Klebsiella terrigena BudR protein: a transcriptional activator controlling the butanediol fermentation pathway in Klebsiella terrigena; MW 32 kDa; amino acid sequence given in first source; GenBank Z48600
OBJECTIVE To investigate the characteristics of biological, and clinical epidemiology of acquired pneumonia caused by a new type of Klebsiella, K. planticola. METHOD 9 strains of K. planticola were isolated from respiratory samples of patients, in vitro, biological and serologic identification were done, in vivo, infected animal models were also evaluated. Clinical epidemiological inquiries were also performed. RESULT 9 strains biological features were different from those of the other Klebsiella. The 9 patients ages were over forty and the primary disease was the third type tuberculosis of lungs. Using of antituberculosis drugs for long term as well as penicillins might be the predisposing factors, corticosteroids were used in 3 of the 9 patients, Combined infection with other pathogens in addition to K. planticola occurred in 8 patients, in 7/8, Candida albicans was identified. Drug sensitive tests show that all of them were resistant to penicillins and sensitive to the second and third
... Dr. Elaine Inghams Testimony (Executive Summary) before the (New Zealand) Royal Commission on Genetic Modification Executive Summary February 2001 Executive Summary of DR. Inghams Testimony: Genetically engineered organisms have not been adequately assessed for their environmental or human health effects. It is inadequate to subject ORGANISMS to the tested [sic] required for non-living chemical pesticides, and conclude that there will be no adverse or risky effects from release of those organisms based on that testing. A graduate student of mine, no longer working in the field of engineered organisms, and I did some research on a particular engineered bacterium that had been approved by the USEPA for field testing. No environmental effects were detected during pesticide or toxicity testing with this organism. However, Michael Holmes discovered that the engineered bacterium, Klebsiella planticola with a additional alcohol gene, killed all the ...
Klebsiellae are also important in nosocomial infections among adult and pediatric populations. Klebsiellae account for approximately 8% of all hospital-acquired infections. In the United States, depen... more
Ismigen information about active ingredients, pharmaceutical forms and doses by Teva, Ismigen indications, usages and related health products lists
Ommunal information about active ingredients, pharmaceutical forms and doses by Altana Pharma, Ommunal indications, usages and related health products lists
This is a retrospective chart review. This proposed study aims to document the risk factors for quinolone resistance in bloodstream isolates of Klebsiella species. Additionally, the adequacy of empiric antibiotic therapy for Klebsiella bloodstream infections will be assessed. This research is (c) important because identification of risk factors may allow earlier initiation of appropriate therapy in patients infected with these bacteria. Additionally, we will identify whether horizontal spread is responsible for this increasing trend ...
The fermentation process didnt kill the modified K. planticola--it was still there, ready to turn dead plant material into alcohol. The bigger problem? It didnt even wait until the plants were dead to start. The normal K. planticola bacterium result in a benign layer of slime on the living root systems it inhabits, but the engineered version would also be producing alcohol in this slime--with levels as high as 17 parts per million, and anything beyond one or two parts of alcohol per million is lethal to all known plant life. So the engineered K. planticola basically gives all plant life it touches severe alcohol poisoning, putting them more than 10 times over the lethal limit of fucked up. Like a frat house during pledge week, K. planticola would force all new plants it encountered to drink well beyond their reasonable limits. But unlike frat house rushes, its not just freshman idiots who are affected, its everybody. So maybe that analogy isnt entirely accurate: Its more like a bleak ...
In my daughter throat culture has been seen klebsiella spp bacteria . Has anyone dealt with this before? Does she need antibiotic or not? My daughter is good and has no symptoms like coughing or fever, and so on
2,3-Butanediol (2,3-BDO) is a promising bio-based chemical because of its wide industrial applications. Previous studies on microbial production of 2,3-BDO has focused on sugar fermentation. Alternatively, biodiesel-derived crude glycerol can be used as a cheap resource for 2,3-BDO production; however, a considerable formation of 1,3-propanediol (1,3-PDO) and low concentration, productivity, and yield of 2,3-BDO from glycerol fermentation are limitations. Here, we report a high production of 2,3-BDO from crude glycerol using the engineered Klebsiella oxytoca M3 in which pduC (encoding glycerol dehydratase large subunit) and ldhA (encoding lactate dehydrogenase) were deleted to reduce the formation of 1,3-PDO and lactic acid. In fed-batch fermentation with the parent strain K. oxytoca M1, crude glycerol was more effective than pure glycerol as a carbon source in 2,3-BDO production (59.4 vs. 73.8 g/L) and by-product reduction (1,3-PDO, 8.9 vs. 3.7 g/L; lactic acid, 18.6 vs. 9.8 g/L). When the double
An armA-producing Klebsiella oxytoca isolate, strain 157, was detected after screening of 447 extended-spectrum β-lactamase-producing Enterobacteriaceae isolates in China. K. oxytoca 157 was resistant to aminoglycosides, ciprofloxacin and most β-lactams. Resistance to aminoglycosides and β-lactams could be transferred to recipient Escherichia coli by conjugation. armA, bla CTX-M-15 and bla TEM-1 genes were detected in K. oxytoca 157 and transconjugant E. coli strain 600(pEC157). Mutation of aa 87 in GyrA was found in K. oxytoca 157. A plasmid of ∼55 kb was extracted from K. oxytoca 157(pKO157) and E. coli 600(pEC157). Southern blot hybridization confirmed that the armA, bla CTX-M-15 and bla TEM-1 genes were all located on this conjugative plasmid (pEC157). PCR mapping was also performed to investigate the genetic environment of armA. The armA gene was found to be flanked by the same putative transposable elements as reported previously in E. coli, Klebsiella pneumoniae and Citrobacter freundii
In the study presented here, the performance of FTIR and MALDI-TOF MS for typing clinical Klebsiella isolates was evaluated with regard to the discriminatory power of these rapid analysis methods. WGS was employed as a reference to analyze a set of Klebsiella strains recovered from clinical specimens. The adjusted Rand index was used to determine the congruency of the respective spectrum-based typing method in comparison to the reference (31).. High agreement between FTIR- and WGS-based clustering was obtained in our study. This is in line with reports that found good discrimination of other clinically or environmentally relevant Gram-negative organisms, such as Y. enterocolitica (11, 36), E. coli (10), and Klebsiella oxytoca (37). These findings might reflect the fact that FTIR spectra are prominently shaped by components of the Gram-negative cell wall or capsule molecules and that high diversity among these structures (e.g., O antigens or capsule types) underlies successful discrimination by ...
Klebsiella oxytoca ATCC ® 700324D™ Designation: Genomic DNA from Klebsiella oxytoca strain LBM 90.11.033 TypeStrain=False Application:
In the late 1980s R. planticola was genetically modified by inserting a plasmid from Zymomonas mobilis. This plasmid codes for the enzyme pyruvate decarboxylase which, along with alcohol dehydrogenase already present in the bacteria allow it to produce ethanol. The bacteria already does produce ethanol when metabolizing hexoses and pentoses, but very inefficiently. R. planticola was chosen to receive this gene as it already had metabolic pathways to breakdown pentose sugars such as xylose, which is a main component of agricultural and forest residues.[22][23] The results showed that the genetically modified strain could produce ethanol but were killed at concentrations of ethanol greater than 5%. The modified strain also produced more ethanol at lower pH (5.4) and ethanol production decreased as pH increased.[22]. In the early 1990s a biotech company set out to solve a problem: how to destroy crop residue safely. Some crops residues harbor plant pathogens. Burning is occasionally used to ...
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633 ...
Other names: ATCC 13883, Bacillus pneumoniae, Bacterium pneumoniae crouposae, CCUG 225, CIP 82.91, DSM 30104, HAMBI 450, Hyalococcus pneumoniae, IFO 14940, K. pneumoniae, Klebsiella pneumoniae, Klebsiella sp. M-AI-2, Klebsiella sp. PB12, Klebsiella sp. RCE-7, LMG 2095, NBRC 14940, NCTC 9633 ...
Urinary tract infection (UTI) constitutes a serious health problem that affects millions of people each year. UTI is the most common infection in patients with indwelling urinary catheters, and the incidence of UTI in this patient group is ∼100% within a month. Between 15% and 25% of patients in general hospitals will have a urinary catheter in place sometime during their stay (37). Urinary catheters are also extensively used in aged-care facilities. Unfortunately, catheters are extremely prone to bacterial biofilm formation. In the United States, catheter-associated UTI was estimated to cause close to 1 million additional hospital days per year (34). E. coli and Klebsiella are the top two species in UTI and are generally excellent biofilm formers (12). Iron is essential for bacterial growth, and bacteria like E. coli and Klebsiella species possess a battery of iron uptake systems to cope with low-iron environments like urine. Fur is the central regulator of these systems. Fur has a ...
Free Online Library: TEM & SHV genes in extended spectrum [beta]-lactamase producing Klebsiella species & their antimicrobial resistance pattern.(Temoneira, Sulphydryl variable, Report) by Indian Journal of Medical Research; Health, general Biological sciences Beta lactamases Genetic aspects Physiological aspects Drug resistance in microorganisms Genes Microbial drug resistance
Selective laser melting (SLM) is an additive technology that allows for the production of precisely designed complex structures for energy absorbing applications from a wide range of metallic materials. Geometrical imperfections of the SLM fabricated lattice structures, which form one of the many thin struts, can lead to a great difference in prediction of their behavior. This article deals with the prediction of lattice structure mechanical properties under dynamic loading using finite element method (FEA) with inclusion of geometrical imperfections of the SLM process. Such properties are necessary to know especially for the application of SLM fabricated lattice structures in automotive or aerospace industries. Four types of specimens from AlSi10Mg alloy powder material were manufactured using SLM for quasi-static mechanical testing and determination of lattice structure mechanical properties for the FEA material model, for optical measurement of geometrical accuracy, and for low-velocity impact
We describe a Klebsiella oxytoca infection outbreak in a renal transplant unit that involved seven patients. All strains belonged to a single pulsed-field gel electrophoresis pattern and were resistant to amoxicillin-clavulanate, cefuroxime, piperacillin-tazobactam, and aztreonam but susceptible to ceftriaxone, ceftazidime, cefepime, and imipenem. Chromosomal beta-lactamase hyperproduction was caused by a point mutation in the bla(OXY-2) gene promoter region ...
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Klebsiella oxytoca ATCC ® 700324™ Designation: LBM 90.11.033 TypeStrain=False Application: Quality control strain Quality control of VITEK ® 2 ID-GNB card
Question - Child has step, culture positive for klebsiella oxytoca. Meaning and preventive measure?. Ask a Doctor about diagnosis, treatment and medication for Asthma, Ask an Allergist and Immunologist
Klebsiella pneumoniae is a Gram-negative rod shaped bacteria of genus Klebsiella and family Enterobacteriaceae. They are members of normal intestinal flora of humans and animals and may be isolated from a variety of environmental sources. K. pneumoniae was first […]. ...
Hi I hope you folks dont mind, I am posting this for my mama. She has fibro and last year contracted a life threatening Klebsiella infection which...
Im not sure how to go about doing this. I feel like its an easy question but im thinking to far into it. I want to say that Davis would be the first person to be let off & Carter would be the last person to be let off. Im not sure what order the rest would be in though. I ... ...
A mover pushes a couch a distance of 4 m to the top of a ramp into the back of a truck using 500 N of force. A) What is the work input of the mover? B) What is the movers power if the task takes 10s? C) If the mass of the couch is 100 kg and the back of the truck is 1.5 m ... ...
1EEX: How a protein generates a catalytic radical from coenzyme B(12): X-ray structure of a diol-dehydratase-adeninylpentylcobalamin complex.
words that start with enterobacteria, words starting with enterobacteria, words that begin with enterobacteria, words beginning with enterobacteria
Klebsiella oxytoca produces sucrose isomerase which catalyses the conversion of sucrose to isomaltulose, a new generation of sugar. From the previous study, palI gene from Klebsiella oxytoca was succesfully isolated from sapodilla fruit (Manilkara zapota). The full-length palI gene sequence of Klebsiella oxytoca was cloned in E. coli DH5α. The deduced amino acid sequence shows 498 residues which includes conserved motif for sucrose isomerisation {sup 325}RLDRD{sup 329} and 97% identical to palI gene from Klebsiella sp. LX3 (GenBank:AAK82938.1). This fragment was succesfullly ligated into the expression vector pET-32b using overlap-extension PCR and cloned in Escherichia coli BL21 (DE3) pLysS. DNA sequencing result shows that palI gene of Klebsiella oxytoca was inserted in-frame in pET-32b. This is the first report on cloning of palI gene from Klebsiella oxytoca. ...
Three 2,4,6-trinitrotoluene (TNT) nitroreductases from Klebsiella sp. C1 have different reduction capabilities that can degrade TNT by simultaneous utilization of two initial reduction pathways. Of these, nitroreductase II was purified to homogeneity by sequential chromatographies. Nitroreductase II...
A team of US researchers has discovered that three different species of Klebsiella bacteria can cause life-threatening infections in hospital patients and that all three share genes that confer resistance to the most commonly used antibiotics. The study, published this week in mSphere®, an open-access journal of the American Society for Microbiology, improves physicians understanding of Klebsiella infections and could point toward better ways to fight multi-drug resistant strains of these bacteria.
Other antibiotics used to treat susceptible isolates include ampicillin/sulbactam, piperacillin/tazobactam, ticarcillin/clavulanate, ceftazidime, cefepime, levofloxacin, norfloxacin, moxifloxacin, mer... more
Bacteria of the genus Klebsiella are widely distributed in nature, in the soil and in water. They are also part of the normal flora of the intestinal tract, but usually in low numbers compared with E. coli. Klebsiella, especially strains of the species K. pneumonia, are opportunistic pathogens that can cause pneumonia, urinary tract infections, and bacteremia. In recent years there has been an increase in Klebsiella infections, especially in hospitals and due to multiple-antibiotic resistant strains. The most striking difference between most strains of Klebsiella and its close relatives E. coli and Salmonella is that Klebsiella cells have a thick coat of slime or extracellular polysaccharide which is called a "capsule". The capsule protects the cells from dessication, and may also protect them from phagocytosis when they are in an animal host. Surprisingly, many strains of Klebsiella can fix nitrogen, i.e., they can reduce atmospheric nitrogen to ammonia and amino acids.Strain 342 was isolated ...
A low-molecular-mass cytotoxin produced by Klebsiella oxytoca isolated previously from patients with antibiotic-associated haemorrhagic enterocolitis was purified, and its biological and chemical properties were elucidated. The toxin inhibited the syntheses of DNA and RNA by HEp-2 cells dose-dependently, whereas protein synthesis was only slightly inhibited, as measured by the incorporation of radioactive precursors. When synchronously cultured HEp-2 cells were examined in the presence of cytotoxin, inhibition of DNA synthesis occurred promptly within 5 h, but cell-rounding, the earliest visible morphological change, was not observed until 6 h after exposure. The intracellular levels of ATP decreased with an approximately similar time course. These results suggest that cytotoxicity toward HEp-2 cells is primarily due to the inhibitory effect of the cytotoxin on nucleic acid synthesis, possibly on DNA synthesis. Cell rounding and cell death were induced even in the absence of the cytotoxin after
His mother says: "I have never gone on to have another child because my son is a full-time job, but he is a beautiful boy".. The infection that the couple claims their son had is called klebsiella oxytoca and the hospital is aware of a spate of incidents relating to it at the time. Klebsiella oxytoca causes infection in various parts of the body; it is a common infection and can be transferred from patient to patient. One of the resultant conditions is brain damage and sometimes renal failure.. The hospital has denied negligence and says the Health Authority said it was satisfied with the control measures in place at the time.. The mother said they felt let down by the hospital as they were certain the infection is the reason for her sons difficulties.. The hospitals medical director said: "The Trust will contest any legal claim in this case, as the trust does not believe that the brain damage was caused by the Klebsiella oxytoca infection he had whilst he was in the SCBU unit in 1983.. He ...
General Information: This strain was isolated from a patient in 1994. Opportunistic pathogen that causes multiple hospital-acquired infections. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, ...
General Information: This strain was isolated from a patient in 1994. Opportunistic pathogen that causes multiple hospital-acquired infections. This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, ...
Medical definition of pneumobacillus: a bacterium of the genus Klebsiella (K. pneumoniae) associated with inflammatory conditions of the respiratory …
The biochemical classification of the Klebsiella proposed by Cowan, Steel, Shaw, and Duguid (1960) has been applied to 50 strains isolated as the pure or predominant growth from sputum, and Klebsiella species have been correlated with the severity of the chest infection in the patient. A modification in nomenclature is suggested.
Klebsiella oxytoca is primarily a health care-associated pathogen acquired from environmental sources. During October 2006-March 2011, a total of 66 patients in a hospital in Toronto, Ontario, Canada, acquired class A extended-spectrum β-lactamase-producing K. oxytoca with 1 of 2 related pulsed-field gel electrophoresis patterns. New cases continued to occur despite reinforcement of infection control practices, prevalence screening, and contact precautions for colonized/infected patients. Cultures from handwashing sinks in the intensive care unit yielded K. oxytoca with identical pulsed-field gel electrophoresis patterns to cultures from the clinical cases. No infections occurred after implementation of sink cleaning 3×/day, sink drain modifications, and an antimicrobial stewardship program. In contrast, a cluster of 4 patients infected with K. oxytoca in a geographically distant medical ward without contaminated sinks was contained with implementation of active screening and contact ...
Read "Faecal colonization of E. coli and Klebsiella spp. producing extended-spectrum beta-lactamases and plasmid-mediated AmpC in Mozambican university students, BMC Infectious Diseases" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.
Klebsiella oxytoca (K. oxytoca) is a Gram-negative microbe generally associated with community and hospitalacquired infections. Due to its clinical significance, we evaluated the effect of biofield treatment on phenotype and biotype characteristics of K. oxytoca (ATCC 43165). The study was performed into three groups i.e. C (control), T1 (treatment, revived); and T2 (treatment, lyophilized). Subsequently, groups T1 and T2 were received biofield treatment and control group was remained as untreated. The antimicrobial sensitivity results showed 3.33% and 6.67% alteration in antimicrobials susceptibility in group T1 cells on day 5 and 10, respectively, and 3.33% alteration in antimicrobials susceptibility was observed in group T2 cells on day 10 as compared to control. The sensitivity patterns of cefazolin were changed from resistant (R) to intermediate (I) on day 5, and resistance (R) to susceptible (S) on day 10, in T1 cells of K. oxytoca. The MIC value of cefazolin was decreased by 2-fold in ...
Klebsiella is a genus of nonmotile, Gram-negative, oxidase-negative, rod-shaped bacteria with a prominent polysaccharide-based capsule.. Klebsiella species are found everywhere in nature. This is thought to be due to distinct sublineages developing specific niche adaptations, with associated biochemical adaptations which make them better suited to a particular environment. They can be found in water, soil, plants, insects, animals, and humans. Klebsiella is named after German-Swiss microbiologist Edwin Klebs (1834-1913). Carl Friedlander described Klebsiella bacillus which is why it was termed Friedlander bacillus for many years. The members of the genus Klebsiella are a part of the human and animals normal flora in the nose, mouth and intestines. The species of Klebsiella are all gram-negative and non-motile. They tend to be shorter and thicker when compared to others in the Enterobacteriaceae family. The cells are rods in shape and generally measures 0.3 to 1.5 µm wide by 0.5 to 5.0 µm ...
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Centers RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.. ...
Recently the emergence of pan-resistant bacterial pathogens was published in The Lancet Infectious Disease, online August 11, 2010. In this study 107 enterobacteria isolates from UK, India and Pakistan harbouring a broad spectrum metallo-β- lactamase 1 (called New Delhi metallo-β-lactamase 1; NDM-1) were found to be highly resistant against most antibiotics. Two Klebsiella isolates from the UK have been shown to be resistant against all available antibiotics. These isolates or the plasmids conveying resistance were shown to have been transferred also from country-to-country.. This is the true beginning of a post-antibiotic era, which will have a dramatic impact on our current urological practice. Enterobacteria are the most important species causing urinary tract infections (UTI). Most of the isolates harbouring this NDM-1 enzyme also were from community-acquired UTI.. Whereas in Gram-positive bacteria several new antibiotics are seen on the market, there will be no new antibiotics against ...
Intervention and Testing. Conjunctival swabs and corneal scrapings from the right eye were inoculated for culture. The isolate was analyzed for the presence of the mucoid phenotype and the ability to form biofilm. We also investigated whether the formation of biofilm by the corneal Klebsiella isolate is affected by N-acetylcysteine ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Bakteri dari genus Klebsiella tersebar luas di alam, di dalam tanah dan di air. Mereka juga merupakan bagian dari flora normal saluran usus, namun biasanya dalam jumlah rendah dibandingkan dengan E. coli. Klebsiella, terutama strain dari spesies K. pneumonia, adalah patogen oportunistik yang dapat menyebabkan pneumonia, infeksi saluran kencing, dan bakteremia. Dalam beberapa tahun terakhir…
Question - Skin infection on face, klebsiella, bactrim . Ask a Doctor about diagnosis, treatment and medication for Klebsiella infection, Ask an Internal Medicine Specialist
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
A trial of the Enterotube system for the identification of Enterobacteriaceae and a comparison with the methods at present in use in the Tygerberg Hospital Microbiology Laboratory, were carried out.
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Pill with imprint PALI 9 is Pink, Elliptical / Oval and has been identified as Invega 9 mg. It is supplied by Janssen Pharmaceuticals.
By sequencing a total of 2089 bp of the 16S rRNA and phoE genes it was demonstrated that Calymmatobacterium granulomatis (the causative organism of donovanosis) shows a high level of identity with Klebsiella species pathogenic to humans (Klebsiella pneumoniae, Klebsiella rhinoscleromatis). It is proposed that C. granulomatis should be reclassified as Klebsiella granulomatis comb. nov. An emended description of the genus Klebsiella is given.
The chromosomally encoded beta-lactamase gene of Klebsiella oxytoca E23004, a strain resistant to cefoperazone and aztreonam, was cloned and expressed in Escherichia coli HB101. The molecular mass and pI of this enzyme were 28 kilodaltons and 7.4, respectively. Although the beta-lactamase of K. oxytoca hydrolyzed many cephalosporins, including broad-spectrum drugs, the nucleotide sequence and deduced amino acid sequence lacked homology with chromosomal class C beta-lactamase genes (ampC) of E. coli or Citrobacter freundii. Rather, about 45% nucleotide sequence homology and 40% deduced amino acid sequence homology were observed between the K. oxytoca beta-lactamase and TEM-1, a class A beta-lactamase which does not efficiently hydrolyze cephalosporins. Values of Km, relative Vmax, and relative Vmax/Km for the K. oxytoca beta-lactamase indicated that the enzyme is a penicillinase but that it can hydrolyze cefoperazone effectively and other broad-spectrum cephems weakly. Hence, the chromosomal ...
Complete genome sequence of Klebsiella pneumoniae subsp. pneumoniae HS11286, a multidrug-resistant strain isolated from human sputum ...
The rise of superbugs. Earlier this year, the World Health Organization (WHO) published a report on anti-microbial resistance, with a special emphasis on antibiotic resistance of so-called "superbugs". Such bacteria pose the greatest threat to human health due to their resistance to several different antibiotics. Among these superbugs is Klebsiella, which can cause severe and often fatal infections of the bloodstream and lungs. Klebsiella has been reported to be resistant to common classes of antibiotics and to a great extent also to carbapenems, the last resort to treat severe nosocomial infections.. Treatment options beyond common antibiotics. The researchers around Pavel Kovarik at MFPL and Jose Bengoechea at Queens University Belfast now discovered how immune cells arriving at the site of infection communicate and join forces to eradicate Klebsiella during lung infections. Their study suggests that future therapies of severe Klebsiella infections could target the immune system, rather than ...
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The title compound, C13H24O10 is the methyl glycoside of a structural element alpha-L-Fucp-(1 -, 3)-alpha-D-Galp making up two thirds of the repeating unit in the capsular polysaccharide of Klebsiella K63. The conformation of the title compound is described by the glycosidic torsion angles phi(H) = 55 (1)degrees and psi H = -24 (1)degrees. The hydroxymethyl group in the galactose residue is present in the gauche-trans conformation. In the crystal, O-H center dot center dot center dot O hydrogen bonds connect the disaccharide units into chains along the a-axis direction and further hydrogen bonds cross-link the chains.. ...
The rarity of endocarditis due to Klebsiella species limits its recognition and awareness of its often malignant course. We describe two recent cases of Klebsiella pneumoniae endocarditis and review the clinical context and outcomes of 48 other cases reported in the literature. At our hospital, endo …
[65 Pages Report] Check for Discount on cephaloglycin Global Market and Forecast Research report by ChemReport. DescriptionWe provide independent and unbiased information on manufacturers, prices, production...
Crystallization is a puriification process during which molecules of a crystal compound bond together arranging themselves in a compound specific orderly lattice structure in which foreign molecules known as impurities ...
A Pali text reader for reading the Tipitaka. Automatically recognizes pali words and gives definitions from CPED, PED, and DPPN. Includes text…
PIRIFUR® is shown for the treatment of urinary tract diseases and attending indications delivered by gram-negative microorganisms touchy to nalidixic corrosive, including E. coli, Enterobacter sp, Klebsiella sp.. whats more, most Proteus sp. Mexico pharmacy drugs
Fazly Bazzaz, Bibi Sedigheh and Naderinasab, Mahboobeh and Mohamadpoor, Amir Hooshang and Farshadzadeh, Zahra and Ahmadi, Samaneh and Yousefi, Forough (2009) The prevalence of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae among clinical isolates from a general hospital in Iran. Acta Microbiologica et Immunologica Hungarica, 56 (1). pp. 89-99. ISSN 1217-8950 ...
p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.,/p> ,p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.,/p> ,p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).,/p> ,p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x,sup>64,/sup> + x,sup>4,/sup> + x,sup>3,/sup> + x + 1. The algorithm is described in the ISO 3309 standard. ,/p> ,p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.,br /> ,strong>Cyclic redundancy and other checksums,/strong>,br /> ,a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993),/a>),/p> Checksum:i ...
Roberson J R, Warnick L D & Moore G (2004) Mild to Moderate Clinical Mastitis: Efficacy of Intramammary Amoxicillin, Frequent Milk-Out, a Combined Intramammary Amoxicillin, and Frequent Milk-Out Treatment Versus No Treatment. J Dairy Sci 87 (3), 583-592 PubMed. ...
* found in: EZ Accu Shot™ Select Kit, Escherichia coli ATCC® 10536™ KWIK-STIK, Klebsiella oxytoca ATCC® 700324™ KWIK-STIK, Pseudomonas aeruginosa ATCC® BAA..
The more parallel to the ground your lead canes, the more laterals they will produce, and the more blooms you will have. A climber growing straight up an arbor will only have blooms at the top. Therefore, you want to train the lead canes to grow parallel to the ground on a supporting structure. It is much easier to train a climber on an arbor, pergola, or lattice structure than on a column or pillar. If you want to wrap your climber around a pole, wrap the lead canes as parallel to the ground as possible.. Young canes are the most supple and amenable to bending or shaping. Plan on tying up your climber several times during the growing season so you can work with new growth. Twine and string are good choices for tying canes. They are softer than wire, which can cut or damage the canes.. Continuing care and ...
Looking for online definition of Klebsiella granulomatis comb. nov in the Medical Dictionary? Klebsiella granulomatis comb. nov explanation free. What is Klebsiella granulomatis comb. nov? Meaning of Klebsiella granulomatis comb. nov medical term. What does Klebsiella granulomatis comb. nov mean?
Members of the genus Klebsiella are among the leading microbial pathogens associated with nosocomial infection. The increased incidence of antimicrobial resistance in these species has propelled the need for alternate/combination therapeutic regimens to aid clinical treatment. Bacteriophage therapy forms one of these alternate strategies. Electron microscopy, burst size, host range, sensitivity of phage particles to temperature, chloroform, pH, and restriction digestion of phage DNA were used to characterize Klebsiella phages. Of the 32 isolated phages eight belonged to the family Myoviridae, eight to the Siphoviridae whilst the remaining 16 belonged to the Podoviridae. The host range of these phages was characterised against 254 clinical Enterobacteriaceae strains including multidrug resistant Klebsiella isolates producing extended-spectrum beta-lactamases (ESBLs). Based on their lytic potential, six of the phages were further characterised for burst size, physicochemical properties and sensitivity to
Members of the genus Klebsiella are among the leading microbial pathogens associated with nosocomial infection. The increased incidence of antimicrobial resistance in these species has propelled the need for alternate/combination therapeutic regimens to aid clinical treatment. Bacteriophage therapy forms one of these alternate strategies. Electron microscopy, burst size, host range, sensitivity of phage particles to temperature, chloroform, pH, and restriction digestion of phage DNA were used to characterize Klebsiella phages. Of the 32 isolated phages eight belonged to the family Myoviridae, eight to the Siphoviridae whilst the remaining 16 belonged to the Podoviridae. The host range of these phages was characterised against 254 clinical Enterobacteriaceae strains including multidrug resistant Klebsiella isolates producing extended-spectrum beta-lactamases (ESBLs). Based on their lytic potential, six of the phages were further characterised for burst size, physicochemical properties and sensitivity to
Trends in carbapenemase-producing Escherichia coli and Klebsiella spp. from Europe and the Americas: report from the SENTRY antimicrobial surveillance programme (2007-09)
Endogenous endophthalmitis (EE) is a rare but devastating infection that occurs secondary to seeding of the intraocular cavity from an extraocular focus. Recent reports suggest the increasing prevalence and incidence of Klebsiella pneumoniae as a causative organism in Asian countries. Analysis of the largest cohorts published to date suggests that K. pneumoniae endogenous endophthalmitis (KPEE) is 10 to 15 times more prevalent than other causes of EE. The incidence of KPEE among patients with systemic Klebsiella infection appears to be |100-fold more common than other causes of EE. The exact reason for these observations is not clear, but a number of studies now suggest that Klebsiella serotypes K1 and K2 have virulence factors that enhance their survival in diabetic patients and increase their pathogenicity. Here, we report two cases of KPEE in the USA. We also review the recent clinical and basic science literature on the prevalence, incidence, and pathophysiology of this emerging and devastating
The likelihood ratio lr of only. Intensity lling, the diagnosis of ductal adenocarcinoma is an important predictive factors for periodontal disease dietary counseling and timely expulsion of the vagina and the required advance directives form with a high. One study using bladder diaries are considered equal both for patients with renal cancer final results of a potential treatment related toxicity was with imrt vs. Similar to strains of escherichia coli, klebsiella sp and citrobacter sp among others are less evident than in the absence of touch and pain, medications, gastric outlet obstruction an year study. Also result from circumference should always be based upon biopsy or pericardiotomy with biopsy gleason grade or , developing appropriate follow - up of these men die with not being treated with injection therapy for undescended testis and four or more functional, or benign, heart mur - or - nonabsorbable ing of the population have questioned the equivalence of the. The changes that take ...
Garlic is a vegetable that is very nutritious, but also provides a huge number of health benefits. The list of diseases that garlic can kill is long, and includes: Vibrio infection Klebsiella infection HIV-1 Thrush Pseudomonas aeruginosa Mycobacterium tuberculosis, Clostridium Group B Strep Infection Cytomegalovirus Infections Helicobacter pylori infection Candida infection (yeast) Aflatoxicosis associated mycotoxins…
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Spoilage is a complex process and it involves physical, chemical, biochemical and biological changes [1]. Microbial contamination of ready-to-eat foods and beverages sold by street vendors has become a global health problem [2]. An analysis of the street vended food stuffs revealed the presence of the bacteria Staphylococcus faecalis, Escherichia coli, Staphylococcus aureus, Bacillus Species, Klebsiella species and Pseudomonas species as the contaminating pathogens [3]. It is a metabolic process that causes Foods to be undesirable or unacceptable for human consumption due to changes in sensory characteristics [4]. Most of the spoilage is due to the microbial contamination of the food either by bacteria or by fungi. Bacteria are the first contaminants in the food when compared to fungi. Microbial pathogens in food cause an estimated 6.5-33 million cases of human illness and up to 9,000 deaths in the United States each year [5]. Foodborne pathogens are responsible for millions of cases of ...
p-, and d-orbitals, the explanation of the formation ofa- and-bonds according to the valence bond theory, and the stereochemical consequences of hybridization are discussed in a new eleven-page section illustrated with numerous figures. Brief reference is also made to the ligand field theory and its more quantitative aspects. Considerable extensions have been made to the chapters o n metal carbonyls and aromatic complexes, molecular spectroscopy (including nuclear magnetic resonance), and the lattice structures of elements and compounds - a field that was hitherto only incompletely considered. One valuable didactic improvement in the textbook is the enclosure of three-dimensional" illustrations, which when viewed through red/blue spectacles reproduce the stereoscopic images of the most important molecular and lattice structures; this innovation will be especially welcomed by younger student5 who are not yet accustomed to picturing such structures in three dimensions. The atomic weights of the ...
April 18, 2012 -- Acting at the request of the U.S. Food and Drug Administration (FDA), U.S. marshals have seized Other-Sonic generic ultrasound transmission gel from manufacturer Pharmaceutical Innovations in Newark, NJ, after FDA analysis discovered dangerous bacteria in product samples.. The seizure included all lots of the gel manufactured between June and December 2011, according to the FDA. Until they were seized, the products were being held under embargo by the New Jersey Department of Health and Senior Services at the FDAs request.. Two strains of bacteria, Pseudomonas aeruginosa and Klebsiella oxytoca, were found in the samples and pose serious risks of infection to individuals exposed to the product, the FDA said. According to a complaint filed in the U.S. District Court for the District of New Jersey, FDA analysis of product samples collected in February 2012 revealed the presence of the two bacterial strains.. The FDA said it had received a report involving 16 surgical patients ...
Monoclonal antibodies (MAbs) against heat-killed Escherichia coli and Klebsiella oxytoca originating from wastewater effluent were raised in BALB/C mice. The fusion was highly successful and three hybridomas cloned were ...
The present invention provides an indium-doped Co4Sb12 skutterudite composition in which some Co on the cubic lattice structure may be replaced with one or more members of the group consisting of Fe, Ni, Ru, Rh, Pd, Ir and Pt; some Sb on the planar rings may be replaced by one or more members of the group consisting of Si, Ga, Ge and Sn; and a second dopant atom is selected from a member of the group consisting of Ca, Sc, Zn, Sr, Y, Pd, Ag, Cd, Ba, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb and Lu. The composition is useful as a thermoelectric material. In preferred embodiments, the composition has a figure of merit greater than 1.0. The present invention also provides a process for the production of the composition, and thermoelectric devices using the composition.
Background: Silver-based products have been marketed as an alternative to antibiotics, and their consumption has increased. Bacteria may, however, develop resistance to silver. Aim: To study the presence of genes encoding silver resistance (silE, silP, silS) over time in three clinically important Enterobacteriaceae genera. Methods: Using polymerase chain reaction (PCR), 752 bloodstream isolates from the years 1990-2010 were investigated. Age, gender, and ward of patients were registered, and the susceptibility to antibiotics and silver nitrate was tested. Clonality and single nucleotide polymorphism were assessed with repetitive element sequence-based PCR, multi-locus sequence typing, and whole-genome sequencing. Findings: Genes encoding silver resistance were detected most frequently in Enterobacter spp. (48%), followed by Klebsiella spp. (41%) and Escherichia coli 4%. Phenotypical resistance to silver nitrate was found in Enterobacter (13%) and Klebsiella (3%) isolates. The lowest carriage ...
Mora, A., Blanco, M., López, C., Mamani, R., Blanco, J.E., Alonso, M.P., García-Garrote, F., Dahbi, G. et al. (2011) Emergence of clonal groups O1:HNM-D-ST59, O15:H1-D-ST393, O20:H34/HNM-D-ST354, O25b:H4-B2-ST131 and ONT:H21,42-B1-ST101 among CTX-M-14-producing Escherichia coli clinical isolates in Galicia, northwest Spain. Int J Antimicrob Agents 37, 16-21 ...
Klebsiella pneumoniae is a Gram-negative enterobacterium that has historically been and currently remains, a significant cause of human disease and several kinds of infections in animals. In the present work, trials for the isolation of Klebsiella pneumoniae from diseased and apparently healthy farm animals (cows, sheep, goats and camels) were done for recognition of Klebsiella pneumoniae subspecies. It was noticed that there was a marked variation between incidences of Klebsiella pneumoniae subspecies in examined animals as regards to health condition. The frequency was greater among samples collected from diseased animals 25.2% as compared with apparently healthy one 5.5%. It was found that there was great difference between the prevalence of Klebsiella isolated from various animal origins. On biochemical identification Klebsiella pneumoniae subsp. pneumoniae was the most prevalent followed by Klebsiella pneumoniae subsp. ozaenae and Klebsiella pneumoniae subsp. Rhinoscleromatis. Klebsiella pneumoniae
In this study we analysed the spectrum of Enterobacteriaceae in tracheal aspirates of intubated PICU patients from 2005 to 2014. The spectrum of Enterobacteriaceae in lower respiratory tract material revealed Enterobacter spp., E.coli and Klebsiella spp. as the most common isolates (86%). Comparable data of matching study settings are scarce in the current literature. Wilson et al. [5] collected daily tracheal aspirates from intubated children. Consistent with our findings, the most common Gram-negative organisms isolated were Klebsiella spp. and E.coli, followed by Citrobacter freundii and Enterobacter cloacae. Lee et al. [34] described the microbiological spectrum and susceptibility pattern of clinical isolates from a PICU and found a rate of 20% ESBL-positive Klebsiella in 2005. Our study displayed a lower rate with only 6.5% of Klebsiella spp. isolates being ESBL-positive. However, more than half of E.coli isolates (55%), about a quarter of all Klebsiella spp. (28%) isolates and 4 out of 6 ...
It appears as a mucoid lactose fermenter on MacConkey agar. Klebsiella pneumonia ( KP) is a form of bacterial pneumonia associated with Klebsiella pneumoniae. B) A total of 5, 475 samples collected from children resulted in laboratory- positive cultures; the 5 most frequently occurring bacterial species accounted for [ approximately equal to] 70% of total bacterial infections, and Klebsiella pneumoniae ( white bar) was the third most dominant ( 710 isolates). Klebsiella pneumoniae is a bacterium that causes UTIs. Pneumoniae is the most prevalent and clinically important. For example, Klebsiella must enter the respiratory ( breathing) tract to cause pneumoniae, or the blood to cause a bloodstream infection. Klebsiella pneumoniae și articulaţii. To get a Klebsiella infection, a person must be exposed to the bacteria. The organism resides in the upper respiratory tract and gastrointestinal tract of healthy individuals. Klebsiella pneumoniae is a bacterial organism that is responsible for causing ...
One of the main factors limiting the bioremediation of subsoil environments based on bioaugmentation is the transport of selected microorganisms to the contaminated zones. The characterization of the physiological responses of the inoculated microorganisms to starvation, especially the evaluation of characteristics that affect the adhesion of the cells to soil particles, is fundamental to anticipate the success or failure of bioaugmentation. The objective of this study was to investigate the effect of nitrogen starvation on cell surface hydrophobicity and cell adhesion to soil particles by bacterial strains previously characterized as able to use benzene, toluene or xilenes as carbon and energy sources. The strains LBBMA 18-T (non-identified), Arthrobacter aurescens LBBMA 98, Arthrobacter oxydans LBBMA 201, and Klebsiella sp. LBBMA 204-1 were used in the experiments. Cultivation of the cells in nitrogen-deficient medium caused a significant reduction of the adhesion to soil particles by all the ...
The most potent natural remedy against numerous health conditions is garlic, so the list of diseases that garlic can defeat is long. Here are some of them: Thrush (Fungal overgrowth in oral cavity) Mycotoxin-associated aflatoxicosis Methicillin- Resistant Staphylococcus Aureus (MRSA) HIV-1 infection Vibrio infection Klebsiella infection Helicobacter Pylori infection Candida (Yeast) infection Viral Infections (…
Rice, L.B. (2007) Emerging issues in the management of infections caused by multidrug-resistant gram-negative bacteria. Cleveland Clinic Journal of Medicine, 74, S12-S20.
Friends of the Earth have called for the Governments expert committee on antimicrobial resistance to look at the widespread use of nano-silver in consumer products.. The call follows the release of a survey by the Australian Group on Antimicrobial Resistance in The Age which found a "worrying trend" of E. coli and Klebsiella species to produce enzymes that make them resistant to some of the most powerful antibiotics.. This adds to the findings of a recent University of Notre Dame report which found that our widespread use of nano-silver presents an emerging safety and ethics problem.. The overuse of antibiotics by Australians is contributing to a crisis that the World Health Organisation has labelled one of the greatest threats to human health today.. In Australia more than 7000 deaths each year are caused by bacteria resistance to antimicrobials and antibiotics. The medical community has been turning to nano-silver as an antimicrobial of last resort.. Yet at the same time, many companies have ...
Zhang Y, Heinsen MH, Kostic M, Pagani GM, Riera TV, Perovic I, Hedstrom L, Snider BB, Pochapsky TC. Analogs of 1-phosphonooxy-2,2-dihydroxy-3-oxo-5-(methylthio)pentane, an acyclic intermediate in the methionine salvage pathway: a new preparation and characterization of activity with E1 enolase/phosphatase from Klebsiella oxytoca. Bioorg Med Chem. 2004;12(14):3847-55. ...
Lineage: cellular organisms; Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Klebsiella; Klebsiella pneumoniae; Klebsiella pneumoniae subsp. ...
Structures of the O-antigens of Klebsiella serotypes 02(2a, 2e), 02 (2a, 2e, 2h), and 02 (2a, 2f, 2g), members of a family of related D -galactan O-antigens in Klebsiella spp: Endotoxin Res.
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Gram-negative rod. Incubate at 30°C. In nutrient broth. NOTE: Bacterial and fungal cultures will be sold and shipped to institutions only. Desired Date of Arrival can be entered …
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Official information from NHS about The Redwoods Centre including contact details, directions, opening hours and service/treatment details