Transgenic analysis of Dlx regulation in fish tooth development reveals evolutionary retention of enhancer function despite organ loss Journal Article ...
Fingerprint Dive into the research topics of Suppressors of Hedgehog signaling: Linking aberrant development of neural progenitors and tumorigenesis. Together they form a unique fingerprint. ...
GENSCAN predictions and expression of predicted genes: GENSCAN predicted a total of 135 genes to lie within the 760 kb of sequence analyzed. Of these, 17 correspond to genes that have previously been characterized and another 22 are at least partially homologous to mobile genetic elements such as transposons and retroviruses (Table 5). To test these gene predictions and to determine the expression patterns of predicted genes, probes were designed for 121 known and predicted genes, and developmental Northern blots containing mRNA from six different stages and tissues were probed. The chosen stages reflect most of the fly life cycle plus isolated ovaries. In total, these experiments allowed us to determine the expression pattern for an additional 64 of the 96 potential new transcription units (in addition to the previously published ones and the mobile elements). GENSCAN predictions, the autoradiographs of Northern blots, and a summary table of their developmental expression profile can be seen on ...
How is self renewal and differentiation precisely balanced to accommodate growth? Unlike the externally developing zebrafish embryo, amniotes such as mice and chickens undergo vast amounts of growth concomitantly with the formation of the embryonic body axis. The posterior body of the mouse embryo increases by approximately 65 times its initial volume during somitogenesis, this is…
Mechanisms that direct human development from conception to birth. Conserved molecular and cellular pathways regulate tissue and organ development; errors in these pathways result in congenital anomalies and human diseases. Topics: molecules regulating development, cell induction, developmental gene regulation, cell migration, programmed cell death, pattern formation, stem cells, cell lineage, and development of major organ systems. Emphasis on links between development and clinically significant topics including infertility, assisted reproductive technologies, contraception, prenatal diagnosis, multiparity, teratogenesis, inherited birth defects, fetal therapy, adolescence, cancer, and aging ...
Transcriptional regulation is achieved by the coordinated interplay of numerous protein factors with regulatory control sequences coded in the genome. At present, many of the major components of the machinery regulating transcription in eukaryotes are well known. However, mechanisms by which this complex machinery achieves precise control of cell and tissue-specific programs of gene expression observed in multi-cellular organisms is poorly understood. Our laboratory is interested in deciphering mechanisms of gene expression patterns critical for proper organ development and function in mammals. Using the mouse as a rich genetic and developmental system, we plan to probe the biological function of various components of the transcriptional apparatus to uncover novel pathways of cell type specification. In addition to characterizing basic mechanisms of differentiation and development, we will utilize developmental defects in the mouse to model human disease states as potential avenues of ...
A previously unknown oncogenic feature of an embryonic transcription factor was uncovered from transcriptomic analysis of tumors that lack functional Polycomb silencing.
each of the following were suppose to be rounded to two sig figs. mark then correct or incorrect. if incorrect state the correct answer 1) 1.249 103 to 1.3 103 i know its wrong but i dont know the correct answer 2)7.999 102 to 80 ...
Some days ago, I had a talk with a colleague from another development organization about web2fordev. We were asking whether web2.0 can...
Spatial expression pattern of MBC in wild-type embryos. Anterior is to the left and dorsal to the top in all except A. (A) Stage 13 embryos from the progeny of
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These OVE#2489A mice harbor a mutation created by random insertion of the SB-sa-IRES-rtTA-pA-SB-Tyro-WPRE-FUGW lentiposon transgene (LV2223). The donating investigator reports the phenotype of homozygous mice as: embryonic day (E)8 lethal.
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J:122405 Kemp CR, Willems E, Wawrzak D, Hendrickx M, Agbor Agbor T, Leyns L, Expression of Frizzled5, Frizzled7, and Frizzled10 during early mouse development and interactions with canonical Wnt signaling. Dev Dyn. 2007 Jul;236(7):2011-9 ...
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Avhandlingar om DEVELOPMENTAL STAGES. Sök bland 78317 avhandlingar från svenska högskolor och universitet på Avhandlingar.se.
Returns the number of columns occupied by this cell accessible. This is 1 if the specified cell is only in one column, or more than 1 if the specified cell spans multiple columns. ...
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