There may be an inflammatory component to pathologic pregnancies, as evidenced by a Th1-dominant profile in women whose pregnancies ended in spontaneous abortion.
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CCL4, CCL20, IFN-γ, IL-2, IL-4, IL-10, IL-16, IL-17A, IL-17F, IL-18, MIF, TNSF15, IL-1β, IL-1R, IL-6, IL-7, IL-7R, IL-8, IL-10R, IL-12p35, IL-12p40, IL-3, IL-15, IL-16, IL-21, IL-21R, IL-22, IL-17D, LITAF, NK-lysin, CD25, CD80, CD83, CD86, IFN-α, IFN-r, TGFB4, B-defensin8 ...
IL-12/IL-23 p40, eFluor 660, clone: C17.8, eBioscience™ 25μg; eFluor 660 IL-12/IL-23 p40, eFluor 660, clone: C17.8, eBioscience™ Primary Antibodies IgY...
有多种机制认为病毒感染与过敏性炎症相互作用,从而导致下呼吸道功能障碍、喘息和哮喘。首先,潜在的过敏性炎症可以直接增强气道对鼻病毒感染的反应性。此外,病毒感染可损害气道上皮的屏障功能,导致气道壁对气传过敏原的吸收增加和炎症反应增强,而潜在的过敏性炎症也可能导致病毒复制增强。值得注意的是,鼻病毒感染和变应原均可促进气道上皮细胞产生IL-33, IL-33是最近发现的一种先天细胞因子,可促进2型气道炎症和重塑。据报道,这种类固醇耐药途径在难以控制哮喘的儿童中上调。有趣的是,IL-33多聚物与中晚期发作的喘息有关,而中晚期发作的喘息与早期生活中的过敏反应密切相关。 另一种先天上皮细胞因子IL-25也由鼻病毒诱导,在过敏患者鼻病毒感染的情况下,IL-25可能加重过敏性气道炎症 ...
Инфламмасома - важный компонент нативного иммунитета. Она представляет собой макромолекулярный комплекс, включающий сенсорные элементы, адапторные белки и зимоген каспазы-1. Под действием продуктов распада тканей и патогенных микроорганизмов инфламмасома активируется и превращает про-IL-1b и про-IL-18 в активные интерлейкины. Активация инфламмасом отмечена при многих воспалительных заболеваниях и служит мишенью для терапевтических воздействий. В настоящем обзоре обсуждается вклад инфламмасом в патогенез социально-значимых заболеваний ...
货号产品说明规格方法学认证4300604Vialshaker(IKA Vibrax300rpm) 1pceRIAInstruments4300606Vialextraction insertforurinaryhGH1pceRIAInstrumentsKIC1261IL-6 96TIRMARUOKIC1
Looking for online definition of B cell stimulatory factor II in the Medical Dictionary? B cell stimulatory factor II explanation free. What is B cell stimulatory factor II? Meaning of B cell stimulatory factor II medical term. What does B cell stimulatory factor II mean?
B-cell growth factor 1, 12kDa, also known as BCGF1, is a human gene. B-cell growth factor is released by T lymphocytes after either lectin or antigen stimulation. It supports the clonal proliferation of B lymphocytes. Entrez Gene: BCGF1 B-cell growth factor 1, 12kDa. Kumar A, Vasquez A, Maizel AL, Sharma S (1991). Human BCGF-12kD functions as an autocrine growth factor in transformed B cells. European Cytokine Network. 1 (2): 109-13. PMID 1966378. Vazquez A, Mills S, Sharma S, Maizel AL (October 1988). Expression of CD23 antigen is not necessary for human 12-kDa B cell growth factor-mediated B cell proliferation. European Journal of Immunology. 18 (10): 1647-9. doi:10.1002/eji.1830181029. PMID 2973416. Mehta SR, Sandler RS, Ford RJ, Sharma S, Maizel AL (1986). Cellular interaction between B and T lymphocytes: enhanced release of B cell growth factor. Lymphokine Research. 5 (1): 49-57. PMID 3484798. Ennist DL, Greenblatt D, Coffman R, Sharma S, Maizel A, Howard M (November 1987). ...
This report describes the effects of B cell growth factor (BCGFII) and other lymphokines in the differentiation of normal and tumor B cells. We compared BCL1 tumor B cells, normal B cells giving rise to a polyclonal response without the intentional addition of antigen, and an antigen-driven, SRBC-specific response. BCL1 tumor B cells gave maximum PFC responses when partially purified BCGFII was added or when suboptimal doses of BCGFII were mixed with one of several putative terminal differentiation factors we call B cell differentiation factors BCDF. IFN-gamma was not active as any of these factors. Maximum polyclonal responses of B cells were seen when either IL 2 or BCGFII were mixed with BCDF. In contrast, SRBC-specific responses showed a strict requirement for IL 2, and BCGFII and BCDF synergized with IL 2 to give a maximum response. The involvement of BCGFII in all of these responses suggests that BCGFII acts as a growth factor for a population of B cells that has differentiated much of the ...
Monkey IFN-gamma - IL-10 FluoroSpot Kit (2-plate). The dual-color cytokine FluoroSpot assay is a modification of the Enzyme-Linked ImmunoSPOT (ELISPOT) assay and is designed to detect double cytokine-secreting T cells at the single cell level. The assay is based on the use of fluorescent- instead of enzymatic-labeled conjugates. Previous attempts to develop an immunoenzymatic dual-color ELISPOT assay were less successful because of problematic interpretation of mixed color spots. The dual-color FluoroSpot assay, however, provides good discrimination between single and double cytokine-secreting cells and is particularly suited to detect T cell subpopulations with a characteristic cytokine profile. The sensitivity of the assay lends itself to measure very low frequencies of cytokine-secreting T cells (1/300,000).
BULGULAR: Y ksek IL-10 d zeyleri pek ok k t prognostik zellikle, ok k sa ya am s resi ve lenfopeni ile ili kiliydi. Alb min a s ndan IL-10 ile negatif ili ki, IL-4 ile pozitif ili ki bulundu. Eozinofil ve IgE ile ilgili herhangi bir ili ki kurulamad . Baz hastalarda g zlenen artm IL-4 geri planda kalm Th2 yola aktivasyonunun bir ip ucu olabilir ...
IL-12/IL-23 p40, PerCP-Cyanine5.5, clone: C17.8, eBioscience™ 25μg; PerCP-Cyanine5.5 IL-12/IL-23 p40, PerCP-Cyanine5.5, clone: C17.8, eBioscience™...
Serological cytokine expression for IL-1β over the time course.IL-1β levels were detected at all the allocated time points with a significant difference betwe
摘 要:γδT细胞是一群异质细胞,人和小鼠不同组织部位的γδT细胞亚群表型多变、功能丰富。γδT细胞经过胸腺选择,形成IL-17+γδT细胞、IFN-γ+γδT细胞或IL-4+γδT细胞,它的分化受到很多因素的调控。γδT细胞是炎症介质IL-17的重要来源,IL-17+γδT细胞可以参与多种疾病的诱发和发展,如过敏、自身免疫性疾病,甚至恶性肿瘤。此外,它们也在宿主防御中发挥保护作用,防治传染病和诱导细胞毒性T淋巴细胞对癌症的反应。就IL-17+γδT细胞的发育、分化和调节机制以及在各种疾病中的作用进行综述 ...
Gentaur molecular products has all kinds of products like :search , GenWay \ IL-4 Human - IL-4; B-cell stimulatory factor 1; BSF-1; Lymphocyte stimulatory factor 1; IGG1 induction factor; B-cell IgG differentiation factor; B-cell growth factor 1 \ 10-271-82216 for more molecular products just contact us
TABLE-US-00002 TABLE 2 Relative expression of interferon-gamma from human NK cells, as determined by Taqman ® real time PCR. Relative Condition expression NK media only 1 1:625 IL-27 1 1:125 IL-27 1 1:25 IL-27 1 1:5 IL-27 1 100 ng/ml IL-27 1 IL-2 only (100 ng/ml) 320 IL-27 + 1:625 IL-2 120 IL-27 + 1:125 IL-2 240 IL-27 + 1:25 IL-2 340 IL-27 + 1:5 IL-2 310 IL-27 + IL-2 (100 ng/ml) 190 IL-12 only (100 ng/ml) 650 IL-27 + 1:625 IL-12 740 IL-27 + 1:125 IL-12 710 IL-27 + 1:25 IL-12 690 IL-27 + 1:5 IL-12 705 IL-27 + IL-12 (100 ng/ml) 820 IL-18 only 1 IL-27 + 1:625 IL-18 1 IL-27 + 1:125 IL-18 1 IL-27 + 1:25 IL-18 1 IL-27 + 1:5 IL-18 1 IL-27 + IL-18 (100 ng/ml) 1 IL-2 + IL-12 2800 IL-27 + 1:625 IL-2 + IL-12 1500 IL-27 + 1:125 IL-2 + IL-12 1600 IL-27 + 1:25 IL-2 + IL-12 1700 IL-27 + 1:5 IL-2 + IL-12 2600 IL-27 + IL-2 (100 ng/ml) + IL-12 2100 IL-2 + IL-18 500 IL-27 + 1:625 IL-2 + IL-18 300 IL-27 + 1:125 IL-2 + IL-18 300 IL-27 + 1:25 IL-2 + IL-18 600 IL-27 + 1:5 IL-2 + IL-18 500 IL-27 + IL-2 (100 ng/ml) + ...
b_ˈiː s_ˈɛ_l ɡ_ɹ_ˈəʊ_θ f_ˈa_k_t_ə w_ˈɒ_n], [bˈiː sˈɛl ɡɹˈə͡ʊθ fˈaktə wˈɒn], [bˈiː sˈɛl ɡɹˈə‍ʊθ fˈaktə wˈɒn] ...
In this report we describe the generation of mice deficient in IL-13Rα2 to define the role of this receptor chain in IL-13 responses. IL-13Rα2 may act to modulate the effects of IL-13 in vivo in various ways. IL-13Rα2 could enhance IL-13 activities by increasing the strength of IL-13 signaling or attenuate IL-13 effects by negative signaling or simply as a molecular decoy. Attenuating roles of IL-13Rα2 could explain the lack of evidence for IL-13 effects on T cells or an enhancing role could explain the effect of IL-13 effect on airways hyperreactivity and eosinophil survival distinct from IL-4.. Interestingly, we find that the absence of IL-13Rα2 correlates with nearly complete loss of serum IL-13 and an increase in tissue IL-13 in IL-13Rα2−/− mice. The lack of serum IL-13 cannot be explained by a lack of IL-13 production in IL-13Rα2−/− mice as IL-13 is present in tissues of IL-13Rα2−/− and is produced by activated IL-13Rα2−/− immune cells. Serum IL-13Rα2 may act as a ...
IL-25). A member of the IL-17 family of immunoregulatory cytokines (IL-17E; SF20, a homodimer of 177 aa subunits), produced by Th2 cells. It has a role in allergic inflammation by up-regulating IgG and IgE production, eosinophil levels, and inflammatory responses, through induction of IL-4, IL-5, and IL-13. ...
Interleukin-6 (IL-6), 0.5 mg. IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survival of certain B cells and T cells.
Interleukin-6 (IL-6), 0.5 mg. IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survival of certain B cells and T cells.
Description - NHP interleukin 17F (CANDF6, ML1; Gene ID: 708220) is a cross-linked homodimer, a prototypical biomarker for Th17 cells, and is closely related to IL 17A. IL-17A can pair with IL-17F to form a heterodimer of intermediate activity. IL-17F has greater affinity for IL-17RC receptor while IL-17A prefers IL-17RA, so some target-based differentiation is obtained when more than one of the possible three dimers is present. This cytokine is also found to inhibit the angiogenesis of endothelial cells and induce endothelial cells to produce IL-2, TGF-β, and MCP-1 ...
Determination of IL-1β, IL-6, TNF-α, MIP-1α, IL-10, TGF-β1 and FGFb levels in the cell-free supernatant obtained from monocytes from healthy subjects (CG, n
IL-23A/IL-23 P19 Proteins available through Novus Biologicals. Browse our IL-23A/IL-23 P19 Protein catalog backed by our Guarantee+.
多种适用的IL-4ELISA试剂盒,如Cat, 小鸡, Cow等。在antibodies-online.cn对比IL-4ELISA试剂盒,以便找到您需要的产品。
Looking for online definition of B-Cell Stimulatory Factor 1 in the Medical Dictionary? B-Cell Stimulatory Factor 1 explanation free. What is B-Cell Stimulatory Factor 1? Meaning of B-Cell Stimulatory Factor 1 medical term. What does B-Cell Stimulatory Factor 1 mean?
The property of 109 CD4+ T cell clones (TCC) to induce IgE synthesis in vitro in human B cells was compared with their ability to produce IL-2, IL-4, and IFN-gamma in their supernatants (SUP) after 24-h stimulation with PHA. A significant positive correlation was found between the property of TCC to induce or enhance spontaneous IgE synthesis and their ability to release IL-4. In contrast, there was an inverse relationship between the IgE helper activity of TCC and their ability to release IFN-gamma, whereas no statistical correlation between the property to induce IgE synthesis and to produce IL-2 was observed. The ability of PHA-SUP from 71 CD4+ TCC to induce IgE synthesis in B cells was also investigated. Twenty-nine SUP (all derived from TCC active on IgE synthesis) induced production of substantial amounts of IgE in target B cells. There was a correlation between the amount of IgE synthesized by B cells in response to these SUP and their IL-4 content. An even higher correlation was found ...
TY - JOUR. T1 - Prolonged survival of mice with glioma injected intracerebrally with double cytokine-secreting cells. AU - Lichtor, T.. AU - Glick, R. P.. AU - Kim, Tae Sung. AU - Hand, R.. AU - Cohen, E. P.. PY - 1995/12/1. Y1 - 1995/12/1. N2 - A novel approach toward the treatment of glioma was developed in a murine model. The genes for both interleukin-2 (IL-2) and interferon-γ (IFN-γ) were first transfected into a mouse fibroblast cell line that expresses defined major histocompatibility complex (MHC) determinants (H-2(k)). The double cytokine-secreting cells were then cotransplanted intracerebrally with the G1261 murine glioma cell line into syngeneic C57BL/6 mice (H-2b) whose cells differed at the MHC from the cellular immunogen. The results indicate that the survival of mice with glioma injected with the cytokine-secreting allogeneic cells was significantly prolonged, relative to the survival of mice receiving equivalent numbers of glioma cells alone. Using a standard 51Cr-release ...
The cytokine interleukin-22 (IL-22), which is a member of the IL-10 family, is produced exclusively by immune cells and activates signal transducer and activator of transcription 3 (STAT3) in nonimmune cells, such as hepatocytes, keratinocytes, and colonic epithelial cells, to drive various processes central to tissue homeostasis and immunosurveillance. Dysregulation of IL-22 signaling causes inflammatory diseases. IL-22 binding protein (IL-22BP; encoded by IL22RA2) is a soluble IL-22 receptor, which antagonizes IL-22 activity and has genetic associations with autoimmune diseases. Humans have three IL-22BP isoforms, IL-22BPi1 to IL-22BPi3, which are generated by alternative splicing; mice only have an IL-22BPi2 homolog. We showed that, although IL-22BPi3 had less inhibitory activity than IL-22BPi2, IL-22BPi3 was more abundant in various human tissues under homeostatic conditions. IL-22BPi2 was more effective than IL-22BPi3 at blocking the contribution of IL-22 to cooperative gene induction with ...
Utilizing Stem Cell Cytokines, The AnteAGE System is one of the most effective, and advanced treatments for reversing premature aging.
Interleukin 33 (IL-33) is a protein that in humans is encoded by the IL33 gene. Interleukin 33 is a member of the IL-1 family that potently drives production of T helper-2 (Th2)-associated cytokines (e.g., IL-4). IL33 is a ligand for ST2 (IL1RL1), an IL-1 family receptor that is highly expressed on Th2 cells, mast cells and group 2 innate lymphocytes. IL-33 is expressed by a wide variety of cell types, including fibroblasts, mast cells, dendritic cells, macrophages, osteoblasts, endothelial cells, and epithelial cells ...
IL-1 receptor antagonist, IL-1RA/ IL-1RN, was initially purified from medium conditioned by human monocytes. IL-1RA belongs to the IL-1 family of cytokines, which includes 11 members that include three subfamilies in addition to the IL-1RA: IL-1 subfamily (IL-1α, IL-1β, IL-33), L-18 subfamily (IL-18
Human CellExp IL-27, human recombinant protein, p28, IL30, IL-27, IL-27A, IL27p28, Interleukin-27, EBI3 validated in (PBV10859r-10), Abgent
當寄生蟲或蛋白質抗原(protein antigens(被APC呈現給naive CD4+ T cell3會促使naive CD4+ T cell增殖並分化成TH2 cells3TH2 cells則藉由分泌不同cytokines(IL-4 IL-5 IL-13(去調控各種免疫反應如下 ...
引用Abcams小鼠IL-6 ELISA试剂盒(Interleukin-6) (ab100713)的参考文献列表。为您列举引用本产品的发表文章,并提供信息包括论文文献数据库中的检索编号以便您搜寻文章
Receptors, Interleukin-4, Type I information including symptoms, causes, diseases, symptoms, treatments, and other medical and health issues.
Interleukins are naturally occurring proteins that help the bodys immune system. The different types of interleukins all serve to...
产品名称:HumanIL-5ELISAReady-SET-Go规格:10plates货号:88-7056-88厂商:eBioscience产品介绍:Alsoknownas:Interleukin-5ReactivityHumanSensitivity4pg/mLStandardCurveRange4-500pg/mLComponentsCaptureAntibody.Pre-titrated,pu
ಆರೋಗ್ಯದ ಸೂತ್ರದ ಕಲ್ಪನೆಗಳ ಪ್ರಕಾರ ಡೇವಿಡ್ ಪಿ.ಸ್ಟ್ರಾಚನ್ ಅವರ ಹೇಳಿಕೆಯಂತೆ ಅಲರ್ಜಿಗಳು ಕಾಯಿಲೆಗಳು ಅನಿಯಮಿತ ಮತ್ತು ಅಶಿಸ್ತಿನ ಆರೋಗ್ಯದ ನಿಯಮಗಳನ್ನು ಅನುಸರಿಸುವದರಿಂದ ಇದು ಉಲ್ಬಣಗೊಳ್ಳುವ ಸಾಧ್ಯತೆ ಇದೆ.ನಿರಪಾಯಕಾರಿ ಅಂಟಿಜೆನ್ ಗಳTH2 ನ ಕೃತಕ ರೋಗನಿರೋಧಕಗಳ ಮೂಲಕ ಅದರ ಪ್ರತಿಕ್ರಿಯೆಯನ್ನು ಸೂಸ್ಮವಾಗಿ ಗಮನಿಸಬಹುದು. ಹಲವಾರು ಬ್ಯಾಕ್ಟೀರಿಯಾ ಮತ್ತು ವೈರಸ್ ಗಳು ಉನ್ನತ ಮಟ್ಟದ TH1ರೋಗ ನಿರೋಧಕ ಜೊತೆಗೂಡಿ TH೨ ಔಷಧಿಯುಕ್ತ ನಿರೋಧಕದ ಪ್ರಮಾಣವನ್ನು ...
References for Abcams Recombinant Human Interleukin 34 protein (ab109933). Please let us know if you have used this product in your publication
Differentiation of naïve CD4+ T cells into the T helper type 1 (TH1) phenotype requires signaling by interleukin (IL)-12 through the IL-12 receptor β2 chain, and activation of the signal transducer and activator of transcription (STAT) 4. On the other hand, induction of the TH2 phenotype from naïve CD4+ T cells requires IL-4 binding of the functional IL-4 receptor and activation of STAT6. A concomitant reduction of IL-12Rβ2 is also observed. When naïve CD4+ T cells are treated simultaneously with both IL-4 and IL-12, the IL-4 effects predominate and TH2 cells develop. Thus, it has been hypothesized that IL-4-dependent decreases in IL-12Rβ2 expression prevent IL-12 signals, and this allows for differentiation into the TH2 phenotype. However, it is not known what effect constitutive expression of the IL-12Rβ2 chain has on the development of TH2 cells. Nishikomori et al. found that IL-12Rβ2 transgenic CD4+ T cells differentiated into TH2 cells in the presence of IL-4, or IL-4 and IL-12. ...
NEX232 Interleukin-1 (IL-1) refers to a group of three polypeptides (interleukin-1 alpha (IL-1α), interleukin-1 beta (IL-1β) and interleukin-1 receptor antagonist (IL-1Ra)), that play a central role in the regulation of immune and inflammatory responses.. IL-1β is a pro-inflammatory cytokine involved in immune defense against infection. ...
Description - Interleukin-27 (IL-27), a heterodimeric cytokine and a relatively new member of the IL-6/IL-12 family, plays an important role in the regulation of Th1 responses. IL-27 consists of two subunits, an EBV-transformed gene 3 (EBI3) subunit and a p28 cytokine subunit. IL-27 activity is mediated by binding to its receptor, IL-27R, comprised of WSX-1 and gp130. Several immune cells co-express both subunits of the IL-27 receptor. IL-27 is expressed by antigen-presenting cells upon antigen activation. IL-27 potently induces the proliferation of naive T cells, and synergistically with IL-12 stimulates the production of IFN-γ by naive CD4+ T cells ...
Bellevue Golds stage two feasibility at its namesake project in WA has revealed it is set to become one of the worlds top gold operations.
An interleukin-13 receptor subunit that is closely-related to the INTERLEUKIN-13 RECEPTOR ALPHA1 SUBUNIT. The receptor is found as a monomeric protein and has been considered to be a decoy receptor for interleukin-13 due the fact that it lacks cytoplasmic signaling domains.
Recombinant Interleukin-17F, IL-17F, Interleukin-24, IL-24, cytokine stimulates PBMC and T-cell proliferation, expressed in HEK293 cells
This phase I trial studies the side effects and best dose of pembrolizumab and recombinant interleukin-12 in treating patients with solid tumors. Monoclonal
HEK-Blue™ IL-17 cells allow the colorimetric detection of bioactive human and murine interleukin-17A (IL-17A), as well as human IL-17F and IL-17E (IL-25). They can be used for the screening of anti-IL-17 antibodies or for IL-17 cell-based potency assay.
When your immune system detects a threat, your white blood cells release interleukin-6. Once secreted, IL-6 triggers what is known as the inflammatory cascade.
人IL-17 ELISA试剂盒(Interleukin-17) ELISA试剂盒datasheet (ab100556).Abcam抗体、ELISA、激动剂拮抗剂、表观遗传试剂、蛋白多肽,使用效果保证,中国70%以上现货。
Interleukin 2 (IL-2) is a monomeric glycoprotein that is primarily produced by activated CD4+ T cells, CD8+ T cells and dendritic cells. It is characterized as a proinfla..
Combining with interleukin-10 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
Exclusive to Global Medical Discovery (new Significance Statement and new figure). Interleukin-1 deficiency prolongs ovarian lifespan in mice.
changes in frequency, activation state, and HIV-specific functional capacity of T and NK cells in blood, as monitored by expression of intracellular cytokines during the first 12 weeks after stopping HAART, with respect to termination of Step ...
产品名称:MouseIL-1aELISPOTReady-Set-Go规格:10plate货号:88-7813-88厂商:eBioscience产品介绍:Alsoknownas:Interleukin1a,IL1a,IL-1alpha,IL-1alphaReactivityMouseComponentsCaptureAntibody.Pre-titrated,FunctionalGrade(lowe
Mouse IL-17A standard, 0.3 µg, for use in AlphaLISA immunoassays. This vial contains enough analyte to run 10 standard curves. This standard is provided in the AlphaLISA mouse IL-17A kits, but can also be ordered separately.
TEL :. +86 153 6067 3248 (Intl). US Toll free: 855 777 3210 EU Toll free: 800 3272 9252 Korea Toll free: 001 800 3272 9252 (Telecom ...
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白血球介素或介白素(interleukin(是一組細胞因子(分泌的信號分子(》最早發現在白血球中表達作為細胞間信號傳遞的手段》實際上3白血球介素可以由多種細胞產生》免疫系統的功能3在很大程度上依賴於白細胞介素》一些罕見的白細胞介素缺陷不足都常出現自身免疫性疾病或免疫缺陷》 ...
High-quality IL-29 proteins from ACROBiosystems. Various species and tags of PCSK9 proteins. Minimal Batch-to-Batch Variation. Bulks in stock.
Analyze information about public health with the interactive quiz and printable worksheet. These tools will help you point out important details...