In this analysis of a large multinational cohort increasing maternal age did not appear to impact negatively on offsprings adult respiratory health. Higher maternal age at delivery was related to increasing levels of FEV1 and higher FEV1/FVC ratio in the offspring, possibly more pronounced among females. Moreover, increasing maternal age at delivery was related to decreasing risk of asthma and asthma symptoms among female offspring, while these associations were not present among male offspring. The results were robust across countries with different sociocultural characteristics, and with adjustment for a range of factors (maternal smoking, asthma and educational level; and offspring number of older siblings, single child, number of siblings, birth weight, age, BMI, daycare attendance before 5 years of age and living environment in early childhood).. The impact of maternal age on lung function is a novel finding. It is of interest that effects were observed for FEV1 and FEV1/ FVC ratio rather ...
Please cite this paper as: Aasheim V, Waldenström U, Hjelmstedt A, Rasmussen S, Pettersson H, Schytt E. Associations between advanced maternal age and psychological distress in primiparous women, from early pregnancy to 18 months postpartum. BJOG 2012;119:1108-1116.. Objective To investigate if advanced maternal age at first birth increases the risk of psychological distress during pregnancy at 17 and 30 weeks of gestation and at 6 and 18 months after birth.. Design National cohort study.. Setting Norway.. Sample A total of 19 291 nulliparous women recruited between 1999 and 2008 from hospitals and maternity units.. Methods Questionnaire data were obtained from the longitudinal Norwegian Mother and Child Cohort Study, and register data from the national Medical Birth Register. Advanced maternal age was defined as ≥32 years and a reference group of women aged 25-31 years was used for comparisons. The distribution of psychological distress from 20 to ≥40 years was investigated, and the ...
It is fairly common in our society for women to delay pregnancy, especially when compared to our parents generation. For a variety of reasons including career goals and delayed marriage, many women are waiting until their 30s to start families. Waiting may consider these moms "high-risk" by most obstetricians for being of advanced maternal age, over 35 years old. Advanced maternal age is a well known risk factor for having a child with a chromosomal abnormality, such as Downs Syndrome. However, there has been little information on maternal age in relation to congenital abnormalities, or physical defects.. According to a new study, advanced maternal age might not be as risky as some may believe. In fact, it may actually decrease the risk of congenital malformations.. "…this retrospective study used obstetric and ultrasound information collected from over 76,000 women at the time they presented for their routine second trimester ultrasound at Washington University in St. Louis (Mo.). ...
Objectives: To evaluate the associations between maternal age and obstetric and neonatal outcomes in primiparous women with emphasis on teenagers and older women. Design: A population-based cohort study. Setting: The Swedish Medical Birth Register. Participants: Primiparous women with singleton births from 1992 through 2010 (N=798 674) were divided into seven age groups: less than17 years, 17-19 years and an additional five 5-year classes. The reference group consisted of the women aged 25-29 years. Primary outcome: Obstetric and neonatal outcome. Results: The teenager groups had significantly more vaginal births (adjusted OR (aOR) 2.04 (1.79 to 2.32) and 1.95 (1.88 to 2.02) for age less than17 years and 1719 years, respectively); fewer caesarean sections (aOR 0.57 (0.48 to 0.67) and 0.55 (0.53 to 0.58)), and instrumental vaginal births (aOR 0.43 (0.36 to 0.52) and 0.50 (0.48 to 0.53)) compared with the reference group. The opposite was found among older women reaching a fourfold increased OR ...
Advanced Maternal Age AMA Definition - Advanced maternal age (AMA) refers to a pregnancy in which the mother is over the age of 35. The age of the mother....
Traditionally, women aged 35 and over who become pregnant are referred to as AMA, or advanced maternal age. But is this a thing of the past?
We extracted from the hospital episode statistics database records of women who delivered in English NHS acute trusts between 1 January and 31 December 2008. We restricted the sample to women aged between 15 and 44 years who had a singleton birth, and to NHS trusts whose obstetric units had more than 1000 deliveries in the 12 month period. Deliveries were included if the record contained information about mode of delivery in either the maternity tail or the procedure fields (OPCS codes: R17 to R25). The method of delivery was obtained primarily from the procedure fields. Where data had not been entered to these fields (0.6% of women), information was taken from the maternity tail. An elective caesarean section was defined by OPCS code R17, or by "mode of delivery" code 7 when data were obtained from the maternity tail. An emergency delivery was defined by codes R18 or 8, respectively.. Data on maternal age at delivery, ethnicity, and the NHS trust and region of treatment were obtained from the ...
I had a baby at age 27, which is above the mean age for a first baby in this country (25, I think), but well below the mean age for a first baby amongst my colleagues. Of the fifty or so women I went to med school with, I know of only FIVE who have had kids, even though the very youngest of us are almost thirty. I remember on my Labor and Delivery rotation in med school, all the girls in my class used to joke about how when they were up on the L&D board someday, thered by an "AMA" note by their name. (AMA = Advanced Maternal Age ...
0018 Background. Blood pressure (bp) level after birth may reflect the fetal cardiovascular environment, but few data exist on newborn bp. Methods. We report findings from a new cohort of pregnant women and their offspring, Project Viva. Enrollment as of September, 2000, is 1338 pregnant women (of a target 6000), and 581 have delivered. Data collected include maternal dietary, sociodemographic, economic, psychological, lifestyle, and clinical variables; and infant bp, pulse rate, length, weight, and circumferences measured during the first 2 days of life. We averaged 5 systolic bp readings taken with a Dinamap automated bp recorder. This abstract is limited to the first 260 measured newborns (131 girls and 129 boys) and partial maternal data. Results. The highest newborn systolic bp was in children of the oldest mothers, and the lowest in the maternal age group 20-24 years (⇓Table). Multivariate adjustment for infant birth weight and sex and for maternal body mass index, pregnancy weight gain, ...
Babymed.com articles & information about Advanced maternal age for mothers, expecting mothers, and soon to be expecting mothers.
At present there are three probable genetic mechanisms for the inheritance of AIS autosomal dominance (this produces a high proportion of affected members in a family), X linked transmission (X is the female sex chromosome) and what is called multifactorial. The last of these is particularly important and multiple genes (a gene is an active or functional segment of DNA which makes up a chromosome) are implicated. It is now known that environmental factors, using this term in a broad but
I am currently in my second IVF cycle. I transferred 3 embryos. All were at the 8 cell stage and all have a perfect rating of 1. I was a bit leary about doing this, but due to my age, (Im 39, going on 40 in Sept) I decided to go ahead and take the chance. Advanced maternal age plays a role in pregnancy success. I just had my first U/S and they found 2 sacs and we were able to see both fetal hearbeats. Im a bit guarded because I know that there is a thing called Vanishing Twin. There is a chance (about 40%) that I can lose one. Im delighted that this worked, but at the same time, at 6 weeks, its still a bit early for us to celebrate. After 12 weeks (first trimester) maybe ill be able to breathe, but until then, Im being cautious. What is your status with IVF? Is this your first time? Age ...
So today were going to talk about age now and when you get into the late 30s even over 35, they start to call you advanced maternal age.
Werlins research answers questions the causes of IVF failure in women of advanced maternal age. PGD research gives insights to increase fertility success.
46, married, female, built a family the "new-fashioned" way. Azoosperma was a hurdle, and I was also "of advanced maternal age." Were now raising two beautiful daughters and our family is complete (and insurance wouldnt cover another fresh cycle at my "advanced" age anyhow ...
46, married, female, built a family the "new-fashioned" way. Azoosperma was a hurdle, and I was also "of advanced maternal age." Were now raising two beautiful daughters and our family is complete (and insurance wouldnt cover another fresh cycle at my "advanced" age anyhow ...
Premature and congenitally ill babies are born as a consequence of late maternal age, induced fertility, labour treatments, deprived prenatal care and modification in lifestyle predilections.
In 2008, 41% of all births in the United States occurred outside of marriage. Children born to unmarried mothers are often disadvantaged in young adulthood, including being less likely to graduate high school. In recent years, the age composition of mothers has changed; teen births declined substantially, and non-marital births are now most heavily concentrated among women in their twenties. This paper examines whether maternal age at birth differentiates the educational outcomes of children, and if this varies by maternal marital status. Data are from the linked Children and Young Adult sample of the 1979 National Longitudinal Survey of Youth (NLSY79). We find significant differences in the likelihood of high school graduation among youth born to a never-married versus a married mother. These disparities remain even after including controls for maternal age at birth, as well as social and economic characteristics of mothers prior to the birth. The marital status gap in the likelihood of ...
Even before full implementation of the policy for combined risk assessment during the first trimester in Denmark, the number of infants born with Downs syndrome decreased by about 50% and the number of cases diagnosed prenatally increased by around 30%. The number of fetuses and newborn infants with Downs syndrome diagnosed prenatally or postnatally increased in the period 2000-5, with a slight decline in 2006 (fig 2). This was partly due to increasing maternal age, but was as expected because more fetuses with Downs syndrome are lost spontaneously than those that are chromosally normal. This increased rate has been estimated at around 25% from week 14 to term.[4] Based on the known distribution of maternal age at delivery in 2005 and 2006, 132 and 135 infants with Downs syndrome would have been expected in our population of 65 000 liveborn infants if the mothers had no prenatal intervention. Downs syndrome was diagnosed in 31 infants postnatally and 130 prenatally in 2005 and in 32 infants ...
Even before full implementation of the policy for combined risk assessment during the first trimester in Denmark, the number of infants born with Downs syndrome decreased by about 50% and the number of cases diagnosed prenatally increased by around 30%. The number of fetuses and newborn infants with Downs syndrome diagnosed prenatally or postnatally increased in the period 2000-5, with a slight decline in 2006 (fig 2). This was partly due to increasing maternal age, but was as expected because more fetuses with Downs syndrome are lost spontaneously than those that are chromosally normal. This increased rate has been estimated at around 25% from week 14 to term.[4] Based on the known distribution of maternal age at delivery in 2005 and 2006, 132 and 135 infants with Downs syndrome would have been expected in our population of 65 000 liveborn infants if the mothers had no prenatal intervention. Downs syndrome was diagnosed in 31 infants postnatally and 130 prenatally in 2005 and in 32 infants ...
A mothers age at menopause may predict her daughters fertility in terms of the numbers of eggs remaining in her ovaries, according to the new research published online in Europes leading reproductive medicine journal Human ...
There is no definite way to avoid having a baby with Downs syndrome. There will always be probabilities, sometimes greater than others. A big factor is the age at which amother conceives. At age 25, probabilities are 1 in 1,250; at age 40 probabilities increase to 1 in 100 (Shriver 2007). Parents with Down syndrome, or with an abnormal 21 chromosome are also at higher risk of conceiving a child with the condition. Many tests can be done before the child is born so that the parents may prepare for the childs special needs (Shriver 2007).. A series of two surveys on exposure to contraceptive pills prove that there may be an impact at or around the time of pregnancy on Down syndrome probabilities. A study done by Martinez-Frias and Read infer that that there will be a slight increased rate of Down Syndrome for maternal age group 20-29, a decreased rate for maternal age group 30-39 (Read). ...
It has been known for more than half a century that the risk of conceiving a child with trisomy increases with advanced maternal age However the origin of the high susceptibility to nondisjunction of whole chromosomes and precocious separation of sister chromatids leading to aneuploidy in aged oocytes and embryos derived from them cannot be traced back to a single disturbance and mechanism Instead analysis of recombination patterns of meiotic chromosomes of spread oocytes from embryonal ovary and of origins and exchange patterns of extra chromosomes in trisomies as well as morphological and molecular studies of oocytes and somatic cells from young and aged females show chromosome specific risk patterns and cellular aberrations related to the chronological age of the female In addition analysis of the function of meiotic and cell cycle regulating genes in oogenesis and the study of the spindle and chromosomal status of maturing oocytes suggest that several events contribute synergistically to ...
The study by Nybo Andersen and colleagues is undoubtedly generalizable. Because of its population-based design, it provides the best estimates to date of the incidence of pregnancy loss and its association with maternal age and previous reproductive history. The authors do not attempt to explain their findings. The cause of miscarriages in older women now seems to be well understood: Chromosomal deletions and fatal trisomies resulting from nondisjunction during meiosis are probably the underlying biological mechanisms (1). Whether these mechanisms also explain the increased likelihood of ectopic pregnancy in older women remains to be seen. The study by Nybo Andersen and colleagues favors the hypothetical role of the fertilized egg itself in the pathogenesis of ectopic nidation. Accumulation of other risk factors with increasing age (i.e., those impairing tubal function) might also explain the association (2). The relation between stillbirth and maternal age, straightforward as it may seem, is ...
A group of patients (150) suffering from keratoconus were asked their mothers age at their birth. A statistically significant excess of older mothers as compared with the general population was found. The social class of the patients was found to have a distribution different from the general population, and it is suggested that this is related to the patients maternal age. ...
The association of maternal age with infant mortality, child anthropometric failure, diarrhoea and anaemia for first births: evidence from 55 low- and middle-income countries ...
A pregnancy over 35 is considered a geriatric pregnancy. In recent years, geriatric pregnancy has come to be known as the pregnancy of advanced maternal age.
Dont get me wrong, I appreciate the red carpet treatment. I love knowing that my odds of having a Down Syndrome or Trisomy 18 baby are LOW LOW LOW after the testing was done, we have none of the genetic markers. Next well do neural tube defect testing so you know - MORE PICTURES! Plus I get to see the sex by then so thatll be fun ...
Dont get me wrong, I appreciate the red carpet treatment. I love knowing that my odds of having a Down Syndrome or Trisomy 18 baby are LOW LOW LOW after the testing was done, we have none of the genetic markers. Next well do neural tube defect testing so you know - MORE PICTURES! Plus I get to see the sex by then so thatll be fun ...
Q: Ive always had a pretty healthy diet but now that I am pregnant, what vitamins, minerals and other nutrients are critical to include for optimal health for me and my baby?. Response from Margaret Connor, MPH, CHC, The Wellness Pantry. A: It sounds like you have already helped yourself and your baby by eating healthy before your pregnancy began, which is terrific. Now lets examine how our metabolic needs do increase during pregnancy. The following vitamins and minerals play a special role in your health and that of your childs during pregnancy (and often postpartum as well). One exciting detail to consider is that the absorption of nutrients across our intestinal barrier typically increases during pregnancy, so eating good sources of these vitamins and minerals will go a long way towards keeping you equipped with the necessary nutrients.. FOLATE - Youve probably heard your OB mention this as a valuable supplement that you might have been taking even before you became pregnant. The evidence ...
Advanced Paternal Age APA Definition - Advanced paternal age (APA) most commonly refers to a man who is 40 years or older at the time of conception. As a....
BabyAfter40.com: Women who conceive and deliver after the age of 50 years, following egg donation, do not have a reduced parenting capacity compared with younger women, according to new study findings.
I did discuss a little bit of a plan with my doctor. She didnt want to make any decisions until we get there, and I think that is the right thing to do in my case. I am on the edge of "advanced maternal age". I cant decide if I should just wait the extra month and be automatically high risk or leave that designation up to chance. It would eliminate some arguments with my insurance company. My doctor didnt really think losing weight would help me much, but she agreed that "getting in fighting shape" couldnt hurt. I believe that my pregnancy was a failed "stress-test" and a wake-up call to start taking care of myself and get healthy. My BP is still higher than it was pre-pregnancy, so I wouldnt be surprised if I end up having to deal with that at some point. I didnt discuss it with her at my previous appointments because I thought it would go down if I got the weight off. We will end up talking about it at my first appointment or next checkup ...
I did discuss a little bit of a plan with my doctor. She didnt want to make any decisions until we get there, and I think that is the right thing to do in my case. I am on the edge of "advanced maternal age". I cant decide if I should just wait the extra month and be automatically high risk or leave that designation up to chance. It would eliminate some arguments with my insurance company. My doctor didnt really think losing weight would help me much, but she agreed that "getting in fighting shape" couldnt hurt. I believe that my pregnancy was a failed "stress-test" and a wake-up call to start taking care of myself and get healthy. My BP is still higher than it was pre-pregnancy, so I wouldnt be surprised if I end up having to deal with that at some point. I didnt discuss it with her at my previous appointments because I thought it would go down if I got the weight off. We will end up talking about it at my first appointment or next checkup ...
A new study reveals that maternal demographic factors such as social status, ethnicity and maternal age can predict the likelihood of operative births in the UK.
Two studies of its abundance in Palau were conducted using point counts from April to May 1991 (Wiles et al. 1997) and from April to May 2005 (G. Wiles, unpublished data). Both studies were inconclusive about total numbers, but provided baseline encounter rates that could, and should, be repeated in the future to determine population trends. Data from 2005 have not yet been analyzed, but bats were common in many locations. Numbers appeared to have increased since 1991. Prior to the early 1990s the species had gone through a large decline due to commercial exploitation with thousands of bats being exported annually to markets in Guam and the Northern Marianas. In the 1940s the species was considered abundant (Marshall 1945, as reported in Wiles et al. 1997), but by the 1970s numbers were starting to decline (Owen 1977), and at some point in the 1980s this trend reversed itself with less bats being exported (Wiles et al. 1997 ...
Advanced maternal age has been shown to influence follicular and luteal dynamics in bovine ovary resulting in reduced fertility. The overall objective of the four studies presented in this thesis is to identify the maternal age-associated transcriptional changes in granulosa cells of the dominant follicles during follicle development. In the first study, mRNA expression levels of housekeeping genes were measured by real-time quantitative PCR (RT-qPCR) in granulosa cells of dominant follicles and FSH-stimulated follicles to select and validate suitable reference genes for relative gene expression analyses during maternal and follicular aging. Stability of six reference genes (GAPDH, ACTB, EIF2B2, UBE2D2, SF3A1 and RNF20) was analyzed using GeNorm, DeltaCT and NormFinder programs and comprehensive ranking order was determined based on these programs. Geometric mean of multiple genes (UBE2D2, EIF2B2, GAPDH and SF3A1) was more appropriate reference control than individual genes for the comparison of ...
A study in the city of Sakarya in Turkey determines that postnatal infant death rate is 2.5% in adolescent pregnancies and 0.1% adult pregnancies [26]. Malabarey, et al. [7] in their studies in the USA evaluate the effect of young maternal age on adverse obstetrical and neonatal outcomes. They stated that the rate of infant deaths in pregnant adolescents below 15 is 0.86%, and it is 0.41% in pregnant adolescents over 15. In another study conducted in the USA, the rate of neonatal mortality is reported as 7.3% between the ages of 10-15, 4.9% between the ages of 16-17 and 4.1% between the ages of 18-19, so, the younger the mothers are, the higher the rate of deaths is [27]. In a study conducted in India, it is stated that the rate of infant deaths earlier than 48 hours is 5.1% in adolescents and it is 1.7% in adults, which is significantly a high rate [15]. The increased neonatal mortality in infants born to teenage mothers might be mediated by low weight gain during pregnancy, preterm birth, ...
Mitochondria are the most abundant organelles within the oocyte and are fundamental for energy metabolism, spindle formation and chromosome segregation. Therefore it is likely that a reduction in mitochondria number or function may explain the decreased quality, developmental potential and increased frequency of chromosomal non-disjunction in oocytes from older women, especially when coupled with IVF stimulation regimens. The aim of this study was to delineate, using a novel bovine model of human IVF stimulation, the effects of ovarian stimulation regimens and maternal age on mitochondrial DNA copy number and function of the cumulus-oocyte-complex. Seven young (4 years old) and five old (11 years old) cloned cows with an identical genetic background, and managed as one herd, were subjected to repeated rounds of ovarian stimulation; four natural (hCG), three mild (FSH and hCG) and two heavy stimulated (GnRH agonist, FSH and hCG) cycles. Individual cumulus-oocyte-complexes were collected. The ...
Egg infertility is a predisposition to miscarriages, infertility, and trisomic pregnancies caused by increased frequency of chromosome segregation errors in the eggs of women of advanced maternal age (AMA). Egg infertility is now a significant public health issue, with 1 in 5 US women now attempting her first pregnancy after age 35. Increased rates of egg infertility temporally coincide with rising levels of FSH that occur with age. By age 42, up to 87% of embryos are aneuploid, and 40-50% of women experience egg infertility. An Introductory Editorial will present an overview of causative factors and potential therapeutic strategies to prevent egg aneuploidy and infertility. Papers in series will be comprised of data drawn from studies performed both in animals and in humans. Part I will discuss endocrine and other molecular changes implicated in the pathogenesis of AMA oocyte aneuploidy and infertility. Section 1 will discuss defects that emerge with age in controlling the fidelity of meiotic oocyte
BACKGROUND Women in high resource nations are increasingly delaying childbearing until their thirties. Delayed childbearing poses challenges for the spacing of a womans pregnancies. Inter-pregnancy intervals |12 months are associated with risk for adverse pregnancy outcome, yet increased maternal age at delivery is linked with increased risk. The optimal inter-pregnancy interval for older mothers is uncertain. This systematic review will aim to assess the relation between inter-pregnancy interval and perinatal and maternal health outcomes in women who delay childbearing to age 30 and older. METHODS We will search MEDLINE, CINAHL, and EMBASE databases for peer-reviewed articles on the effects of inter-pregnancy interval on perinatal and maternal health outcomes among women over 29 years at the time of first birth, in high-income countries. To assess the quality of studies, the Cochranes Collaboration tool for assessing risk of bias will be used for randomized controlled trials, and the Newcastle
Earlier age of menarche has been associated with an increased risk of chronic diseases during adulthood, but whether early menarche has intergenerational effect is not clear. In this population-based cross-sectional study, we recruited children from 26 primary schools using cluster random probability sampling in Shanghai, China, in 2014. We used multiple linear regression models to estimate the adjusted associations of maternal age of menarche (MAM) with offspring body mass index (BMI). We also used the mediation analysis to examine the contribution of maternal BMI and gestational diabetes to offspring BMI. A total of 17,571 children aged 6-13 years were enrolled, of whom 16,373 had their weight and height measured. Earlier MAM was associated with higher child BMI in boys (− 0.05 z-score per year older MAM, 95% CI − 0.08 to − 0.02) and in girls (− 0.05 z-score per year older MAM, 95% CI − 0.07 to − 0.02). Maternal BMI positively mediated the association of MAM with offspring BMI in both
Background The incidence rates of childhood onset type 1 diabetes are almost universally increasing across the globe but the aetiology of the disease remains largely unknown. We investigated whether birth order is associated with the risk of childhood diabetes by performing a pooled analysis of previous studies. Methods Relevant studies published before January 2010 were identified from MEDLINE, Web of Science and EMBASE. Authors of studies provided individual patient data or conducted pre-specified analyses. Meta-analysis techniques were used to derive combined odds ratios (ORs), before and after adjustment for confounders, and investigate heterogeneity. Results Data were available for 6 cohort and 25 case-control studies, including 11 955 cases of type 1 diabetes. Overall, there was no evidence of an association prior to adjustment for confounders. After adjustment for maternal age at birth and other confounders, a reduction in the risk of diabetes in second- or later born children became ...
Women having both first trimester nuchal translucency and second trimester serum screening tests are likely to receive two different Down s syndrome risks. Neither will be correct, and we describe how to calculate a valid combined risk. This uses the reported serum-based risk and a likelihood ratio derived from the nuchal translucency report....
Downloadable (with restrictions)! We examine birth order effects on academic achievement for ten-year-old students using data for the entire population of fifth graders in Norway 2007/2008. The analysis thus adds to a thin empirical literature focusing on birth order effects among young children. We find that being firstborn confers a significant advantage in families with two, three and four children. The analysis makes two other contributions. First, we provide evidence that unless mothers age at childbirth is included among the control variables, only small and imprecise birth order effects are revealed in families with low socioeconomic status. Second, we provide some evidence that the birth order effects differ across families with highly educated and less educated mothers, which lend support to the resource dilution model over the confluence model.
Older paternal and maternal age is associated with having a child with autism, according to a study from the University of Texas Health Science Center in
To describe the obstetric outcome in women at ages >= 45. A retrospective cohort study on a large existing database covering all deliveries in the Flanders region, Belgium, was performed, comparing obstetric outcomes at age 25, 35, 40 and 45 or older, for the period 2005-2010. In the period studied, 421 women gave birth at maternal age >= 45 vs 3,405, 15,206, 22,586 at ages 40, 35 and 25, respectively. With advancing maternal age, a significant linear increase for low birth weight (< 2,500 g) and preterm delivery (< 37, < 35 weeks and < 29 weeks), maternal hypertension and diabetes, both primary and secondary caesarean section, was noted. Between ages 40 and >= 45, both fetal and early neonatal death demonstrated a significant rise from 4.9/1,000 and 1.8/1,000 to 26/1,000 and 9.5/1,000, respectively. With advancing maternal age, a gradual but not statistically significant decline in the proportion of male fetuses was noted, from 51.6% at 25, to 47.2% in the oldest group. Multivariate analysis ...
The primary aim of this study was to determine the predictive value of prenatal ultrasound and echocardiography for prognosis in congenital heart disease (CHD) with coexisting diaphragmatic hernia (DH) in a tertiary care center. Eleven records from the database of the Department for Diagnoses and Prevention of Congenital Malformations, Polish Mothers Memorial Hospital Research Institute, were reviewed. The mean maternal age was 29,2 ± 5,1 years, and the mean gestational age at the time of diagnosis was 28,4 ± 6,7 weeks. No information was available for children discharged from hospital. Data of eight cases of prenatal DH and complex heart disease from the literature were also analyzed. Three fetuses survived the neonatal period. In each of these, CHD was other than the urgent or critical type, defined as not requiring cardiac surgical intervention in the first day or month of life. Both sets of data collected from our center and the published literature confirmed the unfavorable prognosis for ...
Teenage pregnancy and childbearing have become pressing social concerns in the United States, where approximately one million teenagers become pregnant each year, and half that number give birth.1 An enormous quantity of research has shown that teenage childbearing is linked to a host of negative social, economic and medical consequences for both mother and child.
I am on my knees, my face in the seat of a rocking recliner. The clock passes midnight and its just the four of us-me, my husband, our baby and a nurse-inside an abortion clinic 90 miles from our home and friends. There is no bed or doctor to ease my way toward delivery of my son, whose life I am ending as my first true act of motherhood.. The nightmare began unfolding for my husband, David, and me on Halloween 2006, the day I answered a call at the office from my doctor informing me of the far-from-optimal results of my prenatal Quad screening, a series of tests Id agreed to due to my "advanced maternal age" of 35. We were a solid, mature couple reveling in the joy of my growing belly and the limitless possibilities of this much-wanted first pregnancy. A negative outcome was something wed never considered, nor been prepared for by my doctor.. My OBs office sprang into action, securing me a same-day appointment with a high-risk doc who would provide a level II ultrasound and an ...