TY - JOUR. T1 - Effects of ambient and stagnant hypoxia on the mechanical and electrical activity of the canine upper jejunum. AU - Meissner, A.. AU - Bowes, K. L.. AU - Sarna, S. K.. PY - 1976. Y1 - 1976. N2 - The effects of ambient and stagnant hypoxia on the mechanical and electrical activity of the upper jejunum were studied in 32 anesthetized dogs. A 50 or 75% reduction in oxygen content of inhaled air produced ambient hypoxia; superior mesenteric artery (SMA) occlusion or thrombin induced mesenteric thrombosis resulted in stagnant hypoxia. Induction of hypoxia was immediately followed by a transient increase in mechanical activity. A 50% reduction in oxygen content had no other effect. A 75% reduction in oxygen content resulted in a gradual decrease in electrical control activity (ECA) frequency and in the disappearance of electrical response activity (ERA), and in jejunal contractions; however, ECA persisted until cardiac arrest occurred after 30 to 45 minutes of hypoxia. Occlusion of the ...
Partially digested food, known as chyme, enters the jejunum from the duodenum. As chyme enters the jejunum, it is mixed by segmentations, or localized smooth muscle contractions in the walls of the jejunum. These segmentations help to circulate chyme and increase its contact with the walls of the jejunum. The walls of the jejunum are folded many times over to increase its surface area and allow it to absorb nutrients. Each epithelial cell on the surface of the jejunum contains microscopic folds of cell membrane called microvilli that create tiny pockets and increase the contact between the cells and chyme. The entire wall of the jejunum is also folded into microscopic finger-like ridges known as villi that form larger pockets and further increase the surface area of the jejunum. At the macroscopic level, the inner surface of the jejunum contains many wrinkles of tissue known as circular folds, which create even more pockets for chyme and further increase the surface area available for ...
TY - JOUR. T1 - Enterooxyntin release from isolated perfused canine jejunum. AU - Walker, W. A.. AU - Strodel, W. E.. AU - Eckhauser, F. E.. AU - Heldsinger, A.. AU - Vinik, A. I.. PY - 1983/5. Y1 - 1983/5. N2 - A humoral factor may mediate the intestinal phase of gastric acid secretion. An ex vivo perfused segment of canine jejunum maintained by an oxygenated asanguinous physiologic perfusate was used to test for release of an enterooxyntin (EO) in response to balloon distention at 30 mm Hg for 15 min. Gastric acid secretion in guinea pig fundic mucosa was determined indirectly by a quantitative cytochemical bioassay (CBA) of oxyntic cell hydroxyl ion production (HIP). An increase in the optical density (OD) caused by the cytochemical stain in the oxyntic cells reflects HIP, an index of acid secretion. Basal OD for segments with distention was 16.6 ± 0.53 and for those without 15.5 ± 0.68 (NS). Results are expressed as mean change of OD from basal (mean ΔOD ± SEM). {A table is presented}. ...
The middle portion of the small intestine is referred to as the jejunum. It connects the duodenum to the ileum. The length of the jejunum is approximately 2.5m. The pH of the jejunum is maintained between 7 and 9, i.e., either neutral or slightly alkaline. The internal membrane of the jejunum is lined with finger like projections referred to as the villi. The surface area of the internal membrane of the jejunum that is available for the absorption of nutrients and products of digestion is increased manifold by the presence of villi. The epithelial cells lining the villi have microvilli. Various nutrients are transported through the epithelial cells of the jejunum. The sugar fructose moves through passive transport and the amino acids, vitamins, small peptides and glucose moves through active transport. The wall of the jejunum contains longitudinal and circular smooth muscles that help to move the food further in the jejunum by a process referred to as peristalsis.
TY - JOUR. T1 - Effect of 1,25-(OH)2D3 on jejunal absorption of magnesium in patients with chronic renal disease. AU - Schmulen, A. C.. AU - Lerman, M.. AU - Pak, C. Y C. PY - 1980/1/1. Y1 - 1980/1/1. N2 - These studies were performed to see if jejunal malabsorption of magnesium in patients with chronic renal disease was influenced by therapy with 1α,25-dihydroxyvitamin D3 [1,25-(OH)2D3; 2 μg/day by mouth for 7 days]. This treatment restored normal serum concentrations of the vitamin D metabolite from 0.9 ± 0.2 to 4.2 ± 0.6 ng/dl. Jejunal absorption of magnesium, measured by a triple-lumen constant-perfusion technique, was enhanced in each of the seven patients by this therapy. The mean value rose from 0.04 ± 0.02 to 0.13 ± 0.02 mmol.30 cm-1.h-1. This last value is similar to the magnesium absorption rate in untreated normal subjects. These results demonstrate that magnesium absorption in the human jejunum is dependent on vitamin D, and they show that 1α,25-dihydroxyvitamin D3 therapy in ...
BACKGROUND: L-Arginine has been shown to induce fluid secretion in human jejunum. Nitric oxide, a derivative of L-arginine is thought to have an important role as an intestinal secretagogue. AIM: To determine the effect of L-arginine and the nitric oxide synthase inhibitor, nitro L-arginine methyl ester (L-NAME), on fluid and electrolyte movement in rat jejunum. METHODS: A 25 cm segment of rat jejunum was perfused in situ with iso-osmotic solutions containing either (1) saline, (2) D-arginine 20, (3) L-arginine 20, (4) L-NAME 0.1, 1, or 20 mmol/l, or (5) a combination of L-arginine 20 and L-NAME 0.1, 1, or 20 mmol/l. In further groups the effect of a subcutaneous injection of L-NAME 100 mg/kg was examined in rats pretreated with either D-or L-arginine 500 mg/kg. RESULTS: L-Arginine, unlike D-arginine, induced fluid secretion despite being better absorbed (mean -7.3 v 17.0 microliters/min/g; p , 0.01). L-NAME at 0.1 mmol/l had no effect on basal fluid movement but reversed L-arginine induced ...
The jejunum (/dʒɪˈdʒuːnəm/) is the second part of the small intestine in humans and most higher vertebrates, including mammals, reptiles, and birds. The jejunum lies between the duodenum and the ileum. The jejunum is considered to begin at the attachment of the suspensory muscle of the duodenum to the duodenum, a location called the duodenojejunal flexure. The division between the jejunum and ileum is not anatomically distinct. In adult humans, the small intestine is usually 6-7m long, about two-fifths of which (2.5 m) is the jejunum. The interior surface of the jejunum-which is exposed to ingested food-is covered in finger-like projections of mucosa, called villi, which increase the surface area of tissue available to absorb nutrients from ingested foodstuffs. The epithelial cells which line these villi have microvilli. The transport of nutrients across epithelial cells through the jejunum and ileum includes the passive transport of sugar fructose and the active transport of amino acids, ...
A morphometric and immunohistochemical restudy was made of jejunal biopsy specimens from 5 patients with soy allergy and the results obtained were compared to those from specimens taken before soy feeding and to those at a later time. All the patients had had previous cows milk allergy with malabsorption. Gastrointestinal symptoms presented within two weeks of starting the soy based formula but in two patients the symptoms were mild and these patients were able to continue soy feeding. Jejunal biopsy specimens taken within 3 days from the reaction to soy showed villous atrophy associated with crypt hyperplasia and an increased cell renewal rate. Also, these specimens showed an inflammatory reaction in the lamina propria and in the epithelium, and the numbers of IgA- and IgM-containing cells were increased. Later, when the soy proteins were eliminated, the morphology of the jejunum improved and the cell numbers were reduced to normal. The intestinal damage and the local immune reaction caused by soy
TY - JOUR. T1 - Effect of E. coli STa enterotoxin on mucosal surface pH of pig proximal jejunum in vivo. AU - McEwan, G T. AU - Schousboe, B. AU - Skadhauge, E. PY - 1989. Y1 - 1989. KW - Animals. KW - Animals, Suckling. KW - Bacterial Toxins. KW - Enterotoxins. KW - Escherichia coli Proteins. KW - Hydrogen-Ion Concentration. KW - Intestinal Mucosa. KW - Jejunum. KW - Swine. M3 - Article. VL - 86. SP - 186. EP - 188. JO - Acta veterinaria Scandinavica. Supplementum. JF - Acta veterinaria Scandinavica. Supplementum. SN - 0065-1699. ER - ...
What does it mean to absorb safely? Well, despite its purification by cleansing acid in the stomach, the mashed up, churned up chyme flowing through the jejunum still has some bacteria in it, so the jejunums lining (and, indeed, the lining of the rest of the intestine) must provide an unbroken barrier between the lumen (the inside of the intestine) and the bloodstream. Nutrients can only cross that barrier by passing (or being pulled) across it. Since only a limited amount of material can pass through a given area, absorption in the jejunum is a game of surface area. More surface area means more cells, means more absorption. Consequently, the jejunum (and the ileum after it) has tiny little projecting folds called villi-from the Latin, meaning "shaggy hair". As you can see in the figure below, all those little crypts and folds cover more area than a level surface ...
The jejunum is a section of the small intestine between the duodenum and the ileum. It is between 1 and 2 meters long.The term "jejunum" derives from the Latin "jejunus," which means "empty of food," "meager," or "hungry." The ancient Greeks noticed at death that this part of the intestine was always empty of food. Hence, the name the jejunum.. The Latin "jejunus" also gave rise to "jejune" means lacking in nutritive value and devoid of substance, significance or interest, that is dull. A jejune argument is one that is empty (like the jejunum) and totally devoid of interest.. ...
What is Jejunum? It is one of the 3 parts of the small intestine. The middle segment between the duodenum and the ileum is known as jejunum, found in all upper-level vertebrates like birds, reptiles, mammals including human. Jejunum Location Although the jejunum is anatomically well distinguished from the duodenum by
In einer frfiheren Arbeit 1, 2 konnten wir den Nachweis erbringen, dab in den hinteren Wurzeln des Menschen entgegen dem Bell… Expand ...
The jejunum is the middle section of the small intestine. The jejunum lies between the duodenum and the ileum.. Brookelyns stomach stopped working and they had to place a feeding tube directly into her jejunum. ...
Define jejunum: the section of the small intestine that comprises the first two fifths beyond the duodenum and that is larger, thicker-walled, and…
To study whether treatment with heparin (HEP) attenuates intestinal dysfunction caused by ischemia (I) and reperfusion (R), rats were treated with HEP (100 U/kg intravenously) or saline solution (SS) before I (60 min), which was produced by occlusion of the superior mesenteric artery, and R (120 min). After I or I/R, we mounted 2-cm jejunal segment in an organ bath to study neurogenic contractions stimulated by electrical pulses or KCl, using a digital recording system. Thin jejunal slices were stained with hematoxylin and eosin for optical microscopy. Compared with the sham group, jejunal contractions were similar in the I + HEP and the I/R + HEP groups, but reduced in the I + SS and the I/R + SS groups. the jejunal enteric nerves were damaged in the I + SS and the I/R + SS, but not in the I + HEP and the I/R + HEP cohorts. These results suggested that HEP attenuated intestinal dysfunction caused by I and I/R ...
Bekijk Stockfoto van Closeup Of The Tongueshaped Villi Of The Jejunum Region Of The Small Intestine As Viewed From The Lumen. Ga voor hoogwaardige fotos met een hoge resolutie naar Getty Images.
Small Intestine: (Jejunum and Ileum) 6 m long. Upper 2/5 make up jejunum & lower 3/5 is ileum. Jejunum begins at DJ junction & ileum ends at ileocecal junc. Distinctive features, but a gradual change from one to other. They are freely mobile & are attached to post. abdominal wall by fan-shaped mesentery. Root of the mesentery permits entrance & exit of branches of superior mesenteric artery and vein, lymph vessels and nerves. Small intestine wall contains plicae circulares, which are larger, more numerous, and closely set in jejunum, While in the upper part of the ileum they are smaller and more widely separated and in the lower part they are absent.
0DHA02Z is a billable procedure code used to indicate the performance of insertion of monitoring device into jejunum, open approach. Code valid for the year 2020
The adherent culture of EGC cells featured in this section was immunofluorescently labeled with anti-vinculin mouse monoclonal primary antibodies followed by goat anti-mouse Fab heavy and light chain fragments conjugated to Rhodamine Red-X.
An investigation of rat jejunal and distal colonic electrolyte transport in-vitro was undertaken using an Ussing chamber prepartion. Selective α2-adrenoceptor stimualtion in the jejunum was found to depress theo-phylline elevated anion secretion, as evidenced by decreases in short- circuit current (SCC). or α1 -Adrenoceptor stimulation, after α2 -adrenoceptor antagonism in the jejunum, evoked transient increases in basal anion secretion, as reflected by transient increases in basal SCC. The use of the neurotoxin tetrodotoxin indicated that this was a direct epithelial secretory effect. 5-hydroxytryptamine (5-HT) on the jejunum elicited transient increases in basal anion secretion, as demonstrated by transient increases in basal SCC. The use of tetrodotoxin, reserpine and α1 -adrenoceptor antagonists, indicated that a major component of this epithelial secretory effect by 5-HT, was associated with activation of intramural nervous pathways of the sympathetic nervous system, ultimately ...
The 6.5 x 5.5 x 4.5 cm mass attached to, but did not invade, the mid-jejunum. The cut-surface is poorly circumscribed with cystic changes and oozing blood ...
Methods, systems, and apparatus for delivering drugs and other substances to extraluminal tissue surrounding a body lumen are described. Catheters are used to inject the drug or other substance intraluminally into tissue surrounding a stent or other luminal scaffold. The drug or other substance is injected in an amount sufficient to cause diffusion back through the tissue to the stent. An absorptive structure, reservoir, or the like, on the stent then absorbs excess drug as it passes from the luminal tissue. In this way, the stent is first loaded with drug. After time, as the stent becomes fully loaded and the tissue becomes depleted, drug will be begin to flow back from the stent into the surrounding luminal tissue.
Biomerics offers numerous multi-lumen extrusion configurations including single lumen, dual & triple lumen, and steerable/guidance extrusions.
Einleitung: Die Pankreasanastomose ist die Achillesferse der Pankreasresektion insbesondere beim weichen Pankreas. Es wurden viele unterschiedliche Techniken in der Literatur beschrieben. Zu den häufigsten angewendeten Techniken gehören die Anastomosierung des Pankreas zum Jejunum entweder[for full text, please go to the a.m. URL ...
Growth kinetics and collagen production were determined in smooth muscle cells isolated from human jejunum and maintained in cell culture. Collagen synthesis increased during the first 15 days in culture at a time when the rate of cell proliferation was maximal. When confluent, these cells produced significantly more collagen than human dermal fibroblasts cultured under identical conditions. The smooth muscle cells required daily replenishment of ascorbate for maximal collagen synthesis. The types of collagen produced by human intestinal smooth muscle cells in culture were the same as those collagens extracted from strictured human bowel (types I, III, and V). These findings suggest that collagen production by human intestinal smooth muscle cells has a role in the repair as well as the fibrosis of the gastrointestinal tract. © 1987 ...
Objective- Comparative endoscopic evaluation of two reconstructive methods (R&Y and jejunal loop interposition) after gastrectomy in dogs. Design- Experimental study. Animals- Ten healthy male dogs. Procedures- The animals were divided randomly in two groups. After a 12 hour food with hold and under general anesthesia laparotomy is performed in all dogs. In group A (R&Y), after dissection and resection of all gastric vessels and ligaments the stomach was resected cranially close to cardia and caudally close to pylorus. After gastrectomy duodenal end was closed in a two layer inverting suture pattern. Then a loop of jejunum 20 cm distal to Treitz ligament was identified and resected. End to side anastomosis was performed between the distal jejunal end and remained part of the stomach. The proximal jejunal end was end to side anastomosed to the rest of jejunum. In group B (JLI), gastrectomy was done in the same manner. The 20 cm length of jejunum was resected from a 20 cm distance to Treitz
TY - JOUR. T1 - Jejunoileal bypass. T2 - A reversible cause of dementia. AU - Reynolds, A. F.. AU - Villar, H. V.. AU - Kasniak, A. W.. PY - 1981/1/1. Y1 - 1981/1/1. N2 - Neurological complications consisting of recent memory loss, visuospatial disorientation, and poor concentration disabled three patients years after a jejunoileal bypass for morbid obesity. The metabolic evaluation and computed tomography gave normal results. The neurological dysfunction cleared completely after reconstruction of the normal intestinal anatomy. Neurological recovery was documented by formal neuropsychological testing.. AB - Neurological complications consisting of recent memory loss, visuospatial disorientation, and poor concentration disabled three patients years after a jejunoileal bypass for morbid obesity. The metabolic evaluation and computed tomography gave normal results. The neurological dysfunction cleared completely after reconstruction of the normal intestinal anatomy. Neurological recovery was ...
BACKGROUND: Cholera toxin produces intestinal secretion by activation of the adenylate cyclase complex. However animal studies have shown 5-hydroxytryptamine may be released after exposure to cholera toxin, and thereby contribute to the secretory state. AIM: To determine whether cholera toxin releases 5-hydroxytryptamine in human jejunum. SUBJECTS: Seven male subjects were given a subclinical dose of cholera toxin in a paired, controlled, randomised, double blind study. METHODS: A closed 10 cm segment of upper jejunum was exposed to 15 micrograms of cholera toxin for two hours prior to closed segment perfusion with plasma electrolyte solution containing a non-absorbable volume marker, [14C]-polyethylene glycol. 5-Hydroxytryptamine in jejunal effluent and 5-hydroxyindoleacetic acid in urine (up to seven hours after cholera toxin) were measured by high performance liquid chromatography with fluorimetric detection. RESULTS: In contrast with controls, all subjects secreted fluid in response to ...
TY - JOUR. T1 - Hydrogen sulfide is a partially redox-independent activator of the human jejunum Na+ channel, NAv1.5. AU - Strege, Peter R.. AU - Bernard, Cheryl E.. AU - Kraichely, Robert E.. AU - Mazzone, Amelia. AU - Sha, Lei. AU - Beyder, Arthur. AU - Gibbons, Simon J.. AU - Linden, David R.. AU - Kendrick, Michael L.. AU - Sarr, Michael G.. AU - Szurszewski, Joseph H.. AU - Farrugia, Gianrico. PY - 2011/6/1. Y1 - 2011/6/1. N2 - Hydrogen sulfide (H2S) is produced endogenously by L-cysteine metabolism. H2S modulates several ion channels with an unclear mechanism of action. A possible mechanism is through reduction-oxidation reactions attributable to the redox potential of the sulfur moiety. The aims of this study were to determine the effects of the H2S donor NaHS on Nav1.5, a voltage-dependent sodium channel expressed in the gastrointestinal tract in human jejunum smooth muscle cells and interstitial cells of Cajal, and to elucidate whether H2S acts on Nav1.5 by redox reactions. Whole cell ...
TY - JOUR. T1 - Early phase microvascular interactions in rat jejunum between nitric oxide and vasopressin following indomethacin administration. AU - László, F.. AU - Whittle, B. J R. PY - 1998. Y1 - 1998. N2 - The involvement of endogenous vasopressin in the actions of indomethacin following the concurrent administration of the nitric oxide (NO) synthase inhibitor, N(G)-nitro-L-arginine methyl ester (L-NAME), on acute intestinal microvascular permeability has been investigated in the rat. Administration of indomethacin (10 mg/kg, s.c.) or L-NAME (10 mg/kg, s.c.) alone did not affect jejunal and ileal vascular permeability after 1 h, as determined by the leakage of radiolabelled serum albumin. In contrast, when indomethacin (10 mg/kg, s.c.) was injected concurrently with L-NAME (2-10 mg/kg, s.c.), significant dose-dependent plasma leakage occurred in the jejunum. Pretreatment with L-arginine (300 mg/kg s.c.) 15 min prior to L-NAME prevented these changes in microvascular permeability. ...
Histochemical researches on appositio slides and tissue sections demonstrated that brownish pigment previously observed by the Authors in the human jejunal mucosa and in lymph nodes from normal cattle is basophilic, acid-fast (long Ziehl-Neelsen), not metachromatic and not sudanophilic. On the contrary the pigment shows reduction sites, carboxil groups or oxy-acid; it does not demonstrate aldehydes, ketones, and proteins-end groups; it does not contains iron, bile and carotenoid-pigment, and hemofuscin. Besides, the pigment is not soluble in acids, alkali and various solvents, and may be not bleached by chlorate, H2O2 and 40% peracetic acid; it does not polarize the light and it is not fluorescent. The Authors suggest that pigment is a particular type of lipofuscin in a mittle stage of oxidation, PAS negative and acid-fast which may be classified at an intermediate level between lipofuscin sensu strictu and melanin, likewise of the pseudomelanosis pigment and considered of exogenous origin. (Author)
With the index finger of the left hand above and the thumb below compressing the specimen to be excised, the surgeon applies right-angle clamps in pairs to the strand of tissue that extends from the portal vein into the pancreas (Figure 24). Within this strand of tissue, there are a number of small veins that must be ligated very carefully lest troublesome bleeding occur. All areas should be ligated to keep the specimen as free of clamps as possible while the third portion of the duodenum is freed from the region of the ligament of Treitz and the superior mesenteric vein and artery (Figure 25). This can be one of the most difficult steps in the procedure. An incision into the peritoneum about the third portion of the duodenum produces an opening directly into the general peritoneal cavity, through which the upper jejunum eventually will be pulled for the anastomosis (Figure 25). The blood supply in the mesentery to the third part of the duodenum and adjacent jejunum is very short, and it is ...
BACKGROUND & AIMS: Patterning of the small intestinal epithelium along its cephalocaudal axis establishes three functionally distinct regions: duodenum, jejunum, and ileum. Efficient nutrient assimilation and growth depend on the proper spatial patterning of specialized digestive and absorptive functions performed by duodenal, jejunal, and ileal enterocytes. When enterocyte function is disrupted by disease or injury, intestinal failure can occur. One approach to alleviate intestinal failure would be to restore lost enterocyte functions. The molecular mechanisms determining regionally defined enterocyte functions, however, are poorly delineated. We previously showed that GATA binding protein 4 (GATA4) is essential to define jejunal enterocytes. The goal of this study was to test the hypothesis that GATA4 is sufficient to confer jejunal identity within the intestinal epithelium. METHODS: To test this hypothesis, we generated a novel Gata4 conditional knock-in mouse line and expressed GATA4 in the ...
BACKGROUND & AIMS: Patterning of the small intestinal epithelium along its cephalocaudal axis establishes three functionally distinct regions: duodenum, jejunum, and ileum. Efficient nutrient assimilation and growth depend on the proper spatial patterning of specialized digestive and absorptive functions performed by duodenal, jejunal, and ileal enterocytes. When enterocyte function is disrupted by disease or injury, intestinal failure can occur. One approach to alleviate intestinal failure would be to restore lost enterocyte functions. The molecular mechanisms determining regionally defined enterocyte functions, however, are poorly delineated. We previously showed that GATA binding protein 4 (GATA4) is essential to define jejunal enterocytes. The goal of this study was to test the hypothesis that GATA4 is sufficient to confer jejunal identity within the intestinal epithelium. METHODS: To test this hypothesis, we generated a novel Gata4 conditional knock-in mouse line and expressed GATA4 in the ...
Iron in the diet is absorbed (5 to 10%) by the intestinal epithelial cells (mainly duodenum and upper jejunum) and then it goes into the blood and utilized by the RBCs in the bone marrow ...
Read independent reviews on Bovine Small Intestine, Jejunum Total Protein from AMS Biotechnology (Archived Products) on SelectScience
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The aim of the present study was to investigate the segment- and time-related changes in rat short bowel syndrome and construct a 4-dimensional (4D) geometrical model of intestinal adaptation. Sprague-Dawley rats were divided into 3 groups: 2-day, 7-day, and 15-day postresection groups in which 75% of the jejunoileum was removed. Histological and morphometrical parameters in the remaining proximal to distal intestinal segments, from the jejunum to the distal colon, were comparatively evaluated in the groups. The data were used to construct a 4D geometric model in which villi were considered as cylinders, and their surface area was expressed as cylinder lateral area. Major adaptive changes were observed in the ileum consisting of an increase in both the diameter of base and the height of villi. A parallel reduction in their number/mm was observed. The resulting ileal architecture was characterized by a limited number of large villi. An opposite pattern was observed in the jejunum whose ...
In order to characterize peptide transport in the ovine small intestine, [14C]-glycyl-sarcosine uptake by tissue collected from five sheep was studied through the use of brush border membrane vesicles (BBMV). Preliminary experiments determined that incubation in hyaluronidase is not necessary in order to separate mucosal tissue from the basement membrane and that the stop solution used in the uptake study needed to be buffered. Uptake was examined in proximal (denoted jejunal) and distal (denoted ileal) halves of the intestine at four times (15, 30, 45, and 60 s) and at three extravesicular pH levels (6.4, 7.0, and 7.5). An intravesicular pH of 7.5 was used throughout the study. The two tissue sites differed (P < .02), with BBMV from jejunal tissue showing greater uptake than ileal. Uptake plateaued after 45 s, resulting in a quadratic (P < .005) effect of time. The effect of changes in extravesicular pH was also quadratic (P < .04), with uptake being greatest at pH 6.4, lowest at pH 7.0 and ...
Jill M. Addison, D. Burston, D. M. Matthews, J. W. Payne, S. Wilkinson; Evidence for Active Transport of the Tripeptide Glycylsarcosylsarcosine by Hamster Jejunum in Vitro. Clin Sci Mol Med 1 June 1974; 46 (6): 30P. doi: https://doi.org/10.1042/cs046030P. Download citation file:. ...
The intestine plays key roles in maintaining body arginine (Arg) homoeostasis. Meanwhile, the intestine is very susceptible to reactive oxygen species. In light of this, the study aimed to explore the effects of Arg supplementation on intestinal morphology, Arg transporters and metabolism, and the potential protective mechanism of Arg supplementation in piglets under oxidative stress. A total of thirty-six weaned piglets were randomly allocated to six groups with six replicates and fed a base diet (0·95 % Arg,) or base diet supplemented with 0·8 % and 1·6 % l-Arg for 1 week, respectively. Subsequently, a challenge test was conducted by intraperitoneal injection of diquat, an initiator of radical production, or sterile saline. The whole trial lasted 11 d. The diquat challenge significantly decreased plasma Arg concentration at 6 h after injection (P,0·05), lowered villus height in the jejunum and ileum (P,0·05) as well as villus width and crypt depth in the duodenum, jejunum and ileum ...
, Human Small intestine (Normal) tissue lysate, GTX27049, Applications: ELISA, IP, WB; ELISA, Immunoprecipitation, Western Blot (WB); CrossReactivity:
The term GIST was introduced by Mazur and Clark in 1983 in order to indicate a distinct heterogeneous group of mesenchymal neoplasms of spindle or epithelioid cells of varying differentiation [5]. GISTs account for only 1-3% of gastric tumours, 20% of small bowel tumours, and 1% or less of colorectal tumours. They have a predilection for adults older than 50 years, with the median ages varying around 60 years. Although these tumours usually develop in a sporadic fashion, familiar occurrence has also been reported [6].. Random genetic mutations are the apparent cause of GISTs. The majority of these tumours show identified mutations in cell-surface proteins called tyrosine kinase receptors [4]. Most GISTs show mutations in a gene that produces a growth factor receptor called KIT [6].. Primary GISTs may occur anywhere along the GI tract from the esophagus to the anus [7]. The most frequent site is the stomach (55%), followed by the duodenum and small intestine (30%), esophagus (5%), rectum (5%), ...
The new JB Academy range of general purpose digital water baths from Grant incorporate Set and Forget™ technology for fast heat and accurate temperature control and simple to use controls with a bright and clear display. Available in 3 sizes from 5L to 18
Duodenum and Jejunum meet. There is a little hook that leads into the Jejunum that they could not get the tube over. This happens most of the time in reviewing the history Elias has with NJ tubes. GI had to be consulted to see if this was acceptable. It had to be, but it isnt the best scenario, not from a feeds aspect, but a dislodging point of view. Here it is easier to slip out of the desired feeding target area. By the time Elias returned to the room it was after 6pm. The decision was made to keep Elias overnight start his feeds at a slow rate and work up to full feeds to see that he tolerated them and there were no more issues with the NJ. Earlier in the afternoon we had a leak of some kind from the G-tube stoma. Not exactly sure what is was but the color was darker than it should have been for someone who had been without fluid 10 hours the day before and only had clear liquids for 16 hrs. The doctors looked at Elias and the leakage which was soaking his bed at this point. It was a very ...
Every attempt was made to provide correct information and labelling, however any liability for eventual errors or incompleteness is rejected! ...
As the biologic complexity of tumor growth and metastasis is explored in greater detail, it has become apparent that key aspects of tumor biology can be explained only by a detailed understanding of how various types of host cells contribute to tumor progression. The work presented here describes how recruited host cells can affect the behavior of cancer cells that have traveled from primary tumors to a distant anatomical site, specifically the lungs. Such effects, by necessity, reflect changes in the systemic physiology of tumor-bearing hosts and govern later steps of the invasion-metastasis cascade. More specifically, we find that Ly6G+ neutrophils can increase metastatic seeding in at least two distinct ways: (i) by inhibiting NK-cell cytotoxic activity, the neutrophils can protect intraluminally trapped tumor cells from rapid clearance by these innate immune cells, and (ii) by expediting extravasation. Both of these mechanisms contribute to the ultimate formation of metastases by increasing ...
cateter triple lumen 12f 3 vias, mac 2 luces con cap. m/mant. de s-gan z, cat. si-21142 2505 000 0793 cateter infusion rapida, cat. rc-09700 2505 000 0794 ...
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