Frasier syndrome is a rare inherited disease characterized by steroid-resistant nephrotic syndrome, gonadal tumor, and male pseudohermaphroditism (female external genitalia with sex chromosomes XY), which is based on a splice site mutation of Wilms tumor-suppressor gene 1 (WT1). Several unusual Frasier syndrome cases have been reported in which male pseudohermaphroditism was absent. We reviewed 88 Frasier syndrome cases in the literature and classified them into three types (type 1-3) according to external genitalia and sex chromosomes, and described their clinical phenotypes. Type 1 Frasier syndrome is characterized by female external genitalia with 46,XY (n = 72); type 2 by male external genitalia with 46,XY (n = 8); and type 3 by female external genitalia with 46,XX (n = 8). Clinical course differs markedly among the types. Although type 1 is noticed at the mean age of 16 due to mainly primary amenorrhea, type 2 and 3 do not present delayed secondary sex characteristics, making diagnosis ...
The Frasier theme song is entitled "Tossed Salad and Scrambled Eggs." It became part of a Frasier Soundtrack CD released in 2001 (by Lifetime Television) entitled "Frasier: Tossed Salad & Scrambled Eggs," but the main title track is different from the one played at the start of the show. The CD version featured Kelsey Grammer uttering the words with various back-up artists singing like a chorus in the background.. As of now I do not know who are the credited writers of the song but it definitely was made for the show.. Additional. People actually analyzed what "Tossed Salads and Scrambled Eggs" meant. ...
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Did you see Dr. KElly Frasier of Kleiman Evangelista Eye Centers at the American Airlines Center in Dallas when he was inside The Octagon for UFC 185? The ophthalmologist keeps a watchful eye on the fighters as one of the on-site doctors.
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‎In the third season of Frasier additions to the recurring cast include Irene Olga Lopez as Marta, Maris maid and go-between, Luke Tarsitano as Frasiers son, Frederick and Kate Costas (Mercedes Ruehl), the headstrong, ratings-obsessed new manager of Frasiers home radio station KACL, with wh…
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in animal organ development. Predicted to localize to the nucleus. Human ortholog(s) of this gene implicated in several diseases, including Denys-Drash syndrome; Frasier syndrome; malignant mesothelioma; nephroblastoma; and nephrotic syndrome type 4. Is expressed in several structures, including cardiovascular system; gonad primordium; mesoderm; pleuroperitoneal region; and podocyte. Orthologous to human WT1 (WT1 transcription factor ...
The direct involvment of the Wilms tumor suppressor gene (WTl) in Denys-Drash syndrome through mutations within exons 8 or 9 has recently been established. The absence of such alterations in three patients with Frasier syndrome provides a molecular basis for distinguishing these two syndromes that are associated with streak gonads, pseudohermaphroditism and renal failure ...
Martin: Youre right, they do. Take me for instance. The old Martin would have said, "Youre oud of your mind. Id rather see you go gay and shack up with the punk who shot me than go off with her. Id rather see you sewed inside the body of a dead horse. But the new Martin says Viva lamour ...
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Can you pick the lines that follow the given lines from the tenth season of Frasier? Test your knowledge on this television quiz to see how you do and compare your score to others. Quiz by TheCleverone
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Oh man, what a totally productive way to distract yourself! Congrats on that. I would love to make a suggestion for your most recent post, but the only literary couple I can think of right now are Ron Weasley and Hermione Granger...probably not a big help to you. Im going to hop on over to your blog right now and read that first post though!. Delete ...
Chen-Plotkin, A. S., Albin, R., Alcalay, R., Babcock, D., Bajaj, V., Bowman, D., Buko, A., Cedarbaum, J., Chelsky, D., Cookson, M. R., Dawson, T. M., Dewey, R., Foroud, T., Frasier, M., German, D., Gwinn, K., Huang, X., Kopil, C., Kremer, T., Lasch, S. & 20 others, Marek, K., Marto, J. A., Merchant, K., Mollenhauer, B., Naito, A., Potashkin, J., Reimer, A., Rosenthal, L. S., Saunders-Pullman, R., Scherzer, C. R., Sherer, T., Singleton, A., Sutherland, M., Thiele, I., Van Der Brug, M., Keuren-Jensen, K. V., Vaillancourt, D., Walt, D., West, A. & Zhang, J., Aug 15 2018, In : Science Translational Medicine. 10, 454, eaam6003.. Research output: Contribution to journal › Review article ...
Ms. Ziemba, like Ms. Monk, is an appealing and polished veteran who never makes a technical misstep. But the original, star-defining wit that both actresses have shown on previous occasions never manifests itself here.. Edward Hibbert, a specialist in droll poseurs with affected accents, does his usual shtick with his usual panache. And Jill Paice, as the classically winsome ingénue who captures Cioffis heart, subtly and deliciously sends up classical winsomeness.. She is well paired with Mr. Hyde Pierce, who fans the audience-wooing spark he demonstrated as the most cowardly of the knights in "Spamalot" into a steady flame. As the theater-smitten Cioffi, who winds up solving the shows artistic problems as well as the murders, this elegantly understated comic makes captivating use of a Boston accent, a diffident air and the instinctive, razor-edge timing he honed on the sitcom "Frasier.". Hes a welcome oddity, a soft-sell star in a hard-sell world. He uses this incongruity to make Cioffi a ...
Obviously The Simpsons is dying from being squeeze out with pop culture references irrelevant to the plot, expensive popular music licenses and guest stars that for the most part has little to do with the episode. One of the worst was the unfunny totally irrelevant halloween episode where Homer and Marge became cast in an assortment of famous "male-female" stories. It only takes one or two of those to get the Simpson fans to say "OMG THAT WAS FUNNY EPISODE BECAUSE I NOE THAT MOVIE TOO." Even more WTF is the increasingly unbearable militant Lisa, trying too hard to be sexy Marge, and stupid aphnetworks.com one dimensional Homer -- no thanks, Id rather watch mid-seasons Family Guy, and Id prefer watch South Park season 2-3 over that, and by then I would resort to watching Frasier episodes which I watched 2 weeks ago for the 4th time ...
Written by Martha Stout, Narrated by Shelly Frasier. Download the app and start listening to The Sociopath Next Door today - Free with a 30 day Trial! Keep your audiobook forever, even if you cancel. Dont love a book? Swap it for free, anytime.
Azadniv M; Torres A; Boscia J; Speers DM; Frasier LM; Utell MJ; Frampton MW; Inhalation Toxicology, 2001, vol. 13, issue 6, p 485, ISSN 08958378. ISBN 08958378. ...
Author Bio:. Elaine Stock never expected that a college major in psychology and sociology would walk her through the see-saw industries of food service and the weight-loss business; co-ownership with her husband in piano restoration; and ten years in community leadership. All great fodder for creating fiction.. In the spring of 2011 Elaine placed in the Semi-finals category in the ACFW Genesis Contest for her novel WALK WITH ME. In 2013 she received the honor of My Book Therapys Frasier Bronze Medalist award for NO GOING BACK. And in 2014 she was blessed with the news that her short story IN HIS OWN TIME won the Peoples Choice Award in the FamilyFiction Contest and will be published in a printed anthology. Her short story, THE FOREVER CHRISTMAS GIFT is about to be released in CHRISTMAS TREASURES: A COLLECITON OF SHORT STORIES.. Elaines blog, Everyones Story has been graced by an awesome international viewership. She hosts weekly interviews and reflections from published authors, unpublished ...
Establishing hand-eye coordination and exceptional attention to detail is another challenge facing the IPP students. When you are first learning how to perform a task it is best to take your time and have a successful outcome, instead of rushing and producing a sloppy product. Here in IPP, the products must be done quickly with precision, and be beautiful when completed. They must all look exactly the same. Each team is responsible for supplying pastries for an in-class buffet that we set-up on the marble table with white linens and plexi-glass risers. When they look at their products lined up, it is easy to identify any issues they had with production and uniformity from one pastry to another. In IPP it is stressed that all products are the same in order to deliver the same quality to every guest. For instance, if you are selling a slice of Frasier in your bakery for $5.00, and one is half the size of the other, you cannot expect the guest to pay the same price for a smaller product, which ...
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This oddly shaped EKG, patterned from the logo of the Frasier television show, was designed by a gal named Dixie Allan at about.com. Dixies bio describes her as a freelance graphic designer and art professor with 35 years of experience, and she looks like the nicest lady you would ever meet, so Im not going to make fun of her here in this blog ...
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Indian Head at Frasier Island. I met a nice Irish girl on the tour and she was headed north as well. We jumped in the car that evening, planning to drive through the night to get to Airlie Beach early enough to make the first departures for the Whitsunday islands. I ended up using a loaf of bread as a pillow to try and sleep while she drove and ended up tearing the bag as I rolled around and sent bread flying all over the backseat. From Airlie I went out on a 3 day sailboat diving excursion to the Whitsunday Islands. It was one of the most beautiful places Ive ever been to. Im going to go back and take Lauren some day, especially after she saw some of the pictures of the beaches. The boat had about 25 people with 12 countries represented. All but 3 were under 30 years old. The diving was phenomenal. Bright coral, stingrays, fish twice the size of me were just part of it. My favorites were two Brazilian guys and two Norwegian girls. Both were hysterical. The girls taught me a little Norwegian. ...
The Paley Center for Media An accomplished television director and industry veteran, Pamela Fryman has wielded her magic wand over a couple of sitcoms you may have heard of: Friends, Suddenly Susan, The King of Queens and Frasier, just to name a few. Shes currently the in-house director on How I Met Your Mother, and after seeing her in action on set last season-a total pro and so well respected by cast and crew-I just had to have her for our TV Summer School feature. So, without further ado, class, lets get our learnin on... Im in awe of your résumé. Can you tell us how someone ends up being a successful television director? What was your first job in the business? Well, as a kid, I was sure that I loved to watch TV, so I got an internship when I was in high school. This will now really date me, but in 1977, I worked on The Mike Douglas Show, a talk show in Philadelphia. I grew up right outside of Philly and got to know some people … [Read more...] about TV Summer School: How to Become a ...
Sitcom star Kelsey Grammer, who suffered a recent heart attack, remains in a New York hospital after checking himself in early yesterday for feeling faint, reports Reuters. The Frasier actor was out... Celebrity News Summaries. | Newser
Except the Bible itself was written by people who were using the same moral system that Frasier complains about when talking about atheists. They did not get their morality from God. They got their morality by appealing to their own moral intuitions and desires - fully under the influence of their human capacity to deceive themselves into thinking they were doing the right thing, when they were simply doing what they wanted or what made them happy.. We can see evidence of the fact that the Bible was written by humans assigning their own beliefs and prejudices to God by the moral code that was written in the Bible. Naturally, church leaders would want everybody to owe them allegiance and to give allegiance to no other religion, so they began with, "Thou shalt have no other God before me." They approved of slavery, as long as they were not the ones being enslaved, so they approved a Bible that allowed the enslavement of people from other countries, but not the enslavement of their own ...
APRS is a registered trademark Bob Bruninga, WB4APR Copyright © 2003 - Glenn Frasier, KD5DMG All Rights Reserved 3 APRSWXNET/CWOP: a Beneficial Partnership of NOAA, Amateur Radio, and other Good Citizens Russ Chadwick KBØTVJ NOAA Forecast Systems Laboratory Boulder, Colorado September 13, 2002
Increasing evidence supports a genetic predisposition to the development of germ cell tumours. Genetic syndromes and multiple sex-chromosome aneuploidy syndromes leading to various degrees of gonadal dysgenesis have been consistently associated with germ cell tumour development, particularly but not limited to gonadoblastoma.. WT1-related disorders, most commonly Frasier syndrome and Denys-Drash syndrome (DDS), are described in association with ovarian gonadoblastoma. Both diseases are associated with steroid-resistant progressive nephropathy, gonadal tumours and male pseudohermaphrodism and therefore may easily be missed when the patient is phenotypically female.56 The WT1 gene is a tumour suppressor gene that encodes a zinc finger transcription factor involved in regulation of early gonadal and kidney development.57 58 It consists of 10 exons, with two regions of alternative splicing in exons 5 and 9. The final nucleotide of exon 9 codes for lysine, threonine and serine (KTS) and a correct ...
MalaCards based summary : Gonadoblastoma is related to ovarian gonadoblastoma and testicular gonadoblastoma, and has symptoms including hirsutism, ambiguous genitalia and abdominal pain. An important gene associated with Gonadoblastoma is TSPY1 (Testis Specific Protein, Y-Linked 1), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and Deactivation of the beta-catenin transactivating complex. Affiliated tissues include ovary, testis and prostate, and related phenotypes are no phenotypic analysis and reproductive system ...
from Alter Net. One of the ways reformers are trying to reduce the use of excessive police force is by requiring police officers to wear body cameras. Cities like Cleveland are moving toward requiring more officers to wear cameras to ensure accountability.. But a case out of Denver shows that not all police are so keen to be recorded. This past August, a group of police officers attempted to arrest David Nelson Flores for suspected drug possession. When he stuffed a sock in his mouth and refused to open his mouth, one of the officers struck him in the head repeatedly. "Those were the hardest punches I have ever heard, said Levi Frasier, a bystander who witnessed the beating.. But police did not limit their use of force to Flores. They also tripped his girlfriend, who was almost eight months pregnant at the time. Luckily for Flores and his girlfriend, Frasier…. ...
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Or maybe the scars are healing up.... Maybe. The lower 9th is filled with cicatrices, keloid scars covered in scrub, the lots cleared. Concrete steps still stand, but they no longer lead to a porch. Abandoned boarded up hovels still bear the government marks. The neighbourhood really opened up when the waves came in. Its so airy... So many lives gone. The stories moved away; the family photo albums, the kitchen table, the threadbare sofa; they went to another state, or they never went away, or they didnt... The spray can diagonal slashes would be so much more poignant if we could understand what them, we simple tourists ogling the catastrophe, snapping the heartbreak, feasting the recovery. Hammer blows are echoing around, exposed frames becoming slowly clad, pipes and wires and a roof and windows- a house and a rebirth.... and a home one day. Its a 10 year pregnancy barely in its second trimester ...
In 1953, Scully first described a unique gonadal neoplasm that strongly resembled a normally developing gonad and subsequently named the neoplasm gonadoblastoma. Gonadoblastoma is a rare benign tumor that has the potential for malignant transformation and affects a subset of patients with an intersex disorder or disorder of sex development (D...
David Lloyd, who not only wrote some of the greatest single episodes in TV sitcom history [Chuckles the Clown youtube], but consistently wrote hilariously, has died at 75. I especially loved a lot of his work on Frasier. With the death of Larry Gelbart (best known for M*A*S*H, but also a writer for the original Sid Caesar show, and of the movie Tootsie), a generation is passing. Itll be time soon for someone to do a retrospective on The Funniest Generation that assesses the effect of its sitcoms on our culture. And you can remind us all you want of how awful most sitcoms were and are, but there has almost always been at least one really funny sitcom running throughout American TVs history. Usually on a Thursday night on NBC, by the way.. Categories: entertainment dw ...
In 11 seasons of Frasier, John Mahoney played Marty Crane, a cussed blue-collar ex-cop who couldnt quite understand how his loins came to produce two prissily cultured psychiatrists. His ally in straight-talking was his physiotherapist Daphne, whose fish-out-of-water flat-cap vowels were apparently the result of a gap in the scriptwriters field of knowledge.. Read more... ...
One note that Ive actually managed to keep up with is one titled "Awesome Cat Names." I probably started it whenever I was looking for a name for my current cat, but like some kind of strange compulsion, Ive continued to add to it over time (by the way, the aforementioned cat is now named Frasier because, well, Im really gifted at picking names for cats). Im not even sure why I continue to curate this list since Im not in the market for a new animal friend. Regardless, itd be a shame to let this gem go to waste, so I thought I would share it here. If youve got a nameless feline, here are some timeless, bad ass things to call him/her ...
Penny, R., Olambiwonnu, N. O., and Frasier, S. D.: Follicle stimulating hormone (FSH) and luteinizing hormone-human chorionic gonadotropin (LH-HCG) concentrations in paired maternal and cord sera. Pediatrics, 53:41, 1974.. An error was made by the authors under the Materials and Methods section of the above article which appeared in the January issue. The last two sentences should read:. To convert to nanograms of LER 907, multiply FSH concentrations by 24 and LH concentrations by 17. For conversion to International Units of commercial HCG, divide LH-HCG concentrations by 0.55.. ...
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But no matter. It is December now, and because we travel for the holidays, it forces us to get our Christmas on early. The tree is up, a Frasier Fir packed tightly with funky ornaments, probably 1/4 penguins. While we were decorating, the Nugget repeatedly stated, "Christmas trees are the best! Christmas trees are the best, Mama! Daddy, Christmas trees are the best!" He helped us hang ornaments, preferring to create little "meetings", 4 penguins to a branch, a manatee kissing a giraffe, etc. We had to move a couple of his creations due to the laws of physics, but otherwise are content to leave his meetings be. Our family trees are not about perfection but about love and memories, and its always been that way, back to the day when my parents proudly hung up aluminum pie plates with magazine clippings glued inside, pipe cleaner candy canes, and salt dough ornaments scrawled with marker. I used to look at our random tree with concern, comparing it to the stark glittery beauties in dentist offices ...
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Disabled Army veteran Susan Frasier rides an overnight Greyhound bus alone each month to Washington, D.C., to walk the halls of Congress in search of elected officials who will support her where the U.S. Department of Veterans Affairs and federal courts have not. Despite her health problems and living on a fixed income, the Albany woman has for eight years traveled to the nations capital to press lawmakers to examine the health records of Fort McClellan veterans. Frasier counsels others who served at Fort McClellan, some of whom have also experienced health problems that are similar to those caused by Agent Orange exposure and Gulf War Syndrome. Like most female recruits and military police near the height of the Vietnam War, the Army assigned her to train at Fort McClellan in Anniston, Ala. What Frasier and tens of thousands of vets who passed through the base didnt know -- and many still dont -- was that the Armys experiments with chemical munitions on the base turned Fort McClellan into a
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Tsai and Frasier explain that the two UMass Amherst Doppler radars send different signals into a storm, reflecting off water droplets or debris and returning data at either a fine or more coarse resolution. For example, the high-frequency 95 GHz W-band radar provides "the highest spatial resolution of all existing mobile Doppler radars," Frasier notes. It can be very narrowly focused "because tornadoes are relatively small targets." Also, W-band radar can better image internal tornado structures. For best results, mobile W-band radar should be deployed quite close to a storm but not directly in its path, a mile or two to the side. Inside the truck, the engineer uses the radar to measure wind speed, density of raindrops, wind shear and other variables, Tsai adds. Frasier says this radar is critical to VORTEX2 because "it provides the best possible opportunity to map the wind field at the lowest levels of tornadoes. It also has the best chance to document the structure of multiple, ...
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