TY - JOUR. T1 - The effects of acute intraocular pressure elevation on rat retinal glutamate transport. AU - Holcombe, David J.. AU - Lengefeld, Nadia. AU - Gole, Glen A.. AU - Barnett, Nigel L.. PY - 2008/6/1. Y1 - 2008/6/1. N2 - Purpose: To investigate the relationship between intraocular pressure (IOP), retinal glutamate transport and retinal hypoxia during acute IOP elevations of varying magnitude. Methods: Female Dark Agouti rats were anaesthetized by ketamine/xylazine/ acepromazine (10/5/0.5 mg/kg i.p.). The anterior chamber was cannulated with a 30-gauge needle attached to a saline reservoir. The target IOP (20-120 mmHg, in 10 mmHg increments) was obtained by adjusting the reservoir height. After 10 mins of IOP stabilization, 2 μl of the non-endogenous glutamate transporter substrate, D-aspartate, was injected into the vitreous (final concentration 50 μm), and the elevated IOP maintained for a further 60 mins (total duration of IOP elevation was 70 mins). Glutamate transporter function ...
A study has been made of the time courses of the pupillary and intraocular pressure responses of conscious rabbits to clonidine administered either topically or intravenously. Topical unilateral application of clonidine caused transient pupil dilatation and a biphasic intraocular pressure response; an initial hypertensive response preceded a hypotensive phase lasting several hours. Pupillary and hypertensive responses were absent in the untreated eye, but there was a rapid decrease of intraocular pressure. Intravenous administration of clonidine caused an immediate and large decrease of intraocular pressure in both eyes. Phenoxybenzamine given intravenously inhibited the pupillary dilatation and the hypertensive responses to clonidine. The role of efferent adrenergic neuronal activity in mediating the local biphasic pressure response was studied in rabbits with unilateral precervical and postcervical sympathotomy. The results showed the hypotensive response to be dependent on an intact ...
TY - JOUR. T1 - Intraocular pressure elevation in uveitis. AU - Md. Din, Norshamsiah. AU - Mohd Isa, Hazlita. AU - Taylor, Simon R J. AU - Barton, Keith. AU - Lightman, Susan L.. PY - 2012/2. Y1 - 2012/2. N2 - Raised intraocular pressure in uveitis, either due to the disease itself or secondary to treatment with steroids, is one of the most common causes of secondary glaucoma in clinical practice. There are currently no standardized criteria for the diagnosis nor guidelines for the management of raised intraocular pressure in uveitis. Intraocular pressure elevation may be due to any combination of several mechanisms and, as a result, the prognosis differs from primary glaucomas. In addition, the management of ongoing inflammation without elevating the intraocular pressure remains a challenge. Ideally, new anti-inflammatory agents should have better anti-inflammatory properties with safer intraocular pressure profiles, while sustained release medications to lower intraocular pressure would ...
I would like to congratulate Theelen et al for their recent article on impact factors on intraocular pressure measurements in healthy subjects,1 and I would like to add a thought. As Theelen and colleagues point out with reference to the literature,2,3 increased pressure in the jugular vein leads to increased brain pressure, and by an increase in the episcleral venous pressure, to an elevation of intraocular pressure. Correspondingly, in a previous study by Teng and associates, it was discussed that a tight necktie may increase intraocular pressure by an increased jugular vein pressure and could affect the diagnosis and management of glaucoma.4 It may be taken into account, however, that the brain pressure and pressure in the cerebrospinal fluid space surrounding the retrobulbar part of the optic nerve are the counter-pressure against the intraocular pressure across the lamina cribrosa.5 If the cerebrospinal fluid space pressure is elevated (as a result of increased jugular vein pressure), the ...
Out of a total of 2272 diurnal curves (DC) of intraocular pressure (IOP) obtained from 1178 patients 690 first curves of the right eye of all patients were analysed. For each DC there were 4-6 IOP readings taken between 8 am and 6.30 pm of the same day. The patients diagnosis, age, sex, type of IOP lowering medication, diabetes, and the calendar month of the year were recorded. In 40% of cases the highest IOP was found at the earliest morning measurement with some 65% of peaks occurring before noon. The lowest IOP measurement showed no specific predilection for any particular time of the day. These findings were true for all diagnosis groups. The mean range of IOP fluctuation during the DC was 5.0 mm Hg in normals, 5.8 mm Hg in patients with open angle glaucoma (OAG), and 6.8 mm Hg in patients with ocular hypertension (OHT). Patients treated with timolol had a lower mean IOP fluctuation range than those on other types of IOP lowering treatment. No association was found between all other ...
Purpose: : To determine factors affecting intraocular pressure (IOP) and the need for glaucoma surgery in patients undergoing pars plana lensectomy and vitrectomy (PPL/V) for retained lens materials. Methods: : A retrospective chart review was conducted of patients who underwent PPL/V between 2000 and 2007. Patients with no history of cataract extraction (CE), follow-up of less than 30 days, or a recent history of severe globe trauma requiring PPL/V were excluded. Results: : We identified 118 consecutive patients, 64 males and 54 females, who were entered into the study. Mean age at the time of PPL/V was 69.7 ± 12 years (range 21 to 92 years) with a mean follow-up of 523 ± 512 days (range 32 to 2611 days). IOP increased following cataract extraction by a mean of 13.4 mmHg from a mean of 17.3 to a mean maximum IOP (Tmax) of 30.7 mm Hg (2-tailed t-test, p,0.0001), which then improved following PPL/V to a mean Tmax of 24.4 (2-tailed t-test, p , 0.0001). IOP continued to improve and by the last ...
Glaucoma, a progressive optic neuropathy due to retinal ganglion cell (RGC) degeneration, is one of the leading causes of irreversible blindness. Although glaucoma is often associated with elevated intraocular pressure (IOP), IOP elevation is not detected in a significant subset of glaucomas, such as normal tension glaucoma (NTG). Moreover, in some glaucoma patients, significant IOP reduction does not prevent progression of the disease. Thus, understanding IOP-independent mechanisms of RGC loss is important. Here, we show that mice deficient in the glutamate transporters GLAST or EAAC1 demonstrate spontaneous RGC and optic nerve degeneration without elevated IOP. In GLAST-deficient mice, the glutathione level in Müller glia was decreased; administration of glutamate receptor blocker prevented RGC loss. In EAAC1-deficient mice, RGCs were more vulnerable to oxidative stress. These findings suggest that glutamate transporters are necessary both to prevent excitotoxic retinal damage and to ...
Purpose To evaluate acute and chronic changes in optic nerve head (ONH) structures and intraocular pressure (IOP) in patients receiving intravitreal injections (IVIs) of anti-VEGF.
In recent years, one of the hot topics in glaucoma research has been the effect of IOP fluctuation on POAG. Although more and more studies have confirmed that a decrease in the mean IOP level can reduce the risk of developing POAG, the findings from major prospective clinical trials about the impact of IOP fluctuation on POAG remain controversial [25, 27-30]. In this paper, we analyzed the post-randomization IOPs from OHTS and EGPS taking a latent class analysis (LCA) approach. The LCA allows us to identify distinct patterns of IOP change over time and then associates the changes in IOP with the risk of POAG. The results from both studies showed that different patterns of IOP change could markedly affect the risk of POAG (irrespective of their baseline, pre-randomization IOP levels). In OHTS, the change in IOP was best described by 6 distinct patterns. The model identified a subset of participants in whom IOP variability also played an important role in predicting POAG. This subgroup showed the ...
This study investigated the effects of sugammadex versus neostigmine/atropine combination in patients for hemodynamic parameters and intraocular pressure during
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Glaucoma of the eye, which is often interpreted as elevated intraocular pressure, is a disease that is one of the leading causes of blindness in the world. This is a condition in which normal flow of aqueous water through the eye is disrupted, and then eye swells. This is what causes high levels of intraocular pressure within the eye, damaging the optic nerve at the same time and leads to the collapse of the visual field, and finally to loss of vision ...
Besides optic disc evaluation and visual field testing, the diagnosis of ocular hypertension, primary glaucoma and normal-tension glaucoma is based on an arbitrary IOP cutoff point of 21 mmHg [11]. This cutoff is made on the basis of statistical grounds, principally for screening purpose rather than as a diagnostic criterion. It is nevertheless in clinical use and any factor that changes the estimates of IOP can lead to a misclassification of the patient or predisposed individuals [12].. In this study it was found that the mean CCT and IOP among Ethiopian glaucoma patients were 508.07 μm and 19.46 mmHg respectively. This study also showed a statistically significant association between CCT and IOP. Furthermore, CCT was correlated linearly with IOP values (ρ =0.271, p , 0.001). In this study IOP was manipulated with surgery or medication in some, and not in others, and hence this result should be interpreted cautiously as correlation between baseline untreated IOPs and CCT is much more ...
TY - JOUR. T1 - Diurnal and 24-h Intraocular Pressures in Glaucoma. T2 - Monitoring Strategies and Impact on Prognosis and Treatment. AU - Konstas, Anastasios G.. AU - Kahook, Malik Y.. AU - Araie, Makoto. AU - Katsanos, Andreas. AU - Quaranta, Luciano. AU - Rossetti, Luca. AU - Holló, Gábor. AU - Detorakis, Efstathios T.. AU - Oddone, Francesco. AU - Mikropoulos, Dimitrios G.. AU - Dutton, Gordon N.. PY - 2018/11/1. Y1 - 2018/11/1. N2 - The present review casts a critical eye on intraocular pressure (IOP) monitoring and its value in current and future glaucoma care. Crucially, IOP is not fixed, but varies considerably during the 24-h cycle and between one visit and another. Consequently, a single IOP measurement during so-called office hours is insufficient to characterize the real IOP pathology of a patient with glaucoma. To date IOP remains the principal and only modifiable risk factor for the development and progression of glaucoma. Only by evaluating IOP characteristics (mean, peak and ...
October 10, 2017 - release at 7:30 am CET Sophia Antipolis, France and Watertown, Mass, United States. Nicox S.A. (Euronext Paris: FR0013018124, COX), the international ophthalmic company, and pSivida Corp, (NASDAQ:PSDV) (ASX:PVA), a leader in the development of sustained release drug products and technologies, today announced their entry into a collaboration agreement to explore the potential of combining Nicoxs nitric oxide (NO)-donating compounds with pSividas bioerodible sustained release drug delivery system, to develop a sustained release drug to lower intraocular pressure (IOP) in patients with glaucoma or ocular hypertension.. Nicox and pSivida will collaborate on the selection of NO-donating product candidates from Nicoxs research portfolio to combine with pSividas sustained release drug technology. pSivida will be responsible for initial development activities of ocular insert formulations, for which it will receive undisclosed sums by Nicox. The companies may then elect to proceed ...
A method of lowering intraocular pressure (IOP) employs an upregulating agent that induces increased prostaglandin synthesis in the eye. The method of treatment entails administering to the eye of a mammal in need thereof a prostaglandin upregulating agent to increase endogenous prostaglandin synthesis and thereby effect a reduction in intraocular pressure. In a preferred embodiment the upregulating agent is IL-1.
Press Release Nicox and pSivida Enter Strategic Collaboration Agreement to Develop Sustained Release Drug to Lower Intraocular Pressure in Patients with Glaucoma Focus will be on Combining Nicox's New
Glaucoma is a disease that affects the eyes. Characteristic of glaucoma is the increase intraocular pressure and damages the optic nerve. Glaucoma drops vision and can lead to complete blindness. If the vision was lost as a result of the disease (glaucoma), it is possible to help the patient it is impossible, as the optic nerve died. Those who have been already diagnosed with this condition, it is not necessary to wear sunglasses, drink atropine - since this can all raise the intraocular pressure.. Described below folk remedies of treatment of glaucoma be used only after consulting a doctor!. 1. In this disease it is necessary to do the rinsing infusion of anise. 1 tablespoon chopped herbs filled with 0.5 Cup of boiled water cost a few minutes. The warm liquid wash the eyes 3-4 times a day.. Here assistant can be and Shilajit: 0.15 to 0.2 grams (a piece as small seed) to chew, swallow and drink water. Take 2-3 times a day: morning on an empty stomach during the day-before food for 30 minutes and ...
The diagnosis of glaucoma has changed over the years. Historically, any intraocular pressure above 21 mmHg was considered to be the definition of glaucoma. Today, it is clear that an elevated intraocular pressure is just a risk factor for glaucoma. An elevated intraocular pressure may be seen in normal patients and a low intraocular pressure may be seen in glaucoma patients.. The Visual Field Test is currently the gold standard for evaluating the status and progression of glaucoma. It evaluates the peripheral vision by having patients respond each time they see a projected light in the peripheral visual field. Both the diagnosis and the evaluation of progression of glaucoma can be made with this test.. The OCT-HD Nerve Fiber Analysis is the latest technology for evaluating the status of the optic nerve. It directly measures the thickness of the nerve fiber layer emerging from the optic nerve. It is thought that this instrument may help to catch glaucoma years earlier, before vision loss actually ...
The effects of ethanol on intraocular pressure, blood pressure, and the BP/IOP ratio and a comparison of a semi-automated sphygmomanometer with a conventional sphygmomanometer
Elevated intraocular pressure (IOP) is the best recognized risk factor for the pathogenesis of glaucoma and the extent of retinal ganglion cell (RGC) degeneration in glaucoma is closely correlated with the extent of IOP elevation. Therefore, accurately and reliably measuring IOP is critical in investigating the mechanism of pressure-induced RGC damage in glaucoma. However, IOP is typically measured under general anesthesia in most studies using mouse models and many anesthetics affect the IOP measurements in both human and animals. Continue reading "Effect of General Anesthetics on IOP in Elevated IOP Mouse Model". ...
Helpful, trusted answers from doctors: Dr. Chang on can you tell me the relationship between inter ocular pressure and sugar level: Blood sugar can cause retinopathy (damage to the retina) and increased near sightedness but does not affect ocular pressure.
The term glaucoma, refers to a group of disorders that cause damage to the optic nerve of the eye. The optic nerve can be thought of as the connecting cable which links the eye to the brain. Once that cable or optic nerve is severely damaged, (and the damage is irreversible), blindness can result.. Glaucoma blinds an estimated 60,000 people each year worldwide. Over 3 million Americans carry the diagnosis of glaucoma and it is estimated that an additional 2-3 million Americans are at risk.. Screening for glaucoma consists of a comprehensive eye examination including intraocular pressure measurement, optic disc examination and visual field testing where indicated.. People at greatest risk to develop glaucoma include people over age 50 with elevated intraocular pressure, African-americans, and people with affected family members.. Treatment for glaucoma includes topical and oral medications, and laser and incisional surgery. The overwhelming majority of patients found to have glaucoma can be ...
My intraocular pressure is a little higher than average and my doctor- he is specialist of glaucoma- advise me to apply eye lotion to prevent from glaucoma, but recently Ive have some doubts about his...
The unit of measurement for intraocular pressure is millimeters of mercury (mmHg). For example, this unit measures blood pressure. A healthy intraocular pressure lies
TY - JOUR. T1 - Simultaneous management of blood flow and IOP in glaucoma. AU - Harris, Alon. AU - Jonescu-Cuypers, Christian. AU - Martin, Bruce. AU - Kagemann, Larry. AU - Zalish, Miriam. AU - Garzozi, Hannah J.. PY - 2001. Y1 - 2001. N2 - Factors other than intraocular pressure (IOP) elevation must be involved in initiation and progression of glaucoma. An additional element in disease causation may be ischemia in the retina and optic nerve head. Ischemic damage to neurons in the CNS is similar mechanistically and histopathologically to changes seen in glaucoma. Further, glaucoma patients with normal IOP show clear evidence for cerebral and ocular ischemia. Aging and atherosclerosis reduce the ability of the eye to autoregulate blood flow when ocular perfusion pressure changes: the dependence of blood flow on perfusion pressure links ischemia to IOP. Consequently, neuroprotective treatments for glaucoma should be designed to both reduce IOP and improve ocular nutrient delivery.. AB - Factors ...
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We found that ketamine did not significantly increase IOP in pediatric patients undergoing PSA. Although we saw a statistically significant trend in IOP during the study period, we do not believe that this finding is clinically significant given the small changes seen in IOP (,2.5 mm Hg). Small, transient elevations in IOP in this range are not even considered clinically significant for patients with glaucoma, as diurnal fluctuations of IOP to this degree are anticipated.15,16 These findings are important because ketamine has not been traditionally used in the PED for PSA for ophthalmic exams in pediatric patients with eye injuries due to concerns that ketamine might increase IOP. The strengths of our study include stratification by age to ensure the inclusion of younger children, a noninferiority design with sample size calculations, and dosage of ketamine typical for PSA usage in the PED (i.e., 1-2 mg/kg IV). In addition, we saw no evidence of a dose-response relationship between ketamine ...
For patients interested in avoiding the psychoactive effects of smoking cannabis, topical cannabinoid applications have also proven effective at decreasing ocular pressure. In one study, applying THC oil directly to the eyes of participants with high blood pressure resulted in the lowering of systolic blood pressure, which researchers concluded may lead to a decrease in intraocular pressure. In another, applying cannabinoid directly to the eye decreased intraocular pressure within the first 30 minutes with maximal reduction being reached in 60 minutes. One study that applied cannabinoids directly to the eyes of rabbits recorded decreased intraocular pressure within 1.5 hours of administration and the effects lasted for more than 6 hours. In addition, the eye to which the cannabinoid had not been administered also experienced a decrease in intraocular pressure, but the effect lasted for 4 hours ...
Target intraocular pressure is the level of pressure inside the eyes that a doctor sets for a person who has glaucoma or high eye pressure. The target pressure is based on the degree of optic nerve damage, the amount of visual field loss, and, to a lesser degree, the initial pressure in the eye and how widely it varies each time it is measured.. Treatment that keeps the pressure at or below the target level reduces the risk of damage to the optic nerve and may help slow the progression of glaucoma. A doctor uses a test called tonometry to monitor pressure in the eyes.. ...
We are excited to announce that the Ophthalmology Service recently purchased a novel device to treat glaucoma.. The equipment uses newly patented MicroPulse technology to deliver laser energy and lower intra-ocular pressure. Compared to previous laser units, the MicroPulse device provides a kinder, gentler approach with an improved efficacy and safety profile. While standard cyclophotocoagulation creates focal burns in the ciliary body, this novel device revolutionizes the procedure by "chopping" continuous laser waves into repetitive short pulses, thereby avoiding focal heating and burning of the tissue. This technique results in a slow, steady application of laser energy to the ciliary body.. The device can be used in dogs, cats and horses, and is a good option for patients for which medical therapy for glaucoma has become ineffective. It is also beneficial for patients with early disease as an adjunctive treatment for elevated intra-ocular pressure.. ...
When medicated eye drops and laser surgery do not remedy intraocular pressure (IOP), your doctor may recommend conventional glaucoma surgery. The most common surgical option is trabeculectomy, also called filtration surgery. During the procedure, your surgeon will create a tiny opening in the sclera (the white part of the eye) covered by a thin trapdoor. The excess aqueous humor (the clear fluid between your eyes lens and cornea) drains through the trapdoor to a small reservoir just under the eye surface, hidden by the eyelid. This will lower intraocular pressure and slow the effects of glaucoma.. About half of all trabeculectomy patients do not require glaucoma medication for a considerable amount of time after surgery. While effective at reducing IOP, this procedure is not considered a cure, and people can still experience vision loss even after surgery. Vision loss usually happens if the procedure fails which happens when your body heals too aggressively and closes the hole that the surgeon ...
With that in mind, there are several aspects of my own EHR software that I really appreciate over paper charts. Besides the fact that I can actually read what I wrote (or typed), one thing that I particularly enjoy is the fact that I am able to consistently look at a new patients optic nerves without knowing his or her intraocular pressure (IOP) values beforehand. ...
Question - Getting control of my Inta Ocular Pressure. Ask a Doctor about diagnosis, treatment and medication for Cracker injury, Ask an Ophthalmologist
Aug. 12, 2009. At A Glance. $1.5 million grant will advance vision research at UI. A four-year, $1.5 million grant from the National Eye Institute at the National Institutes of Health will help University of Iowa researchers study the cellular events that cause vision loss in glaucoma. The award was effective Aug. 1.. Led by Markus Kuehn, Ph.D., UI assistant professor of ophthalmology and visual sciences, the team will investigate the degeneration of retinal ganglion cells. The death of these cells leads to vision loss, but what initiates and specifically causes their death is not known.. Current glaucoma treatment aims to decrease intraocular pressure and does not target the cellular pathways that affect survival of retinal ganglion cells. By understanding and eventually acting on those pathways, vision loss possibly could be prevented.. *. JPEC, Small Business Center send businesses to business plan semi-finals. Three of the eight semi-finalists in this years John Pappajohn Iowa Business Plan ...
BioAssay record AID 224018 submitted by ChEMBL: Compound was evaluated for decrease in intraocular pressure (IOP) (mmHg) at 1 hour postdosing to New Zealand white rabbits with 2% solubility.
Our company goal is preventing blindness for the estimated 80 million people who will suffer from glaucoma by 2020.. Our product, under development, addresses an unmet need by rendering accessible a continuous measurement of the intraocular pressure.. The key benefits for the medical professional and the patient is to increase the quality and relevance of diagnostic and treatment of glaucoma. ...
(a) Intraocular pressure before (0) and after (1 and 2) beginning of the treatment with latanoprost; highly significant (p|0,01)reduction of IOP by approxima
Intraocular pressure (IOP) is the pressure inside your eyes. Normally, this is around 16 millimeters mercury|mmHg (2.1 pascal|kPa). Pressures greater th...
The convergence of glaucoma and chronic kidney disease in the same population means that hemodialysis could be an important factor in control of intraocular pressure ...
Explore the highs & lows of intraocular pressure with these images that show results of abnormal pressure in the canine and feline eye.
Increased axial length: Increased axial length in an infants eye can indicate glaucoma, and monitoring of axial length can be used to assess the stability of the disease. Axial length is determined with ultrasound on the anesthetized eye. A normal axial length in an infant is about 17 mm. Any eye with an axial length of 20 mm or more, asymmetry between the two eyes, or increasing myopia should prompt a thorough evaluation for glaucoma. The worsening myopia seen in pediatric glaucoma is due to this increased axial length and can be determined in a preverbal child by retinoscopy - the use of a streak of light and the patients red reflex to determine refractive error. Increased Intraocular Pressure: Intraocular pressure is measured by the ophthalmologist using a hand held tonometer after topical anesthetic is applied to the cornea. This is sometimes performed under anesthesia, as it is difficult to get accurate readings in the awake child. Care should be taken to check IOP promptly after ...
Travaprost is an opthalmic solution used in the treatment of elevated intraocular pressure in patients with open angle glaucoma or ocular hypertension who are intolerant of other intraocular pressure lowering medications.
during surgery-RL according to 4-2-1 4 ml/kg/hr for first 10 kg (=40ml/hr) then 2 ml/kg/hr for next 10 kg (=20ml/hr)then 1 ml/kg/hr for any kg over 20 kg of weight. This always gives 60ml/hr for first 20 kg then you add 1 ml/kg/hr for each kg over 20 kg.. After surgery (PACU):4-2-1 rule. After operation ward on the day of surgery 1,5 ml/kg/hr.Postoperative day 1:1,5 ml/kg/hr RL, oral fluids. Postoperative day 2:oral fluids and solid food according to surgical allowance. ...
Dr. Spaeth, testifying on behalf of the-government, is adamant on this point; mLowering [eye] pressure is the most important aspect of treatment now. In fact, it is the 9_i 7 validated method by which we know we c_n held ulaucoma. N I (emphasis added) _I/ As the American Academy of Opthamology report_-submitted as Exhibit 2 by government witness, Dro Robert Hepler states: [POAG] . . _ has no known c_e . . . it usually can be effectively treated by :_ phaz_aceutical agentsor surgery that decreases IOP (intraocular pressure) and prevents optic damage ..... _o date. the only clinically, effective men,hod of accomDlishin_this_is by low_l___, w (Emphasis added) o _-_-Ai Dro John Merritt concurs: _The reduction of ocular tensions is central to the effective medical control of glaucoma. All Waccepted _ drug and surgical therapies .J currently deemed to be effective in the treatment of glaucoma seek to reduce abnormally elevated intraocular pressures. The accepted standard of what constitutes ...
The eyeball needs to maintain a certain level of tension, or pressure, within the eye to keep it from collapsing. A series of canals within the eye...
I am a 40 years old man having glaucoma. I was put on Xalatan 10 months back because of |b|high intra-ocular pressure (IOP) of 26|/b|. My eye angle was found to be open, but the optical coherence tomograpghy (OCT), Heidelberg retina tomography (HRT), GDx nerve fibre analysis, visual fields including short-wavelength automated perimetry (SWAP) were found to be normal. Since I had taken nasal steroids off and on for the last few years, I was suspected to be steroid responder and Xalatan was stopped after 4 months. After that, my IOP ranged between 18 and 21 for the next three months. Last month I took vasoconstrictor nasal drops Otrivin and an anti histamine for 7 days. Now I am having diurnal variation in IOP between 18 and 24, within the same day. My cornea thickness is 560 micron. |ul||li|Could these drugs be the cause? |li|Is it normal diurnal variation? |li|Should I be again put on IOP reducing drops? |li|Is there any relation between IOP and physical exercise and blood pressure? |li|Is there
Self-measurement of IOP by glaucoma patients is feasible and acceptable, but it remains to be seen whether it is sufficiently accurate to guide clinical management, according to an observational study…
Endocyclophotocoagulation (ECP) was developed in 1992 and is a longstanding and proven MIGS laser procedure usually combined with cataract surgery to help reduce intraocular pressure. The procedure involves shrinking of the ciliary processes under direct visualization with the goal of decreasing the amount of intraocular fluid (aqueous humor) produced within your eye. Since glaucoma usually involves a drainage problem, reducing the amount of fluid being made helps with the intraocular pressure. ECP is performed after cataract surgery; a special probe is introduced into the eye through the same cataract incision. This probe has both a special camera as well fiberoptic cables that deliver the laser energy. Your surgeon will observe the internal structures of your eye on a TV monitor and will direct the laser energy to the ciliary processes under direct visualization. This procedure does not involve opening up the conjunctival tissues to access Schlemms canal. This is a major advantage of this ...