TY - JOUR. T1 - The impact of left ventricular hypertrophy on survival in candidates for liver transplantation. AU - Batra, Sachin. AU - Machicao, Victor I.. AU - Bynon, John S.. AU - Mehta, Shivang. AU - Tanikella, Rajasekhar. AU - Krowka, Michael J.. AU - Zacks, Steven. AU - Trotter, James. AU - Roberts, Kari E.. AU - Brown, Robert S.. AU - Kawut, Steven M.. AU - Fallon, Michael B.. PY - 2014/6. Y1 - 2014/6. N2 - Left ventricular hypertrophy (LVH) occurs in 12% to 30% of patients with cirrhosis; however, its prognostic significance is not well studied. We assessed the association of LVH with survival in patients undergoing a liver transplantation (LT) evaluation. We performed a multicenter cohort study of patients undergoing an evaluation for LT. LVH was defined with transthoracic echocardiography. The outcome of interest was all-cause mortality. LVH was present in 138 of 485 patients (28%). Patients with LVH were older, more likely to be male and African American, and were more likely to have ...
Semantic Scholar extracted view of Effect of left ventricular hypertrophy on myocardial blood flow and ventricular performance in systemic hypertension. by Allen B. Nichols et al.
Of the 3250 patients, 634 sufferers without visual impairment were matched with 634 individuals with visual impairment. In the propensity score-matched evaluation, patients with visual impairment had a significantly higher threat of all-cause mortality compared with individuals without visual impairment in crude model (HR 1.72, 95 CI, 1.21?.45, P ?0.003), model 1 (HR 1.71, 95 CI, 1.21?.44, P ?0.003) and model two (HR 1.69, 95 CI, 1.12?.54, P ?0.01) even soon after adjusting for sex, DM, cardiovascular disease, health insurance, education, duration of dialysis, the use of ACEi or ARB, left ventricular hypertrophy on electrocardiogram, serum creatinine, serum albumin, and HbA1c.Subgroup Analysis of All-Cause Mortality by Risk Variables According to Visual ImpairmentSubgroup analysis associations involving visual impairment and all-cause mortality in many subgroups of individuals are displayed in Figure two. In subgroup analyses, there have been no substantial interactions amongst visual impairment ...
Lu Z, Xu X, Hu X, Zhu G, Zhang P, Deel EVD, French JP, Fassett JT, Oury TD, Bache RJ, et al. Extracellular superoxide dismutase deficiency exacerbates pressure overload-induced left ventricular hypertrophy and dysfunction. Hypertension [Internet]. 2008;(1):19-25.
Left ventricular hypertrophy is enlargement and thickening (hypertrophy) of the walls of your hearts main pumping chamber (left ventricle).. Left ventricular hypertrophy can develop in response to some factor - such as high blood pressure or a heart condition - that causes the left ventricle to work harder. As the workload increases, the muscle tissue in the chamber wall thickens, and sometimes the size of the chamber itself also increases. The enlarged heart muscle loses elasticity and eventually may fail to pump with as much force as needed.. Left ventricular hypertrophy is more common in people who have uncontrolled high blood pressure. But no matter what your blood pressure is, developing left ventricular hypertrophy puts you at higher risk for a heart attack and stroke.. Treating high blood pressure can help ease your symptoms and may reverse left ventricular hypertrophy.. Left ventricular hypertrophy usually develops gradually. You may experience no signs or symptoms, especially during ...
Horizontal plane projections of vectorcardiograms registered by the Frank lead system were analyzed in 36 patients with left ventricular hypertrophy and in 24 with left ventricular hypertrophy and associated anterior wall infarction. All were studied at autopsy. The 0.01-, 0.02-, 0.03-second, and maximum QRS vectors were compared with similar measurements in 60 control subjects previously reported. New criteria for the vector-cardiographic diagnosis of left ventricular hypertrophy have been outlined. Close agreement with earlier reported groups of patients with anteroseptal and anterolateral infarction was found, and findings by others in patients with left ventricular hypertrophy were confirmed.. The direction of the 0.02-second QRS vector allowed the separation of the infarct group from the left ventricular hypertrophy group and from the normal, whereas the direction of the 0.03-second and maximum QRS vectors separated left ventricular hypertrophy from the normal. The magnitude of the maximum ...
The prevalence of and risk factors associated with echocardiographically determined left ventricular hypertrophy were examined in 4976 participants in the Framingham Heart Study (age, 17 to 90 years). Left ventricular hypertrophy was detected in 356 men (16%) and 513 women (19%). Prevalence increases dramatically with age (P , 0.001), with 33% of men and 49% of women age 70 or older affected. A significant association between blood pressure and left ventricular hypertrophy is present and occurs at levels of systolic pressure below 140 mm Hg (age adjusted, P , 0.001). There is a ninefold (women) to tenfold (men) increase from leanest to most obese group (age adjusted, P , 0.001). In multivariate analysis, age, blood pressure, obesity, valve disease, and myocardial infarction are independently associated in both sexes. We conclude that left ventricular hypertrophy is a common echocardiographic finding for which several risk factors can be identified. These findings support weight reduction and ...
The majority of LEOPARD patients have left ventricular hypertrophy, which may be accompanied by left ventricular outflow tract obstruction, and the risk of sudden cardiac death may be higher in this group. Careful risk assessment is therefore indicated. It has been suggested to use the same algorithms as for familial hypertrophic cardiomyopathy, but careful consideration is needed as it is unknown if the pathophysiological background of these 2 diseases are comparable (3).. Conclusion: LEOPARD syndrome is a rare genetic disease, which should be considered in patients with structural heart disease - in particular left ventricular hypertrophy - and widespread lentigenes. The diagnosis is based on clinical examination and genetic testing. Cascade clinical screening of relatives is recommended. The prognosis is mostly benign in the absence of left ventricular hypertrophy. In patients with left ventricular hypertrophy, risk stratification is recommended using the same algorithms as in hypertrophic ...
These results demonstrate that a small proportion (8%) of children and adolescents with essential hypertension already have LV mass index ,51 g/m2.7. The cutpoint of 51 g/m2.7 has previously been shown to be associated with a fourfold increase in risk for cardiovascular disease in adults.8 An additional 6% had LV mass between the 99th percentile and the cutpoint; therefore, 14% of the patients had severe LV hypertrophy. In addition, 17% of the patients were found to have concentric LV hypertrophy. This is a geometric pattern that has been associated with increased cardiovascular morbidity in adults.17 It is possible that these young patients with severe LV hypertrophy and abnormal LV geometry are on a course for early cardiovascular morbidity and mortality. This study was cross-sectional, so it is not possible to determine the extent to which patients crossed percentiles over time. However, the known relationship of elevated blood pressure with LV mass and the fact that 55% of the study ...
Adrenergic beta-Antagonists/*therapeutic use, Aged, Aged; 80 and over, Angiotensin II Type 1 Receptor Blockers/*therapeutic use, Antihypertensive Agents/therapeutic use, Atenolol/*therapeutic use, Blood Pressure/drug effects, Double-Blind Method, Female, Follow-Up Studies, Heart Rate/drug effects, Heart Ventricles/drug effects/pathology/ultrasonography, Humans, Hypertension/*complications/drug therapy, Hypertrophy; Left Ventricular/*drug therapy/etiology/ultrasonography, Losartan/*therapeutic use, Male, Middle Aged, Organ Size, Prospective Studies, Treatment Outcome ...
Objectives. The purpose of this study was to test the hypothesis that the longer duration of ventricular action potentials in hypertrophied hearts predisposes to the development of early after-depolarizations and triggered ventricular tachyarrhythmias.. Background. For unknown reasons, the incidence of sudden death is greater in patients with myocardial hypertrophy.. Methods. We measured left ventricular monophasic action potentials in normal dogs and dogs with left ventricular hypertrophy before and after administration of the calcium agonist BAY K 8644 and the potassium channel blocker cesium.. Results. We demonstraieo longer action potential durations in dogs with than in those without left ventricular hypertrophy. Also, BAY K 8644 produced phase 2 early afterdepolarizations and ventricular tachyarrhythmias more frequently in the dogs with than in those without left ventricular hypertrophy. Phenylephrine, an alpha agonist, further increased the action potential duration in hypertrophied ...
On the other hand, ECG-LVH according to the Cornell criteria has been found to be positively related to obesity, consistent with the known relationship of anatomic LVH to obesity [2,6,8]. In contrast, ECG-LVH according to the Sokolow-Lyon criteria has been found to be negatively associated with obesity in hypertensive patients as previously described in the literature. This suggests that the Sokolow-Lyon criteria identifies ECG-LVH in which obesity does not play a significant role in the genesis of hypertrophy and, in addition, reflects the negative influence of obesity on precordial voltage amplitudes in hypertensives and subsequent a lower sensitivity of the Sokolow-Lyon criteria for LVH in obese patients [1,6]. In this study, to increase the sensitivity for detecting ECG-LVH, both the Cornell and the Sokolow-Lyon criteria were accepted for defining ECG-LVH, because the Cornell criteria have been shown to be less dependent on body status also in the Korean population [11]. However, of the ...
Background The Swedish irbesartan left ventricular hypertrophy investigation versus atenolol (SILVHIA). Objective Angiotensin II induces myocardial hypertrophy. We hypothesized that blockade of angiotensin II subtype 1 (AT1) receptors by the AT1-receptor antagonist irbesartan would reduce left ventricular mass (as measured by echocardiography) more than conventional treatment with a beta blocker. Design and methods This double-blind study randomized 115 hypertensive men and women with left ventricular hypertrophy to receive either irbesartan 150 mg q.d. or atenolol 50 mg q.d. for 48 weeks. If diastolic blood pressure remained above 90 mmHg, doses were doubled, and additional medications (hydrochlorothiazide and felodipine) were prescribed as needed. Echocardiography was performed at weeks 0, 12, 24 and 48. Results Baseline mean blood pressure was 162/104 mmHg, and mean left ventricular mass index was 157 g/m2 for men and 133 g/m2 for women. Systolic and diastolic blood pressure reductions were ...
Toda la información sobre las últimas publicaciones científicas de la Clínica Universidad de Navarra. Usefulness of plasma cardiotrophin-1 in assessment of left ventricular hypertrophy regression in hypertensive patients
Studies that have examined the cardiopulmonary receptor control of circulation in hypertension have produced conflicting results. In 10 normotensive subjects and in age-matched essential hypertensive subjects without (n = 10) or with left ventricular hypertrophy (n = 12), as well as in seven subjects of the latter group restudied after 1 year of treatment that induced regression of cardiac hypertrophy, we examined the cardiopulmonary reflex by increasing central venous pressure and stimulating cardiopulmonary receptors through passive leg raising and by reducing central venous pressure and deactivating cardiopulmonary receptors through nonhypotensive lower body negative pressure. Reflex responses were measured as changes in forearm vascular resistance (mean blood pressure divided by plethysmographically measured blood flow), plasma norepinephrine concentration, and plasma renin activity. In hypertensive subjects without left ventricular hypertrophy, stimulation and deactivation of ...
Results 34.6% of evaluated children were obese. 26.8% of examined children had LVH (LVMI ,38.6 g/m2.7), 4.1% had significant LVH (LVMI ,51 g/m2.7). LVH was found in 40.7% obese children with AH (37% eccentric LVH, 3.7% concentric LVH, 3.7% concentric LV remodeling), in 11.1% LVH significant. In non-obese children LVH was detected in 21.4% (15.7% eccentric LVH, 5.7% concentric LVH, 8.6% concentric LV remodeling), significant LVH - in 1.4%. ...
This study provides further evidence that echocardiographically measured LV mass predicts adverse outcomes from hypertension. Age and echocardiographic LV hypertrophy independently predicted subsequent cardiovascular events. There were limitations to the study design and execution that may have influenced the results. First, the patients age range was wide, and the duration of hypertension at entry was variable, producing a rather diverse cohort. Second, the cohort consisted of volunteers for research studies and may not be representative of general populations. Third, patient and physician reporting of morbidity and causes of death may have been influenced by the knowledge of echocardiographic abnormalities. Fourth, the collection of outcome data was not preplanned and it is not stated how much of the telephone data was backed up by documentation from records. Does echocardiography add prognostic information to that provided by readily available and less expensive diagnostic methods? LV mass ...
In hypertensives, left ventricular hypertrophy predicts increased cardiovascular morbidity and mortality. Adding to this burden is abnormality of left ventricular (LV) geometry. Knowledge of the left ventricular geometric patterns in our newly diagnosed hypertensives may have some prognostic significance. One hundred (100) newly diagnosed hypertensives (61males and 39 females) and 78 normotensives (46 males and 32 females) were recruited for the study. All were clinically evaluated and an echocardiographic examination performed. Mean ages for the study subjects and controls were 51.40 ±11.60 and 51.50 ±11.50 years respectively (P = 0.47). Only 24% of the hypertensives had normal geometry with 76% being abnormal. Normal geometry was found in 63% of the controls with 37% being abnormal. Statistical significance was noticed when the geometric patterns of the hypertensive and controls were compared (p value < 0.001). This study showed that only 24% of our hypertensives had normal LV
Introduction 24-hour ambulatory blood pressure (BP) monitoring is a well-validated tool that can reveal the patients nocturnal dipping pattern. However, to the best of our knowledge, the role of home BP monitoring in identifying nocturnal dipping has not been studied. Methods We evaluated the nocturnal BP of 30 treatment-naive subjects using a home BP monitoring device. BP measurements were taken once during the daytime and once at night (three hours after sleep) by a blinded observer. Readings were correlated with left ventricular mass index. Results Night BP measurements were significantly lower in subjects without left ventricular hypertrophy (LVH) as compared to those with LVH, while the daytime readings were not significantly different between the two. The mean dips in nocturnal systolic and diastolic BP were 1.92% ± 6.89% and −0.55% ± 14.31%, respectively, in subjects with LVH. The corresponding values were 12.96% ± 6.16% and 11.36% ± 11.90% in those without LVH. The correlation ...
Having risk factors at least two of: age ≥45 years in male or ≥55 years in female, elevated blood pressure (systolic blood pressure ≥130 mmHg or diastolic blood pressure ≥85 mmHg, or treatment of previously diagnosed hypertension), high-density lipoprotein (HDL)-cholesterol ,40 mg/dL, family history of coronary artery disease at age ,55 years in male or ,65 years in female, central obesity (waist circumference ≥90 cm for male or ≥80 cm for female), fasting plasma glucose ≥110 mg/dL, or left ventricular hypertrophy on ...
A study was made of the incidence of cerebrovascular disease, the chronological trends, and the relationship between the disease types and risk factors in 16,491 citizens of Hiroshima and Nagasaki. The subjects underwent medical examination at least once between 1958-74, and were free of cerebrovascular disease at the initial examination. During the 16-year period, 1.162 cases of cerebrovascular disease developed in the study population, with diagnosis definite in 621. By type, there were 108 cases of cerebral hemorrhage, 469 cases of cerebral infarction, 33 cases of subarachnoid hemorrhage, and 11 cases of other unclassifiable types. As a risk factor of cerebral hemorrhage, elevation of systolic and diastolic blood pressure was the most closely related to onset, and left ventricular hypertrophy on electrocardiogram (ECG), and proteinuria were also related. However, a tendency was seen for the risk to be higher when the levels of serum cholesterol were lower. In cerebral infarction, aging like ...
BACKGROUND: Obesity is linked to increased left ventricular mass, an independent predictor of mortality. As a result of this, understanding the determinants of left ventricular mass in the setting of obesity has both therapeutic and prognostic implications. Using cardiovascular magnetic resonance our goal was to elucidate the main predictors of left ventricular mass in severely obese subjects free of additional cardiovascular risk factors. METHODS: 38 obese (BMI 37.8 +/- 6.9 kg/m2) and 16 normal weight controls subjects, (BMI 21.7 +/- 1.8 kg/m2), all without cardiovascular risk factors, underwent cardiovascular magnetic resonance imaging to assess left ventricular mass, left ventricular volumes and visceral fat mass. Left ventricular mass was then compared to serum and anthropometric markers of obesity linked to left ventricular mass, i.e. height, age, blood pressure, total fat mass, visceral fat mass, lean mass, serum leptin and fasting insulin level. RESULTS: As expected, obesity was associated with
Bijoy K. Kundu, PhD, is an Associate Professor in the tenure track in the department of Radiology and Medical Imaging at the University of Virginia, Charlottesville. After completing his PhD in Nuclear Physics from the Bhabha Atomic Research Center, India, he pursued his post-doctoral work at the Indian Institute of Technology, Kanpur, India. He then moved to the Department of Radiology, University of Virginia, as a post-doctoral associate and moved up the faculty ranks. Dr. Kundu is a member of many scientific societies and reviewer of a number of peer-reviewed journals. The goals of his lab are to develop and optimize quantitative cardiac PET imaging techniques to address the hypothesis of metabolic remodeling in small animal models of myocardial injury and type 2 diabetes. His lab is currently funded by a grant from the National Institutes of Health ...
The presence of left ventricular hypertrophy (LVH) as a treatable entity is of particular importance in patients with primary hypertension. Because LVH is associated with a strong risk of adverse clinical events (eg, heart failure, ischemic events, and cardiovascular death) and because evidence from retrospective studies suggests that regression of LVH, along with a decrease in blood pressure, may help modify these outcomes, the use of antihypertensive agents that have been shown to promote regression of LVH has been recommended. These include diuretics, beta-blockers (except those with intrinsic sympathomimetic activity ), angiotensin-converting enzyme (ACE) inhibitors, calcium channel blockers, peripheral alpha(1)-blockers, and central alpha(2)-stimulators. Agents to be avoided include direct arterial vasodilators (eg, hydralazine and minoxidil), which have strong sympathetic stimulating properties and tend to maintain LVH despite lowering blood pressure. The use of ACE inhibitors is increasing.
Left ventricular hypertrophy (LVH) has been reported to produce differential electrophysiological effects in isolated epicardial and endocardial cells. This study aimed to examine regional electrophysiological effects of LVH in normal and ischaemic conditions in the whole heart. LVH was secondary to perinephritis-induced hypertension. Monophasic action potential duration (MAPD(90)), effective refractory period (ERP) and conduction delay were measured in paced, isolated working rabbit hearts either at one right ventricular and two left ventricular sites (apical and basal epicardium) or at three left ventricular sites (apical and basal epicardium, apical: endocardium). The hearts were subjected to 30 min of regional ischaemia and 15 min of reperfusion. In non-ischaemic conditions, LVH produced uniform prolongation of MAPD(90) and ERP in the left ventricular epicardium, but not in the endocardium. After coronary artery occlusion, LVH significantly increased ischaemia-induced transepicardial ...
Narita, M.; Kurihara, T.; Murano, K.; Usami, M.; Honda, M.; Kanao, K., 1984: Effects of nifedipine on left ventricular systolic and diastolic functions in left ventricular hypertrophy
Thesis, English, Comparative study of functional chnges of left ventricular hypertrophy in athletes and hypertensive patients by means of doppler tissue imaging of the myocardium for El Kamary ، Summer Said
Essential hypertension complicated with left ventricular hypertrophy is a serious and perilous disease in the cardiovascular medicine. It is one of the main causes of heart failure and myocardial infarction.
TY - JOUR. T1 - Allopurinol Reduces both Left Ventricular Hypertrophy and Endothelial Dysfunction in Chronic Kidney Disease Patients. AU - Kao, Michelle. AU - Ang, D. S.. AU - Gandy, S. J.. AU - Houston, G.. AU - Lang, Chim. AU - Struthers, Allan. PY - 2010/8. Y1 - 2010/8. M3 - Book/Film/Article review. VL - 55. SP - 46. EP - 46. JO - Scottish Medical Journal. JF - Scottish Medical Journal. SN - 0036-9330. IS - 3. ER - ...
BACKGROUND: Although left ventricular hypertrophy (LVH) is a strong predictor of mortality in patients with end-stage renal disease, few studies are available before the start of dialysis treatment. The purpose of this study is to evaluate the preval
medwireNews: The prevalence of left ventricular hypertrophy (LVH) is increased in normoxemic patients with chronic obstructive pulmonary disease
Left Ventricular Hypertrophy Inhibition, Normalization of the Contractile Response and Oxidative Stress in Experimental Hypertension
54 Downregulation Erb2 and Erb4 receptors in patients with congestive cardiomyopathy and in patients with pressure overload hypertrophy due to aortic stenosis is related to diastolic load. Delrue, L.; Bartunek, J.; Goethals, M.; De Bruyne, B.; De Beenhouwer, H.; Vanderheyden, M. // European Journal of Heart Failure. Supplements;Jun2004, Vol. 3 Issue 1, p12 An abstract of the study "Downregulation Erb2 and Erb4 Receptors in Patients With Congestive Cardiomyopathy and in Patients With Pressure Overload Hypertrophy Due to Aortic Stenosis Is Related to Diastolic Load," by L. Delrue and colleagues is presented. ...
Background: Common conditions such as obesity and hypertension result in hemodynamic alterations that will induce remodeling of the left ventricle (LV). However, differences between the genders in the relationship of hemodynamics to LV geometry are not well known. The present study aims to investigate differences between the genders in this respect, in a sample of elderly persons. Methods: Echocardiography and Doppler was performed in a population-based sample aged 70 - The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study (n = 922). Hemodynamic patterns obtained by echocardiography and Doppler were evaluated in relation to four LV geometric groups (normal, concentric remodeling, eccentric hypertrophy and concentric hypertrophy). Results: No significant difference between the genders was observed regarding the prevalence of the LV geometric groups. Mean values of most evaluated echocardiography and Doppler variables differed between men and women, such as LA, IVS, ...
Complications of hypertension are clinical outcomes that result from persistent elevation of blood pressure. Hypertension is a risk factor for all clinical manifestations of atherosclerosis since it is a risk factor for atherosclerosis itself. It is an independent predisposing factor for heart failure, coronary artery disease, stroke, renal disease, and peripheral arterial disease. It is the most important risk factor for cardiovascular morbidity and mortality, in industrialized countries. Hypertensive heart disease is the result of structural and functional adaptations leading to left ventricular hypertrophy, diastolic dysfunction, CHF, abnormalities of blood flow due to atherosclerotic coronary artery disease and microvascular disease, and cardiac arrhythmias. Individuals with left ventricular hypertrophy are at increased risk for, stroke, CHF, and sudden death. Aggressive control of hypertension can regress or reverse left ventricular hypertrophy and reduce the risk of cardiovascular disease. ...
The concordance rates between left ventricular hypertrophy and right ventricular hypertrophy in patients with hypertrophic cardiomyopathy as diagnosed by CMR with fibrosis imaging. // Journal of Cardiovascular Magnetic Resonance (BioMed Central);2010 Supplement 1, Vol. 12, p1 An abstract of the article "The concordance rates between left ventricular hypertrophy and right ventricular hypertrophy in patients with hypertrophic cardiomyopathy as diagnosed by CMR with fibrosis imaging," by Saundra B. Grant, June A. Yamrozik, Mark Doyle, Ronald B. Williams, Diane A. Vido,... ...
Left ventricular hypertrophy, defined as an increase in the mass of the left ventricle may occur as a physiologic response to exercise (athletic remodeling aka athletic heart), but is most frequently encountered as a pathological manifestation of cardiovascular disease. The early determinants of athletic remodeling in the general population are largely unknown. In order to longitudinally explore the early determinants of athletic remodeling, we will recruit from the community, physically untrained women who have volunteered to run a marathon. We will prospectively assess left ventricular mass and function by echocardiogram during three consecutive stages/visits:. ...
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Discussion. In the animal models of left ventricular hypertrophy triggered by pressure overload, such as aortic stenosis and arterial hypertension, ventricular remodeling consists of an increase in the thickness of the wall, an increase in the diameter of the myocytes, and changes in the myocardial interstitial components, which most of the time include accumulation of myocardial collagen 21-23. Data in the literature 21 have shown that spontaneously hypertensive rats and those undergoing banding of the thoracic aorta have initially normal contractile function and ventricular performance, which evolve to progressive depression of the contractile status, heart failure, and early death. These animal models are useful for long-term evaluations of the morphological, biochemical, and functional characteristics of left ventricular hypertrophy, as well as the assessment of the drug effect on mortality, left ventricular hypertrophy development, and heart failure. When the aortic banding is performed in ...
Using One-Way ANOVA test and linear regression methods, the TAFO defined hydration status, but not the FO/ECW, kept a significant relationship with LAVI (p=0.03). When including age, sex, ethiology, dialysis vintage, comorbidities, dialysis technique, hypertension, biochemical parameters (Hemoglobin, Na, K, Albumin, Creatinin), and all echocardiographic measurements including valvular regurgitation and left ventricle mass index, the only confounding factors identified were lean and fat mass percentages related to total weight, and diastolic function measured by transmitral velocities ratio, but the adjusted relationship kept significant (p=0.036).. Plasma sodium was not different between the 37 patients with (136.6mEq/l; CI 95% 135.8-137.4) and 35 patients without (137.3mEq/l; IC95% 136.1-138.6) atrial dilatation (p=0.314).. Left ventricle hypertrophy was present in 73.7% of patients and concentric remodeling in 7.9%. Concentric hypertrophy was present in 63.2% of patients and eccentric ...
Autori: Covic AC, Buimistriuc LD, Green D, Stefan A, Badarau S, Kalra PA.. Editorial: Ann Noninvasive Electrocardiol Mar;, 18(2):, p.188-98. do, 2013.. Rezumat:. Cuvinte cheie: ventricular hypertrophy ...
In essential hypertension, the regression of left ventricular hypertrophy is an important goal of treatment. In addition to treatment-associated changes in blood pressure (BP), the roles of other determinants of left ventricular hypertrophy regressio
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BACKGROUND: Exercise lowers blood pressure and improves cardiovascular function, but little is known about whether exercise impacts cardiovascular morbidity and mortality independent of left ventricular hypertrophy (LVH) and LV geometry. DESIGN: Observational analysis of prospectively obtained echocardiographic data within the context of a randomized trial of antihypertensive treatment. METHODS: A total of 937 hypertensive patients with ECG LVH were studied by echocardiography in the Losartan Intervention For Endpoint reduction in hypertension study. Baseline exercise status was categorized as sedentary (never exercise), intermediate (30 min twice/week). During 4.8-year follow-up, 105 patients suffered the primary composite endpoint of myocardial infarction (MI), stroke, or cardiovascular death. MI occurred in 39, stroke in 60, and cardiovascular death in 33 patients. RESULTS: Sedentary individuals (n = 212) had, compared with those physically active (n = 511), higher heart rate (P,0.001), ...
Hypertrophic Cardiomyopathy - a condition where the muscle mass in the left ventricle "hypertrophies". The thickened heart muscle can block blood flow out of the heart and can increase the risk of ventricular fibrillation. In over half of the cases, this heart disorder is hereditary and is most common in young adults. This is the most common cause for sudden cardiac death in athletes in the United States ...
More than 50 years have passed since the Framingham Heart Study investigators published their first major report on "risk factors" for coronary heart disease (1). Kannel et al. (1) discovered 3 risk factors, namely elevated blood pressure, elevated cholesterol levels, and electrocardiographic left ventricular hypertrophy. These discoveries stimulated decades of research efforts, which revolutionized our approach to hypertension and hypercholesterolemia. There is little question that much of the 50-year decline in cardiovascular disease death rates can be partially attributed to the seminal contributions of the Framingham epidemiologists.. Within a few months of the Framingham publication, Dr. George Saiger of Columbia University published a commentary on the "10 uses of epidemiology" (2). In the early 1960s, scientists were coming to recognize that epidemiology as a field was expanding beyond infectious disease. Saigers 10 uses included measuring risk, aiding in the search for causes of ...
This afternoon Ive got an appointment with a new massage therapist, so Ive been going over in my mind what I need to say to her: I have about thirteen chronic illnesses [regular readers can skip this part], including severe and unstable obstructive sleep apnea, left ventricle hypertrophy, right branch bundle block, labile hypertension, pulmonary…
Dilatation of the left ventricle results to lateral and downward displacement of the cardiac apex on frontal chest radiographs. Left ventricular hypertrophy usually results to rounded appearance of the cardiac apex. ...
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