A newborn black boy had two facial blisters at birth that progressed to bullous lesions over the trunk, genitals, extremities, and oral and tracheal mucosa. A biopsy specimen demonstrated a subepidermal bulla with mixed eosinophilic and neutrophilic, inflammatory infiltrate. Direct immunofluorescence showed linear IgA, IgG, and C3 depositions along the basement membrane zone, consistent with a diagnosis of childhood linear IgA bullous dermatosis (chronic bullous dermatosis of childhood). The skin disease was controlled with combined prednisone and dapsone. This is the youngest reported patient with the disease. Linear IgA bullous dermatosis should be considered in the differential diagnosis of blistering diseases of the newborn, and immunofluorescence should be performed on a skin biopsy specimen ...

A 16-day-old boy was admitted to our clinic with localized blisters on the neck, cheeks, earlobes, and oral cavity and with erythema on the toes, in addition to

I too get this reaction with water as well as from shaving. Do you get it in the ocean? My skin really reacts to the salt water. I am usually itchy after a shower. I am trying a rice protein soap (no wheat or gluten)-- it is actually a shampoo but I have been using it as a soap too and I havent been itchy the last few showers. The other night I used gillette shaving gel and a new blade along with only the rice shampoo. All was ok. I did not use cream no matter how much my skin needs it. I think usually when I shave I get soap on my legs that must contain something in it that bothers me. I have yet to find a cream that will soothe it, most make it worse. I get itchy bumps and everywhere I scratch the lines are red and raised. Lovely. I have been told the causes are Dermatic Graphism, seborreah (spelling?), linear iga bullous dermatosis (blistering disease), foliculitis, hypothyroidism (this can make your skin dry and itchy I am told) etc. I do not take meds for any of these conditions as I am ...

Diagnosis Code 694.8 information, including descriptions, synonyms, code edits, ICD-10 conversion and references to the diseases index.

DISCUSSION In this report a case of SEBD associated with keratoconjunctivitis and severe facial scarring in a dog and its successful treatment with prednisone and MMF as steroid sparing agent is described. After slowly tapering prednisone, over 6 months, to a very low dose on alternate days, the skin lesions remained well controlled for another 10 months when the dog was lost to follow-up. During that time, prednisone therapy could probably have been discontinued if the keratoconjuctivitis, which was of much concern to the owner, had responded to its specific treatment or if clinical signs of iatrogenic hyperadrenocorticism had been present. Clinical differential diagnoses for SEBD in the dog include BP, MMP, EBA, linear IgA dermatosis and bullous drug eruptions6. Precise differentiation among these dermatoses requires demonstration of circulating autoantibodies and their targeted antigens in the basement membrane zone. Other vesiculobullous dermatosis such as pemphigus foliaceus, pemphigus ...

The presentation is similar to that seen in classic linear IgA disease: a vesiculobullous eruption affecting the trunk, inner thighs and pelvic area ...

Takashi Haneda, Yasutomo Imai, Hiroshi Koga, Takashi Hashimoto and Kiyofumi Yamanishi Case of subepidermal bullous dermatosis with immunoglobulin G autoantibodies against various basement membrane zone proteins The Journal of Dermatology 40. Version of Record online: 21 JAN 2013 , DOI: 10.1111/1346-8138.12079. Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf. Required = Required Field. ...

What are the aims of this leaflet?. This leaflet has been written to help you understand more about Linear IgA disease. It tells you what it is, what causes it, what can be done about it, and where you can find out more about it.. What is Linear IgA disease?. Linear IgA disease is a very rare blistering condition of the skin in adults. A similar condition affecting children is known as Chronic Bullous Disease of Childhood (CBDC).. The condition is called Linear IgA disease because a type of protein called immunoglobulin A (IgA) can be seen deposited under the outer layer of the skin (the epidermis) in a line (linear) when a small sample of skin biopsy is prepared specially and examined under the microscope.. What causes Linear IgA disease?. Often no cause can be identified. Sometimes, infections and occasionally medicines may trigger linear IgA disease. The disease is thought to be related to the immune system (IgA protein) attacking structures in the skin layers (i.e. it is an autoimmune ...

Linear IgA disease (LAD) is an acquired autoimmune subepidermal bullous disease characterized by the linear deposition of IgA at the basement membrane zone. A minority of cases are induced by drugs, of which the most frequently implicated is vancomycin. The target antigens in idiopathic LAD are heterogeneous, but have not previously been reported in vancomycin-induced LAD. We report three cases, and in two of these we investigated the target antigens. In both we identified IgA antibodies to LAD285 and IgA and IgG antibodies (dual response) to BP180.

Bullous dermatoses can be debilitating and possibly fatal. A selection of autoimmune blistering diseases, including pemphigus vulgaris, paraneoplastic pemphigus, bullous pemphigoid, cicatricial pemphigoid, dermatitis herpetiformis and linear IgA dermatosis are reviewed. Pemphigus vulgaris usually starts in the oral mucosa followed by blistering of the skin, which is often painful. Paraneoplastic pemphigus is associated with neoplasms, most commonly of lymphoid tissue, but also Waldenströms macroglobulinemia, sarcomas, thymomas and Castlemans disease. Bullous pemphigoid is characterized by large, tense bullae, but may begin as an urticarial eruption. Cicatricial (scarring) pemphigoid presents with severe, erosive lesions of the mucous membranes with skin involvement in one third of patients focused around the head and upper trunk. Dermatitis herpetiformis is intensely pruritic and chronic, characterized by papulovesicles and urticarial wheals on the extensor surfaces in a grouped or herpetiform,

We describe a case of fatal systemic amyloidosis presenting with mucocutaneous bullous lesions in a patient with IgA κ monoclonal gammopathy. The amyloid plaques were composed of an unusual mixture of immunoglobulin κ light chain and amyloid A proteins. Whereas oesophageal and oropharyngeal blisters are known to occur in several types of bullous dermatoses, to our knowledge this is the first report of oesophagopharyngeal blisters complicating bullous amyloidosis ...

Dermatosis is any condition affecting the skin, nails, skin glands or hair according to Healthline. Dermatosis does not include inflammation, as inflammation of those areas is called...

Общественная организация Всеукраїнська Правова країна создана для защиты прав и свобод граждан Украины

Basic principles of dermatology -- Anatomy and physiology -- Skin development and maintenance -- Molecular biology -- Immunology -- Cutaneous neurophysiology -- Pruritus and dysesthesia -- Psychocutaneous diseases -- Psoriasis -- Other papulosquamous disorders -- Erythroderma -- Lichen planus and lichenoid dermatoses -- Atopic dermatitis -- Other eczematous eruptions -- Allergic contact dermatitis -- Irritant contact dermatitis -- Occupational dermatoses -- Dermatoses due to plants -- Urticaria and angioedema -- Figurate erythemas -- Erythema multiforme, stevens-johnson syndrome, and toxic epidermal necrolysis -- Drug reactions -- Purpura : mechanisms and differential diagnosis -- Cutaneous manifestations of microvascular occlusion syndromes -- Cutaneous vasculitis -- Eosinophil-associated dermatoses -- Neutrophilic dermatoses -- Pregnancy dermatoses -- The biology of the basement membrane -- Pemphigus -- Pemphigoid group -- Dermatitis herpetiformis and linear IgA bullous dermatosis -- ...

Epidermal necrolysis (EN) encompasses Stevens-Johnson syndrome (SJS, | 10% of the skin affected), Lyell syndrome (toxic epidermal necrolysis, TEN, with ≥30% of the skin affected) and an overlap syndrome (10 to 29% of the skin affected). These rare diseases are caused, in 85% of cases, by pharmacological treatments, with symptoms occurring 4 to 28 days after treatment initiation. Mortality is 20 to 25% during the acute phase, and almost all patients display disabling sequelae (mostly ocular impairment and psychological distress). The objective of this French national diagnosis and care protocol (protocole national de diagnostic et de soins; PNDS), based on a critical literature review and on a multidisciplinary expert consensus, is to provide health professionals with an explanation of the optimal management and care of patients with EN. This PNDS, written by the French National Reference Center for Toxic Bullous Dermatoses was updated in 2017 ( https://www.has-sante.fr/portail/jcms/c

Vesiculopustular dermatoses refers to serum filled blisters and pus filled bumps in various areas. While many times the exact trigger of vesiculopustular dermatoses are unknown, there are some underlying diseases that may lead to the condition. - Wag! (formerly Vetary)

Papulonodular dermatoses are part of a group of skin conditions that cause small, hard bumps called papules and nodules. They can cause severe itching, which in turn can lead to other serious side ...

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In this article, Dr Mitesh Patel and Mr David Nunns look at the manifestations of, and treatments for, numerous non-cancerous vulval dermatoses

Drug = ALXN1830; ARGX-113; Acetaminophen; Acetaminophen/paracetamol; Acetate; Antihistamine (cetirizine or equivalent); Azathioprine; CELLCEPT®; CORTANCYL 20 mg; Carboxymethylcellulose; CellCept 500 mg comprimidos recubiertos; CellCept®500 mg comprimidos; Cellcept® in autoimmune bullous dermatoses; Cellulose; Cetirizine; Cohort 1: 1.0 x 10^8 PolyTregs; Cohort 2: 2.5x10^8 PolyTregs; Combination of Protein A Immunoadsorption, Rituximab, Dexamethasone plus Azathioprine; Cortancyl; Corticosteroidstherapy; Cotton; Cyclophosphamide; DSG3-CAART; Dapsone; Dermoval; Device: Carboxymethylcellulose with ionic silver (Aquacel Ag); Device: Cellulose acetate with petrolatum; Device: Cotton gauze with petrolatum; Device: Nanocrystalline silver (Acticoat); Dexamethasone; Dexamethasone (50mg 1dd6, 3 consecutive days/month); Dexamethasone 0.5mg/5ml solution; Dexamethasone 0.5mg/5ml solution in Mucolox™; EFGARTIGIMOD ALFA; Efgartigimod; Efgartigimod PH20 SC; Efgartigimod alfa; Enbrel (Etanercept); ...

My dad is 73 and had a total colectomy 2.5 months ago and has an ileostomy bag. This week he has had daily bouts of bloody mucus discharged from his rectum, usually when hes peeing. Theres nothing ...

A study to analyze the correlation between nutritional dermatoses with socioeconomic status, dietary fallacies and growth in children 1 to 5 years of age, in and around rural area

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Vitamin A Responsive Dermatosis - Transmission or Cause: Vitamin A-responsive dermatosis is an incompletely understood disorder of skin proliferation and maturation (keratinization) which

Skin care small dog es un alimento dietético completo para perros adultos de razas pequeñas, formulado para mantener la función dérmica en caso de dermatosis y pérdida excesiva de pelo. este alimento contiene un alto nivel de ácidos grasos esenciales. ...

Subcorneal pustular dermatosis was first described by Sneddon and Wilkinson in 1956. It is a rare, benign, chronic relapsing sterile pustular eruption typically involving the flexural sites of the trunk and proximal extremities.

The dermatoses of pregnancy are a heterogeneous group of pruritic inflammatory dermatoses that occur exclusively during pregnancy and/or in the immediate postpartum period. These include the following conditions, which are discussed below:Pemphigoid

Pyogenic dermatosis,The pathogenic bacteria is Streptococcus pyogenes and Staphylococcus aureus, which is a common disease. The incidence of the disease is high

Hi. Chrons Ma back after a long hiatus, still in the role of caring for my son, now 24. Sadly, a total colectomy last June following a sustained period of...