A ductal cyst of the major lacrimal gland, or dacryops, is a rare clinical entity, encountered mainly in its palpebral lobe (1, 3, 4). Ductal cysts of the accessory lacrimal glands of Wolfring and Krause are even more uncommon than those of the major lacrimal gland and are rarely reported in the ophthalmologic literature (1, 2, 5-7). Clinically, cysts of the accessory gland develop insidiously and present as painless cystic masses of the lids. They are of variable size and are located in the previously described anatomic locations of the accessory glands. Most frequently, these cysts occur in patients with previous traumatic or inflammatory conditions of the conjunctiva, particularly in patients with trachoma (2, 5). Less commonly, a congenital anomaly of an excretory duct or alteration in the composition of secretions may be the cause of cyst formation (1). Histopathologically, these lesions are simple benign cysts lined by a layer of nonciliated cuboidal epithelial cells and occasional goblet ...
OBJECTIVE: The aim of this study was to report the clinicopathological features of 18 epithelial tumors of the lacrimal gland treated in a single institution. STUDY DESIGN AND SETTING: Clinical data and treatment were recorded and histological features reviewed. RESULTS: Twelve tumors (66.7%) were adenoid cystic carcinoma (ACC), 5 (27.8%) pleomorphic adenoma (PA), and 1 (5.5%) carcinoma ex pleomorphic adenoma. All patients with ACC presented with advanced clinical stage, and most were treated by wide surgical resection followed by adjuvant radiotherapy. No recurrence was observed in 4 cases of ACC; however, 7 patients died from persistence of disease or by local and/or distant recurrence. All PA patients were successfully treated by surgical resection. CONCLUSIONS: Epithelial lacrimal gland tumors are mainly PA and ACC, and malignancies are more common than benign tumors. Although ACC presented typically with advanced clinical stage, 33% of the patients survived without tumor recurrence or ...
Parathyroid Gland Involvement by Thyroid Cancer: Results from a Large Series of Thyroidectomies Performed in Two Italian University Hospitals and Review of the Literature. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Epiphora or excessive tearing is a significant disability for many affected patients diminishing their quality of life. There is a growing consensus that injection of Botulinum Toxin A (BTX-A) into the lacrimal gland provides relief in patients with hyperlacrimation secondary to aberrant regeneration of the 7th nerve, and limited evidence that it might help to reduce normal tear production in patients with epiphora from anatomic or functional outflow obstructions. BTX-A has been injected both transconjunctivally into the palpebral lobe of the lacrimal gland and transcutaneously into the orbital lobe. Both delivery routes have been successful in symptom relief with minimal complications. However, the effectiveness of transconjunctival versus transcutaneous injections has not been systematically compared. Also, whether the incidence of side effects is related to the dosage, concentration, or location of injection is unknown and has also not been systematically studied. The investigators plan to ...
A 55 year old woman presented to the ophthalmology department of the Schieffelin Leprosy Research and Training Centre with a left sided lacrimal mucocele. Since she also had a cataract that needed surgery, a dacryocystectomy was done in January 1999. During surgery, when the lacrimal sac was being dissected, a localised small area of black pigmentation was seen on the sac. The excised sac was sent for histopathological examination to rule out melanoma. There were no associated pigmentations on the skin overlying the sac or any fistulas in the region.. Histopathological examination of the lacrimal sac showed focal and diffuse collections of cells containing blackish-brown pigments in the stroma and the epithelial cells of the sac. Inflammatory cell collections consisting of lymphocytes, histiocytes, and plasma cells were also seen in the stroma (Fig 1). The intracellular pigment gave negative results when stained with Perls stain for haemosiderin3 but gave a positive result when stained with ...
The fossa of lacrimal sac is the vacant region between the frontal process of the maxilla and the lacrimal bone. It helps to lodge the lacrimal sac.. ...
List of diseases that include epiphora as a symptom. Any major, well-known medical conditions associated with epiphora are included below, listed alphabetically wit...
Krauses glands are small, mucous accessory lacrimal glands that are found underneath the eyelid where the upper and lower conjuctivae meet. Their ducts unite into a rather long sinus which open into the fornix conjunctiva. There are approximately forty Krause glands in the region of the upper eyelid, and around 6 to 8 in the region of the lower lid. The function of these glands are to produce tears which are secreted onto the surface of the conjuctiva. There are rare instances of tumors associated with Krauses glands. They usually occur as retention cysts in cicatricial conditions of the conjunctiva. Krauses glands are named after German anatomist Karl Friedrich Theodor Krause (1797-1868). Ciaccios glands Friedman, Neil J.; Kaiser, Peter K. (2007). Essentials of Ophthalmology. Elsevier Health Sciences. p. 7. ISBN 1416029079. Retrieved 11 November 2017. Lemp, Michael A.; Marquardt, Rolf (2013). The Dry Eye: A Comprehensive Guide. Springer Science & Business Media. p. 58. ISBN 9783642581304. ...
a. contains colourless hair b. contains accessory lacrimal glands c. is supplied by the superior medial palpebral arteries d. is innervated by the supratrochlear nerve e. is drained by the lymphatic drainage into the ...
Watery eyes (epiphora) tear persistently or excessively. Watery eyes can be due to excess tear production, inflammation of your eyes or inadequate drainage of your normal tears.
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Alacrima refers to a wide spectrum of lacrimal secretory disorders that are mostly congenital in origin. Symptoms of these disorders can range from a complete absence of tears to hyposecretion of tears; symptoms of rarer disorders include a selective absence of tearing in response to emotional stimulation but a normal secretory response to me...
The difference in the change of EDS score from baseline and the tear breakup time from baseline to follow-up, between study eyes in the study arm and study eyes in the control ...
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GMPPA - GMPPA - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector shRNA available for purchase from OriGene - Your Gene Company.
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Urethral caruncle is a soft, fleshy protrusion of the urethral lining from the urethral opening. The urethra is the tube that drains urine from the bladder.
Looking for online definition of accessory lacrimal glands in the Medical Dictionary? accessory lacrimal glands explanation free. What is accessory lacrimal glands? Meaning of accessory lacrimal glands medical term. What does accessory lacrimal glands mean?
Dacryocystocele or timo cyst is a benign, bluish-gray mass in the inferomedial canthus that forms as a result of a narrowing or obstruction of the nasolacrimal duct, usually during prenatal development. The prevalence of dacryocystocele is 1 in 3884 live births. Complications like swelling, watery eyes and infection might occur. While usually filled with sterile mucus, dacryocystoceles occasionally become infected. The nasolacrimal ducts drain the excess tears from our eyes into the nasal cavity. In dacryocystocele there this tube gets blocked on either end and as a result when mucoid fluid collects in the intermediate patent section it forms a cystic structure. The diagnosis can be made prenatally; routine obstetric ultrasound can identify the characteristic hypoechoic lesion inferior and medial to the globe. It is important to distinguish a dacrocystocele from the more serious encephalocele, which is a neural tube defect. A dacryocystocele can be diagnosed postpartum with a non-invasive ...
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TY - JOUR. T1 - Reconstructive options for the medial canthus and eyelids following tumor excision. AU - Czyz, Craig N.. AU - Cahill, Kenneth V.. AU - Foster, Jill A.. AU - Michels, Kevin S.. AU - Clark, Cooper M.. AU - Rich, Nicole E.. PY - 2011/1/1. Y1 - 2011/1/1. N2 - General principles provide the framework for eyelid and periorbital reconstruction following tumor excision. Eyelid tumors involving the medial canthus region and/or lacrimal system add to the complexity of reconstructive planning. The nature of the tumor, patient and tissue factors, and surgeon preference guide repair design choices. Reconstructive considerations and options following medial canthal tumor resection are described.. AB - General principles provide the framework for eyelid and periorbital reconstruction following tumor excision. Eyelid tumors involving the medial canthus region and/or lacrimal system add to the complexity of reconstructive planning. The nature of the tumor, patient and tissue factors, and surgeon ...
Tumors of the lacrimal gland constitute less than 5% of all biopsied orbital lesions [3, 4]. The most common epithelial malignancy is primary adenoid cystic carcinoma; adenocarcinoma is rare, representing only 5 to 7% of epithelial tumors of the lacrimal gland [2-6]. Because there is no specific histopathologic classification for lacrimal gland tumors, they are often classified according to the histological classification of salivary gland tumors with which they share many similarities [1, 3, 7].. This subtype of lacrimal gland, adenocarcinoma, was described for the first time in 1996 by Katz et al. [2]. Since then, most reports in the literature are case reports describing an aggressive clinical pattern and poor prognosis [1, 2, 8].. The tumor usually begins in the upper eyelid as a growth and is accompanied by clinical symptoms such as lid pseudoptosis, exophthalmos, dystopia, pain, and reduced visual acuity [4, 6].. The patients short life expectancy after surgical treatment for ...
GMPPA encodes the GDP-mannose pyrophosphorylase A protein (GMPPA). The function of GMPPA is not well defined, however it is a homolog of GMPPB which catalyzes the reaction that converts mannose-1-phosphate and guanosine-5-triphosphate to GDP-mannose. Previously, biallelic mutations in GMPPA were reported to cause a disorder characterized by achalasia, alacrima, neurological deficits, and intellectual disability. In this study, we report a female proband with achalasia, alacrima, hypohydrosis, apparent intellectual disability, seizures, microcephaly, esotropia, and craniofacial dysmorphism. Exome sequencing identified a previously unreported homozygous c.853+1G,A variant in GMPPA in the proband and her affected sister. Their unaffected parents were heterozygous, and unaffected brother homozygous wild type for this variant. Lymphoblast cells from the affected sisters showed complete loss of the GMPPA protein by Western blotting, and increased levels of GDP-mannose in lymphoblasts on high ...
Results 68 children (114 eyes) underwent balloon catheter dilatation and 37 children (60 eyes) had probing. Children who had balloon dilatation were significantly older: mean age 55.98±113.6 (range 9.0-728.0) months as opposed to 18.5±6.5 (range 7.0-60.0) months, p,0.01). After a mean follow-up time of 15.4 (range 4-32) months, 102 of 114 eyes were defined as successfully treated following balloon catheter dilatation (89.5% success rate) compared with 52 of 60 eyes following probing (86.7% success rate, p=0.581). Five of six patients (80%) in which the #00 probe could only hardly be inserted into the nasolacrimal duct because of firm bone resistance failed in the probing group, as opposed to only 2/10 (20%) in the balloon catheter group (p=0.03). ...
08/13/2016 Exam Type CAGE EXAM - Medical Rating is 3 C - MAJOR CONDITIONS , Behavior Rating is NONE, Weight 13.0 LBS.. 8/13/16 S/O-elevated third eyelids noted on rounds with serous nasal d/c and sneeze marks inc age A-URI P-move to isolation start doxycycline 50 mg/ml-1.3 ml PO SID x 10 days erythromycin OU BID x 7 days vet check in 7 and 10 days 8/6/16 VC - recheck eye BARH, does not allow handling Eyes clear, no epiphora/blepharospasm NSF A: Apparently healthy NO uri signs P: CTM while at MACC Prognosis excellent 08/04/16 18:41 BAR, becomes fractious with handling Mild dried brown discharge medial canthus OU, slightly blepharospastic with epiphora OS, mild debris AU (hx of ear mites), nndc OP 2/4 ddz PLN wnl H/L reg, no obvious murmur but growling a lot, ssp, lungs clear/eupenic ABD snp MSK amb x 4 Integ wnl BCS 7/9 UG f/s, spay scar noted Neuro a/a A:Epiphora OS mild Otherwise apparently healthy geriatric P: Recheck eye & for any URI signs in 2 days (cage exam ok, fractious) 8/2/16: SCAN ...
Eye Pain, Onset of Symptoms in the Fourth to Sixth Decade of Life, Unilateral Epiphora Symptom Checker: Possible causes include Recurrent Corneal Erosion, Foreign Body in the Eye, Central Corneal Ulcer. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.
Dacryocystitis is caused by inflammation of the lacrimal sac; this usually occurs in the setting of obstruction of the lacrimal apparatus. The obstruction may be congenital or secondary to infection, ... more
Nerve Biopsy Shows Hypomyelination & Schirmer Test Shows Alacrima Symptom Checker: Possible causes include Triple A Syndrome. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.
The lacrimal bones (French: os lacrymal) are extremely thin and delicate, quadrilateral in shape, and situated at the anterior part of the inner wall of the orbit. They are the smallest of the facial bones.. The outer or orbital surface is divided by a vertical ridge into two unequal portions. The anterior smaller portion is deeply grooved to form the lacrimal sulcus, which lodges the lacrimal sac and forms the commencement of the lacrimal duct. The portion behind the ridge is smooth, and forms part of the inner wall of the orbit. The ridge gives origin to the tensor tarsi muscle, and terminates inferiorly in a hook-like process, the hamulus, which curves forward to articulate with the lacrimal tubercle of the maxilla and completes the superior orifice of the lacrimal canal. The inner surface is in relation with the two anterior cells of the ethmoid (lacrimo-ethmoid), and forms part of the infundibulum. The superior border is short, and articulates with the internal angular process of the ...
D04.12 is a non-billable code, consider using a code with a higher level of specificity for a diagnosis of carcinoma in situ of skin of left eyelid, including canthus.
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This article describes the anatomy, function, and clinical importance of the lacrimal gland. Learn now at Kenhub how the lacrimal gland is functioning.
Philippine General Hospital, University of the Philippines Manila. Objective. This study aims to determine the prevalence and pattern of thyroid gland involvement in advanced laryngeal squamous cell carcinoma and to identify factors associated with its development.. Method. Records of 118 patients who underwent laryngectomy with thyroidectomy for advanced laryngeal squamous cell carcinoma in a tertiary government hospital from January 2010 to August 2015 were reviewed. Demographic, clinical and histopathology data were obtained. The relationship of the laterality of primary tumor bulk and lobe involvement was analyzed using Fischers exact test. The association between thyroid gland invasion and other factors was analyzed using logistic regression.. Results. Thyroid gland involvement was found in 11% of the patients via direct spread in 92.3%. Single lobe involvement accounted for 61.5% of cases. There is a tendency for laryngeal squamous cell carcinoma to invade the thyroid lobe ipsilateral to ...
Orbital and Adnexal Oncology -- Primary orbital tumors -- Metastatic orbital tumors -- Orbital tumors extending from periocular structures (brain, paranasal sinuses) -- Lacrimal gland tumors -- Primary eyelid cancers -- Conjunctival tumors -- Intraocular Tumors -- Retinoblaastoma -- Uveal melanoma -- Intraocular lymphoma -- Uveal metastatic lesions -- Retinal vascular tumors -- Ocular Surface Disease and Cornea -- Graft-vs-Host disease -- Cataract surgery in cancer patients -- Radiation-induced ocular surface disease -- Neuro-ophthalmic manifestations of Cancer -- Cranial neuropathies -- Skull based tumors -- Optic nerve tumors -- Leptomeningeal disease -- Cancer-associated retinopathy -- Neurofibromatosis -- Other optic nerve maladies in cancer patients -- Oculoplastic Surgery and Periocular Reconstructive Surgery in Cancer Patients -- Eyelid defects -- Nasolacrimal duct blockage/ Lacrimal surgery -- Eyelid malposition -- Orbital reconstruction -- Enucleation /evisceration /exenteration / ...
Excess tears are drained by the nasolacrimal duct system (NLDS) which consists of superior and inferior canaliculi, a lacrimal sac and a lacrimal duct. The canaliculi openings at the medial lid margins are called puncta. The superior and inferior canaliculi join medially to form a common canaliculus which enters the posterior wall of the lacrimal sac. The nasolacrimal duct drains the sac into the nasal cavity below the inferior turbinate. Obstruction of the NLDS causes epiphora (excessive tearing) and eventually dacryocystitis (inflammation of the lacrimal sac). The etiology of obstruction may be congenital or acquired, including inflammation, infection, trauma or neoplasm. The most common infectious organisms in acute congenital and acquired dacryocystitis are Streptococcus pneumoniae and Staphylococcus aureus respectively. Untreated dacryocystitis can result in orbital cellulitis, corneal involvement, lacrimal sac mucocele and, rarely, orbital abscess. Also keep in mind that lesions arising ...
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QUESTION: A physician intubated the nasolacrimal duct with a silicone stent and performed an incision and drainage (I&D) and curretage of the canaliculus lower lid. Note the following documentation: Significant drainage and granular material was expressed from the left lower lid canaliculus and sent for culture. A #2 Bowman probe could be introduced into the left lower nasolacrimal duct without significant resistance. An 11 blade was used to make a stab incision into the canaliculus proximal to the punctum. A currette was introduced into the canaliculus to remove the material. A small incision was also made into the punctum to enlarge the punctum in order to fit the curette, and this area was drained as well. The nasal packing was removed. A Crawford tube was introduced into the superior nasolacrimal system and retrieved from beneath the inferior turbinate using the Crawford hook. The Crawford tube was then introduced into the inferior punctum and the inferior canalicular and nasolacrimal duct and
To elucidate the potential etiological role of RUNX3 in the development of salivary gland adenoid cystic carcinoma (ACC), we analyzed the methylation status of RUNX3 in a series of 114 ACC tissues and 3 ACC cell lines. Results showed that the methylated rate of RUNX3 was 50.9 and 3.5% in the 114 ACC samples and the corresponding normal salivary glands, respectively, achieving a significant difference ( ...
The congenital problems that can affect the nasolacrimal system are outlined below. Dacryostenosis A very common condition in which the extreme end of the nasolacrimal duct underneath the inferior turbinate fails to complete its canalization in the newborn period and may produce clinical symptoms in 2-4% of newborns.
Dacryolithiasis occurs in patients with chronic underlying dacryocystitis. Denuded epithelial cells clump together with exudated proteins and debris, forming a cast in the lacrimal sac. With time, the material eventually mineralizes, most typically with calcium (2). Dacryoliths are typically found in the setting of chronic infections with superimposed fungal colonization. They are found in up to 30% of patients with chronic dacryocystitis (3), are difficult to identify on conventional radiographs, and appear as round or oval filling defects on dacryocystography. On a CT scan, dacryoliths are characterized by focal areas of high attenuation within a soft-tissue attenuation mass in the region of the lacrimal sac (4). They may have a peripheral rim of calcification, giving a "rice kernel" appearance.. Dacryocystitis is characterized by epiphora, erythema, and edema in the region of the medial epicanthus and lacrimal puncta as the result of an infection of the nasolacrimal sac. Often there is ...
The lacrimal (or nasolacrimal) sac forms part of the nasolacrimal drainage apparatus. It is located in the preseptal part of the orbit. Gross anatomy The lacrimal sac lies in the lacrimal fossa on the inferomedial aspect of the bony orbit betw...
title:Microbiologic Spectrum of Acute and Chronic Dacryocystitis. Author:Abha Gahlot, Shashi Prasad, Manisha Singh, Bhargav Kotadia, Saloni Garg. Keywords:Epiphora, Dacrocystitis, Bacteriology. Type:Original Article. Abstract:Introduction: The aim of this study is to report the microbiological spectrum of dacryocystitis and the antibiotic sensitivity patterns of the organisms. It was a prospective study done at Department of Ophthalmology, Dr. D. Y. Patil Medical College and Hospital, Pimpri, Pune between 1st May to 30th June 2015 on 42 cases of clinically established dacryocystitis. Methodology: Patients were diagnosed with dacryocystitis and on the presence of a pus-filled lacrimal sac and peri lacrimal tissues for acute dacryocystitis. Chronic dacryocystitis patients were diagnosed by ROPLAS Test and sac syringing and were reviewed for demographic and microbiological profile.The culture results, organisms isolated, and their antibiotic sensitivity were studied. Results: In this study 42 ...
A blocked tear duct is called dacryostenosis. It may also be called a congenital lacrimal duct obstruction. Congenital means that your baby is born with it. Tears help clean and lubricate your babys eyes. Theyre made in the lacrimal gland. This is located under the bone of the eyebrow. Tears from the lacrimal gland go into the eye through tiny ducts along the eyelid. Tears drain through 2 small openings at the inner corner of the eyelids. They then drain into a larger passage from the eye to the inside of the nose. This is called the tear duct (nasolacrimal duct).. ...
Learn more about Lacrimal Duct Stenosis at Mountain Orthopedic Trauma Surgeons at Swedish DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
Once the more serious causes for epiphora have been eliminated, it is necessary to determine if proper and adequate tear drainage is occurring. A thorough ocular examination is performed, paying special attention to the tear ducts and nearby tissues, and looking for signs of inflammation or other abnormalities. The facial anatomy of the dog may play a role in this condition. Some breeds have flat or "squished-in" faces that do not allow the tear film to drain properly. In these patients, the tear film fails to enter the duct and simply rolls off the face. In other cases, the hair around the eyes physically obstructs the entrance to the tear ducts, or debris or a foreign body forms a plug within the duct and prevents drainage of tears.. One of the simplest tests to assess tear drainage is to place a drop of fluorescein stain in the eye, hold the patients head slightly downward, and watch for drainage into the nose. If the drainage system is functioning normally, the eye stain should be seen in ...
Looking for online definition of caruncle in the Medical Dictionary? caruncle explanation free. What is caruncle? Meaning of caruncle medical term. What does caruncle mean?
Special Senses. Chapter 8. Eye Anatomy. Accessory Structures Eyelids Commissures Palpebral fissure Tarsal gland Lacrimal Apparatus Lacrimal gland Lacrimal canaliculi Lacrimal sac Nasolacrimal duct. Extrinsic Eye Muscles. Layers of the Eyeball. Fibous Layer: Schlera and Cornea Slideshow 2647055 by conner
Watery eyes are also known as epiphora or tearing, which is a condition that results in an overflow of tears. Usually this occurs without any clear explanation. As a result, there is insufficient tear film drainage from the eye(s) that cause it to overflow on the face rather than through the nasolacrimal system.. Tears serve an important purpose to the eyes such as keeping your eyes lubricated, and keeping away dust and/or foreign particles. It also protects your immune system from any other infection. Without the right balance of water and oils, your eyes can become too dry. However, it is very common to temporarily produce excess tears when being emotional, coughing, laughing and vomiting. Among these, several other causes can result in watery eyes, too, such as:. ...