Luciferase reporter constructs are widely used for analysis of gene regulation when characterizing promoter and enhancer elements. We report that the recently developed codon-modified Renilla luciferase construct included as an internal standard for cotransfection must be used with great caution with respect to the amount of DNA transfected. Also, the dual-luciferase reporter vectors encoding Photinus pyralis firefly or Renilla reniformis luciferase showed a linear increase in dose-response with increasing amounts of transfected DNA, but at higher levels of transfected DNA, a reduction in expressed levels of luciferase activity resulted. In addition, treatment with type I interferon (IFN) was found to significantly reduce levels of P. pyralis firefly and Renilla luciferase activity. In contrast, cells transfected with a green fluorescent protein (GFP) reporter construct showed no significant IFN-associated change. The reduction in luciferase activity resulting from IFN treatment was not due to ...

Interference pigment flakes and foils are provided which have color shifting properties. The pigment flakes can have a symmetrical coating structure on opposing sides of a reflector layer, can have an asymmetrical coating structure with all of the layers on one side of the reflector layer, or can be formed with encapsulating coatings around a core reflector layer. The coating structure of the flakes and foils includes a reflector layer, a dielectric layer on the reflector layer, and a titanium-containing absorber layer on the dielectric layer. The pigment flakes and foils exhibit a discrete color shift so as to have a first color at a first angle of incident light or viewing and a second color different from the first color at a second angle of incident light or viewing. The pigment flakes can be interspersed into liquid media such as paints or inks to produce colorant compositions for subsequent application to objects or papers. The foils can be laminated to various objects or can be formed on a

Despite what you might have seen or not seen, there are actually some fireflies living west of the Rocky Mountains, though they mostly keep to themselves and are rarely spotted by humans. Every once in a while, people spot some. This time, one undergrad who was busy insect hunting in the Los Angeles County hit the jackpot after he discovered a new firefly species.

0030]The inventive solderable contact layer can at the same time serve as a protective layer for the reflector layer of the back electrode layer. In the event that silver, copper or other solderable materials or combinations of materials or alloys are employed for the reflector layer, there can occur during the soldering process a complete mixture (alloying) of the tin-solder with some or all layers of the back electrode layer and even up to the semiconductor. Further, this causes very high energy input into the semiconductor, the subjacent front electrode layer and the substrate. Instead of the tin-solder, other metal layers on the side of the metallic reflector layer facing away from the semiconductor layer can also alloy with the metallic reflector layer. This leads to a multiplicity of faults, such as short circuits, layer delaminations, substrate defects such as cracks, shelling, etc., and thus to an elevated proportion of rejects or modules of reduced quality ...

Semiconductor light emitting devices, such as light emitting diodes, include a substrate, an epitaxial region on the substrate that includes a light emitting region such as a light emitting diode region, and a multilayer conductive stack including a reflector layer, on the epitaxial region. A barrier layer is provided on the reflector layer and extending on a sidewall of the reflector layer. The multilayer conductive stack can also include an ohmic layer between the reflector and the epitaxial region. The barrier layer further extends on a sidewall of the ohmic layer. The barrier layer can also extend onto the epitaxial region outside the multilayer conductive stack. The barrier layer can be fabricated as a series of alternating first and second sublayers.

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6THS-4HWX8NX-C&_user=1495569&_coverDate=02%2F13%2F2006&_rdoc=1&_fmt=high&_orig=search&_sort=d&_docanchor=&view=c&_searchStrId=1402624057&_rerunOrigin=google&_acct=C000053194&_version=1&_urlVersion=0&_userid=1495569&md5=b2ccca6fb4c15f90120534c45c40bc8e Construction of a new firefly bioluminescence system using l-luciferin as substrate ...

Dual luciferase assay - proper controls? - posted in Cell Biology: Hey everyone, I am trying to perform a dual luciferase reporter assay in a cell line with promoters established from another cell line. cDNA and protein of the gene are present in both cell lines. Problem: In the new cell line, the luciferase activity for my promoters of interest is below pGL3, whereas TKpGL3 is as highly active as in the other cell line. Renilla activity was equal in all probes. So I am looking for appr...

Lab Reagents Human IgG antibody Laboratories manufactures the single or dual luciferase assay reagents distributed by Genprice. The Single Or Dual Luciferase Assay reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact luciferase assay. Other Single products are available in stock. Specificity: Single Category: Or Group: Dual Luciferase. Dual Luciferase information ...

The Dual Luciferase Reporter Assay allows for the sequential measurement of the activity of two different luciferases, firefly (FFL) and Renilla (RL), in a single sample. The firefly luciferase luminescence is measured first by addition of the FFL Reagent. Next, the RL Reagent is added to the same well. The RL Reagent simultaneously quenches the firefly luciferase luminescence and initiates the Renilla luciferase reaction. The light production of both reactions can be conveniently measured on a luminometer. This bioluminescent dual reporter gene assay is extremely sensitive and is especially suitable for quantifying dual luciferase expression in recombinant cells or in cell free transcription/translation reactions. Assays can be performed in tubes, cuvettes or multi-well plates. ...

The pGL3 Luciferase Reporter Vectors provide a basis for the quantitative analysis of factors that potentially regulate mammalian gene expression. These factors may be cis-acting, such as promoters and enhancers, or trans-acting, such as various DNA-binding factors. The backbone of the pGL2 Luciferase Reporter Vectors was redesigned for the pGL3 Vectors for increased expression, and contains a modified coding region for firefly (Photinus pyralis) luciferase that has been optimized for monitoring transcriptional activity in transfected eukaryotic cells. The assay of this genetic reporter is rapid, sensitive and quantitative. In addition, the Luciferase Reporter Vectors contain numerous features aiding in the structural characterization of the putative regulatory sequences under investigation.. ...

An assemblage useful for autoradiography comprising, in order, a sample layer containing a radioactively labeled biological sample in contact with a phosphor layer, a film layer and a reflector layer. The phosphor layer is preferably a gadolinium oxysulfide containing layer and the film is preferably a photographic film containing a tabular grain emulsion.

Loureiro, Luiz Victor Maia; Victor, Elivane da Silva; Callegaro-Filho, Donato; Koch, Ludmila de Oliveira; Pontes, Luciola de Barros; Weltman, Eduardo; Rother, Edna Terezinha; Fleury Malheiros, Suzana Maria (Elsevier ireland ltd, 2016) ...

PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.

R&D Systems™ d-Luciferin Recombinant Protein 5mg R&D Systems™ d-Luciferin Recombinant Protein Proteins L

The cheapest D-luciferin potassium salt (luciferin or D-luciferin) for in vivo imaging and in vitro luciferase reporter assays detecting gene expression and detecting the level of cellular ATP in cell viability assays or for kinase activity assays.

The use of sky lanterns during any celebration can turn into tragedy if they land on someones house, over any flammable materials or people, State Fire Marshal Brian S. Geraci said in a release. We must protect the lives and property of the citizens we serve. You could face misdemeanor charges of negligently causing a fire under Health and Safety Code Section 13001. I find your logic to be lacking about Sky Lanterns. Aerial luminaries, commonly referred to as sky lanterns, are prohibited throughout the state, according to the Office of the State Fire Marshal. Sky lanterns, also known as Chinese lanterns, are usually made of oiled rice paper on bamboo frames with a candle or fuel cell inside. Although you are unlikely to face criminal consequences if you use a paper lantern, you could be in serious legal trouble if your sky lantern starts a fire. Anyone over 18 years of age and capable of handling a lighter can responsibly release sky lanterns. There is also concern about the open fire and ...

The firefly fairy (Angelicae lampyridae) collects coins during the day and stores them in a pouch about her waist. She takes great care to polish the coins to a most desirable shininess. At night, when she runs across a firefly trapped inside a jar by an awestruck human, she frees the captive and leaves a quarter in his or her place. Although she develops endurance and strength from carrying coins, the firefly fairy naturally possess incredible energy, most likely to match that of fireflies.. ...

Team:Cambridge/Templates/header}} {{:Team:Cambridge/LumNavTemplate}} ==Photinus Pyralis (Firefly Luciferase)== ==EPIC luciferase== ==Bacterial Bioluminescence== *[[Team:Cambridge/VibrioFischeri, Vibrio Fischeri]] *[[Team:Cambridge/VibrioHarvei, Vibrio Harveyi]] *[[Team:Cambridge/ProjectBioluminescence/Luciferase/WikiGeneticsLuxCDABE, Genetics of luxCDABE (adapted from wikipedia)]] *[http://parts.mit.edu/wiki/index.php/Lux_operon, 2006 attempts at BioBricking the lux operon] *[[Team:Cambridge/ProjectBioluminescence/Luciferase/Notes, Notes]] *[http://partsregistry.org/Lux The lux wiki from parts registry] *[http://departments.kings.edu/biology/lux/bacterial.html Vibrio plasmid experiment] -possible source of lux operon *[http://www.ncbi.nlm.nih.gov/nuccore/AF170104.1?report=graph&log$=seqview NCBI Lux operon sequence] *[http://partsregistry.org/Part:BBa_G10001 parts registry lux operon] -currently waiting on an email to see how useful/available this part is ...

NanoLuc® (Nluc) luciferase is a small enzyme (19.1kDa) engineered for optimal performance as a luminescent reporter. The enzyme is about 100-fold brighter than either firefly (Photinus pyralis) or Renilla reniformis luciferase. Use the pNL3.2.NF-κB-RE[NlucP/NF-κB-RE/Hygro] Vector to assess the cellular response to NF-kappaB.

Richland 12 Round Chinese Paper Lanterns. Our Richland Paper lanterns can instantly transform a room or event space! Mix and match colors and sizes to create the perfect atmosphere. Hang these lanterns high above your guests and fill with string lights to illuminate, hang from trees for an outdoor gathering, or group them above tables, buffets, or even above your desk in your office! So much fun and so many possibilities! Paper Lanterns are a festive and economical way to add color and fun to your home, event, or office. Our lanterns are easy to use and can be folded back flat and re-used time and time again! These lanterns come in 8 and 16 as well. Available in 9 additional colors so you can pick the one just right for you. Simple assembly required.. Colors Available: White, Purple, Turquoise, Green, Red, Orange, Yellow, Silver, Gold, or Fuchsia. Dimensions:12 in Diameter. ...

Shoji Decor specializes in Paper Lanterns that range from Large Paper Lanterns, to Paper Round Lanterns, to Hanging Lanterns with Lights.

Shoji Decor specializes in Paper Lanterns that range from Large Paper Lanterns, to Paper Round Lanterns, to Hanging Lanterns with Lights.

Morbid obesity (MO) is associated with an increase in circulating levels of systemic acute phase proteins such as C-reactive protein (CRP). Toll-like receptor is possible candidate for inflammatory responses which is mainly mediated by NFKB1. The aim of this study was to investigate the relationship between NFKB1 and Toll-like receptor (TLR) 2 polymorphisms and the risk of MO in a Turkish population in the context of CRP serum levels which may contribute to susceptibility to the disease. We analysed the distribution of NFKB1-94 ins/del ATTG rs28362491 and TLR2 Arg753Gln rs5743708 polymorphisms using PCR-RFLP method and CRP serum levels using ELISA method in 213 MO and 200 healthy controls ...

The Green Lantern Movie is getting into the Milk Mustache craze releasing this poster of Ryan Reynolds as The Green Lantern sporting a milk mustache, titled Join the Corps: Green Lantern Lights Up With the Super Powers of Milk.. Green Lantern wants you to know you dont need to have a power ring or lantern to have the strength and lean muscle of a superhero. Along with exercise, the high-quality protein in lowfat milk can help give you extraordinary power to build, maintain and repair your muscles.. ...

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Learn more about D-Luciferin, Free Acid and get the best prices in the life science marketplace at AG Scientific, Inc. We have over 20 years of experience with biochemical supplies that were excited to share with you!

Data Availability StatementThe datasets used during the present study are available from the corresponding author upon reasonable request. negative control using Lipofectamine? 3000 reagent (Invitrogen; Thermo Fisher Scientific, Inc.). After 48 h, cells were lysed and assayed for luciferase activity using a dual luciferase reporter assay (Promega Corporation). Normalized luciferase activity was reported as luciferase activity/luciferase activity. Statistical analysis All data are presented as the mean standard deviation. SPSS 21.0 statistical software (IBM Corp., Armonk, NY, USA) was used to explore the statistical analysis. Comparisons between two groups were conducted using two-tailed Students t-test and multiple group comparisons were conducted via one-way analysis of variance with Tukeys post hoc test. P 0.05 was considered to indicate a statistically significant difference. Results miR-106b-3p is upregulated in ESCC tissues and cell lines The expression of miR-106b-3p in 50 paired ESCC ...

Purpose miR-98, a member of the let-7 family of microRNAs, is downregulated in many malignant tumors and has been correlated with tumor progression. sites using a pGL-3 control vector (Promega Corporation, Fitchburg, WI, USA). The day before transfection, 293T cells were plated onto 24-well dishes (1105 cells/well). Cells were transfected with the PGL-3 luciferase reporter vector, pRL-TK, with or without miR-98 mimics using Lipofectamine? transfection reagent. Luciferase activity was assessed with the Dual Luciferase Reporter Assay System (Promega Corporation). Immunohistochemical staining A total of 43 paraffin-embedded tumor specimens were selected for this study. N-RAS antibody (1:50, Santa Cruz Biotechnology, Dallas, TX, USA) was the main antibody used, and phosphate buffered saline (PBS) was used as a unfavorable control. All immunostained sections were blindly independently evaluated by two pathologists. The intensity of immunostaining (unfavorable =0, light yellow =1, light brown =2, ...

Party String Light Set of 4 round Lanterns with incandescent bulbs. Each set includes 10 mini 4D lanterns, end-to-end plugs (similar to Christmas lights), so multiple strings can be connected together (Recommended up to 3 strings only). Assembly...

Mass Effect: Green Lanterns Light. Chapter 1: Prophecy. In brightest day. In blackest night. No evil shall escape my sight. Let those who worship evils might. Beware my power. Green Lanterns Light. -Green Lantern Corps Oath. VVVVVV. Long ago... before there was order. There was chaos.. The universe was consumed by the forces of evil, corruption and anarchy. These forces grew so powerful that they threatened to tear the very fabric of the universe asunder.. Immortal beings known as the Guardians of the Universe took action and harnessed the emerald energy of willpower to form power rings to act as their instruments of justice and order.. From their world, Oa, in the center of the universe, the Guardians divided the cosmos into 3600 sectors, each of which received a power ring. The ring then chose a champion who was tasked with upholding order and justice throughout the universe.. It is said that those chosen by the rings were beings without fear, and possessed an unbreakable will. The ...

Objective: MicroRNAs played an important role in the ischemia brain injury and repair. However, the key microRNA and its function in the stroke patients remain unclear.. Methods: The blood miRNAs profile was analyzed by quantitative Polymerase Chain Reaction (PCR) methods in ischemic stroke patients in the acute phase (48 hours) and subacute phase (10 days), compared to healthy controls with vascular risk factors. The predicted network of differences in the expression of miRNAs was further explored by Ingenuity Pathway Analysis (IPA). The key miRNA was selected and its function and mechanism were explored in ischemic mice subjected to lentivirus vector mediated overexpression. The predicted target was confirmed by the dual luciferase reporter assay system.. Results: After cerebral ischemia, 24 microRNAs were high or low differently expressed in the peripheral blood of stroke patients. The bioinformatics analysis showed a regulated network of stroke cascade, which was consisted of 10 miRNAs ...

HIV-1 Tat exon 1 and Vpr were amplified from the DNA isolated from blood of HIV infected patients and cloned. Clones were got sequenced and aligned against reference sequences using CLUSTAL W. Sim plot analysis was done for recombinants. Their expression was accessed by transfection of HEK 293T cells with myc fusion clones of variants and western blotting using anti-myc antibody. The variant Tat clones were co-transfected with LTR-luc to investigate their LTR transactivation potential by dual luciferase reporter assay. ...

The purpose of the present study was to investigate the effect of microRNA (miR)‑144‑5p on human umbilical vein endothelial cells (HUVECs) to explore the role of miR‑144‑5p in atherosclerosis. miR‑144‑5p expression was upregulated in HUVECs using miR‑144‑5p mimics. The relative expression level of miR‑144‑5p in HUVECs was detected using reverse transcription‑quantitative PCR (RT‑qPCR). Cell proliferation was detected by performing an MTT assay. Apoptosis was determined via flow cytometry. Cell migration ability was detected by a wound‑healing assay. Cell invasion was determined by a transwell assay. The protein levels of phosphorylated (p)‑PI3K, p‑Akt and endothelial nitric oxide synthase (eNOS) were detected using western blot analysis. The binding sites between miR‑144‑5p and 3‑untranslated region of rapamycin‑insensitive companion of mTOR (RICTOR) mRNA were predicted by TargetScan and confirmed by a dual luciferase reporter assay. The present study ...

Systemic lupus erythematosus (SLE) is an autoimmune disease often used as a model in genomics research. The downregulation of microRNA‑101‑3p (miR‑101‑3p) participates in the progression of SLE, although the underlying mechanisms remain to be elucidated. The present study aimed to evaluate the specific roles of miR‑101‑3p in the SLE inflammatory response and its potential mechanisms. Reverse transcription‑quantitative (RT‑q) PCR was used to profile miR‑101‑3p expression in the peripheral blood mononuclear cells (PBMCs) from 40 female patients with SLE and 20 female healthy volunteers. The interactions between miR‑101‑3p and MAPK1 were identified and evaluated using dual‑luciferase reporter and RNA pull‑down assays. The levels of IL‑10 and IFN‑γ were evaluated by enzyme‑linked immunosorbent assay. The expression of NF‑κB p65 and phosphorylated IκBα were evaluated using western blotting. miR‑101‑3p expression was demonstrated to be downregulated in SLE ...

Our study concluded that there was no relationship between PPARγ Pro12Ala genotype and the risk of ischemic stroke. The same result was found by Zafarmand et al. (12), but the opposite conclusion was made by Lee et al. (13). The data of genetic polymorphism of PPARγ C-2821T in diseases were scarce. This novel genetic variant was first identified in the Pima Indian population from Arizona and was reported to associate with metabolic predictors of type 2 diabetes and obesity (14). In the present study, we found a joint effect of the PPARγ −2821C allele and diabetes on the risk of ischemic stroke. Adjusting for traditional cardiovascular risk factors and pharmacological treatment for diabetes, the risk of ischemic stroke in the −2821C allele carriers with diabetes was 9.7 times greater than that of the homozygous T allele carriers without diabetes. Higher transcriptional activity was found in the −2821T allele than in the −2821C allele by using the Dual Luciferase Reporter Assay in ...

Buttonlites are our LED battery lights for paper lanterns. They have been designed specifically for use in our paper lanterns. Buttonlites give a warm white glow to all lanterns and use a wide disbursement LED light bulb. They come ready to hang on a short white cord with an on/off switch and can be used for 36-48hrs when on continuous use.

Multicolor Mini Lantern String Light, 20 Lanterns, 17 ft, Indoor/Outdoor, Connectable, Plugin, Water-Resistant - Festive for Parties & Patio - KAUF.COM is exciting!

These outdoor post lanterns give your home an aesthetically pleasing and modern look. The unique style make it stand out from the common post lanterns or lights, giving your home an amazing look.

Our convenient Yellow Nylon Lantern Party Packs like this ultimate 20-piece assortment includes a combination of different-sized Chinese Nylon Lanterns perfect for birthday parties, Weddings and baby showers. String these up on Patio String Lights...

Use lanterns to illuminate your home inside and out. Our lanterns come in a range of styles and colours, with designs to cater for both candles and tealights.

Add a stunning display of colour to your wedding day with these delicate and contemporary hanging lanterns.These beautifully yellow paper lanterns make a stylish decorative statement which will look amazing at your wedding or party venue.This pack contains 5 yellow lanterns - 3x large and 2x small.3 x 30cm, 2 x 20.5cm

Firefly luciferin, identical to beetle luciferin, is a popular bioluminescent substrate of luciferase, and enables real-time, noninvasive analysis.

This species can reach a size of more than 20 mm but specimens generally found on seaweeds measure just a few millimeters. The body is narrow, elongated, with a semitransparent and slightly yellowish-green hue. Cerebral ganglia, some reproductive and digestive organs, such as the buccal bulb and the esophagus, can be seen by transparency, for instance, two reddish-brown or brown lines, corresponding to the digestive gland can be seen, one on each side of the back, passing very close to the base of the cerata and reaching almost the end of the queue. The head is very short and with two rounded lobes at its anterior margin. The rhinophores are located well ahead of the body and are auriculate, open at its outer side, semitransparent and decorated with white granulations on the tip, in their middle and between the two insertion points into the head. The tip of the rhinophres shows two lobulations, a longer dorsal one and a ventral somewhat shorter one. The cerata are semitransparent and can be ...

Every spiritual action (maqaamaat) is tributary of repentance, while repentance by itself is tributary of another repentance as long as it is not truly sincere: fear (al-khawf) is tributary of repentance when security and false self-assurance show up; hope (al-rajaa) when affliction and despair come; constance (al-sabr) when fright appears; detachment (ascetism) (al-zuhd) when concupiscent thoughts appear; scruple (al-wara) the moment we are seduced by the search of easy ways (rukhas) or by thoughts of longing (tama), the abandon of self towards God (al-tawakkul) when we are subject to an immoderate anticipation or foresight, imagining to have the free will regarding something or when we worry about ways of surviving; contentment (al-ridaa) and submission (al-tasliim) when there is bitterness and rebellion against the failures of destiny; watchfullness (al-muraaqaba) when we show tactlessness [vis-a-vis of God] (suu al-adab) or when we are filled inside with bad thoughts; self examination ...

The overwhelming glorification includes five components: walking towards Allah, constantly walking towards Him, presence within the heart for Him, glorification of Him, and being overwhelmed by His glorification to be concerned with others. The inciting nearness is the closeness to Allah that incites the servant to have these five components. This closeness makes him glorify Allah in a manner that he pays no attention to himself or others. The closer the servant becomes to Allah, the more he glorifies Him and the less mindful he will be for others. The urging joy is happiness and glorification. It is the delight one finds in this nearness. There is nothing in this world comparable in any way to the joy and happiness of the heart and the delight of the eye with Allah and His closeness. This is one of the states in Paradise ...

Our Hibiscus Lantern String Lights feature a floral print in summer colors. Hibiscus Lantern String Lights have a 120V AC string of 10 steady-burn lights.

Lantern style party lights are a great way to decorate your home. Chain of 70 70 White LEDs which are encased in a lantern style shade. Our led version is great value and has really low running costs combined with long lasting bulbs Theres a long 5

After weeks of reports, HBO Max has officially filled the role of Alan Scott, the original Green Lantern of Earth who came out as gay in the pages of DC Comics, for the upcoming Lantern series from Ar...

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Reproduction brass vent rod for the model 242A, 242B, 242C, 247, 249, and similar style lanterns. Will not fit the Australian made 249 lantern ...

The Penumbra LANTERN Delivery Microcatheter is a low-profile microcatheter. The LANTERN catheter shaft offers advanced trackability with 8 transition zones.

Considered the best lantern of its day, the D-Lite was introduced in 1912. It boasts a fat globe which has larger openings for easier cleaning.

Two metal strap globes nest inside one another in this modern industrial inspired lantern. Aged iron finished straps can be adjusted individually to your desired design. Illuminated within from a 3 light cluster, the sphere glows with sleek salvage appeal.

Let the Warehouse of Tiffany Sunsus Lantern Pendant Light accent your room without being the focal point. This simple yet classic pendant light features...

This collection features blown glass and a rustic mixed metal frame evoking nautical and coastal style. Featuring hanging lights in three sizes, vanity lights and a wall sconce, this collection aligns with the upcoming trend of big impact for small spaces. The pendants and lantern defy the commonly held notion that it takes a prominent chandelier and lots of room to make a statement. These fixtures bring style to small nooks and eat-in kitchens and are equally at home when used in a cluster or grouping in larger spaces.