In a randomized noninferiority trial (TARGIT-A) reported in The Lancet, Jayant S. Vaidya, PhD, and Michael Baum, MD, of University College London, and colleagues compared risk-adapted radiotherapy using single-dose targeted intraoperative radiotherapy vs fractionated external-beam radiotherapy in women with breast cancer. Targeted intraoperative radiotherapy met the noninferiority margin for 5-year local recurrence among all patients and when given concurrently with lumpectomy but not when delayed until after lumpectomy (postpathology). Breast cancer mortality did not differ significantly between the two groups, but targeted intraoperative radiotherapy was associated with reduced non-breast cancer mortality.. Study Details. In this open-label, randomized trial, 3,451 women aged ≥ 45 years with invasive ductal carcinoma were randomly assigned to receive single-dose targeted intraoperative radiotherapy (n = 1,721) or whole-breast external-beam radiotherapy according to standard schedules over ...
Jul 8, 2010. TARGIT delivers local breast cancer control. Recently published results demonstrate that targeted intraoperative radiotherapy (TARGIT), which involves only selective irradiation of the breast, is equally effective in preventing local breast cancer recurrence as conventional whole-breast radiotherapy (Lancet doi: 10.1016/S0140-6736(10)60837-9).. http://medicalphysicsweb.org/cws/article/research/43137. ...
... (IORT) involves treatment with radiation therapy during surgery. The benefit of this method is that less tissue is exposed to radiation. The target area can be directly viewed by your team of oncologists and surgeons, and a more effective dose of radiation may be delivered directly to the tumor. Intraoperative irradiation can be used with many types of tumors, including breast cancer, colorectal cancers, and sarcomas, in order to improve the outcome of cancer treatment. ROA physicians use the Zeiss Intrabeam system to deliver intraoperative radiation treatments. Learn more about the Zeiss Intrabeam System. ...
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A single dose of radiotherapy delivered at the time of surgery by way of targeted intraoperative radiotherapy should be considered as an alternative to external beam radiotherapy delivered over several weeks postsurgery for selected patients with early breast cancer, found a study published online June 5 in the Lancet.
Single-dose intraoperative radiotherapy for early stage breast cancer - Radiation delivered to the tumour site after the tumour is removed.. Choose Spire Parkway Hospital.
Vol 5: Intraoperative use of remifentanil and opioid induced hyperalgesia-acute opioid tolerance: systematic review.. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Procedure: The patient will undergo preoperative sonographic assessment of both ovaries to determine if either ovary is diseased or compromised. Patient will undergo preoperative blood sampling to measure AMH, FSH, LH and estradiol as indicators of current ovarian function (less than 8 teaspoons) if time allows and assessment of ovarian reserve is appropriate; menopausal levels of FSH (≥ 30 miu/ml) will be a contraindication to participation in this study. The patient may have infectious disease testing as part of the evaluation for fertility preservation treatment. Patient will undergo preoperative assessment and clearance for surgery by an anesthesiologist.. Intraoperative management will include laparotomy or laparoscopy, depending on the individual patients history, exam and oncology plans. Removal of one or both ovaries will depend on preoperative ovarian assessment and recommendation of the oncologist. If ovarian survival for the anticipated treatment has never been documented then both ...
In concentrating on TEEs role in assessing acute coronary ischemia and since active ischemia can be seen on a TEE much earlier than any changes in EKG, interpretation of any wall motion abnormalities and how they correlate to coronary artery distribution can be crucial to intraoperative management for an anesthesiologist.. Views. Transgastric Short-Axis View. The short-axis view at the midpapillary muscle level is a commonly used view for evaluating global and segmental ventricular performance. All three coronary territories are represented in this view, making it useful for detecting acute ischemia.. Transgastric Long-Axis View. The transgastric long-axis view is also useful, as the left ventricular apex is imaged most readily in this plane. This is especially important when isolated abnormalities confined to the apex are sought by TEE. This view is also useful in measuring cardiac output through continuous wave Doppler interrogation of the aortic valve. Estimations of cardiac output with this ...
Health care stakeholders need to invest in value-based care, innovative care delivery models, advanced digital technologies. XploreMR will help you to know declarative, procedural, contextual, and somatic information about the "Intraoperative Imaging Market". It also provides a critical assessment of the performance of emerging and mature markets in a new publication titled "Global Market Study on Intraoperative Imaging: Systems Segment Projected to Grow at a Relatively High CAGR over the Forecast Period".. XploreMR examines the performance of the global intraoperative imaging market for a period of eight years in a new report titled "Intraoperative Imaging Market: Global Industry Analysis and Forecast, 2016-2024." According to the report, companies operating in the global intraoperative imaging market are mainly focusing on geographic expansion, establishing facilities in proximity to target markets and consolidation of existing manufacturing capabilities to gain larger market share.. Click ...
Mediastinum aims to provide high level evidence and useful resources for all healthcare professionals engaged in delivering quality care to their mediastinal patients.
[118 Pages Report] Check for Discount on Global Intraoperative Computed Tomography (CT) Sales Market Report 2017 report by QYResearch Group. In this report, the global Intraoperative Computed Tomography (CT) market...
Vaidya, J. S., Wenz, F., Bulsara, M., Tobias, J. S., Joseph, D., Keshtgar, M., Flyger, H., Massarut, S., Alvarado, M., Saunders, C., Eiermann, W., Metaxas, M., Sperk, E., Sutterlin, M., Brown, D., Esserman, L., Roncadin, M., Thompson, A., Dewar, J. A., Holtveg, H., Pigorsch, S., Falzon, M., Harris, E., Matthews, A., Brew-Graves, C., Potyka, I., Corica, T., Williams, N. R., & Baum, M. (2013). Updated results of local control and first analysis of survival from the randomised trial of risk-adapted TARGeted Intraoperative radioTherapy (TARGIT-A) for early breast cancer. Lancet, In press. ...
At Cole Eye Institute, surgeons and researchers are working to develop the next generation of intraoperative OCT devices and instrumentation to improve ophthalmic surgical outcomes in real time.
Intraoperative neurophysiological monitoring is a procedure to continuously monitor the nervous systems functional integrity during operations involving the brain and spinal cord. Electrodes or needles attached to the patients relevant anatomy continuously transmit information, which can be viewed on a monitor.
[161 Pages Report] Intraoperative Imaging Market categorizes the global market By Product (CT, MRI, Ultrasound), By Application (ENT, Gastro) & By Geography
DI-fusion, le Dépôt institutionnel numérique de lULB, est loutil de référencementde la production scientifique de lULB.Linterface de recherche DI-fusion permet de consulter les publications des chercheurs de lULB et les thèses qui y ont été défendues.
TY - JOUR. T1 - Intraoperative radiation therapy for breast cancer patients. T2 - Current perspectives. AU - Dutta, Sunil W.. AU - Showalter, Shayna L.. AU - Showalter, Timothy N.. AU - Libby, Bruce. AU - Trifiletti, Daniel M.. PY - 2017/4/18. Y1 - 2017/4/18. N2 - Accelerated partial breast irradiation (APBI) provides an attractive alternative to whole breast irradiation (WBI) through normal tissue radiation exposure and reduced treatment duration. Intraoperative radiation therapy (IORT) is a form of APBI with the shortest time interval, as it delivers the entirety of a planned radiation course at the time of breast surgery. However, faster is not always better, and IORT has been met with healthy skepticism. Patients treated with IORT have an increased compliance and overall satisfaction when compared to patients treated with WBI. However, early randomized trial results demonstrated an increased rate of recurrence after IORT, slowing its widespread adoption. Despite these controversies, IORT ...
Intraoperative radiation therapy, or IORT, is the application of therapeutic levels of radiation to the tumor bed while the area is exposed during surgery. IORT is typically a component in the multidisciplinary treatment of locally advanced and recurrent cancer, in combination with external beam radiation, surgery and chemotherapy. As a growing trend in recent years, IORT can also be used in earlier stage cancers such as prostate and breast cancer. IORT was found to be useful and feasible in the multidisciplinary management of many solid tumors but further studies are needed to determine the benefit more precisely. Single-institution experiences have suggested a role of IORT e.g. in brain tumors and cerebral metastases, locally advanced and recurrent rectal cancer, skin cancer, retroperitoneal sarcoma, pancreatic cancer and selected gynaecologic and genitourinary malignancies. For local recurrences, irradiation with IORT is, besides brachytherapy, the only radiotherapeutic option if repeated ...
Touch spray mass spectrometry using medical swabs is an ambient ionization technique (ionization of unprocessed sample in the open air) that has potential intraoperative application in quickly ide ...
TY - JOUR. T1 - Intraoperative ultrasound in spinal tumor surgery. AU - Prada, Francesco. AU - Vetrano, Ignazio G.. AU - Filippini, Assunta. AU - Del Bene, Massimiliano. AU - Perin, Alessandro. AU - Casali, Cecilia. AU - Legnani, Federico. AU - Saini, Marco. AU - DiMeco, Francesco. PY - 2014. Y1 - 2014. N2 - Purpose: Intraoperative ultrasound (ioUS) has become increasingly widespread in brain tumor surgery but it is not yet a standard procedure in spinal surgery. We analyzed intraoperative ultrasonographic findings of different spinal tumors and their influence on the surgical strategy. Methods: We evaluated patients who underwent surgery for spinal tumor (extradural, intradural extramedullary, intradural intramedullary) removal, with ultrasound (US) guidance. Intraoperative standard B-mode images were acquired using a 3-11 MHz linear US probe. Before tumor removal the lesion was identified on the two axes and measured and defined as hyperechoic, isoechoic or hypoechoic. Other characteristics of ...
The report estimates that in 2017, nearly 1,275 units of 0.2T systems were sold across the global Intraoperative MRI Equipment Market. Towards the end of the forecast period, 0.2T systems are assessed to reflect a global market volume share of approximately 40%. On the other hand, 3.0T systems will showcase rapid volume growth at 9% CAGR over the forecast period. Increasing complexities in neurosurgeries will drive the demand for high-field intraoperative MRI equipment, and nearly 895 units of 3.0T systems will be adopted worldwide by the end of 2026.. Request for Sample of this Global Market Research Report Here - https://www.factmr.com/connectus/sample?flag=S&rep_id=519. High Demand for 0.2T Systems to Reflect the Growing Need for Low-field Intraoperative MRI Equipment. Detailed improvements in the images generated by 0.2T systems is driving their sales in the global market for intraoperative MRI equipment. Small read-out gradients are made visible and the 0.2T intraoperative MRI equipment ...
This book represents a head-to-toe guide for clinicians who are interested in applying real-time NIR imaging for their patients. Expert surgeons from around the globe share their experience with NIR imaging, most commonly performed using indocyanine green (ICG) fluorescence.
abstract from The Journal of Veterinary Internal Medicine.. The purpose of this retrospective study was to 1) describe the intraoperative appearance of various canine pathological spinal conditions, and 2) to investigate how intraoperative ultrasonography assisted in modification of surgical and postoperative treatment plans.. Twenty five dogs undergoing spinal surgery received intraoperative ultrasound examination. Presenting neurological signs included spinal pain, ataxia. paraparesis. paraplegia, tetraparesis and root signature. The surgical procedures included continuous dorsal laminectomies (10), hemilaminec-tomies (20). and one dorsal laminectomy. Final neurological diagnoses were Hansen type II discs (8), Hansen type I disc (7), caudal cervical vertebral instability and malformation (9), spinal cord neoplasia (astrocytoma in one dog and anaplastic neoplasia in another dog), discospondylitis (1), granulomatous meningoencephalitis (1) and a nerve sheath mass (1). There was one normal lumbar ...
Purpose: Although intraoperative radiotherapy (IORT) is known to be a method that can reduce local recurrence in locally advanced colorectal cancer, it is not widely used. The aim of this study was to report our experience with IORT for locally advanced rectal cancer. Methods: From 1991 to 1994, nine patients with locally advanced rectal cancer received IORT. External beam radiotherapy was given postoperatively in five patients and preoperatively in three. Seven patients received chemotherapy. IORT was done with 6-MeV or 9-MeV electrons, and 12 Gy was irradiated at the tumor bed. The median follow-up period was 84 months (range, 15 to 208 months). Results: The median age of patients was 51 years (range, 42 to 73 years). All patients had advanced clinical T-stage (cT3/4)cancer. The overall and the disease-free survival rates were 66.7% and 66.7% at 5 years, respectively. One patient developed a local recurrence near the anastomosis site, which was out of the IORT field. Four patients died before ...
Breast IORT is radiation treatment delivered as a single radiation dose at the time of breast conserving surgery (lumpectomy). IORT is a form of brachytherapy, where radiation is delivered within the surgical cavity.
Lifetime cost-effectiveness analysis reveals $630 million annual cost savings, less radiation exposure and better quality of life for patients.
Ellsmere, J., Kane, R. & Jones, D.B. Reply to: Re: Intraoperative ultrasonography during planned liver resections remains an important surgical tool ((2007) 21: 1280-1283). Surg Endosc 22, 1913 (2008). https://doi.org/10.1007/s00464-008-9942-8. Download ...
Currently available investigating modalities like CT scans, MRI etc although have a high accuracy in staging of gastrointestinal(GI) tract malignancies, are not correct in all cases . The aim of this study is to assess the role of intraoperative ultrasound as a modality to increase the staging accuracy of GI tract ...
immediate identification and evaluation of blood flows intraoperatively.. The essential and cost effective intraoperative microvascular instrument that provides you with the sound information you need.. The VTI 20 MHz Microvascular Doppler System was specifically designed for use by surgeons who have a need to interrogate the microvascular vessels. This audio blood flow detector allows for real-time, intraoperative assessment of vessels in a wide variety of surgical specialties.. The System is ideal for intraoperative use in neurosurgical procedures. Combining a miniature probe tip with a high operating frequency, the system emits a tightly focused signal with a shallow depth of signal penetration, imparting a level of precision essential for the neurosurgeon. The sterile- out-of-the-package, single-use probes - optimize patient safety and eliminate probe failure due to reprocessing. ...
Over the last 2 centuries, surgeons have depended on 2 tools in the operating room to detect disease-their eyes to look for suspicious masses and their hands to feel for abnormal tissue (23). Surgeons make subjective decisions based on experience of anatomical tissue planes and tumor spread in deciding where to excise tumors to obtain disease-free margins. However, this is historically inaccurate, especially in complex fields including those with prior radiation, infection, or trauma. For example, at University of Miami, one experienced urologist carried out 100 consecutive radical prostatectomies and recorded intraoperatively if he suspected the tumor margins were positive or negative based on visual clues and palpation (24). Despite his intraoperative decision that the surgical margins were negative in all 100 patients, the true pathologic margins were positive in 39% of cases. The intraoperative assessment of the margin status had a high false-negative rate and a sensitivity of only 7%. The ...
Critical Care Research and Practice is a peer-reviewed, Open Access journal that offers a forum for physicians and health professionals work in the area of health services research in critical care. The journal publishes original research articles, review articles, and clinical studies related to anesthesiology, perioperative and critical care medicine, as well as the integration of intraoperative management in preparation for postoperative critical care management and recovery.
Critical Care Research and Practice is a peer-reviewed, Open Access journal that offers a forum for physicians and health professionals work in the area of health services research in critical care. The journal publishes original research articles, review articles, and clinical studies related to anesthesiology, perioperative and critical care medicine, as well as the integration of intraoperative management in preparation for postoperative critical care management and recovery.
Touch spray mass spectrometry using medical swabs is an ambient ionization technique (ionization of unprocessed sample in the open air) that has potential intraoperative application in quickly identifying the disease state of tissue and in better characterizing the resection margin. To explore this potential, we studied 29 human brain tumor specimens and obtained evidence that this technique can provide diagnostic molecular information that is relevant to brain cancer. Touch spray using medical swabs involves the physical sampling of tissue using a medical swab on a spatial scale of a few mm(2) with subsequent ionization occurring directly from the swab tip upon addition of solvent and application of a high voltage ...
Intraoperative MRI Market analysis is provided for global market including development trends by regions, competitive analysis of the Intraoperative MRI ma
NASHUA, N.H.--(BUSINESS WIRE)--Feb 19, 2013--iCAD (Nasdaq: ICAD), an industry-leading provider of advanced image analysis, workflow solutions and radiation therapy for the early identification and treatment of cancer, today reported financial results for the three and twelve months ended December 31, 2012.. "During the fourth quarter we posted strong revenue growth, maintained adjusted EBITDA profitability and generated positive cash flow," said Ken Ferry, President and CEO of iCAD. "This considerable progress can be attributed to continued strong growth of our therapy solutions, a much stronger quarter in cancer detection coupled with on-going disciplined expense management. For the full year, therapy revenue was particularly strong as we more than doubled new systems and applicator sales compared with 2011." "We were pleased that the U.S. Centers for Medicare & Medicaid Services (CMS) issued an improved payment policy for the delivery of Intraoperative Radiation Therapy (IORT). The payment ...
Purpose This study was designed to evaluate the effect of preoperative pregabalin on intraoperative neurophysiological monitoring in adolescents undergoing surgery for spinal deformities.
OBJECTIVE: Postoperative delirium is a common complication in the elderly after surgery but few papers have reported after spinal surgery. We analyzed various risk factors for postoperative delirium after spine surgery. METHODS: Between May 2012 and September 2013, 70 patients over 60 years of age were examined. The patients were divided into two groups : Group A with delirium and Group B without delirium. Cognitive function was examined with the Mini-Mental State Examination-Korea (MMSE-K), Clinical Dementia Rating (CDR) and Global Deterioration Scale (GDS). Information was also obtained on the patients education level, underlying diseases, duration of hospital stay and laboratory findings. Intraoperative assessment included Bispectral index (BIS), type of surgery or anesthesia, blood pressure, fluid balance, estimated blood loss and duration of surgery. RESULTS: Postoperative delirium developed in 17 patients. The preoperative scores for the MMSE, CDR, and GDS in Group A were 19.1+/-5.4, ...
Advanced fluid optimization has been an increasing perioperative focus around the world. Initiatives to incorporate intraoperative fluid management (IOFM) and enhanced recovery after surgery (ERAS) protocols have highlighted the need for an accurate means of monitoring fluid and medication administration.. ...
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Cho, K.J., Vinik, A.I., Thompson, N.W., Schieids, J.J., Porter, D.J., Brady, T.M., Cadavid, G., Fajans, S.S.: Localization of the source of hyperinsulinism: Percutaneous transhepatic portal and pancreatic vein catheterization with hormone assay. Am. J. Roentgenol.139:237, ...
We included 19 studies (1756 participants). We selected only randomized, placebo-controlled, double-blinded studies to minimize inclusion of poor quality studies. However, the risk of bias in the included studies was not formally assessed. Children receiving a single intraoperative dose of dexamethasone (dose range = 0.15 to 1.0 mg/kg) were half as likely to vomit in the first 24 hours compared to children receiving placebo (risk ratio (RR) 0.49; 95% confidence interval (CI) 0.41 to 0.58; P , 0.00001). Routine use in five children would be expected to result in one less patient experiencing post-tonsillectomy emesis (risk difference (RD) -0.24; 95% CI -0.32 to -0.15; P , 0.00001). Children receiving dexamethasone were also more likely to advance to a soft/solid diet on post-tonsillectomy day one (RR 1.45; 95% CI 1.15 to 1.83; P = 0.001) than those receiving placebo. Finally, postoperative pain was improved in children receiving dexamethasone as measured by a visual analog scale (VAS, 0 to 10) ...
The intraoperative neurophysiological monitoring industry is now experiencing a period of rapid growth. This growth is majorly attributed to factors such as; rising number of spinal, cranial procedures, technological advancements, cost effectiveness, among others. The IONM techniques are widely adopted in developed countries, but due to low level of awareness, this technology is still in infancy in various developing nations. This can create opportunity for various market players to invest in such countries to achieve greater benefits.. Globally the market for intraoperative neurophysiological monitoring was valued at $1.1 billion and anticipated to grow at a CAGR of 8.9% from 2016-2027.. Get a Copy of Sample Report @ https://www.marketresearchfuture.com/sample_request/729 .. Intraoperative neurophysiologic monitoring (IONM) as the name suggests is a monitoring technique which refers to a group of procedures used during surgery to monitor neural pathways during high-risk neurosurgical, ...
Principal Investigator:FUJIWARA Takashi, Project Period (FY):1994 - 1995, Research Category:Grant-in-Aid for General Scientific Research (C), Research Field:Thoracic surgery
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Intraoperative cholangiogram (IOC) can define biliary ductal anatomy. Routine IOC has been proposed previously. However, current surgeon IOC utilization practice patterns and outcomes are unclear. Nat
When you get your gallbladder removed, your doctor might use a type of imaging called an intraoperative cholangiogram. WebMD explains what it is, how it can help, how its done, and what the risks are.
IMRIS Inc. has announced that University Hospital Tübingen neurosurgeons in Germany, are reporting success toward their objectives of limiting patient ris
CPT® 2012 revises intraoperative neurophysiologic monitoring code usage for surgery. By Gloria Galloway, MD, FAAN Use of intraoperative neurophysiologic
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