Worldwide, gastrointestinal disorders are common complaints in the general population and must be monitored by community health care organizations [14, 15]. For this purpose, questionnaires can be very helpful because they are easy to use extensively, can gather a lot of information rapidly, and are relatively inexpensive (particularly in comparison to monthly check ups) [16-18].. In the present study, gastrointestinal complaints were reported by a very high proportion (81.9%) of shift-workers. This proportion was twice as large as that reported in a previous study in Korea [19]. This could be due to environmental factors, hospital organization, social factors, insufficient welfare facilities, inordinate hours of working or erratic shifts, or even perhaps inappropriate answers to various questionnaires. On the other hand, Scott and colleagues reported 75% of gastrointestinal complaints in night-workers [20].. In our population of nurses in Iran, the prevalence of GI symptoms was significantly ...
Gastrointestinal Disturbances are any conditions related to the dysfunction of digestion. Chinese Medicine has successfully been treating these conditions for 3,000 years. Chinese Medicine works to create harmony in the digestive tract so that your body can efficiently absorb nutrients and restore your health.. For those who suffer from gastrointestinal related disorders and who have tried conventional treatment or are seeking a natural remedy, please give Chinese Medicine an opportunity to show its strength.. Some of the many conditions Chinese Medicine treats related to Gastrointestinal Disturbances are:. -Irritable Bowels (IBS ...
Functional gastrointestinal (GI) and motility disorders are the most common GI disorders in the general population. Functional GI disorders are disorders of gut-brain interaction.
Gastrointestinal Problems - Upper Gi,Medical Illustration database of the best portfolios and stock images now features General and Commercial Illustration and illustrators. 8,000+ image database includes all types of subjects and features the largest directory of medical, science, and nature illustrators and illustration on the web.
Colic. Colic is a problem that affects some babies during the first 3 to 4 months of life. It can be very stressful and frustrating to parents. Healthcare providers have defined colic as prolonged or excessive crying in an infant who is otherwise well. The crying can be very loud and can last for several hours a day. Colic often starts by 3 weeks of age, is at its worst around 6 weeks, and gradually gets better by about 3 months of age. It is not clear what causes colic. Many people think that colic is caused by belly cramps or gas, but no one really knows for sure. Treatment for gas or changing formulas has not been shown to decrease crying in a colicky baby. Talk to your childs healthcare provider if you think there is a gastrointestinal problem making your baby fussy. Some of the reasons babies may have colic include the following: ...
Gastrointestinal problems in children with Downs syndrome by Dr Liz Marder This article was written for parents for the Down s Syndrome Association newsletter and is reproduced here with the permission
Learn what different gastrointestinal problems a newborn can have and how to treat them. For more parenting resources, visit the MoBap Childbirth Center.
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Epidemiological study on the Functional Gastrointestinal Disorders, 978-3-659-49195-5, Functional gastrointestinal disorders (FGIDs) are common in the community, are of chronic nature and pose a significant health care burden. The causes and pathogenetic mechanisms of FGIDs are not fully known. FGID are classified into three major domains: functional dyspepsia, functional bowel disorders including irritable bowel syndrome (IBS), and heartburn. The aim was to study the natural history of FGID in the Icelandic population over a 10-year period. Only one other study has been performed on FGIDs using the same methodology, in Olmsted County Minnesota, USA and thus providing the possibility of a direct comparison. Secondary objectives of the study were: 1) to compare the prevalence and stability of IBS according to the Manning criteria, Rome II, Rome III subtypes, and self-reported IBS over a 10 year period: 2) to study IBS and dysmenorrhea in women and to assess the change in IBS over menopause: 3) to study
Functional gastrointestinal disorders are common in children and adolescents with complaints of abdominal pain. Our brains and our GI tracts are closely connected (the "mind-body connection"). Functional GI conditions are due to a combination of extra sensitivity of the GI tract, with changes in the motility or movement of the digestive system. Our stomachs and intestines are moving food all the time, and some people feel this more intensely than other people. Its as if the "volume" has been turned up from their GI tract. When their brains receive these sensations, its reaction can change the motion of the GI tract. These conditions are common, sometimes run in families, and are usually found in individuals who are otherwise healthy. In children, that means they are growing well, have normal lab and x-ray results, and dont have "alarm symptoms" like blood in the stool, weight loss or fevers. The most common pediatric functional GI condition is functional abdominal pain. Children with this ...
Causes of Gastrointestinal manifestations of cystic fibrosis, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.
These findings do not support a distinct pathology unique to autism. Additionally, Wakefields original claim was essentially, MMR vaccination, then appearance of gastrointestinal symptoms, then regression into autism. So not only was Wakefields original claim roundly disproven, but Balzola et al.s findings do not indicate anything remotely descriptive of Wakefields original claim. This abstract also remains just that, i.e. an abstract presented at a meeting 5 years ago and has not gone through any peer-review, nor publication.. Finally, number 5, Galiatsatos et al., is a case report, featuring two adult patients with gastrointestinal problems and an ASD diagnosis. The authors call for "more investigations" in their discussion.. So what do we have here? Three (3) genuinely published cases of autistic adults who had consulted a doctor for gastrointestinal problems and were found to have gastrointestinal problems. One conference report from April 2005 that has not gone through peer review and ...
Rome Foundation Introduces New Clinical Tool for Diagnosis of Functional Gastrointestinal Disorders in The American Journal of Gastroenterology: Functional GI Disorders Are Common, Comprise about 40 percent of GI Diagnoses
BACKGROUND: Adults with Down syndrome (DS) are predisposed to syndromic and environmental gastrointestinal conditions. METHOD: In a hospital-based clinic for adults with DS, a chart audit was conducted to assess the range and frequency of gastrointestinal conditions. RESULTS: From January 2003 to March 2005, 57 patients attended the clinic, average age 37 years (range 17-63), 34(60%) male, and 12(21%) with a history of institutionalisation. Of these, 56 were found to have at least one gastrointestinal concern. Of the genotypic conditions, the prevalence was as follows: 6(12%) of 51 tested had likely celiac disease, 1(2%) had achalasia, 1(2%) inflammatory bowel disease, 1(2%) cholelithiasis, 2(4%) unexplained abnormal liver function tests, 1(2%) extrinsic oesophageal compression, and 5(9%) gastro-oesophageal reflux. Of the environmental conditions, 29(67%) of 43 tested had H. pylori infection; 13(25%) of 53 tested had hepatitis B infection (including 2 HbsAg positive, 0 HbeAg positive), 22(42%) ...
Treatment of psoriasis who have functional gastrointestinal disorder : Two Case Reports - functional gastrointestinal disorder;psoriasis;herbal medicine;skin disease;PASI;
Functional GI disorders are defined as Chronic abdominal symptoms without any structural abnormality. Common functional GI disorders are Functional Dyspepsia (FD), Irritable Bowel Syndrome (IBS), and Gastro-Oesophageal Reflux Disease (GERD). Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders. Irritable bowel syndrome (IBS), affecting approximately 10%-15% of the population based on Rome criteria as "abdominal pain or discomfort associated with altered bowel habits and disordered defecation". Gastroesophageal reflux disease (GERD) is characterized by the symptoms of heart burn and regurgitation caused by reflux of stomach content ...
Functional GI disorders are defined as Chronic abdominal symptoms without any structural abnormality. Common functional GI disorders are Functional Dyspepsia (FD), Irritable Bowel Syndrome (IBS), and Gastro-Oesophageal Reflux Disease (GERD). Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders. Irritable bowel syndrome (IBS), affecting approximately 10%-15% of the population based on Rome criteria as "abdominal pain or discomfort associated with altered bowel habits and disordered defecation". Gastroesophageal reflux disease (GERD) is characterized by the symptoms of heart burn and regurgitation caused by reflux of stomach content ...
Nausea, abdominal discomfort, and other gastrointestinal symptoms are commonly reported by individuals after drinking alcoholic beverages. The alcohol itself may cause gastrointestinal problems by affecting the gastric emptying process. Researchers at the University Hospital of Heidelberg at Mannheim in Germany conduced a systematic study of the effects of ethanol, alcoholic beverages, and the non-alcohol components of alcoholic beverages on the gastric emptying of solid meals in the human body, and the results suggest that alcohol rehab may improve gastrointestinal problems (Franke et. al., 2005).. The researchers recruited 16 fasting, healthy, male participants who received once weekly 300 ml of pure ethanol, beer, red wine, glucose, and water in a random order. The solutions were given with either a low-calorie or high-calorie solid meal. Real-time ultransonography was utilized to directly view the gastric emptying process. The researchers point out that ultrasonography is "simple, ...
Evidence showing the effectiveness of psychopharmacologic and psychotherapeutic management of functional gastrointestinal disorders over standard medical treatment is increasing. 1
Background:. Functional gastrointestinal disorder (FGID) is the most common gastrointestinal disease in daily clinical practice. The disease is symptomatic but has no identifiable cause by standard diagnostic tests such as endoscopy. It is characterized by its frequent relapses and thus the disease causes a significant level of stress and anxiety to patients. Due to the complexity and chronicity of the disease, it is believed that appropriate counseling on the nature and management of the disease is necessary to decrease patients anxiety level and improve quality of life.. Indication:. Patients who have symptoms suggestive of FGID including non-erosive gastroesophageal reflux disease (NERD), functional dyspepsia (FD) or irritable bowel syndrome (IBS).. Aim:. To validate the effectiveness of counseling in patients suffering from FGID.. Method:. Patients recruited to the study will follow the usual management of patients attending the Gastroenterology specialty clinic in Prince of Wales Hospital. ...
Pediatric functional gastrointestinal disorders are common but hard to diagnose and require multimodal treatment that may include compounded medications.
HIV itself can cause gastrointestinal disease. I have a patient who had a very similar experience. Eventually, her symptoms did resolve after the re-initiation of HIV therapy. Three weeks may not...
Gastrointestinal (GI) symptoms -- diarrhea, nausea, and stomach pain -- are among the most common problems that affect people with HIV. These symptoms can ...
Our busy modern lifestyles may be responsible for most cases of constipation. Insufficient fiber and water intake, not doing enough exercise, emotional and psychological problems can contribute to constipation. Persistent, chronic constipation may also be a symptom of health conditions including irritable bowel syndrome, colorectal cancer, diabetes, Parkinsons disease, multiple sclerosis, and depression. Some medications can also cause constipation which includes narcotic type painkiller and iron supplements.. Pilokare is an anti piles, anti-inflammatory, and antiprotozoal drug. It cures internal and external hemorrhoids, controls cramps, dyspepsia, flatulence, and nausea. It arrests bleeding from the bowel, wounds, and infections.. ...
The medication is an oral dose of human immunoglobulin, which contains antibodies to antigens that are thought to overstimulate the immune system and activate an autoimmune response. Some experts believe that the gastrointestinal problems and immune reactions may even be a cause or aggravator of autistic symptoms in some children.. "We are not sure why so many kids with autism tend to have these problems, but we do know that digestive problems add to the stress these children and their families already experience in dealing with the autistic disorder," said Dr. Michael Aman, principal investigator of the study at OSU and leader of the Research Unit on Pediatric Psychopharmacology in the College of Medicine and Public Healths Nisonger Center.. The study is designed to determine whether the medication improves gastrointestinal function and assess any related effects on emotions and behavior. In hopes that relieving the gastrointestinal problems might also help the autism, measures of autistic ...
The dietary plan is suggested to deal with gastrointestinal problems. Its less fiber content and like the majority of diets, united nations-tasty.. Brat weight loss program is a bland-food diet frequently suggested for adults and children struggling with gastrointestinal problems. Included in this are ailments like dyspepsia, diarrhea and gastroenteritis.. The brat is really a mnemonic for Blueberry, Grain, Applesauce and Toast - or foods which are united nations-flavorful and also have low fiber content. These food types can help an individual get over gastrointestinal upset. Extension of the diet includes tea, yogurt, steamed chicken and tapioca.. Other bland foods can be included to the diet plan such as the saltine crackers, steamed taters or obvious soups. Milk products, sugary and fats ought to be prevented soon after vomiting and diarrhea because they trigger a lot of latter, as well as nausea.. The dietary plan includes "binding" foods which are lower in fiber and may help to make ...
Research has uncovered some factors associated with the expression of IBS. Several of these established links include a major stressful life event, chronic stress, a reported history of physical, sexual, or emotional abuse, low birth weight, and environmental triggers such as infection with bacterial gastroenteritis. In some cases, IBS symptom intensity relates to the severity of the specific associated factor. To address some of these factors, and attempt to treat the associated IBS symptoms, a number of studies have examined various psychotherapy treatments, with mixed results.8 These approaches include relaxation training, dynamic psychotherapy, hypnotherapy, and combined psychotherapies. One thorough review published in 2003, showed psychological treatment may be effective for IBS, yet could not identify any one specific therapy to work any better than the others.9. Two recent notable studies with large sample sizes and rigorous methodology demonstrated encouraging results. The first ...
The first bowel movement of a newborn is called meconium. This is a sticky, greenish-black substance that forms in the intestines during fetal development. The baby may have several meconium bowel movements before this substance is completely gone from the babys system. After the first few days, normal bowel movements become yellow and formed in formula-fed babies. They may happen once or twice a day, sometimes more often. Breastfed babies tend to have soft, seedy, yellow-green bowel movements several times a day. They may be as often as every few hours with feedings. Babies with diarrhea have watery, very loose bowel movements that happen very often. A baby may or may not have signs of cramping with the diarrhea. Watery bowel movements and diarrhea in a newborn can quickly lead to severe dehydration. It should be treated right away. Talk with your babys healthcare provider if there is a change in your babys bowel movements or your baby develops diarrhea. If there is blood in the stool, call ...
Untreated acid reflux can cause serious health conditions. The general belief is that acid reflux is just an uncomfortable sensation that can be treated if it bothers the patient. But in reality untreated acid reflux can cause esophageal cancer, which is one of the most fatal cancers of gastrointestinal tract ...
However, during late childhood and early adolescence the "adult" features of myotonic dystrophy appear. Eye problems can be early on detected by the second decade and progressively muscles will be detected gradually weakening. No case of CMD has been found not to develop the adult version. OBrien reports that of 46 patients with CMD 4 died outside the neonatal period at 4, 18, 19 and 22 years. Four more were considered seriously disabled with a poor prognosis. Problems seen in this group of 30 were gastrointestinal Problems in 8 (Constipation and abdominal pain) Talipes in 5. None in the group had any children and males showed marked testicular tubular failure indicating significant reproductive problems. Thus, long-term prognosis from a medical viewpoint is not bright.. Reardon noted that because of gastrointestinal problems children with CMD will show a positive anal dilation test. This test is sometimes used to diagnosis sexual abuse. Parents with CMD should be aware of this information. ...
Apgar scoring. The Apgar score is one of the first checks of your new babys health. The Apgar score is assigned in the first few minutes after birth to help identify babies that have difficulty breathing or have a problem that needs further care. The baby is checked at one minute and five minutes after birth for heart and respiratory rates, muscle tone, reflexes, and color. Each area can have a score of zero, one, or two, with ten points as the maximum. A total score of ten means a baby is in the best possible condition. Nearly all babies score between eight and ten, with one or two points taken off for blue hands and feet because of immature circulation. If a baby has a difficult time during delivery, this can lower the oxygen levels in the blood, which can lower the Apgar score. Apgar scores of three or less often mean a baby needs immediate attention and care. However, only 1.4 percent of babies have Apgar scores less than seven at five minutes after birth.. ...
My Son Master ShivCharan aged 2 months was suffering from Stomach-ache and vomiting, where he was unable to express the pain in that teething age. Ultrasound and MRI scan were performed on my baby and diagnosed that he had a very severe problem-it is called Choledochal cyst, a by-birth problem where there is swelling of the bile duct (a tube that carries bile from the liver into the intestine ...
Answer 1 of 27: You have nothing to worry about regarding the Ritz Carlton food. It is the best of the best! I have visited the hotel many many times and never have had a problem. I a huge foodie and try everything. You can read numerous reviews here regarding...
Probiotics are common adjunctive therapy used in human and veterinary medicine, mostly intended for gastrointestinal diseases treatment or prevention. Lactic acid bacteria: Lactobacilli, bifid bacteria and enterococci and Saccharomyces boulardii, a subtype of the nonpathogenic yeast have been most frequently used as probiotic active ingredients. To become a recognized effective probiotic, a certain microorganism must fulfill many expectations, primarily the ability to survive gastrointestinal tract passage, adhere to epithelial cells and colonize intestines to present antimicrobial effect and inhibition of enteric pathogens. Prior to evaluation of clinical efficiency, it is advised to perform in vitro studies in order to identify potentially beneficial properties of probiotic organisms. An effective probiotic product could be of a great value in equine medicine, since both, adult horses and foals, frequently exhibit gastrointestinal problems. However, very little objective research has been carried out
Gastroenterology, Digestive and Gastrointestinal Conditions Conference scheduled on December 10-11, 2020 in December 2020 in Rome is for the researchers, scientists, scholars, engineers, academic, scientific and university practitioners to present research activities that might want to attend events, meetings, seminars, congresses, workshops, summit, and symposiums.
Autism spectrum disorders (ASDs) are a set of complex neurodevelopmental disorders defined behaviorally by impaired social interaction, delayed and disordered language, repetitive or stereotypic behavior, and a restricted range of interests. ASDs represent a significant public health issue with recent estimates indicating that as many as 1% of children in the United States are diagnosed with an ASD.1,2 Many individuals with ASDs have symptoms of associated medical conditions, including seizures, sleep problems, metabolic conditions, and gastrointestinal (GI) disorders, which have significant health, developmental, social, and educational impacts. Gastrointestinal complaints are a commonly reported concern for parents and may be related to problem behaviors and other medical issues such as dysregulated sleep (ATN Annual Registry Report, unpublished data, November 2009).3 Despite the magnitude of these issues, potential GI problems are not routinely considered in ASD evaluations. This likely ...
Precision Research Institute in San Diego offers a wide variety of clinical research trials for those Gastrointestinal Disease. Gastrointestinal disease refer to issues that occur throughout the GI tract, from the mouth all of the way down to the intestines. We offer studies in Ulcerative Colitis, Diabetic Gastroparesis, Colonoscopy, Irritable Bowel Syndrome, Hepatitis C, Constipation, Chronic Pancreatitis and Functional Dyspepsia. Here is a full list of our current Gastrointestinal Disease studies.. ...
This is a common condition in which patients suffer symptoms of upper gastric discomfort or pain in spite of normal endoscopy, ultrasound and other assessments. About one third of patients demonstrate delayed gastric emptying [49], another third demonstrate impaired gastric relaxation and about the same number demonstrate hypersensitivity to gastric distension [50, 51]. In general symptoms relate rather poorly to the abnormalities demonstrated, though Stanghellini et al.[49] found that severe vomiting and postprandial fullness together with female sex were predictive of delayed gastric emptying.. The demonstration of these abnormalities has encouraged the use of drugs to reverse them. In particular, initial interest focused on the role of cisapride, which had been shown to accelerate gastric emptying [52]. Cisapride also enhances postprandial gastric relaxation [53], whilst during fasting it increases fundal tone and perception of distension. These multiple actions may explain the somewhat ...
If your child meets the criteria for a functional gastrointestinal disorder, your physician may choose to do some tests to confirm the absence of disease, such as upper endoscopy for dyspepsia, or blood tests for celiac disease or inflammatory bowel disease.. Many children have bellyaches that do not meet the criteria for a functional gastrointestinal disorder, often because the symptoms are not as frequent, or have not been going on for as long as required for the symptom-based diagnosis.. Some children with functional abdominal pains get pale skin or blotchy skin, dizziness or faintness, or fatigue when they get a bellyache. These are signs of autonomic arousal, the chemical and hormone response of the body to the stress of a bellyache. Some children get headaches or body aches at the same time they get bellyaches.. If your child seems to have the symptoms that qualify as a functional gastrointestinal disorder, it is a good idea to learn more about these disorders by visiting your childs ...
Press Release issued Feb 22, 2017: Gastrointestinal system is made up of gastrointestinal tract and accessory organs. Gastrointestinal system is a long hollow tube that extends from your oral cavity where food enters the body, via the oesophagus, stomach, small intestine, large intestine, rectum, and finally to the anus where undigested food is expelled. The accessory organs include salivary glands, pancreas, gall bladder and liver. These organs help to secrete enzymes into the digestive tract. The main function of gastrointestinal tract is to process nutrients and energy from food and fluids that is ingested. Mobility and functional gastrointestinal disorders are most common gastrointestinal disorders in the population. Gastrointestinal mobility is the movement of the digestive system and the transit of the content within it. Esophageal disorders, gastro-duodenal disorders, bowel disorder and abdominal pain are some of the gastrointestinal diseases. These diseases are caused due to eating low fiber
Most patients will experience hepatobiliary manifestations at some point during the course of their HIV disease, with hepatomegaly and/or jaundice in 50% and abnormal liver function tests in over 80%. Despite their frequency, however, the approach to patients with such abnormalities remains problematic. Although most conditions found on liver biopsy represent systemic opportunistic infections or neoplasms, liver disease itself is rarely the cause of death.(157) Instead, the clinical and histologic expression of most diseases in the liver is attenuated because of the impaired immune response. In addition, most liver disorders that are diagnosed in patients with AIDS reflect advanced immunosuppression and occur late in the natural history of AIDS, when little can be done to improve overall outcome. HIV can involve the liver directly, as demonstrated by the presence of HIV p24 within Kupffer cells and hepatic endothelial cells(158) and HIV messenger RNA within hepatocytes.(159) Hepatic macrophages ...
Most patients will experience hepatobiliary manifestations at some point during the course of their HIV disease, with hepatomegaly and/or jaundice in 50% and abnormal liver function tests in over 80%. Despite their frequency, however, the approach to patients with such abnormalities remains problematic. Although most conditions found on liver biopsy represent systemic opportunistic infections or neoplasms, liver disease itself is rarely the cause of death.(157) Instead, the clinical and histologic expression of most diseases in the liver is attenuated because of the impaired immune response. In addition, most liver disorders that are diagnosed in patients with AIDS reflect advanced immunosuppression and occur late in the natural history of AIDS, when little can be done to improve overall outcome. HIV can involve the liver directly, as demonstrated by the presence of HIV p24 within Kupffer cells and hepatic endothelial cells(158) and HIV messenger RNA within hepatocytes.(159) Hepatic macrophages ...
Persons with diabetes mellitus often have disordered gastrointestinal function, usually attributed to autonomic neuropathy. Hypoglycemia in persons taking insulin has been considered a possible result of anorexia and gastric atony, but not a potential cause of gastrointestinal symptoms. Three patients with diabetes developing before age 30 yr and of long duration had severe gastrointestinal complaints for 1-9 mo, with symptoms suggesting nocturnal hypoglycemia. All recovered rapidly with no specific treatment other than reduction of insulin doses. Studies identified no gastrointestinal pathology. These patients may represent a subgroup of persons with diabetic enteropathy, in whom recurrent hypoglycemia provokes a reversible derangement of gut function with accompanying symptoms.. ...
Functional GI and motility disorders in children refer to a wide variety of digestive conditions that occur from birth to 18 years old.. A functional GI disorder refers to a condition where the primary abnormality is an alteration in the way the body works (altered function), rather than an identifiable structural or biochemical cause.. Gastrointestinal motility is defined by the movements of the digestive system, and the transit of the contents within it. When nerves or muscles in any portion of the digestive tract do not function normally, symptoms may result. While GI motility can be measured using tests, abnormal patterns do not always cause symptoms. When symptoms are present motility tests provide information to help with diagnosis and treatment.. ...
Autism Spectrum Disorders (ASD) are behaviorally defined by impairments in communication, social interactions, and repetitive stereotypic behaviors. Many children with ASD also experience gastrointestinal (GI) symptoms such as irregular bowel movements.
Bioactive Food as Dietary Interventions for Liver and Gastrointestinal Disease provides valuable insights for those seeking nutritional treatment options for those suffering from liver and/or related gastrointestinal disease including Crohns, allergies, and colitis among others. Information is presented on a variety of foods including herbs, fruits, soy and olive oil. This book serves as a valuable resource for researchers in nutrition, nephrology, and gastroenterology. * Addresses the most positive results from dietary interventions using bioactive foods to impact dis
This Fascicle is devoted to benign gastrointestinal diseases and provides an in-depth discussion of many lesions, both common and uncommon. This volume is, for the most part, organized by category of disease rather than by anatomic site. This approach allows for comprehensive coverage of each entity and avoids redundant descriptions of lesions that occur in multiple regions of the gastrointestinal tract. Each disease entity is discussed from the point of view of its demographics, pathophysiology, clinical features, gross and microscopic pathology, and treatment. The text is heavily illustrated with diagrams and gross and microscopic photographs. Because of the extreme importance of clinical and endoscopic correlation with interpretation of gastrointestinal pathologic specimens, an actively practicing gastroenterologist has been included among the authors. He has added endoscopic pictures and provides clinical insights critical to the understanding of gastrointestinal diseases ...
Food allergies, celiac disease, inflammatory bowel disease (IBD), diarrhea and other gastrointestinal diseases have something in common: all have been linked to epithelial barrier loss. The gut epithelial barrier-that critical lining of cells in the gut that must allow nutrients into the body while keeping food-borne microbes out-can be compromised during intestinal inflammation and cause disease. While many of the molecular mechanisms that trigger gastrointestinal diseases remain a mystery, previous research has found that one enzyme, known as myosin light chain kinase (MLCK), plays a critical role. However, MLCK is also essential for critical functions in gut epithelia and other cell types. This makes direct inhibition of MLCK impossible, as it would result in many toxic and systemic side effects. A team led by investigators from Brigham and Womens Hospital has now developed an alternative approach. In a study published in Nature Medicine, the researchers report new evidence suggesting that ...
Paediatric Gastroenterology-A Formidable Past, a Challenging Future the first chapter of this multiple, and international, author textbook highlights the recent impressive advances in our understanding of gastrointestinal diseases in children. The second edition could not have come at a better time, with many countries now recognising certification in this rapidly developing subspecialty. The two volumes are divided into six sections: I. Approach to child and family; II. Normal development and function; III. Cardinal manifestations: pathophysiology; IV. Clinical manifestations and management; V. Diagnosis of gastrointestinal disease in children; and VI. Principles of therapy.. In attempting to make the most of the new while retaining the best of the old, the first edition (published 1991) has been extensively reviewed. While highlighting important technological advances the editors have ensured that the lessons of the past have not been forgotten. The unique qualities of children and the ...
Twenty years ago the literature was full of varying definitions of functional gastrointestinal disorders, which was impeding research. A degree of homogeneity has been brought about by the Rome committee, who have regularly updated their definitions with the Rome II and now Rome III classifications of functional gastrointestinal disease. The Montreal group have attempted to bring a similar degree of consensus to the definition of gastro-oesophageal reflux and related diseases. The group consisted of experts from 18 countries, with the disciplines of gastroenterology, primary care and surgery represented. A rigorous Modified Delphi process was used to reach consensus and ,67% agreement was reached on all 51 statements. The definitions varied from the benign "GORD is a condition which develops when the reflux of stomach contents causes troublesome symptoms and/or complications" to the contentious "When biopsies of endoscopically suspected oesophageal metaplasia show columnar epithelium it should ...