The precise movement of the cochlear basilar membrane (BM) stimulates the sensory hair cells during auditory transduction. However, the molecular composition of the BM that confers its specialized properties of support and elasticity is poorly understood. A differential screen of cochlear RNA from deaf mice lacking thyroid hormone receptor ß was used to identify a sequence encoding a secreted protein, which is abundant in the BM and is expressed at low levels in the heart, lung, and brain. The protein possesses several domains for protein interactions and is related to emilin (elastin microfibril interface-located protein) previously isolated from aorta. This cochlear emilin-2 mRNA is expressed in the tympanic border cells underlying the BM and an antibody detected protein in the extracellular matrix surrounding the collagenous fibers in the BM. These results identify emilin-2 as a major BM component and suggest that it contributes to the developmental assembly or function of the BM.. ...
Italian company Nobili combines fashion and function in this awesome 360-degree rotation kitchen faucet. The new 2010 Zoom kitchen mixer by designer Nilo
basis of record De Grave, S. & C.H.J.M. Fransen. (2011). Carideorum catalogus: the recent species of the dendrobranchiate, stenopodidean, procarididean and caridean shrimps (Crustacea: Decapoda). Zool. Med. Leiden. 85(9): 30.ix.2011: 195-589 figs 1-59. (look up in IMIS) [details] Available for editors ...
additional source De Grave, S. & C.H.J.M. Fransen. (2011). Carideorum catalogus: the recent species of the dendrobranchiate, stenopodidean, procarididean and caridean shrimps (Crustacea: Decapoda). Zool. Med. Leiden. 85(9): 30.ix.2011: 195-589 figs 1-59. (look up in IMIS) [details] Available for editors ...
by Carlotta, Franchi and Raffaella, Rossio and Ilaria, Ardoino and Alessandro, Nobili and Mannuccio, Mannucci Pier and Mannucci, Pier Mannuccio and Nobili, Alessandro and Pietrangelo, Antonello and Perticone, Francesco and Licata, Giuseppe and Violi, Francesco and Corazza, Gino Roberto and Corrao, Salvatore and Marengoni, Alessandra and Salerno, Francesco and Cesari, Matteo and Tettamanti, Mauro and Pasina, Luca and Franchi, Carlotta and Franchi, Carlotta and Cortesi, Laura and Tettamanti, Mauro and Miglio, Gabriella and Tettamanti, Mauro and Cortesi, Laura and Ardoino, Ilaria and Novella, Alessio and Prisco, Domenico and Silvestri, Elena and Emmi, Giacomo and Bettiol, Alessandra and Caterina, Cenci and Biolo, Gianni and Zanetti, Michela and Guadagni, Martina and Zaccari, Michele and Chiuch, Massimiliano and Vanoli, Massimo and Grignani, Giulia and Pulixi, Edoardo Alessandro and Bernardi, Mauro and Bassi, Silvia Li and Santi, Luca and Zaccherini, Giacomo and Lupattelli, Graziana and Mannarino, ...
Valerio, G., Maffeis, C., Saggese, G., Ambruzzi, M. A., Balsamo, A., Bellone, S., Bergamini, M., Bernasconi, S., Bona, G., Calcaterra, V., Canali, T., Caroli, M., Chiarelli, F., Corciulo, N., Crinò, A., Di Bonito, P., Di Pietrantonio, V., Di Pietro, M., Di Sessa, A., Diamanti, A. & 38 others, Doria, M., Fintini, D., Franceschi, R., Franzese, A., Giussani, M., Grugni, G., Iafusco, D., Iughetti, L., Lamborghini, A., Licenziati, M. R., Limauro, R., Maltoni, G., Manco, M., Reggiani, L. M., Marcovecchio, L., Marsciani, A., Del Giudice, E. M., Morandi, A., Morino, G., Moro, B., Nobili, V., Perrone, L., Picca, M., Pietrobelli, A., Privitera, F., Purromuto, S., Ragusa, L., Ricotti, R., Santamaria, F., Sartori, C., Stilli, S., Street, M. E., Tanas, R., Trifiró, G., Umano, G. R., Vania, A., Verduci, E. & Zito, E., Jul 31 2018, In : Italian Journal of Pediatrics. 44, 1, p. 1-21 21 p.. Research output: Contribution to journal › Review article ...
Marizzoni M, Antelmi L, Bosch B, Bartrés-Faz D, Müller BW, Wiltfang J, Fiedler U, Roccatagliata L, Picco A, Nobili F, Blin O, Bombois S, Lopes R, Sein J, Ranjeva JP, Didic M, Gros-Dagnac H, Payoux P, Zoccatelli G, Alessandrini F, Beltramello A, Bargalló N, Ferretti A, Caulo M, Aiello M, Cavaliere C, Soricelli A, Salvadori N, Parnetti L, Tarducci R, Floridi P, Tsolaki M, Constantinidis M, Drevelegas A, Rossini PM, Marra C, Hoffmann KT, Hensch T, Schönknecht P, Kuijer JP, Visser PJ, Barkhof F, Bordet R, Frisoni GB, Jovicich J; PharmaCog Consortium... Hum Brain Mapp. 2015 Sep;36(9):3516-27. doi: 10.1002/hbm.22859. ...
Questionnaire items in the social attitude domain are particularly prone to be affected by individual differences in scale usage, notably, acquiescent responding (yea-saying vs. nay-saying tendency). Item-pairs consisting of one forward- and one reverse-keyed item, thus balanced as almost all these pairs are, remove most effects of differences in acquiescence, and so produce more clearly interpretable downstream results in multivariate analyses. ...
A variable used in determining a suitable step length for the forward- difference approximation of the Jacobian (for Dfun=None). Normally the actual step length will be sqrt(epsfcn)*x If epsfcn is less than the machine precision, it is assumed that the relative errors are of the order of the machine precision.. ...
In many studies of localizing 3D sound via headphones, static sounds and individualized HRTFs were used. When the dynamic cue and nonindividualized HRTFs are used, 3D sound presentation time for accurate localization has been interesting, because moving the head toward the direction of the sound will take time. This paper presents an experimental study on subjects reaction time for localizing the 3D sound presented via headphones. There were 31 volunteers (16 males and 15 females). The...
Bos, I., Vos, S. J., Froelich, L., Kornhuber, J., Wiltfang, J., Maier, W., Peters, O., Ruether, E., Engelborghs, S., Niemantsverdriet, E., De Roeck, E. E., Tsolaki, M., Freund-Levim, Y., Johannsen, P., Vandenberghe, R., Lleo, A., Alcolea, D., Frisoni, G. B., Galluzzi, S., Nobili, F. & 26 others, Morbelli, S., Drzezga, A., Didic, M., van Berckel, B. N., Salmon, E., Bastin, C., Dauby, S., Santana, I., Baldeiras, I., de Mendonca, A., Silva, D., Wallin, A., Nordlund, A., Coloma, P. M., Wientzek, A., Alexander, M., Novak, G. P., Gordon, M. F., Wallin, A. K., Hampel, H., Soininen, H., Herukka, S-K., Scheltens, P., Verhey, F. R., Visser, P. J. & Alzheimers Disease Neuroimaging Initiative, Aug 2017, In : Neurobiology of Aging. 56, p. 33-40 8 p.. Research output: Contribution to journal › Article › Academic › peer-review ...
Reijs, B. L. R., Vos, S. J. B., Soininen, H., Lötjonen, J., Koikkalainen, J., Pikkarainen, M., Hall, A., Vanninen, R., Liu, Y., Herukka, S-K., Freund-Levi, Y., Frisoni, G. B., Frölich, L., Nobili, F., Rikkert, M. O., Spiru, L., Tsolaki, M., Wallin, Å. K., Scheltens, P., Verhey, F. & 1 others, Visser, P. J., 2017, In : Journal of Alzheimers Disease. 60, 4, p. 1387-1395. Research output: Contribution to journal › Article › Scientific › peer-review ...
50 per ogni tribù Nella boulè erano rappresentati tutti gli interessi delle diverse classi di Atene democrazia Difende gli interessi non di pochi privilegiati, ma della massa dei suoi cittadini (Tucidide) isonomia e isegoria leggi egualmente valide e per nobili e per plebei conciliando una retta giustizia per entrambi (Solone) formale ugualianza dove le tradizionali appartenenze familiari perdevano peso Aristotele: governare ed essere governati a turno: alternanza delle cariche ...
The high resolution lunar global images acquired by ChangE-2 (CE-2) CCD camera orbiter are of great importance for lunar science research as well as preparation of the landing and surface operation of ChangE-3 (CE-3) lunar rover. In this paper, a rigorous geometric model of CE-2 CCD camera is developed based on the push-broom imaging principle. A self-calibration bundle adjustment (SCBA) method is proposed to eliminate the inconsistencies between forward- and backward-looking images, which are caused by the inaccuracy of exterior orientation (EO) parameters and the uncertain relationship between the two CCD line arrays of the camera. The interior orientation (IO) model is refined by adding several additional parameters and the EO parameters are fitted by a third-order polynomial model. Strategies for ensuring the robustness and reliability of the solution are also adopted, including EO pseudo observations selection, reasonable weight determination, and truncated singular value decomposition ...
Figure 5. Hematopoietic cell lung infiltrates in response to S180-Fluc cell challenge. A/J and BTBRT mice were injected with S180-Fluc cells or with media alone (n = 5 per group) and whole lungs were digested 1 d after injection and stained for flow cytometry analysis. A, live cells were selected by forward- and side-scatter, and populations of dendritic cells (CD11b+ CD11c+), monocytes/macrophages (CD11b− CD11c+), helper T cells (CD4+ CD90+), CTLs (CD8+ CD90+), neutrophils (Ly6G+ GR1+), and NK cells (NK1.1+ CD90−) were quantified. B, strain-dependent differences in CD4+ helper T cells at 1 d after delivery of S180-Fluc cells. C and D, induction of CD11b− CD11c+ dendritic cells in response to S180-Fluc cells at 1 and 7 d after injection. E, T-cell depletion enhances pulmonary metastasis in BTBRT mice. BTBRT mice were injected i.p. with anti-CD4 and anti-CD8 antibodies or control normal goal IgG (250 μg/mouse, five animals per group) every 2 and 4 d before S180-Fluc cell (7 × 105) tail ...
On March 30, 2017, Aldeyra Therapeutics, Inc. ( Aldeyra ) issued a press release and is holding a conference call regarding its financial results for the year ended December 31, 2016. The press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated by reference herein. Various statements to be made during the conference call are forward-looking statements under the securities laws, including, but not limited to, statements regarding Aldeyra s plans for its product candidates. In some cases, you can identify forward looking statements by terms such as, but not limited to, may, might, will, objective, intend, should, could, can, would, expect, believe, anticipate, project, target, design, estimate, predict, potential, plan or the negative of these terms, and similar expressions intended to identify forward-looking statements. Such forward- looking statements are based upon current expectations that involve risks, changes in circumstances, assumptions and ...
On May 15, 2017, Aldeyra Therapeutics, Inc. ( Aldeyra ) issued a press release and is holding a conference call regarding its financial results for the quarter ended March 31, 2017. The press release is furnished as Exhibit 99.1 to this Current Report on Form 8-K and is incorporated by reference herein. Various statements to be made during the conference call are forward-looking statements under the securities laws, including, but not limited to, statements regarding Aldeyra s plans for its product candidates. In some cases, you can identify forward looking statements by terms such as, but not limited to, may, might, will, objective, intend, should, could, can, would, expect, believe, anticipate, project, target, design, estimate, predict, potential, plan or the negative of these terms, and similar expressions intended to identify forward-looking statements. Such forward- looking statements are based upon current expectations that involve risks, changes in circumstances, assumptions and ...
Well-. 16 yrs ago diagnosed with hashimotos- scan/biopsy- etc. Unfortunatley could not put me on meds- as swing from hypo/hyper- HELL!. fast forward- had baby- OB noticed lumps- which knew I had but was told less chance cancer with HASHIMOTOS (not true I now find out)- have U/s and then see endo who sends me to surgeon- takes it out. NOW finds two tumors- follicular variant- architecture- follicular- partially encapsulated and capsular involvement. Also two suspicious lymph nodes- negative.. Fiance was to "watch" baby so I could have RAI/WBS- but said he couldnt get vacation for 4 months. (ON holiday) I was cooking for his friends/family who were about to arrive and he went off on me for getting drops water on his kitchen table. (He had asked me to go away that day- to a special place of ours ... as this holiday date was a special anniversary of sorts- baby girl bday who died- and I so needed a vacation- and then he invited people over.) About to cry as write this. Me and baby went to park that ...
Autoimmune liver disease in children. Yachha SK1, Srivastava A, Chetri K, Saraswat VA, Krishnani N. J Gastroenterol Hepatol. 2001 Jun;16(6):674-7.. http://www.ncbi.nlm.nih.gov/pubmed/11422621. Autoimmune hepatitis, one disease with many faces: Etiopathogenetic, clinico-laboratory and histological characteristics.. Nikolaos K Gatselis, Kalliopi Zachou, George K Koukoulis, George N Dalekos. World J Gastroenterol 2015 January 7; 21(1): 60-83.. http://www.ncbi.nlm.nih.gov/pubmed/25574080. Autoimmune hepatitis in children: an overview of the disease focusing on current therapies.. Della Corte C1, Sartorelli MR, Sindoni CD, Girolami E, Giovannelli L, Comparcola D, Nobili V.. Eur J Gastroenterol Hepatol. 2012 Jul;24(7):739-46.. http://www.ncbi.nlm.nih.gov/pubmed/22495399. Fulminant hepatic failure of autoimmune aetiology in children.. Di Giorgio A1, Bravi M, Bonanomi E, Alessio G, Sonzogni A, Zen Y, Colledan M, DAntiga L. J Pediatr Gastroenterol Nutr. 2015 ...
TY - JOUR. T1 - Association between Later Life Lifestyle Factors and Alzheimers Disease Biomarkers in Non-Demented Individuals. T2 - A Longitudinal Descriptive Cohort Study. AU - Reijs, Babette L.R.. AU - Vos, Stephanie J.B.. AU - Soininen, Hilkka. AU - Lötjonen, Jyrki. AU - Koikkalainen, Juha. AU - Pikkarainen, Maria. AU - Hall, Anette. AU - Vanninen, Ritva. AU - Liu, Yawu. AU - Herukka, Sanna-Kaisa. AU - Freund-Levi, Yvonne. AU - Frisoni, Giovanni B.. AU - Frölich, Lutz. AU - Nobili, Flavio. AU - Rikkert, Marcel Olde. AU - Spiru, Luiza. AU - Tsolaki, Magda. AU - Wallin, Åsa K.. AU - Scheltens, Philip. AU - Verhey, Frans. AU - Visser, Pieter Jelle. PY - 2017. Y1 - 2017. N2 - Background: Lifestyle factors have been associated with the risk of dementia, but the association with Alzheimers disease (AD) remains unclear. Objective: To examine the association between later life lifestyle factors and AD biomarkers (i.e., amyloid-ß 1-42 (Aß 42) and tau in cerebrospinal fluid (CSF), and ...
TY - JOUR. T1 - Hippocampal epileptogenesis in autoimmune encephalitis. AU - Romoli, M.. AU - Krashia, P.. AU - Sen, A.. AU - Franciotta, D.. AU - Gastaldi, M.. AU - Nobili, A.. AU - Mancini, A.. AU - Nardi Cesarini, E.. AU - Nigro, P.. AU - Tambasco, N.. AU - Mercuri, N.B.. AU - Parnetti, L.. AU - Di Filippo, M.. AU - DAmelio, M.. AU - Irani, S.R.. AU - Costa, C.. AU - Calabresi, P.. N1 - cited By 0. PY - 2019. Y1 - 2019. U2 - 10.1002/acn3.50919. DO - 10.1002/acn3.50919. M3 - Articolo. VL - 6. SP - 2261. EP - 2269. JO - Annals of Clinical and Translational Neurology. JF - Annals of Clinical and Translational Neurology. SN - 2328-9503. IS - 11. ER - ...
The primary role for the Director of Development for the University of South Florida Foundation and College of Marine Science is to secure local, regional and national resources to move the following priorities of the College of Marine Science forward- 1) Endowed Chairs and Professorships, 2) Endowed Student Fellowships and 3) Sustainable Outreach and Education Programs. In addition, the Director of Development works closely with the Dean to cultivate, develop and sustain relationships with existing and potential donors and partners with the University of South Florida and College of Marine Science. The Director of Development also seeks out ways for Faculty and Graduate Students to share their findings with the broader community and demonstrate how the College of Marine Science is a global leader in applying science to societys needs through research, service and training of future scientists.. Four Quick Facts About Yourself. ...
Core Lab offers an Agilent Bioanalyzer platform for a wide range of applications with its lab-on-a-chip technology, high resolution and quantification of RNA and DNA, and protein analysis. Those applications can be also supported by the NanoDrop One or Qubit spectrophotometers.. The recently acquired Odyssey CLx imaging system by Li-Core provides infrared imaging support for all Western Blots applications with Image Studio software.. Core Lab is equipped with a Microplate Absorbance reader - iMark by BioRad with a wavelength range of 400-750 nm; a high performance solution for various immunoassays with colorimetric substrates as well as various protein assays.. For all cell sorting needs Core Lab offers BioRad S3e fully automated cell sorter, with two lasers and up to four fluorescence detectors, plus forward- and side-scatter detectors.. Lastly, Core Lab offers a gel-imaging system - BioRads GelDoc EZ. This compact and automated gel imaging instrument enables production of publication-quality ...
Its time to renew. It really is "time!" Phillip Zimbardo gives me the key to the new Spinning Babies in The Time Paradox. Get his 2 minute over view is on Phillip Zimbardos TED talk. The talk gets interesting at the marshmallows, so hang in there. Our time metaphors keep us moving forward- or leaves us stuck in the past. How we see time is how we live our lives. How can I resist the marshmallow and improve my time perspective? Incorporating his Optimal Temporal Mix will definitely improve the reach of Spinning Babies. At least it will stop me eating so many marshmallows ...
1. Noctuid moths of several species were mounted at the tip of a tower of fine tubing in acoustic free space. Recordings were made of the intensity of a brief pulse of ultrasound necessary to produce a constant tympanic nerve response for any angle of sound presentation relative to the moths body axis. Such plots of intensity versus angle were made with the wings held in several postures approximating those assumed in normal flight.. 2. The data indicate that sound intensity reaching the tympanic organ can vary by as much as 40 db. depending upon: (a) the position of a sound source relative to the moths body axis, and (b) the position of its wings.. 3. With wings above the horizontal plane each ear reports sounds c. 20-40 db. louder on the ipsilateral side than on the contralateral side. With wings below the horizontal, the lateral asymmetries are replaced by a dorsoventral asymmetry in which each ear reports sounds coming from below the body c. 10-25 db. louder than sounds coming from ...
by Vos, Stephanie J. B and Verhey, Frans and Frölich, Lutz and Kornhuber, Johannes and Wiltfang, Jens and Maier, Wolfgang and Peters, Oliver and Rüther, Eckart and Nobili, Flavio and Morbelli, Silvia and Frisoni, Giovanni B and Drzezga, Alexander and Didic, Mira and van Berckel, Bart N. M and Simmons, Andrew and Soininen, Hilkka and Kłoszewska, Iwona and Mecocci, Patrizia and Tsolaki, Magda and Vellas, Bruno and Lovestone, Simon and Muscio, Cristina and Herukka, Sanna-Kaisa and Salmon, Eric and Bastin, Christine and Wallin, Anders and Nordlund, Arto and de Mendonça, Alexandre and Silva, Dina and Santana, Isabel and Lemos, Raquel and Engelborghs, Sebastiaan and Van der Mussele, Stefan and Freund-Levi, Yvonne and Wallin, Åsa K and Hampel, Harald and van der Flier, Wiesje and Scheltens, Philip and Visser, Pieter Jelle and The Alzheimers Disease Neuroimaging Initiative and Alzheimers Dis Neuroimaging Initi and Alzheimers Disease Neuroimaging Initiative and Institute of Neuroscience and ...
Kiluchi, T. (1995) Gap junction in the rat cochlea immunohisto-chemical and ultrastructural analysis. Anatomy and Embryology, 2, 101-118.
Maturation of neurotransmission in the developing rat cochlea: immunohistochemical evidence from differential expression of synaptophysin and synaptobrevin 2
Cariogram outcome after 90 days of oral treatment with Streptococcus salivarius M18 in children at high risk for dental caries: results of a randomized, controlled study Francesco Di Pierro,1 Alberto Zanvit,2 Piero Nobili,2 Paolo Risso,3 Carlo Fornaini4 1Scientific Department, Velleja Research, 2Stomatology Institute, Milan, Italy; 3Department of Health Science, University of Genoa, Genoa, Italy; 4Teleo Laboratory, Faculty of Dentistry, University of Nice, Nice, France Abstract: Dental caries is the most common chronic disease of childhood. Cariogram is a well-recognized algorithm-based software program based on different caries-related risk factors and intended to aid clinicians in performing more objective and consistent dental caries risk assessments. This type of approach precedes the diagnosis of caries and allows the dentist to identify at-risk patients and then take appropriate preventive measures before caries develop further. One of the etiological factors favoring the development of dental
Superior semicircular canal dehiscence (SCD) is a condition in which the bone overlying the superior semicircular canal is absent. The clinical presentation of SCD is highly variable and may include both auditory and vestibular manifestations. The more common symptoms include autophony, sound or pressure induced vertigo, hypersensitivity to sound, and low frequency conductive hearing loss. Repair can be accomplished via either transmastoid or middle fossa approaches, with numerous materials used to either plug or resurface the canal. Herein, we describe our resurfacing technique using a loose areolar tissue-bone pâté-loose areolar tissue sandwich through a middle fossa approach. DOI#: http://dx.doi.org/10.17797/kcwvab3b7r
Objective- To compare the in vitro elution characteristics of amikacin and cefazolin from polymethylmethacrylate (PMMA) alone and in combination.. Study Design- A prospective, controlled, experimental study.. Methods- Three aliquots of 6 g sterile PMMA were measured and to them added (1) 750 mg amikacin; (2) 1050 mg cefazolin; and (3) 750 mg amikacin and 1050 mg cefazolin. Ten beads of each antimicrobial/PMMA combination were placed in 5 mL phosphate-buffered saline (PBS) at pH 7.4 and room temperature with constant agitation. PBS was sampled at 15 time points between 1 hour and 30 days. Amikacin concentrations were determined by fluorescence polarization immunoassay and cefazolin concentrations by high-performance liquid chromatography.. Results- Amikacin and cefazolin eluted at concentrations greater than 8 and 4 times, respectively, above the minimum inhibitory concentration (MIC) for susceptible bacteria over 30 days. Co-elution of the antibiotics resulted in a greater rate and proportion of ...
In my practice devoted to facial plastic surgery, the primary procedure I perform is rhinoplasty, or "nose job." The goal of this surgery is pretty straight forward- to help make the nose more attractive, assuring that it "fits" with the rest of the facial features. While often performed for purely elective cosmetic purposes, occasionally there is a history of trauma where the nose may have been fractured or broken in the past.. No matter what ones cosmetic displeasure is with the nose, the nose has a primary function-to allow the unobstructed passage of air into the lungs, and humidify and filter that air. The function of the nose must never be compromised, otherwise one will have a very unhappy patient who is unable to sleep, breathe, exercise normally, and other potential lifetime problems. Nasal blockage can lead to excessive tiredness, lack of energy, and sleeping problems. The decision to have a rhinoplasty usually follows a great deal of time and thought dedicated to undergoing the ...
The rate of longitudinal flow of perilymph has been measured using an ionic tracer technique. Spread of the tracer trimethylphenylammonium (TMPA) along the perilymphatic scalae was monitored with ion-selective microelectrodes following injection of a
Ethacrynic acid belongs to a group of medicines called loop diuretics or "water pills." Ethacrynic acid is given to help treat fluid retention (edema) and swelling that is caused by congestive heart failure, liver disease, kidney disease, or other medical conditions. It works by acting on the kidneys to increase the flow of urine . ...
Neogens Ethacrynic Acid ELISA (Enzyme-Linked ImmunoSorbent Assay) test kit is a qualitative one-step kit designed for use as a screening device for the detection of Ethacrynic acid. The kit was designed for screening purposes and is intended for forensic use only.. ...
Ethacrynic acid is a loop diuretic (water pill) that prevents your body from absorbing too much salt, allowing the salt to instead be passed in your urine.
Cochlea, filled with fluids called perilymph and endolymph, a spiral-shaped cavity in the ear that translates sound waves into electrical nerve impulses and sends them to the cerebral cortex for interpretation. - Stock Image P434/0097
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Thank you so much for sharing this with us.Makes me feel a little less crazy. I have had this over 10 yrs I try to stop counting the years. I am trying to live a thankful life this year and get up every morning trying to count my blessings and stop thinking about how bad I feel all the time. Im constantly on a ship rocking inside and sometimes outside. My last Dr said because of a concussion at age 12 I have Superior Semicircular Canal Dehiscence. She fitted me for prism glasses and wants me to wear sound canceling headphones . Not a great way to live deaf to the world. The glasses dont help without the headphones so I get no relief from this treatment. I also have migraines too . This all started going into menopause nothing before this. Meds make me worse too so I do supplements and watch my diet as best I can. I could ramble on but I just want to thank you so much for this article.I really enjoyed it made me laugh and cry since have a lot of the same feelings that you have. Great to have ...
Define ethacrynic acid. ethacrynic acid synonyms, ethacrynic acid pronunciation, ethacrynic acid translation, English dictionary definition of ethacrynic acid. n. A compound, C13H12Cl2O4, used as a diuretic primarily to treat severe edema. Noun 1. ethacrynic acid - diuretic used to treat edema Edecrin diuretic,...
An in vivo tracer was used to determine if the reticular lamina and/or the cell membranes abutting the endolymphatic space are temporarily disrupted after intense noise exposure (4-kHz OBN, 108-dB SPL, 1.75 h). Using a double-barreled micropipette, the endolymphatic potential (EP) was recorded and artificial endolymph containing 10% carbon particles was injected into the endolymphatic space either
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
ObjectiveTo examine the developmental time course of the mutant phenotype and cellular mechanisms that result in malformations of the superior semicircular cana
TY - JOUR. T1 - Intracellular Potential Changes of Cortis Organ With Anoxia. AU - Nuttall, Alfred L.. AU - Lawrence, Merle. PY - 1979/10. Y1 - 1979/10. N2 - Intracellular measurements of the resting cell membrane potentials of guinea pig Cortis organ were made in order to determine the sensitivity of this cell potential to anoxic hypoxia (a lowered oxygen state due to lack of respiratory oxygen) and to establish differences according to cell types or morphologic regions of the sensory epithelium. The negative cell potentials measured from successful electrode penetrations were found to be relatively more stable and resistant to change during a 120-s period of anoxia than was the positive endocochlear potential. The intracellular resting potentials were also much slower to recover after resumption of respiration. Data obtained from various cells in two different regions of Cortis organ indicate that Cortis organ is receiving oxygen from both the perilymph and the endolymph. An iontophoretic ...
The cochlear stria vascularis produces the positive endocochlear potential (EP) and the endolymph. Both the EP and the endolymph are essential for the physiological function of hair cells. The interme
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered: Allergies- Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully. Children- Appropriate studies have not been performed on the relationship of age to the effects of ethacrynic acid in children below 2 years of age. Safety and efficacy have not been established . Older adults- Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of ethacrynic acid in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may ...
ʿArad: ʿArad, town, southern Israel, in the northeast Negev, named for the biblical Arad, the ruins of which are visible at Tel ʿArad, about 5 12 miles (9 km) east-northeast. The
The cause of Ménières disease is not known. But it may be related to a fluid called endolymph in the inner ear. In people with Ménières disease, too much of this fluid builds up. This creates pressure in the parts of your inner ear that control balance. Experts arent sure why this fluid builds up. It may be that your body produces too much of the fluid. Or maybe the fluid doesnt drain as it should from the inner ear. Or it may be both.. Its hard to predict who will get Ménières disease. But your risk may be higher than normal if you have:. ...
In the anatomy of the human ear, the perilymphatic duct is where the perilymphatic space (vestibule of the ear) is connected to the subarachnoid space. This works as a type of shunt to eliminate excess perilymph fluid from the perilymphatic space around the cochlea of the ear. Perilymph is continuous with cerebrospinal fluid (CSF) in the subarachnoid space. CSF pressure abnormalities do not generally have clinical impact on the inner ear which is explained physically by the bore diameter and length of the perilymphatic duct. This duct goes through the skull and is parallel with but not directly associated with the endolymphatic duct. The duct is lined by an epithelium ...
Purpose: Various studies have revealed that both Fas and its ligand play an important role in cancer biology. The aim of our study was to determine if there is a relationship between the expression of Fas or Fas-ligand in breast cancer and the presence of malignant cells in perilymphatic fat. Material/Methods: Tumor samples from 147 consecutive breast cancer patients, aged 35-81 (median, 59), were subjected to analysis. The expressions of Fas and Fas-ligand were determined immunohistochemically. Results: The expression of Fas, but not Fas-ligand, was significantly less frequent in breast cancer patients in whom malignant cells infiltrated through the perilymphatic fat (p=0.042). The infiltration of paranodal fatty tissue occurred more often in cases of ductal carcinomas (p=0.008), larger primary tumors (pT≥2, p=0.030) and regional lymph node involvement (pN≥1, p=O.021). Univariate analysis revealed that perilymphatic fat infiltration shortened overall survivals in breast cancer ...