TY - JOUR. T1 - Diagnostic challenge of hyper-IgD syndrome in four children with inflammatory gastrointestinal complaints. AU - Oretti, Chiara. AU - Barbi, Egidio. AU - Marchetti, Federico. AU - Lepore, Loredana. AU - Ventura, Alessandro. AU - DOsualdo, Andrea. AU - Gattorno, Marco. AU - Martelossi, Stefano. AU - Tommasini, Alberto. PY - 2006/3. Y1 - 2006/3. N2 - Objective. Hyper-IgD syndrome (HIDS) is a rare autosomal recessive disease characterized by recurrent fever, lymphadenopathy, diarrhoea, abdominal pain, headache, arthralgia and skin rash. Abdominal symptomatology may mimic inflammatory bowel disease. We report on four patients with HIDS who had been previously investigated for Crohns disease (CD). The levels of IgD were measured in a series of patients with CD to evaluate the specificity of this assay in the differential diagnosis between the two conditions. Material and methods. Diagnosis of HIDS was based on clinical criteria as well as immunological or genetic data. IgD levels ...

Balchaturbhadrika Syrup, For Children by Dhootapapeshwar is a syrup for good health of children and babies. It treats respiratory problems like cold, cough, asthma and gastrointestinal problems. It boosts immunity of the child and helps them in fighting bacterias and infections. It also treats vomiting and diarrhea. Children are very susceptible to bacteria and viruses and fall sick easily as their immune system is weak and not fully developed. This syrup helps children build a strong immune system and treats already facing respiratory and gastrointestinal problems. It also increases growth in children who are facing problems with growth. This product contains all natural ingredients with no side effects and hence is very safe to give to children. Active Ingredients Nagarmotha (Cyperus rotundus): Nagarmotha has carminative, analgesic, anti-inflammatory and diuretic properties. It is used to treat viral fever, asthma, skin conditions like eczema, gastrointestinal problems like constipation and ...

BACKGROUND: Abdominal pain-predominant functional gastrointestinal disorders (AP-FGIDs) are a common public health problem in children. The precise aetiology of AP-FGIDs is far from clear. Psychological stress and all forms of child abuse are known predisposing factors to develop AP-FGIDs. The main objective of this study is to study the association between adverse life events (ALEs) and development of AP-FGIDs. METHODS: A cross sectional, school based study was conducted in Gampaha district of Sri Lanka. All children aged 13-18 years were recruited from four randomly selected semi-urban schools in the district after obtaining consent from parents, school administration and children themselves. A translated and validated, self-administered questionnaire consisting of four parts was used for data collection. Part I was the Rome III questionnaire for functional gastrointestinal disorders, self-report form for children above 10 years. Part II was a questionnaire on exposure to adverse life events. ...

Postoperative gastrointestinal dysfunction (PGD) is a common complication following laparotomy under general anesthesia (GA). Abdominal distension occurs in 8-28% of surgeries within 24 h postoperatively. The present study aimed to analyze the efficacy of electroacupuncture (EA) for the prevention of PGD by applying preoperative EA stimulation of PC6 (Neiguan), ST36 (Zusanli), and ST37 (Shangjuxv) bilaterally twice within 24 h prior to surgery, compared with no acupuncture treatment. The study participants were assessed and selected from participants undergoing vascular laparotomy under GA at the Liver and Vascular Surgery Unit in West China Hospital of Sichuan University. The selected participants were randomly allocated to two groups: routine-treatment (RT) and EA group receiving EA at PC6, ST36, and ST37. A computer-generated list of random numbers was used to determine the allocation of the participants, with numbered opaque sealed envelopes containing the randomization schedule. Eligible

TY - JOUR. T1 - Dissociation of analgesic and gastrointestinal effects of electroconvulsive shock-released opioids. AU - Galligan, James J.. AU - Porreca, Frank. AU - Burks, Thomas F.. PY - 1983/7/25. Y1 - 1983/7/25. N2 - Activation of endogenous opioid systems by electroconvulsive shock (ECS) produced naloxone-reversible thermal analgesia (52 °C hot plate) 5 min after ECS administration. Although pioid peptides injected intracerebroventricularly have previously been found to inhibit gastrointestinal motility, ECS treatment did not affect gastric emptying, small or large intestinal transit. These results suggest that centrally-mediated opioid analgesia and changes in gastrointestinal motility are initiated through independent mechanisms.. AB - Activation of endogenous opioid systems by electroconvulsive shock (ECS) produced naloxone-reversible thermal analgesia (52 °C hot plate) 5 min after ECS administration. Although pioid peptides injected intracerebroventricularly have previously been ...

BACKGROUND/AIMS Functional gastrointestinal disorders (FGID) affect 15%-20% of the general pediatric and adult population. Animal models suggest that a neonatal stress such as invasive procedures and maternal separation could be responsible for visceral hypersensitivity and FGID. We tested the hypothesis that congenital esophageal atresia (EA), a condition corrected during the neonatal period and associated with multiple stresses, is a clinically significant risk factor for the development of FGID later in life. We postulated that, to be clinically significant, the effect of neonatal stress on the incidence of FGID should be as strong as that of enteric infections in the development of irritable bowel syndrome in children. METHODS Subjects with EA and healthy controls were enrolled in this multicenter cohort study. Gastrointestinal symptoms were assessed by a questionnaire and FGID was diagnosed using the Rome III criteria. RESULTS Fifty-three children (25 girls; median age, 12 years) with EA were

Dyspepsia is a common problem in the community and clinical practice with symptom(s) considered arising from the gastroduodenal region. Dyspepsia burden and associated factors vary from country to country. The aim of this study was to determine the prevalence of uninvestigated dyspepsia (UD) using Rome III criteria, associated risk factors and self-reported dyspepsia symptoms correlation with H. pylori infection. A cross-sectional study was conducted among randomly selected 318 out patients with gastrointestinal complaints during the period from September 1 to December 30, 2015. All patients completed a questionnaire for collecting data regarding sociodemographic, lifestyle and functional gastrointestinal disorders. Diagnosis of dyspepsia was made according to the Rome III criteria. H. pylori infection was assessed using stool antigen test. SPSS version 20.0 statistical software package was used for data analysis. From a total of 318 patients, 48.4% had UD according to Rome III criteria; with 42.1%

INTRODUCTION Abdominal pain predominant functional gastrointestinal disorders (AP-FGIDs) are common among Sri Lankan adolescents and teenagers and it is an important healthcare problem. However, studies are rarely conducted to determine the prevalence and clinical profile of AP-FGIDs in 5-12-year age group. METHODS A cross sectional survey was conducted in four randomly selected schools in Gamapaha district of Sri Lanka. All children aged 5-12 years were recruited after obtaining parental consent. Data was collected using a translated and validated parental questionnaire. AP-FGIDs were diagnosed using Rome III criteria. RESULTS A total of 1000 questionnaires were distributed and 709 (70.9%) returned. Properly filled 653 questionnaires were included in analysis [309 (47.3%) boys. mean age 8.8 years (SD 1.9 years)]. Eighty-two (12.6%) fulfilled criteria for the AP-FGIDs. Prevalence of AP-FGIDs was higher in females than male (7.9% vs. 4.5%, p=0.037, Chi-square test). Thirty-two (4.9%) had FAP, 26 ...

Althaeae radix Marshmallow root Althaea officinalis L. Published 2019 Format: PDF Online viewing (for only €30 per year, you can view online all the monographs) Summary The herbal monograph selects and summarizes scientific studies and textbooks regarding efficacy, dosage and safety … [Read more...] about Althaeae radix (Marshmallow Root) ...

Although aging has relatively minimal effects on GI function, age-related changes can cause or contribute to several GI disorders. For example, oral changes (e.g., decreased taste sensation, decreased saliva production) can cause poor appetite, with associated weight loss. Aging can result in impaired function of the gastric mucosal barrier and increased risk of peptic ulcer disease. Patients residing in long term care facilities typically have numerous concurrent conditions and use numerous medications that may complicate the assessment and treatment of GI disorders. GI disorders may also be caused or exacerbated by a variety of medical conditions that are more prevalent with age. Fecal impaction and dehydration are sentinel events that may indicate a patient has or is at high risk for a GI disorder. In addition, the presentation of many GI disorders in older people is atypical. For example, GERD may present as dysphagia, asthma, recurrent aspiration pneumonia, or even cough. It is important ...

What most people ponder of as a dog food allergy is more appropriately called an cutaneous adverse food reaction, or CAFR,» says Dr. Justin Shmalberg, a DVM and NomNomNows own veterinary nutritionist. «It basically means theres some association between a food and a certain group of symptoms-usually skin problems or gastrointestinal problems.». In a true dog food allergy, according to Shmalberg, the culprit is often a food protein that triggers an adverse immune response, which then causes cells in the body to release histamines, or compounds that lead to itching and numerous other allergic signs.. A dog food intolerance, on the other hand, doesnt involve an immune response-but the signs of dog food intolerance can glance beautiful similar to the signs of a food allergy.. One example is a lactose intolerance, which happens when a dogs body just doesnt process lactose in milk products well, leading to gastrointestinal problems (often diarrhea).. Both allergies and intolerances drop under ...

People with lupus may also have secondary Sjogrens, which is another autoimmune disorder that overlaps with lupus. Symptoms include dry eyes and mouth, vaginal dryness, joint pain and swelling, gastrointestinal problems, oral ulcers, eye and mouth infections, and it can also affect the lungs, liver, kidneys, skin and nervous system. There are two types of Sjogrens: Primary Sjogrens, which occurs on its own without any other illnesses, and Secondary Sjogrens, which is what affects people with other similar illnesses such as lupus or rheumatoid arthritis. Both types of Sjogrens produces the same symptoms. Symptoms include dry eyes and mouth, vaginal dryness, joint pain and swelling, gastrointestinal problems, oral ulcers, eye and mouth infections, and it can also affect the lungs, liver, kidneys, skin and nervous system. ...

Thus far, three types of weapons of mass destruction (WMDs) (i.e., nuclear weapons, chemical weapons and biological weapons), have been developed. Although there are international treaties that prohibit the development, stockpiling and use of WMDs, the ghost of WMDs has still occasionally appeared during wars in recent decades. For example, the United States bombed Japan with nuclear weapons [51] during World War II. Additionally, data revealed that Unit 731 of the Imperial Japanese Army, known as the Epidemic Prevention and Water Purification Department during World War II, conducted germ warfare attacks [52] in China. The Gulf War was launched by the United States and its allies based on the suspicion that the Iraqi government had its WMD programs. Finally, no evidence of WMDs was found in Iraq after the war. However, during that war, depleted uranium bombs were applied which contained radioactive uranium. Some believed that depleted uranium bombs were not nuclear weapons, and thus the ...

If your baby seems fussy and youve fed and changed him, he may have an upset stomach or colic. But dont worry, there are lots of things you can do to make your little one more comfortable and keep both of you calm.

Cows milk allergy (CMA) is the most common food allergy in early childhood, with an estimated incidence ranging between 2% and 3% in infants and marginally lower in older children. It has been demonstrated that it could be a risk factor for the development of the functional gastrointestinal disorders in children. Intestinal microflora has been indicated as potential target for the management of CMA and FGDIs through the use of probiotics. Lactobacillus rhamnosus GG (LGG) is the most studied probiotic. Recently, it has been demonstrated that an extensively hydrolyzed casein formula remains hypoallergenic following the addition of LGG, satisfying both the American Academy of Pediatrics guidelines. Lactobacillus GG exerts several benefits when added to an extensively hydrolyzed casein formula (Nutramigen LGG), including decreased severity of atopic dermatitis, improved recovery of intestinal symptoms in infants with CMA-induced allergic colitis, and faster induction of tolerance in infants with ...

misc{8892516, abstract = {The physicochemical properties of oat β-glucan have been shown to govern its health benefits by a plethora of studies. However, the effect of the passage through the gastrointestinal tract on the conformational and structural characteristics is not fully explained. The aim of the present study was to elucidate the effect of in vitro gastrointestinal conditions on the structure and conformation of oat β-glucan utilizing Asymmetric Flow Field-Flow Fractionation (AF4) coupled with multiple detectors and in conjunction with NMR. Oat β-glucan was gently extracted from oat flour and its conformational characteristics before and after in vitro gastric and gastrointestinal digestion was investigated with AF4. The contribution of digestive enzymes and bile acids on the conformation of β-glucan was also explored. Moreover, the structural features and the bile acid-binding capacity of oat β-glucan were analyzed with NMR spectroscopy. Oat β-glucan without digestion presented ...

This study was a comparison of the prevalence of infectious gastrointestinal disease and the quality of construction of individual, surface source water systems in Lincoln County, Oregon. Two measurement instruments were developed for this study. An objective instrument was developed to determine if the water systems observed in the study were adequately or inadequately constructed. A second objective instrument was developed to determine if individuals interviewed in the study were ill with an infectious gastrointestinal disease. The Delphi Method was used to validate the two instruments, and was based on a concensus of opinions by a panel of experts regarding this subject matter. The sample population was identified through a systematic selection of dwellings using a Lincoln County Department of Engineers road map and a list of random numbers. Individuals were interviewed using the Surface Source Water System Gastrointestinal Disease Evaluation instrument to determine if they had an infectious ...

Autism spectrum disorders (ASDs) are common and clinically heterogeneous neurodevelopmental disorders. Gastrointestinal disorders and associated symptoms are commonly reported in individuals with ASDs, but key issues such as the prevalence and best treatment of these conditions are incompletely understood. A central difficulty in recognizing and characterizing gastrointestinal dysfunction with ASDs is the communication difficulties experienced by many affected individuals. A multidisciplinary panel reviewed the medical literature with the aim of generating evidence-based recommendations for diagnostic evaluation and management of gastrointestinal problems in this patient population. The panel concluded that evidence-based recommendations are not yet available. The consensus expert opinion of the panel was that individuals with ASDs deserve the same thoroughness and standard of care in the diagnostic workup and treatment of gastrointestinal concerns as should occur for patients without ASDs. Care ...

People treated for cancer when they were children have a higher-than-average risk of gastrointestinal problems some mild, some quite severe in the years following treatment, according to a study to be presented at the 42nd Congress of the International Society of Paediatric Oncology (SIOP) in Boston on Sunday, Oct. 24. Investigators at Dana-Farber/Childrens Hospital Cancer Center and their colleagues say their findings suggest that childhood cancer survivors and their physicians should be especially aware of the increased likelihood of gastrointestinal troubles and factor them into plans for monitoring survivors health.. Current treatments have dramatically increased survival rates for children with cancer, but we know that many cancer therapies including surgery, radiation, and chemotherapy can cause significant gastrointestinal [GI] complications for patients, says the studys senior author, Lisa Diller, MD, director of the Perini Family Survivors Center at Dana-Farber. Little ...

From MSDS: Principal Hazards Warning -Accidental ingestion of a small amount of this material may cause gastrointestinal disturbances including irritation, nausea, vomiting and diarrhea. A very large ingestion could result in fatigue, dizziness, coma, respiratory arrest and death. Chemical pneumonitis or non-cardiogenic pulmonary edema can also develop. -This material is an aspiration hazard; product can enter the lungs during swallowing or vomiting and cause lung damage. -Maybe irritating to the eyes, skin and respiratory tract. -Breathing vapors may cause harmful central nervous system effects including, dizziness, drowsiness, blurred vision, loss of consciousness and death. -Combustible liquid. Product may present a moderate fire and explosion hazard. -May cause chronic health effects. Oral Toxicity: May cause gastrointestinal disturbances including irritation, abdominal pain, belching, nausea, vomiting, frequent loose stools and diarrhea. Ingestion of large quantities may cause harmful ...

The incidence of common adverse reactions (above 1%) was obtained from a population of 835 ketoprofen-treated patients in double-blind trials lasting from 4 to 54 weeks and in 622 patients treated with ketoprofen extended-release capsules in trials lasting from 4 to 16 weeks.. Minor gastrointestinal side effects predominated; upper gastrointestinal symptoms were more common than lower gastrointestinal symptoms. In crossover trials in 321 patients with rheumatoid arthritis or osteoarthritis, there was no difference in either upper or lower gastrointestinal symptoms between patients treated with 200 mg of ketoprofen extended-release capsules once a day or 75 mg of ketoprofen immediate-release capsules TID (255 mg/day). Peptic ulcer or GI bleeding occurred in controlled clinical trials in less than 1% of 1,076 patients; however, in open label continuation studies in 1,292 patients, the rate was greater than 2%.. The incidence of peptic ulceration in patients on NSAIDs is dependent on many risk ...

ABSTRACT. Introduction. Amyloidosis is a rare disease associated with extracellular accumulation of abnormal protein - amyloid in various organs and systems. This disease can be either acquired or hereditary, systemic or localized. At its core, it represents a grown, tumor-like neoplastic clone of the plasma cells in the bone marrow. Gastrointestinal amyloidosis is manifested by symptoms, such as diarrhea, steatorrhea, constipation, and very rarely - hemorrhages and perforations of the colon.. Case presentation. We present a case of primary intestinal amyloidosis with recurrent hematochezia and abdominal pain in a 61-year-old woman. Colonoscopy revealed polyposis of the whole colon and a total colectomy was performed, followed by morphological and paraclinical examinations. Histologically, amyloid deposition, positive for Congo red, was found in the walls of the submucosal blood vessels and in the smooth muscle cells of the muscular layers. The laboratory tests indicated anemia, high erythrocyte ...

Free, official information about 2009 (and also 2010-2015) ICD-9-CM diagnosis code 277.03, including coding notes, detailed descriptions, index cross-references and ICD-10-CM conversion.

At Digestive & Liver Disease Consultants, PA, we offer comprehensive care for an extensive range of gastrointestinal problems ‒ from the simple to the complex. The gastroenterologists provide patients with comprehensive screening, diagnosis and treatment plans with access to advanced procedures and innovative technology at Humble , Kingwood, Woodlands, Conroe, Northwest Houston

A Gastroenterologist must first complete a three-year Internal Medicine residency and is then eligible for additional specialized training (fellowship) in Gastroenterology. This fellowship is generally 2-3 years long so by the time Gastroenterologists have completed their training, they have had 5-6 years of additional specialized education following medical school.. Gastroenterology fellowship training is an intense, rigorous program where future Gastroenterologists learn directly from nationally recognized experts in the field and develop a detailed understanding of gastrointestinal diseases. They learn how to evaluate patients with gastrointestinal complaints, treat a broad range of conditions, and provide recommendations to maintain health and prevent disease. They learn to care for patients in the office as well as in the hospital. Gastroenterologists also receive dedicated training in endoscopy (upper endoscopy, sigmoidoscopy, and colonoscopy) by expert instructors. Endoscopy is the use of ...

Special clinical interests : Inflammatory Bowel Diseases, gastrointestinal bleeding, peptic ulcer disease, anaemia, gastrointestinal problems caused by diseases in other body systems, gastrointestinal infections including C. difficile, gastrointestinal hormones, oesophageal diseases including Barretts oesophagus and achalasia, teaching and training. Research interests : Barretts oesophagus and oesophageal cancer, management of inflammatory bowel diseases and gastrointestinal bleeding, anaemia in gastrointestinal diseases, microscopic colitis, H pylori, C difficile, diverticulitis and gastrointestinal hormones.. Telephone: 01603 288859 Secretary: Ruth Mackay - [email protected] - ext 4366. Direct line 01603 288366. GMC number: 3407466. Current membership(s) of professional National and Regional bodies: Training Programme Director and Head of Speciality Training, East of England Gastroenterology Training Scheme, Head of Specialist Training for East of England, Member of National Specialist ...

Title:Recent Advances in Probiotics as Live Biotherapeutics Against Gastrointestinal Diseases. VOLUME: 24 ISSUE: 27. Author(s):Rohini Krishna Kota, Ranga Rao Ambati*, Aswani Kumar Y.V.V., Krupanidhi Srirama and Prakash Narayana Reddy*. Affiliation:Department of Biotechnology, Vignans Foundation for Science, Technology and Research, Vadlamudi, Guntur-522213, Andhra Pradesh, Department of Biotechnology, Vignans Foundation for Science, Technology and Research, Vadlamudi, Guntur-522213, Andhra Pradesh, Department of Biotechnology, Acharya Nagarjuna University Nagarjuna Nagar, Guntur- 522510, Andhra Pradesh, Department of Biotechnology, Vignans Foundation for Science, Technology and Research, Vadlamudi, Guntur-522213, Andhra Pradesh, Department of Biotechnology, Vignans Foundation for Science, Technology and Research, Vadlamudi, Guntur-522213, Andhra Pradesh. Keywords:Gastrointestinal diseases, therapy, probiotics, biotherapeutics, Fecal Microbial Transplants (FMTs), Gut microbiota ...

Goldsboro, NC Gastroenterologist, Digestive Disease Center, P.A.. Treating stomach pain, intestinal problems, acid reflux, constipation and other gastrointestinal problems.

Integrative medicine in gastrointestinal disease: evaluating the evidence.: Current Western therapies for many gastrointestinal diseases are suboptimal and pote

Gastroesophageal Reflux Disease is actual problem among the population with gastrointestinal complaints. According to statistics in Russia, it is about 40-50% from all gastrointestinal diseases. GERD elapses with heartburn, which arises because of reflux of bile and gastric contents into the esophag

Gastrointestinal disturbances are commonly reported in children with autism, complicate clinical management, and may contribute to behavioral impairment. Reports of deficiencies in disaccharidase enzymatic activity and of beneficial responses to probiotic and dietary therapies led us to survey gene expression and the mucoepithelial microbiota in intestinal biopsies from children with autism and gastrointestinal disease and children with gastrointestinal disease alone. Ileal transcripts encoding disaccharidases and hexose transporters were deficient in children with autism, indicating impairment of the primary pathway for carbohydrate digestion and transport in enterocytes. Deficient expression of these enzymes and transporters was associated with expression of the intestinal transcription factor, CDX2. Metagenomic analysis of intestinal bacteria revealed compositional dysbiosis manifest as decreases in Bacteroidetes, increases in the ratio of Firmicutes to Bacteroidetes, and increases in

For many years, there has been limited interest within the medical field in how the brain and gut interact in health and disease. Even patients with common functional GI disorders such as irritable bowel syndrome (IBS), functional dyspepsia and functional heartburn were reluctant to accept such a concept, wrongly assuming their symptoms would be explained in psychological terms. The emerging research into the gut microbiome has dramatically changed the equation in the last five years, with the study of brain-gut microbiome (BGM) interactions taking center stage in many fields and specialties, including gastroenterology, cardiology, chronic pain and psychiatry, to name only a few.

Each patient developed severe neuropathic pain within 8 weeks of initiating intensive glycemic control. Nine patients (age range, 19-29) had type 1 diabetes, and 7 patients (age range, 31-58) had type 2 diabetes. Other common causes of neuropathy were ruled out. Average glycosylated hemoglobin levels were about 14% before intensive glycemic control and about 7% afterward. Pain was in a stocking-glove distribution in 13 patients and was diffuse in 3 patients. Autonomic symptoms (e.g., orthostatic hypotension, gastrointestinal dysfunction) occurred commonly, and standardized tests of sympathetic and parasympathetic function were abnormal in most patients. Retinopathy also worsened during the first 6 months of sustained glycemic control. Pain subsided eventually in most patients, but only after 1 to 2 years of combination drug therapies for neuropathic pain ...

Aloe Vera is recognized for its remarkable health-enhancing virtues. Although, used as a common home remedy for treating external skin problems such as minor burns and skin cuts, Aloe plant is now widely used to help treat a variety of digestive conditions. Scientific research suggests that amino acids, enzymes, vitamins and minerals present in the Aloe Vera plant aid in improving digestive health.. Aloe Vera has natural healing and detoxifying powers that work gently within the body to break down food particles and completely cleanse the bowel. It is also known to prevent diarrhoea, ease constipation, reduce bloating and stomach discomfort. Bioconcepts Aloe Vera Capsules are made from the finest ingredients containing Aloe Vera, fennel and pectin powder. These capsules mimic the healing properties of Aloe Vera and may help you to ease gastrointestinal problems.. ...

Purchase Gastrointestinal Pathology: Common Questions and Diagnostic Dilemmas, An Issue of Surgical Pathology Clinics, Volume 10-4 - 1st Edition. Print Book & E-Book. ISBN 9780323553025, 9780323553032

Dr. Narendra Siddaiah, MD is a Gastroenterologist in Silverdale, WA. Treating stomach pain, intestinal problems, acid reflux, constipation and other gastrointestinal problems.

A systematic review of 70 studies investigating the use of probiotics in the management of lower gastrointestinal symptoms (IBS, antibiotic-associated diarrhoea, diarrhoea associated with Helicobacter pylori eradication therapy and other conditions) was performed, evidence was graded and recommendations for the physicians provided. Specific probiotics are beneficial in (i) reduction of total symptoms and abdominal pain …. Probiotics in the management of lower gastrointestinal symptoms Read More ». ...

AIM: To study the different endocrine cell types in the oxyntic mucosa of patients with irritable bowel syndrome (IBS).. METHODS: Seventy-six patients with IBS were included in the study (62 females and 14 males; mean age 32 years, range 18-55 years), of which 40 also fulfilled the Rome III criteria for functional dyspepsia (FDP). Of the entire IBS cohort, 26 had diarrhea as the predominant symptom (IBS-D), 21 had a mixture of diarrhea and constipation (IBS-M), and 29 had constipation as the predominant symptom (IBS-C). Forty-three age and sex-matched healthy volunteers without any gastrointestinal complaints served as controls. The patients were asked to complete the Birmingham IBS symptom questionnaire. Both the patients and controls underwent a standard gastroscopy, during which three biopsy samples were taken from the corpus. Sections from these biopsy samples were immunostained using the avidin-biotin complex (ABC) method, for ghrelin, serotonin, somatostatin and histamine. The densities of ...

Gastrointestinal (GI) disorders represent some of the most frequent complaints during pregnancy. Some women have GI disorders that are unique to pregnancy.

Methodology was developed to measure the glycoprotein content of the whole stomach as an index of changes in the gastric mucus. Indomethacin significantly reduced the glycoprotein content of the stomach, whilst calcitonin reversed this reduction to near normal levels and carbenoxolone sodium to significantly higher than normal levels. Despite this reversal, carbenoxolone sodium failed to reduce the ulceration produced by indomethacin. In contrast, calcitonin significantly inhibited the indomethacin-induced ulceration. An increase in mucus production alone is therefore insufficient to account for the anti-ulcerogenic effect observed ...

TY - JOUR. T1 - Struktura chemiczna lipopolisacharydu Helicobacter pylori a wrodzona odpowiedź immunologiczna. AU - Arabski, Michał. AU - Koza, Anna. AU - Kaca, Wiesław. PY - 2008. Y1 - 2008. N2 - H. pylori is a causative agent of chronic gastritis. Gastrointestinal disorders are associated with a bacterial mechanism of adaptation to the stomachs environment and the immune responses of gastric epithelial cells. The efficacy of H. pylori lipopolysaccharides identify cation by host cells is determined by their chemical structure. This paper focuses mainly on the molecular mechanisms of innate immune evasion by H. pylori, the Toll-like receptor 2/4 activity of epithelial and immune system cells, and molecular mimicry (Lewis antigen).. AB - H. pylori is a causative agent of chronic gastritis. Gastrointestinal disorders are associated with a bacterial mechanism of adaptation to the stomachs environment and the immune responses of gastric epithelial cells. The efficacy of H. pylori ...

Dr. Robert Fusco is a Gastroenterologist in Moon, PA. Treating stomach pain, intestinal problems, acid reflux, constipation and other gastrointestinal problems.

Dr. Robert Fusco is a Gastroenterologist in Moon, PA. Treating stomach pain, intestinal problems, acid reflux, constipation and other gastrointestinal problems.

Results Faecal calprotectin was requested in 2 groups of patients: 68 with lower gastrointestinal symptoms and 44 with Inflammatory Bowel Disease (IBD). Of the 68 patients with lower gastrointestinal symptoms, faecal calprotectin was normal in 48 patients: 13 (9 males, 4 females, median age 30 years, commonest symptom abdominal pain) at initial presentation had no further investigation, 23 (11 males, 12 females, median age 41, commonest symptom abdominal pain) went onto have further investigations (12 colonoscopies, 3 flexible sigmoidoscopies and 1 small bowel meal and follow through; all normal); in 12(3 males, 9 females, median age 45, commonest symptom chronic diarrhoea) the negative faecal calprotectin was as a second line following initial investigation including 8 normal colonoscopies and 1 normal flexible sigmoidoscopy. Of those patients with IBD, faecal calprotectin was normal in 9 patients. In 7 patients management decisions were taken on the basis of its result alone. These included ...

The investigators found that patients who started treatment with non-aspirin NSAIDs were at greater risk of experiencing atrial fibrillation or flutter when compared with patients who did not use NSAIDs. The increased risk differed depending on the drugs used: there was about a 40 percent increased risk for those who used non-selective NSAIDs and 70 percent among those who used COX-2 inhibitors. The research team, led by Professor Henrik Toft Sorensen at Aarhus University Hospital in Denmark, also identified certain groups at greatest risk for atrial fibrillation in the study. They included older people and patients with chronic kidney disease or rheumatoid arthritis who started treatment with COX-2 inhibitors. Both non-selective NSAIDS and COX-2 inhibitors have been associated with a number of side effects (e.g., gastrointestinal problems) and serious long-term risks, including an increased chance of a stroke and heart attack. Atrial fibrillation has been linked to risks as well, including ...

Copyright 2013 by the Massachusetts General Hospital. Some sections copyright 2008-2009 by The President and Fellows of Harvard College.. ...

Singh said its plausible that hiccups could be a sign of COVID-19 for some patients, based on what we know about how the virus and digestive system interact.. Research has shown that the virus can lead to gastrointestinal problems: One study found that of 204 patients with COVID-19, 103 reported some kind of gastrointestinal symptom. The most common were diarrhea and loss of appetite. Six of those patients had no respiratory symptoms at all - only gastrointestinal ones. A CDC study, similarly, found that approximately half of patients had gastrointestinal symptoms, including diarrhea and vomiting. If the coronavirus irritates the gastrointestinal tract, it may also impact the phrenic nerve, which controls the diaphragm. An irritated phrenic nerve can cause involuntary contractions of the diaphragm - also known as hiccups. Anytime the GI tract is affected, its biologically plausible that you could end up with the hiccups, Lisa Maragakis, senior director of infection prevention at the Johns ...

Growth retardation in childhood may be one of the earliest signs of an underlying disease, such as coeliac disease. In the Netherlands, the growth of nearly every child is monitored. When growth is retarded, the child is referred to secondary health care. After referral it has been advised to perform a diagnostic work-up containing routine laboratory tests to search for diagnostic clues for, among others, coeliac disease. The tests presently used for coeliac disease are IgA EmA and IgA antitissue transglutaminase antibodies. The total immunoglobulin A count is determined as well, because coeliac disease is associated with IgA deficiency. It was questioned if diagnostic investigations for coeliac disease should be performed in all children with short stature, even without gastrointestinal complaints. Some studies (Knudtzon, Stenhammar, Cacciari, Cacciari, Rossi) were based on study groups, in which no preliminary (endocrine) work-up to exclude other causes for short stature had been performed. ...

Some gastrointestinal diseases can be seen and diagnosed with the naked eye, such as ulcers of the stomach. Thus, ulcers can be seen at surgery, on x-rays, and at endoscopies. Other diseases cannot be seen with the naked eye but can be seen and diagnosed with the microscope. For example, celiac disease and collagenous colitis are diagnosed by microscopic examination of biopsies of the small bowel and colon, respectively. In contrast, gastrointestinal functional diseases cannot be seen with the naked eye or with the microscope. In some instances, the abnormal function can be demonstrated by tests, for example, gastric emptying studies or antro-duodenal motility studies. However, these tests often are complex, are not widely available, and do not reliably detect the functional abnormalities. Accordingly, by default, functional gastrointestinal diseases are those involving the abnormal function of gastrointestinal organs in which abnormalities cannot be seen in the organs with either the naked eye ...

Some gastrointestinal diseases can be seen and diagnosed with the naked eye, such as ulcers of the stomach. Thus, ulcers can be seen at surgery, on x-rays, and at endoscopies. Other diseases cannot be seen with the naked eye but can be seen and diagnosed with the microscope. For example, celiac disease and collagenous colitis are diagnosed by microscopic examination of biopsies of the small bowel and colon, respectively. In contrast, gastrointestinal functional diseases cannot be seen with the naked eye or with the microscope. In some instances, the abnormal function can be demonstrated by tests, for example, gastric emptying studies or antro-duodenal motility studies. However, these tests often are complex, are not widely available, and do not reliably detect the functional abnormalities. Accordingly, by default, functional gastrointestinal diseases are those involving the abnormal function of gastrointestinal organs in which abnormalities cannot be seen in the organs with either the naked eye ...