The feasibility of operating with natural circulation as the normal mode of core cooling has been successfully demonstrated for a few small sized nuclear reactors. Natural circulation is being considered for cooling the core of a nuclear reactor under normal operating conditions in several advanced reactor concepts being developed today.. Although studies have been conducted in natural circulation for many decades, using natural circulation as the primary cooling mechanism for nuclear reactors or as a passive safety system requires a comprehensive understanding of local and integral system phenomena, validated benchmark data, accurate predictive tools, and reliability analysis methods. As full-scale experiments of supercritical water are expensive, scaling laws can be applied to develop test matrices using modelling fluids to reproduce similar conditions in a scaled-down experimental thermalhydraulic loop.. The main aim of this work is to understand the natural circulation phenomena by analyzing ...
The present thesis reports computer simulation studies of several phase transition related phenomena in a range of soft-condensed matter systems. A coherent unifying theme of the thesis is the understanding of dynamics of phase transitions through free energy calculations using recently developed efficient non-Boltzmann sampling methods. Based on the system/phenomena of interest, the thesis has been classified into four major parts: I. Isotropic-nematic (IN) phase transition in liquid crystals. II. Nucleation phenomena in gas-liquid transition with particular emphasis on the systems close to the spinodal curve. III. Collapse transition in linear hydrocarbon (n-alkane) chains for a varying range of length, solvent and temperature. IV. Crystallization of unbranched polymer chains in dilute solution, with particular emphasis on the temperature dependent crossover between the rod-like crystalline state and spherical molten globule state. The thesis has been further divided into ten chapters running ...
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CiteSeerX - Scientific documents that cite the following paper: Asymptotic intervals for indirect effects in structural equations models.
Human genome-wide transEDIT-dual CRISPR library (TransOMIC) developed using the Croatan algorithm (Erard et al., 2017). In pCLIP-Dual-SFFV-ZsGreen vector, expresses 2 gRNAs targeting the same gene. The collection includes an average of 3 vectors/gene. ...
Ncf2 - Ncf2 (untagged) - Mouse neutrophil cytosolic factor 2 (Ncf2), (10ug) available for purchase from OriGene - Your Gene Company.
Stata 12 has just been announced. The software will start shipping by the end of July. A key new feature introduced in the new version is the module for
To understand regulatory systems, it would be useful to uniformly determine how different components contribute to the expression of all other genes. We therefore monitored mRNA expression genome-wide, for individual deletions of one-quarter of yeast genes, focusing on (putative) regulators. The resulting genetic perturbation signatures reflect many different properties. These include the architecture of protein complexes and pathways, identification of expression changes compatible with viability, and the varying responsiveness to genetic perturbation. The data are assembled into a genetic perturbation network that shows different connectivities for different classes of regulators. Four feed-forward loop (FFL) types are overrepresented, including incoherent type 2 FFLs that likely represent feedback. Systematic transcription factor classification shows a surprisingly high abundance of gene-specific repressors, suggesting that yeast chromatin is not as generally restrictive to transcription as ...
RRH: Rural and Remote Health. Published article number: 1248 - A structural equation model of the determinants of malnutrition among children in rural Kelantan, Malaysia
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A Structural Equation Model of the Determinants of Health Care in the Surveyed Households in Rural Area of Dharwad District, Karnataka State, India,2012;2(3):245- ...
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How to interpret the nature of biological processes, which, when perturbed, cause certain phenotypes, such as human disease, is a major challenge. The completion of sequencing of many model organisms has made reverse genetic approaches [1] efficient and comprehensive ways to identify causal genes for a given phenotype under investigation. For instance, genome-wide knockout strains are now available for Saccharomyces cerevisiae [2, 3], and diverse high throughput RNA interference knockdown experiments have been performed, or are under development, for higher organisms, including C. elegans [4], D. melanogaster [5] and mammals [6, 7].. Compared to the direct genotype-phenotype correlation observed in the above experiments, what is less obvious is how genetic perturbation leads to the change of phenotypes in the complex of biological systems. That is, we might perceive the cell or organism as a dynamic system composed of interacting functional modules that are defined as discrete entities whose ...
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A helper function for htcIdentifyStep, creates an identifier function based on its given parameters. This created identifier function will identify the directed edges from targets to node.
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Biological systems use a variety of mechanisms to maintain their functions in the face of environmental and genetic perturbations. Increasing evidence suggests that, among their roles as posttranscriptional repressors of gene expression, microRNAs (miRNAs) help to confer robustness to biological pro …
Complete information for NCF1 gene (Protein Coding), Neutrophil Cytosolic Factor 1, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium
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