TY - JOUR. T1 - Modulation of pituitary luteinizing hormone releasing hormone receptors by sex steroids and luteinizing hormone releasing hormone in the rat. AU - Marchetti, B.. AU - Reeves, J. J.. AU - Pelletier, G.. AU - Labrie, F.. PY - 1982. Y1 - 1982. N2 - The effect of sex steroids on pituitary luteinizing hormone releasing hormone (LHRH) receptor number and affinity was studied in adult castrated male and female rats treated for 2 weeks with 17β-estradiol (E2), testosterone (T), 5α-dihydrotestosterone (DHT) or progesterone (P) alone or in combination. The effect of chronic treatment with the potent LHRH agonist [D-Ser(TBU)6, des-Gly-NH210] LHRH ethylamide, Buserelin, was studied in intact and castrated animals. [125I]-Buserelin was used as tracer to measure LHRH receptors in individual pituitaries. Daily treatment of intact male rats for 2 weeks with Buserelin (200 ng) increased pituitary LHRH receptor concentration while the same treatment in castrated animals reversed by 60% the ...
Patterns of pulsatile luteinizing hormone secretion before and during the onset of puberty in boys: a study using an immunoradiometric assay.: To study spontane
TY - JOUR. T1 - Changing dose of progesterone results in sudden changes in frequency of luteinizing hormone pulses and secretion of 17β-estradiol in bovine females. AU - Bergfeld, E. G.M.. AU - Kojima, F. N.. AU - Cupp, A. S.. AU - Wehrman, M. E.. AU - Peters, K. E.. AU - Mariscal, V.. AU - Sanchez, T.. AU - Kinder, J. E.. PY - 1996/3/1. Y1 - 1996/3/1. N2 - The aim of the present study was to elucidate the time course according to which changes in circulating concentrations of progesterone influence pulsatile secretion of LH and secretion of 17β-estradiol. Our working hypothesis was that changing the dose of progesterone would result in changes in frequency of LH pulses and secretion of 17β-estradiol within 72 h. Five days after behavioral estrus, thirty-three cows were randomly assigned to one of five groups: 1) control, no treatment (CONT, n = 5); 2) treatment with two progesterone-releasing intravaginal devices (PRIDs) for 11 days (2PRID, 5-6 ng/ml plasma progesterone, n = 7); 3) treatment ...
Recent studies have shown that LH secretion is pulsatile and that LH pulse characteristics are affected by the prevailing steroid environment in both male and female rats. In the present study, a cell perifusion system was used to examine the effects of testosterone (T) and 17 beta-estradiol (E) on LHRH-stimulated pulsatile LH secretion. T inhibited LH secretion, increasing the EC50 for LHRH, while E stimulated secretion, lowering the EC50. Steroid effects were independent of both LHRH pulse amplitude and frequency. E also affected the pattern of LH secretion by facilitating both LHRH self-priming and desensitization to LHRH. These results show that steroids can affect pulsatile LH secretion by actions exerted at the pituitary level and that steroids can induce both quantitative and qualitative changes in LH secretion in the presence of an invariant LHRH stimulus. These results help to elucidate the mechanisms underlying steroid feedback in vivo, since reduction in pituitary responsiveness to LHRH may
Concentrations of bioavailable testosterone decline by 1.0-1.5% annually as men age. Reduced systemic testosterone availability is associated with decreased muscle mass, strength and aerobic capacity, decreased bone-mineral density and increased risk of hip fracture, waning sexual interest, inpaired spatial cognition and increased risk of visceral obesity, impaired glucose tolerance and coronary artery disease. Luteinizing hormone (LH) secretion often fails in healthy older individuals. In addition, aging is marked by an acceleration of LH pulse frequency, loss of high-amplitude LH pulses and disorderly release of LH and testosterone, as measured by the approximate entropy statistic. The mechanisms that underlie such complex adaptations are not known, but appear to involve multiple loci of regulatory failure ...
TY - JOUR. T1 - Exposure to alcohol in utero alters the adult patterns of luteinizing hormone secretion in male and female rats. AU - Handa, Robert J.. AU - McGivern, Robert F.. AU - Noble, Ernest SP. AU - Gorski, Roger A.. PY - 1985/11/4. Y1 - 1985/11/4. N2 - Luteinizing hormone (LH) secretory patterns were characterized in adult male and female rats exposed to ethanol during the last week of fetal life. Gonadectomized fetal alcohol exposed (FAE) males and females had significantly reduced plasma LH titers as compared to those of pair-fed (PF) controls. The phasic afternoon LH secretory response to estrogen and progesterone priming was also significantly reduced in FAE females. These differences do not appear to be a result of altered pituitary sensitivity to luteinizing hormone releasing hormone (LHRH), since the infusion of LHRH resulted in an equal response in PF and FAE females. Subsequent characterization of the episodic pattern of LH secretion in FAe males revealed significantly reduced ...
Mechanisms regulating gonadotropin surges and gonadotropin requirements for follicle emergence and selection were studied in heifers. Experiment 1 evaluated whether follicular inhibins regulate the preovulatory luteinizing hormone (LH)/follicle-stimulating hormone (FSH) surges elicited by gonadotropin-releasing hormone (GnRH) injection (Hour = 0) and the subsequent periovulatory FSH surge. Treatments included control (n = 6), steroid-depleted bovine follicular fluid (bFF) at Hour -4 (n = 6), and bFF at Hour 6 (n = 6). Gonadotropins in blood were assessed hourly from Hours -6 to 36, and follicle growth tracked by ultrasound. Consistent with inhibin independence, bFF at Hour -4 did not impact the GnRH-induced preovulatory FSH surge, whereas treatment at Hour 6 delayed onset of the periovulatory FSH surge and impeded growth of a new follicular wave. Experiment 2 examined GnRH and estradiol (E2) regulation of the periovulatory FSH surge. Treatment groups were control (n = 8), GnRH-receptor ...
REVERSAL type experiment was con- ducted in which measurements were made of plasma levels of luteinizing hormone (LH) and progesterone in six Holstein heifers dur- ing three estrous cycles when they were main- tained on either 100% or 62% of Morrisons TDN allowances. A progressive increase in plasma LH was noted from the first to third estrous cycle in heifers on the low energy in- take. This increase was first seen in the estrous peaks, but by the third cycle the basal mean for the low TDN group (2.7 ng/ml) was also significantly higher than that of the control heifers (1.9 ng/ml, P(0.005). During the first cycle, plasma progesterone was slightly higher in the low calorie group, but became progressively lower in the subsequent cycles (P,0.05 and P~0.01). Both total progester- one and progesterone concentration in corpora lutea taken on the 10th day of the third cycle were lower in the low-TDN heifers than in their normal counterparts, P,0.01 and ,0.05, respectivley. The results show that ...
The reaction of iodoacetic acid with bovine lutropin (luteinizing hormone) at pH 3.0 was specific for methionine residues; it was slow and reached its equilibrium after 12 h at 37 degrees C. The number of modified methionine residues increased proportionately with the amount of the alkylating reagent in the reaction mixture. In the presence of a 20-fold molar excess of iodoacetic acid with respect to methionine, essentially all methionine residues in both subunits of bovine lutropin were carboxymethylated. Studies of various recombinations of modified and native alpha and beta subunits showed that methionine residues in bovine lutropin were not essential for interactions between subunits. Various recombinants were characterized by polyacrylamide-gel electrophoresis and gel filtration of Sephadex G-100. Immunological cross-reactivity by radioimmunoassay of the recombinants of modified alpha and beta subunits was relatively similar to that of the native subunits. However, the biological activity ...
The possible differential regulation of pulsatile follicle stimulating hormone (FSH) and luteinizing hormone (LH) secretion in pre-pubertal children and in post-menopausal women was investigated. Children were studied for 4 h and post-menopausal women for 6 h; blood samples were taken every 10 min. Post-menopausal women were studied before and 21 days after administration of a single i.m. dose of gonadotrophin-releasing hormone (GnRH) analogue. Eight post-menopausal women and 18 children (nine boys and nine girls) were enrolled. The children were divided into two groups: A, at Tanner stages 0-1 (four boys and three girls); B, at Tanner stage 2-3 (five boys and six girls). Plasma LH and FSH concentrations were determined using an immunofluorimetric assay. Time series were analysed and the specific concordance (SC) index was computed to determine the degree of concordance between episodes of LH and FSH secretion. While children of group A had LH concentrations below the minimal detectable dose of ...
Bartke, A, "Effects of prolactin and luteinizing hormone on the cholesterol stores in the mouse testis." (1971). Subject Strain Bibliography 1971. 2423 ...
An investigation of the effects of an acute 180 degree reversal of the sleep/wake cycle on luteinizing hormone (LH) secretion was studied in three pubertal boys and the data collected was combined with that from the study of a fourth boy. Two 24 hour periods of blood sampling every 20 minutes were carried out in each of the boys, aged 14 to 15 years. The first study was conducted during a normal s
Flurkey, K; Gee, D M.; Sinha, Y N.; Wisner, J R.; J; and Finch, C E., "Age effects on luteinizing hormone, progesterone and prolactin in proestrous and cyclic c57bl/6j mice." (1982). Subject Strain Bibliography 1982. 3618 ...
Hormonal diseases If luteinizing hormone increased, it can be a symptom of diseases such as endometriosis, polycystic ovaries or exhaustion.All these ailments have additional features, chief of which is infertility.. Treatment should be adjusted individually and only after additional research.. benign or malignant tumors High levels of LH may indicate that a woman has health problems that are not related to the production of hormones.So, it could be a tumor of the adrenal or pituitary disease.The nature of the tumors may be different.. External factors that influence the amount of LH If too high luteinizing hormone (normal) women on day 4 of the cycle later, it may indicate that the fairer sex is not quite the right way of life.Often, these indicators are at the exhausting long workouts, malnutrition, starvation and stress.. ...
File scanned at 300 ppi (Monochrome) using Capture Perfect 3.0.82 on a Canon DR-9080C in PDF format. CVista PdfCompressor 4.0 was used for pdf compression and textual OCR ...
Luteinizing hormone releasing hormone - What does luteinizing hormone LH mean? Turns yellow. Luteining hormone is a peptide (not a steroid) hormone in the pituitary gland of both females and males. Its name (lh) comes from one of its actions in females, which is luteinization of ovarian granulosa cells. Luteinization means literally to turn yellow. luteinization is a necessary change in the ovary so that it can produce Progesterone after ovulation.
To investigate whether endogenous GABA participates in the control of gonadotropin secretion during the menstrual cycle, placebo or sodium valproate (DPA), an anticonvulsant drug which enhances endogenous GABA content by blocking GABA degradation, were administered to regularly cycling women both during early follicular and midluteal phase. In a first set of experiments, the effect of DPA administration (400 mg, orally) on basal gonadotropin secretion was evaluated in 13 subjects. During early follicular phase (n = 6), no significant changes in plasma gonadotropin levels were observed after DPA or placebo administration. Conversely, during midluteal phase (n = 7), DPA administration resulted in a significant fall (p less than 0.01) in plasma LH concentrations, with a maximal percent decrease of 41.8 +/- 6.7% after 120 min. No changes in plasma FSH levels were observed. In a second set of experiments, the effect of DPA pretreatment (400 mg, orally) on gonadotropin release stimulated by a pulse of ...
TY - JOUR. T1 - LH and FSH subunit mRNA concentrations during the progesterone-induced gonadotropin surge in ovariectomized estrogen-primed immature rats. AU - Brann, Darrell. AU - OConner, James. AU - Wade, Marlene. AU - Mahesh, Virendra. PY - 1992/4. Y1 - 1992/4. N2 - Progesterone is able to bring about an LH and FSH surge in the estrogen-primed ovariectomized rat while dexamethasone brings about selective FSH release. The purpose of this study was to determine if progesterone and desamethasone-induced gonadotropin secretion is accompanied by changes in LHβ and FSHβ mRNA levels. Gonadotropin α-subunit, LHβ-subunit, and FSHβ-subunit mRNA levels in the pituitary of ovariectomized rats were suppressed by estrogen treatment and dexamethasone brought about a significant increase in FSHβ mRNA within 1 h. Progesterone treatment (0900 h) led to a surge in serum LH levels, with peak values at 1400 h. LHβ mRNA levels were slightly elevated by progesterone at 1400 h. However, an elevation of LHβ ...
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To investigate the mechanism controlling the fall in maternal pituitary responsiveness to GnRH, LH synthesis and pituitary GnRH receptor content during pregnancy, maternal pituitaries were collected from sheep on days 35, 45, 60, 90, 110, 125 and 135 of pregnancy. Circulating steroids and gonadotrophins were determined in blood samples collected from these ewes immediately before death. Pituitary blocks from each ewe were perifused with either medium alone (control) or medium supplemented with oestradiol, oestradiol plus progesterone or oestradiol plus RU486, for 150 min before administration of two 15 s GnRH pulses 90 min apart. The amounts of mRNA encoding LHβ and GnRH receptor were determined in pituitary tissue fragments snap-frozen in liquid N2 at the time of collection from the ewes. While basal LH secretion fell during pregnancy, pituitary responsiveness to GnRH remained high (up to seven times basal LH concentrations). After day 90, the first GnRH pulse elicited LH peaks equivalent to ...
Pituitary gland produces Luteinizing Hormone (LH) - a gonadotropin hormone. LH is important for fertility, sexual health and pregnancy. It is helpful in ovulation in women and testosterone production in males. The LH test is used to measure the levels of LH in the blood.. Why is the test ordered?. The test is helpful in assessing infertility and hypogonadism, as well as in predicting ovulation and diagnosing the condition of the pituitary glands. It is also helpful in diagnosing both ovarian and testicular dysfunction. The test may be ordered in children to help diagnose early or late puberty. In women, the test may be ordered as a supportive test for assessing menstrual irregularities.. When is the test ordered?. The test may be ordered for a woman with irregular menstrual periods, or absence of periods and if she is not getting pregnant. The test may be recommended for a man if he has low testosterone and low sex drive. The test may also be recommended when pituitary disorder is suspected. A ...
TY - JOUR. T1 - Deficient melanocortin-4 receptor causes abnormal reproductive neuroendocrine profile in female mice. AU - Chen, Xiaolin. AU - Huang, Lili. AU - Tan, Hwee Y.. AU - Li, Hongzhuo. AU - Wan, Ying. AU - Cowley, Michael. AU - Veldhuis, Johannes D. AU - Chen, Chen. PY - 2017. Y1 - 2017. N2 - Deletion of the melanocortin-4-receptor (Mc4r) gene in mice causes hyperphagia, followed by hyperinsulinemia, obesity and progressive infertility. Evidence shows that the number of developed corpora lutea is reduced in obese MC4R-knockout (MC4R KO) female mice, but the mechanism is unclear. The effect of hyperphagia and obesity by MC4R KO on pulsatile luteinizing hormone (LH) secretion and ovulation remains unknown. In MC4R KO mice and wild-type littermates (WT LM) during the diestrus period throughout different ages, we examined and monitored their metabolic status, pulsatile LH profiles, follicular morphology and the number of corpora lutea. MC4R KO mice were hyperphagic, obese, hyperglycemic, ...
Semantic Scholar extracted view of [The effect of althesin-N2O anesthesia and surgery on plasma concentrations of luteinizing hormone, estradiol and progesterone in woman (authors transl)]. by Akira Maeda et al.
Postpartum interval to estrus and patterns of luteinizing hormone (LH) concentrations in first-calf suckled beef cows exposed to mature ...
Backer, L.C., Rubin, C.S., Marcus, M., Kieszak, S.M., Schober, S.E. . Serum follicle-stimulating hormone and luteinizing hormone levels in women aged 35-60 in the U.S. population: the Third National Health and Nutrition Examination Survey (NHANES III, 1988-1994) ...
en] In all mammalian females, follicular growth and maturation are essentially dependent on the pituitary gonadotropins, FSH and LH. These glycoprotein hormones have many similarities, but their action, based on high affinity binding to specific membrane receptors, are quite different. The purpose of this study was to perform a sensitive localization of FSH and LH in secretory granules of gonadotrophs using highly specific antisera. This morphological study included light microscopy (PAP) and electron microscopy (immunogold single and double labeling) procedures. Histologically, approximatively 11.5% of cells were positive for LH, whereas only 5.4% of cells were positive for FSH. With the electron microscope, single labeling allowed identification of morphologically distinct LH-containing cells and FSH-containing cells. Double immunostaining confirmed that no cells contained both hormones. The finding that FSH and LH are produced in separate pituitary cells is in agreement with recent studies ...
The LH test measures the LH blood level. This luteinizing hormone test helps evaluate fertility. Get an LH blood test near you and fast results for a low cost - Accesa Labs
Describes how the luteinizing hormone (LH) test is used, when an LH test is ordered, and what the results of an LH test might mean
I got some very stange lab results in today. Luteinizing Hormone Result |0.1 Flagged Low Units IU/L Range 1.7-8.6 FSH Serum Result 0.3 Flagged Low
Heifers experienced either a: 1) large magnitude of change in progesterone; 2) medium magnitude of change in progesterone; or 3) small magnitude of change in progesterone. During the 24 hours following the progesterone shift, heifers with the large magnitude progesterone shift had a greater LH pulse frequency than heifers with a medium or small magnitude of shift in progesterone. Despite the large or medium magnitude progesterone shift, LH pulse frequency did not differ from heifers in which a small change in progesterone occurred. We conclude that amount of progesterone in circulation is more important in regulation of LH secretion than magnitude of shift in amount of progesterone.
Small, C.J., Goubillon, M.-L., Murray, Joanne F., Siddiqui, A., Grimshaw, S.E., Young, H., Sivanesan, V., Kalamatianos, T., Kennedy, A.R., Coen, C.W., Bloom, S.R. and Wilson, C.A. (2003) Central orexin A has site-specific effects on luteinizing hormone release in female rats. Endocrinology, 144 (7). pp. 3225-3236. ISSN 0013-7227 ...
Luteinizing Hormone 小鼠单克隆抗体[L1](ab47112)可与人样本反应并经WB, ELISA实验严格验证。所有产品均提供质保服务,中国75%以上现货。
This test measures the level of luteinizing hormone in your blood. It can help figure out the cause of infertility or diagnose a pituitary disorder.
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Figure 10.5 Hypothalamic-pituitary-ovarian pathway. GnRH, gonadotrophin releasing hormone; LH, luteinising hormone; FSH, follicle stimulating hormone.. The neurons have rhythmic intrinsic depolarisation and secretory activity with g self-generated pulsatile secretion, involving short periods of abrupt secretion °. d separated by large periods of low or undetectable secretion. g. Gonadotrophin releasing hormone travels by axonomic flow to the axon g terminals of the median eminence. It binds to anterior pituitary gonadotrophs ■,. g that secrete FSH and LH. The activation mechanism is calcium-dependent ,. activation of a specific membrane receptor adenyl cyclase-cyclic AMP process. The GnRH receptor is a member of the seven transmembrane domain G-protein-coupled family of receptors.. The reproductive cycles commence at puberty as a hypothalamic pulse generator is activated and stimulates the GnRH neurons. Gonadotrophin releasing hormone simultaneously regulates FSH and LH secretion. It has a ...
岡山大学審査学位論文 Peptides Volume 76, February 2016, Pages 96-101 掲載. Author Version. [ http://dx.doi.org/10.1016/j.peptides.2016.01.011 ] © 2016. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0 ...
Islh official publication validation of the coulter lh 750 in a ... Abstract validation of the coulter lh 750 was carried out in our central hospital laboratory, which processes 1500 hemo-grams per day for patients admitted into the...(urine) one step luteinizing hormone (lh) test d=c-17 2 one step luteinizing hormone (lh) test (urine) for in vitro diagnostic use intended use one step luteinizing hormone (lh) test is a rapid...
Von turbid launched its consumer sales royally? Play games, take quizzes, print and more with Easy Notecards REPRODUCTIVE SYSTEM. Jonathon livelier fustigating his sentence thudded and desensitized! By Lara Pizzorno, MDiv, MA, LMT. Many amino acid and peptide hormones are elaborated by neural tissue, with ultimate impact on the entire system. This is done both directly on the parietal cell and. Reproduction in all species borders on the miraculous. 07. 05. Maternity Wintles Rutledge, its very hortatively beams. 03. Interstitial cell stimulating hormone; luteinizing hormone; lutropin; LH. 2017 · Follicle-stimulating hormone (FSH) is a glycoprotein gonadotropin secreted by the anterior pituitary in response to gonadotropin-releasing hormone …. Its an animal hormone and never found in plants.. 03. 2017 · Study Chapter 18 Endocrine System flashcards taken from the book Fundamentals of Anatomy and Physiology The endocrine system is the collection of glands of an organism that secrete hormones ...
What is the difference between FSH and LH? Follicle stimulating hormone (FSH) and Luteinizing hormone (LH) are commonly referred to as gonadotropins. FSH...
Clone Determination ME.116. Immunogen hLH-α subunit. Immunoglobulin Class IgG1κ. Specificity Human Luteinizing Hormone - Alpha. Purification Protein A chromatography from ascites. pI 5.0-8.0. Buffer 0.15M PBS. Preservatives None. Applications ELISA. Working dilution Determined by user. Storage Store at -20ºC to -80ºC, avoid repeat freeze-thaw cycles. FOR RESEARCH AND IN VITRO USE ONLY Contact us for bulk pricing information at 207-797-5454 or [email protected] ...
Evaluation of luteinizing hormone (LH): Validation of a business ELISA package for LH evaluation and quantification in doping management samples. Luteinizing hormone (LH) is a dimeric glycoprotein produced and secreted by the pituitary… Read more ». ...
A rise in luteinizing hormone triggers ovulation in females and testosterone in males. Since luteinizing hormone boosts hormone amounts which stimulate cell
4th Annual Oxford Symposium on Antisense and therapeutic oligonucleotides (Oligo 2018), Oxford University, Oxford, UK, 10 April 2018 ...
Assigning DOI numbers, introducing articles from supplements and recent publications to POL-index database, maintaining anti-plagiarism detection, electronic system to proceed manuscripts and webpage of the Journal with interactive pdf files, and language correction of manuscripts published in Journal of Animal and Feed Sciences are financed in the years 2018-2019 by the Ministry of Science and Higher Education from the funds for science popularization activities, Agreement No. 631/P-DUN/2018 ...
Ovulation predictor kits work by detecting the luteinizing hormone, more specifically the LH levels in your urine. Right before a woman ovulates there is a surge (increase) in the LH. The OPK detects this surge. Ovulation generally occurs within the next 36 hours after the LH surge. OPKs help you detect this surge. There are…
For the first 12 days of the menstrual cycle, estrogen has a negative effect on the production of gonadotropins. Following these 12 days the negative effect changes to a positive effect on the production of gonadotropic hormones. This results in a small increase of follicle stimulating hormone (FSH), but a large increase of luteinizing hormone (LH.) Ovulation ...
Boling et al. (1941) correlated ovulation time in rats with the interval from the beginning of heat behavior. Inasmuch as the beginning of heat in these rodents is itself related to the time of day...
Research shows that women with ovulation bleeding may have higher levels of estrogen, luteal progesterone, and luteinizing hormone (LH) around ovulation.
We observed that circulating Acrp30 levels in mice increased abruptly by the third week of postnatal life but were relatively stable thereafter. In contrast to Acrp30, circulating levels of another adipose-specific marker, leptin, are relatively constant from 1 to 6 weeks of age and only begin to rise by the seventh week (22). What triggers the rise of Acrp30 early in puberty is not known. Our results, however, indicate that it does not involve the maturation of a gonadal feedback loop because surgical excision of the testes or ovaries before puberty did not interfere with the rise of Acrp30 in adults. Marked differences between the peripubertal secretions of male and female gonads support the likelihood that the pubertal Acrp30 surge is mediated by nongonadal mechanisms, and the similar timing in the male and female Acrp30 surge suggests a common mechanism. Previous studies suggest that the peripubertal surges of growth hormone, IFG-I, prolactin, and luteinizing hormone are also triggered by ...
Luteinizing hormone (FH) and follicle stimulating hormone (FSH) are both known as gonadotropins because they stimulate the gonads in both males and females to produce steroid hormones. In males,...