We show that although the currently available isochore mapping methods agree on the isochore classification of about two-thirds of the human DNA, they produce significantly different results with regard to the location of isochore boundaries and isochore length distribution. We present a new consensus isochore assignment method based on majority voting and provide IsoBase, a comprehensive on-line database of isochore maps for all completely sequenced vertebrate genomes.
4Dipartimento di Biochimica e Biologia Molecolare, Università di Bari, Italy. The AUG start codon context features have been investigated by analyzing eukaryotic mRNAs belonging to various taxonomic groups. The functional relevance of each specific position surrounding the AUG start codon has been established as a function of the measured shift between base composition observed at that particular position, and base composition averaged over all the 5 untranslated regions. A more detailed analysis carried out on human genes belonging to different isochores showed significant isochore-specific features that cannot be explained only by a mutational bias effect.. The most represented heptamers spanning from position -3 to +4 with respect to the initiator AUG have been determined for mRNAs belonging to different taxonomic groups and a web page utility has been set up (http://bigarea.area.ba.cnr.it:8000/BioWWW/ATG.html) to determine the relative abundance of a user submitted oligonucleotide context ...
Isometric-line definition, Physics.. Also, isochor. Also called isometric, isometric line. for a given substance, a curve graphing temperature against pressure, when the volume of the substance is held constant. See more.
TY - JOUR. T1 - Polarized THG Microscopy Identifies Compositionally Different Lipid Droplets in Mammalian Cells. AU - Bautista, Godofredo. AU - Pfisterer, Simon G.. AU - Huttunen, Mikko J.. AU - Ranjan, Sanjeev. AU - Kanerva, Kristiina. AU - Ikonen, Elina. AU - Kauranen, Martti. PY - 2014/11/18. Y1 - 2014/11/18. KW - MOLECULAR-STRUCTURE DETERMINATION. KW - INTEGRAL MEMBRANE-PROTEINS. KW - ERYTHROPOIETIN RECEPTOR. KW - TRANSMEMBRANE DOMAIN. KW - SIGNAL-TRANSDUCTION. KW - NMR-SPECTROSCOPY. KW - XPLOR-NIH. KW - DIACYLGLYCEROL KINASE. KW - DETERGENT MICELLES. KW - ACTIVATION. KW - 3111 Biomedicine. U2 - 10.1016/j.bpj.2014.10.009. DO - 10.1016/j.bpj.2014.10.009. M3 - Article. VL - 107. SP - 2230. EP - 2336. JO - Biophysical Journal. JF - Biophysical Journal. SN - 0006-3495. IS - 10. ER - ...
TY - JOUR. T1 - Architecturally-induced tricontinuous cubic morphology in compositionally symmetric miktoarm starblock copolymers. AU - Tselikas, Yiannis. AU - Hadjichristidis, Nikolaos. AU - Lescanec, Robert L.. AU - Honeker, Christian C.. AU - Wohlgemuth, Meinhard. AU - Thomas, Edwin L.. PY - 1996/5/6. Y1 - 1996/5/6. N2 - We report the synthesis and morphological characterization of a miktoarm block copolymer architecture: (PSαM-PIM)n-(PSM-PI αM)n, where M ∼ 20 000, n = 1, 2, and the arm asymmetry parameter α = 1, 2, or 4 (α is the ratio of the outer block molecular weight to that of the inner block). These block copolymers are symmetric in overall composition and exhibit n- and α-dependent microdomain morphologies. Alternating lamellae are observed for linear tetrablocks (n = 1), α = 1, 2, 4, and for inverse starblock (n = 2), α = 1, 2. An architecturally-induced morphological transition from lamellae to a tricontinuous cubic structure is observed with n = 2 and α = 4. The formation ...
The species page of Aedes aegypti str. Liverpool. Also known as Stegomyia aegypti or yellow fever mosquito. Information about genome files, completeness, GC-content, size, N50-values, and sequencing methods are listed.
The species page of Colletotrichum sublineola CgSl1. Also known as Colletotrichum sublineolum. Information about genome files, completeness, GC-content, size, N50-values, and sequencing methods are listed.
Let (a_n) be a bounded sequence and define the set S={x belong to R: x| a_n for infinitely many terms a_n}. show that there exists a subsequence(a_nk) converging to s=sup.
Given the importance of early recognition in rheumatoid arthritis, the most accurate indicator is stiffness, not pain, writes Dr Adam Bajkowski.
In molecular biology and genetics, GC-content (or guanine-cytosine content) is the percentage of nitrogenous bases on a DNA molecule that are either guanine or cytosine (from a possibility of four different ones, also including adenine and thymine).[1] This may refer to a specific fragment of DNA or RNA, or that of the whole genome. When it refers to a fragment of the genetic material, it may denote the GC-content of part of a gene (domain), single gene, group of genes (or gene clusters), or even a non-coding region. G (guanine) and C (cytosine) undergo a specific hydrogen bonding, whereas A (adenine) bonds specifically with T (thymine). The GC pair is bound by three hydrogen bonds, while AT pairs are bound by two hydrogen bonds. DNA with high GC-content is more stable than DNA with low GC-content; however, the hydrogen bonds do not stabilize the DNA significantly, and stabilization is due mainly to stacking interactions.[2] In spite of the higher thermostability conferred to the genetic ...
Natural selection appears to discriminate among synonymous codons to enhance translational efficiency in a wide range of prokaryotes and eukaryotes. Codon bias is strongly related to gene expression levels in these species. In addition, between-gene variation in silent DNA divergence is inversely correlated with codon bias. However, in mammals, between-gene comparisons are complicated by distinctive nucleotide-content bias (isochores) throughout the genome. In this study, we attempted to identify translational selection by analyzing the DNA sequences of alternatively spliced genes in humans and in Drosophila melanogaster. Among codons in an alternatively spliced gene, those in constitutively expressed exons are translated more often than those in alternatively spliced exons. Thus, translational selection should act more strongly to bias codon usage and reduce silent divergence in constitutive than in alternative exons. By controlling for regional forces affecting base-composition evolution, this ...
Adsorption: physisorption and chemisorption. Activated complex. Localized and non-localized ad-sorption. Observables: isotherms, isobares, isochores. The two-dimenasional gas approach: Hil-de Boer equation. Localised sites: the Langmuir model. The silica isolated hydroxyl as ideal site. Structural heterogeneity: the local isotherm approach. Freundlich and Temkin equations. Calorimetry: heat of adsorption in the various cases. Induced heterogeneity: similarity with the Ising problem. Mean field approximation: the Fowler-Guggenheim equation. Comparison with the Onsager solution ...
The four bases found in DNA are adenine (A), cytosine (C), guanine (G) and thymine (T). In genetics, GC-content is the percentage of Guanine (G) and Cytosine (C) bases on a DNA molecule that are ...
In computer science, string is often used as a synonym for sequence, but it is important to note that substring and subsequence are not synonyms. Substrings are consecutive parts of a string, while subsequences need not be. This means that a substring of a string is always a subsequence of the string, but a subsequence of a string is not always a substring of the string, see ...
Maybe it will sound strange but, I didnt eat anything ( in past 3-4 hours at evening time) and tested my GC Level after 1 cup of hot tea ( no sugar added, Caffeine free) And i got 88. After in 20 m...
The silencing protein is a Salmonella histone-like protein called H-NS. The group was searching for direct targets of this known repressor when they noticed that the H-NS binding sites were GC poor (∼47%) compared with the rest of the chromosome (∼52%). A GC-poor foreign gene that the group recombined into Salmonella was also repressed by H-NS. ...
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MON 87460 contains a gene that expresses cold shock protein B (CSPB) from Bacillus subtilis. Expression of this gene confers a yield advantage when yield is limited by water availability. Compositional analyses of MON 87460 and a conventional corn variety with similar background genetics were conduc …
Nokia sites use cookies to improve and personalize your experience and to display advertisements. The sites may also include cookies from third parties. By using this site, you consent to the use of cookies. Learn more ...
By: Rowan Wolf of Uncommon Thought Journal As you have likely already heard, the FDA (U.S. Food & Drug Administration) has determined that cloned meat and milk are compositionally no different from non-cloned meat and milk (FDA Press Release). I would urge people to submit their comments to the FDA. The comment period ends April…
For a set of multiple sequences, their patterns, Longest Common Subsequences (LCS) and Shortest Common Supersequences (SCS) represent different aspects of these sequences profile. Revealing the relationship between the patterns and LCS/SCS might provide us with a deeper view of the patterns. In thi …
Swelling, red patchiness and fluid secretion may be a sign of irritation, not infection. Dont stress! The first thing you need to do is make an appointment with your Hairhouse piercing professional (all part of the Priority Piercing Plan) and if there is an infection, your piercer will advise you on the next steps. Do not remove your jewellery as it may trap the infection inside the piercing channel. Most importantly, keep the area as clean and as dry as possible and we can help with the rest ...
Businesses need a way to support digital transformation with high-quality content at scale - and dentsus Content Symphony is the answer. Read more here.
Accueil /A Novel Approach to Constrain the Escape Fraction and Dust Content at High Redshift Using the Cosmic Infrared Background Fractional ...
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The present invention pertains to an ethylene interpolymer composition characterized as having a narrow molecular weight distribution (MWD) and optimized compositional uniformity, a process for making such a composition and a fabricated article made from such composition. The novel composition is characterized as having at least two polymer components, the first component having an ATREF peak temperature, T.sub.peak1 and a viscosity average molecular weight, M.sub.v1, and the second component having an ATREF peak temperature, T.sub.peak2, and a viscosity average molecular, M.sub.v2, wherein the temperature differential between T.sub.peak2 and T.sub.peak1 decreases with increased composition density and M.sub.v1 /M.sub.v2 is less than or equal to 1.2. The novel composition is further characterized as having a M.sub.w /M.sub.n of less than or equal to 3.3 as determined by gel permeation chromatography, an I.sub.10 /I.sub.2 |6.6, and a composition density
Because of polymer complexity, property variability must be taken into consideration. In this section, we will discuss possible sources of polymer inconsistency and offer suggestions to recognize and reduce these errors. Chemical or compositional heterogeneity refers to the chemical or structural difference among chains of the same polymer. Thus a measured property of a chemically heterogeneous sample will be an averaged value dependent upon sample source. For chemically homogeneous samples, property variability will not be a concern. In a similar fashion, polymers that are polydisperse in molecular weight have averaged property values, while monodisperse samples will give accurate data. Obviously, samples that are both chemically homogeneous and monodisperse will give the most accurate and precise values. As compared to synthetic polymers, almost all nucleic acids and mammalian proteins are compositionally (chemically) homogeneous and monodisperse, if not there would be no life; biopolymers ...
We investigate what possessives mean by examining a wide range of English examples, pre- and postnominal, quantified and non-quantified, to arrive at general, systematic truth conditions for them. In the process, we delineate a rich class of paradigmatic possessives having cross-linguistic interest, exploiting characteristic semantic properties. One is that all involve (implicit or explicit) quantification over possessed entities. Another is that this quantification always carries existential import, even when the quantifier over possessed entities itself doesnt. We show that this property, termed possessive existential import, is intimately related to the notion of narrowing \cite{barker95}. Narrowing has implications for compositionally analyzing possessives meaning. We apply the proposed semantics to the issue of definiteness of possessives, negation of possessives, partitives and prenominal possessives, postnominal possessives and complements of relational nouns, freedom of the possessive ...
Founded in 1920, the NBER is a private, non-profit, non-partisan organization dedicated to conducting economic research and to disseminating research findings among academics, public policy makers, and business professionals.
Пружины рессорного подвешивания грузовых вагонов с применением объёмно-поверхностной закалки.
TY - JOUR. T1 - Fluid Inclusion Characteristics of Auriferous Quartz Veins in Archean and Paleoproterozoic Greenstone Belts of Eastern and Southern Finland. AU - Matti, Poutiainen. AU - Sami, Partamies. PY - 2003. Y1 - 2003. N2 - Fluid inclusions in auriferous quartz veins in five deposits in the Archean (2.9-2.7 Ga) and Paleoproterozoic (2.0-1.75 Ga) greenstone belts of eastern and southwestern Finland have been characterized on the basis of their composition, reconstructed isochores, and decrepitation behavior.The dominant fluids associated with gold mineralization are H2O-CO2 ± CH4 ± halite (Archean) and H2O-CO2-CH4 or H2O-CH4 (Paleoproterozoic) in composition; phase ratios were generally uniform H2O/CO2 in the Archean but were variable in the Paleoproterozoic. In the Archean Au ± sulfide quartz veins, the mineralizing fluids contain less CH4 (,30 mol %) and have higher salinities (up to 39 wt % NaCl equiv) than the corresponding fluids in the Paleoproterozoic Au-sulfide-quartz veins (up ...
Author Summary Genomic survey of microbes by 16S rRNA gene sequencing and metagenomics has inspired appreciation for the role of complex communities in diverse ecosystems. However, due to the unique properties of community composition data, standard data analysis tools are likely to produce statistical artifacts. For a typical experiment studying microbial ecosystems these artifacts can lead to erroneous conclusions about patterns of associations between microbial taxa. We developed a new procedure that seeks to infer ecological associations between microbial populations, by 1) taking advantage of the proportionality invariance of relative abundance data and 2) making assumptions about the underlying network structure when the number of taxa in the dataset is larger than the number of sampled communities. Additionally, we employed a novel tool to generate biologically plausible synthetic data and objectively benchmark current association inference tools. Finally, we tested our procedures on a large
The aim of this Priority Programme is to develop CCA and HEA with outstanding mechanical properties or displaying unusual phenomena, which cannot be obtained in conventional alloys, or be explained by current textbook-level theory. Within this programme, alloys with five or more elements are targeted, each having a concentration between 5 and 35 at. %.. The Priority Programme will comprise two branches:. ...
An important unanswered question in evolutionary genomics is the source of considerable variation of genomic base composition (GC content) even among organisms that share one habitat. Evolution toward GC-poor genomes has been considered a major adaptive pathway in the oligotrophic ocean, but GC-rich bacteria are also prevalent and highly successful in this environment. We quantify the contribution of multiple factors to the change of genomic GC content of Ruegeria pomeroyi DSS-3, a representative and GC-rich member in the globally abundant Roseobacter clade, using an agent-based model ...
TY - JOUR. T1 - Manipulation of cellular processing bodies and their constituents by viruses. AU - Pattnaik, Asit K.. AU - Dinh, Phat X.. PY - 2013/6/1. Y1 - 2013/6/1. N2 - The processing bodies (PBs) are a form of cytoplasmic aggregates that house the cellular RNA decay machinery as well as many RNA-binding proteins and mRNAs. The PBs are constitutively present in eukaryotic cells and are involved in maintaining cellular homeostasis by regulating RNA metabolism, cell signaling, and survival. Virus infections result in modification of the PBs and their constituents. Many viruses induce compositionally altered PBs, while many others use specific components of the PBs for their replication. PB constituents are also known to restrict virus replication by a variety of mechanisms. Further, continuing studies in this rapidly emerging field of PB-virus interactions will undoubtedly provide important clues to the understanding of the role of PBs in cellular homeostasis as well as their role in virus ...
LINE ISLANDS - New data from rocks sampled from nine volcanic edifices in the northern Line Islands region, between latitudes 20°N and 6°N, are incompatible with single or multiple hot spot models: the rocks do not become progressively older with distance. Instead, two major episodes of volcanism, each lasting ~5 Ma and separated by ~8 Ma, occurred synchronously over long distances, not just along the main chain but also at nonaligned edifices. Volcanism during the older episode (81-86 Ma) extended over a distance of at least 1200 km along the eastern part of the complex seamount chain. Volcanism during the younger episode (68-73 Ma) was concentrated in the western part of the chain and may have extended over a distance of >4000 km.. Chemical analyses of 68 samples represent a compositionally diverse basaltic suite. The most diverse assemblage of rocks was recovered from a cross-trending seamount chain south of Johnston Atoll. Although compositions of rocks from the two volcanic episodes ...
An important characteristic of human language is compositionality. We can efficiently express a wide variety of real-world situations, events, and behaviors by compositionally constructing the meaning of a complex expression from a finite number of elements. Previous studies have analyzed how machine-learning models, particularly neural networks, can learn from experience to represent compositional relationships between language and robot actions with the aim of understanding the symbol grounding structure and achieving intelligent communicative agents. Such studies have mainly dealt with the words (nouns, adjectives, and verbs) that directly refer to real-world matters. In addition to these words, the current study deals with logic words, such as
IF AN RNA OR PROTEIN MOLECULE is damaged, the cell will typically degrade the entire molecule and replace it with a new one. But cells cannot do this with DNA. A chromosome is too big and the copy number is too low, so it is far more efficient to repair the chromosome than to replace it. If only one DNA strand is damaged, the other may be used as a template for repair; alternatively, if both strands are damaged, the homologous chromosome may be used. DNA repair involves DNA synthesis, sometimes of just 1 nucleotide, and sometimes of thousands or more, depending on the type of damage and the method of repair (Alberts et al. 2002). This repair-associated DNA synthesis has given rise to multiple forms of drive. On the one hand, there is biased gene conversion (BGC). Like other forms of drive, it is a process by which a heterozygote transmits one allele more frequently than the other. This drive does not arise because the gene encodes a protein that acts to bias inheritance; rather, drive arises as a
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Sequence.py. This module provides code to work with sequences.. Classes: AbstractSequence Base class for all sequences. Sequence Basic class that stores sequences as a string. NamedSequence Sequence that has a name. SubSequence Handles subsequencing with different indexing schemes.. ...
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Background. Bacterial genomes possess varying GC content (total guanines (Gs) and cytosines (Cs) per total of the four bases within the genome) but within a given genome, GC content can vary locally along the chromosome, with some regions significantly more or less GC rich than on average. We have examined how the GC content varies within microbial genomes to assess whether this property can be associated with certain biological functions related to the organisms environment and phylogeny. We utilize a new quantity GCVAR, the intra-genomic GC content variability with respect to the average GC content of the total genome. A low GCVAR indicates intra-genomic GC homogeneity and high GCVAR heterogeneity.. Results. The regression analyses indicated that GCVAR was significantly associated with domain (i.e. archaea or bacteria), phylum, and oxygen requirement. GCVAR was significantly higher among anaerobes than both aerobic and facultative microbes. Although an association has previously been found ...
Hard to believe that FIT FOR AN AUTOPSY have been around for just over a decade, but it is true. Playing deathcore at the death knell of that genre s zenith is undoubtedly a bold move and, sure, FFAA released a couple of albums and had some lineup shuffles but for the most part, the band was homogenous. And then, in 2015, without any real rhyme or reason, FIT FOR AN AUTOPSY arrived with Absolute Hope, Absolute Hell, a deathcore record fit for a goddamn coronation. The album was, and is, a delightful riff monster, and if you don t want to scream along to it you re just doing it wrong. Equally as inexplicable, follow up The Great Collapse continued the upward momentum (really, Heads Will Hang hits so hard my brain still has bruises I am sure of it). Now, the band is asking us to dip our toes into The Sea Of Tragic Beasts. Learn to swim.. Morphing beyond mere deathcore, FIT FOR AN AUTOPSY have been consistently pushing their own limits compositionally and lyrically as well as treating their art ...
This incredibly exciting firm, based in Mexico City and headed by chief designer José María Balmaceda, specializes in rugs that are authentic and rooted in global and historical craft traditions. These rugs occupy a unique stylistic position, from which they may center any story both compositionally and conceptually. José María Balmacedas work is the result
The 3-D printed material compositionally, mechanically and biologically mimics the ACL connective tissue, which ranges from ligament to bone.
In February 2020 Paul sent this new piece, and this is what he had to say about it:. The show explores all facets of love (not just the traditional Valentiney ones), so we thought it would be a great time to share this painting with my Columbus friends/family because its about the love I have for my dad. I painted this shortly after he passed away unexpectedly when I was at a conference in Florida several years ago. Even though I didnt see him or even talk to him every day, his absence left an overwhelming emptiness that I struggled to accept (and still do). As I worked on this piece, I kept thinking about the concept of positive and negative space. Its one of the first things you learn in art school. Positive space is the stuff - the subject matter. Negative space is whats around it - the background, the empty part. Most art students start out only wanting to focus on the positive space, but the shapes you create with the negative are just as important compositionally. Losing someone who is ...
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I had a good chuckle over the new content at Microsofts Open XML Community web site. Please take a look. What it lacks in accuracy it makes up for in the
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