TY - JOUR. T1 - Effects of the long-acting calcium channel blocker barnidipine hydrochloride on 24-h ambulatory blood pressure. T2 - Results of the Japanese Multicenter Study on Barnidipine with Ambulatory Blood Pressure Monitoring. AU - Matsuura, Hideo. AU - Imai, Yutaka. AU - Shimada, Kazuyuki. AU - Kuwajima, Iwao. AU - Abe, Keishi. PY - 2001/12/1. Y1 - 2001/12/1. N2 - The effect of barnidipine hydrochloride (barnidipine) on 24-h ambulatory blood pressure (ABP) was evaluated based on the results of Japanese Multicenter Study on Barnidipine with Ambulatory Blood Pressure Monitoring (J-MUBA). Barnidipine decreased outpatient clinic blood pressure and ABP in 387 patients, but did not affect heart rate. The patients were divided into high- and low-range groups based on ABP measurement. Barnidipine exerted an antihypertensive effect throughout the 24-h monitoring period in the high-range group, but not in the low-range group. Barnidipine had comparable effects in the daytime and night-time in ...

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TY - JOUR. T1 - Systolic Blood Pressure Response During Exercise Stress Testing. T2 - The Henry Ford ExercIse Testing (FIT) Project. AU - O'Neal, Wesley T.. AU - Qureshi, Waqas T.. AU - Blaha, Michael J.. AU - Keteyian, Steven J.. AU - Brawner, Clinton A.. AU - Al-Mallah, Mouaz H.. N1 - Publisher Copyright: © 2015 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.. PY - 2015/5/7. Y1 - 2015/5/7. N2 - BACKGROUND: The prognostic significance of modest elevations in exercise systolic blood pressure response has not been extensively examined.METHODS AND RESULTS: We examined the association between systolic blood pressure response and all-cause death and incident myocardial infarction (MI) in 44 089 (mean age 53±13 years, 45% female, 26% black) patients who underwent exercise treadmill stress testing from the Henry Ford ExercIse Testing (FIT) Project (1991-2010). Exercise systolic blood pressure response was examined as a categorical variable (,20 mm Hg: ...

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TY - JOUR. T1 - Electrocardiographic left ventricular hypertrophy and effects of antihypertensive drug therapy in hypertensive participants in the multiple risk factor intervention trial. AU - MacMahon, Stephen. AU - Collins, Gary. AU - Rautaharju, Pentti. AU - Cutler, Jeffrey. AU - Neaton, James. AU - Prineas, Ronald. AU - Crow, Richard. AU - Stamler, Jeremiah. PY - 1989/1/15. Y1 - 1989/1/15. N2 - Data are reported on electrocardiographic left ventricular hypertrophy (ECG LVH) among 8,012 men classified as hypertensive at baseline in the Multiple Risk Factor Intervention Trial. Compared with those allocated to the usual care (UC) control group, men allocated to the special intervention (SI) group experienced a mean reduction of 4 mm Hg in diastolic blood pressure and 7 mm Hg in systolic blood pressure, over 6 years of follow-up. There were 378 new cases of ECG LVH during follow-up; the incidence in the SI group was about 23% less than that in the UC group (4.2 vs 5.4% 2P , 0.01). Among the 189 ...

Ambulatory Blood Pressure Monitoring (ABPM) is a completely painless advanced technique that more accurately measures the patient's blood pressure than traditional methods. Some patients experience temporary increased blood pressure levels when they visit the doctor. Ambulatory Blood Pressure Monitoring avoids this problem. The patient performs his or her routine activities over a 24-hour period. The National Institute for Health & Care Excellence (NICE) suggests that patients with blood pressure readings of 140/90 mm Hg or higher receive ambulatory blood pressure monitoring. The process can be used to confirm the patient's hypertension. For patients with poorly-controlled hypertension and/or suspected resistance to blood pressure management medications, ABPM is a diagnostic tool. Patients who develop pregnancy-related hypertension or those considered at high-risk for complications related to hypertension benefit from ABPM. Diabetic patients or individuals with certain cerebrovascular disease, ...

White coat hypertension, more commonly known as white coat syndrome, is a phenomenon in which patients exhibit a blood pressure level above the normal range, in a clinical setting, though they don't exhibit it in other settings. It is believed that the phenomenon is due to anxiety that those afflicted experience during a clinic visit. The patient's daytime ambulatory blood pressure is used as a reference as it takes into account ordinary levels of daily stress. Many problems have been incurred in the diagnosis and treatment of white coat hypertension. The term "masked hypertension" can be used to describe the contrasting phenomenon, where a patient's blood pressure is above the normal range during daily living, although it isn't above the normal range when the patient is in a clinic setting. In studies, white coat hypertension can be defined as the presence of a defined hypertensive average blood pressure in a clinic setting, although it isn't present when the patient is at home. Diagnosis is ...

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Background: Subclinical target organ damage (TOD) has been common in hypertensive children, but there is limited data in the Chinese pediatric population. This study aimed to investigate the prevalence of subclinical TOD in the Chinese hypertensive children and adolescents.Methods: A cross-sectional study was performed in children and adolescents from four schools in Jinan, China between September 2012 and September 2014. The hypertensive status was confirmed based on elevated blood pressure across three different occasions. Those with hypertension were invited to participate in the evaluation of TOD (including heart, arteries, and kidney) and metabolic disorders. A total of 7,840 children and adolescents aged 6-17 years were recruited at baseline, of whom 373 were diagnosed as hypertensive after three separate visits, and 333 (89%) participated in evaluation of TOD.Results: Among 333 hypertensive children, 47.4% had elevated carotid intima-media thickness, 32.4% had left ventricular hypertrophy, 29.2%

Define compartment pressure. compartment pressure synonyms, compartment pressure pronunciation, compartment pressure translation, English dictionary definition of compartment pressure. Noun 1. compartment pressure - the air pressure maintained in an air-tight compartment air pressure, atmospheric pressure, pressure - the pressure exerted...

Jean, F., Aubert, A., Bloch, F., Petite, J. P., Priollet, P., Fiessinger, J. N., Husson, J. M. and Billaud, E. (1986), Effects of diltiazem versus nifedipine on lower esophageal sphincter pressure in patients with progressive systemic sclerosis. Arthritis & Rheumatism, 29: 1054-1055. doi: 10.1002/art.1780290821 ...

Keywords: Caffeine; heart rate variability; healthy volunteers. Introduction. The caffeine is one of the most widely used pharmacologically active substances. It has many different physiological effects on the cardiovascular function. Also the cardiac autonomic control could be altered by caffeine consumption. However, findings regarding the effect of caffeine consumption on cardiac autonomic nervous system (ANS) activity are controversial. The aim of the present study was to assess the effects of caffeine on cardiac ANS in young healthy subjects. Methods and Materials. In sixteen healthy volunteers (7 women), age 24-35, the electrocardiogram (ECG) was recorded continuously at rest before as well as 30 min and 60 min after caffeine ingestion (200 mg of caffeine in 50 ml of water). Before each the beginning of ECG registration the arterial blood pressure was measured. As assessment of cardiac ANS activity the power spectral analysis (autoregressive spectra) and the Poincaré plot analysis of the ...

The combination of benazepril plus amlodipine was shown to be more effective than benazepril plus hydrochlorothiazide in reducing cardiovascular events in the Avoiding Cardiovascular Events through Combination Therapy in Patients Living with Systolic Hypertension (ACCOMPLISH) trial. There was a small difference in clinic systolic blood pressure between the treatment arms favoring benazepril plus amlodipine. Ambulatory blood pressure monitoring provides a more rigorous estimate of blood pressure effects. A subset of 573 subjects underwent ambulatory blood pressure monitoring during year 2. Readings were obtained every 20 minutes during a 24-hour period. Between-treatment differences (benazepril plus amlodipine versus benazepril plus hydrochlorothiazide) in mean values were analyzed using ANOVA. Treatment comparisons with respect to categorical variables were made using Pearson's χ2. At year 2, the treatment groups did not differ significantly in 24-hour mean daytime or nighttime blood pressures ...

TY - JOUR. T1 - Role of paraventricular nucleus (PVH) in baroreflex-mediated changes in lumbar sympathetic nerve activity and heart rate. AU - Patel, K. P.. AU - Schmid, P. G.. PY - 1988/4. Y1 - 1988/4. N2 - Electrophysiological and neuronanatomical studies indicate that reciprocal connections between the paraventricular nucleus (PVH) and medullary sites are involved in cardiovascular regulation. To determine whether the PVH is involved in the regulation of baroreflex responses, lumbar sympathetic nerve activity (LSNA) and heart rate (HR) changes were recorded in response to increases in arterial pressure (produced by bolus doses of phenylephrine i.v.) prior to, during, and 60 min following the injection of lidocaine (2% lidocaine, 200 nl) bilaterally in the PVH of chloralose-anesthetized rabbits. Baseline blood pressure, HR, and LSNA did not change in response to the administration of lidocaine in the PVH. The magnitude of 'baroreflex responses' in HR and LSNA were expressed as the ratios of ...

0031] Referring to FIG. 6, in virtue of the ball-specific recommended pressure dial 60, a user reading the reading pointed by the air-pressure indicator 40 can at the same time be informed of whether the air pressure inside the ball 90 is appropriate for the particular ball. If the measured air pressure inside the ball 90 is lower than the recommended range for that ball, inflation can be conducted again to raise the air pressure inside the ball 90. If the air pressure inside the ball 90 is greater than the recommended range, the pressure-resealing valve 30 can be operated to allow the air inside the ball 90 to communicate with the external, ambient atmosphere through the probe 20, thereby releasing some air to reduce the air pressure inside the ball 90. Then, when the air-pressure indicator 40 points the air pressure as one applicable to the ball, the pressure-resealing valve 30 can be closed, so the adjustment of air pressure inside the ball 90 is completed ...

Arterial baroreflex and cardiac autonomic control play important roles in hemodynamic instability after carotid artery stenting (CAS). Spontaneous baroreflex sensitivity (BRS), heart rate variability (HRV) and blood pressure variability (BPV) are established tools for the assessment of arterial baroreflex and cardiac autonomic activity. Aim of the study was to evaluate cardiac autonomic activity (by means of HRV, BPV and BRS) after CAS and to explore the impact of internal carotid artery stenosis on BRS changes after CAS. 37 patients (68±10.45 years) with internal carotid stenosis underwent CAS. HRV, BPV and BRS were measured in all subjects before and at 1 and 72h after CAS. ANOVA was performed to compare BRS, HRV and BPV parameters before and after CAS. Spearman analysis was performed to determine a possible correlation between carotid stenosis degree (or carotid plaque diameter) and BRS changes (ΔBRS). LF/HF (index of sympatho-vagal balance) decreased during postoperative period, in ...

Keeping track of your blood pressure is an important aspect in living a healthy life. It can be done at home or at health center. Getting your own blood pressure monitor gives you the convenience of checking blood pressure at any time. Checking your blood pressure helps in preventing high blood pressure by detecting it early enough before anything catastrophic happens.. The number of blood pressure monitors in the market is enormous, getting the best can be a really daunting task. I took the liberty of looking for the Top 10 Best Blood Pressure Monitors Reviews from rankerreview.com, with the aim of choosing the best of the best. I first broke down the factors that are essential in a blood pressure monitor, I then went to the extras that came with the shortlisted blood pressure monitor. ...

TY - JOUR. T1 - Tracking central hypovolemia with ECG in humans. T2 - Cautions for the use of heart period variability in patient monitoring. AU - Ryan, Kathy L.. AU - Rickards, Caroline A.. AU - Ludwig, David A.. AU - Convertino, Victor A.. PY - 2010/6/1. Y1 - 2010/6/1. N2 - Heart period variability (HPV) metrics have been suggested for use in medical monitoring of trauma patients. This study sought to ascertain the use of various HPV metrics in tracking central blood volume during simulated hemorrhage in individual humans. One hundred one healthy nonsmoking volunteers (58 men, 43 women) were instrumented for continuous measurement of electrocardiogram and beat-by-beat finger arterial blood pressure. Stroke volume (SV) was estimated from the arterial pulse wave and used to reflect central blood volume. Progressive lower body negative pressure (LBNP) was applied in 5-min stages until the onset of impending hemodynamic decompensation (systolic blood pressure ,70 mmHg and/or presyncopal symptoms). ...

An ambulatory blood pressure monitor is a small device that you wear throughout the day, usually for 24 or 48 hours. The device takes your blood pressure automatically while you do your normal daily activities.. The device periodically inflates and takes blood pressure measurements, which are recorded for later printout and analysis. The devices are usually loaned by a clinic, hospital, or pharmacy.. Your doctor might ask you to use one of these monitors after measuring your blood pressure in the doctor's office, to make sure that you actually have high blood pressure. This is because your blood pressure can change during the day. And sometimes blood pressure is higher only because you are seeing a doctor. This is called white-coat hypertension. To diagnose high blood pressure, your doctor needs to know if your blood pressure stays high throughout the day. If you are required to use an ambulatory blood pressure monitor, keep in mind that it is important for a health professional to properly size ...

Cricoid pressure is considered to be the gold standard means of preventing aspiration of gastric content during Rapid Sequence Intubation (RSI). Its effectiveness has only been demonstrated in cadaveric studies and case reports. No randomised controlled trials comparing the incidence of gastric aspiration following emergent RSI, with or without cricoid pressure, have been performed. If improperly applied, cricoid pressure increases risk to the patient. The clinical significance of aspiration in the emergency department is unknown. This randomised controlled trial aims to; 1. Compare the application of the 'ideal' amount of force (30 - 40 newtons) to standard, unmeasured cricoid pressure and 2. Determine the incidence of clinically defined aspiration syndromes following RSI using a fibrinogen degradation assay previously described. 212 patients requiring emergency intubation will be randomly allocated to either control (unmeasured cricoid pressure) or intervention groups (30 - 40 newtons cricoid pressure

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TY - JOUR. T1 - The effect of anti-hypertensive drugs on DNA synthesis and proliferation of cultured rat aortic smooth muscle cells. AU - Kang, Shin Wook. AU - Lee, In Hee. AU - Choi, Kyu Hun. AU - Lee, Ho Yung. AU - Han, Dae Suk. PY - 1997. Y1 - 1997. N2 - The aim of this study was to elucidate the effects of anti-hypertensive drugs, nifedipine, furosemide, hydrochlorothiazide, captopril, and atenolol on DNA synthesis and proliferation of cultured rat aortic smooth muscle cells induced by fetal calf serum. Aortic smooth muscle cells from Sprague-Dawley rats were isolated, cultured, and seeded in multi-well plates. When confluent, cells were cultured in a conditioned medium without fetal calf serum. After 72 hours, cells were cultured in the medium retaining 10% fetal calf serum with or without anti-hypertensive drugs by increasing the concentration between 10-8 and 10-4M. DNA synthesis was assessed by [3H]-thymidine uptake and proliferation by cell numbers using a hemocytometer. Nifedipine at a ...

TY - JOUR. T1 - The impact of continuous positive airway pressure on the lower esophageal sphincter. AU - Shepherd, K.. AU - Holloway, R.. AU - Hillman, D.R.. AU - Eastwood, Peter. PY - 2007. Y1 - 2007. N2 - The lower esophageal sphincter ( LES) is the primary barrier to gastroesophageal reflux. Reflux is associated with periods of LES relaxation, as occurs during swallowing. Continuous positive airway pressure ( CPAP) has been shown to reduce reflux in individuals with and without sleep apnea, by an unknown mechanism. The aim of this study was to determine the effect of CPAP on swallow- induced LES relaxation. Measurements were made in 10 healthy, awake, supine individuals. Esophageal ( Pes), LES ( Ples), gastric ( Pg), and barrier pressure to reflux ( Pb = Ples - Pg) were recorded using a sleeve catheter during five swallows of 5 ml of water. This was repeated at four levels of CPAP ( 0, 5, 10, and 15 cmH(2)O). Pressures were measured during quiet breathing and during the LES relaxation ...

We do not encounter abdominal compartment syndrome often in the emergency department. With that said, this diagnosis enters our differential from time to time. Consider the patient with an active arterial bleed from a liver mass with large hemoperitoneum who is transferred from an outside institution for IR embolization. His abdomen is rock solid, and his lactate is 10. While you address his hemorrhagic shock, you have to at least consider the possibility of abdominal compartment syndrome. This is a case I was involved in several months ago; IR emergently drained his hemoperitoneum given the concern for abdominal compartment syndrome.. Abdominal compartment syndrome results from a sustained increase in intraabdominal pressure. The resulting decreased perfusion pressure to the viscera leads to ischemia and organ failure. While more common in post surgical patients in the ICU, this is a diagnosis the emergency physician should be familiar with.. Risk factors in ED population (this is far from a ...

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Premature ventricular contractions is one of the most common symptomatic arrhythmia. Antiarrhythmia drugs for premature ventricular contractions, such as beta-blockers and sodium channel blockers, can cause bradycardia. For sinus bradycardia patients complicated with premature ventricular contractions, it's hard for doctors to make decision. The purpose of the study is to assess the effects of Chinese medicine Shansong Yangxin capsule for sinus bradycardia complicated with ventricular premature beats, which based on the numbers of premature ventricular contractions and average hear rate in 24-hour ambulatory electrocardiogram (ECG) after 8 weeks treatment as the primary endpoint of the study. Secondary endpoints are evaluation of the Shensong Yangxin capsule on quality of life. This study is a randomized, double-blind, placebo controlled, multi-center trial. Sinus bradycardia patients(average heart rate 45-59 beat per minute) associated with premature ventricular contractions (PVC number ,10000 ...

TY - JOUR. T1 - Power spectral and time based analysis of heart rate variability following 15 days head-down bed rest. AU - Crandall, C. G.. AU - Engelke, K. A.. AU - Pawelczyk, James Anthony. AU - Raven, P. B.. AU - Convertino, V. A.. PY - 1994/1/1. Y1 - 1994/1/1. N2 - Power spectral and time based analyses were applied to the cardiac inter- beat interval (RRI) of 8 healthy men before and after 15 d of bed rest in the 6° head-down tilt position (HDT) to determine changes in indices of cardiac parasympathetic and sympathetic activity after this exposure. At 24 h prior to HDT and on MDT day 15, a minimum of 256 RRI's were obtained from an electrocardiogram (ECG) while the subjects were in the supine position. RRI was subjected to power spectral and two methods of time-based analyses. Power spectral and two methods of time-based analyses. Power spectral analysis demonstrated that the index of cardiac vagal activity was reduced (95.2 ± 28.5 to 48.2 ± 17.4 ms2) without affecting the index of ...

TY - JOUR. T1 - Benazepril combined with either amlodipine or hydrochlorothiazide is more effective than monotherapy for blood pressure control and prevention of end-organ injury in hypertensive Dahl rats. AU - Zhou, Ming Sheng. AU - Jaimes, Edgar A.. AU - Raij, Leopoldo. N1 - Copyright: Copyright 2008 Elsevier B.V., All rights reserved.. PY - 2006/7. Y1 - 2006/7. N2 - We studied the effect of hydrochlorothiazide (HCTZ), the angiotensin-converting enzyme inhibitor benazepril, the calcium channel blocker amlodipine, or a combination of benazepril/amlodipine or benazepril/HCTZ on systolic blood pressure (BP) and end-organ injury (left ventricular hypertrophy, proteinuria, and endothelium-dependent relaxation to acetylcholine) in hypertensive Dahl salt-sensitive rats fed either a normal-salt (0.5% NaCl) or high-salt (4% NaCl) diet for 6 weeks. Rats fed a high-salt diet developed hypertension and significant end-organ injury. Monotherapy with HCTZ (75 mg/L in drinking water) or amlodipine (10 ...

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Intermittent pneumatic compression devices combined with anticoagulants for prevention of symptomatic deep vein thrombosis after total knee arthroplasty: a pilot study Pengcheng Liu,* Junfeng Liu,* Liyang Chen, Kuo Xia, Xing Wu Department of Orthopedics, Shanghai Tenth People’s Hospital, School of Medicine, Tongji University, Shanghai, People’s Republic of China *These authors contributed equally to this work Objectives: To investigate the effectiveness of intermittent pneumatic compression (IPC) devices combined with anticoagulants for the prevention of deep vein thrombosis (DVT) after total knee arthroplasty (TKA). Patients and methods: In total 120 patients were involved in this pilot study. Patients in the control group received 10 mg of rivaroxaban per day after surgery. In addition to the prescription of rivaroxaban, IPC devices were used in the experimental group. The diagnosis of DVT was made by compression duplex ultrasound on postoperative day 9. Results: The incidence rates of

The double peak profile, or unreduced hernia, was present for 626 minutes. In all patients, both pressure profiles were observed. The transition rate between the 2 profiles was 8 per hour. The team noted that more reflux occurred when the lower esophageal sphincter and diaphragm were separated versus the reduced hernia state. The researchers found that the proportions of acidic reflux episodes during the single and double pressure peaks were similar. In the 2-pressure-zone state, there was an increase in all reflux mechanisms except transient lower esophageal sphincter relaxation. Dr Bredenoord's team concluded, In patients with a small hiatal hernia, intermittent reduction of the hernia occurs frequently. Spatial separation of the diaphragm and lower esophageal sphincter in the nonreduced state results in a 2-fold increase in acidic and weakly acidic reflux due to mechanisms other than transient lower esophageal sphincter relaxation. ...

All articles relevant to the topic were identified via a comprehensive literature search. The following databases were searched: PubMed, Google Scholar, MEDLINE, Cumulative Index to Nursing and Allied Health (CINAHL), Cochrane Library, Agency for Healthcare Research and Quality (AHRQ; www.ahrq.gov), and the National Guideline Clearinghouse (www.guideline.gov). Searches were conducted using a variety of different search combinations of key words including blood pressure, blood pressure measurements, automated blood pressure, oscillometric blood pressure, auscultatory blood pressure, alternative cuff sites for blood pressure measurements, monitoring blood pressure, intermittent blood pressure, non-invasive blood pressure measurement, blood pressure monitoring, and effect of clothing on blood pressure measurement. Initial searches were limited to English language articles from January 1990 to November 2012. In addition, the reference lists in the selected articles were scanned for additional ...

The importance of counterregulatory mechanisms triggered by arterial vasodilation for the antihypertensive response to the calcium entry blocking agent nifedipine was investigated in 13 men with mild to moderate essential hypertension. Blood pressure and systemic vascular resistance were significantly reduced 30 minutes after sublingual administration of 10 mg of nifedipine while heart rate, cardiac index and plasma norepinephrine concentrations increased (all p , 0.01). Also, changes in mean blood pressure correlated inversely with arterial baroreflex sensitivity (r = -0.74, p , 0.01), suggesting that arterial baroreflex mechanisms by means of sympathetic activation tend to limit the acute antihypertensive response. Blood pressure, but not systemic vascular resistance, decreased further (p , 0.01) after 6 weeks of therapy with nifedipine 20 mg three times daily, while average heart rate, cardiac index and plasma norepinephrine concentrations had returned toward pretreatment values.. Thus, a ...

TY - JOUR. T1 - Both central command and exercise pressor reflex activate cardiac sympathetic nerve activity in decerebrate cats. AU - Tsuchimochi, Hirotsugu. AU - Hayes, Shawn G.. AU - McCord, Jennifer L.. AU - Kaufman, Marc P. PY - 2009/4. Y1 - 2009/4. N2 - Both static and dynamic exercise are known to increase cardiac pump function as well as arterial blood pressure. Feedforward control by central command and feedback control by the exercise pressor reflex are thought to be the neural mechanisms causing these effects during exercise. It remains unknown as to how each mechanism activates cardiac sympathetic nerve activity (CSNA) during exercise, especially at its onset. Thus we examined the response of CSNA to stimulation of the mesencephalic locomotor region (MLR, i.e., central command) and to static muscle contraction of the triceps surae muscles or stretch of the calcaneal tendon in decerebrate cats. We found that MLR stimulation immediately increased CSNA, which was followed by a gradual ...

TY - JOUR. T1 - Aldosterone-to-renin ratio and nocturnal blood pressure decline assessed by self-measurement of blood pressure at home. T2 - The Ohasama Study. AU - Satoh, Michihiro. AU - Hosaka, Miki. AU - Asayama, Kei. AU - Kikuya, Masahiro. AU - Inoue, Ryusuke. AU - Metoki, Hirohito. AU - Utsugi, Megumi T.. AU - Hara, Azusa. AU - Hirose, Takuo. AU - Obara, Taku. AU - Mori, Takefumi. AU - Totsune, Kazuhito. AU - Hoshi, Haruhisa. AU - Mano, Nariyasu. AU - Imai, Yutaka. AU - Ohkubo, Takayoshi. N1 - Funding Information: None of the authors declare a conflict of interest. This work was supported by Grants for Scientific Research (23249036, 23390171, 24591060, 24390084, 24591060, 24790654, 25461205, 25461083, 25860156 and 25253059) from the Ministry of Education, Culture, Sports, Science, and Technology, Japan; Grants-in-Aid for Japan Society for the Promotion of Science (JSPS) fellows (25.9328 and 25.7756); a Health Labor Sciences Research Grant (H23-Junkankitou [Seishuu]-Ippan-005) from the ...

Background: Left ventricular end diastolic pressure could be estimated collectively using various measures of mitral valve and pulmonary venous flow velocities. In patients with aortic regurgitation, the AR velocity reflects the diastolic pressure difference between the aorta and the left ventricle. We sought to predict the left ventricular end diastolic pressure by a new Doppler index as aortic regurgitation peak early to late diastolic pressure gradient ratio.Patients and Methods: Fifty three patients with at least moderate aortic regurgitation were enrolled in this study. Physical examination, electrocardiography and echocardiography were performed one day before cardiac catheterization. The severity of AR was graded according to the recommendations of American society for echocardiography. The pressure half time, aortic regurgitation early diastolic velocity , aortic regurgitation early diastolic pressure gradient , aortic regurgitation end diastolic velocity, aortic regurgitation end diastolic

Monitoring your blood pressure at home used to be a rather tricky prospect for many people. Those who had arthritis couldn't squeeze the bulb used to pump up the pressure cuff, and those with hearing loss couldn't hear the heart sounds through the stethoscope. Even those with no physical problems had to learn the proper rate of cuff deflation and how to distinguish subtle heart sounds. Today, however, all of those problems have been solved by the development of digital monitors.. If you're using a fully automatic digital blood pressure monitor, all you have to do is position it on your arm and push a button. The cuff inflates and deflates automatically at the proper rate. Since the blood pressure is measured by an oscilloscope, there's no need to listen for heart sounds. The systolic and diastolic numbers are displayed on a small screen. Pulse rate is usually displayed as well. A semiautomatic digital monitor does everything except inflate the pressure cuff. Digital blood pressure monitors are ...

The aim of present study was to evaluate relationships between degree of portal hypertension, severity of the disease, and bleeding status in patients with liver cirrhosis. Patients and methods. All study patients with liver cirrhosis underwent hepatic venous pressure gradient measurements, endoscopy, clinical and biochemical evaluation. Liver function was evaluated according to Child-Turcotte-Pugh (Child's) scoring system. Patients with decompensated cirrhosis (presence of severe ascites, acute variceal bleeding occurring within 14 days, hepatorenal syndrome, cardiopulmonary disorders, transaminase levels >10 times higher the upper normal limit), active alcohol intake, use of antiviral therapy and/or beta-blockers were excluded from the study. Results. One hundred twenty-eight patients with liver cirrhosis (male/female, 67/61; mean age, 53.8±12.7 years) were included into the study. Etiology of cirrhosis was viral hepatitis, alcoholic liver disease, cryptogenic and miscellaneous reasons in 57, 49,

It is often used in high blood pressure. Losartan 50 mg once daily for four weeks, followed by losartan … Summary: We compare the side effects and drug effectiveness of Olmesartan medoxomil and Losartan potassium. Systolic and diastolic blood pressure readings taken in the final 2, 4, and 6 hours of the 24-hour ABPM cycle are summarized. Olmesartan medoxomil; hydrochlorothiazide has active ingredients of olmesartan … In week 4, participants arrived at the site in the morning without having taken that day's dose of medication. Change From Baseline in Mean Daytime (8am to 4pm) and Mean Nighttime (10pm to 6am) Ambulatory Blood Pressure at Week 8. Cozaar (losartan) is available in the following dosages: 25 mg; 50 mg; 100 mg; As you can see, Benicar (olmesartan) is a more potent drug, on a milligram basis, than Cozaar (losartan). Olmesartan is better than losartan at lowering blood pressure and generally provides good 24-hour coverage. Treatment as a fixed effect and the seated cuff diastolic blood

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