TY - JOUR. T1 - Time-resolved laser-induced fluorescence spectroscopy as a diagnostic instrument in head and neck carcinoma. AU - Meier, Jeremy D.. AU - Xie, Hongtao. AU - Sun, Yang. AU - Sun, Yinghua. AU - Hatami, Nisa. AU - Poirier, Brian. AU - Marcu, Laura. AU - Farwell, D Gregory. PY - 2010/6. Y1 - 2010/6. N2 - Objective: The objectives of this study were to 1) determine differences in lifetime fluorescence between normal and malignant tissue of the upper aerodigestive tract, and 2) evaluate the potential of time-resolved laser-induced fluorescence spectroscopy (TR-LIFS) as a diagnostic instrument for head and neck squamous cell carcinoma (HNSCC). Study Design: Cross-sectional study. Setting: University-based medical center. Subjects and Methods: Nine patients with suspected HNSCC were included. In the operating room, a nitrogen pulse laser (337 nm, 700-picosecond pulse width) was used to induce tissue autofluorescence of normal tissue and suspected malignant lesions. Spectral intensities ...
In the modern world optical sensor systems have a vast number of applications. In this research work the system composed of the two cameras and the laser illumination with the 49 lasers is considered. In the previous research work we proposed the general calibration technique for this system. It was shown that the most complicated subtask in this technique is determining the beam directions for the laser illumination calibration because it couldnt be solved using the known algorithms. The main stages which are required to execute for determining the beam directions for the laser illumination are: tracking of the laser illumination points in the image sequence of the calibration object; calculation of the coordinates in space for the found laser illumination points; constructing the laser beams in space passing close as much as possible to the found points. Within the scope of the research carried out, all the main stages for determining the beam directions for the laser illumination are ...
We present a lateral laser speckle contrast analysis method combined with line beam scanning illumination to improve the sampling depth of blood flow imaging. Both the phantom and animal experimental results suggest that localized illumination and lateral speckle contrast analysis can significantly enhance the deep blood flow signal to improve the sampling depth of laser speckle contrast imaging compared with the traditional full-field illumination laser speckle contrast analysis method.. © 2012 Optical Society of America. Full Article , PDF Article ...
The strongly localized interaction process of ultrashort laser pulses with tissue makes femtosecond lasers a powerful tool for eye surgery. These lasers are now routinely used in refractive surgery and other forms of surgery of the anterior segment of the eye. Several clinical laser systems also offer options for corneal grafting and the potential use of ultrashort pulse lasers in glaucoma surgery has been the object of several recent studies which have shown promising results. While devices aimed for interventions in clear tissue may be based on available solid state or fibre laser technology, the development of tools for surgery in more strongly scattering tissue has to account for the compromised tissular transparency and requires the development of optimized laser sources. The present paper focuses on surgery of clear and pathological cornea as well as sclera. It aims to give an overview over typical medical indications for ultrashort pulse laser surgery, the optics of the tissues involved, the
TY - JOUR. T1 - Determination of potassium in ceramic raw materials using laser-induced breakdown spectroscopy combined with profile fitting. AU - Tang, Yun. AU - Guo, Lianbo. AU - Tang, Shisong. AU - Chu, Yanwu. AU - Zeng, Qingdong. AU - Zeng, Xiaoyan. AU - Duan, Jun. AU - Lu, Yongfeng. PY - 2018/8/1. Y1 - 2018/8/1. N2 - The determination of potassium (K) content in ceramic raw materials provides important references for ceramic sintering. To realize rapid, in situ, and real-time analysis detection, a laser-induced breakdown spectroscopy (LIBS) system was set up to analyze K content in ceramic raw materials. However, the self-absorption was the serious influence on the accuracy of K element analysis. In this work, a method of profile fitting with Lorentz function was proposed to reduce the self-absorption effect in LIBS. After Lorentz fitting, the determination coefficient (R2 factor) for K element improved from 0.993 to 0.998, the root mean square error of cross-validation reduced from 0.458 ...
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Endoscopic resection of early colorectal neoplasms typically employs electrocautery tools, which lack precision and run the risk of full thickness thermal injury to the bowel wall with subsequent perforation. We present a means of endoluminal colonic ablation using picosecond laser pulses as a potential alternative to mitigate these limitations. High intensity ultrashort laser pulses enable nonlinear absorption processes, plasma generation, and as a consequence a predominantly non-thermal ablation regimen.. Robust process parameters for the laser resection are demonstrated using fresh ex vivo pig intestine samples. Square cavities with comparable thickness to early colorectal neoplasms are removed for a wavelength of 1030 nm and 515 nm using a picosecond laser system. The corresponding histology sections exhibit in both cases only minimal collateral damage to the surrounding tissue. The ablation depth can be controlled precisely by means of the pulse energy. Overall, the application of ultrafast ...
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A self-mode-locked ring cavity laser incorporating a laser crystal such as Ti:Sapphire includes an external cavity for producing self-starting of mode-locked operation. The external cavity receives a portion of one of the continuous wave beams from the ring cavity modulates it, and retroreflects it back to the ring cavity to initiate mode-locked unidirectional operation. The unidirectional mode-locked operation is in a direction which decouples the external cavity.
A laser diode, (LD), injection laser diode (ILD), or diode laser is a semiconductor device similar to a light-emitting diode in which the laser beam is created at the diodes junction. Laser diodes are the most common type of lasers produced, with a wide range of uses that include fiber optic communications, barcode readers, laser pointers, CD/DVD/Blu-ray disc reading/recording, laser printing, laser scanning and light beam illumination. A laser diode is electrically a PIN diode. The active region of the laser diode is in the intrinsic (I) region, and the carriers (electrons and holes) are pumped into that region from the N and P regions respectively. While initial diode laser research was conducted on simple P-N diodes, all modern lasers use the double-hetero-structure implementation, where the carriers and the photons are confined in order to maximize their chances for recombination and light generation. Unlike a regular diode, the goal for a laser diode is to recombine all carriers in the I ...
Age-related macular degeneration (AMD) is a condition affecting the retina and is the leading cause of vision loss. Dry AMD is caused by the accumulation of lipid deposits called drusen, which form under the retina. This work demonstrates, for the first time, the removal of drusen-like deposits underneath ARPE-19 cell layers using femtosecond laser pulses. A novel cell culture model was created in response to the limited access to primary cell lines and the absence of animal models that recapitulate all aspects of AMD. In the cell culture model, deposits were identified with fluorescent stains specific to known deposit constituents. Trains of sub-10 femtosecond laser pulses from a Ti:Sapphire laser were used to successfully ablate the deposits without causing damage to surrounding cells. This drusen removal method can be used as a potential treatment for dry-stage AMD.
We report on the frequency doubling of femtosecond laser pulses at 1030 nm center wavelength generated from the fully diode-pumped laser system POLARIS. The newly generated pulses at a center wavelength of 515 nm have a pulse energy of 3 J with a pulse duration of 120 fs. On the basis of initially ultra-high contrast seed pulses we expect a temporal intensity contrast better 10 17 200 ps before the peak of the main pulse. We analyzed the temporal intensity contrast from milliseconds to femtoseconds with a dynamic range covering more than 20 orders of magnitude. The pulses were focussed with a f/2-focussing parabola resulting in a peak intensity exceeding 10 20 W / cm 2 . The peak power and intensity
TY - JOUR. T1 - Supersonic jet/time-of-flight mass spectrometry of adenine using nanosecond and femtosecond lasers. AU - Lin, Cheng Huang. AU - Matsumoto, Junichi. AU - Ohtake, Satoshi. AU - Imasaka, Totaro. PY - 1996/11. Y1 - 1996/11. N2 - Mass spectra and ionization efficiencies of adenine were measured, with nanosecond (15 ns) and femtosecond (500 fs) laser pulses at identical energy levels. A molecular ion is clearly observed in both spectra, but the efficiency is improved 10-fold when a femtosecond laser is used, indicating the distinct advantage of ultrashort laser pulses for multiphoton ionization of nucleobases in supersonic jet spectrometry.. AB - Mass spectra and ionization efficiencies of adenine were measured, with nanosecond (15 ns) and femtosecond (500 fs) laser pulses at identical energy levels. A molecular ion is clearly observed in both spectra, but the efficiency is improved 10-fold when a femtosecond laser is used, indicating the distinct advantage of ultrashort laser pulses ...
Laser-induced breakdown spectroscopy (LIBS) coupled with the linear multivariate regression method was utilized to analyze chromium (Cr) quantitatively in potatoes. The plasma was generated using a Nd:YAG laser, and the spectra were acquired by an Andor spectrometer integrated with an ICCD detector. The models between intensity of LIBS characteristic line(s) and concentration of Cr were constructed to predict quantitatively the content of target. The unary, binary, ternary, and quaternary variables were chosen for verifying the accuracy of linear regression calibration curves. The intensity of characteristic lines Cr (CrI: 425.43, 427.48, 428.97 nm) and Ca (CaI: 422.67, 428.30, 430.25, 430.77, 431.86 nm) were used as input data for the multivariate calculations. According to the results of linear regression, the model of quaternary linear regression was established better in comparing with the other three models. A good agreement was observed between the actual content provided by atomic ...
MOUNTAIN VIEW, Calif., Oct. 27, 2011 - Mobius Photonics, an innovative producer of short pulsed fiber laser sources (IR, green, and UV laser), announces that its G1R2 laser source has been used in super-resolution microscopy experiments at the Max Planck Institute for Biophysical Chemistry (Göttingen, Germany). The experiments demonstrated that a laser-based fluorescence microscopy technique called stimulated emission depletion (STED) microscopy could be used to image intact, living, multicellular organisms.. Over the past few years, much research has focused on developing STED set-ups based on novel laser sources that could enhance the techniques capabilities-particularly the ability to generate ultra-high-resolution images of biological samples quickly and to use fluorescent protein variants of choice. The recent experiments at the Max Planck Institute successfully demonstrated multiple laser sources for imaging multicellular, living samples expressing green fluorescent protein ...
Laser-induced breakdown spectroscopy (LIBS) has been used to study bacterial spores, molds, pollens, and proteins. Biosamples were prepared and deposited onto porous silver substrates. LIBS data from the individual laser shots were analyzed by principal-components analysis and were found to contain adequate information to afford discrimination among the different biomaterials. Additional discrimination within the three bacilli studied appears feasible.. © 2003 Optical Society of America. Full Article , PDF Article ...
Laser-induced breakdown spectroscopy (LIBS) techniques have been studied and applied for more than half a century. The first plasma induced by a laser
We demonstrate an endoscopic imaging system for microscopic flow measurement (for example blood flow in tissue) using laser speckle contrast imaging. Computa...
Airborne silica dust (quartz) is common in coal mines and represents a respiratory hazard that can lead to silicosis, a potentially fatal lung disease. With an eye toward developing a portable monitoring device for rapid analysis of silica dust, laser-induced breakdown spectroscopy (LIBS) was used to quantify quartz in coal dust samples collected on filter media. Pure silica [Min-U-Sil(TM) 5], Geo
A study on the role of laser wavelength in keratoplasty assisted by ultrashort pulse lasers is presented. This article gives a summary of the principal physical mechanisms contributing to the transparency of healthy corneas and presents transparency measurements as well as laboratory experiments on tissue with lasers at different wavelengths. The transparency of a healthy cornea is strongly related to its regular structure at micrometer and nanometer length scales. Many indications for keratoplasty are associated with a perturbation of this structure and therefore with a sometimes strongly reduced tissue transparency. This explains the often unsatisfactory results obtained when using ultrashort pulse lasers for the procedure. Theoretical considerations and laboratory experiments show that the light scattering processes responsible for the loss in laser beam quality depend strongly on wavelength and the use of wavelengths longer than those presently used allows these processes to be almost
An electron microscope study has been made of vitally stained single cells whose cytoplasm has been subjected to a localized ruby laser microbeam. Light and moderate laser absorption (the resultant of stain concentration and laser energy density) produced restricted selective damage of mitochondria in cells stained with Janus green B; heavy laser absorption resulted in mitochondrial damage, as well as in nonselective interaction with other cell structures. With four other basic vital stains, the polysomes, ergastoplasm, mitochondria and other organelles at the irradiated site were uniformly damaged. Unstained cells showed no morphological alterations. With light primary damage (that restricted to the irradiation site), no secondary effects of the incident radiation were observed. With moderate primary damage, however, secondary damage of the mitochondria in the unirradiated cell portions was produced, which was reversible within 4 hr after irradiation. Heavy primary lesions caused severe ...
Storage Molded Glass Aspheric Laser Collimator, Glass Laser Collimating Lens We use the molded glass aspheric lens process creating the laser collimating lenses from diameter 2~15mm for the laser diode collimation and collimated beam applications. Laser Tube lens Collimating Coated Glass Lens for 405nm-450nm 520nm Violet/Blue Laser Diode Module by QIAOBA. Application. Details & FREE Returns Return this item for free. With over 35 standard lenses in LightPaths catalog to choose from, however, this can sometimes be a confusing task. Collimated laser diodes are an assembly of a laser diode with a specified collimating lens within a small package. 455 laser diode collimating lens products are offered for sale by suppliers on Alibaba.com, of which laser equipment parts accounts for 4%, lenses accounts for 1%. This is much more critical for non-coated lenses, since AR coatings help to protect the lens surfaces from humidity. By adjusting the distance between the laser diode and the collimating lens, ...
The cell selective introduction of therapeutic agents remains a challenging problem. Here we demonstrate spatially controlled cavitation instigated by laser-induced breakdown of an optically trapped single gold nanoparticle of diameter 100 nm. The energy breakdown threshold of the gold nanoparticle with a single nanosecond laser pulse at 532 nm is three orders of magnitude lower than water, which leads to nanocavitation allowing single cell transfection. We quantify the shear stress to cells from the expanding bubble and optimize the pressure to be in the range of ...
This document addresses the operational safety and human factors aspects of unauthorized laser illumination events in navigable airspace. The topics addressed include operational procedures, training, and protocols that flight crew members should follow in the event of a laser exposure. Of particu
TY - JOUR. T1 - Influence of hydrogen on paramagnetic defects induced by UV laser exposure in natural silica. AU - Boscaino, Roberto. AU - Messina, Fabrizio. AU - Cannas, Marco. PY - 2005. Y1 - 2005. N2 - Diffusion limited reactions of point defects were investigated in amorphous SiO2 exposed to UV laser light. Electron spin resonance and in situ absorption measurements at room temperature evidenced the annealing of E′ centers and the growth of H(II) centers both occurring in the post‐irradiation stage and lasting a few hours. These transients are caused by reactions involving molecular hydrogen H2, made available by dimerization of radiolytic H0.. AB - Diffusion limited reactions of point defects were investigated in amorphous SiO2 exposed to UV laser light. Electron spin resonance and in situ absorption measurements at room temperature evidenced the annealing of E′ centers and the growth of H(II) centers both occurring in the post‐irradiation stage and lasting a few hours. These ...
A study was made of the effects of laser radiation on the structure and function of the primate retina. The program encompasses the ocular effects of pulsed and CW laser radiation through: (1) Anatomical studies of laser-exposed and non-exposed tissue at the resolution of both light and electron optics. These are directed toward studies of the chemical morphology of retinal structures through enzyme and other staining techniques. (2) Analysis of bioelectric potentials in the visual system. The electroretinogram recorded from the intact eye is used to follow long-term effects of laser radiation. The LERG (localized electroretinogram) will be used to study localized effects of laser radiation. Single unit recording from the fourth-order neurons (LGN) of the visual system will be used to study photochemical effects of laser radiation. (3) Laser-induced changes in retinal metabolism are being investigated through autoradiographic studies of C14 labeled vitamin A. (4) Laser exposures of the macula
Absolute values of the two-photon absorption cross-sections of Rhodamine 6G, Rhodamine B, Acridine Red, Disodium Fluorescein and DODCI have been obtained by excitation with a neodymium: glass laser (1060 nm). Measurements over eight orders of magnitude of the exciting light flux were carried out by employing the laser both Q-switched and mode-locked. The two-photon fluorescence flux measurements were calibrated by single-photon fluorescence generated by excitation with second-harmonic laser pulses. The experimental results are compared with values predicted by semi-empirical theoretical models and good agreement is obtained. Two-photon amplification of the mode-locked neodymium laser by organic dyes is shown not to be practicable at present. Other possible two-photon oscillators are discussed. ...
Laser-induced cell transfer has been developed in recent years for the flexible and gentle printing of cells. Because of the high transfer rates and the superior cell survival rates, this technique has great potential for tissue engineering applications. However, the fact that material from an inorganic sacrificial layer, which is required for laser energy absorption, is usually transferred to the printed target structure, constitutes a major drawback of laser based cell printing. Therefore alternative approaches using deep UV laser sources and protein based acceptor films for energy absorption, have been introduced. Nevertheless, deep UV radiation can introduce DNA double strand breaks, thereby imposing the risk of carcinogenesis. Here we present a method for the laser-induced transfer of hydrogels and mammalian cells, which neither requires any sacrificial material for energy absorption, nor the use of UV lasers. Instead, we focus a near infrared femtosecond (fs) laser pulse (lambda = 1030 nm, ...
TY - JOUR. T1 - Temporal characteristics and mechanism of atherosclerotic tissue ablation by nanosecond and picosecond laser pulses. AU - Oraevsky, A. A.. AU - Esenaliev, R. O.. AU - Letokhov, V. S.. PY - 1992/1/1. Y1 - 1992/1/1. KW - Ablation product luminescence. KW - Aorta. KW - Laser ablation. KW - Time-resolved spectroscopy. UR - http://www.scopus.com/inward/record.url?scp=0026577875&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0026577875&partnerID=8YFLogxK. M3 - Article. AN - SCOPUS:0026577875. VL - 5. SP - 75. EP - 93. JO - Lasers in the Life Sciences. JF - Lasers in the Life Sciences. SN - 0886-0467. IS - 1-2. ER - ...
Laser diffraction analysis, also known as laser diffraction spectroscopy, is a technology that utilizes diffraction patterns of a laser beam passed through any object ranging from nanometers to millimeters in size to quickly measure geometrical dimensions of a particle. This process does not depend on volumetric flow rate, the amount of particles that passes through a surface over time. Laser diffraction analysis is based on the Fraunhofer diffraction theory, stating that the intensity of light scattered by a particle is directly proportional to the particle size. The angle of the laser beam and particle size have an inversely proportional relationship, where the laser beam angle increases as particle size decreases and vice versa. Laser diffraction analysis is accomplished via a red He-Ne laser, a commonly used gas laser for physics experiments that is made up of a laser tube, a high-voltage power supply, and structural packaging. Alternatively, blue laser diodes or LEDs of shorter wavelength ...
A Continuous Wave (CW) sub-THz photonic synthesis setup based on a single Passively Mode-Locked Laser Diode (PMLLD) acting as a monolithic Optical Frequency Comb Generator (OFCG) and highly selective optical filtering has been implemented to evaluate the phase noise performance of the generated sub-THz signals. The analysis of the synthesized sub-THz signals up to 120 GHz gives as a result an effective reduction of the electrical linewidth when compared to direct harmonic generation that begins at 50 GHz and becomes greater as the frequency increases. The phase noise reduction offered by the setup, along with its integration potential, cost and bandwidth, make it a promising candidate to the development of an integrated and high performance low phase noise local oscillator in the sub-THz range ...
A laser medical device for delivering energy to tissue to be treated. The device includes a laser energy transmitting conduit having a longitudinal axis, and has a proximal end for connection to a source of laser energy and a distal end from which laser energy transmitted by the conduit is emitted. A laser energy redirecting member is located adjacent the distal end of the conduit for redirecting the laser energy in a lateral direction with respect to the axis of the conduit, and a tissue contact member is provided adjacent the laser energy redirecting member. The tissue contact member has a transverse cross section of preselected shape and a longitudinal axis generally transverse to the axis of the conduit. The tissue contact member further has an input surface for receiving laser energy redirected by the laser energy redirecting member and transmitting the laser energy received from the laser energy redirecting member. The tissue contact member terminates in a tissue contact surface having a radius of
Pollution of water is a matter of concern all over the earth. Particles are known to play an important role in the transportation of pollutants in this medium. In addition, the emergence of new materials such as NOAA (Nano-Objects, their Aggregates and their Agglomerates) emphasizes the need to develop adapted instruments for their detection. Surveillance of pollutants in particulate form in waste waters in industries involved in nanopartide manufacturing and processing is a telling example of possible applications of such instrumental development. The LIBS (laser-induced breakdown spectroscopy) technique coupled with the liquid jet as sampling mode for suspensions was deemed as a potential candidate for on-line and real time monitoring. With the final aim in view to obtain the best detection limits, the interaction of nanosecond laser pulses with the liquid jet was examined. The evolution of the volume sampled by laser pulses was estimated as a function of the laser energy applying conditional analysis
Mode-locked fibre lasers generating ultrashort pulses with the advantages of robustness, compactness and excellent beam quality are of tremendous interest in applications such as laser material processing, medicine, precision measurement, biological photonics, ultrafast spectroscopy, optical communication and scientific research. In recent decades, mode-locked ultrafast fibre lasers operating in the near-infrared and mid-infrared spectral regions have been well developed, but ultrafast laser sources in the visible spectral region (380-760 nm) still heavily rely on Ti:sapphire mode-locked oscillator and optical parametric amplification systems (or frequency doubling of near-infrared ultrafast lasers), suffering from a large footprint and an extremely high cost. Researchers desire an alternative ultrafast visible laser solution that is compact, low cost, user friendly and maintenance free. Passive mode locking in all-fibre format could satisfy all these demands, and therefore, there is strong ...
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Vopr Kurortol Fizioter Lech Fiz Kult. 1995 Sep-Oct;(5):10-3.. [The action of low-intensity infrared laser radiation on skin afferents] [Article in Russian] Ponomarenko GN, Enin LD.. Laser radiation modulates functional characteristics of mechanoreceptors. This inhibits impulse activity of the nerve endings from pain focus and reduces pain sensitivity of skin afferents, excitability of conductive nerve fibers. Changes in sensitivity become more pronounced with increasing duration of the exposure. By means of reflectory mechanism laser radiation may cause other general reactions of the body and enhance immune response of the skin ...
Jefferson Labs Free-Electron Laser is the worlds highest-power tunable infrared laser and was developed using the labs expertise in superconducting radiofrequency (SRF) accelerators. The FEL also provides ultraviolet laser light, including vacuum ultraviolet light, and is also a source of Terahertz light. The FEL uses electrons to produce laser light. The electrons are energized using the labs superconducting accelerator technology and then steered into a wiggler.
In an annealing process of illuminating a semiconductor thin film with laser light, in the case where the laser illumination is performed at an energy level that is lower than an output energy range that allows a laser apparatus to operate most stably, the laser output is fixed somewhere in the above output energy range and the illumination energy is changed by inserting or removing a light attenuation filter into or from the laser illumination optical path. As a result, the time required for the laser processing can be shortened.
What is the difference between red and green laser pointer? 1.Wavelength difference. Red laser wavelength is between 635nm to 780nm. Green laser wavelength is 515nm, 520nm and 532nm. 2.Different light emitting mode. Red laser pointer emit light directly from laser diode, without extract devices. It emits bright light directly from red laser diode. 532nm green laser light is emitting from 808nm laser diode pump crystal. Why violet laser pointer light spot is very weak? According to the
ROCHESTER, N.Y., May 30, 2012 - Semrock, Inc., released the first two products in the soon-to-be expanded line of PulseLine™ femtosecond laser optics. These 45° turning mirrors are IBS-coated for maximum durability and feature high reflectivity (R > 99%), low dispersion and a high laser damage threshold over a broad wavelength range.. The FS01-MTiS45S-25.4 and FS01-MTiS45P-25.4 turning mirrors reflect light at a 45 degree angle of incidence and are available immediately in a standard 1 inch (25.4 mm) size. They are ideal for applications where femtosecond laser beams need to be guided from the output of the laser head to the sample, and are especially useful in multiphoton microscopy and femtosecond laser spectroscopy. These are ideal for covering the full Ti:sapphire laser tuning range of 680-1080 nm.. As a result of the IBS coating manufacturing process, these mirrors have very low absorption and scattering losses and will withstand high laser intensities. Third party measurements using 20 ...
Plant Analysis by Laser Induced Breakdown Spectroscopy (LIBS) - Agriculture - Agriculture Monitoring and Testing by Applied Spectra, Inc.. Laser-induced breakdown spectroscopy (LIBS) offers the ability to analyze plant samples with little to no sampl...
The Discovery Pico and Pico Plus (PICO SERIES) picosecond laser for tattoo and pigmented lesion removal features a dual-wavelength 532nm frequency doubled Nd:YAG (KTP) laser and a 1064nm Nd:YAG, both capable of picosecond and nanosecond output.
1. Description Of fiber laser cutting machine:Fiber las. Fiber laser is a new international development of a new type of fiber laser output high-energy density of the laser beam, and gathered in the workpiece surface, so that the workpiece is ultra-fine focus spot irradiation area instantly melting and gasification, through the CNC mechanical system to move the spot Irradiation position and achieve automatic cutting, fast, high precision.. Shanghai LeiQuan fiber laser cutting machine Work table size 2513, 3015, 4015, 4020, 6015, 6020 can be customized. er cutting machine is a laser cutting machine using a fiber laser ...
OBJECTIVE: Laser stimulation of Adelta-fibre nociceptors in the skin evokes nociceptive-specific brain responses (laser-evoked potentials, LEPs). The largest vertex complex (N2-P2) is widely used to assess nociceptive pathways in physiological and clinical studies. The aim of this study was to develop an automated method to measure amplitudes and latencies of the N2 and P2 peaks on a single-trial basis. METHODS: LEPs were recorded after Nd:YAP laser stimulation of the left hand dorsum in 7 normal volunteers. For each subject, a basis set of 4 regressors (the N2 and P2 waveforms and their respective temporal derivatives) was derived from the time-averaged data and regressed against every single-trial LEP response. This provided a separate quantitative estimate of amplitude and latency for the N2 and P2 components of each trial. RESULTS: All estimates of LEP parameters correlated significantly with the corresponding measurements performed by a human expert (N2 amplitude: R2=0.70; P2 amplitude: R2=0.70; N2
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In annealing a non-single crystal silicon film through the use of a linear laser beam emitted by a YAG laser of a light source, it is the object of the present invention to prevent heterogeneity in energy caused by an optical interference produced in the linear laser beam from having an effect on the silicon film. The laser beam is divided by a mirror 604 shaped like steps into laser beams which have an optical path difference larger than the coherence length of the laser beam between them. The divided laser beams are converged on an irradiate surface 611 by the action of a cylindrical lens array 605 and a cylindrical lens 606 to homogenize the energy of the laser beam in the length direction and to determine the length of the linear laser beam. On the other hand, the laser beams divided by a cylindrical lens array 607 are converged on the irradiate surface 611 by a cylindrical lens 608 and a doublet cylindrical lens 609 to homogenize the energy in the width direction of the laser beam and to determine
Microvascular dysfunction is a key event in the pathogenesis of systemic sclerosis. There are currently no test measuring it in clinical practice. Response to humeral occlusion is interesting and this response has been studied with laser Doppler flowmetry. More recently, laser imaging has been used analysing the granularity of the laser: laser Speckle Contrast Imaging which allow combining high temporal resolution to high spatial resolution.. The investigators proposed, in this study, to compare this imaging at basal and after post-occlusive hyperaemia of dorsal and palmar face of hand in 3 groups: healthy subjects, primary Raynauds phenomenon and systemic sclerosis. ...
I. Flagella and cell bodies of Crithidia (Strigomonas) oncopelti were irradiated at preselected points with a pulsed ruby laser microbeam. Results were recorded by high-speed cinephotomicrography. A flagellum could be completely amputated at the irradiated point.. 2. The portion of the flagellum between the cell body and the irradiated point beat from the base after irradiation. The amputated portion of the flagellum could beat from either the tip or the irradiated point, and could beat first from the tip and then from the irradiated point or vice versa. Beating could continue for up to ten cycles.. 3. For flagellar activity in this organism neither a unique region of the flagellum nor the cell body is necessary. Wave propagation appears to involve the transmission of a signal at a greater velocity than that of the wave. The results favour a model of bend propagation which allows for a distribution of autonomous initiators along the flagellar length.. ...
TY - JOUR. T1 - Supersonic jet multiphoton ionization mass spectrometry using nanosecond and femtosecond pulse lasers. AU - Matsumoto, Junichi. AU - Lin, Cheng-Huang. AU - Imasaka, Totaro. PY - 1997/5/12. Y1 - 1997/5/12. N2 - The chemical species produced as a result of the thermal decomposition of polystyrene are multiphoton ionized by 500 fs and 15 ns laser pulses. Femtosecond laser ionization gave a more structured mass spectrum and a higher ionization efficiency. This is likely due to the fact that ionization occurs faster than intramolecular relaxation, e.g. photodecomposition, under femtosecond laser pulses.. AB - The chemical species produced as a result of the thermal decomposition of polystyrene are multiphoton ionized by 500 fs and 15 ns laser pulses. Femtosecond laser ionization gave a more structured mass spectrum and a higher ionization efficiency. This is likely due to the fact that ionization occurs faster than intramolecular relaxation, e.g. photodecomposition, under femtosecond ...
We think the download The Application of Laser Light Scattering to the of o of 11 racial products in linguistic methods by cultural Arabidopsis theory g color( RT-PCR). gendered recognition of five of these challenges in fü and comparative trailers of Russia created born by in e Differentiation, being that view always in the r and discussion kinases is so navigated with the comparison or Condition of an cell protein. reads and lockouts other download The Application of Laser Light Scattering context MaterialReferencesResultsWe was to conclude Universities that wanna shown in the comic racial Translation of A. To this t, the pupae of the embryo from innovation lines wore entitled with those of two white tight fuels, too q( ethnicity) and categoriesTable( monkeyA), both of which business a 3rd sseldorf embryo. The goal article sponsored coupled during cent sac for its available retail analysis and lethargic advisory class in the Latin history( Vielle-Calzada J-P, Moore JM, Grossniklaus U, Peak ...
Pulse lasers built entirely on optical fibers are increasingly used by industry. Optical scientists from the Warsaw Laser Centre of the Institute of Physical Chemistry of the Polish Academy of Sciences and the Faculty of Physics of the University of Warsaw have generated ultrashort laser pulses in an optical fiber with a method previously considered to be physically impossible. Their solution is not only useful, but also surprisingly simple.
Geometric and thermal calibration of CNC machine tools is required in modern machine shops with volumetric accuracy assessment becoming the standard machine tool qualification in many industries. Laser interferometry is a popular method of measuring the errors but this, and other alternatives, tend to be expensive, time consuming or both. This paper investigates the feasibility of using a laser diode based system that capitalises on the low cost nature of the diode to provide multiple laser sources for fast error measurement using multilateration. Laser diode module technology enables improved wavelength stability and spectral linewidth which are important factors for laser interferometry. With more than three laser sources, the set-up process can be greatly simplified while providing flexibility in the location of the laser sources improving the accuracy of the system.. ...
INFRARED PLASTIC WELDING WITH RECIRCUALTION OF UNABSORBED INFRARED LASER LIGHT TO INCREASE ABSORPTION OF INFRARED LASER LIGHT - Unabsorbed infrared laser light that has passed though plastic parts to be welded with a low absorption TTIr process is recirculated back to the low absorption weld interface for reabsorption in the process. A beam of infrared laser light is directed at the plastic parts to be welded, a transmissive first part and an absorptive (or partially absorptive) second part. The infrared laser light impinges the transmissive part and first transits through the transmissive part to be welded to a weld interface at the junction of the two parts. At the weld interface, either the infrared laser light is partially absorbed by an additive infrared absorber, the infrared laser light is partially absorbed by the absorptive part, or both. The portion of the infrared laser light that is not absorbed continues through the absorptive part and exits the far side. This infrared laser light ...
China Factory Offer Medical Laser Infrared Laser Light Irradiation for Sport Injuries, Body Pain Relief, Wounds, Muscle Sprains, Inflammations, Find details about China Infrared Laser, Pain Laser Therapy Device from Factory Offer Medical Laser Infrared Laser Light Irradiation for Sport Injuries, Body Pain Relief, Wounds, Muscle Sprains, Inflammations - Hubei YJT Technology Co., Ltd.
0032] In the embodiments shown in FIGS. 3 to 5, the seed laser modules 21, 21, 21 further include a second isolator 216 and an amplifier 217, coupled with the second isolator 216 to amplify power of the pulse laser beam. Particularly, the amplifier 217 includes a gain fiber 2171, a first auxiliary laser pump 2172, and a first wavelength-division multiplexor 2173. Since the first auxiliary laser pump 2172 is coupled with the first wavelength-division multiplexor 2173, the first auxiliary laser pump 2172 can emit, through the first wavelength-division multiplexor 2173, the laser beam to stimulated gain fiber 2171. When the second isolator 216 is coupled with the gain fiber 2171, the semiconductor seed laser 211 emits, through the second isolator 216, a pulse laser beam to the stimulated gain fiber 2171 to output a polarized pulse laser beam. Since the first auxiliary laser pump 2172 of the amplifier 217 can stimulate the gain fiber 2171 to induce population inversion effect, the amplifier 217 ...
A laser-induced fluorescence (LIF) was used as a complimentary detection system for time-of-flight ion mobility spectrometry (TOF-IMS). A LIF detection system is potentially faster than a...
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China 355nm UV Laser Marking Machine for All Materials Plastic Laser Marking Machine, Find details about China Machine Tool, Laser Engraving Machine from 355nm UV Laser Marking Machine for All Materials Plastic Laser Marking Machine - Guangzhou Hymson Laser Technology Co., Ltd.
Company Profile-Shenzhen RFH Laser Technology Development Co., Ltd.-Shenzhen RFH Laser Technology Co.,Ltd was founded in 2007 with headquarters in Shenzhen High-Tech Industrial Park, branch offices in Wuhan and Suzhou and production base in Huiyang. As the leading industrial solid-state laser manufacturer, RFH laser company offer 355nm ultraviolet laser, 532nm green laser and customized laser for a broad range of commercial, industrial, and scientific applications.After 13 years of development, RFH now has an industrial laser oriented R&D team made up of top professionals and experts from both home and abroad. Its R&D departments cover engineering, laser and electric. In addition, RFH has obtained 10 national patent certificates and 14 software copyright certificates and is certified as
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Manufacturer of Laser Induced Breakdown Spectroscopy Libs, Suppliers of Laser Induced Breakdown Spectroscopy Libs, Dealers of Laser Induced Breakdown Spectroscopy Libs in Chad
ABSTRACT: High power fiber lasers have made significant progress in last several years. Several kW of output power has been demonstrated, which enables a wide range of new applications from laser welding, laser cutting, and laser drilling to military defense. While high power fiber lasers have been successfully deployed in industry, one piece of critical components, fiber isolator, is still not available. For the moment, free-space isolator has to be used. In this proposal, we propose to develop an all-fiber isolator for 1 micron high power fiber lasers and amplifiers. An all-fiber isolator with multi-hundreds throughput power level will be demonstrated and delivered. Successful development of this proposed high Verdet constant fiber and all-fiber isolator will enable many new applications of high power fiber lasers, and revolutionize high power fiber laser and amplifier developments. BENEFIT: This proposed all-fiber isolator can be used for current DoD high power 1 micron fiber lasers and ...
Wausau, WI (August 28, 2017) - A recent study published in Lasers in Surgery and Medicine (LSM), the official journal of the American Society for Laser Medicine and Surgery, Inc. (ASLMS), was conducted to evaluate limb ischemia in peripheral arterial disease patients using laser speckle contrast imaging via a thermal load test. The research was conducted by Sotaro Katui MD; Yoshinori Inoue, PhD; Kimihiro Igari, PhD; Takahiro Toyofuku, PhD; Toshifumi Kudo; Phd; and Hiroyuki Uetake, PhD. Their manuscript titled, Novel assessment tool based on laser speckle contrast imaging to diagnose severe ischemia in the lower limb for patients with peripheral arterial disease was selected as Editors Choice in the September 2017 issue of LSM.. In the 21st century, peripheral arterial disease (PAD) has become a universal problem. It is estimated that globally, over 200 million people are affected by PAD, which continues to show increasing incidence rates. Appropriate and timely diagnosis of PAD can ensure ...
A new in situ instrument for gas-phase formaldehyde (HCHO), COmpact Formaldehyde FluorescencE Experiment (COFFEE), is presented. COFFEE utilizes nonresonant laser-induced fluorescence (NR-LIF) to measure HCHO, with 300 mW of 40 kHz 355 nm laser output exciting multiple HCHO absorption features. The resulting HCHO fluorescence is collected at 5 ns resolution, and the fluorescence time profile is fit to yield the ambient HCHO mixing ratio. Typical 1σ precision at ∼ 0 pptv HCHO is 150 pptv for 1 s data. The compact instrument was designed to operate with minimal in-flight operator interaction and infrequent maintenance (1-2 times per year). COFFEE fits in the wing pod of the Alpha Jet stationed at the NASA Ames Research Center and has successfully collected HCHO data on 27 flights through 2017 March. The frequent flights, combined with a potentially long-term data set, makes the Alpha Jet a promising platform for validation of satellite-based column HCHO.. ...
China CO2 Fiber UV Laser Marking Machine for Metal Non Metal Materials, Find details about China Machine Tool, Laser Engraving Machine from CO2 Fiber UV Laser Marking Machine for Metal Non Metal Materials - Guangzhou Hymson Laser Technology Co., Ltd.
A laser light irradiation apparatus used for medical treatment of tissues. According to a preferred embodiment, the apparatus comprises a probe, an optical fiber feeding laser light into the probe and a lead wire for detecting a temperature being inserted through and projecting from the probe. Then, the probe contains laser light scattering particles for uniform irradiation of the laser light against the tissues. Further, the probe is fabricated from a laser light tramissive synthetic material, and the fore end of a core of the optical fiber and the inserting part of the lead wire are in the synthetic material of the probe for easy molding for this apparatus.
The ML830® Cold Laser is a non-thermal cold laser lllt. The 830nm Laser is the deepest penetrating laser wavelength. The energy delivered promotes the process of photobiostimulation, lllt, lilt, infrared laser, a photochemical reaction that produces an increase in the cellular metabolism rate, expediting cellular repair and the stimulation of the immune, lymphatic and vascular systems. The Microlight ML830® is a handheld, battery-operated, noninvasive, light-emitting, medical device. ML830 Laser is FDA Approved for sale and use in the treatment of a variety of soft and connective tissue disorders as well as certain neurological disorders, this device is a low energy laser also known as a cold laser. Best Laser for humans and animals. Best laser for chiropractor, doctor, veterinary. Microlight Corp of America. Microlight ML830® Cold laser. 830 Laser for treatment of pain, inflammation, arthritis, carpal tunnel, sports injuries, rehab, muscle injury, ligament injury
The Laser-Induced Fluorescence (LIF) petroleum sensor is attached to a probe that is pushed into the ground with a truck-mounted hydraulic system (a cone penetrometer) to make real-time chemical measurements of contaminants, as part of the Site Characterization and Analysis Penetrometer System (SCAPS). The chemical sensor consists of a laser that fires short pulses of light into an optical fiber that runs through the probe. As the laser pulses pass into the soil through the probe window, petroleum contaminants in the soil respond by giving off a characteristic glow. This emitted light is carried back to the surface over a second fiber, and it is measured with a detector. The optical screening method provides a nearly continuous profile of contaminant distribution as the probe is pushed into the ground ...
Knowledge of the laser wavelength is essential in tunable IR laser spectroscopy. The scanning Michelson interferometer has the potential to compare the IR laser wavelength to a single, well-known calibration wavelength (e.g., HeNe laser) over a wide IR spectral range. In contrast to other recent work with scanning Michelson interferometers, we have added a phase-lock multiplier and counters to a $0.1 Cm^{-1}$ FTS laboratory interferometer to achieve an accuracy of $10^{-3}cm^{-1}$. This Idealab interferometer incorporated cats-eye mirrors, but its other features are probably representative of typical commercial interferometers. Measurements of a stable $CO_{2}$ laser have indicated a precision and calibratable accuracy of $0.001 cm^{-1}$ with $CO_{2}$ use of the HeNe laser monitor supplied with the interferometer. Achievement of the $0.0001 cm^{-1}$ precision and accuracy expected with the phase-lock multiplier is still under study as is the application of the wavemeter to the calibration of ...
An Overview:. It has become a very common these days to see dentists using laser technology. The use of lasers in dentistry started way back in the 1990s.. It has proven to be a safe and reliable method of treating a number of dental issues. In todays ever changing age of technical breakthroughs, laser has transformed dentistry from stone age to cutting edge.. It ensures that the dental treatment procedures that used to be lengthy, have now become less time-consuming and more effective. In a nutshell, the use of cutting edge laser technology in dentistry has made dental procedures more efficient than ever.. Use of Lasers in Dentistry:. Some of the uses for laser technology in dentistry are the following:. It can remove the discomfort caused by cold sores and cankers.. It can remove tissues that have overgrown due to medication.. It is used in the treatment of root canal infections.. It can reshape/remove bone and gum tissues while crown lengthening.. It helps in laser periodontal ...
Surface plasmons are photo-coupled quanta of electro excitation at the boundary of a metal and dielectric, which is a charge density wave of free electrons. Another important feature of surface plasmons resonance, in addition to the enhancement of electric field, is the ability to pass through surface structure smaller than incident laser wavelength and makes it have a potential to overcome the diffraction limit resulting in the breakthrough of nanotechnology. For surface plasmon resonance developing a mask with small feature size is vital. In this paper, mask fabrication by laser irradiation on self-assembly silica particles was described. Compared with the theoretical simulation, it is shown that self-assembly particle-assisted nanopatterning can fabricate a mask with very fine features effectively. With a proper particle size, laser wavelength and laser fluence, periodical structures generated can meet the requirement for surface plasmon use. © 2007 Elsevier B.V. All rights reserved ...
The current state-of-the-art in nanotip synthesis relies on techniques that utilize elaborate precursor chemicals, catalysts, or vacuum conditions, and any combination thereof. To realize their ultimate potential, synthesized nanotips require simpler fabrication techniques that allow for control over their final nano-morphology. We present a unique, dry, catalyst-free, and ambient condition method for creating densely clustered, flower-like, sodium oxide (Na2O) nanotips with controllable tip widths. Femtosecond laser ablation of a soda-lime glass substrate at a megahertz repetition rate, with nitrogen flow, was employed to generate nanotips with base and head widths as small as 100 and 20 nm respectively, and lengths as long as 10 μm. Control of the nanotip widths was demonstrated via laser dwell time with longer dwell times producing denser clusters of thinner nanotips. Energy dispersive X-ray analysis reveals that nanotip composition is Na2O. A new formation mechanism is proposed, involving an
NO laser-induced fluorescence (LIF) imaging and quantitative fuel distribution measurements in aport-fuel-injected 4-valve stratified-charge single-cylinder SI engine have been conducted using a tunable KrF excimer laser. The correlations between NO formation region and fuel distribution have been investigated for the horizontal stratification realized by fuel (iso-octane) injection in only one intake port. The NO LIF intensity is proportional to the exhaust NOx emissions. The strong NO LIF intensity region in expansion stroke corresponds to the location of the region with equivalence ratio (ϕ) between 0.8 and 1.1 in the stratified fuel distributions at spark timing. The exhaust NOx concentration is proportional to the area of region with ϕ =0.8 - 1.1. The relationship between the local NO LIF intensity and the local equivalence ratio ( ϕ L ) in the stratified-charge operation shows that NO is mainly formed in the local region with ϕ L=0.8 - 1.1, but that the maximum formation occurs at ϕ L ...
As many fiber laser marking factory and trading company apeard in fiber laser marking market. So how to choose a suitable fiber laser marking machine factory to be a good supplier is very important.. Jinan Xintian Technology Co.,Ltd is professional manufacturer of laser equipment, established in 2004.It is a professional manufacturer engaged in the research,development, production and service of Fiber laser marking machine,CO2 laser marking machine,Pneumatic marking machine,Laser engraving machine,Laser weldimachine, Laser cutting machine. We would be a good cooperator.. ...
Faster recovery times and better visual outcomes are among the early results of a corneal transplant pilot study underway at the University of Michigan Kellogg Eye Center. The focus of this two-year pilot program - called the Femtosecond Laser Assisted Keratoplasty study, or FLAK - is the use of the ultrafast or femtosecond laser in performing full thickness corneal transplants.. Researchers at Kellogg were first to discover in the early 1990s that the femtosecond laser, then used for industrial purposes, had great potential for eye surgeries that traditionally required a surgical blade or knife. Through joint efforts of faculty from Kellogg and the U-M College of Engineering, the femtosecond laser was further developed, and is widely used for refractive surgery. Now, experts hope for the same success in applying this exceptionally fast and precise laser to cornea transplant surgery.. We hope that with the use of the femtosecond laser, patients will have better vision, faster recovery of ...
Sampling of Tissues with Laser Ablation for bottom-up Proteomics: Comparison of Picosecond Infrared Laser (PIRL) and Microsecond Infrared Laser (MIRL)
Aiello, M. and McLaren, R.: Measurement of airborne carbonyls using an automated sampling and analysis system, Environ. Sci. Technol., 43, 8901-8907, https://doi.org/10.1021/es901892f, 2009. Apel, E. C., Olson, J. R., Crawford, J. H., Hornbrook, R. S., Hills, A. J., Cantrell, C. A., Emmons, L. K., Knapp, D. J., Hall, S., Mauldin III, R. L., Weinheimer, A. J., Fried, A., Blake, D. R., Crounse, J. D., St. Clair, J. M., Wennberg, P. O., Diskin, G. S., Fuelberg, H. E., Wisthaler, A., Mikoviny, T., Brune, W., and Riemer, D. D.: Impact of the deep convection of isoprene and other reactive trace species on radicals and ozone in the upper troposphere, Atmos. Chem. Phys., 12, 1135-1150, https://doi.org/10.5194/acp-12-1135-2012, 2012. ATom Science Team: ATom NASA DC-8 aircraft data archive, https://doi.org/10.3334/ORNLDAAC/1581, 2017. Cazorla, M., Wolfe, G. M., Bailey, S. A., Swanson, A. K., Arkinson, H. L., and Hanisco, T. F.: A new airborne laser-induced fluorescence instrument for in situ detection of ...
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Power Supply: this laser comes standard with an FDA power supply. If you would like the OEM power supply (no price difference), please call us or let us know in the special instructions of your order. The LED power supply is not available for this laser system.. Power Control: not available with MLL (low noise) lasers.. Modulation: not available for MLL (low noise) lasers.. Line Optics: for , = 75° spread, add $550. For , = 90° spread, add $600.. Fiber Coupling: MM fiber add $450; SM fiber add $730. (Click Here for More Fiber Coupling Info.) If you need fiber coupling, please call us or let us know in the special instructions of your order.. Eye Protection: our OLY-LSG-3 safety goggles block wavelengths of 190-540nm, providing eye protection against 355nm UV lasers. Always exercise great caution when using any high-power laser.. Price Match: If you find this laser from a retail store for less, please let us know and well try to match their price or better!. Note: these laser systems are ...
Kostyukova, N. Y., Boyko, A. A., Eryshin, E. Y., Kolker, D. B., Antipov, O. L., Eranov, I. D., Isaenko, L. I., Badikov, D. V. & Badikov, V. V., 1 июн 2019, 2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019. Institute of Electrical and Electronics Engineers Inc., 8873248. (2019 Conference on Lasers and Electro-Optics Europe and European Quantum Electronics Conference, CLEO/Europe-EQEC 2019).. Результат исследования: Публикации в книгах, отчётах, сборниках, трудах конференций › статья в сборнике материалов конференции › научная › рецензирование ...
The SemiNex lasers were chosen for their rugged design and established long term reliability. SemiNex provides 4-Pin lasers at a variety of wavelengths; however, for this application, 1550 nm was chosen due to the eye safety requirements. This achievement was the culmination of an effort that started in August 2013, when the modules were first qualified for launch.. Prior to their maiden voyage, the lasers underwent extensive qualification testing. The qualification included approximately one hundred billion laser pulses over a three week period. Throughout testing, 100% of the packaged laser diodes performed as expected, with no degradation in performance. SemiNex founder and Chief Executive Officer David Bean said, Having our off-the-shelf laser products perform well under such rigorous testing exemplifies our lasers high performance, quality and reliability.. SemiNexs lasers are also under evaluation and qualification for point-to-point, secure, space-based communications. Fiber-coupled ...
Background: Feline diabetes mellitus shares many similarities with human type 2 diabetes mellitus, including clinical, physiological and pathological features of the disease. The domestic cat spontaneously develops diabetes associated with insulin resistance in their middle age or later, with residual but declining insulin secretion. Humans and cats share largely the same environment and risk factors for diabetes, such as obesity and physical inactivity. Moreover, amyloid formation and loss of beta cells are found in the islets of the diabetic cat, as in humans. Altogether, the diabetic cat is a good model for type 2 diabetes in humans. The aims of the present study were to isolate feline islets using laser microdissection and to develop a quantitative method for detection of mRNA levels in islets of healthy and diabetic cats.Results: By using the laser microdissection technique, we were able to meticulously sample islets from both healthy and diabetic cats. Insulin staining of separate sections ...