Global Fluorocarbon Rubber Sheets Market 2017, presents a professional and in-depth study on the current state of the Fluorocarbon Rubber Sheets market globally, providing basic overview of Fluorocarbon Rubber Sheets market including Definitions, Classifications, Applications and Industry chain structure, Fluorocarbon Rubber Sheets Market report provides development policies and plans are discussed as well as manufacturing processes and cost structures. Fluorocarbon Rubber Sheets market size, share and end users are analyzed as well as segment markets by types, applications and companies.. Download Free Sample Report @ http://www.fiormarkets.com/report-detail/34409/request-sample. Global market research report of Fluorocarbon Rubber Sheets 2017 mainly focuses on Production, means the output of Fluorocarbon Rubber Sheets and Revenue, means the sales value of Fluorocarbon Rubber Sheets in market. Fluorocarbon Rubber Sheets market research report studies Fluorocarbon Rubber Sheets in Global market, ...
Biocompatible fluorocarbon emulsions having fluorocarbon in concentrations of from 75% weight per volume to 125% weight per volume have small, biocompatible particle size stability through heat sterilization with one emulsifying agent, including phospholipids, in concentrations of from 3% to 7% weight per volume. The single emulsifying agent can be hydrogenated lecithins and synthesized lecithins. Fluorocarbon emulsions having fluorocarbon in concentrations of from 40% weight per volume to 125% weight per volume have stability of partial pressure of oxygen and of partial pressure of carbon dioxide through heat sterilization and storage for extended periods of time after having been oxygenated with dissolved oxygen. A method of preparing biocompatible fluorocarbon emulsions includes preparing a mixture of an emulsifying agent, osmotic agent, buffering agent, aqueous phase and fluorocarbon, forcing the mixture under high pressure into a cavity, against a surface and around a lip to cause turbulence and
Fluorocarbons, sometimes referred to as perfluorocarbons or PFCs, are, strictly speaking, organofluorine compounds with the formula CxFy, i.e. they contain only carbon and fluorine, though the terminology is not strictly followed. Compounds with the prefix perfluoro- are hydrocarbons, including those with heteroatoms, wherein all C-H bonds have been replaced by C-F bonds. Fluorocarbons can be perfluoroalkanes, fluoroalkenes and fluoroalkynes and perfluoroaromatic compounds. Fluorocarbons and their derivatives are used as fluoropolymers, refrigerants, solvents, and anesthetics. Perfluorocarbons or PFCs are, strictly speaking, organofluorine compounds with the formula CxFy, i.e. they contain only carbon and fluorine, though the terminology is not strictly followed. Compounds with the prefix perfluoro- are hydrocarbons, including those with heteroatoms, wherein all C-H bonds have been replaced by C-F bonds. Fluorocarbons can be divided into perfluoroalkanes, fluoroalkenes and fluoroalkynes or ...
Vascular endothelial growth factor is known to bind serum proteins (8) and we postulated that one of the binding proteins is albumin. It has previously been demonstrated that the ability of albumin to bind oligonucleotides remains intact in PESDA (20). The basic hypothesis of the study was that by destroying microbubbles containing VEGF in the coronary circulation, a large amount of VEGF would be released into the coronaries and taken up by the heart. However, this hypothesis failed to explain the phenomenon of significant increase in VEGF uptake with US alone that we observed. Perfluorocarbon-exposed sonicated dextrose albumin had minimal incremental effect on enhancing VEGF uptake. Most of the effect appears to be due to US energy, which may be locally enhanced by the presence of acoustically active microbubbles. Ultrasound-mediated enhancement of transfection has been reported in the literature (21-24) and is attributed to ultrasonic cavitation of cells. Since the transfected cells went on ...
This study was designed to assess the effects of blood-free reperfusion with oxygenated or unoxygenated intracoronary perfluorochemical (Fluosol-DA 20%) on myocardial perfusion and to determine its mechanism or mechanisms of limiting no reflow. Twenty-four dogs underwent 90 min of coronary occlusion followed by 210 min of reperfusion and were randomized to either: 1) blood-free reperfusion with intracoronary oxygenated perfluorochemical (20 ml/kg per min) for 20 min followed by blood reperfusion (n = 8); 2) intracoronary unoxygenated perfluorochemical administered as in those treated with oxygenated perfluorochemical (n = 8); and 3) blood reperfusion alone (control) (n = 8). Regional myocardial blood flow was serially determined and global myocardial perfusion was assessed by an intravenous injection of the fluorescent dye (thioflavin-S). Quantitative studies were performed to determine neutrophil infiltration and extent of endothelial injury.. Hemodynamic variables were similar in all groups. ...
Dietary intake has been estimated to be the major ongoing pathway of human exposure to perfluoroalkyl carboxylic acids (PFCAs) and perfluoroalkane sulfonic acids (PFSAs). However, difficulties associated with the analysis of food samples have hampered the reliable quantification of dietary exposure. Here the dietary exposure of the average Swedish population to PFCAs and PFSAs is estimated through analysis of a range of homologues in representative food basket samples from 1999, 2005 and 2010. Exposure to perfluorooctane sulfonate (796−1424 pg kg. -1day-1), perfluoroundecanoic acid (88−212 pg kg-1day-1), perfluorodecanoic acid (52−102 pg kg-1day-1) and perfluorononanoic acid (62−83 pg kg-1day-1) was dominated by the consumption of fish and meat. In contrast, exposure to perfluorooctanoic acid (322−513 pg kg-1day-1) originated from low levels (8−62 pg g-1) found in several ―high consumption‖ food categories including cereals, dairy products, vegetables and fruit. The average body ...
For PLV, perfluorodecalin (Fluka, Buchs, Switzerland), prewarmed to 38°C, was instilled to the rabbit lung through the endotracheal tube. Three doses of perfluorocarbon were tested: 9 ml/kg (defined as low dose) = 50% of the FRC dose, 13.5 ml/kg (defined as medium dose) = 75% of the FRC dose, and 18 ml/kg = FRC dose (chosen from the authors experience). At the application of the FRC dose, the perfluorocarbon column was visible through the endotracheal tube at end expiration. Six rabbits were randomly subjected to one of six different sequences of perfluorocarbon dosing: low-medium-FRC dose, low-FRC-medium dose, medium-low-FRC dose, medium-FRC-low dose, FRC-low-medium dose, FRC-medium-low dose. Change from a higher dose to a lower dose was accomplished by removing perfluorocarbon via the endotracheal tube corresponding to the difference between doses. In case the airway pressure showed an early pressure surge exceeding the end-inspiratory peak pressure, PEEP was transiently increased to push ...
EWGs Tap Water Database Perfluorononanoic acid (PFNA) results for City of Cape Coral | Perfluorononanoic acid (PFNA). Find out what is in your tap water
Dodecafluoropentane Emulsion (DDFPe) Decreases Stroke Size and Improves Neurological Scores in a Permanent Occlusion Rat Stroke Model
A dynamic seal assembly for installation between first and second relatively rotating members, comprising a ring for fixed engagement with said first member and an annular seal extending radially from said ring and configured to slidably engage said second member, wherein said radial seal has a thickness, and a length that is from about 1 to about 15 times greater than said thickness. In various embodiments, the seal is formed of a rubber composition comprising a vulcanized fluorocarbon elastomer dispersed in a matrix of a thermoplastic polymeric material. In various embodiments, the matrix forms a continuous phase and the vulcanized elastomeric material is in the form of particles forming a non-continuous phase. The compositions may be made by combining a curative, an uncured fluorocarbon elastomer, and a thermoplastic material, and heating the mixture to effect vulcanization of the elastomeric material, while applying mechanical energy.
Levels of perfluorocarboxylates (PFCAs) in biological compartments have been known for some time but their transport routes and distribution patterns are not properly elucidated. The opinions diverge whether the exposure of the general population occurs indirect through precursors or direct via PFCAs. Previous results showed that ski wax technicians are exposed to levels up to 92 000 ng/m(3) of 8:2 fluorotelomer alcohol (FTOH) via air and have elevated blood levels of PFCAs. Blood samples were collected in 2007-2011 and analyzed for C(4)-C(18) PFCAs, 6:2, 8:2 and 10:2 unsaturated fluorotelomer acids (FTUCAs) and 3:3, 5:3 and 7:3 fluorotelomer acids (FTCAs) using UPLC-MS/MS. Perfluorooctanoic acid (PFOA) was detected in levels ranging from 1.90 to 628 ng/mL whole blood (wb). Metabolic intermediates 5:3 and 7:3 FTCA were detected in all samples at levels up to 6.1 and 3.9 ng/mL wb. 6:2, 8:2 and 10:2 FTUCAs showed maximum levels of 0.07, 0.64 and 0.11 ng/mL wb. Also, for the first time levels of ...
Microbubble (MB) contrast agents have positively impacted the clinical ultrasound (US) community worldwide. Their use in molecular US imaging applications has been hindered by their limited distribution to the vascular space. Acoustic droplet vaporization (ADV) of nanoscale superheated perfluorocarbon nanodroplets (NDs) demonstrates potential as an extravascular contrast agent that could facilitate US-based molecular theranostic applications. However these agents are metastable and difficult to manufacture with high yields. Here, we report a new formulation technique that yields reliable, narrowly dispersed sub-300 nm decafluorobutane (DFB) or octafluoropropane (OFP)-filled phospholipid-coated NDs that are stable at body temperature, using small volume microfluidization. Final droplet concentration was high for DFB and lower for OFP (,10¹² vs. ,10¹⁰ NDs per mL). Superheated ND stability was quantified using tunable resistive pulse sensing (TRPS) and dynamic light scattering (DLS). DFB NDs ...
EWGs Tap Water Database Perfluorohexane sulfonate (PFHXS) results for City of Donna | Perfluorohexane sulfonate (PFHXS). Find out what is in your tap water
Biotech Support Group Release: Lipid Removal From Docetaxel-Prodrug In Perfluorocarbon Nanoparticles By Sample Pretreatment Using Cleanascite - read this article along with other careers information, tips and advice on BioSpace
Page contains details about perfluorocarbon nanoparticles . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com
We aim to produce emulsions that can act as contrast agents and drug carriers for cancer imaging and therapy. To increase tumor detection and decrease drug side effects, it is desirable to take advantage of the enhanced permeability and retention effect that allows nanoparticles to accumulate in tumor tissues. To do so, the emulsion droplets need to be small enough and stable over time in addition to enhancing image contrast and carrying a drug payload. In the present study, we have investigated the properties and potentiality as theranostic agents of perfluorocarbon emulsions stabilized by a biocompatible fluorinated surfactant called FTAC. To obtain better control of our system, the synthesis of those surfactants was studied and their physico-chemical properties were explored in different configurations such as micelles, in the perfluorocarbon droplet shell and at water/air and water/perfluorocarbon interfaces. The originality of this work lies in the determination of numerous characteristics of
Gas is widely used in vitreoretinal surgery. It is a valuable tool to treat difficult retinal detachments and severe cases of proliferative vitreous retinopathy.1 Gas mediated pupillary block and iridocorneal apposition are known complications in aphakic eyes that underwent vitreoretinal surgery.2-4 We report a case of a phakic patient with an acute pupillary block glaucoma related to the migration of perfluoropropane (C3F8) into the anterior chamber. We are unaware of previous reports on this complication, and a Medline search found no literature on this topic.. ...
While fluorochemicals have been detected all over the world and in wastewater treatment plants, the effect of wastewater effluent on the receiving waters has not been evaluated. In the first study, the mass flow of fluorochemicals emanating from wastewater treatment plants along the Glatt River in Switzerland was evaluated. The fluorochemical concentrations in daily composite samples of river water and wastewater were measured using LC/MS/MS. On average, the seven wastewater treatment plants proved ineffective in completely removing fluorochemicals from the influent and in some individual cases, the effluent concentrations of fluorochemicals were elevated when compared to the influent. Fluorochemical concentrations in wastewater were dominated by PFOS followed by PFHxS and PFOA; PFOS was detected in 100% of the samples. In the Glatt River, PFOS, PFOA and PFHxS were detected in all samples. Mass flows were determined and showed that the mass loading from the treatment plants is additive and that ...
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Cis-2-butene is a colorless, flammable, liquefied gas with a slight aromatic odor. Electronic Fluorocarbons offers a wide range of cylinder sizes.
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A major obstacle in the monitoring and treatment of neurological diseases is the blood brain barrier (BBB), a semipermeable barrier that prevents the delivery of many therapeutics and imaging contrast agents to the brain. In this work, we explored the possibility of laser-activated perfluorocarbon nanodroplets (PFCnDs) to open the BBB and deliver agents to the brain tissue.
Exposure of animals to perfluorooctanoic acid (PFOA), a surfactant used in emulsion polymerization processes causes early pregnancy loss, delayed growth and development of fetuses. The mechanisms of action are largely unknown. We studied the effect of PFOA on implantation using an in vitro spheroid-endometrial cell co-culture model. PFOA (10-100. μM) significantly reduced Jeg-3 spheroid attachment on RL95-2 endometrial cells. PFOA also suppressed β-catenin expression in Jeg-3 cells. The Wnt agonist Wnt3a stimulated β-catenin expression in Jeg-3 cells and reversed the PFOA suppression of the spheroid attachment. The putative PFOA receptors (PPARα, β, γ) present in both cell lines were not affected by PFOA (0.01-100. μM). The PPARα antagonist MK886 restored the β-catenin and E-cadherin expression levels in Jeg-3 cells and reversed the suppression of the spheroid attachment caused by PFOA. Taken together, PFOA suppresses spheroid attachment through PPARα and Wnt signaling pathways via down
Use of second-generation perflutren-based echocardiographic contrast agents (perflutren) is currently contraindicated in patients with known right-to-left, bidirectional, or transient right-to-left intracardiac shunts (intracardiac shunts) according to the U.S. Food and Drug Administration. This contraindication is primarily a result of concerns related to neurological complications and/or systemic embolism from animal data describing entrapment of perflutren lipid microspheres (,5 μm in diameter) within small arterioles and capillaries in skeletal muscles after intra-arterial injection. To date, no definitive evidence demonstrates patient safety concerns from perflutren use in humans with intracardiac shunts. We sought to evaluate the association between perflutren use and adverse events in these patients.. A retrospective cohort study was performed to evaluate the association of perflutren use (Definity, Lantheus Medical Imaging, North Billerica, Massachusetts; Optison, GE Healthcare, ...
Perfluorinated compounds (PFCs), widely used in manufactured products such as non-stick cookware, waterproof clothing, and fast-food packaging, were associated with lowered immune response to vaccinations in children in research led by Philippe Grandjean of the Harvard School of Public Halth (HSPH).. The study appears in the Jan. 25 issue of the Journal of the American Medical Association (JAMA).. Routine childhood immunizations are a mainstay of modern disease prevention. The negative impact on childhood vaccinations from PFCs should be viewed as a potential threat to public health, said Grandjean, adjunct professor of environmental health at HSPH and the reports lead author.. PFCs have thousands of industrial and manufacturing uses. Most Americans have the chemical compounds in their bodies. Prior studies found that PFC concentrations in mice similar to those found in people suppressed immune response, but the adverse effects on people had been poorly documented.. The researchers analyzed ...
Medical devices implanted in the body or in contact with flowing blood faces two critical challenges that can threaten the life of the patient the device is meant to help - blood clotting and bacterial infection. Researchers from the Wyss Institute for Biologically Inspired Engineering at Harvard University have developed a new surface coating for medical devices using FDA-approved materials. The super-repellent coating can be adhered to existing, approved medical devices. In a two??step surface??coating process, the researchers chemically attached a monolayer of perfluorocarbon, which is similar to Teflon. Then they added a layer of liquid perfluorocarbon, which is widely used in medicine for applications such as eye surgery. The team calls the tethered perfluorocarbon plus the liquid layer a Tethered??Liquid Perfluorocarbon surface, or TLP for short. The coating successfully repelled blood from more than 20 medically relevant substrates the team tested - made of plastic to glass and metal - and
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PFOA, PFOS and other PFASs are widespread around the globe, primarily due to their current and/or historical manufacturing, processing and use here in the U.S. and internationally. They are widespread in part because they are persistent in the environment - that is, they do not break down when exposed to air, water or sunlight. As a result, people may become exposed to PFASs manufactured months or years in the past.. Due to their persistence, PFASs can travel long distances through the air; monitoring in the Arctic has shown levels of PFASs in air, water, and living things. As a result, people may become exposed to low levels of PFASs manufactured or emitted from production facilities thousands of miles away.. Because these chemicals have been used in an array of consumer products, most people have been exposed to low levels of them. Studies have found PFOS and PFOA in blood samples of humans and wildlife nationwide. Using data from CDCs 2003-2004 National Health and Nutrition Examination ...
Less] Poly- and perfluoroalkyl substances (PFASs) have been detected in drinking water at relatively high . . . [More] Poly- and perfluoroalkyl substances (PFASs) have been detected in drinking water at relatively high concentrations throughout the world which has led to implementation of regulatory guidelines for specific PFASs in drinking water in several European countries and in the U.S. The Swedish National Food Agency has determined that the drinking water of over one third of the countrys municipal consumers is at risk or already affected by PFAS contamination. The present study investigated the effects of perfluorocarbon chain length, functional group and isomer structure (branched or linear) on removal of multiple PFASs using granular activated carbon (GAC, Filtrasorb(®) 400) and anion exchange (AE, Purolite(®) A600) column experiments. The removal of 14 different PFASs, i.e. the C3C11, C14 perfluoroalkyl carboxylic acids (PFCAs) (PFBA, PFPeA, PFHxA, PFHpA, PFOA, PFNA, PFDA, PFUnDA, ...
Daikin Industries Ltd is a leading manufacturer of fluoro chemical products possessing unique properties demonstrating superior resistance to heat, chemicals, and weather while giving outstanding functionality in sliding, anti-stick, and water repellency applications. The Daikin Chemicals Division manufactures and sells a variety of producs such as fluorocarbon resins, fluoroelastomers, paints, coatings, mold release agents, fluorinated intermediates, fluorocarbons, semiconductor etching agents, and advanced fluorocarbon resin air filters.
Daikin Industries Ltd is a leading manufacturer of fluoro chemical products possessing unique properties demonstrating superior resistance to heat, chemicals, and weather while giving outstanding functionality in sliding, anti-stick, and water repellency applications. The Daikin Chemicals Division manufactures and sells a variety of producs such as fluorocarbon resins, fluoroelastomers, paints, coatings, mold release agents, fluorinated intermediates, fluorocarbons, semiconductor etching agents, and advanced fluorocarbon resin air filters.
They behave like biological neurons, including low power usage and dense scaling. This apparently represents IBMs artificial neurons, though Im not entirely convinced. I guess the red/yellow/orange/blue bits are the phase-change material? IBM IBM Research in Zurich has created the worlds first artificial nanoscale stochastic phase-change neurons. IBM has already created a population of 500…
Dont drink the water. Thats what people from Flint, Mich., to a little New York town called Hoosick Falls have been hearing.. In Flint, its lead. We all know what that is. In Hoosick Falls, its perfluorooctanoic acid (PFOA). Never heard of it? Well, its probably in your kitchen or closet, and almost definitely in your body.. PFOA is a type of perfluoroalkyl acid (PFAA), a group of chemicals studied by Laura MacManus-Spencer. And PFAAs are used in everything from Gore-Tex clothing and Duponts StainMaster carpet to non-stick pans and coatings for microwave popcorn bags.. PFAAs are everywhere in the environment. Every U.S resident has a measurable amount of PFAAs in their blood, she said. And literally every organism that scientists pluck out of the environment has these chemicals in their blood.. These chemicals are not known to be very acutely toxic (it wont cause illness immediately), unless youre exposed to really high concentrations, MacManus-Spencer continued. The concern is ...
Perflutren protein type A microsphere is an ultrasound contrast agent. Ultrasound contrast agents are used to help provide a clear picture during ultrasound. Ultrasound is a special kind of diagnostic procedure. It uses high-frequency sound waves to create images or pictures of certain areas inside the body. The sound waves produced by the ultrasound equipment can be reflected (bounced off) by different parts of the body, such as, the heart. As the sound waves return they are electronically converted into images on a television screen. Unlike x-rays, ultrasound does not involve ionizing radiation. The albumin microspheres sonicated preparation contains very small gas-filled albumin microspheres that reflect the sound waves and help create a better picture. This medicine is to be given only by or under the direct supervision of a doctor with specialized training in ultrasound procedures. This product is available in the following dosage forms:. ...
Scientists have, for the first time, characterized so-called quantum vortices that swirl within tiny droplets of liquid helium. The research, led by scientists at the US Department of Energys Lawrence Berkeley National Laboratory , the University of Southern California, and SLAC National Accelerator Laboratory, confirms that helium nanodroplets are in fact the smallest possible superfluidic objects and opens new avenues to study quantum rotation.
Free electron lasers (FELs) offer the unprecedented capability to study reaction dynamics and image the structure of complex systems. When multiple photons are absorbed in complex systems, a plasma-like state is formed where many atoms are ionized on a femtosecond timescale. If multiphoton absorption is resonantly-enhanced, the system becomes electronically-excited prior to plasma formation, with subsequent decay paths which have been scarcely investigated to date. Here, we show using helium nanodroplets as an example that these systems can decay by a new type of process, named collective autoionization. In addition, we show that this process is surprisingly efficient, leading to ion abundances much greater than that of direct single-photon ionization. This novel collective ionization process is expected to be important in many other complex systems, e.g. macromolecules and nanoparticles, exposed to high intensity radiation fields.. Keywords: Free electron laser ; ionization ; clusters. ...
The rotational spectra of molecules observed in liquid helium-4 nanodroplets typically display substantially reduced rotational constants (except for the very lightest rotors), which implies that helium motion contributes to the effective moment of inertia of the molecules even though the damping is very small. For small droplets ( $N \le 100$), Monte Carlo calculations can give unbiased predictions for the rotational excitation energies that have been found to be in quantitative agreement with experiment. More approximation model calculations are still of value as they allow treatment of droplets of the size range of most experiments ($N \sim 10^3 - 10^4$) and perhaps provide more insight into the nature of the dynamics. In this talk, I will review work we have done on hydrodynamic calculations and more even more highly simplified ``toy models ...
Researchers have shed new light on the heterogeneous nature of a polar organic liquid mixed with water. They used laser light as a tool that allowed them to demonstrate the existence of stable nanodroplets of tetrahydrofuran in the bulk of aqueous electrolyte solutions and to develop a new theory that explains the spontaneous generation of heterogeneous nanoparticles in aqueous solutions of ...
Spectroscopy of doped superfluid helium nanodroplets (He$_N$) gives information about the influence of this cold, chemically inert, and least interacting matrix environment on the excitation and relaxation dynamics of dopant atoms and molecules \footnote{C. Callegari and W. E. Ernst, Helium Droplets as Nanocryostats for Molecular Spectroscopy - from the Vacuum Ultraviolet to the Microwave Regime, in Handbook of High-Resolution Spectroscopy, eds. M. Quack and F. Merkt, John Wiley \& Sons, Chichester, 2011.}. We present the results from laser induced fluorescence (LIF), photoionization (PI), and mass spectroscopy of Cr \footnote{A. Kautsch, M. Koch, and W. E. Ernst, J. Phys. Chem. A, \textbf{117} (2013) 9621-9625, DOI: 10.1021/jp312336m} and Cu \footnote{F. Lindebner, A. Kautsch, M. Koch, and W. E. Ernst, Int. J. Mass Spectrom. (2014) in press, DOI: 10.1016/j.ijms.2013.12.022} doped He$_N$. From these results, we can draw a comprehensive picture of the complex behavior of such transition metal ...
According to Chief Business Officer, David Wilson, this transition ratchets up the expenses, but clinical trials are the only way to determine the therapeutic potential of the NuvOx platform and to garner the interest of potential collaborators and investors. Now that we are in the clinic this is where the rubber meets the road from a drug development perspective and what Therapeutic Areas the platform will provide benefit. With demonstrated proof-of-concept in humans, we are now ready to start discussions with potential corporate partners and institutional investors, according to Dr. Wilson.. The nanotechnology therapeutic platform is based on unique perfluorocarbon emulsions of dodecafluoropentane (DDFPe). Twenty years ago it was determined that stable nanodroplets of DDFPe could be transformed into microbubbles that were well suited for ultrasound contrast imaging of the cardiovascular system. The product was tested to be safe and effective to the point where a New Drug Application (NDA) ...
EPA is launching a global stewardship program inviting companies to reduce PFOA (Perfluorooctanoic acid) releases and its presence in products by 95 percent by no later than 2010 and to work toward eliminating these sources of exposure five years after that but no later than 2015.. PFOA is an essential processing aid in the manufacture of fluoropolymers, which are used in the manufacture of a wide range of non-stick and stain-resistant surfaces and products. PFOA may also be produced by the breakdown of fluorotelomers, which are used to impart water, stain, and grease resistance to carpets, paper and textile.. PFOA is persistent in the environment, it has been detected in low levels in wildlife and humans, and animal studies conducted have indicated effects of concern.. The science is still coming in, but the concern is there so acting now to minimize future releases of PFOA is the right thing to do for our environment and our health, said Susan B. Hazen, acting assistant administrator of ...
Concentrations of perfluorinated chemicals (PFCs) were measured in surface waters and sediments from the Coosa River watershed in northwest Georgia, USA, to examine their distribution downstream of a suspected source. Samples from eight sites were analyzed using liquid chromatography‐tandem mass spectrometry. Sediments were also used in 28‐d exposures with the aquatic oligochaete, Lumbriculus variegatus, to assess PFC bioaccumulation. Concentrations of PFCs in surface waters and sediments increased significantly below a land‐application site (LAS) of municipal/industrial wastewater and were further elevated by unknown sources downstream. Perfluorinated carboxylic acids (PFCAs) with eight or fewer carbons were the most prominent in surface waters. Those with 10 or more carbons predominated sediment and tissue samples. Perfluorooctane sulfonate (PFOS) was the major homolog in contaminated sediments and tissues. This pattern among sediment PFC concentrations was consistent among sites and reflected
Perfluoroalkyl acids (PFAAs) are man-made chemicals. Their unique properties make them beneficial for a wide range of industrial and consumer applications, such as constituents in fire fighting foams, hydraulic oils and food packaging materials.PFAAs have shown to be highly persistent in the environment, and the toxicological potential of long chain PFAA homologues is of a concern. International regulation and voluntary actions by the industry have been implemented and led to reduced primary emissions of PFAAs to the environment. However, the concentrations of some PFAAs in e.g. birds from the Baltic Sea are still very high and of ecotoxicological concern. Measures to reduce the PFAA contamination require an understanding of the sources and how the PFAAs are being transported in the environment.In this licentiate thesis a mass balance was assembled for perfluorohexanoic acid (PFHxA), perfluorooctanoic acid (PFOA), perfluorodecanoic acid (PFDA) and perfluorooctane sulfonic acid (PFOS) in the ...
A process for preparing a fluorocarbon polymer coated substrate includes heating a surface coating containing a fluorocarbon polymer and a copolymer based on vinylidene chloride, the surface coating being on a priming coating containing chromium oxide, or chromium oxide with chromium, such that the heating decomposes the copolymer to etch the priming coating to key the fluorocarbon polymer to the priming coating.
Little is known about factors influencing infant perfluorinated alkyl acid (PFAA) concentrations. Associations between serum PFAA concentrations in 2-4-month-old infants (n = 101) and determinants were investigated by multiple linear regression and general linear model analysis. In exclusively breastfed infants, maternal serum PFAA concentrations 3 weeks after delivery explained 13% (perfluoroundecanoic acid, PFUnDA) to 73% (perfluorohexanesulfonate, PFHxS) of infant PFAA concentration variation. Median infant/maternal ratios decreased with increasing PFAA carbon chain length from 2.8 for perfluoroheptanoic acid and perfluorooctanoic acid (PFOA) to 0.53 for PFUnDA and from 1.2 to 0.69 for PFHxS and perfluorooctanesulfonate (PFOS). Infant PFOA, perfluorononanoic acid (PFNA), and PFOS levels increased 0.7-1.2% per day of gestational age. Bottle-fed infants had mean concentrations of PFAAs 2 times lower than and a mean percentage of branched (%br) PFOS isomers 1.3 times higher than those of ...
https://en.wikipedia.org/wiki/Perfluorooctanoic_acid Perfluorooctanoic acid (PFOA), also known as C8 and perfluorooctanoate, is a synthetic...
Article Perfluorinated chemicals (PFCs) in water purification plants (WPPs) with advanced treatment processes. A series of perfluorinated chemicals (PFCs) surveys were conducted in two water purification plants (WPPs) having ozonation and granular ac...
Article Water matrix effect on UV photodegradation of perfluorooctanoic acid. The widespread detection of perfluorinated compounds (PFCs) in the water environment has been a concern for the last several years, while effluents from wastewater treatmen...
TY - JOUR. T1 - Novel non-targeted analysis of perfluorinated compounds using fluorine-specific detection regardless of their ionisability (HPLC-ICPMS/MS-ESI-MS). AU - Azua Jamari, Nor Laili. AU - Dohmann, Jan Frederik. AU - Raab, Andrea. AU - Krupp, Eva M.. AU - Feldmann, Joerg. N1 - NLAJ thanks the Malaysian Government (Grant number: RG12824-10) and the National Defence University of Malaysia for financial support throughout the study period, while JFD thanks the Erasmus program of the EU. Special thanks to the Swedish Research Council (Grant number: FORMAS 1397306) for additional financial support in this project.. PY - 2019/4/11. Y1 - 2019/4/11. N2 - Although perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA) have been phased out, there is a plethora of per- or polyfluoroalkyl substances (PFAS) generated and only a small number of these compounds are currently being monitored in environmental and biological sample using molecular mass spectrometry (MS). Total fluorine ...
1 Perfluorooctanoic Acid (PFOA): A Global Water Contaminant Brandon M. Montes, Ernesto M. Garcia and Antonio F. Machado Department of Environmental and Occupational Health, California State University, Northridge Found in the blood of nearly all American citizens at an average level of.04 ppm. PFOA is very persistent with a half-life of 2.5-3.5 years in the human body Perfluoroalkyls are mobile in soil and leach into groundwater PFOA can now be traced in some foods, drinking water, and in dust found inside regular homes. PFOA is otherwise known as C8 because of its 8 carbon chain (C8HF15O2) Perfluoroalkyls are human-made substances that do not occur naturally in the environment. Manufacturing started in 1947 by 3M Used as part of the process of making products containing fluoropolymers Fluoropolymers contained the property of both being lipophilic and hydrophobic Used to make non-stick pans, water/stain resistant materials, and water repellant aerosolized applicators. Although final products are ...
NGO comments on Draft Screening Assessment & Risk Management Scope Documents for Perfluorooctanoic Acid (PFOA), its Salts, and its Precursors, and Long-Chain (C9-C20) Perfluorocarboxylic Acids (PFCAs), their Salts, and their Precursors A Response to Canada Gazette Part I, Vol. 144, No. 44 - October 30, ...
http://www.ntn.org.au/featured/firefighters-community-and-environment-at-risk-from-perfluorinated-chemcialsFirefighters, community and environment at risk from perfluorinated chemcialsNTN has released its new report on the Persistence and Toxicity of Perfluorinated Compounds in Australia.
TY - JOUR. T1 - Mesoporous Fluorinated Metal-Organic Frameworks with Exceptional Adsorption of Fluorocarbons and CFCs. AU - Chen, Teng Hao. AU - Popov, Ilya. AU - Kaveevivitchai, Watchareeya. AU - Chuang, Yu Chun. AU - Chen, Yu Sheng. AU - Jacobson, Allan J.. AU - Miljanic, Ognjen. N1 - Publisher Copyright: © 2015 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim. Copyright: Copyright 2016 Elsevier B.V., All rights reserved.. PY - 2015/11/16. Y1 - 2015/11/16. N2 - Two mesoporous fluorinated metal-organic frameworks (MOFs) were synthesized from extensively fluorinated tritopic carboxylate- and tetrazolate-based ligands. The tetrazolate-based framework MOFF-5 has an accessible surface area of 2445m2 g-1, the highest among fluorinated MOFs. Crystals of MOFF-5 adsorb hydrocarbons, fluorocarbons, and chlorofluorocarbons (CFCs) - the latter two being ozone-depleting substances and potent greenhouse species - with weight capacities of up to 225 %. The material exhibits an apparent preference for the ...
Paola Irato, Sara Trabucco and Laura Tallandini-Emerging Contaminants Such as Perfluorinated Compounds: Toxicity andOxidative Stress
TY - JOUR. T1 - Perfluorooctane sulfonate-induced hepatic steatosis in male sprague dawley rats is not attenuated by dietary choline supplementation. AU - Bagley, Bradford D.. AU - Chang, Shu Ching. AU - Ehresman, David J.. AU - Eveland, Alan. AU - Zitzow, Jeremiah D.. AU - Parker, George A.. AU - Peters, Jeffrey M.. AU - Wallace, Kendall B.. AU - Butenhoff, John L.. N1 - Publisher Copyright: © The Author 2017. Published by Oxford University Press on behalf of the Society of Toxicology. All rights reserved.. PY - 2017/12/1. Y1 - 2017/12/1. N2 - Perfluorooctane sulfonate (PFOS) is an environmentally persistent chemical. Dietary 100ppm PFOS fed to male mice and rats for 4 weeks caused hepatic steatosis through an unknown mechanism. Choline deficient diets can cause hepatic steatosis. A hepatic choline:PFOS ion complex was hypothesized to cause this effect in mice. This study tested whether dietary choline supplementation attenuates PFOS-induced hepatic steatosis in rats. Sprague Dawley rats ...
In todays society, heart surgery directly or indirectly affects nearly all individuals, yet most are unaware that a blood substitute is often responsible for delivering oxygen to the patients body during the procedure. Specifically, a blood substitute known as Fluosol DA has been approved by the Food and Drug Administration for use during coronary angioplasty [5]. It is representative of perfluorocarbons (PFCs), the second class of blood substitutes. Fluorocarbons are straight chain molecules that consist of carbon and fluorine [8]. They are known for their capacity to carry both oxygen and carbon dioxide without actually binding to the gas molecules. Thus, their application extends from solely delivering oxygen to also carrying waste to the lungs for removal from the body [5]. Fluosol DA serves as one of the original PFCs, and it is comprised of 20 percent fluorocarbon [6]. A group of PFCs referred to as the new perflourochemicals has recently been developed. They include compounds such as ...
Perfluorooctanesulfonyl fluoride (POSF, C8F17SO2F) is used to create applications for surfactants and paper, packaging, and surface (e.g., carpets, textiles) protectants. Such POSF-based products or their residuals may degrade or metabolize to PFOS (C8F17SO3-). PFOS concentrates in liver and serum a …
TY - JOUR. T1 - PFAS exposure and overweight/obesity among children in a nationally representative sample. AU - Geiger, Sarah Dee. AU - Yao, Ping. AU - Vaughn, Michael G.. AU - Qian, Zhengmin. N1 - Publisher Copyright: © 2020 Elsevier Ltd. PY - 2021/4. Y1 - 2021/4. N2 - Purpose: Perfluoroalkyl substances (PFASs) are a class of manmade chemicals commonly used in consumer product manufacturing. Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) are two of the most highly studied PFASs. Both are present in the blood of the most Americans. PFASs are associated with intermediate cardiovascular disease (CVD) outcomes, but their relationship with obesity, a risk factor for intermediate and advanced CVD, remains largely unconfirmed. In this context, we aimed to explore the relationship between PFASs and both overweight/obesity and abdominal obesity among children. Methods: We examine associations between PFOA and PFOS levels, and Body Mass Index (BMI) and waist circumference (WC) in a ...
A survey on seasonal concentration changes of perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) was performed for surface water in Lake Biwa (14 sites) from February to November in 20
There is increasing global concern regarding the health impacts of perfluoroalkyl and polyfluoroalkyl substances (PFAS), which are emerging environmental endocrine disruptors. Results from previous epidemiological studies on the associations between PFAS exposure and sex hormone levels are inconsistent. We examined the associations between serum PFAS compounds (PFDeA, PFHxS, PFNA, PFOA, PFOS) and sex hormones, including total testosterone (TT), free testosterone (FT), estradiol (E), and serum hormone binding globulin (SHBG). After adjusting for potential confounders, PFDeA, PFOS, and PFHxS exposures were significantly associated with increased serum testosterone concentrations in males. PFDeA, PFOA, and PFOS exposures were positively correlated with FT levels in 20-49-year-old women, while PFOS exposure was negatively associated with TT levels in 12-19-year-old girls. PFAS exposure was negatively associated with estradiol levels including: PFDeA in all females, PFHxS, PFNA, PFOS, and PFOA in 12-19-year
Several environmental contaminants, such as polychlorinated biphenyls, dioxins, bisphenol A and phthalates, have been linked to diabetes. We therefore investigated whether other kinds of contaminants, perfluoroalkyl substances (PFAS), also called perfluorinated compounds (PFCs), are also associated with diabetes. The Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study investigated 1,016 men and women aged 70 years. Seven PFAS were detected in almost all participant sera by ultra-high performance liquid chromatograph/tandem mass spectrometry. Diabetes was defined as use of hypoglycaemic agents or fasting glucose , 7.0 mmol/l. 114 people had diabetes. In the linear analysis, no significant relationships were seen between the seven PFAS and prevalent diabetes. However, inclusion of the quadratic terms of the PFAS revealed a significant non-linear relationship between perfluorononanoic acid (PFNA) and diabetes, even after adjusting for multiple confounders (OR 1.96, 95% CI ...
TY - JOUR. T1 - Molecular design of liquid crystalline poly(ester-amide)s with perfluoroalkyl spacers. AU - Teoh, May May. AU - Chung, Tai-Shung. AU - Cheng, Si Xue. AU - Lin, Ting Ting. AU - Pramoda, K. P.. PY - 2004/6/1. Y1 - 2004/6/1. N2 - We have introduced a series of perfluoroalkyl dicarboxylic acids with different lengths of fluorinated aliphatic segments into the 2,6-acetoxynaphthoic acid (ANA) and acetoxy acetanilide (AAA) systems; and their effects on the evolution of liquid crystal texture and liquid crystallinity have been investigated. The perfluoroalkyl dicarboxylic acids are tetrafluorosuccinic acid (TFSA, n = 2), hexafluoroglutaric acid (HFGA, n = 3), perfluorosuberic acid (PFSUA, n = 6) and perfluorosebacic acid (PFSEA, n = 8). Computational results based on the RIS Metropolis Monte Carlo method indicate that the ANA/AAA/perfluoroalkyl system may form thermotropic liquid crystalline polymers (LCPs) because the calculated persistence ratios are greater than 6.42. Computational ...
DOI: 10.1016/j.envpol.2020.115908. Perfluoroalkyl acids (PFAAs) are widely used in industrial production and daily life because of their unique physicochemical properties, such as their hydrophobicity, oleophobicity, surface activity, and thermal stability. Perfluorosulfonic acids (PFSAs) and perfluorocarboxylic acids (PFCAs) are the most studied PFAAs due to their global occurrence. PFAAs are environmentally persistent, toxic, and the long-chain homologs are also bioaccumulative. Exposure to PFAAs may arise directly from emission or indirectly via the environmental release and degradation of PFAA precursors. Precursors themselves or their conversion intermediates can present deleterious effects, including hepatotoxicity, reproductive toxicity, developmental toxicity, and genetic toxicity. Therefore, exposure to PFAA precursors constitutes a potential hazard for environmental contamination. In order to comprehensively evaluate the environmental fate and effects of PFAA precursors and their ...
Fluorocarbon polymer, any of a number of organic polymers whose large, multiple-unit molecules consist of a chain of carbon atoms to which fluorine atoms are appended. Owing to the presence of the highly polar fluorine atoms, which form extremely strong bonds with the carbon chain and resist
Williams, Faith M., Draffan, G. H., Dollery, C. T., Clark, J. C., Palmer, A. J., and Vernon, P. (1974).Thorax, 29, 99-103. Use of 18F labelled fluorocarbon-11 to investigate the fate of inhaled fluorocarbons in man and in the rat. The distribution and elimination of 18F labelled fluorocarbon-11 has been followed in a group of rats killed after air breathing following six minutes exposure to 18F fluorocarbon-11. Whole body and individual organ count rates were measured. In four volunteers the fate of 18F labelled fluorocarbon-11 was followed by both whole body counting and gamma camera measurement of the activity in the lung and mouth region after inhalation from a specially loaded aerosol dispenser.. In the rat there was a high initial level in high blood flow organs and in the adrenals and fat: the level in blood and high blood flow organs fell rapidly. Elimination from fat was slow but the adrenal level had fallen within one hour. The fall in whole body count rate was similar to that in ...
A metered dose inhaler having part or all of its internal surfaces coated two or more times with a polymer comprising one or more fluorocarbon polymers, optionally in combination with one or more non-
IN NOVEMBER OF 1984 THE PRESIDENT SIGNED INTO LAW A SET OF FAR-REACHING AMENDMENTS TO THE RESOURCE CONSERVATION AND RECOVERY ACT OF 1976. UNDER THE NEW LAW, LAND DISPOSAL OF ALL HAZARDOUS WASTES IS TO BE BANNED OVER THE NEXT FIVE YEARS. WASTE REDUCTION, RECYCLE, AND INCINERATION ARE EMPHASIZED. PARTICULARLY TARGETED ARE WASTE STREAMS CONTAINING HALOG ENATED SOLVENTS AND ARSENIC DUE TO THE THREATS THESE MA MATERIALS POSE TO HUMAN HEALTH AND TO THE ENVIRONMENT. PRESENT TECHNOLOGY FOR RECOVERY AND RECYCLE OR FOR THE INCINERATION OF HAZARDOUS HALOGENATED ORGANIC WASTES CANNOT BE APPLIED TO ALL SUCH MATERIALS. STREAMS WHICH CONTAIN COMPLEXAZEOTROPIC MIXTURES OR ARE CORROSIVE, HIGHLY REACTIVE, OR ACIDIC ARE NOT COMPATIBLE WITH CURRENT DISTILLATION/SEPAR ARATION OR INCINERATION EQUIPMENT. THE SPENT CATALYST FROM FLUOROCARBON MANFUCTURING PROCESSES IS AN EXCELLENT EXAMPLE OF A HAZARDOUS AND TOXIC WASTE STREAM WHICH WILL BE TARGETEDEARLY BY THE NEW ACT AND FOR WHICH CURRENT DISPOSAL TECHNO NOLOGY IS ...
Fluorocarbon Rubber (FKM Rubber) is a specialized compound with excellent high heat, oil resistance and low compression set. Flourocarbon rubber also has excellent abrasion resistance and the ability to hold a seal under hard vacuum.
Tali fluorocarbon atau singkatannya, FC, bagi saya, merupakan jenis tali yang paling sesuai untuk dijadikan tali perambut. Ramai yang masih tertanya-tanya apakah kelebihan tali jenis ini jika dibandingkan dengan tali jenis monofilament yang jauh lebih murah harganya untuk dijadikan tali perambut. Gambarajah di bawah
TY - JOUR. T1 - Thermal properties and crystallization dynamics of a phase-change alloy for write-once optical data storage. AU - Fischer, Gerd M.. AU - Medower, Brian. AU - Revay, Robert. AU - Mansuripur, Masud. PY - 2002/1/1. Y1 - 2002/1/1. N2 - Using a two-laser static tester, we measured the crystallization temperature and the thermal conductivity of a phase-change alloy thin film used in write-once-read-many media of optical data storage. The experimental technique, in general, and the calibration procedures, in particular, are described. The measurement results are used as entry points into numerical calculations that ultimately yield estimates of the material parameters. Valuable information about the dynamics of mark formation (i.e., localized crystallization) in amorphous phase-change alloy films is obtained from the observed variations of the sample reflectance under short-pulse and long-pulse recording conditions. The dependence of these reflectance variations on the laser pulse power ...
Pregnant women are an especially important population to monitor for environmental exposures given the vulnerability of the developing fetus. During pregnancy and lactation chemical body burdens may change due to the significant physiological changes that occur. Developmental exposures to some persistent organic pollutants (POPs) have been linked with adverse health outcomes. First trimester maternal and cord blood plasma concentrations of several POPs including polychlorinated biphenyls (PCBs), organochlorine pesticides (OCs), polybrominated diphenyl ethers (PBDE)s and perfluoroalkyl substances (PFASs) were measured in samples from 1983 pregnant women enrolled in the Maternal-Infant Research on Environmental Chemicals (MIREC) cohort. Predictors of exposure were also identified. In maternal plasma, there was |90 % detection for the perfluoroalkyl substances (PFASs) perfluorooctanoic acid (PFOA), perfluoroctane sulfonate (PFOS), perfluorohexane sulfonate (PFHxS), and dichlorodiphenyldichloroethylene (DDE
The study reviews the current state of knowledge regarding the biotransformation of fluorotelomer-based compounds, with a focus on compounds that ultimately degrade to form perfluoroalkyl carboxylates (PFCAs). Most metabolism studies have been performed with either microbial systems or rats and mice, and comparatively few studies have used fish models. Furthermore, biotransformation studies thus far have predominately used the 8:2 fluorotelomer alcohol (FTOH) as the substrate. However, there have been an increasing number of studies investigating 6:2 FTOH biotransformation as a result of industrys transition to shorter-chain fluorotelomer chemistry. Studies with the 8:2 FTOH metabolism universally show the formation of perfluorooctanoate (PFOA) and, to a smaller fraction, perfluorononanoate (PFNA) and lower-chain-length PFCAs. In general, the overall yield of PFOA is low, presumably because of the multiple branches in the biotransformation pathways, including conjugation reactions in animal ...
Link: Shabalina Irina G, Kalinovich AV, Cannon B, Nedergaard J (2015) Event: MiP2015 The environmental pollutants perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) are degradation products of polyfluorinated surfactants and polymers that due to their unique surface-active properties, the stability of their C-F bonds and their thermal resistivity, are utilized in a wide variety of products, including fire-fighting foams, lubricants, paints, cosmetics and ski-wax. PFOS/PFOA cause a dramatic reduction in the size of the major adipose tissue depots when they are added to the food of mice. A large part of the effect of PFOA/PFOS on food intake was dependent on the presence of the uncoupling protein 1 (UCP1) in the brown adipose tissue [1]. We have examined here the possibility that PFOA/PFOS can directly (re)activate UCP1 in isolated mouse brown-fat mitochondria. In wildtype brown-fat mitochondria, PFOS and PFOA overcame GDP-inhibited thermogenesis, leading to increased oxygen ...
Per- and polyfluoroalkyl substances (PFAS) are a group of synthetic compounds found in a variety of household and industrial products. The two most studied compounds in this family, perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS), have been associated with a range of health concerns. The following webinar recording describes two pilot projects designed to measure human PFAS exposures undertaken by the Pennsylvania Department of Health and the New York State Department of Health. It focuses on the states use of the PFAS Exposure Assessment Technical Tools (PEATT)-a guidance document developed by CDC and the Agency for Toxic Substances and Disease Registry to measure human PFAS exposures through drinking water sources. Results from PEATT allow health officials to estimate levels of exposure for an entire affected community, not just those individuals tested. The PEATT also provides guidance on how to share results with affected communities.Read More ». ...
The European Commission this year will consider a proposal to restrict the manufacture or sale of perfluorohexane sulfonic acid (PFHxS), its salts, or substances that degrade into PFHxS. These chemicals are used as water and stain repellents in textile treatment, according to the European Chemicals Agency (ECHA). They are part of a group known as per- and polyfluoroalkyl substances (PFAS) that are highly persistent in the environment. PFHxS is highly bioaccumulative and has been detected in human blood and in wildlife in the Arctic and other remote places. Use of PFHxS and its related compounds has declined in recent years, ECHA says, adding that current annual emissions of these substances in the EU are estimated at about 0.42 metric tons. Norway initiated the proposal to restrict PFHxS and its related compounds, with the goal to prevent their use in place of perfluorooctanesulfonic acid, which is already banned in the European Union, or perfluorooctanoic acid, which will be prohibited there as ...
FLUOROCARBON EMULSION STABILIZING SURFACTANTS - Surfactants (e.g., fluorosurfactants) for stabilizing aqueous or hydrocarbon droplets in a fluorophilic continuous phase are presented. In some embodiments, fluorosurfactants include a fluorophilic tail soluble in a fluorophilic (e.g., fluorocarbon) continuous phase, and a headgroup soluble in either an aqueous phase or a lipophilic (e.g., hydrocarbon) phase. The combination of a fluorophilic tail and a headgroup may be chosen so as to create a surfactant with a suitable geometry for forming stabilized reverse emulsion droplets having a disperse aqueous or lipophilic phase in a continuous, fluorophilic phase. In some embodiments, the headgroup is preferably non-ionic and can prevent or limit the adsorption of molecules at the interface between the surfactant and the discontinuous phase. This configuration can allow the droplet to serve, for example, as a reaction site for certain chemical and/or biological reactions. In another embodiment, aqueous ...
PFCs are synthetic organic compounds, based on fluorine. Used in stain, heat and water-resistant products (eg Teflon). Toxic to lab animals. Bioaccumulative
Jusko T, Oktapodas M, Palkovi?ová Murinová ?, Babinska K, Babjakova J, Verner MA, DeWitt J, Thevenet-Morrison K, Conka K, Drobná B, Chovancova J, Thurston S, Lawrence BP, Dozier A, Jarvinen K, Patayova H, Trnovec T, Legler J, Hertz-Picciotto I, Lamoree MH. Demographic, Reproductive, and Dietary Determinants of Perfluorooctane Sulfonic (PFOS) and Perfluorooctanoic Acid (PFOA) Concentrations in Human Colostrum. Environmental science & technology.. 2016 Jul 5; 50(13):7152-62. Epub 2016 Jun 14. 5/ ...
3,094,547 PERFLUORQALKYLSULFQNAMIDOALKYL ESTERS OF PHOSPHURUS ACIDS Richard F. Heine, White Bear Lake, Minn, assiguor to Minnesota Mining and Manufacturing Company, St. Paul, Minn, a corporation of Delaware No Drawing. Filed Feb. 6, 1961, Ser. No. 87,060 9 Claims. (Cl. 260-461) This invention relates to a new and useful class of phosphorus-containing fluorocarbon compounds and polymers thereof. The invention also relates to the sizing of fabrics to impart both repellency to water and. resistance to absorption, and soiling by oily and greasy materials, to the coating and impregnation of matrices such as paper and leather, to the provision of certain desirable surfactant properties in polishes and plating baths, and for other purposes. it is therefore an object of this invention to provide phosphorus-containing fluorocarbon compounds and derivatives thereof. it is also an object of this invention to provide a method for preparing phosphorus-containing fluorocarbon compounds and derivatives ...
Non-stick cookware contains several toxic perfluorinated compounds (PFCs) like perfluorooctanoic acid (PFOA), which can cause thyroid disease.
To determine whether exposure to per-and polyfluoroalkyl susbtances at an early developmental stage is associated with risk for autism spectrum disorders.
New research, published today in the journal Environmental Science & Technology, shows that some persistent perfluorinated chemicals (PFCs) can be transferred from mother to infant via breast milk. These chemicals, which have been widely used, are linked to a number of health problems, including negative impacts on immune response to vaccines in children. The research suggests that breast milk is a major source of exposure to some PFCs during infancy, though the researchers emphasise the important benefits of breast milk for babies.. The study looked specifically at a group of PFCs called PFAS chemicals, which have been used in a variety of consumer products, from non-stick frying pans, waterproof clothing, stain-resistant fabrics to food packaging - including in pizza boxes and microwave popcorn bags. See our recent blog on PFCs for more information on their use and potential health impacts.. The new research was carried out in the Faroe Islands between 1997-2000, with blood being analysed for ...
Our study found that increased exposure to PFOA, PFOS, PFNA, and PFHxS was associated with higher odds of irregular and long menstrual cycle and lower risks of menorrhagia in women who plan to be pregnant. In contrast, women with higher levels of PFOA, PFNA, and PFHxS were more likely to have hypomenorrhea.. Two previous studies have evaluated the association between PFOA and PFOS and menstrual irregularity and length. Our results are consistent with those reported in a subset of 1,240 pregnant women randomly selected from the Danish National Birth Cohort (Fei et al. 2009). They found that the risk of irregular menstrual cycle was higher in women exposed to PFOA (15.0% in the upper three quartiles vs. 9.0% in the lowest quartile) and PFOS (14.2% in the upper three quartiles vs. 11.6% in the lowest quartile) (Fei et al. 2009). The INUENDO cohort enrolled 1,623 pregnant women in three countries (Greenland, Poland, and Ukraine) (Lyngsø et al. 2014) and found that PFOA exposure levels were ...
Background Oncolytic virotherapy of tumors is an up-coming, promising therapeutic modality of cancer therapy. Unfortunately, non-invasive techniques to evaluate the inflammatory host response to treatment are rare. Here, we evaluate \(^{19}\)F magnetic resonance imaging (MRI) which enables the non-invasive visualization of inflammatory processes in pathological conditions by the use of perfluorocarbon nanoemulsions (PFC) for monitoring of oncolytic virotherapy. Methodology/Principal Findings The Vaccinia virus strain GLV-1h68 was used as an oncolytic agent for the treatment of different tumor models. Systemic application of PFC emulsions followed by \(^1H\)/\(^{19}\)F MRI of mock-infected and GLV-1h68-infected tumor-bearing mice revealed a significant accumulation of the \(^{19}\)F signal in the tumor rim of virus-treated mice. Histological examination of tumors confirmed a similar spatial distribution of the \(^{19}\)F signal hot spots and \(CD68^+\)-macrophages. Thereby, the ...
PFNA is found in a wide array of consumer products, food, water, and air. Levels of PFNA in the environment continue to increase, and can accumulate over a lifetime. Thyroid hormones are responsible for regulating major processes of the human body. Decreasing levels of thyroid hormones could potentially interfere with essential metabolic processes. Results of this study help researchers better understand the levels of serum PFNA found in the U.S. general population, and adds to the growing body of knowledge of PFNA in relation to thyroid hormone levels.
Per- and polyfluoroalkyl substances (PFAS) are environmental chemicals linked to weight gain and type 2 diabetes.We examined the extent to which PFAS plasma concentrations during pregnancy were associated with postpartum anthropometry and biomarkers.We studied women recruited between 1999-2002 in the Project Viva prospective cohort with pregnancy plasma concentrations of PFAS, including perfluorooctanesulfonic acid (PFOS), perfluorooctanoic acid (PFOA), and 2-(N-ethyl-perfluorooctane sulfonamide) acetic acid (EtFOSAA). Three-year postpartum anthropometry measurements were available from 786-801 women, blood pressure from 761 women, and blood biomarkers from 450-454 women. We used multivariable regression to evaluate the association of log2-transformed PFAS with postpartum anthropometry, blood pressure, and blood biomarkers (leptin, adiponectin, sex hormone binding globulin [SHBG], hemoglobin A1c [HbA1c], interleukin-6 [IL-6], C-reactive protein [CRP]), adjusting for age, pre-pregnancy BMI, ...
Confinement to the rotational plane is characterized by , cos2Ѳ2D , which is the average value of the cosine of the angle between the probe polarization and the rotational ion velocity vector projected onto the detector screen. By observing how , cos2Ѳ2D , evolves in time after the centrifuge pulse is gone, inferences about the coupling strength of helium to the superrotor can be made. If helium couples strongly to the rotor then , cos2Ѳ2D , is expected to be low and decay quickly. If coupling is weak then , cos2Ѳ2D , is high and lasts for a long time. This is measured for carbon disulfide doped droplets and the evolution of , cos2Ѳ2D , is presented, which is an exciting first step in understanding how the rotation dynamics of a molecule can probe the superfluid behaviour of the nanodroplets.. ...