NATURAL SCIENCE™ ADULT GUINEA PIG FOOD is specially formulated with high quality ingredients selected to promote the overall wellness of an adult guinea pig. When fed as a maintenance food along with unlimited grass hay and water, Natural Science&tr

TY - JOUR. T1 - Acute Streptococcus pneumoniae Meningogenic Labyrinthitis. T2 - An Experimental Guinea Pig Model and Literature Review. AU - Blank, Andrew L.. AU - Davis, Gustave L.. AU - Vandewater, Thomas R.. AU - Ruben, Robert J.. PY - 1994/12. Y1 - 1994/12. N2 - Objective: To create an experimental model of Streptococcus pneumoniae type 3 meningogenic labyrinthitis (a leading cause of deafness) similar to that in human disease. Design: Cohort analytic study of guinea pigs that were inoculated intrathecally with varying dilutions of S pneumoniae type 3; the progress of the disease was compared with that in saline solution-inoculated control animals. Subjects: Healthy adult Hartley guinea pigs without clinical evidence of middle ear disease that were conveniently sampled. Interventions: Intrathecal inoculation of 104 to 106 colony-forming units of S pneumoniae type 3 into 13 guinea pigs; signs and symptoms of meningitis/labyrinthitis were observed for 15 days and compared with those in two ...

They are very social animals and can live with other guinea pigs. Male guinea pigs should not be housed together. If aggression is noticed, you need to separate your pigs right away. You may notice them engaging in barbering (chewing on each others hair); this is normally not an aggressive behavior. It can be caused by many things, such as boredom, excitement, or dietary deficiencies.. When housing multiple guinea pigs, the cage needs to be large enough for food dishes, toys, and still allow room for them to move around. The cage for a single guinea pig should be at least 24inch w X 18inch h. The cage should have a wire top and sides with a solid base; wire flooring can cause irritation to their feet. Wire sides allows plenty of airflow and ventilation in the cage. Guinea pigs should be housed where there are no drafts, chills, excessive heat, or sudden temperature changes. The base of the cage should be three inches high to keep the bedding in, yet still allows the pig to see whats going on ...

Fig. 3. Development of stable STZ-induced diabetes requires coexisting diet-induced impaired glucose tolerance. (A) Diagrammatic representation of optimized STZ treatment to induce hyperglycemia in guinea pigs fed either normal or HFHC diet. STZ powder is dissolved in citrate buffer at 100 mg/ml, then incubated for 2 h to allow for α/β anomer equilibration. Twenty minutes before STZ treatment, guinea pigs are administered a 0.5 mg/kg dose of the α2 agonist yohimbine, by the intramuscular (IM) route. Guinea pigs are then given a single 200 mg/kg subcutaneous (SC) injection of anomer-equilibrated STZ. Diabetic hyperglycemia is determined by an oral glucose tolerance test (OGTT) at day 7, 14 and 21, based on a 2 h blood glucose ≥200 mg/dl. (B) Blood glucose concentrations were measured daily at random in nonfasted, STZ-treated guinea pigs fed a normal diet (n=5). Hyperglycemia, observable 24 h after STZ treatment, has a trend of steady decline over the course of 14 days. *P,0.05 compared with ...

1- Where can i get or own a guinea pig? Any advices? Although there are lots of helpful information about guinea pigs in our site, there isnt any selling or adoption announcement. Our first advice about it is following adoption announcements from social media platforms. Second is finding a breeding ranch of guinea pigs.. Your last choice must be pet shops. Reason why; not all of them but the majority of pet shops are selling unhealthy miserable baby guinea pigs. On the other hand, if they keep together males and females, the guinea pig youre going to buy could be pregnant. Guinea pigs can get pregnant after 28 days of born. So your guinea pig could give a too soon unhealthy birth.. Sometimes we share adoption announcements which are coming from our followers, via our social media accounts. To check these announcements you can follow us on social media. To find us on social media, you can use social media icons in our website. ...

The Guinea pig maximisation test (GPMT) is an in vivo test to screen for substances that cause human skin sensitisation (i.e. allergens). It was first proposed by B. Magnusson and Albert Kligman in 1969 and described in their 1970 book Allergic Contact Dermatitis in the Guinea Pig The test animals are exposed intradermally to the test material, along with an adjuvant to enhance the immune reaction of the guinea pig. The guinea pigs are then a short while later exposed to a lower concentration of the test material, and their allergic reaction, if any, measured. 15% of guinea pigs must show a reaction for the test to be considered positive. 20 animals would typically be used to ensure against false negative results. The OECD Guidelines for the Testing of Chemicals guideline No. 406 of 1992. The test has been largely superseded by the murine local lymph node assay. D.A. Basketter and E.W. Scholes reviewed them in 1992 The REACH Regulation, Annex VII, paragraph 8.3 states The Murine Local Lymph ...

The incorporation of 32Pi into phospholamban, troponin I, phosphatidylinositols, and inositol trisphosphates was studied in Langendorff-perfused guinea pig hearts stimulated with isoproterenol. Hearts were perfused with Krebs-Henseleit buffer containing [32P]Pk and freeze-clamped at different times during the positive inotropic response. Exposure of the hearts to 0.1 microM isoproterenol for up to 1 minute was associated with significant (up to threefold) increases in phospholamban and troponin I phosphorylation, but there was no significant increase in 32P incorporation into phospholipids. However, longer exposure (2 minutes or more) to isoproterenol was associated with increases in the degree of 32P labeling of phosphatidylinositols and phosphatidic acid. Examination of 32P labeling of inositol trisphosphates in the same hearts revealed that the radioactivity associated with these compounds decreased with time. The decreases were significant at times of exposure of 2 minutes or longer to ...

GGA may induce transcriptional activation of HSP genes, and this novel action may increase gastric mucosal defense at conditions of stress.

Pyrethroid insecticides are known to modify neuronal sodium channels, inducing persistent, steady-state sodium current at depolarized membrane potentials. Cardiac myocytes are also rich in sodium channels but comparatively little is known about the effect of pyrethroids on the heart, or on the cardiac sodium channel isoform. In the present study therefore, we determined the actions of type I and type II pyrethroids against rat and guinea pig ventricular myocytes under current and voltage clamp, and on isolated perfused rat hearts. In myocytes, tefluthrin (type I) and fenpropathrin and alpha-cypermethrin (type II) prolonged action potentials and evoked afterdepolarizations. The time course of sodium current (I(Na)) was also prolonged by these compounds. Pyrethroids delayed I(Na) inactivation, when measured under selective conditions as current sensitive to 30 microM tetrodotoxin, by increasing the proportion of slowly inactivating current at the expense of fast inactivating current. ...

Pyrethroid insecticides are known to modify neuronal sodium channels, inducing persistent, steady-state sodium current at depolarized membrane potentials. Cardiac myocytes are also rich in sodium channels but comparatively little is known about the effect of pyrethroids on the heart, or on the cardiac sodium channel isoform. In the present study therefore, we determined the actions of type I and type II pyrethroids against rat and guinea pig ventricular myocytes under current and voltage clamp, and on isolated perfused rat hearts. In myocytes, tefluthrin (type I) and fenpropathrin and alpha-cypermethrin (type II) prolonged action potentials and evoked afterdepolarizations. The time course of sodium current (I(Na)) was also prolonged by these compounds. Pyrethroids delayed I(Na) inactivation, when measured under selective conditions as current sensitive to 30 microM tetrodotoxin, by increasing the proportion of slowly inactivating current at the expense of fast inactivating current. ...

Although there are a lot of guinea pig illnesses, guinea pigs are more likely to suffer from some issues than others, so its advisable to be on the lookout for bloat, bladder stones, cysts, uterine, tooth, foot or scent gland problems, stained urine and parasites. You can read more about all of these problems via the link above, but as there are so many potential illnesses its a good idea to have a good guinea pig illness encyclopaedia too.. ...

Copyright by Jeannette Gardner (March, 2012). I never really knew how smart guinea pigs are, and that they can actually have you wrapped around their little finger by their cute demands. We adopted two guinea pigs, mother and daughter of 1 and 3 years old in October of 2011. After buying a house, we wanted to get a pet, and decided against getting a dog for now. Instead, we are proud parents of two loveable guinea pigs, Harmony and Melody. Hey, you dont have to walk them at all hours of the day or evening! Our two adorable piggies have out smarted us in a lot of funny but very cute ways. They know our schedules for eating, and by this what amazes me is that they know of the exact timing of different hours for our meals, and for them to get their pellets and their treats. Im normally the first one up, get the coffee on and check up on our guinea pigs. Its really funny to watch them at that time as they are both standing up on their little front legs on their empty bowl looking at me, and ...

This page contains the abstract: Effect of Coenzyme Q10, a Quinone Derivative, on Guinea Pig Lung and Tracheal Tissue http://www.chiro.org/nutrition/ABSTRACTS/Coenzyme_Q10_Allergy.shtml

Loud bangs and whistles can cause guinea pigs a great deal of stress. Help your pet to cope with fireworks from Bonfire Night all the way through to New Years Eve with these handy tips…. Give your guinea pig lots of extra bedding so they can burrow down in it and get cosy. You could put a cardboard box full of hay in their hutch to give them an extra place to shelter in safety. Remember to cut holes in boxes for easy access and exit.. Bring your guinea pigs hutch or cage indoors. A quiet room is best, but an unused garage or shed is a good alternative if you cant bring them into your house.. If you cant bring your pets inside, turn their enclosure around so it faces a wall or fence instead of the open garden. This will help to stifle the sound and prevent them from seeing the flashes of light. Cover their hutch with thick blankets or a duvet to block out the sound of the bangs and the sight of the fireworks, but make sure your pet still has enough ventilation.. If your guinea pigs usually ...

When the autumn time comes, the most beautiful things in nature are the leaves! When leaves fall from the trees, everything around is painted with the gorgeous natural colors; yellow, red, orange, brown, crimson. Have you ever wondered if leaves are edible for some animals? Or maybe which tree leaves? In this article we will discuss whether guinea pigs can eat leaves, so please keep on reading.. Can guinea pigs eat leaves? Yes, guinea pigs can eat leaves but only certain types. This means they can eat leaves only from certain trees and branches. If you cannot identify the tree, it is best to avoid feeding the guinea pig an unidentified leaf. There are safe trees which can give the cavy some leaves to munch on. The most common leaves they can chew on are from the fruit trees. They can have apple, pear, willow, citrus tree, banana leaves, sunflower leaves pumpkin, mango, raspberry, grape, outer leaves of corn, cauliflower leaves, and mulberry too. Also, they can even have certain branches, such as ...

The Eglu Go Hutch is perfect for keeping rabbits and guinea pigs in the garden safely. The Eglu Go Guinea Pig Hutch and run is suitable for two to three guinea pigs, and the Rabbit hutch and run is ideal for two pet bunnies. The plastic rabbit and guinea pig house is easy to clean and insulated, making it perfect to use all year round and both come with fox-resistant run. See below to read about the Eglu Go Hutch.

TY - JOUR. T1 - Signal requirements for lymphocyte activation. T2 - Role of a T-cell growth factor produced by guinea pig peritoneal exudate lymphocytes. AU - Weinblatt, Anita Corman. AU - Oppenheim, Joost J.. AU - Rosenstreich, David L.. PY - 1982/4. Y1 - 1982/4. N2 - Peritoneal exudate lymphocytes (PEL) from immunized guinea pigs, when pulsed with antigen, rapidly release a T-cell stimulatory factor (TSF). TSF nonspecifically enhances the proliferation of purified guinea pig T cells in the presence of another signal such as PMA, PHA, or Con A. On a per cell basis, antigen-pulsed PEL produce about 14 times more activity than similarly stimulated lymph node lymphocytes. Several lines of evidence support the view that TSF is the guinea pig equivalent of TCGF (IL-2). TSF containing supernatants have IL-2 activity when assayed on the IL-2-dependent CT6 cell line. When TSF containing supernatants were absorbed with CT6 cells, there was a significant decrease of both TSF activity as assessed on ...

TY - JOUR. T1 - Dynamic mammalian cardiogenesis investigated by high-resolution ultrasound in guinea pigs. AU - Loeber, C.. AU - Goldberg, S. J.. AU - Hendrix, M. J.C.. AU - Sahn, D. J.. PY - 1983. Y1 - 1983. N2 - Ultrasonic cardiac imaging of human fetuses has been feasible only after 12 to 14 weeks gestation when the heart is completely formed. The authors purpose was to develop a method of examining dynamic mammalian cardiogenesis with a high-resolution 9 MHz ultrasound scanner. Fetal guinea pig hearts were imaged in utero over the course of 10 days. All images were obtained after blastocyst implantation estimated to occur 8 days after fertilization with cardiogenesis occurring over the next 14 days. After laparotomies were performed on the gravid guinea pigs, sterile transducers were placed on their uterine horns and ultrasonic images were obtained. Further optical magnification of videotaped images was required to visualize cardiac details. Ten gravid guinea pigs were examined and 3 of 10 ...

TY - JOUR. T1 - Acoustic trauma in the guinea pig cochlea. T2 - Early changes in ultrastructure and neural threshold. AU - Robertson, Donald. AU - Johnstone, Brian M.. PY - 1980/1/1. Y1 - 1980/1/1. N2 - Scanning microscopy was used to examine guinea pig cochleas for structural damage immediately after exposure to a pure tone ranging from 96 to 129 dB SPL. Functional changes to the cochlear neural sensitivity were assessed using the N1 audiogram. Principal findings were: (1) The order of damge to receptor cells with increasing sound intensity was OHC1, then IHC, then OHC2 and OHC3. (2) The spatial distribution of damage to OHC1 and IHC differed with IHC tending to show damage mainly in the vicinity of the exposure frequency location and OHC1 damage spreading basalward of this point. (3) N1 threshold losses spread progressively to lower frequencies as exposure intensity increased. This was accompanied by an apical spread of damage to the receptor cells.. AB - Scanning microscopy was used to ...

Guinea pig The guinea pig (Cavia porcellus), also called the cavy, is a species of rodent belonging to the family Caviidae and the genus Cavia. Despite their common name, these animals are not in the pig family, nor are they from Guinea. They originated in the Andes, and earlier studies based on biochemistry and hybridization…

Aftercontractions, delayed afterdepolarizations, and automaticity occurred in guinea pig papillary muscles that were reoxygenated after hypoxic conditioning. The emergence of dysfunction was dependent on the severity of hypoxic conditioning and on stimulation during reoxygenation. After 60 minutes of substrate-free hypoxia, reoxygenation induced automaticity in a high proportion of stimulated muscles; the automaticity appeared within 1 minute and lasted for 10-20 minutes. After similar conditioning, muscles reoxygenated for 7-15 minutes were stimulated at various cycle lengths. The incidence of automaticity and the amplitudes of delayed events had W-shaped dependencies on cycle length (200-1,000 msec), whereas coupling intervals had M-shaped dependencies. In ventricular myocytes that displayed automaticity after reoxygenation, extrasystolic upstrokes arose smoothly from delayed afterdepolarizations that reached threshold. In tissue, extrasystolic upstrokes usually rose sharply from delayed ...

The in vitro activities and interactions of macrophages and lymphocytes from tuberculin-sensitive and normal guinea pigs, in the presence or absence of antigen (PPD), were examined with the aid of phase-contrast time-lapse cinematography. Macrophages from peritoneal exudate had active amoeboid motion and numerous rapidly extending pseudopodia. Macrophages from normal or sensitized animals, in the presence of antigen and sensitized lymphocytes, and to a lesser extent sensitized thymocytes, formed considerably less active and less numerous pseudopodia, became spherical and were more sluggish in their movements. The motion of lymphocytes and thymocytes, normal or sensitized, was not affected by specific antigen. Non-sensitized macrophages aggregated and tended to become associated with lymphocytes in the presence of antigen and sensitized lymphocytes. These in vitro observations provided direct evidence of immunologically induced cellular interactions in delayed hypersensitivity systems.. ...

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TY - JOUR. T1 - Spatial heterogeneity of transmembrane potential responses of single guinea-pig cardiac cells during electric field stimulation. AU - Sharma, Vinod. AU - Tung, Leslie. PY - 2002/7/15. Y1 - 2002/7/15. N2 - Changes in transmembrane voltage (Vm) of cardiac cells during electric field stimulation have a complex spatial- and time-dependent behaviour that differs significantly from electrical stimulation of space-clamped membranes by current pulses. A multisite optical mapping system was used to obtain 17 or 25 μm resolution maps of Vm along the long axis of guinea-pig ventricular cells (n = 57) stained with voltage-sensitive dye (di-8-ANEPPS) and stimulated longitudinally with uniform electric field (2, 5 or 10 ms, 3-62 V cm-1) pulses (n = 201). The initial polarizations of Vm responses (Vmr) varied linearly along the cell length and reversed symmetrically upon field reversal. The remainder of the Vm responses had parallel time courses among the recording sites, revealing a common ...

Unlike many other pets, such as dogs, cats, or rabbits, guinea pigs typically need minimal grooming and are fairly simple to care for. Most guinea pig owners find that with a little training, they can learn to groom their pets at home.

To determine whether guinea pigs are infected with influenza virus in nature, we conducted a serologic study in domestic guinea pigs in Ecuador. Detection of antibodies against influenza A and B raises the question about the role of guinea pigs in the ecology and epidemiology of influenza virus in the region.

Incubation in vitro of the intestine of the hamster and guinea pig with 5 mM sodium cholate and with 2 mM sodium deoxycholate and sodium chenodeoxycholate resulted in significant morphological changes compared with control incubations. Generally, no major differences were observed between proximal and distal small intestine or between the species used. Only when guinea pig intestine was incubated with 5 mM cholate was less damage found proximally than distally.. Perfusion in vivo of the intestine of the hamster and guinea pig with Krebs-Ringer phosphate results in separation of the epithelium from the lamina propria without excessive shedding of epithelial cells from villous tips. This change was also seen in specimens taken before perfusion and probably represents unavoidable trauma during handling of the intestine.. In contrast to studies in vitro, regional differences are readily demonstrable with perfusion of bile salts in vivo. Dihydroxy bile salts produce more marked alterations of both ...

Results of Western blot analysis carried out with an interstitial cell extract from male guinea pig and ovarian extract from immature female rats administered equine chorionic gonadotropin (eCG) provide supportive evidence to our earlier suggestion that an 8-kDa peptide is involved in acquisition of steroidogenic capacity by the rat Leydig cells. It was found that though the signal was observed in other tissues such as liver, kidney and lung which do not produce gonadal hormones, the peptide was modulated only by lutenizing hormone (LH) in the rat Leydig cells.. ...

Care+ is an extremely palatable and well-balanced super-premium feed that has been developed in collaboration with veterinary surgeons, dieticians and leading guinea pig experts. Care+ is enriched with extra vitamin C and also contains proteins of high biological value for optimum growth. This food has low fat content and contains Omega 6 and Omega 3 fatty acids, Echinacea and Spirulina. The Vit E Cell Protection System protects your guinea pig s cells against damaging external influences. Chelated minerals improve absorption and supply to the body, resulting in a healthy mineral balance in the body. FOS and MOS are included as prebiotics. Yucca schidigera extracts help to minimize the odor of faeces and urine. The variety of different ingredients in Care+ ensure that your guinea pig is cheerful, vivacious and guarantees a long and healthy life. With Care+ you can be sure that you have the best food for your guinea pig ...

Guinea pigs can sometimes expel air from their nose and sneeze as we do. This will sound very high-pitched, but is unmistakably a sneeze. Its not usually something to be concerned about, as its usually the result of dust - many guinea pigs will sneeze when they receive hay (but try to get the least dusty hay possible to try to prevent respiratory tract infections). If your guinea pig is sneezing a lot, then it may be cause for concern, as it could be indicative of an infection or an allergy.. ...

This is different to all my other books and definitely makes me want to read on! It has brilliant characters - Coco is funny because she is so posh and says she lives with the Queen!. Sophia, age 7. I liked this book when at the end Eduardo and Coco fall in love and scooter away. I love guinea pigs and I have 4 of my own so really enjoyed this story. This book had lots of funny bits in it. Banoffee had lots of babies. I liked it when Terry helped Coco on the internet find out where Meat Cleaver is. I would love it if my guinea pigs did all this when I was at school. My favourite guinea pig character was Coco as she was a princess. My favourite person was Henrietta because she was Cocos owner. Fuzzy likes the internet and Coco does not I wonder why? This book was great and would be fab for boys or girls 5 and older. Guinea pigs online was so good I did not want to put it down until I had finished it.. Stephanie, age 6. ...

The kidney of guinea pigs infected with the H37Rv and BCG strains of M. tuberculosis showed a diminution in succinic dehydrogenase activity when measured by the tetrazolium technique. This effect was also seen in the liver and spleen of animals infected with the BCG strain. Sensitized animals showed similar results when given tuberculin in sublethal doses. The succinic oxidase was also low in the kidneys of animals infected with the H37Rv strain.. The depressed enzyme activity of the tissues of infected animals could be restored to normal by addition of normal tissue extract or dialysate. This suggests that the alteration in tissue metabolism observed in tuberculosis may depend upon the loss of some as yet unidentified factor important for succinic dehydrogenase activity.. ...

May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain (By similarity).

BioAssay record AID 149839 submitted by ChEMBL: In vitro inhibition for opioid binding site in guinea pig brain membrane using [3H]U-69593 as radioligand.

BioAssay record AID 204454 submitted by ChEMBL: In vitro binding affinity towards sigma receptor by the displacement of [3H]PPP from guinea pig brain.

Copyright: © 2017 Umba et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cited.. Abstract. To increase availability of animal proteins in Democratic Republic of the Congo (DRC), Cavia porcellus was recently enrolled in a breeding program that includes base populations from DRC and Belgium. To preserve whole or part of the sources genetic diversity over breeding cycles, cognizance of genetic diversity in natural populations is required. We tested the cross-amplification of eleven pairs of microsatellite primers that were isolated from Cavia aperea and C. magnea. Amplification tests by polymerase chain reaction were performed on total DNA of 30 C. porcellus using 11 microsatellite loci. All the microsatellites amplified at the expected size and were polymorphic for C. porcellus. Using these microsatellite loci, we ...

Goat Anti-Guinea Pig IgG (H&L) Antibody (Polyclonal IgG) - Rhodamine Cat#20330101 Details Host:Goat Isotype:IgG Class:Polyclonal Immunogen:Guinea Pig IgG (H&L) Conjugate:Rhodamine Form Information Form:Liquid Concentration:2 mg/mL Purification:Protein A Chromatrography Storage Buffer:PBS with 0.1% BSA Preservative:Upon Request (0.02% Sodium Azide) Storage:Shipped at 4°C. Upon delivery aliquot and store at -20°C in the dark. Avoid freeze / thaw cycles. Usage Recommendations Western Blot (WB):1:3000-1:5000 ELISA:1:150-1:400 Immunoprecipitation (IP):1:350 - 1:500

coloring pages of guinea pigs guinea pig coloring pages coloring page of pig pig coloring pages pig coloring pages pig color page pig coloring pages printable guinea pig coloring pages colouring pages.. ...

Parsley is a spiced vegetable belonging to the herb family is grown all over the world, though it is natively originated from the Central Mediterranean region. The Parsley can be prepared as a snack or used as an additional ingredient in soups and stews.. Guinea can eat Parsley! Yes, the answer is yes. Parsley is rich in vitamin C, thus the intake of this in large quantities will only increase the vitamin level in the Guinea pigs body. Note that small creatures cannot produce vitamin C on their own. Parsley is rich in other minerals too. Additionally, this is low in calories. Thereby making parsley the best food for consumption by guinea pigs.. This Parsley can be used for those who wish to bring down their weight at the same time remaining healthy. Thus, Parsley is extremely safe for your guinea pigs.. Also, make a note that any excessive intake of food would lead to uncomfortableness. Similarly, over intake of Parsley would also cause side effects. Hence, eating parsley in moderate quantities ...

If you do decide to go with disposable guinea ped bedding, there is absolutely no doubt you should choose paper-based bedding and not wood-based bedding.. Some people use shredded newspaper as bedding, but it doesnt absorb liquid or odors much at all. If you dont clean the cage frequently, you could get quite a nasty mess.. Paper bedding is a go-to choice for many guinea pig owners. It is because it is soft, absorbent, and good at odor control. The trouble is, even though different paper bedding brands are essentially made out of the same material, they come in varying qualities and types. This makes it hard for pet parents to figure out which product is most ideal.. Aspen bedding. Unlike pine and cedar shavings which should not be used (more about that at the bottom of this post), aspen bedding is a completely safe option, often recommended by the vets.. Is hemp bedding safe for guinea pigs?. Hemp-based beddings are safe for guinea pigs. They are very absorbent, odorless, dust-free and soft. ...

Liu, H.P.,Tay, S.S.,Leong, S.K. (1997). An ultrastructural study of the innervation of the guinea pig pancreas.. Journal für Hirnforschung 38 (1) : 107-117. ScholarBank@NUS Repository ...

Bile salts stimulate glycoprotein release by guinea pig gallbladder in vitro.s profile, publications, research topics, and co-authors

Well not one like this little guy in the photo, he is ours, his name is Pippin and he doesnt embroider. And its not about a pattern of a guinea pig either, which is what a lot of people thought when I posted this in the Follow the White Bunny Flickr group. Im looking for someone who wants to test-drive a new Alice in Wonderland pattern later this month. Please comment in the Flickr group if you are interested. You may wonder why I dont try it out myself. First of all Ive got many things going on and if I felt like I have to embroider, it would almost feel like work and the whole embroidery-experience would not be so relaxing anymore. The other thing is that often Ive been drawing and re-drawing a pattern many times so I appreciate someone else taking a look at it and trying it out. Oh and please dont be sad if I dont pick you now, Ive got heaps of ideas for upcoming patterns so new guinea pigs are needed in the future ...

Guinea pigs are prone to heatstroke in high temperatures and, sadly, the condition can prove fatal. Find out how to keep your guinea pigs cool.

TY - JOUR. T1 - S-isopetasin, a sesquiterpene of Petasites formosanus, allosterically antagonized carbachol in isolated guinea pig atria. AU - Ko, Wun Chang. AU - Wang, Sheng Hao. AU - Chen, Mei Chun. AU - Lin, Yun Lian. AU - Chen, Chieh Fu. PY - 2002. Y1 - 2002. N2 - We investigated the antimuscarinic effect of S-isopetasin in isolated guinea pig atria to clarify whether it preferentially acts on muscarinic M2 or M3 receptors. The tension changes of isolated atria were isometrically recorded on a polygraph. S-Isopetasin at 50 and 100 μM significantly inhibited baselines of contractile tension and heart rate, but atropine at 1 μM enhanced both. S-Isopetasin (10-100 μM) did not significantly alter the concentration-negative inotropic response curves of carbachol (CCh) in left atria. S-Isopetasin (10-100 μM) allosterically antagonized negative inotropic and chronotropic responses induced by CCh in spontaneously beating right atria, based on the slopes of Schild plots significantly differing ...

Technique Summary Resources and references Saphenous vein sampling in other animals All blood sampling techniques in the guinea pig Please read the general principles of blood sampling page before attempting any blood sampling procedure. Technique Sampling from the lateral saphenous vein is a relatively quick method of obtaining blood samples from all strains of guinea pig. It does not require the animal to be warmed. Slides and videos of restraint, shaving and sampling for this technique with mice are available on the websites of the Norwegian Reference Centre for Laboratory Animal Science. Blood is collected from the lateral saphenous vein, which runs dorsally and then laterally over the tarsal joint. Conscious guinea pigs should be restrained either manually or using a restraint tube. This can cause stress and therefore the duration of restraint should be minimised. Where a restraint tube is used, it should be appropriate for the size of the guinea pig. All forms of restraining equipment should be

TY - JOUR. T1 - Interaction of antibody with Forssman antigen in guinea pigs. T2 - A mechanism of adaptation to antibody- and complement-mediated injury. AU - Yuzawa, Y.. AU - Brett, J.. AU - Fukatsu, A.. AU - Matsuo, S.. AU - Caldwell, P. R.B.. AU - Niesen, N.. AU - Milgrom, F.. AU - Godman, G.. AU - Stern, D.. AU - Andres, G.. PY - 1995. Y1 - 1995. N2 - Forssman antigen is a glycosphingolipid with antigenic specificity determined by extra-membrane haptenic sugars similar to blood group antigens and antigens that are the main barrier to xenogeneic organ transplantation. Herein, we describe the localization of Forssman antigen in guinea pig lungs and kidneys and the consequences of its interaction with antibodies in vitro and in vivo (Forssman reaction). Exposure of cultured guinea pig aortic endothelial cells to Forssman antibodies induced rapid redistribution of antigen-antibody complexes at the cell surface, followed by shedding that occurred by blebbing of plasma membrane as vesicles or ...

Alpha 2 adrenergic receptors are located prejunctionally in the Auerbachs plexus of the guinea pig small intestine: direct demonstration by radioligand binding.

In addition to their proliferative and differentiating effects, several growth factors are capable of inducing a sustained airway smooth muscle (ASM) contraction. These contractile effects were previously found to be dependent on Rho-kinase and have also been associated with the production of eicosanoids. However, the precise mechanisms underlying growth factor-induced contraction are still unknown. In this study we investigated the role of contractile prostaglandins and Rho-kinase in growth factor-induced ASM contraction. Growth factor-induced contractions of guinea pig open-ring tracheal preparations were studied by isometric tension measurements. The contribution of Rho-kinase, mitogen-activated protein kinase (MAPK) and cyclooxygenase (COX) to these reponses was established, using the inhibitors Y-27632 (1 μM), U-0126 (3 μM) and indomethacin (3 μM), respectively. The Rho-kinase dependency of contractions induced by exogenously applied prostaglandin F2α (PGF2α) and prostaglandin E2 (PGE2) was

OBJECTIVE: To study the influence of glycyrrhetinic acid (GA) on bronchial asthma (BA) smooth muscle proliferation and apoptosis as well as inflammatory factor expression and its molecular mechanism. METHODS: Male SD guinea pigs were selected and made into asthma models, bronchial asthma smooth muscle cells were cultured and divided into BA group, GA group and GA + LM group that were treated with serum-free RPMI1640 culture medium, serum-free RPMI1640 culture medium containing 50 ng/mL glycyrrhetinic acid, serum-free RPMI1640 culture medium containing 50 ng/mL glycyrrhetinic acid and 100 ng/mL LM22B-10 respectively; normal guinea pigs were collected and bronchial smooth muscle cells were cultured as control group ...

Introduction: In previous studies, the relaxant and antihistaminic effects of thymoquinone, the main constituents of Nigella sativa, have been demonstrated on guinea pig tracheal chains. In the present study, the prophylactic effect of (IP) single dose of thymoquinone on tracheal responsiveness and lung inflammation of guinea pig model of asthma was examined. Methods: Thirty guinea pigs were randomly divided to 3 groups; control (C), sensitized (S) and pretreated group with (TQ); 3 mg/kg, IP (S+TQ). Tracheal responsiveness to methacholine and ovalbumin (OA), total and differential cell count in bronchoalveolar lavage, lung pathological changes and blood Interleukin 4(IL-4) and Interferon gamma (IFNγ) level in three groups were measured. Results: Increased tracheal responsiveness to methacholine and OA, lung lavage fluid white blood cell (WBC) and eosinophil count, IL-4 and IFN-γ levels and pathological changes were seen in sensitized group in comparison to control group (p<0.001 to p

TY - JOUR. T1 - Spatial and temporal changes of subchondral bone proceed to microscopic articular cartilage degeneration in guinea pigs with spontaneous osteoarthritis. AU - Wang, T.. AU - Wen, Chunyi. AU - Yan, C. H.. AU - Lu, W. W.. AU - Chiu, K. Y.. PY - 2013/4/1. Y1 - 2013/4/1. N2 - Objective: This study aimed to investigate the spatial and temporal subchondral bone change of Dunkin-Hartley (DH) strain guinea pigs spontaneous osteoarthritis (OA) model at early stage with three-dimensional Microfocal Computed Tomography (Micro-CT) analysis, histology and immunohistochemistry. Materials and methods: Knee joints of DH and Bristol Strain 2 (BS2) guinea pigs were analyzed at 1, 2 and 3 months of age for early staged subchondral bone ultrastructure change of OA by Micro-CT and histology. And cartilage degeneration was monitored by histological examination. In addition, expression of Osterix was quantified by immunohistochemistry. Results: Microscopic cartilage degeneration was not found at first 3 ...

After Stokes, Bauer, and Hudson (1) found the monkey, Macacus rhesus, to be susceptible to the virus of yellow fever, several workers studied the reaction of guinea pigs to this virus. Sellards (2) was able to demonstrate the presence of the virus after three passages in guinea pigs by the transference of blood and spleen, but his results were rather irregular and could not be repeated at will. Sawyer and Frobisher (3), after giving massive intraperitoneal injections of the virus to guinea pigs, could demonstrate the virus in the blood of the animals at various intervals ranging from fifteen hours to five days after inoculation. Blood withdrawn eight or fifteen days after inoculation proved to be free from virus. These authors also showed, by protection tests in monkeys, that the guinea pig responds to an injection of virus by the development of antibodies.

Guinea pigs can eat parsnips, but only in moderation. The parsnip is a veggie that has many benefits for the guinea pigs health. It is packed with many nutrients, vitamins, minerals, fibers, and antioxidants beneficial for them. There arent many problems related to parsnips which makes them a good food for guinea pigs.

The insulin-like growth factors possess growth-promoting activity. Major fetal growth hormone in mammals. Plays a key role in regulating fetoplacental development. IGF-II is influenced by placental lactogen. Also involved in tissue differentiation. Positively regulates myogenic transcription factor MYOD1 function by facilitating the recruitment of transcriptional coactivators, thereby controlling muscle terminal differentiation. In adults, involved in glucose metabolism in adipose tissue, skeletal muscle and liver.

Pichinde virus (PIC) is a reticuloendothelial arenavirus of the New World tropics. A guinea pig passage-adapted strain of this virus (adPIC) is uniformly lethal for inbred guinea pigs, while the related, prototype strain (PIC3739) has attenuated virulence. The abilities of adPIC and PIC3739 to induce tumor necrosis factor (TNF) in vivo and in cultured macrophages were compared. Infection with adPIC, but not PIC3739, was associated with detectable serum TNF that peaked in week 2 of infection. Tumor necrosis factor was found in the spleens of adPIC- and PIC3739-infected animals in week 1 of infection ; TNFα mRNA levels in spleens and livers of adPIC infected animals increased and remained high throughout infection, whereas PIC3739-infected organs showed down regulation of TNFα mRNA late in infection. Peritoneal macrophages explanted from adPIC-infected animals showed enhanced lipopolysaccharide-inducible TNF production. Altered regulation of TNF production may play a role in the pathogenesis of guinea

In the adult brain, monocarboxylates, including lactate, pyruvate, and β-hydroxybutyrate, can be used to produce high-energy phosphates (14,15,18-20) and protect against neuronal damage after hypoxic or ischemic insult (21,22). In the immature brain, monocarboxylates can be used to fuel synaptic transmission during periods of glucose deprivation (23). Therefore, we investigated whether monocarboxylates can be used to sustain synaptic activity in response to repeated hypoglycemia (Fig. 4B), using monocarboxylate transporter (MCT) inhibitors 4-CIN, IBMX, and phloretin (21). 4-CIN prevents monocarboxylate utilization by inhibiting the mitochondrial pyruvate carrier as well as by inhibiting the plasma membrane MCT. First, we tested the effect of 200 μmol/l 4-CIN on 10 mmol/l glucose-supported PS (Fig. 4A). Whereas 0.1% DMSO used for dissolving of 4-CIN did not affect PS amplitude (Fig. 4A, column 1), application of 200 μmol/l 4-CIN suppressed PS amplitude by 43.0 ± 6.8% (column 2) (P , 0.01). In ...

A radioactive analogue of levorphanol, [3H]N-β-(p-azidophenyl)ethylnorlevorphanol (compound 6), has been synthesized as a photochemical affinity label for the opiate receptor site(s). It has potent opiate-like pharmacological activity in whole mice and isolated intact guinea pig ileum Upon photolysis of the analogue in the presence of bovine serum albumin as a test protein, radioactivity is incorporated into the protein. Photolysis of the analogue in the presence of total particulate matter from whole mouse brain results in incorporation of radioactivity into a pellet insoluble in water and organic solvent. This incorporation is significantly but incompletely blocked by both levorphanol and dextrorphan. Incorporation into guinea pig ileum longitudinal muscle strips is also observed but is not significantly blocked by levorphanol or dextrorphan. The implications of the results are discussed.. ...

Lubeluzole is widely reported as a multitarget drug acting at least on voltage-gated calcium and sodium channels. There are, however, only a very few studies reporting direct demonstration of sodium channel blockade by lubeluzole in neuronal and cardiac cells (Osikowska-Evers et al., 1995; Le Grand et al., 2003). The more complete study by Le Grand et al., (2003) described the block of sodium channels in single guinea pig ventricular myocytes. It was shown that lubeluzole produces a concentration-dependent tonic and use-dependent block of cardiac sodium channels in a manner similar to that of class I antiarrhythmic drugs, suggesting a greater affinity for inactivated than for resting channels. In the present study, we observed a similar local anesthetic-like effect of lubeluzole on human skeletal muscle sodium channels, and definitely demonstrated that the drug is a very potent blocker of inactivated sodium channels compared with resting channels. The IC50 values calculated for skeletal muscle ...

PubMed journal article The cannabinoid receptor agonist WIN 55,212-2 inhibits antigen-induced plasma extravasation in guinea pig airway were found in PRIME PubMed. Download Prime PubMed App to iPhone, iPad, or Android

TY - JOUR. T1 - Nuclear Fos immunoreactivity in guinea pig myenteric neurons following activation of motor activity. AU - Ritter, Robert C.. AU - Costa, Marcello. AU - Brookes, Simon H.. PY - 1997/10/13. Y1 - 1997/10/13. N2 - To identify enteric neurons activated during intestinal motor activity, we examined myenteric plexus of guinea pig small intestinal segments for expression of the immediate early gene product, Fos. Fos immunoreactivity was detected immunohistochemically following in vitro manipulations, which included distension, electrical stimulation, exposure to forskolin, and peristalsis. All of these manipulations induced neuronal Fos expression, which was prevented by tetrodotoxin, indicating that expression depended on nerve activity. Distension-induced Fos expression was blocked by ω-conotoxin and significantly reduced by hexamethonium, indicating that neurons expressing Fos immunoreactivity were activated synaptically. Blocking smooth muscle contraction with nicardipine reduced ...

ODONNELL S.R. and SAAR N. (1978) THE UPTAKE KINETICS AND METABOLISM OF EXTRANEURONAL NORADRENALINE IN GUINEA‐PIG TRACHEA AS STUDIED WITH QUANTITATIVE FLUORESCENCE MICROPHOTOMETRY. British Journal of Pharmacology, 62 2: 235-239. doi:10.1111/j.1476-5381.1978.tb08451.x ...

Endogenous norepinephrine content and retention of 3H-norepinephrine were investigated in the vas deferens, seminal vesicle, urinary bladder and left atrium of the guinea pig under several experimental conditions. Castration of adult guinea pigs resulted in a 50% reduction in wet weight of vas deferens and seminal vesicle. Reduction in weight of these tissues was accompanied by a proportional decrease in norepinephrine content and 3H-norepinephrine retention. Administration of testosterone (10 mg/kg s.c.) five times a week for 30 days to castrate adult animals increased the weight of vas deferens and seminal vesicle by 2-to 3-fold. Norepinephrine content and retention also revealed about 2-to 3-fold increase. In spite of simultaneous loss or gain in the wet weights of seminal vesicies and vasa deferentia, their endogenous amine concentration, expressed as micrograms per gram of tissue, remained remarkably constant under a wide variety of experimental conditions. Seventy-five days after ...

Ro 25-1553, a cyclic peptide analog of vasoactive intestinal peptide (VIP), was designed to overcome many of the deficiencies inherent in this natural neuropeptide. On isolated guinea pig tracheal smooth muscle, Ro 25-1553 produces concentration-dependent relaxation of contractile responses to a number of different spasmogens. Depending on the contractile stimulus, Ro 25-1553 is 24 to 89 times more potent than VIP as a relaxant of guinea pig trachea. The high potency of Ro 25-1553 extends to studies on isolated, histamine-contracted, human bronchial smooth muscle, where Ro 25-1553 exhibits a 390-fold enhancement over native VIP and is more potent than other bronchodilating drugs, such as the beta 2-adrenoceptor agonists isoproterenol and salbutamol. Ro 25-1553 was shown to displace the radioligand 125I-VIP from rat forebrain membranes with an IC50 value of 4.98 nM, thereby demonstrating that it acts at a VIP receptor. In addition, when tested in a battery of 40 other binding assays (e.g., ...

Large 19th Century English Boy Portrait & Guinea Pigs Stable Scene ROBERT JAMES. Boy With His Guinea Pigs, dates 1841. Fine large 19th Century Portrait of a young boy with his Guinea Pigs in a stable, oil on canvas by Robert James. Charming large period portrait of the young boy with his beloved pets. Superb detail in both the sitter and his companions. The boy is likely a street urchin or villager the artist took an interest in capturing. Measurements: 47 x 39 framed. Our gallery carefully selects its paintings based on their quality and importance. Surrey Fine Arts only sell original antique oil paintings. As well as our own expertise at Surrey Fine Arts many of our works of art are assessed and authenticated by leading UK and International specialists in their field.. We have exclusive contacts to some of the UKs best restorers. Surrey Fine Arts are specialist. British, Old Masters and Impressionist paintings. The gallery, based in heart of Surrey, carries a large eclectic inventory of ...

Calcium is an essential mineral for several important functions in the body of an animal. Calcium is needed for the development of the fetal skeleton as well as for the secretion of milk in lactating females, making pregnant and nursing guinea pigs more prone to calcium deficiency if their increased nutritional needs are not being met. This related type of calcium deficiency usually develops in the one to two weeks before, or shortly after, giving birth. Also at higher risk of calcium deficiency are obese or stressed guinea pigs, or guinea pigs that have already been pregnant several times.

 Introduction and Description Introduction This is an outside hutch where the guinea pig can spend the warmer months. In the summer an outside hutch is great, guinea pigs love to eat fresh grass. Come winter, this particular guinea pig is moved to a cage inside the house. This hutch…

 Introduction and Description Introduction This is an outside hutch where the guinea pig can spend the warmer months. In the summer an outside hutch is great, guinea pigs love to eat fresh grass. Come winter, this particular guinea pig is moved to a cage inside the house. This hutch…

Stink and the Great Guinea Pig Express by Megan McDonald | Buy Books at Lovereading4kids.co.uk FUR-eaky! Stink and his friends are off on a hairy new mission: finding homes for 101 rescued guinea pigs aboard the Squeals on Wheels Express. The fourth book in the hilarious series about Judy Moodys little bother .Forget dalmatians, Stink has 101 guinea pigs to find homes for! Fans of...Find out more

Youve heard of dogs being mangy, but that term can also apply to guinea pigs. A guinea pig diagnosed with scabies is suffering from mange, caused by fur mites. The scabies mite affecting guinea pigs cant thrive on people, but it can live on you long enough to try a bite, causing an temporary itchy ...

Guinea pigs are generally hardy, healthy animals but are susceptible to certain diseases. They cannot make their own vitamin C and require supplementation or they may develop scurvy. Guinea pigs get various tumors, particularly skin and mammary tumors. Guinea pigs also get abscesses (accumulations of pus and bacteria) in lymph nodes, skin, muscles, teeth, bones, and internal organs. They are very prone to development of urinary calculi that form in the bladder, kidneys, or ureters which may become lodged, causing a life-threatening obstruction. In addition, guinea pigs often are affected by ringworm and can get fleas and lice. Barbering is a problem, usually associated with boredom, in which the guinea pig chews or barbers its own hair or the hair of its cage-mate. Pododermatitis, or bumblefoot, in which sores develop on the bottom of the feet from pressure, is common in overweight animals housed on wire-bottomed or dirty cages that abrade the feet.. Login Required ...

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Lipidated peptides have been shown to induce strong antimycobacterial T cell responses in TB-infected humans (22, 23) and cattle (31). These observations prompted us to investigate whether strong, lipopeptide-specific T cell responses are observed only post infection with M. tuberculosis or whether they are also induced by BCG vaccination. The guinea pig is a well-accepted small animal model for TB because it is naturally susceptible to virulent mycobacteria and, upon infection, reproduces similar pathological changes to those seen in TB patients (32). Using outbred Dunkin-Hartley guinea pigs, we could demonstrate that BCG-vaccinated animals mount strong and robust Th cell responses to hydrophobic peptide Ags present in mycobacterial CMEs. In accordance with observations in humans, these BCG-induced lymphocytes strongly upregulate proinflammatory cytokines upon Ag encounter (Supplemental Fig. 1). The observed reactivity represents a true Ag-specific, adaptive T cell response, because no ...

TY - JOUR. T1 - Isoform-specific regulation of the sodium pump by α- and β-adrenergic agonists in the guinea-pig ventricle. AU - Gao, J.. AU - Wymore, R.. AU - Wymore, R. T.. AU - Wang, Y.. AU - McKinnon, D.. AU - Dixon, J. E.. AU - Mathias, R. T.. AU - Cohen, I. S.. AU - Baldo, G. J.. PY - 1999/4/15. Y1 - 1999/4/15. N2 - 1. Guinea-pig ventricle was used in the RNase protection assays to determine which α-isoforms of the Na+-K+ pumps are present, and ventricular myocytes were used in whole cell patch clamp studies to investigate the actions of α- and β-adrenergic agonists on Na+-K+ pump current. 2. RNase protection assays showed that two isoforms of the α-subunit of the Na+-K+-ATPase are present in guinea-pig ventricle. The mRNA for the α1-isoform comprises 82% of the total pump message, the rest being the α2-isoform. 3. We have previously shown that β-adrenergic agonists affect Na+-K+ pump current (I(p) through a protein kinase A (PKA)-dependent pathway. We now show that these ...

Although endemic in parts of Latin America, studies show that it is hard to transmit Chagas disease. Research studies have estimated that for one infected human, on average, more than 1,700 bites from the diseases vector - triatomine bugs - are necessary for successful transmission to occur [5]. The figures are similar for the infection of guinea pigs, averaging 1,400 bites [5]. While those figures imply that transmission of the disease is fairly inefficient, for some communities in Latin America, Chagas disease infection prevalence exceeds 40% of the population [5]. A recent study published in the Proceedings of the Royal Society B suggests that guinea pigs may be the culprit for the high rates of endemicity - at least in Arequipa, Peru [5]. Overview of Chagas Disease. According to the World Health Organization (WHO), Chagas disease is endemic in 21 Latin American countries, but its geographic breadth is spreading quickly [1]. In recent years, the disease has been detected in the United ...

The effect of specific antigen on the development of physical interactions between lymph node lymphocytes (LNL) obtained from animals which had been immunized to that antigen and macrophages was examined. We found that the presence of antigen, either limited to the macrophage () or free in the medium, profoundly increased the degree of ) or free in the medium, profoundly increased the degree of Mphi-LNL interaction observed. This enhanced interaction was dependent on the coincidence in the cultures of Mphi bearing antigen and LNL from animals specifically immunized to that antigen. Although antigen-independent interactions developed equally well between syngeneic and allogeneic combinations of lymphocytes and macrophages, antigen mediated interactions required that macrophages and lymphocytes be syngeneic. Prolongation of antigen-mediated Mphi-LNL interactions resulted in the induction of LNL DNA synthesis, initially involving those lymphocytes physically associated with antigen-bearing Mphi. ...

UO prohibits discrimination on the basis of race, color, sex, national or ethnic origin, age, religion, marital status, disability, veteran status, sexual orientation, gender identity, and gender expression in all programs, activities and employment practices as required by Title IX, other applicable laws, and policies. Retaliation is prohibited by UO policy. Questions may be referred to the Title IX Coordinator, Office of Affirmative Action and Equal Opportunity, or to the Office for Civil Rights. Contact information, related policies, and complaint procedures are listed on the statement of non-discrimination. ...

TY - JOUR. T1 - Intact B-cell activity is essential for complete expression of experimental allergic encephalomyelitis in Lewis rats. AU - Gausas, J.. AU - Paterson, P. Y.. AU - Day, E. D.. AU - Dal Canto, M. C.. PY - 1982/9/15. Y1 - 1982/9/15. N2 - B-Cell activity in weanling Lewis rats was inhibited by injections of goat anti-rat mu-chain antiserum (GAMS) from birth on, as demonstrated by markedly reduced or absent myelin basic protein (MBP) binding activity of sera. Following challenge with guinea pig spinal cord (GPSC)-complete Freunds adjuvant (CFA) and continued GAMS treatment, all rats remained clinically well without a trace of neurological signs. Histopathologically, central nervous system (CNS) perivascular fibrin deposits, typically accompanying paralytic signs of the disease, were virtually absent in GAMS-treated rats, despite occurrence of perivascular cell infiltrates of variable degrees of severity. In addition, preliminary studies of plastic embedded tissues suggest that ...

The study was designed to clarify whether captopril, an angiotensin-converting enzyme inhibitor, will reduce the injury of global ischaemia and reperfusion after cardioplegic arrest in isolated guinea pig hearts, in a modified Langendorff model. The hearts were randomly allocated into four groups (n = 10 in each) and subjected to 90 min of normothermic global ischaemia, followed by 30 min of reperfusion; in all groups, cardioplegic arrest was achieved by administering St. Thomass Hospital cardioplegic solution (STHCS). The first group was utilized as the control group. In the second group, captopril (200 mu mol/L) was added to STHCS. In the third group, oral pretreatment was carried out (0.3 mg/kg captopril was given twice a day for 10 days). In the fourth group, oral pretreatment was achieved and captopril-enriched solution was applied in the first 5 min of reperfusion. Although the study groups showed better recovery of contractility than the control group, in the fourth group the hearts had ...

Mechanisms underlying nutrient-induced segmentation within the gut are not well understood. We have shown that decanoic acid and some amino acids indu

The names tend to be cute and affectionate in nature, so perhaps think about your favorite sweet treat and use that as a name. They attended UNC-Chapel Hill. Ive also listed some guinea pig pair names at the bottom of the page. Cutest Ghostbuster in town, Trihey wrote in the Instagram post that featured the video. 45 Best Halloween Jokes for the Whole Family, The *Perfect* Halloween Instagram Captions to Try. Dress em up in a cap and gown to show off their scholarly side. Females are the fairer of the two sexes, and a girl name is perfect for a guinea pig that is shy or especially sweet. (Watch Video), Extremely disturbing: Montana woman gets 50 years in prison for selling 5-year-old girl for sex, Man Who Called March 2020 Crash Has New Prediction. U.S. election: Who was the worst president in Americas history? if not, then here are a few suggestions that will allow you to get your pet involved in the naming process. Id like to thank all our visitors who have sent us name suggestions for ...

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When deciding on where to place your outdoor guinea pig hutch you must make a few consideration. Follow our tips and advice on position your guinea pig hutch.

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The Guinea Pig Club was formed in 1941 to support aircrew who were undergoing reconstructive plastic surgery after receiving burn injuries in the Second World War. Visit our Guinea Pig Club site.

Bringing home a new guinea pig is a fun time. Make sure you have the right items on hand with this guinea pig supplies checklist.