TY - JOUR. T1 - A new approach to the study of ion transport processes by an in situ radiotracer method based on measuring intensity changes and energy spectrum alterations of β-radiation. AU - Németh, Z.. AU - Erdei, L.. AU - Kolics, A.. PY - 1995/3. Y1 - 1995/3. N2 - A new approach for the study of ion transport by an in situ radiotracer method is presented. The method is based upon the measurement of the intensity and energy spectrum change of β-radiation during the penetration of labeled species. The applicability of the radiotracer technique is detailed through the measurement of the transport of labeled chloride ions into a PERMAPLEX-A20 anion exchanger membrane. The proposed method is applicable to in situ monitoring of the motion of ions in the membrane (or adsorbent).. AB - A new approach for the study of ion transport by an in situ radiotracer method is presented. The method is based upon the measurement of the intensity and energy spectrum change of β-radiation during the ...
I am conducting my research project and currently stuck at a point where I need to find out about the proteins role in active transport of ion (Na & K) in molecular level detail. Need to know everything about this Na-K ion transport mechanism, Contribution of protein in transport, Why NA & K, How does protein allows certain molecules to pass through and stops others etc....abt proteins ...
Semantic Scholar extracted view of Ion transport across biological membranes and its control. Workshop organized by the Sonderforschungsbereich 160--Eigenschaften biologischer Membranen--September 25-27 1983, Maria Laach, FRG. by B. Deuticke et al.
An ion transport membrane system comprising (a) a pressure vessel having an interior, an exterior, an inlet, and an outlet; (b) a plurality of planar ion transport membrane modules disposed in the interior of the pressure vessel and arranged in series, each membrane module comprising mixed metal oxide ceramic material and having an interior region and an exterior region, wherein any inlet and any outlet of the pressure vessel are in flow communication with exterior regions of the membrane modules; and (c) one or more gas manifolds in flow communication with interior regions of the membrane modules and with the exterior of the pressure vessel. The ion transport membrane system may be utilized in a gas separation device to recover oxygen from an oxygen-containing gas or as an oxidation reactor to oxidize compounds in a feed gas stream by oxygen permeated through the mixed metal oxide ceramic material of the membrane modules.
Measurements of extracellular pH (pHe) in vivo have shown that the microenvironment in tumours is more acidic than in normal tissue. However, both human and animal tumour cells have been shown to have an intracellular pH (pHi) on the alkaline side of neutrality (pH 7.1-7.2). This gives rise to a reversed pH gradient between tumours and normal tissue- which implies that cells within solid tumours are capable of maintaining their level of pHi at physiological levels, despite lower than normal levels of pHe. In this paper the authors describe a mathematical model that provides a possible explanation for the altered pH gradient observed in tumours. The authors examine the infuence of changes in the microenvironment on the activity of several membrane based ion transport systems Using qualitative analysis the authors show that the pHi of tumour cells is less sensitive to external pH than for normal cells, because of their increased reliance on the inefficient glycolytic pathway for energy production. ...
Our primary focus is on real time monitoring of ion transport mechanisms in epithelia, using high-resolution microscopy. One of the crucial problems facing all epithelial cells is the control of the intracellular milieu. In an effort to maintain ionic homeostasis, epithelial cells have devised a variety of ion channels, transport proteins, and carriers to regulate and maintain the intracellular ionic concentrations. To further understand how ions are transported in epithelial cells, we have developed a variety of optical techniques to continuously monitor intracellular ionic concentrations in real time. Using high-resolution video or confocal microscopy we are presently able to monitor intracellular Ca2+, Na+, K+, Cl-, pH, and membrane potential. We are currently investigating various aspects of renal tubule and gastric tissue ion transport in intact renal tubules and gastric glands. We also are characterizing the secretory and reabsorptive properties of the colonic crypt, with a special focus ...
One intriguing finding from theoretical calculations was the electrostatic contribution of K131 in stabilizing the Cl− binding to all three binding sites in ClC-ec1 (Faraldo-Gomez and Roux, 2004) despite the fact that the side chain of K131 does not directly line the ion transport pathway. Faraldo-Gomez and Rouxs calculations pointed out that the single most important favorable ion-side chain electrostatic interaction in ClC-ec1 originates not from the ion-contacting residues such as S107 or Y445 but from K131 (Faraldo-Gomez and Roux, 2004). A lysine residue at this position is conserved from the bacterial to the mammalian ClC proteins. To examine the functional role of the corresponding lysine residue (K149) in ClC-0, we constructed several K149 mutants, including K149E, K149D, K149A, K149L, and K149R. We have so far been unable to functionally express K149E in Xenopus oocytes. Two runs of expression of K149E and K149D mutants in HEK293 cells did not result in functional current within 5 d ...
Kleyman, T.R., Cragoe, E.J. Amiloride and its analogs as tools in the study of ion transport. J. Membrain Biol. 105, 1-21 (1988). https://doi.org/10.1007/BF01871102. Download ...
View Notes - fields_lec9 from BIO 2.797j at MIT. Key Concepts for this section 1: Lorentz force law, Field, Maxwells equation 2: Ion Transport, Nernst-Planck equation 3: (Quasi)electrostatics,
In this study, the effect on thin film growth due to an anomalous electron transport, found in high power impulse magnetron sputtering (HiPIMS), has been investigated for the case of a planar circular magnetron. An important consequence of this type of transport is that it affects the way ions are being transported in the plasma. It was found that a significant fraction of ions are transported radially outwards in the vicinity of the cathode, across the magnetic field lines, leading to increased deposition rates directly at the side of the cathode ( perpendicular to the target surface). Furthermore, this mass transport parallel to the target surface leads to that the fraction of sputtered material reaching a substrate placed directly in front of the target is substantially lower in HiPIMS compared with conventional direct current magnetron sputtering (dcMS). This would help to explain the lower deposition rates generally observed for HiPIMS compared with dcMS. Moreover, time-averaged mass ...
The teleost gill has a key position in the history of the study of epithelial ion transport - the first unequivocal demonstration of ion transport in vitro was the experiments on chloride excretion...
Recent research has shown that nitric oxide (NO) produced by nitric oxide synthases (Nos) is an inhibitor of ion transporter activity and a modulator of epithelial ion transport in fish but little is known on changes in the Nos/NO system during osmotic stress. We hypothesized that the Nos/NO system responds to salinity changes as an integrated part of the acclimation process. Expression and localization of nos1/Nos1 and nos2/Nos2 were investigated in gill, kidney and intestine of FW- and SW-transferred trout using qPCR, Western blotting and immunohistochemistry, along with expressional changes of major ion transporters in the gill ...
Fast Ion Transport in Solids - Proceedings of the NATO Advanced Research Workshop, Belgirate, Italy, September 20-26, 1992 (Hardcover, 1993 ed.) / Editor: Bruno Scrosati / Editor: A. Magistris / Editor: C.M. Mari / Editor: G. Mariotto ; 9780792325147 ; Physical chemistry, Chemistry, Science & Mathematics, Books
Dynamic amphiphiles provide access to transmembrane ion transport, differential sensing and cellular uptake. In this report, we introduce dynamic amphiphiles with fluorescent tails. Core-substituted naphthalenediimides (cNDIs) and perylenediimides (cPDIs) are tested. Whereas the latter suffer from poor partitioning, dynamic cNDI amphiphiles are found to be purifiable by RP-HPLC, to partition selectively into liquid-disordered (Ld) microdomains of mixed lipid bilayers and to activate DNA as transporters. Importantly, fluorescence properties, partitioning and activity can be modulated by changes in the structure of mixed amphiphiles. These results confirm the potential of dynamic fluorescent amphiphiles to selectively label extra- and intracellular membrane domains and visualize biological function.. [open archive unige:21885 • pdf ...
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Oxygen can be recovered from air at high temperatures by passing hot compressed oxygen-containing gas, preferably air, at temperatures above 500oC over ...
What happens with ion transport when the dimensions of the pore become very, very small? How the pores structure influences its transport properties?Motivation
The effects of extracellular ATP on ion fluxes and the intracellular free Ca2+ concentration ([Ca2+]i) were examined using a suspension of rat parotid acinar cells and were contrasted with the effects of the muscarinic agonist carbachol. Although ATP and carbachol both rapidly increased [Ca2+]i about threefold above the resting level (200-250 nM), the effect of ATP was due primarily to an influx of Ca2+ across the plasma membrane, while the initial response to carbachol was due to a release of Ca2+ from intracellular stores. Within 10 s, ATP (1 mM) and carbachol (20 microM) reduced the cellular Cl- content by 39-50% and cell volume by 15-25%. Both stimuli reduced the cytosolic K+ content by 57-65%, but there were marked differences in the rate and pattern of net K+ movement as well as the effects of K+ channel inhibitors on the effluxes initiated by the two stimuli. The maximum rate of the ATP-stimulated K+ efflux (approximately 2,200 nmol K+/mg protein per min) was about two-thirds that of the ...
The pHi (intracellular pH) is an important physiological parameter which is altered during hypoxia and ischaemia, pathological conditions accompanied by a dramatic decrease in pHi. Sensors of pHi include ion transport systems which control intracellular Ca2+ gradients and link changes in pHi to functions as diverse as proliferation and apoptosis. The annexins are a protein family characterized by Ca2+-dependent interactions with cellular membranes. Additionally, in vitro evidence points to the existence of pH-dependent, Ca2+-independent membrane association of several annexins. We show that hypoxia promotes the interaction of the recombinant annexin A2-S100A10 (p11) and annexin A6 with the plasma membrane. We have investigated in vivo the influence of the pHi on the membrane association of human annexins A1, A2, A4, A5 and A6 tagged with fluorescent proteins, and characterized this interaction for endogenous annexins present in smooth muscle and HEK (human embryonic kidney)-293 cells ...
An interesting and perplexing feature of the mosquito larval midgut is that the luminal compartments exhibit one of the highest pH values generated by a biological system. The pH of the luminal contents in mosquito larvae increases from near neutrality in the foregut to a value that exceeds 10 in the anterior midgut then drops to 7.5 in the posterior midgut (Dadd, 1975; Ramsay, 1950). These results are consistent with a vigorous active cycling of base between the gut contents and hemolymph during the digestive cycle, similar to that suggested for lepidopteran larvae (Moffett, 1994). The alkaline environment optimal for mosquito digestive enzymes sterilizes food and dissociates the tannin-protein complexes that are ingested in the plant detritus diet of the larvae (see Clements, 1992).. The generation of large pH gradients along short distances in the absence of morphological barriers is almost certainly the result of region-specific ion transport systems energized by ion-motive ATPases. The ...
The ion transport systems used to regulate acid-base balance are not equally effective in all marine animal groups. Marine organisms are apparently highly tolerant of CO2 when they can accumulate large amounts of bicarbonate ions, which stabilize the pH value. These organisms are usually also able to very effectively excrete protons. Mobile and active species such as fish, certain crustaceans, and cephalopods - cuttlefish, for instance - are therefore especially CO2-tolerant. The metabolic rates of these animals can strongly fluctuate and reach very high levels during exercise (hunting & escape behaviour). The oxygen-consumption rate (a measure of metabolic rate) of these active animal groups can reach levels that are orders of magnitude above those of sea urchins, starfish or mussels. Because large amounts of CO2 and protons accumulate during excessive muscle activity, active animals often possess an efficient system for proton excretion and acid-base regulation. Consequently, these animals can ...
exchange, and K+absorption/H+ secretion mediated by H+-K+-ATPase (3, 40). These transport systems are believed to be nonelectrogenic and thus cannot be assessed fromI sc measurements.. The vasopressin receptor is of two different subtypes, the V1 and V2 receptors (20, 31, 42). The present study has demonstrated that the regulation of three kinds of electrogenic ion transport in the colon by AVP was probably all mediated by the V1 receptor, because they were each inhibited more potently by the V1 than by the V2 receptor antagonist (Table 3) (29, 30). The dissociation constant of AVP for the V1 receptor has been reported to be 0.6-3 nM (42). The ED50value for inhibiting electrogenic Na+ absorption (0.8 nM) was within this range (Fig. 2). The ED50value for activating K+ secretion may also be within this range (0.1-1 nM; Figs. 3 and 5), whereas that for activating Cl−secretion seems to be at a slightly higher value (,10 nM; Fig. 3). It cannot be excluded, however, that there is also the V2 ...
Dr. Pearce Wilcox: Advances in technology have made it feasible for many laboratories to test compounds that might facilitate CFTR function. These referenced studies in cell systems and animal models illustrate the potential in F508del for a class of medications with already established clinical roles - PDE-5 inhibitors. Given that cAMP-dependent chloride conductance in CF epithelial cells is impaired, there is reason to believe that modulating intracellular levels of cAMP could have beneficial therapeutic effects for patients with CF. While an understanding of the mechanisms are limited, there is work to show a partial correction of the basic transepithelial ion transport abnormalities, and mitigation of the exaggerated inflammatory responses related to the F508del-CFTR protein. A wide dose safety margin of these compounds, based especially on work in pulmonary hypertension, has been shown. However, the study of Leier et al suggests that supraphysiologic levels may be needed to potentiate CFTR ...
The bottom line is that, if a true relationship between ion transport (as measured by nasal PD) and the severity of respiratory disease exists, it is likely to be weak. These data are consistent with the notion of a "point of no return"-that is, the ion transport abnormality provides the setting for CF lung disease early in life but, once established, other factors such as non-CFTR gene modifiers, the response of the innate immune system, mucus secretory control mechanisms, or environmental factors are more important in determining disease severity.23. Is this concept important? Certainly; nasal PD has frequently been employed as a surrogate outcome measure for "proof of principle" trials of new treatments.24 If fundamental treatments are to work, these data suggest that early intervention is necessary as other factors may have a more profound influence on the eventual severity of lung disease. If ion transport is to be used as a surrogate outcome for fundamental treatments, then the data from ...
Ligand-gated ion channels (LGICs) are a group of transmembrane ion channel proteins which open to allow ions such as Na+, K+, Ca2+, or Cl- t ...
Ligand-gated ion channels (LGICs) are a group of transmembrane ion channel proteins which open to allow ions such as Na+, K+, Ca2+, or Cl- t ...
A method and apparatus is disclosed for selectively identifying, and targeting with an energy beam, specific cells within a mixed cell population, for the purpose of inducing a response in the targeted cells. Two or more fluorescent labels can be attached to the targeted cells, and distinguished from one another by a color camera. By use of this system, one can monitor and affect cells having a desired phenotype. For example, targeted cells can not only be inactivated by an energy beam, but can also be monitored through fluorescent labeling for changes in cell morphology, ion transport or other cellular functions.
Control of the volume of surface liquid which covers the pulmonary epithelium is critical for normal mucociliary clearance and for efficient gas exchange. The role that active transepithelial ion transport plays as a driving force for liquid movement across the pulmonary airways is currently under study. We measure the bioelectric properties of isolated bronchi and bronchioles as correlates of active ion transport activity. We then use selective transport inhibitors and stimulators to determine which transport pathways are present and how these processes are regulated. In persons afflicted with cystic fibrosis (CF), a molecular defect in an epithelial chloride channel is present that leads to a myriad of pathological problems, the most critical of which involves secretion of thickened, dehydrated mucus into the airways. A major focus of our research is to determine how such defects in chloride ion transport are mechanistically related to the development of the symptoms observed in cystic ...
This research project examines the transport of ions through porous alumina membranes with channels of ̃200 nanometers in diameter. The test molecule is the permeate anion 1,5-naphthalene disulfonate (NDS2-), which as absorbance in the ultraviolet range and also exhibits fluorescence. This allows direct examination of transport by utilizing ultraviolet-visible spectroscopy as well as fluorescence spectroscopy. Adding substituents through strong alumina-silane linkages further modifies all the surfaces of the alumina nanotube membranes. Membranes are soaked in solutions containing either octadecyl trimethoxysilane (ODTMS) or isobutyl trimethoxysilane (IBTMS). Ion transport across the membrane treated with the hydrophobic octadecyl trimethoxysilane was hindered significantly, while the membranes exposed to a short alkyl chain isobutyl trimethoxysilane demonstrated only a slight blockage of ion transport. In both cases, addition of an ionic surfactant dodecyl benzenesulfonate (DBS) and also cationic drug
TY - JOUR. T1 - The extracellular loop of pendrin and prestin modulates their voltage-sensing property. AU - Kuwabara, Makoto F.. AU - Wasano, Koichiro. AU - Takahashi, Satoe. AU - Bodner, Justin. AU - Komori, Tomotaka. AU - Uemura, Sotaro. AU - Zheng, Jing. AU - Shima, Tomohiro. AU - Homma, Kazuaki. PY - 2018/1/1. Y1 - 2018/1/1. N2 - Pendrin and prestin belong to the solute carrier 26 (SLC26) family of anion transporters. Prestin is unique among the SLC26 family members in that it displays voltage-driven motor activity (electromotility) and concurrent gating currents that manifest as nonlinear cell membrane electrical capacitance (nonlinear capacitance (NLC)). Although the anion transport mechanism of the SLC26 proteins has begun to be elucidated, the molecular mechanism of electromotility, which is thought to have evolved from an ancestral ion transport mechanism, still remains largely elusive. Here, we demonstrate that pendrin also exhibits large NLC and that charged residues present in one ...
TY - JOUR. T1 - P2Y2 receptor-mediated inhibition of ion transport in distal lung epithelial cells. AU - Ramminger, S. J.. AU - Collett, A.. AU - Baines, D. L.. AU - Murphie, H.. AU - McAlroy, H. L.. AU - Olver, R. E.. AU - Inglis, S. K.. AU - Wilson, S. M.. PY - 1999/9. Y1 - 1999/9. N2 - 1. Rat foetal distal lung epithelial cells were plated onto permeable supports where they became integrated into epithelial sheets that spontaneously generated short circuit current (I(SC)) 2. Apical ATP (100 μM) evoked a transient fall in I(SC) that was followed by a rise to a clear peak which, in turn, was succeeded by a slowly developing decline to a value below control. Apical UTP evoked an essentially identical response. 3. UDP and ADP were ineffective whilst ATP had no effect when added to the basolateral solution. These effects thus appear to be mediated by apical P2Y2 receptors. 4. The rising phase of the responses to ATP/UTP was selectively inhibited by anion transport inhibitors but persisted in the ...
1. O2 uptake was determined for periods of 23-46 h in salt-depleted crayfish held in deionized water (DW) or Na-free media at 10 degrees C. These media were replaced by artificial lakewater media (ALW) containing 0-2-0-6 mM Na and O2 uptake was again determined for periods of 24-66 h. 2. During net ion uptake in ALW the metabolic rate was either elevated or depressed. Standard metabolism in ALW altered by amounts equivalent to 0-1 - 15-5% (mean 6-4 (15) +/− 4-4% S. D.) of the metabolic rate measured during salt-depletion. On three occasions the metabolic rate was elevated by 22-0 - 66-7%, but some of this increase may have been due to locomotor activity. 3. The calculated values for thermodynamic work involved in ion transport were 0-056 - 0-268 J/10 g. h at 10 degrees C, or 1-5 - 7-2% of the mean standard metabolic rate. Most of the observed changes in metabolic rate lie within the limits of experimental error (ca. +/− 7%). Hence the energetic cost of ion transport is too small for direct ...
1. van der Merwe, J. Q., Moreau, F., and MacNaughton, W. K. Protease-activated receptor-2 stimulates intestinal SCBN epithelial chloride transport through activation of PLC and selective PKC isoforms. Am J Physiol Gastrointest Liver Physiol, 296: G1258-1266, 2009. 2. van der Merwe, J. Q., Ohland, C. L., Hirota, C. L., and MacNaughton, W. K. Prostaglandin E2 derived from cyclooxygenases 1 and 2 mediates intestinal SCBN epithelial ion transport stimulated by the activation of protease-activated receptor 2. J Pharmacol Exp Ther, 329: 747-752, 2009. 3. Dong, X., Smoll, E. J., Ko, K. H., Lee, J., Chow, J. Y., Kim, H. D., Insel, P. A., and Dong, H. P2Y receptors mediate Ca2+ signaling in duodenocytes and contribute to duodenal mucosal SCBN bicarbonate secretion. Am J Physiol Gastrointest Liver Physiol, 296: G424-432, 2009. 4. Buret, A. and Lin, Y. C. Genotypic characterization of an epithelial cell line SCBN for the study of parasite-epithelial interactions. J Parasitol, 94: 545-548, 2008. 5. Smith, ...
Liquid state of low-density pressure-amorphized ice above its Tg. Ion transport in a chemically prepared polypyrrole/poly(styrene-4-sulfonate) composite
Physiologic Instruments designs and manufactures instrumentation, Ussing Chamber Systems and Data Acquisition products for studying transport across epithelial barriers. Transepithelial voltage, short-circuit current and resistance are measured using single and multi-channel voltage/current clamps that may be directly connected to Acquire & Analyze for automating data collection and analysis.
As the third-generation rigid macrocycles evolved from progenitor 1, cyclic aromatic oligoamides 3, with a backbone of reduced constraint, exhibit extremely strong stacking with an astoundingly high affinity (estimated lower limit of K dimer , 10 13 M -1 in CHCl 3), which leads to dispersed tubular stacks that undergo further assembly in solution. Computational study reveals a very large binding energy (-49.77 kcal mol -1) and indicates highly cooperative local dipole interactions that account for the observed strength and directionality for the stacking of 3. In the solid-state, X-ray diffraction (XRD) confirms that the aggregation of 3 results in well-aligned tubular stacks. The persistent tubular assemblies of 3, with their non-deformable sub-nm pore, are expected to possess many interesting functions. One such function, transmembrane ion transport, is observed for 3. ...
Epithelial cells have an apical-basolateral axis of polarity, which is required for epithelial functions including barrier formation, vectorial ion transport and sensory perception. Here we review what is known about the sorting signals, machineries
Ions remain in solution (meaning, dissolved in water) because the attraction forces between the ions and the water is greater than the attraction forces between the ions and other ions. Conversely, ions will come out of solution (forming a precipitate) if the attraction forces are greater between the ions and other ions. This is like a situation where your family (mum, dad, brothers and sisters) may dissociate from each other and mingle when at a family barbecue - whether you choose to stick together or not depends on how much you like to hang out with the other people there ...
Transport authorities will need to audit the data they use in order to understand what it says (and what it does not say) and how it can best be used. ...
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Provided herein are bioactive agents comprising a compound that inhibits the ion transport activity of a cystic fibrosis transmembrane conductance regulator (CFTR) and that is linked to a macromolecule that interacts with a cell that expresses CFTR. The bioactive agents described herein are useful for treating diseases, disorders, and sequelae of diseases, disorders, and conditions that are associated with aberrantly increased CFTR activity, for example, secretory diarrhea.
TY - JOUR. T1 - Receptor function and ion transport in turkey erythrocytes. AU - Gardner, J. D.. AU - Aurbach, G. D.. AU - Spiegel, A. M.. AU - Brown, E. M.. PY - 1976/1/1. Y1 - 1976/1/1. UR - http://www.scopus.com/inward/record.url?scp=0017100817&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0017100817&partnerID=8YFLogxK. M3 - Article. C2 - 785559. AN - SCOPUS:0017100817. VL - Vol. 32. SP - 567. EP - 595. JO - Recent Progress in Hormone Research. JF - Recent Progress in Hormone Research. SN - 0079-9963. ER - ...
A main challenge in stem-cell mediated regenerative medication is the advancement of described culture systems for the maintenance of clinical-grade individual embryonic stem (hES) cells. laboratories possess concentrated on developing described circumstances for hES cell lifestyle4C9. One technique provides been to replace nonhuman items, i.age. pet sera and mouse embryonic Angiotensin (1-7) IC50 fibroblast (MEF) […]. Read More ». ...
Comparison of permeant ion uptake and carotenoid band shift as methods for determining the membrane potential in chromatophores from Rhodopseudomonas sphaeroide
This gene encodes a member of the FXYD family of transmembrane proteins. This particular protein encodes phosphohippolin, which likely affects the activity of Na,K-ATPase. Multiple alternatively spliced transcript variants encoding the same protein have been described. Related pseudogenes have been identified on chromosomes 10 and X. Read-through transcripts have been observed between this locus and the downstream sodium/potassium-transporting ATPase subunit gamma (FXYD2, GeneID 486) locus.[provided by RefSeq, Feb 2011 ...
Zkratka CFTR označuje speciální buněčný membránový receptor (cystic fibrosis transmembrane conductance regulator), který je určen genem stejného názvu, a který je zodpovědný za transport molekul chloru mezi buňkou a okolím. Mutace v CFTR genu mohou způsobit vznik cystické fibrózy ...
The Lencer laboratory studies the cell and molecular biology of vesicular transport in polarized epithelial cells and regulation of ion transport in the intestine. These projects relate to how intestinal epithelial cells interact with the luminal and sub-epithelial microenvironment, and to the biology of bacterial pathogenesis and mucosal host defense.. Lab Members , Research Projects , Publications , Contact Us. ...
Physicochemical Kinetics and Transport at Biointerfaces von Wolfgang Köster und Buchbewertungen gibt es auf ReadRate.com. Bücher können hier direkt online erworben werden.