haemorrage within the substance of meniscus leading to mucoid degeneration, degeneration with age which results in local necrosis and mucoid degeneration into a cyst, developmental inclusion of synovial cells within the substance of the meniscus and often are a result of extrusion of synovial fluid through a tear of the meniscus,resulting in a one-way valve effect of the tear. Arthroscopic partial menisectomy followed by cyst decompression is currently recommended for treatment of ameniscal cyst.. We present a case of 18yr old female c/o pain and swelling in rt knee had h/o trauma 3 yrs back. O/e swelling 1×2 cm on medial tibial condyle, firm in consistency fixed to bone. Mri suggests grade 3 horizontal tear in posterior horn of medial meniscus and parameniscal cyst adjacent to medial meniscus.In this report, ...
This article will explore new research of that paints a fascinating picture of natural meniscus healing, surgical and non-surgical meniscus repair, and when Stem Cell Therapy (Bone Marrow Aspirate Concentrate) may or may not work for your meniscus tear. We will also discuss the role of comprehensive Prolotherapy in not only treating the meniscus but the articular knee cartilage as well. If you are considering meniscus surgery or already had meniscus surgery, this article will provide some good information in understanding your injury and what to expect from surgery and what to expect from stem cell Prolotherapy.
Dr Eric Strauss offers meniscus transplantation and knee meniscus replacement in New York. Treatment of a meniscal tear depends on its type and location of the tear.
TY - JOUR. T1 - Surgical and tissue engineering strategies for articular cartilage and meniscus repair. AU - Kwon, Heenam. AU - Brown, Wendy E.. AU - Lee, Cassandra A. AU - Wang, Dean. AU - Paschos, Nikolaos. AU - Hu, Jerry C.. AU - Athanasiou, Kyriacos A.. PY - 2019/1/1. Y1 - 2019/1/1. N2 - Injuries to articular cartilage and menisci can lead to cartilage degeneration that ultimately results in arthritis. Different forms of arthritis affect ~50 million people in the USA alone, and it is therefore crucial to identify methods that will halt or slow the progression to arthritis, starting with the initiating events of cartilage and meniscus defects. The surgical approaches in current use have a limited capacity for tissue regeneration and yield only short-term relief of symptoms. Tissue engineering approaches are emerging as alternatives to current surgical methods for cartilage and meniscus repair. Several cell-based and tissue-engineered products are currently in clinical trials for cartilage ...
To explore if medical exercise therapy (MET) alone is comparable to arthroscopic partial meniscectomy (APM) followed by MET for knee pain, activity level, and physical function in middle-aged patients with degenerative meniscal tear (DMT) by a systematic review and meta-analysis of randomized controlled trials (RCTs). A systematic search of electronic databases (PubMed, the Cochrane Library, Embase, and Web of Science) was conducted to retrieve RCTs comparing MET+APM with MET alone for DMT. Risk of bias of the studies was evaluated. Outcomes assessed were pain relief, physical function, and activity level. A total of 6 RCTs containing 879 patients were included. After pooling the data of 5 researches, we found small significant differences support the APM + MET group for pain control assessed by Knee injury and Osteoarthritis Outcome Score (KOOS) at 2 to 3 months (p = 0.004) and at 6 months (p = 0.04). And there were statistically improvements in APM + MET at 6 months compared with MET alone when
Treatment depends on the severity of the patients symptoms, physical exam findings, and finding on imaging studies. If the meniscus tear is not causing restriction of motion or significant mechanical type symptoms such as catching or locking, than typically a meniscus tear can be treated conservatively at first. This conservative treatment includes rest, ice, oral anti-inflammatory medication, cortisone injection and a home exercise program/physical therapy. If symptoms continue despite these conservative measures, surgery may be necessary. In the case of surgery, the meniscal tissue may be removed via arthroscopy (small poke hole incisions where a camera assists in the surgery) or it may be amenable to repair with stitches depending on the location of the tear, size of the tear and quality of the tissue. Meniscal repair is performed if it is felt that the meniscus has the ability to heal. Many meniscal tears occur in an area that has no ability to heal and therefore requires removal. This can ...
Meniscal transplantation (replacement or reconstruction) is gaining popularity in the treatment of patients under age 50 with early evidence of post-traumatic arthritis. At Cleveland Clinic, we reserve meniscal transplantation for minimally to moderately symptomatic patients with large, irreparable tears.. Meniscal injuries of the knee can occur at any age, but are most common in people age 30 to 50. Younger people tend to injure (tear) their meniscus in athletic endeavors, while older people sustain tears from minimal insults, such as twisting while getting out of a chair or golf cart.. The main function of the C-shaped cartilage is load transmission. The meniscus distributes forces between the femur and tibia over a larger surface area to reduce the point-contact forces of articular cartilage. They aid in joint lubrication and nutrition, and the medial (inner) meniscus acts as a "backup" stabilizer to the knee following anterior cruciate ligament (ACL) injury.. Because the majority of the ...
Novel Silk-based Scaffolds for Meniscus Tissue Engineering: The Relevance of Controlling Segmental Vascularization by Methacrylated Gellan gum ...
BACKGROUND: Partial meniscectomy dramatically increases the risk for post-traumatic, tibiofemoral osteoarthritis after anterior cruciate ligament reconstruction (ACLR). Concomitant medial meniscus surgery influences walking biomechanics (e.g., medial tibiofemoral joint loading) early after ACLR; whether medial meniscus surgery continues to influence walking biomechanics two years after ACLR is unknown. RESEARCH QUESTION: Does medial meniscus treatment at the time of ACLR influence walking biomechanics two years after surgery? METHODS: This is a secondary analysis of prospectively collected data from a clinical trial (NCT01773317). Fifty-six athletes (age 24â ¯±â ¯8 years) with operative reports, two-year biomechanical analyses, and no second injury prior to two-year testing participated after primary ACLR. Participants were classified by concomitant medial meniscal status: no medial meniscus involvement (nâ ¯=â ¯36), partial medial meniscectomy (nâ ¯=â ¯9), and medial meniscus ...
While Ben Roethlisberger serves his four-game suspension, the Steelers are down another quarterback after Dennis Dixon is expected to miss three to five weeks with a torn lateral meniscus in his left knee. The menisci are two cartilaginous discs located on the articulating surface of the lower leg bone known as the tibia. When the knee is violently twisted, the menisci are susceptible to injury and are easily pinched between bony protuberances located on the upper leg bone, the femur. The lateral meniscus sits on the outside portion of the knee with the medial meniscus located on the inside of the leg. The medical meniscus is C-shaped while the lateral meniscus is more O-shaped. The Steelers have yet to discuss surgery as an option and it remains an outside possibility that it can be avoided depending on the location of tear. Both menisci are broken into zones based on the amount of blood flow that is supplied to the area. The outer edges of the meniscus are well supplied with blood and known as ...
Meniscus repair, lateral and medial meniscus tear treatment, exercises, non-surgical treatment. Watch video testimonials of our patients.
Introduction. Cruciate disease is the most commonly operated orthopaedic disease in dogs and the main cause of stifle joint osteoarthritis (OA). Concurrent medial meniscal injury secondary to cruciate instability has been reported in 30-70% of cases1-5. Cruciate instability causes cranial tibial translation with relative caudal subluxation of the femoral condyles. The medial femoral condyle moves caudally on flexion and cranially on extension of the stifle joint causing shear stress primarily on the caudal pole of the medial meniscus. Lateral meniscal injuries are rare and the reported incidence ranges between 0-2% of all meniscal injuries.. Functional menisci improve congruency between the femoral condyles and the tibial plateau and provide critical roles in dissipation of compressive loads (shock absorption), stability, reduction in friction and protection of articular cartilage.. Loss of meniscal integrity impairs the ability of the meniscus to dissipate compressive forces transmitted ...
This website is a resource for patients and for surgeons and medical professionals to find out about Meniscal Transplantation.. Latest information, rehabilitation programs and centres undertaking the procedure are included in these pages.. To contact a surgeon performing Meniscal transplantation please use the map (CLICK HERE) and link to the surgeons website.. ...
U.S., April 4 -- ClinicalTrials.gov registry received information related to the study (NCT03097744) titled Predictors of Early Success From Circumferential Compression STITCH Meniscal Repairs on March 27. Brief Summary: This is a retrospective study of meniscal tear repairs at least one-year post repair status. All patients were treated with Ceterix NovoStitch devices. The primary objectives of this study are to assess the clinical repair success rate via reoperation and PROs at greater than 12 months. Study Start Date: Study Type: Observational Condition: Knee Medial Meniscus Tears Meniscus Lesion Meniscus; Rupture, Bucket Handle Meniscus Disorder Intervention: Device: Ceterix NovoStitch The device allows the physician to place a circumferential compression stitch around meniscal tears. This stitch is placed by passing suture from the tibial side to the femoral side of the meniscus and across the tear. This allows compression across the entire tear surface. Recruitment Status: Enrolling by ...
View our recommended knee braces for meniscus injuries. Prevent meniscus tears or provide support for your torn meniscus with a knee brace.
View our recommended knee braces for meniscus injuries. Prevent meniscus tears or provide support for your torn meniscus with a knee brace.
The fibrocartilaginous menisci dwell between the articular surfaces of the knee and play a central role in joint function. Damage through trauma or degenerative changes is a common orthopaedic injury, disrupts the meniscus mechanical function, and leads to the precocious development of osteoarthritis. The current standard of treatment is removal of the damaged tissue, a procedure that does not re-establish normal knee mechanics. Given the frequency of meniscal injury, a restorative repair strategy remains a major unmet need in orthopaedic medicine. With the goal of replacing damaged meniscus with engineered biologic tissue that can restore meniscal function, this work focuses on scaffolds composed of aligned biocompatible and biodegradable nanofibers that mimic the length-scale and organization of fibrous tissues. The highly ordered extracellular matrix of the meniscus is primarily composed of co-aligned collagen fibers, enabling the tissue to bear the high tensile loads seen with normal joint
This study is conducted as a collaboration between NAR, Orthopedic Department, Oslo University Hospital,Ullevaal, Hjelp24Nimi Oslo, Norway, and University of Southern Denmark, Odense, Denmark.. The investigators hypothesize that exercise is more effective than arthroscopic partial meniscectomy: a) on self-reported outcomes, functional performance and muscle strength in middle-aged patients subsequent to arthroscopic partial meniscectomy for a degenerative meniscus tear, and b) in preventing further development of knee osteoarthritis (OA). ...
What is a meniscus tear? A meniscus tear is a common knee injury. The meniscus is a rubbery, C-shaped disc that cushions your knee. Each knee has two menisci (plural of meniscus)-one at the outer edge of the knee and one at the inner edge. The menisci keep your knee steady by balancing your weight across the knee. A...
Meniscus tears are very common. Surgery to remove the torn part of the meniscus is also very common. Unfortunately, many people who have torn their meniscus…
Meniscus tears are very common. Surgery to remove the torn part of the meniscus is also very common. Unfortunately, many people who have torn their meniscus…
Reference: N Engl J Med 2013 Mar 18 early online, (level 2 [mid-level] evidence). Meniscal tears are common in patients with osteoarthritis of the knee, and symptomatic tears are frequently treated with arthroscopic surgery. Existing data from randomized trials show arthroscopic debridement is not effective for treating knee osteoarthritis (N Engl J Med 2008 Sep 11;359(11):1097, N Engl J Med 2002 Jul 11;347(2):81), but these trials have not specifically addressed meniscal tears. A new trial compared initial physical therapy vs. initial arthroscopic surgery for symptomatic meniscal tears in this population.. A total of 351 patients with mild-to-moderate osteoarthritis and symptomatic meniscal tear were randomized to 1 of 2 treatments and followed for 1 year. The first group began treatment with a standardized physical therapy regimen but had the option for surgery at the discretion of patient and surgeon. The second group had immediate arthroscopic partial meniscectomy followed by the same ...
A knee meniscus injury occurs when there is damage to the knee cartilage, usually from twisting awkwardly or from wear and tear. Here we look at meniscus tear symptoms and the causes, diagnosis and treatment options for the different types of meniscus injury.
It has been shown in cadaver models that tears in the medial meniscus posterior root causes increased contact pressures and kinematic derangements. However, meniscal repairs of these tears may restore the pressure to normal. Though tear repair may be successful in young patients, it may not be possible in a degenerated knee due to low healing potential wherein meniscal degeneration has already set in [4, 5]. Hence, partial meniscectomy has been proposed in this subset of patients to relieve mechanical symptoms [3-5]. Partial meniscectomy provides partial symptomatic relief in most cases, though the arthritic pain persists and does not arrest progression of radiographic osteoarthritis [3-5]. In our study, supervised physical therapy followed by a home-based program resulted in symptomatic and functional improvement over a short-term follow-up. Exercise as a treatment option after meniscal posterior root tears has not been sufficiently studied. Resistance training has been effective in ...
The average recovery time following a medial meniscus repair is approximately one month, but the exact recovery time depends on the individual patient and the severity of the tear, notes MedicineNet....
Recovery from an arthroscopy to remove the torn meniscus is relatively short. It is a minimally invasive outpatient surgery with typically 2 to 3 small puncture wounds to perform the surgery. The patient will typically be weight bearing as tolerated, but he/she may need to use crutches for a few days following the surgery. Swelling typically improves during the first week. Patients with sedentary jobs can return within one to two days. More physical laborers may take longer to recover. Patients typically return to sports or exercise by 4 to 6 weeks following a short period of physical therapy. Future blogs will describe meniscus repair and review the research we are currently involved with at Washington University Sports Medicine regarding meniscus repair ...
Across species, the avascular portion of the knee meniscus cannot heal spontaneously if severely injured. The most common treatment is meniscectomy which results in osteoarthritis. The objective of this study was to assess the fibrochondrogenic potential of equine fibroblast-like synoviocytes (FLS) seeded on scaffolds under the influence of growth factors in vitro to determine the potential of developing a novel cell-based repair strategy. Cultured FLS were seeded onto synthetic scaffolds in a rotating bioreactor under the influence of three growth factor regimens: none, basic fibroblast growth factor (bFGF) alone, and bFGF plus transforming growth factor (TGF-beta(1)) and insulin-like growth factor (IGF-1). Constructs were analyzed for mRNA expression and production of fibrochondroid extracellular matrix constituents. Type II collagen and aggrecan mRNA were significantly higher in growth factor-treated groups (p,0.05). Despite sub-optimal extracellular matrix production, FLS can exhibit ...
A tear of the posterior horn of medial meniscus refers to a meniscus tear in the back and inner side of the knee, explains Howard J. Luks, MD. The meniscus is a cartilage disk that acts as a shock...
Accurately depicts chondromalacia of the left medial femoral condyle with arthroscopic meniscus surgery. Shows the knee joint with extensive chondromalacia of the medial femoral condyle and a tear in the posterior horn of the medial meniscus. Surgical steps: 1. Inserting arthroscopic instruments into the knee joint through two stab wounds; 2. Removing unstable meniscal fragments; and 3. Post-operative condition showing the articular and meniscal cartilage debrided back to healthy tissue.
An important distinguishing feature of the knee is the presence of two menisci within the joint. These are two half moon shaped wedges of fibrous and cartilaginous material, which sit in the slightly hollowed surfaces of the tibia. They are at their thinnest in the middle and are fused to the joint capsule around their edges. The surfaces of these menisci are in direct contact with the cartilage of the joint. In fact, most people mistakenly call the menisci cartilage and in truth there are similarities in their respective structures. The menisci are not completely fixed inside the joint but their movement is limited. The menisci are supplied with nerves but not blood vessels. When a meniscus is torn there will be pain but no bleeding and more importantly, no healing. There may be some regeneration of damaged meniscus tissue at the site of the attachment to the joint capsule (where there are blood vessels) but otherwise a torn meniscus will not repair itself.. Knee Movement. Movement of the knee ...
Post-traumatic osteoarthrosis develops after intraarticular injuries. It is a disease, which affects both articular cartilage and subchondral bone, and progresses over 10-20 years. Irreversible damage has often occurred by the time clinical diagnosis is possible. More knowledge about the early phase of the disease might yield measures to detect and delay or even prevent progression. This thesis evaluates changes in articular cartilage and subchondral bone at an early stage of post-traumatic osteoarthrosis.. Simultaneous changes in articular cartilage and subchondral bone were evaluated 3 to 40 weeks post-operatively in a rabbit meniscectomy model for post-traumatic osteoarthrosis. Rabbits were meniscectomized in the right knee and sham-operated in the left knee. Osteoarthrotic cartilage changes were evaluated by histology. Changes in the subchondral bone were evaluated by histology, scintimetry and dual-energy X-ray absorptiometry (DEXA). Joint space narrowing, and its utility as diagnostic tool ...
The purpose of the study is to assess the added value of thin-cut (1 mm) axial magnetic resonance (MR) fat-saturated proton density (FS PD) weighted images (WIs) in the diagnosis of different types of meniscal tears. The study was conducted between January 2016 and August 2017 at a major private center group. This study included 28 patients with clinical suspicion of meniscal tear of age between 30 and 48 years including 19 males and 9 females. Axial 1-mm FS PD WIs were performed in addition to the conventional MR sequences. The type and classification of the meniscal tear were then diagnosed by a group of highly experienced musculoskeletal radiologists. The group assessed the morphology and classification of tears. The diagnosis was then confirmed by arthroscopy as a gold-standard reference. Meniscal tears were found in 23 out of 28 patients. Twenty-seven meniscal tears were found in the 23 patients: 2 root attachment radial tears (6.9%), 8 radial tears (27.6%), 7 longitudinal [vertical] tears (24%), 3
Background: Total meniscectomy leads to knee osteoarthritis in the long term. The poly(epsilon-caprolactone) (PCL) scaffold is a promising material for meniscal tissue regeneration, but cell-free scaffolds result in relatively poor tissue regeneration and lead to joint degeneration. Hypothesis: A novel, 3-dimensional (3D)-printed PCL scaffold augmented with mesenchymal stem cells (MSCs) would offer benefits in meniscal regeneration and cartilage protection. Study Design: Controlled laboratory study. Methods: PCL meniscal scaffolds were 3D printed and seeded with bone marrow-derived MSCs. Seventy-two New Zealand White rabbits were included and were divided into 4 groups: cell-seeded scaffold, cell-free scaffold, sham operation, and total meniscectomy alone. The regeneration of the implanted tissue and the degeneration of articular cartilage were assessed by gross and microscopic (histological and scanning electron microscope) analysis at 12 and 24 weeks postoperatively. The mechanical properties of
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OBJECTIVE: To discuss the advantages of the arthroscopic treatment for complex tears of the medial meniscus posterior horn by creating a tunnel passageway through the intercondylar fossa. METHODS: All 127 patients including 24 males and 103 females with complex tears at the medial meniscus posterior horn were reviewed. The age of all patients ranged from 45 to 78 years old, with an average of 67 years old. All 127 patients were treated with partial meniscectomy, in which 112 patients were treated with partial meniscectomy smoothly with three incisions (anterior medial incision, anterior lateral incision, high anterior lateral incision), and 15 patients were treated with four incisions (anterior medial incision, anterior lateral incision, high anterior lateral incision, posterior medial incision ...
With this objective in mind, we searched for to ascertain how reliably the diagnosis of BE could be concluded based upon obtaining ICD-9-CM code 530. a couple of in a patients medical records. The ICD-9-CM program code used for Barretts wind pipe (BE), 530. 2, will be also utilized for "ulcer regarding the esophagus" and therefore may possibly not be appropriate for identifying cases of Barretts esophagus for research purposes.. M23. 52 Long-term instability of knee (Posterior cruciate ligament or Posterior horn of medial meniscus) six M23. 51 Persistent instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus) 148 M23. 33 Other meniscus derangements (Medial security ligament or Other in addition to unspecified medial meniscus) 1311 M23. 27 Derangement of meniscus due to aged tear or injury-Capsular 3 M23. 25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus) 314. Esophageal manometric in addition to impedance studies - stress ...