J Neuroinflammation. 2017 Aug 4;14(1):156. doi: 10.1186/s12974-017-0930-6.. Brain-derived neurotrophic factor reduces inflammation and hippocampal apoptosis in experimental Streptococcus pneumoniae meningitis.. Xu D1, Lian D1, Wu J1, Liu Y2, Zhu M3, Sun J3, He D1, Li L4.. Author information. Abstract. BACKGROUND:. Streptococcus pneumoniae meningitis is a serious inflammatory disease of the central nervous system (CNS) and is associated with high morbidity and mortality rates. The inflammatory processes initiated by recognition of bacterial components contribute to apoptosis in the hippocampal dentate gyrus. Brain-derived neurotrophic factor (BDNF) has long been recommended for the treatment of CNS diseases due to its powerful neuro-survival properties, as well as its recently reported anti-inflammatory and anti-apoptotic effects in vitro and in vivo.. METHODS:. In this study, we investigated the effects of BDNF-related signaling on the inflammatory response and hippocampal apoptosis in ...
Method for Inducing Experimental Pneumococcal Meningitis in Outbred Mice. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Meningitis PPT: Very inoformative and Educative Powerpoint presentation on Airway management. In this powerpoint presentation on Neonatal Meningitis ppt, Pneumococcal Meningitis ppt, Acute Bacterial Meningitis ppt.
With an annual incidence of between 45 to 145 cases/100 000 population of children younger than 2 years old, S pneumoniae is the most common cause of invasive bacterial infection in children.40,,41 Pneumococcal meningitis continues to be a major cause of morbidity and mortality in both children and adults despite prompt diagnosis, effective antibiotic therapy, and intensive supportive care.1-10 Since the introduction of the protein-conjugated Hib vaccines in 1989 and the dramatic decline in the incidence of Hib meningitis,42-44S pneumoniae has become the most common cause of bacterial meningitis in children 1 to 23 months of age in the United States.10 Until several years ago, all isolates of S pneumoniae were considered susceptible to penicillin; penicillin was the antibiotic of choice for the treatment of serious pneumococcal infections, including meningitis. Reports of treatment failures in children with meningitis attributable to S pneumoniae with decreased susceptibility to penicillin and ...
Bacterial meningitis is an infection of the central nervous system characterized by a strong inflammation of the meninges and the subarachnoid space. Pneumococcal meningitis in humans is associated with long-term sequelae including sensory-motor deficits, seizures, and impairments of learning and memory. In order to evaluate this in an animal model, Streptococcus pneumoniae was cultured overnight in Todd Hewitt broth, diluted in fresh medium and grown to logarithmic phase, washed and resuspended in sterile normal saline 5 × 109 cfu/ml. Meningitis was induced by inoculating 10 μL of the S. pneumoniae suspension into the cisterna magna of the animals (rats, 60 days old, weighing 250-300 g) after removal of 10 μL of cerebrospinal fluid (CSF). All surgical procedures and bacteria administrations were performed under anesthesia. Meningitis was documented by a quantitative culture of 5 μl of CSF obtained by puncture of the cisterna magna at 8 h and 16 h after infection followed by the initiation ...
Background Empiric treatment of pneumococcal meningitis includes ceftriaxone with vancomycin to overcome ceftriaxone resistant disease. The addition of vancomycin bears a risk of adverse events, including increased antibiotic resistance. We assessed antibiotic resistance rates in pneumococcal meningitis before and after pneumococcal conjugate vaccine (PCV) implementation. Methods All pneumococcal meningitis episodes in children aged 5 years and younger, from 2004 to 2016, were extracted from the nationwide bacteremia and meningitis surveillance database. For comparison purposes, we defined pre-PCV period as 2004-2008 and PCV13 period as 2014-2016. Minimal inhibitory concentration (MIC) > 0.06 and > 0.5 μg/mL were defined as penicillin and ceftriaxone resistance, respectively. Results Overall, 325 episodes were identified. Pneumococcal meningitis incidence rates declined non-significantly by 17%, comparing PCV13 and pre-PCV periods. Throughout the study, 90% of isolates were tested for
|jats:title|Abstract|/jats:title||jats:p||jats:italic|Streptococcus pneumoniae|/jats:italic| is a common nasopharyngeal colonizer, but can also cause life-threatening invasive diseases such as empyema, bacteremia and meningitis. Genetic variation of host and pathogen is known to play a role in invasive pneumococcal disease, though to what extent is unknown. In a genome-wide association study of human and pathogen we show that human variation explains almost half of variation in susceptibility to pneumococcal meningitis and one-third of variation in severity, and identified variants in |jats:italic|CCDC33|/jats:italic| associated with susceptibility. Pneumococcal variation explained a large amount of invasive potential, but serotype explained only half of this variation. Newly developed methods identified pneumococcal genes involved in invasiveness including |jats:italic|pspC|/jats:italic| and |jats:italic|zmpD|/jats:italic|, and allowed a human-bacteria interaction analysis, finding associations between
In this case, the occurrence of three episodes of pneumococcal meningitis over a 4-year period highlights the controversial efficacy of vaccination and antibiotic prophylaxis in HIV-1-infected patients. Recurrent meningitis is a rare disease that is often associated with cranial injuries, and S. pneumoniae is responsible for more than half of the recurrent purulent bacterial meningoencephalitis [10]. The first episode was probably due to the bilateral maxillary sinusitis, as was already reported [11]. Furthermore, the infection with HIV-1 and the splenectomy were also shown to be additional risk factors [12-14, 7]. However, at the time of anti-pneumococcal vaccination and before the third episode occurred, the patient had CD4+ cell count greater than 500 cells/μl, which was reported to decrease the risk of pneumococcal disease [7].. The patient was not receiving anti-pneumococcal chemoprophylaxis when the first and second episodes occurred. However, when the third episode occurred, the patient ...
The aim of this study is to determine the prevalence of pneumococcal meningitis in the paediatric population in Spain four years after the marketing of Prevenar. Also secondary objectives are: 1) to determine the clinical characteristics and outcome of the disease; and 2) to determine serotypes and antibiotic resistance patterns ...
Despite numerous recent optimistic reports concerning the rate of cure in pneumococcal meningitis, a review of 22 adult cases observed at the Morrisania City Hospital from 1943 through June, 1951, resulted in a more pessimistic and guarded prognosis. Although the almost 100 per cent mortality of this disease in the presulfonamide era is well documented, it is of particular interest to note that the cases herein presented were all treated with combined penicillin and sulfonamides. Despite this, 15 patients died, leaving a gross mortality rate of approximately 70 per cent, which is in sharp contrast to a 73 per cent ...
Background Delayed cerebral thrombosis (DCT) is a devastating cerebrovascular complication in patients with excellent initial recovery of pneumococcal meningitis. The aetiology is unknown, but direct...
Abstract Streptococcus pneumoniae (pneumococcal) meningitis is a common bacterial infection of the brain. The cholesterol-dependent cytolysin pneumolysin represents a key factor, determining the neuropathogenic potential of the pneumococci. Here, we demonstrate selective synaptic loss within the superficial layers of the frontal neocortex of post-mortem brain samples from individuals with pneumococcal meningitis. A similar effect was observed in mice with pneumococcal meningitis only when the bacteria expressed the pore-forming cholesterol-dependent cytolysin pneumolysin. Exposure of acute mouse brain slices to only pore-competent pneumolysin at disease-relevant, non-lytic concentrations caused permanent dendritic swelling, dendritic spine elimination and synaptic loss. The NMDA glutamate receptor antagonists MK801 and D-AP5 reduced this pathology. Pneumolysin increased glutamate levels within the mouse brain slices. In mouse astrocytes, pneumolysin initiated the release of glutamate in a ...
J Interferon Cytokine Res. 2015 Sep 29. [Epub ahead of print]. Interferon-γ-Induced Nitric Oxide Synthase-2 Contributes to Blood/Brain Barrier Dysfunction and Acute Mortality in Experimental Streptococcus pneumoniaeMeningitis.. Yau B1, Mitchell AJ1,2, Too LK1, Ball HJ1, Hunt NH1.. Author information. Abstract. The proinflammatory cytokine interferon-gamma (IFNγ) recently was shown to play a crucial role in experimental pneumococcal meningitis (PM) pathogenesis, and we aimed in this study to investigate IFNγ-driven nitric oxide synthase-2 (NOS2)-mediated pathogenesis of murine PM. We demonstrate that costimulation of toll-like receptors and IFNγ receptors was synergistic for NOS2 expression in cultured murine microglia. Using an experimental PM model, wild-type mice treated with anti-IFNγ antibody, as well as IFNγ and NOS2 gene knockout (GKO) mice, were inoculated intracerebroventricularly with 103 colony-forming units of Streptococcus pneumoniae (WU2 strain). Mice were monitored daily ...
The implementation of pneumococal conjugate vaccines (PCVs) 7 then 13 valent (Prevenar13®) in 2010-2011 has significantly changed the profile of pneumococcal meningitis. Since 3 years, the National Pediatric Meningitis Network of the Pediatric Infectious Disease Group (GPIP) and the National Reference Centre of Pneumococci have reported no cases of meningitis due to pneumococcus resistant to third-generation cephalosporins (3GC): cefotaxime or ceftriaxone. In the light of these new data, vancomycin should no longer be prescribed at the initial phase of pneumococcal meningitis treatment (confirmed or only suspected) and this antibiotic should only be added when 3GC minimum inhibitory concentration of the strain isolated is greater than 0 ...
Despite sufficient antibiotic treatment, pneumococcal meningitis has remained a disease associated with high mortality and neurological sequelae. The disruption of the blood brain barrier (BBB) is regarded a key event in the initial phase of pneumococcal meningitis. However, the exact molecular mechanisms involved in this process are still unknown. The aim of this study was to determine if living pneumococci are able to induce apoptosis in cerebral endothelial cells - the main cellular component of BBB - and therefore might contribute to its damage. Using several different detection methods (TUNEL, fluorescence and electron microscopy), induction of apoptotic cell death of endothelial cells by pneumococci could be verified. An accompanying activation of caspases was not detectable, despite the use of specific detection techniques such as inhibition experiments, direct enzyme measurements and detection of caspase-specific protein cleavage. These results as well as the specific nuclear morphology ...
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Free, official coding info for 2018 ICD-10-CM G00.1 - includes detailed rules, notes, synonyms, ICD-9-CM conversion, index and annotation crosswalks, DRG grouping and more.
I became involved and aware of Meningitis Now through my youngest daughter, Eliza, having contracted pneumococcal meningitis and septicaemia in 2007.
The study compares the incidence and serotype distribution of invasive pneumococcal disease (IPD) for pneumococcal meningitis and non-meningitis IPD in children from 2007 to 2010 with reference to the pre-vaccination period from 1997 to 2001 in Germany.. ...
The study compares the incidence and serotype distribution of invasive pneumococcal disease (IPD) for pneumococcal meningitis and non-meningitis IPD in children from 2007 to 2010 with reference to the pre-vaccination period from 1997 to 2001 in Germany.. ...
Pneumococcus can be found as commensal (normal) flora in up to 40% of the population and is the most common cause of meningitis in adults and in children over the age of two. The organism may reside in the back of the throat and in the nose where it can be passed on to others through close physical contact such as kissing or through coughs and sneezes. If the opportunity presents itself, this opportunist may invade the body to cause serious infections such as bacteraemia or meningitis. Still rather rare pneumococcal meningitis occurs at a rate of about 2 in every 100,000 of the Canadian population (1) ...
Among the minority of piliated cocci in the brain showing a division septum, we could distinguish bacteria in the early and late stages of cell division by high-resolution microscopy (Supplemental Figure 12, A and B). Even though most single cocci did not express DivIVA in the brain, bacteria caught in the division process were DivIVA positive. In particular, at the early stages of cell division, when bacteria had a round shape, with the formation of a division septum, DivIVA was expressed at the poles of the cells (Supplemental Figure 12A). During cell division, the bacterial cell was more elongated and more closely resembled a diplococcus with 2 nearly formed daughter cells. At this stage, the DivIVA signal was severely decreased (Supplemental Figure 12B). These findings strongly suggest that the DivIVA protein is not always absent in piliated bacteria during brain invasion but is instead present for only a limited time while single cocci are dividing. This very limited expression of DivIVA ...
We conducted a retrospective analysis of 55 community-acquired Streptococcus pneumoniae meningitis illnesses in Huntington, West Virginia, from 1978 to 1997. Fourteen (36.8%) of 38 adults and 2 (11.8%) of 17 children died. Serotypes 6, 23, 3, and 18 accounted for 20 (41.7%) of 48 strains available for serotyping. Of 40 strains available for antimicrobial susceptibility testing, 1 serotype 19 and 1 serotype 23 strain showed intermediate resistance and a second serotype 23 strain showed high resistance to penicillin; all three patients survived. The case-fatality rates among adults who received penicillin alone, gentamicin in combination, or vancomycin and cephalosporin together were 57.1%, 55.5%, and 60%, respectively, and among those who received chloramphenicol or a third-generation cephalosporin, they were 11.1% or nil, respectively. No child died who received chloramphenicol or vancomycin. Two (33%) of 6 children died who received a third-generation cephalosporin; both were critically ill ...
The treatment is called dexamethasone.. "Using this treatment in people infected with meningitis has been under debate because in a few large studies it was shown to be ineffective," said study author Diederik van de Beek, MD, PhD, with the Academic Medical Center, University of Amsterdam in the Netherlands and a member of the American Academy of Neurology. "Our results provide valuable evidence suggesting that dexamethasone is effective in adult cases of bacterial meningitis and should continue to be used.". Bacterial meningitis is a condition that causes membranes in the brain and spinal cord to become inflamed. The disease can be deadly, or result in hearing loss, brain damage and learning disabilities. Pneumococcal meningitis is the most common and severe form of bacterial meningitis. It is estimated that about 25 to 30 percent of people die from the disease.. For the study, researchers evaluated 357 Dutch people age 16 or older with pneumococcal meningitis between 2006 and 2009. Of those, ...
The Particulars: Studies have indicated that meningitis vaccinations can help reduce the number of cases of the most common meningeal pathogens. Researchers, however, have not explored the patterns of the most common bacterial etiologies in the United States.. Data Breakdown: A review of national hospital discharge data on bacterial meningitis found that Streptococcus pneumoniae appeared to be the most common cause of bacterial meningitis between 1997 and 2010 . During the study period, the incidence of pneumococcal meningitis decreased by 63%. Mortality from S. pneumoniae meningitis decreased by 68% in the study. The number of Neisseria meningitides cases also decreased by 86%. The average hospital lengths of stay (LOS) for patients with bacterial meningitis did not appear to change significantly. However, the average costs for hospitalization increased from $30,000 to $70,000 over the 13-year study period.. Take Home Pearls: Streptococcus pneumoniae appears to be the leading cause of bacterial ...
Before the study of de Gans and van de Beek, only 3 randomised trials evaluated dexamethasone in adults with bacterial meningitis. The first,1 done in Egypt, showed a survival benefit in a subset of adults with pneumococcal meningitis. However, 60% of the patients were comatose at entry, and antibiotics were administered intramuscularly. The second study,2 which showed a trend to better outcomes with dexamethasone, enrolled only 60 patients of a planned 256, and dexamethasone could be administered up to 3 hours after the first dose of antibiotics. The third study,3 done in India, enrolled only 30 patients, and dexamethasone was started after antibiotics.. The study by de Gans and van de Beek addresses the limitations of the previous studies. The sample size was 301, and dexamethasone was given before or at the same time as the first antibiotic dose. The benefit of dexamethasone was largely restricted to those with pneumococcal meningitis.. The study was done principally in the Netherlands, where ...
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Streptococcus pneumoniae is the leading cause of bacterial meningitis. Pneumococcal meningitis is a life-threatening disease with high rates of mortality and neurological sequelae. Immune targeting of S. pneumoniae is essential for clearance of infection; however, within the brain, the induced infla …
TY - JOUR. T1 - Management of acute bacterial meningitis.. AU - Obaro, S. K.. PY - 1996/2/24. Y1 - 1996/2/24. UR - http://www.scopus.com/inward/record.url?scp=16144367466&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=16144367466&partnerID=8YFLogxK. M3 - Comment/debate. C2 - 8596282. AN - SCOPUS:16144367466. VL - 347. SP - 538. JO - The Lancet. JF - The Lancet. SN - 0140-6736. IS - 9000. ER - ...
The childhood vaccinations are given in rapid succession at two, three and four months to protect small babies from whooping cough, diphtheria, tetanus, polio, haemophilus Meningitis(HIB), pneumococcal Meningitis and Meningitis C. There are very few reasons for not vaccinating a child. If you are concerned that your child should not have a vaccination on a particular day, perhaps because they are unwell, please bring them to the surgery so that the doctor can assess whether or not to administer the vaccination. It is very rare for a child to be unable to have the whooping cough vaccinations. We would withhold the whooping cough vaccine only if a child had had previous bad reaction to this vaccine. Please note that epilepsy, asthma and prematurity are not medical reasons for withholding the jab. There is a very real danger of your baby suffering severe chest problems and possible epilepsy if the whooping cough illness is contracted in the first year of life through not being vaccinated. Over ...
p]Thanks for coming to my fundraising page. [/p][p]My cousin, John Mathews, had recently retired from a long and distinguished career as a rheumatologist at St Thomas Hospital in London and went on a trip around South East Asia with his wife, Wendy. When he returned he didnt feel quite right and had some unusual symptoms. He rapidly deteriorated and almost two years ago to the day of the Marathon, John died of pneumococcal meningitis.[/p][p]Although initially having a place in last years race, alongside his daughter Cathy and son Colin, I had to defer my entry due to injury. This year Im fighting fit and training is going very well, despite a lot of on-calls, weekends at work and two young and tiring children![/p][p]Meningitis is still a devastating disease. Im currenlty working in infectious diseases and meningitis is seen in every hospital around the country - survival rates are improving but it still regularly kills or leaves survivors disfigured. Just a few weeks ago a 19 year old ...
Case Presentation: The patient was a 27 year-old man who was referred to the clinic following a few days of fever and cold with consciousness deficit and right hemiplegia. Based on the analysis of cerebrospinal fluid (CSF) and diagnosis of pneumococcal meningitis, he received suitable antibiotic treatment. Despite complete return of consciousness, good general condition, and negative smear and culture of CSF, fever continued and no considerable improvement was observed in the hemiplegia. Therefore, brain magnetic resonance imaging (MRI) was performed and according to the findings, treatment was started with the diagnosis of acute disseminated encephalomyelitis. Treatment with prednisolone at first obviated the fever and after a month brought about a complete hemiplegia cure. Following the status of the patient after three months, his MRI clearly showed considerable reduction in lesions. ...
Pneumococcal meningitis in an alcoholic patient. Head opened at autopsy revealing purulent inflammation of leptomeninges beneath reflected dura mater.. Image courtesy of: CDC/ Dr. Edwin P. Ewing, Jr. This image is in the public domain and thus free of any copyright restrictions. As a matter of courtesy we request that the content provider be credited and notified in any public or private usage of this image.Original file available through http://phil.cdc.gov/. ...
More than two weeks after the first reports emerged of meningitis cases linked to tainted painkiller injections, health officials at the Centers for Disease Control and Prevention (CDC) say the number of cases will continue to rise, since the infections may take weeks to appear.
問題回顧 我們回顧了在急性細菌性腦膜炎的成人與小孩族群中,皮質類固醇在其死亡率、聽力損失與神經系統後遺症的影響(像是聽力受損、神經缺陷)。. 背景 急性細菌性腦膜炎是種腦膜的感染(一種包覆腦與脊髓的膜狀系統),通常會造成聽力受損。儘管接受充足的抗生素治療,細菌性腦膜炎在 5% 到40%小孩與20%到50%成人是致命的。細菌感染通常是從耳部或呼吸道傳播,使用抗生素治療。. 皮質類固醇為能夠減少因感染引起發炎的藥物。在動物的腦膜炎試驗中指出,這種發炎會加劇神經系統的損傷。對於使用抗生素合併使用皮質類固醇的研究顯示出相互矛盾的結果。. 我們希望探討皮質類固醇的使用是否較使用安慰劑更好或更糟。. 研究性質 ...
Specimens from a child who died in Kotzebue this week are being studied at the Arctic Investigations Program, a branch of the Centers for Disease Control and Prevention in Anchorage.
TY - JOUR. T1 - Induction of labyrinthitis ossificans after pneumococcal meningitis. T2 - An animal model. AU - Brodie, H. A.. AU - Thompson, T. C.. AU - Vassilian, L.. AU - Lee, B. N.. PY - 1998. Y1 - 1998. N2 - Newly formed disorganized bone fills the open spaces within the otic capsule in various pathologic conditions, resulting in labyrinthitis ossificans. The pathologic mechanisms of this disease remain poorly understood. To better study the sequence of events and contributing mechanisms involved in labyrinthitis ossificans, an animal model was developed. Three groups of Mongolian gerbils received either an intralabyrinthine injection of normal saline solution (group 1) or Streptococcus pneumoniae polysaccharide capsule antigens (groups 2 and 3). The temporal bones were harvested after 3 months and serially sectioned. None of the eight control animals (group 1), which received intralabyrinthine injections of normal saline solution had any histologic changes in their temporal bones. Nine of ...
CNS infection is a life-threatening condition in developing countries and Streptococcus pneumoniae has been reported as the most common cause of bacterial meningitis; however, there is limited data on pneumococcal meningitis in Indonesia. This cross-sectional study aimed to isolate and identity S. pneumoniae strains from cerebrospinal fluid (CSF) specimens collected as part of routine testing from patients with clinically diagnosed central nervous system infection at a national referral hospital in Jakarta, Indonesia in 2017. S. pneumoniae isolation and identification were performed using conventional culture and molecular tools. Antibiotic susceptibility patterns were monitored through minimum inhibitory concentration testing. From 147 CSF specimens, one S. pneumoniae strain was identified from a patient with bacterial meningitis symptoms. The isolate was serotype 6B (ST5661) and susceptible to 18 antimicrobial agents tested, including penicillin, tetracycline, and the macrolide group. Our data
Bacterial Meningitis - Pipeline Insight, 2020 has complete details about market of Bacterial Meningitis industry, Bacterial Meningitis analysis and current trends. Bacterial Meningitis Overview "Bacterial Meningitis Pipeline Insight, 2020" Report By DelveInsight Outlays Comprehensive Insights Of Present Clinical Development Scenario And Growth Prospects Across The Bacterial Meningitis Market. A Detailed Picture Of The Bacterial Meningitis Pipeline Landscape Is Provided, Which Includes The Disease Overview A.
Most people recover with no after effects and not all after effects are permanent. The likelihood of getting after effects from meningitis or septicaemia depends on several factors including the type and severity of the illness. People who have been desperately ill may have spent a long time in intensive care. Research has shown that intensive care can be a distressing experience both for the person who has the illness and for their family.. Currently the majority of cases of bacterial meningitis and septicaemia are caused by meningococcal infection. This produces severely disabling after effects in about one in twelve survivors, although patients who have severe meningococcal septicaemia tend to have a worse outcome. After meningococcal disease, pneumococcal meningitis is the main type and it is more likely to produce serious damage. Neonatal meningitis occurring in the first month of life also carries a higher risk of after effects than most other forms.. A person recovering from viral ...
View Notes - BACTERIAL MENINGITIS PRESENTATION from RN 202 at Cazenovia College. BACTERIAL MENINGITIS What is it? Bacterial meningitis is a serious infection of the spinal cord and the fluid that
Microbiologic causes of meningitis include bacteria, viruses, fungi, and parasites. Before routine use of pneumococcal conjugate vaccine, bacterial meningitis affected almost 6000 people every year in the United States, and about half of all cases occurred in children 18 years old or younger. Prompt and accurate diagnosis and adequate treatment of bacterial meningitis in children remains a major challenge, as reflected by the continued high morbidity and case-fatality rates of the disease worldwide. Appropriate use of antibiotics, along with adjunctive therapies, such dexamethasone, has proved helpful in the prevention of neurologic sequelae in children with bacterial meningitis. Better understanding of pathophysiologic mechanisms likely would result in more effective therapies in the future.
Health officials in Volta Region have confirmed a first case of cerebrospinal meningitis, a disease common in the three regions of the north.. The Regional Directorate of the Ghana Health services has been deploying disease control officers to the Krachie West district where the case was recorded.. Disease surveillance is also being stepped up around the region, officials say.. Earlier reports from the region had suggested an outbreak of 7 new cases of pneumococcal meningitis which has so far claimed 33 lives in three regions - Brong Ahafo, Northern and Ashanti regions.. However, Regional Director of Ghana Health Services, Joseph Teye-Nuertey, told Joy News Kwabena Owusu-Ampratwum the reports were not accurate.. "The conditions in Krachie are just like in the north [of the country]. So if in the north you normally have such cases around this time of the year, then it is not out of place to have a case like this in Krachie West", he said.. He said the Ghana Health Service in the region has been ...
Meningitis Canada - researchers from the University of British Columbia, Vancouver reported in The Pediatric Infectious Disease Journal (March 2009 issue) that rates of meningitis decreased in Canadian provinces that introduced routine immunization of children and adolescents against one specific strain of meningococcal bacteria.. Meningitis USA - researchers from the University of Michigan Medical School carried out a national survey which found that the incidence of meningitis in the USA fell by 31% from 1998 to 2007 after the introduction of routine vaccinations against bacterial meningitis-causing bacteria.. Meningitis B vaccine approved in Europe - in January 2013, Bexsero was approved by the European Union to prevent life-threatening meningitis for humans aged at least two months. This is the first vaccine to prevent meningococcal serogroup B (Meningitis B).. Meningitis UK Founder, Steve Dayman MBE said "This meningitis B vaccine is the most important medical breakthrough in the 30 years ...
Bacterial meningitis can be a life-threatening infection especially in children where it is most common. While not as prevalent as its viral counterpart, it is still a significant source of morbidity and mortality worldwide. There are a number of organisms that can cause meningitis, and they vary depending on age . While the most common cause of bacterial meningitis overall is Streptococcus pneumoniae, in children, meningitis can be caused by Neisseria meningitidis and Haemophilus influenzae or a combination of organisms as well.. Another concern which rises with bacterial meningitis is the rise of treatment resistant organisms. Though this is an issue with any human infection, it is especially troublesome in meningitis due to the rapid sequelae of symptoms and residual effects on the brain after recovery.. Researchers at the University of Strathclyde and the University of Manchester have developed a rapid test to determine the specific bacterial etiology of bacterial etiology. The hope is to ...
Major changes in the epidemiological characteristics of bacterial meningitis have been observed as a result of changes in behaviour, human interventions (use of antibiotics, prophylactic vaccinations), as well as poorly elucidated mechanisms responsible for epidemic outbreaks.. The objective of this study is to identify the determinants of in-hospital mortality of bacterial meningitis in adults.. Hypothesis : the standardized data collection concerning cases of bacterial meningitis in adults with telephone follow-up would allow analysis of the determinants of mortality and neurosensory sequelae, description of the psychosocial impact and proposal of new treatment strategies. ...
How to Prevent Bacterial Meningitis - Brain infections like Bacterial Meningitis is a serious, and often fatal disease. Visit HowStuffWorks to learn how to prevent Bacterial Meningitis.
What does bacterial meningitis feel like - Why I s there "acute" bacterial meningitis? Is there such a thing as mild bacterial meningitis? No. Just like there is not a mild form of the black plague. A little poison is still poison.
vScience Bites Radio. small bites you can remember. to bite them in the behind. Meningitis B and the Meningitis B Vaccines, Part 2. Date: August 21, 2019. www.Courses4Mastery.com. [email protected] Text MVI to 555888 to join our email list. Recap Part 1. 1. The Illness. 2. The incidence of infection - rare!. 3. History of the vaccines - and current use. 4. The Push for College Students. Part 2: Meningitis Serotype B. Today, were going to discuss the two newest meningitis vaccines specifically for serogroup B: Trumenba and Bexsero.. Recall that the meningitis vaccines generate antibodies against four of the most common Neisseria meningitis serotypes that have been found to cause meningitis: A/C/Y/WI-135. However, the most common serotype showed to cause the infection about 52% of the time in the US and about 90% of the time in Europe is serotype B.. Why was serotype B not included in the original vaccines? Because the surface antigens on the serotype B bacteria cross-react with brain ...
Meningitis is a serious disease with flu like symptoms in the early stages.. Meningitis disease is usually caused by bacteria and viruses that exist in our bodies. Symptoms during the early stages of meningitis disease are often mistaken as the flu. The disease often follows on from a flu-like illness or infection. Meningitis has a variety of causes, including bacterial, viral and fungal infection, reactions to medications, weak immunity, and ecological toxins such as heavy metals. The most severe form of meningitis is bacterial. Meningitis can lead to brain swelling and cause permanent disability, brain damage, coma and even death in serious untreated cases. Therefore it is of utmost importance to learn the signs and symptoms of meningitis.. ...