J:173650 Sgantzis N, Yiakouvaki A, Remboutsika E, Kontoyiannis DL, HuR controls lung branching morphogenesis and mesenchymal FGF networks. Dev Biol. 2011 Jun 15;354(2):267-79 ...
Expression of human keratinocyte growth factor (KGF/FGF-7) was directed to epithelial cells of the developing embryonic lung of transgenic mice disrupting normal pulmonary morphogenesis during the pseudoglandular stage of development. By embryonic day 15.5(E15.5), lungs of transgenic surfactant protein C (SP-C)-KGF mice resembled those of humans with pulmonary cystadenoma. Lungs were cystic, filling the thoracic cavity, and were composed of numerous dilated saccules lined with glycogen-containing columnar epithelial cells. The normal distribution of SP-C proprotein in the distal regions of respiratory tubules was disrupted. Columnar epithelial cells lining the papillary structures stained variably and weakly for this distal respiratory cell marker. Mesenchymal components were preserved in the transgenic mouse lungs, yet the architectural relationship of the epithelium to the mesenchyme was altered. SP-C-KGF transgenic mice failed to survive gestation to term, dying before E17.5. Culturing mouse ...
The keratinocyte growth factor (KGF), also known as FGF7, is a growth factor present in the epithelialization-phase of wound healing. In this phase, keratinocytes are covering the wound, forming the epithelium. KGF is a small signaling molecule that binds to fibroblast growth factor receptor 2b (FGFR2b).[1] For signalling to occur, a dimer is required between two FGF:FGFR complexes that is linked together by a molecule of heparin. There are 23 known FGFs, and 4 FGF receptors. FGF:FGFR binding is complex and regulated by a variety of mechanisms in a tissue specific manner. FGF10 is also known as keratinocyte growth factor 2.[2] ...
TY - JOUR. T1 - Liposomal Gene Transfer of Keratinocyte Growth Factor Improves Wound Healing by Altering Growth Factor and Collagen Expression. AU - Pereira, Clifford. AU - Herndon, David N.. AU - Rocker, Roland. AU - Jeschke, Marc G.. PY - 2007/5/15. Y1 - 2007/5/15. N2 - Background: Growth factors affect the complex cascade of wound healing; however, interaction between different growth factors during dermal and epidermal regeneration are still not entirely defined. In the present study, we thought to determine the interaction between keratinocyte growth factor (KGF) administered as liposomal cDNA with other dermal and epidermal growth factors and collagen synthesis in an acute wound. Materials and methods: Rats received an acute wound and were divided into two groups to receive weekly subcutaneous injections of liposomes plus the Lac-Z gene (0.22 μg, vehicle), or liposomes plus the KGF cDNA (2.2 μg) and Lac-Z gene (0.22 μg). Histological and immunohistochemical techniques were used to ...
TY - JOUR. T1 - Short-term inhibition of p53 combined with keratinocyte growth factor improves thymic epithelial cell recovery and enhances T-cell reconstitution after murine bone marrow transplantation. AU - Kelly, Ryan M.. AU - Goren, Emily M.. AU - Taylor, Patricia A.. AU - Mueller, Scott N.. AU - Stefanski, Heather E.. AU - Osborn, Mark J.. AU - Scott, Hamish S.. AU - Komarova, Elena A.. AU - Gudkov, Andrei V.. AU - Holländer, Georg A.. AU - Blazar, Bruce R.. PY - 2010/2/4. Y1 - 2010/2/4. N2 - Myeloablative conditioning before bone marrow transplantation (BMT) results in thymic epithelial cell (TEC) injury, T-cell immune deficiency, and susceptibility to opportunistic infections. Conditioning regimen-induced TEC damage directly contributes to slow thymopoietic recovery after BMT. Keratinocyte growth factor (KGF) is a TEC mitogen that stimulates proliferation and, when given before conditioning, reduces TEC injury. Some TEC subsets are refractory to KGF and functional T-cell responses are ...
Effects of Keratinocyte Growth Factor on the Uterine Endometrial Epithelial Cells in Pigs - Keratinocyte Growth Factor;Porcine;Uterus;Endometrium;Epithelia;
We investigated the expression and distribution of keratinocyte growth factor (KGF) (FGF-7) and its receptor (KGFR) during reepithelialization of human skin. KGF mRNA levels increased rapidly by 8-10-fold and remained elevated for several days. In contrast, KGFR transcript levels decreased early but were significantly elevated by 8-9 d. A KGF-immunoglobulin G fusion protein (KGF-HFc), which specifically and sensitively detects the KGFR, localized the receptor to differentiating keratinocytes of control epidermis, but revealed a striking decrease in receptor protein expression during the intermediate period of reepithelization. Suramin, which blocked KGF binding and stripped already bound KGF from its receptor, failed to unmask KGFRs in tissue sections from the intermediate phase of wound repair. The absence of KGFR protein despite increased KGFR transcript levels implies functional receptor downregulation in the presence of increased KGF. This temporal modulation of KGF and KGFRs provides strong ...
Used in the prevention or treatment of oral mucoscitis (mouth ulcers arising from chemotherapy), Kepivance binds to the human keratinocyte growth factor (KGF) receptor on buccal cell surfaces. Kepivance acts as both a cell growth and survival factor by stimulating epithelial cell proliferation, differentiation, and migration around the tongue and mouth. The KGF receptor is found on many tissues particularly around the tongue, esophagus, salivary gland and other gastro-intestinal tract organs ...
KGF 2 Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 173 amino acids and having a molecular mass of 19.5kDa.
Faktor pertumbuhan keratinosit (Keratinocyte Growth Factor) adalah sebuah zat yang merangsang pertumbuhan sel-sel epitel yang melapisi permukaan mulut dan saluran usus.. ...
The mucosal immune system of the female reproductive tract (FRT) balances the dual functions of protection against invading pathogens and adaptation of the endometrial environment for successful fertilization and implantation. Growth factors are important in normal endometrial physiology and can act as mediators of some indirect effects of E 2. This thesis was undertaken to test the overall hypothesis that E 2 and keratinocyte growth factor (KGF) regulate the secretion of macrophage inflammatory protein 3α (MIP3α) and keratinocyte-derived chemokine (KC) by mouse uterine epithelial cells. Culture of polarized uterine epithelial cells with KGF increased both apical and basolateral secretion of MIP3α as well as basolateral secretion of KC. E 2 added to the culture media inhibited both constitutive and KGF-induced secretion of MIP3α, yet further increased KGF-induced basolateral KC secretion. The inhibition of constitutive MIP3α secretion by E 2 was mediated via the estrogen receptor. Other ...
Myeloablative conditioning results in thymic epithelial cell (TEC) injury, slow T-cell reconstitution, and a high risk of opportunistic infections. Keratinocyte growth factor (KGF) stimulates TEC proliferation and, when given preconditioning, reduces TEC injury. Thymocytes and TECs express androgen receptors, and exposure to androgen inhibits thymopoiesis. In this study, we have investigated whether TEC stimulation via preconditioning treatment with KGF and leuprolide acetate (Lupron), 2 clinically approved agents, given only before conditioning would circumvent the profound TEC and associated T-cell deficiency seen in allogeneic bone marrow transplant (BMT) recipients. Only combined treatment with KGF plus leuprolide acetate normalized TEC subset numbers and thymic architecture. Thymopoiesis and thymic output were supranormal, leading to the accelerated peripheral reconstitution of naive CD4 and CD8 T cells with a broad Vbeta repertoire and decreased homeostatic T-cell proliferation. Combined therapy
Keratinocyte growth factor (KGF), now known as fibroblast growth factor 7 (FGF7), is a member of the fibroblast growth factor (FGF) family of proteins that possess broad-ranging mitogenic and cell survival activities. KGF/FGF7 is also known as heparin-binding growth factor 7 (HBGF7). KGF displays mitogenic activity specific to epithelial cells; it is active predominantly in keratinocytes but not in fibroblasts or endothelial cells. Studies in rodents have implicated KGF in epithelial morphogenesis, re-epithelialization of wounds, hair development, and early lung organogenesis. KGF binds to fibroblast growth factor receptor 2b (FGFR2b).. ...
Keratinocyte growth factor (KGF), now known as fibroblast growth factor 7 (FGF7), is a member of the fibroblast growth factor (FGF) family of proteins that possess broad-ranging mitogenic and cell survival activities. KGF/FGF7 is also known as heparin-binding growth factor 7 (HBGF7). KGF displays mitogenic activity specific to epithelial cells; it is active predominantly in keratinocytes but not in fibroblasts or endothelial cells. Studies in rodents have implicated KGF in epithelial morphogenesis, re-epithelialization of wounds, hair development, and early lung organogenesis. KGF binds to fibroblast growth factor receptor 2b (FGFR2b).. ...
This study will look at the permeability, or leakiness of the airway epithelium (the inner lining of the lung) in asthmatic patients. Increased leakiness of this lining has been shown in asthmatic patients by other studies, not only in the lung but also possibly in the gut, perhaps reflecting a widespread defect. This leakiness may underline the interaction between the environment and a persons genetic make up, and may contribute to why some people get asthma, and how severe it is. Increased leakiness may allow increased exposure to inhaled allergic substances, helping to perpetuate the inflammation in the lungs that is a hallmark of asthma.. Specifically, this study will attempt to modify and reduce this permeability through the use of a substance called keratinocyte growth factor, or kgf. KGF is a naturally occuring human protein, which is involved in stimulating the growth of cells lining the layers of the skin and gut, helping to repair damage and maintain their structure. It has been ...
Fibroblast Growth Factor 21 (FGF21) is a novel target with potential anti diabetic properties that are useful for treatment of hyperglycemia, insulin resistance, hyperlipidemia and metabolic disease. Producing recombinant FGF21 by E. coli without using fusion proteins is time consuming and will produce low quantity products. In this study, to establish and test the efficiency of other expression methods, the complete fgf21 gene was constructed by overlapping PCR. The recombinant fgf21 genes were expressed successfully in E. coli (TB1) and in yeast (Pichia pastoris) under the control of maltose binding promoter and alcohol oxidase I promoter. The degree of success in terms of yield and functionality of the produced recombinant proteins in vivo were compared by using animal models. The result demonstrated that both expression systems can promote more soluble FGF21 levels, with less purification steps while preserving the bioactivity of the protein in vivo. The FGF21 produced in P. pastoris ...
Snail1, Snail2, and E47 promote mammary epithelial branching morphogenesis.: Several E-box-binding transcription factors regulate individual and collective cell
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KGF/FGF-7, Mouse, Recombinant; find Sigma-Aldrich-422426 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich.
Mao Q, Stinnett HK, Ho RK. Asymmetric cell convergence-driven zebrafish fin bud initiation and pre-pattern requires Tbx5a control of a mesenchymal Fgf signal. Development. 2015 Dec 15; 142(24):4329-39 ...
S. Korzh, Winata, C. Lanni, Zheng, W., Yang, S., Yin, A., Ingham, P., Korzh, V., and Gong, Z., The interaction of epithelial Ihha and mesenchymal Fgf10 in zebrafish esophageal and swimbladder development., Dev Biol, vol. 359, no. 2, pp. 262-76, 2011. ...
S. Korzh, Winata, C. Lanni, Zheng, W., Yang, S., Yin, A., Ingham, P., Korzh, V., and Gong, Z., The interaction of epithelial Ihha and mesenchymal Fgf10 in zebrafish esophageal and swimbladder development., Dev Biol, vol. 359, no. 2, pp. 262-76, 2011. ...
In Waterstons embryo of 27 somites, there is again a wide interval between lung and liver, and he shows a lung bud which can surely be interpreted as nothing but lung. In the earlier stages to which I have referred the lung bud is shown as being bifid at its caudal end, but such a bifid condition is not present in the more caudal swelling of Thompsons embryo, whereas it is present in the cranial swelling which Thompson calls lung bud. Furthermore, if Grosser is correct in his interpretation of the more caudal swelling as lung bud, itwould mean that this structure would come to an end right up against the dorsal surface of the liver bud, behind which it is hidden. The resemblance between Thompsons specimen and my own is so close that I find it difficult to believe that Grossers interpretation is correct. ...
of 27 somites, there is again a wide interval between lung and liver, and he shows a lung bud which can surely be interpreted as nothing but lung. In the earlier stages to which I have referred the lung bud is shown as being bifid at its caudal end, but such a bifid condition is not present in the more caudal swelling of Thompsons embryo, whereas it is present in the cranial swelling which Thompson calls lung bud. Furthermore, if Grosser is correct in his interpretation of the more caudal swelling as lung bud, itwould mean that this structure would come to an end right up against the dorsal surface of the liver bud, behind which it is hidden. The resemblance between Thompsons specimen and my own is so close that I find it difficult to believe that Grossers interpretation is correct ...
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Rabbit polyclonal antibody raised against recombinant FGF7. Recombinant protein corresponding to human FGF7. (PAB17966) - Products - Abnova
keratinocyte Definition, keratinocyte Best Plays of keratinocyte in Scrabble® and Words With Friends, Length tables of words in keratinocyte, Word growth of keratinocyte, Sequences of keratinocyte
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Background: Acute respiratory distress syndrome (ARDS) caused by high pathogenic avian influenza (HPAI) H5N1 virus infection has resulted in severe illness and high mortality rates among patients. Patients with ARDS are often characterized by impaired alveolar fluid clearance and alveolar edema. An understanding of the mechanism responsible for human alveolar edema will lead to the development of novel therapeutic treatments for ARDS patients. We hypothesized that the paracrine soluble factors angiopoietin-1 (Ang-1) and keratinocyte growth factor (KGF) can resolve alveolar fluid clearance by up-regulating the expression of major sodium and chloride transporters impaired by HPAI H5N1 virus infection. Materials and Methods: Human alveolar epithelial cells grown on transwell inserts were infected with HPAI H5N1 (A/HK/483/97) and low pathogenic avian influenza (LPAI) H1N1 (A/HK/54/98) viruses at MOI 0.1 or incubated with conditioned culture medium containing Ang-1 and/or KGF. At 24 and 48 h ...
TY - JOUR. T1 - Erratum to. T2 - Keratinocyte growth factor in acute lung injury to reduce pulmonary dysfunction - a randomised placebo-controlled trial (KARE): study protocol. AU - Cross, Laurence J M. AU - OKane, Cecilia M. AU - McDowell, Cliona. AU - Elborn, Jospeh J. AU - Matthay, Michael A. AU - McAuley, Daniel F. PY - 2017/5/11. Y1 - 2017/5/11. KW - Published Erratum. U2 - 10.1186/s13063-017-1930-7. DO - 10.1186/s13063-017-1930-7. M3 - Article. C2 - 28494790. VL - 18. SP - 214. JO - Trials. JF - Trials. SN - 1745-6215. IS - 1. ER - ...
Palifermin (trade name Kepivance, marketed by Biovitrum) is a truncated human recombinant keratinocyte growth factor (KGF) produced in Escherichia coli. KGF stimulates the growth of cells that line the surface of the mouth and intestinal tract. When patients with blood cancers (leukemia and lymphoma) receive high dose chemotherapy and radiation therapy to undergo bone marrow transplantation, they usually get severe oral mucositis. Palifermin reduces the incidence and duration of severe oral mucositis by protecting those cells and stimulating the growth of new epithelial cells to build up the mucosal barrier. Palifermin is also being studied in the prevention and treatment of oral mucositis and dysphagia (difficulty swallowing) in other types of cancer. Keratinocyte growth factor (KGF) resides in the family of fibroblast growth factor (FGF). The drugs target is the KGF receptor. Through the binding of this drug to the aforementioned receptor, Palifermin stimulates epithelial cell proliferation, ...
0014]Non-limiting examples of low molecular weight EGFR inhibitors useful in practicing the present invention include any of the EGFR inhibitors described in the following patent publications, and all pharmaceutically acceptable salts and solvates of said EGFR inhibitors: European Patent Application EP 520722, published Dec. 30, 1992; European Patent Application EP 566226, published Oct. 20, 1993; PCT International Publication WO 96/33980, published Oct. 31, 1996; U.S. Pat. No. 5,747,498, issued May 5, 1998; PCT International Publication WO 96/30347, published Oct. 3, 1996; European Patent Application EP 787772, published Aug. 6, 1997; PCT International Publication WO 97/30034, published Aug. 21, 1997; PCT International Publication WO 97/30044, published Aug. 21, 1997; PCT International Publication WO 97/38994, published Oct. 23, 1997, PCT International Publication WO 97/49688, published Dec. 31, 1997; European Patent Application EP 837063, published Apr. 22, 1998; PCT International Publication ...
Fibroblast growth factors (FGFs) and their high-affinity receptors contribute to the autocrine growth stimulation in several human malignancies. Here, we describe that FGF18 expression is up-regulated in 34/38 colorectal tumours and is progressively enhanced during colon carcinogenesis reaching very high levels in carcinoma. Moreover, our data suggest that FGF18 affects both tumour cells and tumour microenvironment in a pro-tumorigenic and pro-metastatic way. Addition of recombinant FGF18 to the culture media of slowly growing colorectal tumour cell lines LT97 and Caco-2 stimulated proliferation. Phosphorylation of externally regulated kinase 1/2 and S6 was increased already 5 min after growth factor addition. SW480 cells, endogenously producing large amounts of FGF18, were not affected in this setting, but recombinant FGF18 supported tumour cell survival under conditions of serum starvation. Down-modulation of endogenous FGF18 production by small interference RNA (siRNA) significantly reduced ...
TY - JOUR. T1 - Expression of Spred and Sprouty in developing rat lung. AU - Hashimoto, Shuichi. AU - Nakano, Hiroshi. AU - Singh, Gurmukh. AU - Katyal, Sikandar. N1 - Funding Information: This work was supported by a grant from the National Institutes of Health (HL 62397). We thank Dr. A. Paula Monaghan-Nichols for advice.. PY - 2002/12. Y1 - 2002/12. N2 - Sproutys and Sprouty-related proteins, Spred-1 and -2, are known inhibitors of fibroblast growth factor (FGF) signaling, which plays key role in lung branching morphogenesis and the development of other tissues. The present study demonstrates that Spreds are expressed in a variety of rat embryonic tissues (brain, intestine, heart, skin) including the lung. In the embryonic lung, Spreds and Sproutys are expressed during the early stages of branching morphogenesis, but their expression profiles are both distinct and oveflapping. Spreds are predominantly expressed in mesenchymal cells in contrast to Sproutys, which are abundantly expressed in ...
Fgf6, a member of the Fibroblast Growth Factor (FGF) family, is developmentally regulated and its expression is highly restricted in the adult. To gain further insight into the role of Fgf6, we studied its expression during embryogenesis using RNA in situ hybridization. Fgf6 expression is restricted to developing skeletal muscle. Fgf6 transcripts are first detected in the somites at 9.5 days post-conceptus, and expression continues in developing skeletal muscles up to at least 16.5 days post-conceptus. Fgfr4 is a putative receptor for FGF6. Its pattern of expression during myogenesis overlaps that of Fgf6, but both genes are not expressed in exactly the same population of cells. In addition, recombinant FGF6 protein is able to repress the terminal differentiation of myoblasts in culture, providing additional support to the concept that FGF6 plays an important role in myogenesis.. ...
J:35179 Ozawa K, Uruno T, Miyakawa K, Seo M, Imamura T, Expression of the fibroblast growth factor family and their receptor family genes during mouse brain development. Brain Res Mol Brain Res. 1996 Sep 5;41(1-2):279-88 ...
Mouse monoclonal antibody raised against recombinant FGF2. Recombinant protein corresponding to human FGF2. (MAB6257) - Products - Abnova
Branching morphogenesis, the creation of branched structures in the body, is a key feature of animal and plant development. This book brings together, for the first time, expert researchers working on
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Mucositis: Treatment of mucositis is mainly supportive, helping to alleviate redness and pain. Oral hygiene is the mainstay of treatment; individuals are encouraged to clean their mouth every four hours and at bedtime, more often if the mucositis becomes worse. Water-soluble jellies can be used to lubricate the mouth. Salt mouthwash can soothe the pain and keep food particles clear so as to avoid infection. Individuals are also encouraged to drink plenty of liquids, at least three liters a day, and avoid alcohol. Citrus fruits, alcohol, and foods that are hot are all known to aggravate mucositis lesions. Medicinal mouthwashes may be used such as chlorhexidine (Peridex ) and viscous lidocaine (Xylocaine viscous ) for the relief of pain. Palifermin (Kepivance ), is a human KGF (keratinocyte growth factor) that has been shown to enhance epithelial cell proliferation, differentiation, and migration. Experimental therapies have been reported, including the use of cytokines and other modifiers of ...
Abstract: : Purpose: To establish a binary inducible transgenic mouse model that can be used to elucidate the roles of growth factors, e.g., FGF-7, on corneal biology. It has been suggested that FGF-7 (KGF, keratinocyte growth factor) serves as a paracrine that modulates the growth of corneal epithelial cell. The present studies are to investigate the effect of excess FGF-7 on corneal epithelial cells in a binary tetracycline inducible transgenic mouse line. Methods: A keratocyte-specific 3.2 kb murine keratocan promotor (Kerapr) has been used to prepare Kerapr-rtTA transgenic (KeraprrtTA/+) mice that constitutively overexpress rtTA (reverse tetracycline transcription activator) in cornea. The KeraprrtTA/+ mice were crossed with tet-OFGF7/FGF7 mice to produce compound heterozygous transgenic (KeraprrtTA/+•tet-OFGF7/+) mice, which were fed doxycycline water (0.5 mg/ml) for one week. The experimental mice were i.p. injected with BrdU (100 µg/g body weight) 2 h prior to sacrifice. The enucleated ...
Am. J. Respir. Cell Mol. BioI. 1996. Here, the authors studied the expression of different laminin chains and their integrin receptors in fetal and adult lung by immunohistochemistry. Special attention was focused on the changes in the expression of these proteins during the development from the pseudoglandular (PG) and canalicular stages to adult lung and on the possible implications of the changes for the normal lung development. The most significant changes in the expression pattern were found during the development from the PO stage to the canalicular stage. Basement membranes (BM) of both the epithelial buds and the becoming bronchi showed reactivity for laminin α1, a3, and B3 chains at all stages. The a2 chain was expressed only in the epithelial buds at the PO stage, and could not be found in any epithelial structures at the canalicular stage. Similarly, at the PG stage the B2 chain was expressed in BMs of both epithelial buds and bronchi but disappeared from the bronchial BM before the ...
CopperICE Cream helps heal wounds, firm skin and elasticity, reduce the appearance of wrinkles and promote cellular turnover in addition to promoting keratinocyte growth.
Golgi coated bud formation is blocked by ARF depletion and restored by purified ARF. Replicas of Golgi membranes after a 15-min transport incubation were prepa
The tumor microenvironment is gaining importance in the regulation of tumorigenesis, invasion and metastasis. Loss of PTEN, a negative regulator of AKT, in stromal fibroblasts results in an increased tumor occurrence in ErbB2 expressing murine mammary tumors. Furthermore, we have shown that activation of AKT in stromal fibroblasts, following loss of the Retinoblastoma Protein (Rb), induces epithelial invasions in organotypic raft cultures, via an increase in Keratinocyte Growth Factor (KGF) expression. In addition, we have shown that loss of the PTEN tumor suppressor in stromal fibroblasts and subsequent activation of AKT, increases invasive potential of Human Papilloma Virus Type 16 E6 and E7 expressing keratinocytes. This is mediated by an increase in KGF expression. There are three isoforms of AKT expressed in human fibroblasts, AKT1, AKT2 and AKT3. By depleting each individual AKT isoform in stromal fibroblasts we have been able to establish that AKT2 is essential in regulating the cross ...
Mucositis: Treatment of mucositis is mainly supportive, helping to alleviate redness and pain. Oral hygiene is the mainstay of treatment; individuals are encouraged to clean their mouth every four hours and at bedtime, more often if the mucositis becomes worse. Water-soluble jellies can be used to lubricate the mouth. Salt mouthwash can soothe the pain and keep food particles clear so as to avoid infection. Individuals are also encouraged to drink plenty of liquids, at least three liters a day, and avoid alcohol. Citrus fruits, alcohol, and foods that are hot are all known to aggravate mucositis lesions. Medicinal mouthwashes may be used such as chlorhexidine (Peridex ) and viscous lidocaine (Xylocaine viscous ) for the relief of pain. Palifermin (Kepivance ), is a human KGF (keratinocyte growth factor) that has been shown to enhance epithelial cell proliferation, differentiation, and migration. Experimental therapies have been reported, including the use of cytokines and other modifiers of ...
Catalog No :RS01Ab0516 Organism- Rat Clonality :Polyclonal Host :Rabbit Application :WB, ICC, IHC-P, IHC-F, ELISA Concentration : 200ug/ml UOM : 100ug Conjugate : No Conjugate Immunogen Information : Immunogen : Recombinant FGF1 (Phe16~Asp155) expressed in E.coli. Antibody Specificity : The antibody is a rabbit polyc
Catalog No :RS01Ab0513 Organism- Human Clonality :Polyclonal Host :Rabbit Application :WB, ICC, IHC-P, IHC-F, ELISA Concentration : 200ug/ml UOM : 100ug Conjugate : No Conjugate Immunogen Information : Immunogen : Recombinant FGF1 (Met1~Asp155) expressed in E.coli. Antibody Specificity : The antibody is a rabbit polyc
Androgen-induced growth factor (AIGF/FGF-8) has purified from a mouse mammary carcinoma cell line and its cDNA cloning revealed that AIGF is the eighth member of the fibroblast growth factor family. To clarify a biological role of FGF-8, Northern blot analysis of various adult tissues was carried ou …
In cosmetics, Antarcticine® maintains its natural bioprotective properties and promotes keratinocyte growth and fibroblast adhesion for a skin regenerating effect and enhanced wound healing.
Fibroblast growth factor-21 (FGF21) belongs to the large FGF family which has at least 23 members. Along with FGF-19/15 and FGF-23, FGF-21 is categorized as a member of the atypical FGF subfamily, as it must be complexed to the Klotho co-receptor in order to bind to the FGF receptors and activate...
Verzeichniss bekannter Schmettlinge, 1816-[1826] Verz. bek. Schmett. (1): [1-3], 4-16 (1816), (2): 17-32 (1819), (3): 33-48 (1819), (4): 49-64 (1819), (5): 65-80 (1819), (6): 81-96 (1819), (7): 97-112 (1819), (8): 113-128 (1819), (9): 129-144 (1819), (10): 145-160 (1819), (11): 161-176 (1819), (12): 177-192 (1820), (13): 193-208 (1820), (14): 209-224 (1821), (15): 225-240 (1821), (16): 241-256 (1821), (17): 257-272 (1823), (18): 273-288 (1823), (19): 289-304 (1823), (20): 305-320 (1825), (21): 321-336 (1825), (22): 337-352 (1825), (23-27): 353-431 ([1825 ...