IP Indian Journal of Neurosciences-IJN-Print ISSN No:-2581-8236 Online ISSN No:-2581-916XArticle DOI No:-10.18231,Sciatic neuropathy following intramuscular injection: Clinical and electrophysiological findings-IP Innovative Publication Pvt Limited, Medical Journals Publication, Open Access Journals, Print Journals,I
This experiment was carried out on 123 Farahani ewes from a herd in Delijan city in Markazi province of Iran to determine the best short-term method for oestrus synchronization. Ewes were divided into five experimental groups randomly: group 1) use of controlled intervaginal drug release devices (CIDR) for 7 days with intramuscular (IM) injection of PGF2α on zero day and IM injection of 500 IU equine chorionic gonadotropin (eCG) at the time of CIDR removal; group 2) use of CIDR for 7 days and IM injection of PGF2α on the 6th day and IM injection of 500 IU eCG at the time of CIDR removal; group 3) use of intravaginal sponge for 7 days with IM injection of PGF2α on zero day and IM injection of 500 IU eCG at the time of sponge removal; group 4) use of intravaginal sponge for 7 days with IM injection of PGF2α on the 6th day and IM injection of 500 IU eCG at the time of sponge removal and group 5) control, without any treatment. Results showed that parturition percentage on expected date was almost
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In my anatomy class, we had to search online and answer what buttocks muscle is used for IM injections and why. I searched and came accross an article, and so I answered that it is the gluteus medius
Axosin (Ceftriaxone) is a board spectrum parenteral third generation cephalosporin antibiotic. The drug is highly resistant to bacterial beta-lactamase and has a good activity against many gram-positive and gram-negative aerobic and some anaerobic bacteria. It inhibits bacterial cell wall synthesis in a manner similar to that of penicillin. Axosin (Ceftriaxone) is indicated for the treatment of the following major infections when caused by susceptible organisms: 1.Renal & urinary tract infection; 2.Lower respiratory tract infection particularly pneumonia; 3.Gonococcal infection; 4.Skin, soft tissue, bone & joint infection; 5.Bacterial meningitis; 6.Serious bacterial infection e.g. septicemia; 7.ENT infection; 8.Infection in cancer patients; 9.Prevention of postoperative infection; 10.Pre-operative prophylaxis of infection associated with surgery; 11.Typhoid fever. It is available as 250 mg IM Injection, 500 mg IM Injection, 1g IM Injection, 250 mg IV Injection, 500 mg IV Injection, 1g IV ...
Axosin (Ceftriaxone) is a board spectrum parenteral third generation cephalosporin antibiotic. The drug is highly resistant to bacterial beta-lactamase and has a good activity against many gram-positive and gram-negative aerobic and some anaerobic bacteria. It inhibits bacterial cell wall synthesis in a manner similar to that of penicillin. Axosin (Ceftriaxone) is indicated for the treatment of the following major infections when caused by susceptible organisms: 1.Renal & urinary tract infection; 2.Lower respiratory tract infection particularly pneumonia; 3.Gonococcal infection; 4.Skin, soft tissue, bone & joint infection; 5.Bacterial meningitis; 6.Serious bacterial infection e.g. septicemia; 7.ENT infection; 8.Infection in cancer patients; 9.Prevention of postoperative infection; 10.Pre-operative prophylaxis of infection associated with surgery; 11.Typhoid fever. It is available as 250 mg IM Injection, 500 mg IM Injection, 1g IM Injection, 250 mg IV Injection, 500 mg IV Injection, 1g IV ...
TY - JOUR. T1 - Intramuscular delivery of a single chain antibody gene prevents brain Aβ deposition and cognitive impairment in a mouse model of Alzheimers disease. AU - Wang, Yan Jiang. AU - Gao, Chang. AU - Yang, Miao. AU - Liu, Xiao-Hong. AU - Sun, Annie. AU - Pollard, Anthony. AU - Dong, X. AU - Wu, Xiao-Bing. AU - Zhong, Jin Hua. AU - Zhou, Hua-Dong. AU - Zhou, Xin-Fu. PY - 2010/11. Y1 - 2010/11. N2 - Anti-beta-amyloid (Aβ) immunotherapy is effective in removing brain Aβ, but has shown to be associated with detrimental effects. We have demonstrated that Adeno-associated virus (AAV)-mediated delivery of an anti-Aβ single chain antibody (scFv) gene was effective in clearing brain Aβ without eliciting any inflammatory side effects in old APPSwe/PS1dE9 transgenic mice. In the present study, we tested the efficacy and safety of intramuscular delivery of the scFv gene in preventing brain Aβ deposition. The scFv gene was intramuscularly delivered to APPSwe/PS1dE9 transgenic mice at 3months ...
Phytonadione aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of active prothrombin (factor II), proconvertin (factor VII), plasma thromboplastin component (factor IX), and Stuart factor (factor X). The prothrombin test is sensitive to the levels of three of these four factors-II, VII, and X. Vitamin K is an essential cofactor for a microsomal enzyme that catalyzes the post-translational carboxylation of multiple, specific, peptide-bound glutamic acid residues in inactive hepatic precursors of factors II, VII, IX, and X. The resulting gamma-carboxyglutamic acid residues convert the precursors into active coagulation factors that are subsequently secreted by liver cells into the blood.. Phytonadione is readily absorbed following intramuscular administration. After absorption, phytonadione is initially concentrated in the liver, but the ...
Intramuscular injections offer improved treatment adherence, ease in monitoring of adverse effects, and multiple administration sites.
DNA vaccines expressing plasma membrane and secreted forms of the influenza and measles virus hemagglutinins (HAs) have been used to evaluate the effect of secretion on DNA-raised antibody responses. At low doses of DNA, the plasma membrane form of the influenza virus HA raised higher titers of antibody than the secreted form. The isotype of the DNA-raised antibodies depended on both the method of DNA delivery and the form of the expressed antigen. Following intramuscular injections, DNAs expressing membrane bound forms of the influenza and measles HAs raised predominantly IgG2a. By contrast, DNAs expressing the secreted from of the two HAs as well as another secreted protein, human growth hormone, raised predominantly IgG1. Gene gun delivery resulted in predominantly IgG1 antibody responses for both secreted and membrane bound forms of the hemagglutinins. The raising of predominantly IgG1 by i.m. delivery of the secreted form of the influenza hemagglutinin was IL-4 dependent suggesting that a T-helper
Thanks to all for the sweet messages, calls, texts and prayers for Brody & Kylee. Being up at 3:30am made for a lonnngg day, but all went well! Weve been told for a while now that Brody & Kylee, due to their Cerebral Palsy & hypertonia/dystonia (tight muscles), may be good candidates for Botox. Even with physical & occupational therapy, constraint therapy, orthotics and endless exercises and stretches, these two will likely have minor issues due to their CP for years to come. After visiting with their neurologist in December, he thought it would be good to give the Botox a shot.. "Following intramuscular injection, the neurotoxin causes a reversible neuromuscular blockade, creating both muscle weakness and a reduction in tone." We were told that basically the Botox will temporarily paralyze or weaken the nerve endings allowing more flexibility and allowing us to stretch their muscles more effectively. Brody received 8 injections, 4 in each leg. Because of his tone, Brody toes walks from time to ...
In the present study we demonstrated a therapeutic effect of dTNFR in CIA when expressed from plasmid DNA under the control of constitutive and regulated promoters. Importantly, the therapeutic effect was achieved when DNA was delivered after disease onset, and all of the components for regulated expression were combined in a single vector.. We confirmed in DBA/1 mice that electroporation increases transfection efficiency in vivo following intramuscular injection of plasmid DNA, with transgene expression detected beyond 4 weeks from pGTRTL. In agreement with other studies using mice, these observations indicate that there is long-term persistence of plasmid DNA [10], and expression of the transgene luciferase [10] and rtTA [23] encoded by the autoregulatory plasmid. Regulation from pGTRTL in vivo is comparable to in vitro function [19], as demonstrated by the 43-fold increase in luciferase expression induced by 2 weeks of doxycycline induction, and return to basal expression 3 days after removal ...
Section 1: reflects both combinations. Section 2: QRD formatted Section 4.2: QRD + addition of IM use and the statement "The vaccine should be administered subcutaneously in patients with severe thrombocytopenia or any coagulation disorder (see section 4.4)". Also added the statement "The vaccine should under no circumstances be injected intravascularly".. Section 4.4: addition of IM use + statement "This vaccine should be given subcutaneously to individuals with severe thrombocytopenia or any coagulation disorder, because these individuals may bleed following intramuscular injections". Also added "Immunisation should be postponed in individuals suffering from moderate to severe acute febrile illness or infection".. Section 4.6: aligned with the QRD format. Section 4.8: QRD format + frequency changes from not known to rare. Section 5.1: Clinical Efficacy and Data updated, addition of statement "The European Medicines Agency has waived the obligation to submit the results of studies with ZOSTAVAX ...
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Ceftriaxone should not be given to patients with a history of hypersensitivity to cephalosporin antibiotics. It is contraindicated in premature infants during the first 6 weeks of life. Its safety in human pregnancy has not been established. Ceftriaxone is contraindicated in neonates if they require (or are expected to require) treatment with calcium-containing IV solutions, including continuous calcium containing infusions such as parenteral nutrition because of the risk of precipitation of ceftriaxone-calcium ...
Hi! Ive been working at a dispensary in Saudi Arabia for quite some time now. We administer tons of IM medications (99.5% gluteal, .4% deltoid, .1% vastus lateralis). I have noticed that all of the
I also noticed that the Celebrate Nurses page is getting some views. I will add content there this week. Meanwhile, you can also add a comment on the FB Nursing Site Page about your thoughts, ideas, concerns etc. about Nurses Week. This usually sparks some discussion as so many nurses feel that Nurses Week is silly, pretentious, and they never have had any good experiences with it. Bring on the discussion ...
The beef industry continues to make progress at reducing injection site lesions in the top sirloin. The latest "Top Sirloin Injection-Site Audit" showed an incidence rate of scars and lesions of 5.61%. The survey conducted in July of this year found the lowest rate of injection site damage in the top sirloin since the surveys began in March of 1991. The July survey sampled over 11,000 top sirloins. The study indicated that the average trim loss per lesion was 4.87 ounces. The survey found 7 (or 0.06%) fluid filled lesions. Though the survey indicates that the industry is making progress at solving the injection site problem, it also indicates that some producers are either not getting the word or are simply being irresponsible. Work at Colorado State University seems to make it obvious that intramuscular injections cause muscle and hence, beef damage. The message from industry leadership has been clear. When the product to be injected can be given either subcutaneously or intramuscularly, choice ...
BACKGROUND:Cabotegravir (CAB) is a novel strand-transfer integrase inhibitor being developed for HIV treatment and prevention. CAB is formulated both as an immediate-release oral tablet for daily administration and as a long-acting injectable suspension (long-acting CAB [CAB LA]) for intramuscular (IM) administration, which delivers prolonged plasma exposure to the drug after IM injection. HIV Prevention Trials Network study 077 (HPTN 077) evaluated the safety, tolerability, and pharmacokinetics of CAB LA in HIV-uninfected males and females at 8 sites in Brazil, Malawi, South Africa, and the United States. METHODS AND FINDINGS:HPTN 077 was a double-blind, placebo-controlled phase 2a trial. Healthy individuals age 18-65 years at low HIV risk were randomized (3:1) to receive CAB or placebo (PBO). In the initial oral phase, participants received 1 daily oral tablet (CAB or PBO) for 4 weeks. Those without safety concerns in the oral phase continued and received injections in the injection phase ...
Intramuscular injections are injections administered into a muscle. These injections are absorbed more quickly than subcutaneous injections because of the greater blood supply to the muscles. A 90-degree angle is used for injection. Aspiration is done to confirm that the needle is not in a blood vessel.This blog will cover many of the factors involved in these injections.. ...
Associations of Vitamin D with Inter- and Intra-Muscular Adipose Tissue and Insulin Resistance in Women with and without Polycystic Ovary Syndrome ...
A Phase I Open-label Dose-escalation Study to Evaluate the Safety of Intramuscular Injections of PLX-R18 Cells in Subjects with Incomplete Hematopoietic Recovery Following Hematopoietic Cell ...
Injecting intramuscularly is a difficult thing to learn and it takes a lot of practice. This instructional medical how to video guides your through the step by step process of giving an intramuscular injection. Watch and read along. It is important to wash your hands before handling any injection material.
Objective: To study the clinical pharmacokinetics of parecoxib sodium via intravenous and intramuscular injections in Chinese populations. Methods: A..
... to a patient who has suffered a fracture in his left arm. Which of the following situations
... PINE BROOK N.J. July 31 2013 /PRNewswire/...(Logo: a href http://photos.prnewswire.com/prnh/20090420/NY01624LOGO...Two of the studies assessed IM administration of ETI-204 following cha... These three recent studies demonstrate promising results of ETI-204 w...,Elusys,Releases,New,Data,On,Anthrax,Anti-Toxin,Administered,Via,Intramuscular,Injection,From,Three,Recent,Animal,Studies,biological,advanced biology technology,biology laboratory technology,biology device technology,latest biology technology
Certain medications, such as insulin, can only be administered by injection. Depending on the formulation and the type of medication, injectable medications can be given by several routes. They can be given through direct injection into a vein (known as intravenous, or IV injection), injection into a muscle (known as intramuscular, or IM injection), or injection directly under the skin - a procedure known as subcutaneous (SC orSQ) injection. It is very important that you understand how your pets injectable medication needs to be given; for example, if you accidentally give a medication intravenously instead of subcutaneously, complications can result. Most injectable medications given at home are intended to be given subcutaneously.. Read More ...
Certain medications, such as insulin, can only be administered by injection. Depending on the formulation and the type of medication, injectable medications can be given by several routes. They can be given through direct injection into a vein (known as intravenous, or IV injection), injection into a muscle (known as intramuscular, or IM injection), or injection directly under the skin - a procedure known as subcutaneous (SC orSQ) injection. It is very important that you understand how your pets injectable medication needs to be given; for example, if you accidentally give a medication intravenously instead of subcutaneously, complications can result. Most injectable medications given at home are intended to be given subcutaneously.. Read More ...
There is no reason why you cant attach the peptide to a protein carrier such as KLH or ovalbumin to increase the immunogenicity. Yes, you will get antibodies to the protein as well, but you need to make sure your screening assays are specific for the peptide, you should be okay. Another suggestion, try hamsters instead of rats. DNA is also an option, although the gene gun approach seems to be more successful than im injections of DNA. -ned Daniele Focosi ,mi at interhealth.info, wrote in message news:e794ccc8.0209111128.5ddb060b at posting.google.com... , I would like to suggest you to prove DNA immunization for better , results. Anyway please note Im just a PhD student and I have not real , experience with such a technique apart from literature results ! , Please let me know. , Best regards. , , Daniele , , news.dk.uu.net ,myd at nordicbioscience.com, wrote in message news:,3d78af5a$0$10685$4d4eb98e at news.dk.uu.net,... , , Dear all, , , , , I would like to know if it is possible to ...
1. Proper timing of serum sampling is critical. The trough sample should be obtained 30 minutes prior to the dose. Measure the peak level 15 to 30 minutes after completion of the IV infusion to avoid the distributive phase. Measure the peak level 90 minutes after an IM injection. Drawing the peak too soon will result in inaccurate analysis. Drawing at exactly the right time is not as important as having the lab note the exact times that the samples were drawn. Also, have the nurse note the exact times that the sample infusion was started and when it ended. Please be aware of the widespread policy of nursing personnel to record a dose as having been given exactly as ordered if it is given within 30 minutes of the recorded time. This will lead to significant errors in analysis, have everyone record the exact times. This issue cannot be stressed enough. Inaccurate recording of drug administration times and lab draw times are the greatest source of calculation error, having a greater effect than ...
...but hubby has gotten really good at giving those big old honkin injections. See? My last miserable pregnancy had an upside. It means that he can give IM injections with the best of them and hardly flinch at all. What a trouper. I am fortunate, indeed, and very spoiled, since the prospect of ever having…
Ultrasound Failures On occasion, our females can seem to proceed perfectly as planned, spitting-off the male like clockwork until we come to wheeling in the computer. Then we see nothing to support our theory that we have a pregnancy. No liquid filled uterus, no evidence of a fetus. Sometimes this is down to what is called a retained corpus luteum (retained CL). If the follicle fails to regress following a lack of fertilization or subsequent absorption of a newly formed embryo then progesterone continues to be produced. We have a phantom pregnancy. Our girl mistakenly thinks she is pregnant and continues to refuse the amorous advances of our stud. We blindly continue with our spit-offs until it is ultrasound time. Fortunately this happens only rarely and there is a solution. Drug time again. Estrumate is a synthetic prostaglandin that causes regression of the CL. Administered as a single 1ml IM injection it will allow return to normal receptivity. Do not administer however if there is doubt as ...
Immunoglobulins - Normal and Specific can be given by IV or IM injection to confer passive (temporary) immunity. Read more about Immunoglobulins - Normal and Specific
Ive been meaning to post the costs of the vitamin shots at the naturopathic college so that people could have that info. When you go to the clinic, you can see a doctor (for a higher cost) or a student with a supervising doctor present (for a lower cost). I, of course, chose the latter. For the initial visit, with the shot, the cost was $99. For follow-up visits, with the shot, the cost is $25. Not cheap, but not horrible. They very kindly offered to send me home with a months worth of shots at a time, provided I could get someone to do it for me, which would save me all but a monthly trip and cut office visit costs completely (the shot alone costs $11 each). However, I do not fancy being the pincushion for my husbands learning efforts at giving IM injections, especially as he is nearly as squeamish as I am around needles, LOL! So I am sticking with the higher cost and letting the professionals do the work. (Additionally, I enjoy the trip. Its nice to be able to tune out and just drive ...
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echocardiogram-used to assess heart valves. valve disorders require prophylactic antibiotics before invasive procedures. avoid IM injections when susp
Results for QLV parameters A, B, and τ2, and typical stress relaxation curve fits for IM and EX. A was significantly decreased in injured groups relative to CTL. A was significantly increased in the IM group compared to the EX and CA groups. B was significantly decreased in injured groups relative to CTL. B was significantly increased in the IM group compared to the EX and CA groups. τ2 was significantly decreased in the CA and EX groups relative to CTL. τ2 was significantly increased in the IM group compared to the EX groups. The IM group had a higher peak stress, and maintained this stress for a longer period of time, than the EX group. (Mean +/− standard deviation, *: significant difference relative to CTL [p,0.05], # significant difference due to activity level [p,0.05 ...
Vitamin B 12 - Cyanocobalamin. Vitamin B12 with B complex. Methlyation support injection with methylcobalamin, B6, B2 and folate. Adrenal support injections - combination of vitamins to enhance weak adrenals. Lipotrophic mix - combination of B vitamins, choline and methionine to help metabolize fats and assist with weight loss and detoxification. Gerovital - buffered procaine based on the work of Hungarian doctor, Ana Aslan, M.D.. AMP - adenosine monophosphate, the energy source in the cell, for muscle pain, fatigue and rapid recovery. European live cell extracts - personalized extracts for a regenerative program. Homeopathic injections - individualized based on your health conditions. ...
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
The following are the basic steps to follow. They will be explained in more detail in the next sections. Get the supplies Wash your hands Prepare medicine vial Identify correct dosage of medication Draw up medication Choose your site Prepare skin Insert needle Inject medication Withdraw needle Dispose of equipment Record
This is a Multicenter, double-blind, randomized, placebo-controlled, parallel-group comparative study to confirm the efficacy and safety of BOTOX 20 units single injection for the Chinese patients with glabellar lines. The subjects will receive a single intramuscular treatment consisting of 5 injections of either BOTOX? 20U or placebo ...
Hi.. Can anybody suggest me that 90772 and J0735 can be billed together. 90772 states subcutaneous or intramuscular administration of injection but cl
The FDA recently approved ZYPREXA RELPREVV (olanzapine) for Extended-Release Injectable Suspension for the treatment of schizophrenia in adults. The product is a long-acting intramuscular injection that sustains the delivery of olanzapine for up to 4 weeks. ZYPREXA RELPREVV is intended for deep intramuscular gluteal injection only. Dosages may include the following: 150 mg/2 weeks, 210 mg/2 weeks, 300 mg/2 weeks, 300 mg/4 weeks, or 405 mg/4 weeks. Note that 2 ZYPREXA RELPREVV intramuscular formulations exist with different dosing schedules. ZYPREXA IntraMuscular (10 mg/vial) is a short-acting formulation and should not be confused with ZYPREXA RELPREVV ...
TY - JOUR. T1 - Body fluid concentrations of ampicillin trihydrate in 6 horses after a single intramuscular dose.. AU - Brown, M. P.. AU - Stover, Susan M. AU - Kelly, R. H.. AU - Farver, Thomas B. PY - 1982/1. Y1 - 1982/1. N2 - Six adult mares were given a single dose of ampicillin trihydrate (250 mg/ml) intramuscularly at a dosage of 20 mg/kg body weight. Serum, synovial fluid, peritoneal fluid and urine ampicillin concentrations were measured serially over a 48 h period. The mean peak serum ampicillin concentration was 2.49 micrograms/ml at 6 h. Ampicillin was found in synovial fluid and peritoneal fluid, which obtained mean peak ampicillin concentrations of 1.65 micrograms/ml and 1.81 micrograms/ml at 6 h and 4 h respectively. These concentrations declined in parallel with serum concentrations and were still detectable at 48 h. Urine concentration of ampicillin was relatively high, with a mean peak concentration of 1364.9 micrograms/ml at 4 h.. AB - Six adult mares were given a single dose ...
TY - JOUR. T1 - Suppression of intracranial human glioma growth after intramuscular administration of an adeno-associated viral vector expressing angiostatin. AU - Ma, Hsin I.. AU - Guo, Ping. AU - Li, Juan. AU - Lin, Shinn Zong. AU - Chiang, Yung Hsiao. AU - Xiao, Xiao. AU - Cheng, Shi Yuan. PY - 2002/2/1. Y1 - 2002/2/1. N2 - Despite various therapeutic interventions, glioblastoma multiforme (GBM) is one of the most highly vascularized neoplasms in humans with poor prognosis. In this study, we show that a single i.m. injection of an adeno-associated viral (AAV) vector expressing angiostatin, a potent angiogenic inhibitor, effectively suppresses human glioma growth in the brain of nude mice. Approximately 40% of the tumor-bearing mice treated with AAV-angiostatin vector survived for ,10 months (the duration of the experiments). In contrast, 100% of the tumor-bearing mice in the control groups, with or without i.m. injection of a control vector AAV-GFP, died because of excessive tumor burden by 6 ...
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The study assessed the safety and efficacy of Pluristem Therapeutics PLX-R18 following intramuscular injection into irradiated and non-irradiated NHPs.
Reconstitute powder with 4 mL SWI or NS to a final concentration of 2,500 IU/mL. For IM injection, Trissel recommends reconstitution with 2 mL NS to give a final concentration of 5,000 IU/mL. For IM injections of high dose therapy (10,000 IU), the 10,000 IU vial can be reconstituted with 0.5 mL of NS to give a final concentration of 20,000 IU/mL. If ,2mL solution is need, prepare in 2 syringes for injection into 2 different sites. To avoid foaming, rotate gently; do not shake ...