Expression of MAP2K6 (MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3) in ovary tissue. Antibody staining with HPA031134 and CAB007744 in immunohistochemistry.
A Pasadena man will spend the next few weekends in jail as he serves a six-day intermittent sentence. Terrence Carter, 62, was sentenced in provincial court in Corner Brook on Tuesday for possession of a controlled drug or substance, namely
Oscar Juicers The Oscar juicer is an International Award winning 3 stage single auger stonemill-type juicer designed to extract the liquid contents and some
The Arabidopsis thaliana genome contains genes encoding 10 MAP kinase kinase (MKK) and 20 Map kinase (MAPK) proteins, however the exact relationship between upstream MKK activators and downstream MAPK protein partners has not fully elucidated. In this study, the yeast two -hybrid system was used to identify protein-protein interactions between all Arabidopsis MAPKs and MKKs. In the yeast two- hybrid assay, the result from the qualitative β-galactosidase filter assay showed that 6 MAPK proteins interacted with 6 MKK proteins. Quantitative β-galactosidase liquid assay was used to confirm the interactions between MAPK and MKK in yeast. The BiFC approach was used to test whether MKK1, MKK2 and MKK6 associated with MPK4 and MPK11 in vivo in Arabidopsis. In these assays, GFP fluorescence was observed in the protoplasts suggesting that MKK1, MKK2 and MKK6 interact with MPK4 and MPK11, respectively. However, evidence of reciprocal interaction was only seen with the combination of MKK1 and MPK11, and ...
MAPK is involved in the action of most nonnuclear oncogenes. It is responsible for cell response to growth factors such as BDNF or nerve growth factor. Extracellular stimuli lead to activation of a MAP kinase via a signaling cascade ("MAPK cascade") composed of MAP kinase, MAP kinase kinase (MKK or MAP2K), and MAP kinase kinase kinase (MKKK or MAP3K, EC 2.7.11.25). A MAP3K that is activated by extracellular stimuli phosphorylates a MAP2K on its serine and threonine residues, and then this MAP2K activates a MAP kinase through phosphorylation on its serine and tyrosine residues. This MAP kinase signaling cascade has been evolutionarily well-conserved from yeast to mammals. ...