TY - JOUR. T1 - Relationship of age, sex, and reproductive status to the quantity of tyrosine hydroxylase in the median eminence and superior cervical ganglion of the rat. AU - Porter, J. C.. PY - 1986. Y1 - 1986. N2 - Tyrosine hydroxylase (TH) in the median eminence (ME) and superior cervical ganglion (SCG) of the rat was quantified by means of an immunoblot procedure, using highly purified rat TH as the standard. Antibodies against rat TH were produced in the rabbit. The assay was linear from 0-100 ng TH and had a correlation coefficient of 0.990 ± 0.0014 (mean ± SE: n = 22). The interassay coefficient of variation was 8.65% (n = 17). In young female rats (12-16 weeks old) with regular 4-day estrous cycles, the quantity of TH in the ME on various days of the cycle was as follows: estrus, 42 ± 2.9 ng; diestrous day, 1, 61 ± 2.8 ng; diestrous day 2, 75 ± 4.2 ng; and proestrus, 84 ± 3.3 ng. In ovariectomized rats (15-16 weeks old), the ME contained 24 ± 1.6 ng TH. In prepubertal rats ...
The external layer of the lateral muscle wall in the neck occupies a posterior position in relation to its other lateral counterparts. The muscle, the posterior scalene, spans from the costal elements of the cervical vertebrae to the outer surface of the second rib ...
Using two different immunocytochemical approaches at the electron microscopic level, it was shown that substances related to enkephalin and somatostatin coexist in the same granules in the median eminence of the guinea-pig. This finding means that the two neuropeptides are simultaneously released. The possible inhibiting action of enkephalins on somatostatin release is discussed related to other data.
Hypothalamic tanycytes are highly specialised glia that interface with the fenestrated capillaries of the median eminence, hypothalamic neurons, and the cerebrospinal fluid of the 3rd ventricle, serving a vital role in the regulation of homeostatic control. Stereotypically, tanycytes are divided into four subsets which express an array of different markers. Recent studies show that tanycytes in adult mice include a subset of neurogenic stem/progenitor cells, though reports conflict when identifying which subset is neurogenic. Furthermore, most reports focus on tanycytes in the medial hypothalamus, but do not discuss how their findings relate to tanycytes of anterior and posterior hypothalamic subregions. In this study I characterise a variety of established tanycyte markers across the anterior-posterior axis of the hypothalamus, describe the cell adhesion molecule NrCAM as a new tanycyte marker, and show, for the first time, Sonic Hedgehog (Shh) expression in a tanycyte subset around the adult ...
The present invention generally pertains to multilayer film comprising four or more discrete layers. The films contain two external layers, an internal stiffening layer and an internal shrink layer. The external layers comprise linear low density polyethylene resin, the stiffening layer comprises polypropylene or a high density polyethylene and the shrink layer comprises low density polyethylene. The multilayer films of the present invention are characterized by having a gloss of at least 62% at 45 degrees, together with a 2% secant tensile modulus greater than 400 MPa.
schwit1 quotes a report from Indy100: A team of scientists from Massachusetts General Hospital and Harvard Medical School have used adult skin cells to regenerate functional human heart tissue. The study, published in the journal Circulation Research, detailed that the team took adult skin cells, u...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Hypothalamic CRH neurons that control ACTH secretion from the pituitary gland have secretory terminals in the external zone of the median eminence (ZEME). These neurons can coproduce vasopressin (AVP), a neuropeptide that potentiates the ACTH releasing effects of CRH. Recently, we found increased AVP production in adult rats weeks after single exposure to a stressor, which may play a role in event-induced stress disorders. Here, we describe the long-term changes in the HPA axis of adult male rats following a single exposure to a stressor, the cytokine interleukin-1 beta (IL-1 beta). The effects on storage and release of AVP and CRH were established by quantitative immunocytochemistry, the effects on ACTH and corticosterone responses by radioimmunoassay. Single administration of IL-1 beta (5 micrograms/kg i.p.) induces a delayed (at least 4 d) and a long-lasting (at least 3 weeks) increase of vasopressin (AVP) stores in CRH terminals of the ZEME without affecting the CRH stores, and a marked ...
In the adult brain, well-characterized neurogenic niches are located in the subventricular zone (SVZ) of the lateral ventricles and in the subgranular zone (SGZ) of the hippocampus. In both regions, neural precursor cells (NPCs) share markers of embryonic radial glia and astroglial cells, and in vitro clonal expansion of these cells leads to neurosphere formation. It has also been more recently demonstrated that neurogenesis occurs in the adult hypothalamus, a brain structure that integrates peripheral signals to control energy balance and dietary intake. The NPCs of this region, termed tanycytes, are ependymal-glial cells, which comprise the walls of the infundibular recess of the third ventricle and contact the median eminence. Thus, tanycytes are in a privileged position to detect hormonal, nutritional and mitogenic signals. Recent studies reveal that in response to nutritional signals, tanycytes are capable of differentiating into orexigenic or anorexigenic neurons, suggesting that these cells are
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Most of our knowledge on the mechanisms of thyroid hormone (TH) dependent brain development is based on clinical observations and animal studies of maternal/fetal hypothyroidism. THs play an essential role in brain development and hormone deficiency during critical phases in fetal life may lead to severe and permanent brain damage. Maternal hypothyroidism is considered the most common cause of fetal TH deficiency, but the problem may also arise in the fetus. In the case of congenital hypothyroidism due to defects in fetal thyroid gland development or hormone synthesis, clinical symptoms at birth are often mild as a result of compensatory maternal TH supply. TH transporters (THTs) and deiodinases (Ds) are important regulators of intracellular triiodothyronine (T3) availability and therefore contribute to the control of thyroid receptors (TRs)-dependent CNS development and early embryonic life. Defects in fetal THTs or Ds may have more impact on fetal brain since they can result in intracellular T3
Summary of Facts and Submissions. I. European patent No. 1 594 478 was granted on the basis of ten claims.. Independent claim 1 reads as follows:. 1. Tablets containing one or more active pharmaceutical, dietetic or nutritional ingredients comprising at least one inner layer of gum base and outer layers comprising antiadhesion excipients and compression adjuvants selected from Isomalt, Maltol, Maltodextrin, Maltitol, Mannitol, Xylitol, Lactitol, Lactose, Skim Milk, Eritritol, Oligofructose, Retrograded Starch, polysorbates, polyethyleneoxide, dextrans, Cyclodextrins, Oligosaccarose, fructose, hydrogenated starch hydrosilates, said tablets having a sandwich like structure, the external layers containing said antiadhesion excipients being not in contact one with the other and respectively coating only the upper and the bottom part of the gum core, leaving the peripheral side thereof uncoated.. Claims 2 to 8 are dependent on claim 1. Independent claim 9 is directed to a process for the ...
evident in Alcyonella and Plumatella towards the fundus of the stomach; they become less distinct as we ascend toward the oesophagus, and totally disappear from this tube and from the rectum. The fundus of the stomach appears to differ from the rest of the alimentary canal in structure and function; the well-defined longitudinal rugae and deep brown colour of the internal layer of the stomach nearly disappear in it, and, during the process of digestion, we may perceive that the peculiar peristaltic action of the walls is more marked in it than in any other part of the gastric cavity, while it is every now and then separated from the rest of this cavity by a momentary hour-glass constriction. In the oesophagus there are only two layers (Pl. III, fig. 7, X′, u). These correspond to the middle and external layers of the stomach, the former being here largely developed (A), while the internal or hepatic layer of the stomach is entirely absent, and there are no longitudinal rugae. The mouth and ...
Genus Pseudoraphidiophrys Mikrjukov, 1997. Diagnosis: Centroheliozoa with a periplast comprising 2 types of tangential scales: the internal layer plate-scales without a hollow marginal rim, and an external layer of plates with a well developed sternum and radiating ribs. The base of the sternum may be expanded and concave to create a velum-like extension of the scale. No records from light microscopy ...
Sulfonamide bacteriostatic antibiotic or "Sulfamethoxazole" (sul-fa-me-thak-se-zol), the main component in Septran, is absolutely one of a class of medications known as antibiotics, which capture the development of microbes in the human body. Rarely, however, sometimes deadly responses happen with consumption of Septran. These responses tackle "Stevens-Johnson-syndrome" (extreme emissions around the many parts of the body), dynamic breaking down on the external layer of the dermis, sudden and serious harm to the liver, agranulocytosis, and an absence of RBC & WBC…. Read More Read More. ...
External layer of cells that form the wall of the blastocyst. Plays an important role in embryonic nesting and later goes to form the placenta.
Single-cell RNA-Seq RNA from medial ganglionic eminence at E11.5, E13.5, E15.5 or E17.5. The ID of this project in Genentechs ExpressionPlot database is PRJ0007389 Overall design: Single-cell RNA-Seq from medial ganglionic eminence at E11.5, E13.5, E15.5 or E17.5.
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In this episode, we review the high-yield topic of Tibial Eminence Fractures from the Pediatrics section. - Send in a voice message: https://anchor.fm/orthobullets/message. ...
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Chicory has a great deal to offer, even when you use it as a natural caffeine-free coffee substitute, it retains all of its health loving properties.
موقع مکتب سماحة السيد عادل العلوي .::. المجمع الإسلامي العالمي للتبليغ و الإرشاد .::. سایت دفتر حاج سید عادل علوی .::. بنیاد اسلامی جهانی تبلیغ و ارشاد
A skewed plot set in a tight residential area in tripunithura, ernakulam and a one line expectation from the client “a spacious, well ventilated house with minimalistic unique features” has evolved into a...
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Authors of the highest eminence seem to be fully satisfied with the view that each species has been independently created. To my mind it accords better with what we know of the laws impressed on matter by the Creator, that the production and extinction of the past and present inhabitants of the world should have been due to secondary causes, like those determining the birth and death of the individual. When I view all beings not as special creations, but as the lineal descendants of some few beings which lived long before the first bed of the Silurian system was deposited, they seem to me to become ennobled. Judging from the past, we may safely infer that not one living species will transmit its unaltered likeness to a distant futurity. And of the species now living very few will transmit progeny of any kind to a far distant futurity; for the manner in which all organic beings are grouped, shows that the greater number of species of each genus, and all the species of many genera, have left no ...
BioAssay record AID 177098 submitted by ChEMBL: Duration of anti-ovulatory activity was measured at noon on proestrous and the vehicle was 50% propylene glycol /0.9 % mazola corn oil.
Catharine Cox published two studies of highly eminent creators and leaders, the first in 1926 as the second volume of Termans landmark Genetic Studies of Genius and the second in 1936 as a coauthored article. The former publication concentrated on the relation between IQ and achieved eminence, and the latter focused on early physical and mental health. Taking advantage of unpublished data from the second study, we examined, for the first time, the relationships among achieved eminence, IQ, early physical and mental health, and achievement domain. The correlation and regression analyses showed, for these 282 individuals, that eminence is a positive function of IQ and that IQ is a positive function of mental health and a negative function of physical health, implying an indirect effect of physical and mental health on eminence. Furthermore, levels of early physical and mental health vary across 10 specific domains of achievement ...
Catharine Cox published two studies of highly eminent creators and leaders, the first in 1926 as the second volume of Termans landmark Genetic Studies of Genius and the second in 1936 as a coauthored article. The former publication concentrated on the relation between IQ and achieved eminence, and the latter focused on early physical and mental health. Taking advantage of unpublished data from the second study, we examined, for the first time, the relationships among achieved eminence, IQ, early physical and mental health, and achievement domain. The correlation and regression analyses showed, for these 282 individuals, that eminence is a positive function of IQ and that IQ is a positive function of mental health and a negative function of physical health, implying an indirect effect of physical and mental health on eminence. Furthermore, levels of early physical and mental health vary across 10 specific domains of achievement ...
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Gonadotropin-releasing hormone (GnRH) neurons are the final output neurons of a hypothalamic network controlling fertility in mammals. They release GnRH from axon terminals into the portal blood circulation of the pituitary, where GnRH triggers the secretion of luteinizing and follicle stimulating hormones. GnRH neuron anatomy, morphology and physiology have been studied extensively at the levels of the cell bodies and dendrites in the basal forebrain and axons in the median eminence. However little is known about the subcellular origin of the axon and the physiological role of the dense GnRH fiber innervation of the organum vasculosum of the lamina terminalis (OVLT). Using a cell-filling approach in acute brain slices from GnRH-green fluorescent protein mice, GnRH neuron morphology was analyzed with a confocal microscope. The vast majority (83%) of GnRH neurons were found to extend long dendrites in the direction of the median eminence. When these dendrites were analyzed in a novel brain slice ...
The nature of the genetic defects which define the obese (ob) and diabetes (db) loci in mice remain unknown, but both produce similar syndromes when maintained in the same strain of mice. There is some evidence suggesting a lesion in the central nervous system (CNS) in db/db mice, while ob/ob mice appear to have a primary lesion outside the CNS. In a search for further evidence of a unique central lesion in db/db mice, we have examined neuropeptide content in selected, microdissected brain areas in both of these mutants and lean controls. In order to rule out possible interactions of the db mutation with the genetic background, diabetes mice of both C57BL/KsJ and C57BL/6J strains were studied. When concentrations of nine neuropeptide immunoreactivities were examined in up to seven microdissected areas of the brain, C57BL/6J ob/ob mice showed only one reproducible alteration, a lower content of beta-endorphin-like immunoreactivity (LI) in the preoptic area at both 3 and 6 weeks of age as
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In neuroanatomy and neuroembryology, a ganglionic eminence (GE) is a transitory brain structure that guides cell and axon migration. It is present in the embryonic and fetal stages of neural development found between the thalamus and caudate nucleus. The eminences are found in the ventral ventricular zone of the telencephalon, where they facilitate tangential cell migration during embryonic development. Tangential migration does not involve interactions with radial glial cells; instead the interneurons migrate perpendicularly through the radial glial cells to reach their final location. The characteristics and function of the cells that follow the tangential migration pathway seem to be closely related to the location and precise timing of their production. GABAergic interneurons migrate tangentially, and the GEs contribute significantly to building up the GABAergic cortical cell population. Another structure that the GEs contribute to is the basal ganglia. The GEs also guide the axons growing ...
TY - JOUR. T1 - Perfusion of the rat anterior pituitary via a cannulated portal vessel.. AU - Porter, J. C.. AU - Mical, R. S.. AU - Ondo, J. G.. AU - Kamberi, I. A.. PY - 1972. Y1 - 1972. UR - http://www.scopus.com/inward/record.url?scp=0015258166&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0015258166&partnerID=8YFLogxK. M3 - Article. C2 - 4536844. AN - SCOPUS:0015258166. VL - 158. SP - 249. EP - 269. JO - European Journal of Endocrinology. JF - European Journal of Endocrinology. SN - 0804-4643. ER - ...
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5. Involution - Additional to previous course of action a distinct involution also occurs at the blastoporal borders. This is mainly dynamic at the median dorsal lip and gradually more less as it shifts across either side until it reaches the ventral lip where it constant.Throughout this progression, cells positioned beside the superior boundaries of the blastoporal lip migrate over the lip to the interior portion of the lip. These cells are remained within the embryo along the internal edge of the blastopore. This indicates the root of archenteron is composed of involuted cells and beyond this the external layer known as the ectoderm. The base and lateral sides are enclosed mainly of endodermal cellular material, which have been established from larger yolk cells, situated in the vegetal pole of the blastula. - In the final phases of the gastrula development, the cells contributing to the floor of the archenteron, thin out significantly where they surround the blastocoel. The hemispherical ...
Rotavirus triple-layered particles. Rotavirus virions are triple-layered particles with icosahedral symmetry. The spike protein and the glycoprotein VP7 compose the external layer. Meanwhile, a unique component, VP6, is part of the middle layer. The VP2 icosahedral internal layer or virus core e ...
Its important to have a general understanding of how the skin grows and the fact that it has a normal peeling process called exfoliation in order to appreciate the science behind the non-surgical facelift. The non-surgical facelift produces an immediate improvement in the skins appearance on several levels. Plus, application of the non-surgical facelift on a regular basis actually produces a regenerating effect. It has been experimentally shown that regular removal of the external layers of stratum corneum stimulates cell proliferation in the cellular layers of the epidermis. ...