Adverse life events have been shown to predict weight fluctuations and dietary restraint, as well as eating disorders during adolescence or early adulthood. Since the s-allele carriers of the 5-HTT gene-linked polymorphic region (5-HTTLPR) are biologically more reactive to stress related stimuli, we aimed to explore whether the eating disturbances are predicted by environmental stressors and moderated by the 5-HTTLPR genotype. The sample was based on the younger cohort of the Estonian Children Personality, Behaviour and Health Study and included those participating in its second and third wave. The history of stressful life events was self-reported at age 15. Data on eating behaviour and attitudes, anxiety, impulsivity and depressiveness were collected at age 18. The effect of the adverse life events on binge eating and on drive for thinness was found to be moderated by the 5-HTTLPR. Adolescent girls who at age 15 had reported a history of frequent adverse life events had elevated scores in ...
The study investigated the frequency of adverse life events and prevalence of MD recorded for clients with intellectual disabilities (ID) in a medium secure unit, using data from an electronic patient record (EPR) system. Prevalence of MD was calculated on the basis of ICD-10 diagnoses and a 38-item checklist was developed to investigate adverse/traumatic life events for sub-samples with and without MD. High rates of MD were reported overall, particularly of schizotypal and delusional disorders and disorders of personality. Adverse life events including abuse, bereavement and relationship difficulties had been documented by clinicians. The overall number of recorded events was significantly higher for clients diagnosed with a MD. Associations between MD and life events have been reported previously, but not in a forensic ID population. The study contributes to a growing body of literature highlighting the relationship between life events and mental health in people with ID, offering further ...
Although the limited size of the buffering effect may not be considered important in clinical settings, from a population health perspective the findings represent an additional small but significant piece of the puzzle in the pursuit to understand the determinants of population health. It is worth noting that the effect of experiencing a RLE on SRH seems to be completely mitigated or tempered in people with above average SOC. Additionally, it is plausible that much larger effects could be found if the outcomes examined were more proximal to the experience of stressful life events. For example, SOC might buffer the perceived stress, autonomic nervous system dysregulation, or neuroendocrine response associated with the experience of stressful life events to a much greater extent than was seen with the measure of SRH. Furthermore, the analysis in this study relied on a dichotomised derived index of various RLEs; it is possible that some stressful life events may be buffered to a greater or lesser ...
TY - JOUR. T1 - Development and assessment of stressful life events subscales - A preliminary analysis. AU - Buccheri,Teresa. AU - Musaad,Salma. AU - Bost,Kelly K.. AU - Fiese,Barbara H.. AU - the STRONG Kids Research Team. PY - 2018/1/15. Y1 - 2018/1/15. N2 - Background Stress affects people of all ages, genders, and cultures and is associated with physical and psychological complications. Stressful life events are an important research focus and a psychometrically valid measure could provide useful clinical information. The purpose of the study was to develop a reliable and valid measurement of stressful life events and to assess its reliability and validity using established measures of social support, stress, depression, anxiety and maternal and child health. Methods The authors used an adaptation from the Social Readjustment Rating Scale (SRRS) to describe the prevalence of life events; they developed a 4-factor stressful life events subscales and used Medical Outcomes Social Support Scale, ...
Few studies on resilience in young children model risk appropriately and test theory-led hypotheses about its moderation. This study addressed both issues. Our hypothesis was that for preschool childrens emotional/ behavioral adjustment in the face of contextual risk protective factors should be lo... mehr Few studies on resilience in young children model risk appropriately and test theory-led hypotheses about its moderation. This study addressed both issues. Our hypothesis was that for preschool childrens emotional/ behavioral adjustment in the face of contextual risk protective factors should be located in the cognitive domain. Data were from the first two sweeps of the UKs Millennium Cohort Study. The final study sample was 4,748 three-year-old children clustered in 1,549 Lower layer Super Output Areas in nine strata. Contextual risk was measured at both area (with the Index of Multiple Deprivation) and family (with proximal and distal adverse life events experienced) level. Moderator ...
Previous studies have demonstrated an association between negative life events (NLEs) in childhood and resilience/posttraumatic growth (PTG) with regard to the pathogenesis of major depressive disorder. We hypothesized that the type and timing of NLEs interact to influence mental health in the general youth population. Therefore, the present study aimed to examine the effects of NLE timing and intensity on current depressive symptoms, and to determine the direct and indirect effects of NLEs/resilience on PTG and depression among non-clinical adolescents. Data were collected from 1,038 high school students across seven high schools in Fukui, Japan, during their freshman and sophomore years (648 boys and 390 girls, mean age = 15.71, SD = 0.524). Respondents completed a set of questionnaires designed to evaluate the type and timing of NLEs, depressive and traumatic symptoms, and PTG. Cluster analysis was used to divide participants into three groups based on outcomes:
At some point in their lives, everyone will experience a stressful life event. Usually, someone can cope with and make meaning from the event. However, the body of research investigating the impact of severe and/or chronic exposure to stressful life events on the brain shows that harmful effects of stress exposure accumulate. Considering the extant literature regarding religious meaning making in light of these findings and the robust literature on spiritual transformation following stressful life events, I developed three hypotheses: 1) stressful life events increase risk of (non)religious ID change, 2) earlier events continued to impact later ID changes, and 3) risk of ID change was similar across change groups. This study analyzed a nationally representative longitudinal dataset of US children born between 1980 and 1984 (N = 8984). The final analyses used multiple imputation to account for missing data and did not find evidence supporting the hypotheses ...
Mary Gilliam, Erika E. Forbes, Peter J. Gianaros, Kirk I. Erickson, Lauretta M. Brennan, Daniel S. Shaw, Maternal depression in childhood and aggression in young adulthood: evidence for mediation by offspring amygdala-hippocampal volume ratio, Journal of Child Psychology and Psychiatry, 2015, 56, 10, ...
The binding protein FKBP5 is an important modulator of the function of the glucocorticoid receptor, the main receptor of the stress hormone system. This turns the FKBP5 gene into a key candidate for gene-environment interactions, which are considered critical for pathogenesis of stress-related disorders. The authors explored gene-environment interactions between FKBP5 gene variants and adverse life events in predicting the first occurrence of a major depressive episode.The analyses were based on 884 Caucasians in a 10-year prospective community study. At baseline, they were 14-24 years old and did not fulfill criteria for a major depressive episode. The DSM-IV-based Munich Composite International Diagnostic Interview was used to assess adverse life events preceding baseline and major depressive episodes during follow-up. On the basis of previous findings, five single-nucleotide polymorphisms (SNPs) within the FKBP5 gene were selected for genotyping.While the authors did not observe genetic main ...
BACKGROUND: It is well-documented that African Americans have elevated risk for cognitive impairment and dementia in late life, but reasons for the racial disparities remain unknown. Stress processes have been linked to premature age-related morbidity, including Alzheimers and related dementias (ADRD), and plausibly contribute to social disparities in cognitive aging. OBJECTIVE: We examined the relationship between stressful life events and cognitive decline among African American and White participants enrolled in the Wisconsin Registry for Alzheimers Prevention (WRAP). METHODS: Linear mixed models including demographic, literacy, and health-related covariates were used to estimate (1) relationships between a life event index score and decline in cognitive test performance in two domains of executive function (Speed & Flexibility, Working Memory) and one domain of episodic memory (Verbal Learning & Memory) among 1,241 WRAP enrollees, stratified by race, and (2) contributions of stressful life ...
The key finding in the present study is that individuals who reported extremely stressful life events within finance- and work-related life domains had significantly higher odds for having the metabolic syndrome. The risk was further increased according to accumulation of stressful finance-related events and according to having at least three events in any of the life domains we measured, namely finance, work, social relationships, health, and housing. Accumulation of stressful finance- and work-related life events and having at least three stressful events in any of the life domains also associated significantly with insulin resistance, obesity, and triglycerides. The associations were not confounded by sex, age, lifestyle, or family history of diabetes.. Our findings are in agreement with previous studies (9-13) by showing that major stress-related events associate with an increased risk of having the metabolic syndrome. However, our findings further suggest that of the life events we ...
A recent study into the role social circumstances and life events have on mental health found the biggest determinant of chronic anxiety and depression is
The Holmes And Rahe Stress Scale is often used by doctors to find this answer: Can the most stressful life events predict future illness?
The Holmes And Rahe Stress Scale is often used by doctors to find this answer: Can the most stressful life events predict future illness?
Okay, guys. Buckle up! This is going to be a wordy post, but I promise it will be an extremely rewarding read. Last week was National Library Week. Libraries across the country celebrated in various ways, but we all shared the same theme: Lives Change @ Your Library. Here at EPL we talked to you. My colleagues and I, armed with cookies and a laptop, asked you to share your library stories. We asked you to tell us what you love about the library and how it may have impacted your life. I have to say that the experience was both entertaining and very humbling. The shorter stories I tweeted; the longer ones I will share with you here. Know that every single one of you warmed my heart and made me thankful that Im able to work with people like you.
© 2015 Elsevier Ltd All rights reserved. Adversity, particularly in early life, can cause illness. Clues to the responsible mechanisms may lie with the discovery of molecular signatures of stress, some of which include alterations to an individuals somatic genome. Here, using genome sequences from 11,670 women, we observed a highly significant association between a stress-related disease, major depression, and the amount of mtDNA (p = 9.00 × 10 | sup | -42 | /sup | , odds ratio 1.33 [95% confidence interval [CI] = 1.29-1.37] ) and telomere length (p = 2.84 × 10 | sup | -14 | /sup | , odds ratio 0.85 [95% CI = 0.81-0.89]). While both telomere length and mtDNA amount were associated with adverse life events, conditional regression analyses showed the molecular changes were contingent on the depressed state. We tested this hypothesis with experiments in mice, demonstrating that stress causes both molecular changes, which are partly reversible and can be elicited by the administration of corticosterone.
In most cultures, alcohol is the most frequently used brain depressant and a cause of considerable morbidity and mortality. At some time in their lives, as many as 90% of adults in the United States have had some experience with alcohol, and a substantial number (60% of males and 30% of females) have had one or more alcohol-related adverse life events (e.g., driving after consuming too much alcohol, missing school or work due to a hangover). Fortunately, most individuals learn from these experiences and moderate their drinking, thus avoiding Alcohol Dependence or Abuse(APA 212).. As Im sure is the case with most everyone, I originally quit drinking more than a year before my 21st birthday, thus "avoiding alcohol dependence". Or so it seemed at the time. In hindsight, the behaviors that caused me to quit that first time were relatively benign. I had (and have) a long-standing problem with social anxiety and having a few drinks had an almost miraculous effect on my ability to interact with ...
Off to class, but not quite making it A stressful event has just occurred, and once the dust has settled and the adrenal rush quiets down, next comes the inevitable question. Will my lupus flare? Traumas, losses and major life events have an effect on everyone experiencing them, but the impact can be more intense…
Ive noticed and commented on it my whole life, yet it never ceases to amaze me how my real life experience changes my priorities.. Readers of this blog know all too well what I obsessively worried about when I first began treatment for cancer. The side effects from chemo were no joke - nausea (we have medication for that now), heart damage from the taxol (years from now) and lung damage from the radiation (small possibility, but by no means a certainty - Ill worry about it when and if the time comes). What I was obsessively concerned about - when will my hair start falling out? Every time I shampooed, I asked myself - Is today the day? Is today the day it comes out in clumps in my hands? Sometimes Id get out of the shower and just sob - my loss of hair wasnt total, but my already fine hair was becoming increasingly thin. I knew I should have it cut very short, but I dreaded going to the salon, leaning back into the shampoo sink, and worried that that would be the moment my hair as a unit ...
An average of 15 million adults each year experience the symptoms of major depression. The symptoms of this illness are severe, persistent and may lead to other serious complications. Major depression could result from a traumatic event or it may slowly develop over time due to a variety of previous and current traumatic life events. Major depression can lead to serious complications such as substance abuse and/or suicide.
Health, ...FRIDAY March 29 (HealthDay News) -- Stressful life events increase wo...Stillbirth is the death of the fetus at 20 or more weeks of pregnancy....The study included more than 2000 women who were asked if they experi...At least one stressful life event was reported by 83 percent of women ...,Pregnant,Women,Under,Stress,May,Be,at,Higher,Risk,for,Stillbirth,medicine,medical news today,latest medical news,medical newsletters,current medical news,latest medicine news
A lot of people are often asking others, hey can you Change my life? So, do you believe someone can change your life? Check out here and youll know
Americans are moving from job to job -- and career to career -- as never before. And its not just about money: Many are choosing new jobs that might give them a better life. In a series of reports for Morning Edition, NPRs Ketzel Levine talks with those taking the leap.
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I do so love the desserts, but perhaps I should be working out more. Sobering fact: I weighed more three years ago than I do now. So, since I cant gain weight the developed-world way through eating I figure I must starting exercising and get a little muscle mass. Someone told me the other day they appreciated the indent of my chest as a place to rest their head. As glad as I am that they like this feature, having a chest that can double as a cereal bowl is not really to my liking. Pecs! Abs! Gluts! Biceps! Triceps! Quadceps! Any kind of cep! Ill exercise them all ...
its been a while since Ive written here. Weve had several major life events that are difficult to speak about. When Ive been overwhelmed recently, Ive gone outside into the woods looking for what is permanent. The seasons come and go, but they always come around again. The leaves come down, but they come…
Purpose: This preliminary study investigated the relationship between worry and smoking to cope among socially anxious smokers. Pathological worry is defined as excessive and unrealistic apprehension characterized by uncontrollable thoughts which focus on negative outcomes (Borkovec, Shadick, & Hopkins, 1991; Andrews et al., 2010). Worry is based in non-reality, but comprises a component of perceived control, such that individuals who worry use it to help them find solutions and prevent bad things from happening. Therefore, individuals may cling to worry in order to increase personal control and help them manage uncertainty during negative life events (Anderson & Schwartz, 1992; Freeston et al., 1994). Research indicates that among anxious individuals who smoke, worry is correlated with positive beliefs about smoking, such as "worry will help me cope," and "if I worry I will solve the problem," leading to a perception that negative affect can be personally controlled (Andrews et al., 2010; ...
Its long been known that chronic stress, defined as a prolonged physical, mental, or emotional factor that results bodily or psychological tension, can alter the normal trajectories of childhood brain development (See "Early Life Experience, Critical Periods, and Brain Development"), leading to increased risk for neuropsychiatric disorders. What hasnt been known are the various mechanisms by which stress can make those changes, negative or positive, to the brain. Bruce McEwen, a pioneering neuroscientist who has spent his career studying the effects of stress, as well as a member of the Dana Alliance for Brain Initiatives (DABI), said that stress is one of the most commonly used words in the English language, yet it means something different to each person. Thats because the effects of stress are dependent on both genetics and environment.. "There used to be a time when we argued about what was more important to development-genes or environment. But now we understand there is an almost ...
Early life experiences exert a profound and long-lasting influence on physical and mental health throughout life. The efforts to identify the primary causes of this have significantly benefited from studies of the epigenome-a dynamic layer of inf...
By Kym R. Ahrens, Renee Spencer, Mavis Bonnar, Alexis Coatney and Tyson Hall; Abstract: To explore how attitudes, norms, behaviors, responses to early life experiences, and protective factors influence
I was speaking with a friend a few weeks ago who recently lost her father very suddenly. I felt awful for her and cannot imagine what she is going through with that loss as Im sure she cannot imagine what Im going through. We talked about our crappy situations and agreed that if one thing was for sure, we both didnt feel safe anymore. We had both lead pretty great lives, with no major crisis, and all of a sudden...BAM...life changes just like that. Prior to my sickness I didnt think that I took life for granted, I had watched enough news programs and read enough magazine stories to know that bad things happen to good people. But when it happens to you, all bets are off. You just feel like for the rest of your life you know something horrible could happen to you, your family or your friends. And thats an awful feeling. I just dont have that same level of "safeness" that I used to have before when the worst thing that happened to me was that my boyfriend moved to Pittsburgh. My faith has ...
Before 2000) Abstract A value-laden basis for commitment to goals and the behavioral and affective sequelae of commitment were examined in the context of a stressful life event. Fifty-seven women who were ... Created on 15 May 2013 ...
H, Marian and Chris! Good to see hear from you. There was no change in my hair, only that it was all gray when it came in and I looked like my Dad!!!As far as life changes, there have been many for me as well, Chris, and there are times when I feel numb. I think it is hard to celebrate being a survivor, of course we are happy, but sad for those who are not. And sometimes it all seems like one big crap shoot ...
Though its never easy or the way you thought things would go, it seems inevitable that in the course of a life, friendships come and go. Some are situational, like a classmate who you lose touch with after the semester ends. Some are just the victims of a Life Change that leaves your interests so disparate that you just drift away because now, when you talk, you struggle a little too hard to find stuff to talk about. They all suck, but theyre a part of life. Theres also those blowout endings, where one party does something the other cannot forgive. Ive lost a few friends to these over the years, some spectacular ones in the last couple and though the events themselves sucked (again, some WAY worse than others) I get it. Even if we tried to bridge that new-found difference afterwards, in the end we both saw something in each other that made it painfully clear that being in touch was no longer going to work. Sad, yes, but at least we can all pinpoint the moment when it ended and we all are on ...
Looking for information on the manga Zetman? Find out more with MyAnimeList, the worlds most active online anime and manga community and database. Jin is a strange kid with an angel mark on his hand. He lives a poor but peaceful life with his grandfather, along with the other destitute and abandoned vagabonds near the river. One day, his peaceful life changes when a strange monster named player appears, chopping off heads and killing everyone who appears in front of it.
Caregiving often starts small before morphing into a full-time job. Sometimes it results from a sudden life change. Here are the tools you need for success.
Aging comes with some important and troubling life changes. Coping with these changes isnt easy and may increase the risk for addiction in aging women.
As we move into higher vibrations or love energy, everyday we have the opportunity to reinvent ourselves in some new way. We know if we keep doing the same old thing, nothing in our lives changes and we feel stuck and frustrated. But if we have the courage and spirit to try something new by…
Speaking for myself only, I have figured out how to reconcile the "wins" people claim in auditing versus my skepticism in the general effectiveness of auditing as a therapeutic technique. After talking to a few exs who had claimed significant wins in auditing and trying to look at alternative explanations that may have contributed to their positive life changes, I was able to agree that they in fact had gotten significant value out of auditing. However, I have enough experience in looking at drug trials and in other sorts of population analysis. Lets consider a rigorously controlled trial of auditing versus a placebo form of auditing, perhaps where the dial on the e-meter is set randomly based on some external factor unknown to the auditor, or there is some other mechanism for divorcing the e-meters feedback from what the device would indicate in the test group. I strongly suspect that a rigorous clinical trial would reveal that auditing is relatively close to a placebo in its effectiveness. ...
Big Idea: Life changes. People change. Ideals change as society grows and matures. What was good for mankind years ago may not continue to be good for people of today. To ensure we protect our freedoms we need to evaluate what ideals we still believe in ...
A seventeen-year-old aspiring reporter decides to write a scathing exposé on an elite Washington, D.C., private school, but her life changes when her subject comes to her for help ...
Heres a list of 25 positive life changes you can make, no matter how many candles are on your cake. Consider it a #goals list for the ages.
Why does it matter where you get the Suboxone? Well, when you buy street Suboxone you still associate with dealers, you rarely get counseling, youre not forced to make life changes and you use it more like drug than a medication to get clean.
In todays gossip roundup: The Kardashian-Jenners are making big life changes, Susan Sarandon is a stoner, and its Taylor Swifts birthday.
Weve always had rules in our household about technology use. Bedrooms are technology free zones. No checking email from bed, no watching TV when you go to sleep. The table is the same way. Meals are unfettered by technology, please and thank you. But the truth is, we have a problem. More specifically, I have a problem.. The problem is that the lure of connectedness is following me wherever I go, and not allowing technology at the dinner table isnt helping the situation. Not anymore.. The problem, of course, is dopamine. A recent Life Hacker article on why technology is so addictive explains, "We can develop a dopamine release from many kinds of addictive behavior. Checking email is one in particular. You may not like spending long amounts of time in your inbox, but you probably think about checking it pretty often. When you hear that ding (or vibrate), you know theres something waiting for you." An article from The New York Times series Your Brain on Computers explained it this way: "The ...
2 months is so recent, give yourself a break. You can take as long as it takes to process anything youre going through, dont be worried about what other people think. Im sure most people will understand, & if they dont you dont really want them in your life anyway. It could be 4 years down the line, & you would still have every right to be healing from what youve been through. Theres no time limit to getting better, I dont know why it seems to be such a societal pressure to put back on that brave face like everything is great. It will be better eventually, but you dont have to deny your emotions & what youre going through. Go easy on yourself. Keep doing what youve got to do to get through, eventually youll be able to focus better, youre still processing what youve been through. Im so sorry for your loss, I wish you all the best & know that youre gonna be alright. Youre not alone ...
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Quality and Patient Safety Implementation Assistant There are very few people who get to see the inside of a hospital morgue. This may not be everyones cup of tea, but for me it was a golden opportunity. Read to find out how my curiosity led me to places I hadnt imagined and taught me the importance of embracing the unexpected.. ...