The roles of different dietary proteins in the aetiology of type 2 diabetes (T2D) remain unclear. We investigated the associations of dietary proteins with the risk of incident T2D in Finnish men from the prospective Kuopio Ischaemic Heart Disease Risk Factor Study. The study included 2332 men aged 42-60 years at the baseline examinations in 1984-1989. Protein intakes were calculated from 4-d dietary records. Incident T2D was determined by self-administered questionnaires, fasting blood glucose measurements, 2-h oral glucose tolerance tests, and with national registers. The multivariable-adjusted risk of T2D on the basis of protein intakes was compared by the Cox proportional hazard ratios (HR). During the mean follow-up of 19·3 years, 432 incident T2D cases were identified. Total, animal, meat or dairy product protein intakes were not associated with risk of T2D when the potential confounders were accounted for. Plant (multivariable-adjusted extreme-quartile HR 0·65; 95 % CI 0·42, 1·00; P ...
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BACKGROUND:. Considerable interest and controversy exist concerning the role of psychosocial factors in the pathogenesis of ischemic heart disease. Studies of the prevalence, incidence, and mortality from ischemic heart disease have implicated socioeconomic status, job strain, Type A behavior, hostility, social support, and other variables.. The study used baseline data previously collected as part of the Kuopio Ischemic Heart Disease Risk Factor Study conducted in eastern Finland by the Research Institute of Public Health and the Research Institute of Exercise Medicine, both in Kuopio, and the Finnish National Public Health Institute in Helsinki. The area of eastern Finland lies within the area of greatest morbidity and mortality from ischemic heart disease in Finland, was part of the reference area for the evaluation of the North Karelia Project, and is part of the World Health Organization MONICA project.. DESIGN NARRATIVE:. The study was longitudinal in design. Physical examinations were ...
The Kuopio ischaemic heart disease risk factor study is a population study designed to investigate risk factors for cardiovascular diseases, atherosclerosis, and related outcomes in men from eastern Finland.18 The baseline examinations were carried out between March 1984 and December 1989. The study sample included 3235 eligible men aged 42, 48, 54, or 60 at the baseline examination; 2682 (82.9%) participated. Men with symptomatic coronary heart disease (n = 92) or ischaemia on maximal exercise testing (n = 359),19 or both (n = 585), were excluded from the current analyses. Of the remaining 1646 men, 1605 had data on plasma ascorbate concentration at baseline.. The examination protocol and measurements have been described.10 11 12 13 Plasma ascorbate concentrations were determined by a chromatographic method in deep frozen samples, which were stabilised in 5% metaphosphoric acid immediately after sampling.20 The coefficient of variation between 12 batches was 7.2%.20. Plasma ascorbate ...
Noncommunicable diseases (NCD), also known as chronic diseases, disease groups such as cardiovascular diseases, cancers, chronic respiratory diseases, diabetes, and age-related cognitive decline. They are the major cause of all deaths globally, increasing rapidly in many middle- and low income countries. They also carry an enormous economic burden worldwide. The Institute of Public Health and Clinical Nutrition at the University of Eastern Finland is internationally well known for its top quality cardiovascular research dating back to 1970s. The world famous North Karelia Project was launched here in 1972. More recently, our flagship international public health research has been the KIHD Study (Kuopio Ischaemic Heart Disease Risk Factor Study), which, despite its name, does not focus only on cardiovascular diseases. With the use of vast KIHD data and linkages to comprehensive national health registries, we are able to examine a wide range of potential risk factors and complex paths of various ...
The sources of these fatty acids are fish and fish oils.. Type 2 diabetes is becoming increasingly widespread throughout the world, including Finland. Overweight is the most significant risk factor, which means that diet and other lifestyle factors play important roles in the development of type 2 diabetes. Earlier research has established that weight management, exercise and high serum linoleic acid concentrations, among other things, are associated with reduced risk of diabetes. However, findings on how fish consumption or long-chain omega-3 fatty acids affect the risk of diabetes have been highly contradictory. A protective link has mainly been observed in Asian populations, whereas a similar link has not been observed in European or US studies - and some studies have even linked a high consumption of fish to increased diabetes risk.. Ongoing at the University of Eastern Finland, the Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD) determined the serum omega-3 fatty acid concentrations ...
We did not find evidence that serum n - 3 PUFA concentration or n - 6/n - 3 ratio would be associated with risk of severe depression in middle-aged Finnish men.
Jari Jolkkonen, ThD, is the Bishop of Kuopio Diocese. His earlier roles include General Secretary of the Episcopal Conference in 2007-2012, Lecturer of Systematic Theology at the University of Joensuu in 2006-2007, Theological Secretary to Bishop Eero Huovinen in the Helsinki Chapter in 2002-2006 and 1997-1998, and Military Chaplain in 1999-2000. Jolkkonen is a docent at the University of Eastern Finland and the University of Helsinki, a member of the Advisory Board of the University of Eastern Finland, and a member of the European Academy of Sciences and Arts.. Jukka Pelkonen, MD, PhD, is Professor of Clinical Microbiology. His earlier positions include the Head of the School of Medicine of the University of Eastern Finland in 2010-2017, and he has served as a Vice Dean at the University of Kuopio in 2003-2005, and as a Dean in 2006-2009. Jukka Pelkonen has administrative experience also from outside the academia, as he has been a board member of the Hospital District of Northern Savo since ...
Finland Women Stats, NationMaster. Retrieved from http://www.nationmaster.com/country-info/profiles/Finland/People/Women. Finland Women Stats, NationMaster. 2000-2002. ,http://www.nationmaster.com/country-info/profiles/Finland/People/Women,.. Finland Women Stats, NationMaster, ,http://www.nationmaster.com/country-info/profiles/Finland/People/Women, [assessed 2000-2002]. Finland Women Stats, NationMaster [Internet]. 2000-2002. Avaliable from: ,http://www.nationmaster.com/country-info/profiles/Finland/People/Women,.. Finland Women Stats, NationMaster. Avaliable at: nationmaster.com. Assessed 2000-2002.. Finland Women Stats, NationMaster, http://www.nationmaster.com/country-info/profiles/Finland/People/Women (assessed 2000-2002). Finland Women Stats, NationMaster, http://www.nationmaster.com/country-info/profiles/Finland/People/Women (last visited 2000-2002). Finland Women Stats, NationMaster, http://www.nationmaster.com/country-info/profiles/Finland/People/Women (as of ...
Finland Deaths Stats, NationMaster. Retrieved from http://www.nationmaster.com/country-info/profiles/Finland/Health/Deaths. Finland Deaths Stats, NationMaster. 1948-2012. ,http://www.nationmaster.com/country-info/profiles/Finland/Health/Deaths,.. Finland Deaths Stats, NationMaster, ,http://www.nationmaster.com/country-info/profiles/Finland/Health/Deaths, [assessed 1948-2012]. Finland Deaths Stats, NationMaster [Internet]. 1948-2012. Avaliable from: ,http://www.nationmaster.com/country-info/profiles/Finland/Health/Deaths,.. Finland Deaths Stats, NationMaster. Avaliable at: nationmaster.com. Assessed 1948-2012.. Finland Deaths Stats, NationMaster, http://www.nationmaster.com/country-info/profiles/Finland/Health/Deaths (assessed 1948-2012). Finland Deaths Stats, NationMaster, http://www.nationmaster.com/country-info/profiles/Finland/Health/Deaths (last visited 1948-2012). Finland Deaths Stats, NationMaster, http://www.nationmaster.com/country-info/profiles/Finland/Health/Deaths (as ...
TY - JOUR. T1 - Telomere length and physical performance among older people - the Helsinki Birth Cohort Study. AU - Åström, Max J.. AU - von Bonsdorff, Mikaela B.. AU - Perälä, Mia-Maria. AU - Salonen, Minna K.. AU - Rantanen, Taina. AU - Kajantie, Eero. AU - Simonen, Mika. AU - Pohjolainen, Pertti. AU - Haapanen, Markus J.. AU - Guzzardi, Maria A.. AU - Iozzo, Patricia. AU - Kautiainen, Hannu. AU - Eriksson, Johan G.. PY - 2019/10. Y1 - 2019/10. KW - 3142 Public health care science, environmental and occupational health. KW - Biomarkers. KW - Physical function. KW - Aging. KW - Epidemiology. KW - Biomarkers. KW - Physical function. KW - Aging. KW - Epidemiology. KW - MORTALITY. KW - ASSOCIATION. KW - FRAILTY. KW - BIOMARKERS. KW - DISABILITY. KW - CAPABILITY. KW - FITNESS. KW - MARKERS. KW - HEALTH. KW - BLOOD. U2 - 10.1016/j.mad.2019.111145. DO - 10.1016/j.mad.2019.111145. M3 - Article. VL - 183. JO - Mechanisms of Ageing and Development. JF - Mechanisms of Ageing and Development. SN - ...
From the Institute for Molecular Medicine Finland, FIMM, University of Helsinki, Finland (P-P.L., I.S., A-P.S., J.K., A.P., S.R.); Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland (P-P.L., I.S., A-P.S., J.N., J.K., J.S., C.E., M.J., S.R.); Department of Medical Genetics, University of Helsinki, Helsinki, Finland (P-P.L., A.P.); VTT Technical Research Centre of Finland, Espoo, FIN-02044 VTT, Finland (L.Y., T.H., J.T., M.O.); Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland (S.S., M-R.T.); Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, United Kingdom (M-R.J.); Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland (O.T.R.); Clinical Physiology, University of Turku, and Turku University Hospital, Turku, Finland (O.T.R.); Unit of Chronic Disease Epidemiology and Prevention, National Institute for Health and Welfare, Helsinki, ...
We ascertained incident cases of diabetes from the National Hospital Discharge Register and the National Social Insurance Institutions Drug Register (17, 18, 23, 24, 25). These register data were linked to the risk factor survey data with the unique personal identification numbers assigned to every resident of Finland. Antidiabetic drugs prescribed by a physician are free of charge in Finland, subject to approval of the application to the Social Insurance Institution with a case history prepared by the treating physician attached. The diagnosis of diabetes is confirmed on the basis of the World Health Organization criteria: one or more classical symptom plus a fasting plasma glucose level of 7.0 mmol/liter or more, or the oral glucose tolerance test of 11.1 mmol/liter or more; at least one increased plasma glucose concentration and a fasting plasma glucose level of 7.0 mmol/liter or more, or the oral glucose tolerance test of 11.1 mmol/liter or more in the absence of symptoms; or treatment with ...
The Haveri Au-Cu deposit is located in southern Finland about 175 km north of Helsinki. It occurs on the northern edge of the continental island arc-type, volcano-sedimentary Tampere Schist Belt (TSB) within the Palaeoproterozoic Svecofennian Domain (2.0 - 1.75 Ga) of the Fennoscandian Shield. The 1.99 Ga Haveri Formation forms the base of the supracrustal stratigraphy consisting of metavolcanic pillow lavas and breccias passing upwards into intercalated metatuffs and metatuffites. There is a continuous gradation upwards from the predominantly volcaniclastic Haveri Formation into the overlying epiclastic meta-greywackes of the Osara Formation. The Haveri deposit is hosted in this contact zone. This supracrustal sequence has been intruded concordantly by quartz-feldspar porphyries.. Approximately 1.89 Ga ago, high crustal heat flow led to the generation and emplacement of voluminous synkinematic, I-type, magnetite-series granitoids of the Central Finland Granitoid Complex (CFGC), resulting in ...
Northern Finland Cohorts comprise collections of data and biological samples from large population studies that are administrated by the Northern Finland Birth Cohorts Project Center at the Medical
This study is the first to analyze a comprehensive range of maternal, birth, and childhood measures in relation to adult BP from a large well-characterized general population-based cohort studied since early pregnancy. Our main findings were that (1) the association between birth weight and SBP was inverse-linear, particularly for males, with or without adjustment for current BMI; (2) the association for DBP was inverse but weaker than for SBP; (3) other birth variables (gestational age, birth length, ponderal index, BW-GA) showed a similar pattern with BP, although less consistent than birth weight; (4) among females, the inverse association between gestational age and BP was stronger than that for birth weight; (5) infant change-up growth associated positively with BP; and (6) association of some early life factors (gestational age, ponderal index) with BP seems to be stronger in leaner adults.. A meta-analysis by Huxley et al22 of 82 studies with data on birth weight and BP concluded that ...
The adolescents with ADHD symptoms considered their psychosocial well-being to be poorer than those without ADHD symptoms. In clinical work, it is essential to recognize the most impaired adolescents who need special attention and support at school as well as in their social interactions with their …
COVID-19 Hospital Needs and Death Projections: IHME is producing and regularly updating projections of hospital bed use, need for intensive care beds, ventilator use, and deaths due to COVID-19 based on projected deaths for all 50 U.S. states. Access current projections.. ...
From the Pharmacoeconomics and Outcomes Research Unit (PHORU), School of Pharmacy, University of Eastern Finland, Kuopio; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki; Unit of Primary Health Care, Turku University Hospital, Turku; Department of Internal Medicine, Centre for Rheumatic Diseases, Tampere University Hospital; School of Medicine, University of Tampere, Tampere; South-Karelia Central Hospital, Lappeenranta, Finland. Supported by a grant from the Yrjö Jahnsson Foundation (grant number 6575). J.A. Martikainen, PhD, Associate Professor, PHORU, School of Pharmacy, University of Eastern Finland; H. Kautiainen, BSc, Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, and Unit of Primary Health Care, Turku University Hospital; V. Rantalaiho, MD, PhD, Department of Internal Medicine, Centre for Rheumatic Diseases, Tampere University Hospital, and School of ...
TY - JOUR. T1 - The metabolome in finnish carriers of the MYBPC3-Q1061X mutation for hypertrophic cardiomyopathy. AU - Jørgenrud, Benedicte. AU - Jalanko, Mikko. AU - Heliö, Tiina. AU - Jääskeläinen, Pertti. AU - Laine, Mika. AU - Hilvo, Mika. AU - Nieminen, Markku S.. AU - Laakso, Markku. AU - Hyötyläinen, Tuulia. AU - Oresic, Matej. AU - Kuusisto, Johanna. N1 - CO:U Hormone Laboratory, Aker Hospital, Oslo University Hospital, Oslo, Norway CO:U Division of Women and Childrens Health, Department of Pediatric Research, Oslo University Hospital, Oslo, Norway CO:K Helsinki University Central Hospital, Department of Cardiology, Helsinki, Finland CO:K Kuopio University Hospital, Heart Center, Kuopio, Finland CO:K University of Eastern Finland, Kuopio University Hospital, Department of Medicine, Kuopio, Finland CO:U Steno Diabetes Center, Gentofte, Denmark CA2: BA3112 CA2: BA116 AU2: Hilvo, Mika AU2: Hyötyläinen, Tuulia AU2: Oresic, Matej ISI: MULTIDISCIPLINARY SCIENCES. PY - 2015. Y1 - ...
Find the best around Helsinki,SOUTHERN FINLAND and get detailed driving directions with road conditions, live traffic updates, and reviews of local business along the way.
Medaffcon has in collaboration with the University of Eastern Finland assessed the operational status of the Finnish hospital biobanks.
In 2010, Finlands greenhouse gas emissions amounted to 74.6 million tonnes of carbon dioxide (CO2 eq.). They rose by a total of 8.5 million carbon dioxide tonnes from the year before, exceeding the commitment level of the Kyoto Protocol by around five per cent. The data are based on the preliminary estimate to be submitted by Statistics Finland to the European Commission on 15 January 2012 concerning emissions in 2010.. In the energy sector, emissions increased by 15 per cent from the previous year. Emissions from industrial processes rose by eight per cent. Emissions from agriculture and use of solvents and other products also increased slightly. Emissions in the waste sector remained unchanged. Net sinks in the Land use, Land-use Change and Forestry sector (LULUCF) dropped by 40 per cent mainly because of increased fellings.. Development of greenhouse gas emissions by sector in Finland 1990-2010. ...
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TY - THES. T1 - Aging, cognitive ability and the risk of dementia in the Helsinki Birth Cohort Study. AU - Rantalainen, Ville. PY - 2019/3/22. Y1 - 2019/3/22. KW - 515 Psychology. M3 - Doctoral Thesis. SN - 978-951-51-4797-4. PB - University of Helsinki. CY - Helsinki. ER - ...
BACKGROUND: Early life risk factors are associated with cardiometabolic disease, but have not been fully studied in atrial fibrillation (AF). There are discordant results from existing studies of birth weight and AF, and the impact of maternal body size, gestational age, placental size, and birth length is unknown.. METHODS AND RESULTS: The Helsinki Birth Cohort Study includes 13 345 people born as singletons in Helsinki in the years 1934-1944. Follow-up was through national registries, and ended on December 31, 2013, with 907 incident cases. Cox regression analyses stratified on year of birth were constructed for perinatal variables and incident AF, adjusting for offspring sex, gestational age, and socioeconomic status at birth. There was a significant U-shaped association between birth weight and AF (P for quadratic term=0.01). The lowest risk of AF was found among those with a birth weight of 3.4 kg (3.8 kg for women [85th percentile] and 3.0 kg for men [17th percentile]). High maternal body ...
The 20th Voorburg Group Meeting on Service Statistics will be held in Helsinki, Finland. The meeting will be hosted by Statistics Finland from Monday 26th September to Friday 30th September 2005. The main topics to be discussed will be producer prices indexes in services, measurement of turnover of services and classifications of service activities and products. The meeting language will be English.. ...
According to Statistics Finland, a total of 21,900 polytechnic degrees were attained in Finland in 2010. This is 4 per cent more than in the year before. The numbers of degrees were highest in the fields of welfare, health and physical exercise as well as in technology and transport. The proportion of women of polytechnic degrees was 63 per cent. Higher polytechnic degrees were obtained by 1,253 students, of whom 64 per cent were women.. Polytechnic degrees by region 2010. ...
16:36 527. Determination of Cerebral Blood Volume and Mean Transit Time by Dynamic Contrast Enhanced MR Imaging in Patients with Acute Stroke: A Comparison of Four Post Processing Methods, J. Perki , H.J. Aronen, J. Karonen, Y. Liu, S. Savolainen and L. stergaard, Kuopio University Hospital, Kuopio, Finland; Helsinki University Central Hospital, Helsinki, Finland; University of Helsinki, Helsinki, Finland and Aarhus University Hospital, Aarhus, Denmark. ...
ISSN=2342-6721. 2003, Public sector R&D expenditure by sector in 2000-2003 . Helsinki: Statistics Finland [referred: 20.9.2020 ...
The birth records at Helsinki University Central Hospital contain data on the mothers as well as their newborn babies. Data on the mothers include age, parity, height, and date of the last menstrual period, together with body weight measured on admission in labour. Height was recorded to the nearest 0.5 cm and weight to the nearest 0.5 kg. Data on the newborn babies include birth weight, placental weight, length, and head circumference. Birth weight and placental weight were rounded to the nearest 5 g and length and head circumference to the nearest 0.5 cm. Birth weight was recorded for all 2785 term babies, born after 37 completed weeks of gestation, on which most of our analyses are based. Placental weight was recorded for 2784, length for 2772, head circumference for 2781, mothers height for 2626, and mothers weight for 2610.. We studied a sample of men who were born at the hospital between 1924 and 1933, went to school in the city of Helsinki, and were still resident in Finland in 1971. ...
Juha Heiskala,1 Tuomas Neuvonen,1 P. Ellen Grant,2 and Ilkka Nissilä3 1J. Heiskala ([email protected]) is with the BioMag Laboratory and T. Neuvonen is with the Department of Clinical Neurophysiology, Helsinki University Central Hospital, P.O. Box 340, HUS, FIN-00029, Helsinki, Finland. J. Heiskala and T. Neuvonen are also with the Helsinki Brain Research Center, University of Helsinki, P.O. Box 13, FIN-00014, Helsinki, Finland. J. Heiskala is also with the Laboratory of Biomedical Engineering, Helsinki University of Technology, P.O. Box 2200, FIN-02015 HUT, Finland. T. Neuvonen is also with the Department of Physiology, Neuroscience Unit, Institute of Biomedicine, University of Helsinki, P.O. Box 63, FIN-00014, Helsinki, Finland. 2P. E. Grant is with the Department of Pediatric Radiology, Massachusetts General Hospital, Boston, Massachusetts 02114. 3I. Nissilä, as well as P. E. Grant, is with the Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 149 13th ...
Remember the joy swell up inside when you simply went to the ice cream shop for your favorite cone on a hot sunny day? Isnt it funny how you suddenly feel at peace when you sit back and let pure milk chocolate slowly melt on your tongue?. It may sound silly, but junk food could actually be contributing to your bad moods and even be a factor in depression. Yep, even though it makes you feel so good right then, while youre in the moment, you might wanna consider not enjoying that sweet next time.. There have been multiple studies conducted that cited there are links between eating junk food and depression. And the evidence just seems to be adding up. Researchers are actively trying to pinpoint exactly how and why it happens, but heres what we already know…. Anu Ruusunen, from the University of Eastern Finland, brought forward her analysis on the Kuipio Ischaemic Heart Disease Risk Factor Study. She believes that the participants in this population based study who strived to eat plenty of ...
Maternal schizophrenia and out-of-home placements of offspring: A national follow-up study among Finnish women born 1965-1980 and their ...
Mikhail SALTYCHEV 1 ✉, Katri LAIMI 1, Juho RANTAKOKKO 2, Ryan MATTIE 3, Zachary MCCORMICK 4, Ville AALTO 5, Mika KIVIMÄKI 6, 7, Jussi VAHTERA 8. 1 Department of Physical and Rehabilitation Medicine, Turku University Hospital, University of Turku, Turku, Finland; 2 Department of Orthopedics, Turku University Hospital, University of Turku, Turku, Finland; 3 Department of Orthopedic Surgery, Physical Medicine and Rehabilitation, Stanford University Hospital and Clinics, Palo Alto, CA, USA; 4 Department of Orthopedic Surgery, Physical Medicine, and Rehabilitation, University of California, San Francisco, CA, USA; 5 Finnish Institute of Occupational Health, Turku and Helsinki, Finland; 6 Clinicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland; 7 Department of Epidemiology and Public Health, University College London Medical School, London, UK; 8 Department of Public Health, University of Turku, Turku University Hospital, Turku, Finland. ...
Purpose The aim of the study was to investigate sickness absence due to mental disorders in human service occupations. Methods Participants (n = 1,466,100) were randomly selected from two consecutive national 9-year cohorts from the Statistics Finland population database; each cohort represented a 33% sample of the Finnish population aged 25-54 years. These data were linked to diagnosis-specific records on receipt of sickness allowance, drawn from a national register maintained by the Social Insurance Institution of Finland, using personal identification numbers. Results Sociodemographic-adjusted hazard ratios (HRs) for sickness absence due to mental disorders in all human service occupations combined were 1.76 for men (95% confidence interval [CI], 1.70-1.84) and 1.36 for women (95% CI, 1.34-1.38) compared with men and women in all other occupations, respectively. Of the 15 specific human service occupations, compared with occupations from the same skill/education level without a significant
The same timeframes apply concerning access to treatment for mental health disorders for adults (over 23 years) as with other medical services.. The treatment evaluations and specialist assessments of children and young people (under 23 years) must be carried out within six weeks referral. Treatment must be provided within three months of its prescription.. Child welfare clinics and school and student health services play an important role in the prevention, detection and provision of support concerning mental health problems in children and young people. Occupational health supports mental health and problem prevention among the working population.. The Social Insurance Institution reimburses rehabilitative psychotherapy for work or school performance improvement for persons between 16-67 years of age.. The Social Insurance Institution (Kela) reimburses the costs of rehabilitative psychotherapy to improve the capacity to work or study for people aged between 16-67.. ...
Cubilin is a 460-kd multiligand hydrophobic protein that binds to intrinsic factor cobalamin (Cbl-IF) with a high affinity and that is expressed in both kidney and ileal epithelial cells. Based on this observation, it has been speculated that cubilin and intrinsic factor cobalamin receptor (IFCR) are identical.1Recently, Kristiansen et al showed that the P1297L mutation of cubilin (FM1) associated with selective congenital cobalamin malabsorption (Imerslund-Gräsbeck disease, described in Finnish patients; also named megaloblastic anemia 1 [MGA1]) causes a 5-fold decrease of the binding domain affinity for Cbl-IF.2 They concluded that this decreased affinity explained the malabsorption of Cbl and the Cbl deficiency related to the FM1 mutation of MGA1 patients. In our opinion, the pathogenetic mechanism suggested by Kristiansen et al does not explain the whole biologic phenotype of the Finnish patients. The P1297L mutation of cubilin has been found in 16 of 17 Finnish patients but not in ...
CONTEXT: Impaired fetal growth is associated with increased risk for coronary heart disease and diabetes in adulthood, but the underlying mechanism is unclear. OBJECTIVE: The objective of the study was to examine the relation between early growth (weight at birth and first year) and adult total leukocyte count, the primary cell effectors of inflammation. DESIGN: This was a birth cohort study (Northern Finland Birth Cohort 1966) with participants prospectively and longitudinally followed up from birth to age 31 yr. SETTING: This was a general population-based cohort in Finland. PARTICIPANTS: A total of 5619 offspring of expectant mothers who attended a clinical examination and blood draw at 31-yr follow-up (4486 with complete data on weight at 1 yr) participated in the study. MAIN EXPOSURE VARIABLES: Weight at birth and at 1 year. MAIN OUTCOME MEASURE: Absolute leukocyte count was measured. RESULTS: Total leukocyte count was lower at higher birth weight categories with or without adjustments for adult
Clinical findings in 21 Finnish children with congenital chloride diarrhoea are reported. Inheritance of this disease by the autosomal recessive mode is established. All children were born 1-8 weeks prematurely. Hydramnios was present in every case and no meconium was observed; intrauterine onset of diarrhoea is thus apparent. In most cases the diarrhoea or passing of large volumes of urine was noted on the first day of life and the abdomen was usually large and distended. The neonatla weight loss was abnormally large, and was associated with hypochloraemia and hyponatraemia. Some infants survived the neonatal period without adequate therapy. They presented later with failure to thrive and usually had hypochloraemia, hypokalaemia, and metabolic alkalosis associated with hyperaldosteronism. However, these features may be absent and the diagnosis is based on a history of hydramnios and diarrhoea, and a faecal Cl- concentration which always exceeds 90 mmol/l when fluid and electrolyte deficits ...
Watch The Video: Microneurosurgical Clipping Of An Unruptured Intracranial Aneurysm ]. University of Helsinki The lifetime risk for rupture of a brain aneurysm depends heavily on the patients overall load of risk factors. However, a recent study by researchers from the University of Helsinki and Helsinki University Central Hospital demonstrated that the size of an aneurysm has no great significance on the risk of rupture.. This is a unique study in that it monitored aneurysm patients over their entire lifetimes, whereas typical follow-up studies last only between one and five years in duration. The study is also exceptionally broad in scope; Dr. Seppo Juvela points out that the only other place where a study of similar scope has been conducted is Japan.. It is unlikely that another similar, non-selected lifetime follow-up study on aneurysm patients will ever be conducted again, he states.. Current care practices are based largely on the results of previous, shorter studies. Such studies have ...
Purpose. We compared the quality and pattern of use of antibiotics to treat urinary tract infection (UTI) between institutionalized and home-dwelling elderly.. Methods. We analyzed the quality of use of UTI antibiotics in Swedish people aged ≥65 years at 30 September 2008 (1,260,843 home-dwelling and 86,721 institutionalized elderly). Data regarding drug use, age and sex were retrieved from the Swedish Prescribed Drug Register and information about type of housing from the Social Services Register. In women, we assessed: (1) the proportion who use quinolones (should be as low as possible); (2) the proportion treated with the recommended drugs (pivmecillinam, nitrofurantoin, or trimethoprim) (proportions should be about 40 %, 40 % and 15-20 %, respectively); In men, we assessed: (1) the proportion who used quinolones or trimethoprim (should be as high as possible).. Results. The 1-day point prevalence for antibiotic use for UTI was 1.6 % among institutionalized and 0.9 % among home-dwelling ...
Host institute: Helsinki University Central Hospital. My three months glaucoma fellowship was preceded by attending the 7th World Glaucoma Congress which was held from June 28- July 1 in Helsinki. This was perhaps the most ideal way to start the fellowship as I was able to meet some of the doctors that I would be working with, and it set a great academic tone to the rest of my fellowship. The congress itself was phenomenal and very well organized, and included great wet labs as well as a wide variety of current glaucoma related topics.. I had the privilege of working with a friendly and highly experienced team under the great leadership of Dr Paivi Puska (Glaucoma departmental Head). I was able to attend both the outpatient clinics as well as the theatres. Clinic work included various laser treatments such as SLT, Argon, Yag and diode lasers. I learnt a wide variety of surgical procedures and techniques, and these included amongst others deep sclerectomy, trabeculectomy with mmc, MIGS ...
Terkko Navigator is a medical library community for the University of Helsinki and Helsinki University Central Hospital. Personalize your own library of feeds, journals, books, links and more ⇒ ⇒
Terkko Navigator is a medical library community for the University of Helsinki and Helsinki University Central Hospital. Personalize your own library of feeds, journals, books, links and more ⇒ ⇒
This post is also available in: Finnish, Swedish. Trade unions for the Federation of Salaried Employees (Pardia), the Trade Union for the Public and Welfare Sectors (JHL) and the Public Sector Negotiating Commission (JUKO) have submitted notice on a spot strike to be held at the University of Helsinki. The strike will take effect on 28 February at midnight, ending 24 hours later. The objective of the strike is to put pressure on the employer in the negotiations on renewing the terms of the general collective agreement for universities.. As the Helsinki University Library is part of the University of Helsinki, the strike will affect its operations.. On the strike day, 28 February 2018, most Helsinki University Library facilities will be closed. Neither can the library guarantee uninterrupted service by phone or online.. The Helsinki University Library at Kaisa House, the Kumpula Campus Library and the Viikki Campus Library will be closed entirely.. On the strike day, the Learning Centres ...
The diagnoses of liver and biliary disease were traced from the Finnish Hospital Discharge Register with an almost 100% coverage. The researchers found that patients with intrahepatic cholestasis of pregnancy had a higher incidence of liver and biliary disease than in controls. The rate ratio for Hepatitis C was 4, for nonalcoholic liver cirrhosis 8.. The team noted that the rate ratio for gallstones and cholecystitis was 4, and 3 for nonalcoholic pancreatitis. Dr Ropponens team concluded, There is an association of intrahepatic cholestasis of pregnancy with several liver and biliary diseases. Some patients with Intrahepatic cholestasis of pregnancy are at risk of the subsequent development of cirrhosis and other severe chronic diseases. Contrary to what has been previously thought, follow-up may need to be considered for these patients. ...
A suspected assailant has been shot in the leg and detained after a stabbing incident in Turku, south-west Finland. At least one person was seen lying on the ground and others were reported to be hurt on Friday afternoon. Police say that several people have been stabbed and ask the public to avoid the area.. A knife-wielding man attacked eight people in downtown Turku on Friday afternoon, killing two and wounding at least six.. At a press conference on Friday evening, police said that eight people were stabbed in the incident, which began at 16:02, and two of them had died. The suspect was shot in the leg and apprehended by police by 16:05, and as of Friday evening was being treated in hospital.. The hospital director director said on Friday evening that all of the victims were adults.. Police said that the incident was not being investigated as a terror attack, but that could change as new information comes to light. The National Bureau of Investigation had taken over the probe from the Turku ...
Finland was a province and then a grand duchy under Sweden from the 12th to the 19th centuries, and an autonomous grand duchy of Russia after 1809. It gained complete independence in 1917. During World War II, Finland successfully defended its independence through cooperation with Germany and resisted subsequent invasions by the Soviet Union - albeit with some loss of territory. In the subsequent half century, Finland transformed from a farm/forest economy to a diversified modern industrial economy; per capita income is among the highest in Western Europe. A member of the EU since 1995, Finland was the only Nordic state to join the euro single currency at its initiation in January 1999. In the 21st century, the key features of Finlands modern welfare state are high quality education, promotion of equality, and a national social welfare system - currently challenged by an aging population and the fluctuations of an export-driven economy ...
Kofi Amegah (left), who is finishing a doctoral dissertation at the University of Oulu, investigated the effects of domestic heating and cooking emissions on foetal weight in Ghana. Also in the picture are Professor Jouni Jaakkola from the University of Oulu Centre for Environmental and Respiratory Health Research (CERH) and Ghanaian researcher Reginald Quansah.. Finland is not an island. Although climate change will have the severest effects on developing countries, Finland will not be immune to its health impacts. In a century or so, almost all of Finland will form part of a different climate zone to now.. In a developed country like Finland, we can prepare for a number of threats, such as a higher frequency of storms and floods. But surprises are also bound to occur, Jaakkola predicts.. Precipitation is forecast to increase, particularly in winter. Temperatures fluctuating above and below zero will increase the slipperiness of roads and the number of accidents.. Cold periods are likely to ...
The author of the study that claims that daylight saving time affects us more than we thought, Jori Ruuskanen, from Finlands Turku University, declared that the risk of having an ischemic stroke is raised by the bi-annual clock change.. Dr. Ruuskanen discovered that the internal clock of the body, or the circadian rhythm, is significantly disrupted by daylight saving time, thus increasing the risk of an ischemic stroke. This type of condition is actually very common.. Usually, it is caused by a blood clot that plugs or blocks a blood vessel in the brain. The block stops the blood from traveling to the vital organ, and so brain cells begin to die rapidly. The Heart Association of America stated that ischemic strokes account for approximately 87 percent out of the total number of strokes.. In order to reach his conclusions, Dr. Ruuskanens team analyzed stroke data from Finlands hospitals from 2004 until 2013. The researchers compared the stroke rate in roughly 3,000 people that were ...
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Philip R. Valera, 50, a Redondo Beach resident who headed the South Bay Alcoholism Council for six years during the 1970s, has been named chief executive officer of the South Bay Hospital District,
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Finland including Karelia and Estonia was the eastern part of The Kingdom of Sweden from its unification around 1100 - 1200 AD until the year 1809 when Finland was conquered by Russia. During the Russian revolution 1917, Finland proclaimed the republic Finland and Sweden and many European countries rapidly acknowledged the new nation Finland. Finland has mainly Finnish (increasing) and Swedish (decreasing) surnames and first names. There are two predominant surname traditions among the Finnish in Finland: the West Finnish and the East Finnish. The surname traditions of Swedish-speaking farmers, fishermen and craftsmen resembles the West Finnish tradition, while smaller populations of Sami and Romani people have traditions of their own. Finland was exposed to a very small immigration from Russia, so Russian names barely exists. Until the mid 20th Century, Finland was a predominantly agrarian society, and the names of West Finns were based on their association with a particular area, farm, or ...
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The endogenous insulin secretion capacity of 171 insulin-treated middle-aged persons with diabetes (81 men, 90 women) of the Kuopio University Central Hospital district (population 250,000), East Finland, was measured by the C-peptide response to glucagori. The prevalence of insulin deficiency among initially non-insulin-dependent diabetic (NIDDM) individuals was calculated on the basis of those who were initially treated with diet or oral drugs and 3 yr or more after diagnosis had been treated with insulin and were insulin deficient in this study. The prevalence of complete insulin deficiency (postglucagon C-peptide undetectable) was among initially NIDDM individuals of the same region, 0.7% in menand 1.2% in women. Using the postglucagon C-peptide level of 0.20 nmol/L as a cut-offpoint, the prevalence of insulin deficiency was 2.0% in men and 1.9% in women and, on thebasis of C-peptide level of 0.60 nmol/L, the prevalence of insulin deficiency was 3.5% in men and 2.7% in women. Our data ...
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The mechanism behind the lowered postprandial insulin demand observed after rye bread intake compared to wheat bread is unknown. The aim of this study was to use the metabolomics approach to identify potential metabolites related to amino acid metabolism involved in this mechanism. A sourdough fermented endosperm rye bread (RB) and a standard white wheat bread (WB) as a reference were served in random order to 16 healthy subjects. Test bread portions contained 50 g available carbohydrate. In vitro hydrolysis of starch and protein were performed for both test breads. Blood samples for measuring glucose and insulin concentrations were drawn over 4 h and gastric emptying rate (GER) was measured. Changes in the plasma metabolome were investigated by applying a comprehensive two-dimensional gas chromatography coupled to time-of-flight mass spectrometry metabolomics platform (GC×GC-TOF-MS). Plasma insulin response to RB was lower than to WB at 30 min (P = 0.004), 45 min (P = 0.002) and 60 min (P | 0.001)
The aim of this study was to assess the excess risk attributable to alterable risk factors for acute otitis media in Finnish children, including day care attendance, parental smoking, and a short duration of breastfeeding. Data on a population-based cohort of 2,512 children were gathered from medical records and questionnaires from 1985 to 1988....