Sentinel species such as the Atlantic killifish (Fundulus heteroclitus) living in urban waterways can be used as toxicological models to understand impacts of environmental metabolism disrupting compound (MDC) exposure on both wildlife and humans. Exposure to MDCs is associated with increased risk of metabolic syndrome, including impaired lipid and glucose homeostasis, adipogenesis, appetite control, and basal metabolism. MDCs are ubiquitous in the environment, including in aquatic environments. New Bedford Harbor (NBH), Massachusetts is polluted with polychlorinated biphenyls (PCBs), and, as we show for the first time, tin (Sn). PCBs and organotins are ligands for two receptor systems known to regulate lipid homeostasis, the aryl hydrocarbon receptor (AHR) and the peroxisome proliferator-activated receptors (PPARs), respectively. In the current study, we compared lipid homeostasis in laboratory-reared killifish from NBH (F2) and a reference location (Scorton Creek, Massachusetts; F1 and F2) to ...
TY - JOUR. T1 - Evolutionary Toxicogenomics of the Striped Killifish (Fundulus majalis) in the New Bedford Harbor (Massachusetts, USA). AU - Ruggeri, Paolo. AU - Du, Xiao. AU - Crawford, Douglas L. AU - Oleksiak, Marjorie F. PY - 2019/3/5. Y1 - 2019/3/5. N2 - In this paper, we used a Genotyping-by-Sequencing (GBS) approach to find and genotype more than 4000 genome-wide SNPs (Single Nucleotide Polymorphisms) from striped killifish exposed to a variety of polychlorinated biphenyls (PCBs) and other aromatic pollutants in New Bedford Harbor (NBH, Massachusetts, USA). The aims of this study were to identify the genetic consequences of exposure to aquatic pollutants and detect genes that may be under selection. Low genetic diversity (HE and π) was found in the site exposed to the highest pollution level, but the pattern of genetic diversity did not match the pollution levels. Extensive connectivity was detected among sampling sites, which suggests that balanced gene flow may explain the lack of ...
WASHINGTON - The Department of Justice, on behalf of the U.S. Environmental Protection Agency (EPA), along with the Massachusetts Attorney Generals Office, on behalf of the Massachusetts Department of Environmental Protection, have reached a settlement with AVX Corp. for $366.25 million plus interest regarding the New Bedford Harbor Superfund Site, in New Bedford, Mass. The settlement paves the way for expedited implementation of the cleanup of the New Bedford Harbor Site at full capacity, providing more rapid protection of public health and the environment in addressing polychlorinated biphenyl (PCB) contaminated sediment in the harbor. PCBs are mixtures of up to 209 individual synthetic chlorinated compounds that are chemically stable, attach onto sediment particles readily and are resistant to biodegradation. PCBs are characterized as a probable carcinogen in humans. The settlement follows an April 18, 2012, enforcement order issued by EPA to AVX to implement the ongoing cleanup work at the ...
EPA has issued an enforcement order to AVX Corp. to implement the ongoing cleanup work at New Bedford Harbor, including dredging PCB-contaminated sediment from the Harbor and disposing the dredged sediment to an appropriately licensed off-site facility, into a confined aquatic disposal cell in the Harbor, and into confined disposal facilities to be built along the shoreline.
Gulf killifish Fundulus grandis are a euryhaline baitfish species that could diversify aquaculture production in the southeastern US, however, little is known regarding low salinity or freshwater inland culture for any life history stage. Therefore, this research focused on physiological tolerance and performance in hypo-osmotic conditions during early life stages. In the first experiment, embryo and larval survival and two week larval length and weight were recorded for embryos air incubated in either 0ppt or 7ppt and hatched at the same or opposite salinity. Both the embryos and larvae survived and grew better in 7ppt conditions leading to the conclusion that the hypo-osmotic tolerance may improve with age or size. In the second experiment, killifish are currently being exposed to salinities of 0, 2.5, 5, and 7.5 ppt at 2, 7, and 12 weeks post-hatch in order to understand how hypo-osmotic tolerance changes with development. It is hypothesized that killifish gain hypo-osmotic tolerance with age ...
This is an unofficial version of Commonwealth regulations and is posted here for the convenience of the public. It is not an official statement of the regulations.
NEW BEDFORD - A traffic stop prompted by a state troopers suspicions over the legality of a cars window tint in New Bedford Friday led to the arrest of a man for trafficking in fentanyl, among other charges, according to Massachusetts State Police. According to a press release, at about 5:20 p.m., troopers assigned to the Troop D Community Action Team stopped a 2019 Nissan Altima for suspected illegal window tint. During their contact with the operator, the troopers observed a knife in
NEW BEDFORD - Grammy award-nominated jazz musician Armsted Christian, a Berklee School of Music professor who performed with entertainers including Diana Ross, Patti Austin and Regina Carter, lost his long battle with sarcoidosis Monday at 64.Although his career took him across the globe, the Poughkeepsie, New York native spent more than two decades of his life in New Bedford and embraced his adopted city, where he frequently performed.
The extrinsic eye muscles of the killifish (F. heteroclitus) were fixed in OSO4 (pH 7.6) and subsequently dehydrated, embedded, and sectioned for electron microscopy. The fine structures of neuromuscular junctions and of sarcoplasmic reticulum were then observed.. The neuromuscular junction consists of the apposition of axolemma (60 to 70 Å) and sarcolemma (90 to 100 Å), with an intervening cleft space of 200 to 300 Å, forming a synaptolemma 400 to 500 Å thick. The terminal axons contain synaptic vesicles, mitochondria, and agranular reticulum. The subsynaptic sarcolemma lacks the infolding arrangement characteristic of neuromuscular junctions from other vertebrate skeletal muscle, making them more nearly like that of insect neuromuscular junctions. A comparison between the folded and non-folded subsynaptic membrane types is made and discussed in terms of comparative rates of acetylcholine diffusion from the synaptic cleft and resistances of the clefts and subsynaptic membranes. The ...
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The Regeneration Project began in March of 2014 when Mayor Mitchell asked many of the regions business and community leaders to serve as members of the New Bedford Regeneration Committee. The task before the committee was to articulate a strategy for the Citys economic regeneration that builds on the committees collective experience in leading successful enterprises. The committees final report is a statement that was intended to attract broad popular buy-in, shape the economic development strategy over a five-year period, and signal to both private investors and government officials outside the region that New Bedford has a clear set of objectives.. Gerry Kavanaugh served as chairman and the NBEDC staffed the committees work. The Boston-based non-partisan think-tank MassINC and the UMass Dartmouth Urban Initiative, together facilitated the committees work and drafted their report-Uniting in Pursuit of Growth and Opportunity, which was presented to Mayor Mitchell in November of ...
context source (Introduced species) Katsanevakis, S.; Bogucarskis, K.; Gatto, F.; Vandekerkhove, J.; Deriu, I.; Cardoso A.S. (2012). Building the European Alien Species Information Network (EASIN): a novel approach for the exploration of distributed alien species data. BioInvasions Records. 1: 235-245., available online at http://easin.jrc.ec.europa.eu [details] ...
Hemic neoplasia, a leukemia-like disease, is a fatal cancer subtype in soft-shelled clams with varying prevalence and fatality rates along the Atlantic coast of North America. The highest incidence is near New Bedford Harbor, MA, an EPA superfund site with high levels of carcinogens in the sediment and water column. Recently, Metzger et al. (Cell, 2015) discovered that hemic neoplasia is not caused by viral infection as previously thought, but by cancer cells traveling from clam to clam. This was evidenced by identical clonal genotypes found in clams separated by hundreds of miles. These cancer cells were also shown to have unique genotypes compared to the matched non-cancer tissue, suggesting a single origin of the cancer cells rather than novel somatic mutations.. Hemic neoplasias are not unique to soft-shelled clams, but occur in many other bivalve species including mussels, cockles and oysters. However, transmission methods in these species have not yet been investigated. Given that ...
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Bedfords attempts to control the mosquito population will continue Thursday as Bedford will receive another spray of insecticide with the aim of reducing the adult mosquito population in the area. The spraying will take place on Thursday, June 15 between dusk and 11 p.m. according to a notice posted on the towns website.Spraying is scheduled in neighborhoods in the vicinity of Concord Road, Davis Road, Carlisle Road, and North Road. The aim is cut down on the mosquito population that is
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Tonights AHA! presents an evening of cultural walking tours and talks in downtown New Bedford. Additional attractions include art exhibits, live music, shopping and dining. AHA! welcomes new partners The Bedford Merchant (28 William St.) and the Colo Colo Gallery (25 Centre St.).Complete schedules are available at all listed partners or online at www.ahanewbedford.org. Activities are free, and held rain or shine, and run from 5 to 9 p.m. HighlightsThe Old Bedford Village Community Development Corporation presents a walking tour of Old Bedford Village led by Buddy Andrade. Tour starts at the corner of South Sixth Street and Spring Street at 5 p.m.Learn about the commercial fishing industry on a guided dock walk sponsored by the Working Waterfront Festival. Tours depart from the Wharfinger Building (State Pier) at 5:30 and 7 p.m.WHALE (Waterfront Historic Area LeaguE) presents a Preservation Walking Tour of New Bedford Whaling National Historical Park and State Pier. Tour leaves fr ...
Abstract Background While studies of non-model organisms are critical for many research areas, such as evolution, development, and environmental biology, they present particular challenges for both experimental and computational genomic level research. Resources such as mass-produced microarrays and the computational tools linking these data to functional annotation at the system and pathway level are rarely available for non-model species. This type of "systems-level" analysis is critical to the understanding of patterns of gene expression that underlie biological processes. Results We describe a bioinformatics pipeline known as FunnyBase that has been used to store, annotate, and analyze 40,363 expressed sequence tags (ESTs) from the heart and liver of the fish, Fundulus heteroclitus. Primary annotations based on sequence similarity are linked to networks of systematic annotation in Gene Ontology (GO) and the Kyoto Encyclopedia of Genes and Genomes (KEGG) and can be queried and computationally ...
TOXMAP helps users create nationwide or local area maps showing where TRI chemicals are released on-site into the air, water, and ground. It also identifies the releasing facilities, color-codes release amounts for a single year, and provides multi-year chemical release trends, starting with 1987. Maps can also show locations of Superfund sites on the National Priority List (NPL) (http://www.epa.gov/superfund/sites/npl), listing all chemical contaminants present at these sites. Users can search the system by chemical name, chemical name fragment, and/or location (such as city, state, or ZIP code). TOXMAP also overlays map data such as US Census population information, income figures from the Bureau of Economic Analysis, and health data from the National Cancer Institute (http://www.cancer.gov/) and the National Center for Health Statistics (http://www.cdc.gov/nchs ...
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Many U.S. veterans of the Afghanistan and Iraq wars aren't getting needed mental health treatment for conditions such as post-traumatic stress disorder, depression or substance abuse, a...
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A listing of facilities available for use can be viewed here. Depending on the type event you wish to hold, the application process may require review and approval of the Bedford School Board and/or the Bedford Police and Fire Departments. For more information on when these approvals are required, please refer to the Health & Safety section below. A certificate of insurance must be on file at the SAU Office prior to any facility use approval. ...
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MOUNT KISCO, N.Y. -- The physicians of Bedford Anesthesia, PLLC have joined CareMount Medical as of Jan. 1.Formerly Mount Kisco Medical Group (MKMG), the practice changed its name to CareMount nearly a year ago, though MKMG is still wide...
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