TY - JOUR. T1 - Twin to twin transfusion syndrome. AU - Bhat, R.. PY - 2010/1/1. Y1 - 2010/1/1. N2 - Twin to twin transfusion syndrome (TTTS) is a specific condition complicating 10-15% of monochorionic multiple pregnancy. Intertwin vascular anastomoses and transfusion is a normal event. Syndrome develops when blood flow is unbalanced. Recent studies suggest a paucity of bi-directional superficial anastomoses failing to compensate for hemodynamic imbalance resulting from unidirectional transfusion along deeper arterio-venous anastomoses. TTTS is associated with high rates of perinatal mortality. Acute and chronic forms exist and severity varies. The donor twin is often smaller, hypovolemic, anemic and develops congestive heart failure. The recipient is usually heavier and polycythemic. Antenatally, second trimester ultrasound usually detects the condition. Serial amnioreduction is the recommended therapy. Postnatally, intertwin haemoglobin and birth weight differences along with pallor in one ...

Twin to twin transfusion syndrome is a rare but dangerous pregnancy defect requiring quick diagnosis and intervention. Click to learn more about its effects.

TY - JOUR. T1 - Twin-twin transfusion syndrome in a dizygotic monochorionic-diamniotic twin pregnancy. AU - Quintero, R. A.. AU - Mueller, O. T.. AU - Martínez, J. M.. AU - Arroyo, J.. AU - Gilbert-Barness, E.. AU - Hilbelink, D.. AU - Papenhausen, P.. AU - Sutcliffe, M.. PY - 2003/10. Y1 - 2003/10. N2 - We present a case of twin-twin transfusion syndrome with discordant gender. Monochorionicity was confirmed by surgical pathology. Cytogenetic analysis showed normal 46,XX and 46,XY karyotypes. Microsatellite analysis using reliable pericentromeric markers was consistent with dispermic fertilization of two separate ova. This suggests that monochorionicity, rather than zygosity, may be responsible for the development of placental vascular anastomoses.. AB - We present a case of twin-twin transfusion syndrome with discordant gender. Monochorionicity was confirmed by surgical pathology. Cytogenetic analysis showed normal 46,XX and 46,XY karyotypes. Microsatellite analysis using reliable ...

Twin-to-twin transfusion syndrome is a rare condition that occurs when blood moves from one identical twin (the Òdonor twinÓ) to the other (the Òrecipient twinÓ) while in the womb. The donor twin may be born smaller, with paleness, anemia, and dehydration. The recipient twin may be born larger, with redness, too much blood, and increased blood pressure, resulting in an increased risk for heart failure. Treatment may require repeated amniocentesis during pregnancy. Fetal laser surgery may be done to interrupt the flow of blood from one twin to the other. After birth, treatment depends on the infants specific symptoms. The donor twin may need a blood transfusion to treat anemia. The recipient twin may need to have the volume of body fluid reduced. This may involve an exchange transfusion. Medications may be given to treat heart failure in the recipient twin ...

Twin-to-twin transfusion syndrome is a rare condition that occurs when blood moves from one identical twin (the Òdonor twinÓ) to the other (the Òrecipient twinÓ) while in the womb. The donor twin may be born smaller, with paleness, anemia, and dehydration. The recipient twin may be born larger, with redness, too much blood, and increased blood pressure, resulting in an increased risk for heart failure. Treatment may require repeated amniocentesis during pregnancy. Fetal laser surgery may be done to interrupt the flow of blood from one twin to the other. After birth, treatment depends on the infants specific symptoms. The donor twin may need a blood transfusion to treat anemia. The recipient twin may need to have the volume of body fluid reduced. This may involve an exchange transfusion. Medications may be given to treat heart failure in the recipient twin ...

NIH Rare Diseases : 50 twin to twin transfusion syndrome (ttts) is a rare condition that occurs during a twin pregnancy when blood moves from one twin (the donor twin) to the other (the recipient twin) while in the womb. ttts is a complication that specifically occurs in identical (monozygotic) twin pregnancies that share the same egg sac (monochorionic) that may or may not share the same amniotic sac (monoamniotic). ttts usually develops between 15 and 26 weeks of pregnancy. the donor twin may be born smaller, with paleness, anemia, and dehydration. the recipient twin may be born larger, with redness, too much blood, and increased blood pressure, resulting in an increased risk for heart failure. treatment may require repeated amniocentesis during pregnancy. fetal laser surgery may be done to interrupt the flow of blood from one twin to the other. after birth, treatment depends on the infants specific symptoms. the donor twin may need a blood transfusion to treat anemia. the recipient ...

Optimal management of twin-twin transfusion syndrome (TTTS) in monochorionic diamniotic (MCDA) twins remains challenging. Our aim was to investigate whether Vector Velocity Imaging (VVI), a non-Doppler speckle tracking ultrasound technology, was feasible in twin pregnancies and could aid management of TTTS.. VVI was performed during routine fetal echocardiograms in 55 women pregnant with monochorionic diamniotic (MCDA) twins (27 affected by TTTS and 28 non TTTS controls). Right (RVs) and left (LVs) free wall ventricular Lagrangian strain was measured off-line using Syngo VVI tracking of four-chamber clips recorded with dummy ECG to retain high frame rates for analysis. Within-twin pair differences in strain and relationship to Quintero staging at presentation were analysed.. Gestational age was similar between non TTTS controls and TTTS cases (22+4 vs 21+2; p=0.26). VVI strain measurements could be analysed in 182/200 (91%) TTTS and 94/112 (84%) non TTTS control ventricles. Within-pair strain ...

Background: DNA methylation (DNAm), is an important transcriptional regulation mechanism, relevant to various diseases. Twin-to-twin transfusion syndrome (TTTS) is a complication in twin pregnancies resulting from disproportionate blood circulation. Survivors of TTTS show a hi...

Findings suggest twin pregnancy of monochorionic diamniotic (MCDA) type. Although the intertwin membrane is not clearly seen, the presence of two yolk sac is highly suggestive of an MCDA (rather than MCMA) pregnancy. In this case, there was rel...

This case demonstrates features of twin-twin transfusion syndrome with fetal MRI, prior to and after successful laser photocoagulation. Both fetal brains are mildly abnormal. The donor twin has borderline ventriculomegaly, and the recipient twin...

The risk of perinatal morbidity and mortality in twins is 3-7 times higher than in singletons. In comparison to dichorionic twins, monochorionic twins are at increased risk for perinatal mortality and serious morbidity. In both type of twins growth discordance can occur. Discordant growth of dichorionic twins could be due to differences in placental mass or differences in placental parenchymal lesions, whereas birth weight discordancy in monochorionic twins is caused by placental vascular anastomoses. In this review the different types of complications (acardiac twins, acute and chronic twin-twin transfusion syndrome) due to different combinations of vascular anastomoses are discussed in relation to a computer model developed to gain more insight into the development of the twin-twin transfusion syndrome. The angioarchitecture of 395 monochorionic twin placentas was studied. Mortality was highest in the absence of an arterio-arterial anastomosis (42%) and lowest in the presence of an ...

Twin-twin transfusion syndrome (TTTS) happens when identical twins share a placenta. Learn about causes, diagnosis and treatments, including laser surgery.

TY - CHAP. T1 - Twin reversed arterial perfusion (TRAP) sequence. T2 - In-utero treatment. AU - Farmer, Diana L. AU - Løfberg, Katrine M.. PY - 2009/1/1. Y1 - 2009/1/1. N2 - Background: Twin reversed arterial perfusion (TRAP) sequence or acardiac twinning is a rare congenital anomaly unique to monozygotic multiple gestations. Existence of TRAP requires two conditions: (1) pump or forward flow failure in the acardiac twin and (2) a set of arterioarterial and venovenous placental anastomoses connecting the acardiac and pump twins circulatory systems. It is considered the most severe malformation of twinning seen in humans. Other historical though less commonly used terms include chorioangiopagus parasiticus and acardiac monster. Incidence is estimated to be 1:35000 pregnancies or 1% of all monochorionic pregnancies [1, 2], though it may be higher given that some cases of TRAP may go undiagnosed due to early pregnancy loss or reabsorption of the acardiac twin [3]. Pathophysiology: In TRAP, one ...

Twin-twin transfusion syndrome (TTTS) is a serious condition occurring in approximately 10 percent to 15 percent of pregnancies in which identical twins share

Patients undergo a detailed ultrasound examination to rule out the presence of congenital anomalies, and to assess the hemodynamic status of the fetuses. Patients with confirmed TTTS will be considered candidates for the trial. Patients will be counseled about the risks and benefits of all treatment options and will be free to choose any treatment option. They will then be asked to sign an informed consent. The procedure will be performed under local anesthesia. After a 2-3 mm skin incision, and under ultrasound guidance, the trocar will be introduced in the amniotic cavity of the Recipient twin. The communicating vessels will be located endoscopically and will be lasered with YAG laser energy. An accessory port may be required in some cases. The procedure will be monitored both endoscopically and sonographically. The presence of fetal heart activity will be noted often during the procedure. An amniodrainage of the larger sac may be performed at the time of the procedure. The patient will remain ...

RESULTS. The median gestational age at initial presentation, laser photocoagulation, and delivery were 22 (range, 16-27) weeks, 23 (18-28) weeks, and 32 (21-37) weeks, respectively. To improve the visualisation, in three cases amnio-exchange was undertaken; the procedure was abandoned in two due to poor visualisation. The overall fetal survival rate, the double infant survival rate, and survival rate for at least one twin were 72% (43/60), 60% (18/30), and 83% (25/30), respectively. The most common peri-operative complication was bleeding from the uterine wall into the amniotic cavity, which affected three (10%) patients ...

The recipient has cardiovascular changes including atrioventricular valve regurgitation, diastolic dysfunction and pulmonary stenosis/atresia. The maladaptive response to vascular changes determines a constant decreased blood flow in the donor that permanently modifies the arterial structure leading to postnatal alterations in the vascular system. Fetoscopic LASER surgery of placental vascular anastomoses may disrupt the underlying pathophysiology and improves cardiovascular function with normalization of systolic and diastolic function within weeks after treatment. ...

Twin reversed arterial perfusion sequence (TRAP) is a rare complication of spontaneous Dichorionic triamniotic triplet pregnancy and only few cases are documented. We rep..

Ashlea was born extremely prematurely due to severe Twin-Twin Transfusion Syndrome. She weighed 570gm at birth (1 pound 4). She had a VERY rocky journey through the NICU and nearly didnt make it on several occasions. As a result of her difficult start to life she has been left with chronic renal failure (she will require a kidney transplant in the next few years), cerebral palsy (spastic diplegia), a developmental delay and she is blind. Ashlea has had hernia surgery, a fundoplication and has a g-tube. Ashlea has surprised her doctors by recently learning to crawl and by starting to say some words, and at the age of 3 she has just started w-sitting for short periods of time. She is very cute and very loved. You can follow her journey at: http://thinkingofstartingablog.blogspot.com/ ...

AURORA, Colo. - They look like the picture of a happy family, but just last year, Kristi Morris and her twin daughters almost didnt make it.. I thought to myself, theres no way all three of us are going to survive this pregnancy, said Morris.. At 19 weeks, she and her husband, Keith, got the diagnosis: Twin-to-Twin Transfusion Syndrome, TTTS.. We still didnt understand that it could go from normal babies to dead babies really fast, said Keith.. Without treatment, this is close to 95 percent fatal, said Dr. Tim Crombleholme, with Childrens Hospital of Colorado. With TTTS, one twin gets too much amniotic fluid, and the other doesnt get enough. Both are in critical danger.. I thought to myself, if they survive this, Im lucky but I have to be realistic, said Kristi Morris.. But then, the Morris family saw a 7NEWS story last year, profiling the Ballard family, whose TTTS girls survived and thrived.. That gave me hope, said Morris.. Last year, Laura Ballard had a rare laser surgery ...

TRAP sequence is a very rare condition that only occurs in twin pregnancies that share a common placenta (monochorionic twins). In TRAP sequence, one twin is usually developmentally normal and the other twin has a serious condition.

Of those 145 pregnancies diagnosed with Twin to Twin Transfusion Syndrome, there were 34 cases of single fetal demise after laser therapy - this means that one twin died in 24.1 percent of the cases treated at the centre. Out of the 34 babies, 26 donors and 8 recipients died. This means that out of the 145 pregnancies, the donor baby died in 18.4 percent of cases. The recipient baby died in 5.7 percent of cases. ...

How is his breathing these days? Its a question I get a lot - though I have few definitive answers.. Our identical twins Tim and Cary were born 11 weeks early after developing Twin to Twin Transfusion Syndrome (TTTS) where one was getting more blood than the other. They were born weighing 2.7 pounds and 1.13 pounds. Both were diagnosed with Chronic Lung Disease. And once discharged from the Neonatal Intensive Care Unit (NICU) approximately three months later, only Cary came home on oxygen.. One morning, a few weeks after coming home, Cary refused to take his bottle. The deafening alarms on his pulse oximeter were constant and my worry was growing. A few days prior we had taken him to a doctor who told us he had a virus that would soon run its course. But he wasnt getting better. A phone call with the pulmonologist ended with us buckling Cary into his car seat to take him to the emergency room. But then everything dropped - his oxygen levels, his heartrate. Panicked, we called the paramedics. ...

Hi! Im Amber. I have 3 children (all born healthy with completely normal low risk pregnancies), and Im 7 weeks pregnant with twins. I spoke with my midwife today and was informed that I tested positive for E antibodies. She said my level was only 1, which Im assuming she meant 1:1? I was already very worried about this pregnancy, since we are not sure yet whether my identical twins are mo-di or mo-mo (mo-mo only has a 50% survival rate). Its a high risk pregnancy either way. I will be monitored very closely to make sure the twins dont develop twin to twin transfusion syndrome. I will most likely have ultrasounds every two weeks. Now that I know about this new twist - with the E antibodies - I am terrified! Please share any info or your experiences with anti-E. How worried should I be at this point? Thanks!

Cherie Lamartina underwent fetal surgery for twin reversed arterial perfusion (TRAP) sequence at The Childrens Hospital of Philadelphia to save Taylor.

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Twin reversed arterial perfusion (TRAP) sequence is a rare condition that occurs in pregnancies of identical twins that share a common placenta.

Overall, amnioreduction is an easy procedure. The rationale behind it is that the normalizing of fluid levels reduces maternal discomfort, improves uteroplacental perfusion (especially in the setting of presumed twin-twin transfusion syndrome [TTTS]), and prolongs pregnancy.

Background Twin-twin transfusion syndrome (TTTS) is a highly morbid condition in which treatment exists, but the pregnancy remains high-risk until delivery. It may have serious sequelae, including fetal death, and in the longer term, neurodevelopmental problems. The aim of this study is to assess antenatal and postnatal parental attachment and depressive symptoms in those with pregnancies affected by TTTS. Methods Couples attending for fetoscopic laser ablation treatment of TTTS were asked to complete Condons Maternal/Paternal Antenatal/Postnatal Attachment Scale as appropriate, and the Edinburgh Depression Scale the day before ablation, 4 weeks post-ablation, and 6-10 weeks postnatally. Results 25/27 couples completed the pre-ablation questionnaire (median gestational age 19 + 3 weeks [interquartile range 18 + 2-20 + 6]). 8/18 eligible couples returned the post-ablation questionnaire. 5/17 eligible couples returned the postnatal questionnaire. There was no significant difference in ...

Video articles in JoVE about patient safety include Safety Checks and Five Rights of Medication Administration, Setting Up a Stroke Team Algorithm and Conducting Simulation-based Training in the Emergency Department - A Practical Guide, Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management, Whole-body PET/MRI of Pediatric Patients: The Details That Matter, Performing Behavioral Tasks in Subjects with Intracranial Electrodes, Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators, General Approach to the Physical Exam, Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis, Palpation, Bioelectric Analyses of an Osseointegrated Intelligent Implant Design System for Amputees, Isolation and Quantification of Botulinum Neurotoxin From Complex Matrices Using the BoTest Matrix Assays, Techniques for Processing

See how laser surgery dealt with the often fatal twin-to-twin transfusion syndrome that threatened this moms unborn boys, and how they fared after birth.

EvergreenHealths Maternal-Fetal Medicine experts can diagnose, treat and help you manage pregnancy complications, including surgical treatment for Twin-to-Twin Transfusion Syndrome. We offer less-invasive prenatal testing.

In addition, Ive participated in a few C-sections and a tubal ligation, reminding me how much I like the operating room setting and dissection. Ive assessed patients in triage for preterm labor, mastitis from breastfeeding, and bogus chief complaints (a fifteen year old came in with her friends because they wanted to see the fetus on ultrasound). But the most interesting patients are often transferred from outside hospitals or fetal treatment patients. Weve had a twin gestation where one twin has a life-threatening arrhythmia; how do you selectively control one twins heart rate? Can you convert someone in utero? We have people with peripartum cardiomyopathy, twin-twin transfusion syndrome, and unstoppable preterm labor. Some transfers are unbelievable: a 23 weeker who was delivered by crash C-section at an outside hospital for an unclear indication (very sad case, the baby is going to die and the mother is a 17 year old). Some transfers are fascinating: a repeat C-section for a patient with ...

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Question - Pregnant. Ultra sound scan showed monochorionic twins. Meaning? . Ask a Doctor about Gestational sac, Ask an OBGYN, Gynecologic Oncology

This moms unborn children suffered from Twin to Twin Transfusion (TTTS); she had to carry one of her dead babies for weeks. Now shes spreading awareness.

is said of a fetus who does not grow as fast as he should, often because not enough nutrients or not enough blood (and oxygen) arrive to him, or because the fetus has to work harder than usual. In twin-to-twin transfusion, it is often seen in the donor twin, who has to pump blood to himself and to the recipient twin. Intrauterine growth retardation can be seen by ultrasound, when the fetus appears smaller than expected for a given gestational age. At birth, this will lead to a baby who is small for gestational age ...

Brother, Cells, Children, Chromosome, Chromosome 12, Cytogenetic, Fluorescence, Hair, Hair Follicle, Hair Follicles, Lymphocytes, Mosaicism, Phenotype, Report, Syndrome, Tetrasomy, Tissues, Trisomy, Twin, Twin Transfusion

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I had a red and white set of twins - does this mean I had TAPS?. Its entirely possible. However, bear in mind that TTTS also can result in a red and white twins combination. (Remember, TTTS is also caused by too much blood in one twin, the difference is that TAPS is too many red blood cells only). If, when your babies are born, you have a red and white pair, insist that they test their blood for the haematocrit levels. This will help with the necessary treatments for polycythemia and anaemia) Without these readings though, its virtually impossible for the man on the street to say yes. Remember, TAPS is a silent disease - there are not many external signs it is happening.. It is also important to remember that TAPS is not acute end stage TTTS. It is caused by connections less than one millimetre, and over a long period of time. TAPS requires different handling due to the density of the blood in the recipient.. Can I do anything to prevent TTTS or TAPS?. In a nutshell, no. There is no surefire ...

A lone survivor of twin-to-twin transfusion (T2T) syndrome*, Hayden has had to battle numerous health complications throughout his short life, including two strokes that made him quadriplegic before he was six.. Because of his paralysis, Hayden developed issues with his neck and throat which meant that he cant speak properly and has to communicate through eye-point technology - an ongoing and difficult learning process. Despite his tribulations, Haydens mother Samantha says he has an irrepressible personality that shines through.. Hes a big smiler and never seems to let anything get him down. He loves seeing other people have fun, because he takes a lot of joy out of that, says Samantha. Hes a real water baby and hes been surfing with the Disabled Surfing Association, which he absolutely loved. He places no limits on himself and is actually a bit of a daredevil! After hearing Haydens story, Satans Little Helper decided to help him reclaim some of his independence by equipping him with ...

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Dr. MFM came into the ultrasound room about ten minutes into the ultrasound, which was really rare. Usually, hes like the great and powerful Oz and just watches from behind his green curtain, commenting only after the test is completed. You have TTTS. Ive called my former colleague in Miami so that you can go…

目的 通过对单绒毛膜双胎胎盘浅表吻合血管、胎盘份额、脐带附着位置的比较,探讨双胎输血综合征胎盘(TTTS)结构的特点.方法 收集2013年6月至2014年6月于北京大学第三医院终止妊娠后确定的单绒毛膜双胎共97例,剔除分娩后胎盘破损或孕期行胎儿镜激光治疗的胎盘18例,共取得79例孕期未行胎儿镜激光治疗且分娩后完整保存的胎盘,对该79例胎盘行浅表血管灌注.剔除选择性官内生长受限(sIUGR)胎盘23例,对TTTS胎盘24例和无并发症单绒毛膜双胎(未发生TTTS、sIUGR等复杂性双胎妊娠)胎盘32例进行比较研究.结果 ...

by La Belle Province By Gregory McCormick, Director of English Programming for the Blue Metropolis International Literary Festival. I... Read More ...

This page provides relevant content and local businesses that can help with your search for information on TTTS Treatment. You will find informative articles about TTTS Treatment, including Twin-to-Twin Transfusion Syndrome (TTTS). Below you will also find local businesses that may provide the products or services you are looking for. Please scroll down to find the local resources in Salt Lake City, UT that can help answer your questions about TTTS Treatment.

Twin reversed arterial perfusion sequence is a rare and potentially lethal condition affecting approximately 1% of monochorionic twin pregnancies and 1 in 35,000 pregnancies overall. An apparently normal (pump) twin perfuses its severely malformed cotwin with deoxygenated blood via retrograde flow in direct arterioarterial anastomoses between the umbilical arteries of each twin. Fetal intestinal volvulus is a rare condition usually manifesting after birth. We report a unique case of twin reversed arterial perfusion sequence in association with intestinal volvulus in the surviving pump twin. A 32-year-old Hispanic primigravida was referred to our clinic after a fetoscopy procedure of laser photocoagulation of anastomoses at 18 weeks of gestation. Follow up scans in the ex-pump twin revealed dilated bowel loops and a typical

The aim of this study was to report the results of the first 10 cases of fetoscopic laser surgery for twin-to-twin transfusion syndrome by the Rotunda Hospital Fetal Treatment Programme. All cases of severe TTTS managed by our team from 2006 to 2007 were included. All fetoscopic laser surgeries were performed by a single specialist in fetal medicine. All pregnancies were followed up to pregnancy completion and a minimum of six weeks neonatal life. Laser surgeries were performed with ultrasound guidance and percutaneously using local anaesthesia via a 2.8mm rigid fetoscope. Selective laser ablation of placental vessels was accomplished with a neodymium:YAG laser. The first 10 cases of severe TTTS managed by our team are reported. Laser ablation of placental vessels was accomplished successfully in all cases. Two pregnancies were complicated by preterm premature rupture of membranes before 22 weeks and both pregnancies were lost. Of the remaining 16 fetuses, one was diagnosed with significant

Twin-twin transfusion syndrome (TTTS) occurs in approximately 15% of monochorionic pregnancies. The disease is thought to result from unbalanced intertwin blood flow between the donor and the recipient twin through placental vascular anastomoses. Untreated, TTTS is associated with high perinatal mortality and morbidity.. Fetoscopic laser photocoagulation of the vascular anastomoses is currently the best treatment option for TTTS. The aim of laser surgery is to separate completely both fetal circulations by occluding all placental vascular anastomoses.. However, at the same time the fetoscopic procedure can cause injury to the amniotic membrane. This injury will last until childbirth, as the fetal membranes capability to repair is restricted. This can lead to preterm premature rupture of membranes (PPROM) and in some cases even to fetal loss.. Decreasing the diameter of fetoscopic instruments can reduce injury to the amniotic membrane. At University Hospital Halle/Saale a new ultrathin ...

Fetuses with congenital malformations can be helped by surgical intervention while still in the womb. The potential of intrauterine surgery to improve their chances of survival is described by Anke Diemert and her co-authors in the latest issue of Deutsches Ärzteblatt International. This kind of intervention is indicated only in fetuses with diseases that would lead to intrauterine death or to damage not amenable to post-natal repair.. Studies have shown a particularly high benefit of fetoscopic laser coagulation in twin-to-twin transfusion syndrome. Specialized centers can nowadays achieve survival of both twins in 70 percent and of at least one twin in 90 percent of cases. Intrauterine surgery also improves the prognosis of fetuses with spina bifida. Further fetoscopic treatments remain experimental and are not generally indicated for the time being.. This having been said, the authors view fetal surgery as a dynamically developing field and urge all affected parents to seek expert advice. ...

SAN CARLOS, Calif., Oct. 2, 2017 /PRNewswire/ - Natera (NASDAQ: NTRA), a leader in non-invasive genetic testing and the analysis of circulating cell-free DNA, today announced that the companys Panorama® non-invasive prenatal test (NIPT) is now validated to screen twin pregnancies for zygosity (identical or non-identical/fraternal) and chromosomal abnormalities.. Nateras Panorama® is the first NIPT that can determine whether twins are monozygotic (identical) or dizygotic (non-identical or fraternal) as early as nine weeks gestation.1 Accurately assessing zygosity early in twin pregnancies is important; Panorama identified monozygotic twins with ,99% sensitivity and specifi-city in validation studies.1 Monozygotic pregnancies can be at risk for complications that come from monochorionicity (a shared placenta). About 67% of monozygotic pregnancies are monochorionic pregnancies, which are at the highest risk for intrauterine growth restriction, birth defects, and twin-twin transfusion syndrome ...

TY - JOUR. T1 - Probabilistic visual and electromagnetic data fusion for robust drift-free sequential mosaicking. T2 - application to fetoscopy. AU - Tella-Amo, Marcel. AU - Peter, Loic. AU - Shakir, Dzhoshkun I. AU - Deprest, Jan. AU - Stoyanov, Danail. AU - Iglesias, Juan Eugenio. AU - Vercauteren, Tom. AU - Ourselin, Sebastien. PY - 2018/4/1. Y1 - 2018/4/1. N2 - The most effective treatment for twin-to-twin transfusion syndrome is laser photocoagulation of the shared vascular anastomoses in the placenta. Vascular connections are extremely challenging to locate due to their caliber and the reduced field-of-view of the fetoscope. Therefore, mosaicking techniques are beneficial to expand the scene, facilitate navigation, and allow vessel photocoagulation decision-making. Local vision-based mosaicking algorithms inherently drift over time due to the use of pairwise transformations. We propose the use of an electromagnetic tracker (EMT) sensor mounted at the tip of the fetoscope to obtain camera ...

Results: After exclusion of 10 noninformative pregnancies, perinatal, double, and any survival rates were 61%, 44%, and 77%, respectively. When an anastomosis was detected at each of the 3 time points, perinatal and double survival rates were higher than when one was not (at first treatment, perinatal survival 83% versus 53%, respectively, P = .003; double survival 78% versus 33%, P , .001). Perinatal and double survival (P ,= .01) were poorer with more advanced stage, but any survival rates were not influenced by stage or anastomosis detection. Multiple logistic regression demonstrated that anastomosis detection at treatment increased the chance of perinatal (odds ratio [OR] 5.1, 95% confidence interval [CI] 1.6, 15.9) and double survival (OR 19.3, 95% CI 2.7, 138), independently of stage. For stages I-III at treatment, anastomosis detection predicted better perinatal (100% versus 63%, 100% versus 59%, and 83% versus 44%, respectively) and double survival rates (100% versus 52%, 100% versus ...

SAN REMO, Italy (VN) - Colombian rider Carlos Quintero will spend the night in an Italian hospital after suffering a concussion, but he is not facing life-threatening injuries in the wake of a nasty fall in Milan-San Remo.. For a few moments Saturday afternoon it looked like cycling was facing another worst-case scenario when the Colombia-Coldeportes rider crashed heavily on the descent of Le Mànie. Television images of doctors hurriedly treating the Coldeportes rider brought back the horrible images of last years Giro dItalia, when Wouter Weylandt died during a similar high-speed fall.. There was no official word from the team, but race officials confirmed that Quintero suffered a concussion and momentarily lost consciousness in the wake of his crash.. He was later transported to a hospital where a CT scan ruled out any serious brain injury. X-rays revealed a fracture to his left cheekbone and shoulder blade and a contusion to his left lung. Doctors are keeping him in the hospital overnight ...

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Causes of microchimerism can stem from the trade of cells between the mother and her fetus during pregnancy. For instance, in one study that explored microchimerism in females who had male children, found that 63% of the females tested (57 in total) had male DNA present in their brain.. Another cause of microchimerism is twin-to-twin transfer. Twin-to-twin transfer happens in the womb or in utero in which the twins exchange cells. One way twins are able to exchange this genetic information is through their placenta. A placenta is an organ that nurtures a baby by giving it the necessary oxygen and nutrients. Though not all twins share the same placenta, there is a rare possibility that the placentas connect through placental anastomoses (vessel that connects the two systems) to exchange blood cells.. Lastly, blood transfusions or organ transplants can also cause microchimeras. Take for instance blood transfusions; a process in which a patient receives a donors blood. Because this is often an ...

ARLINGTON -- Astros catcher Humberto Quintero had seen enough fowl play. It was taking too long, he said. Quintero was on deck in the ninth inning of Sundays game against the Rangers when a curious bird landed near home plate for the second time in a matter of minutes. Astros batter Chris Johnson tried to shoo it away with his bat and plate umpire Mike Reilly couldnt get it to budge, either. Thats when Quintero took over, approaching the bird and gently picking it up with both hands. He placed it in a camera well at the end of the first-base dugout, drawing cheers from the crowd. We have birds in Venezuela, said Quintero, who likes to hunt and was wearing batting gloves. Why were people scared? We have a lot of birds in Venezuela. I got it and put it away. I didnt want to wait 30 minutes for the bird to go away. Johnson was impressed with Quinteros bird-handling ability. It looked like hes done that before, Johnson said. Thats not something you see every day, so I was just trying ...

This St. Patricks Day, skip the green-tinged beer and instead drink to your health with this green smoothie created by Teresa Quintero, Wilcox Memorial Hospital clinical registered dietitian.. Smoothies can be an easy way to get more fruits and vegetables into your diet, says Quintero. They can be used as a snack, or they can replace a meal if youre in a rush so you dont skip it. They can even make for excellent recovery fuel post workouts.. Quintero came up with this green smoothie as a deliciously sneaky way to pack more calories and nutrients into her 7-year-olds diet.. This green smoothie is definitely kid approved! It is an excellent source of vitamins A and C, iron, and is a good source of calcium, she says.. But be careful with your ingredients, and watch those portions!. Quintero advises using a green, leafy vegetable - such as kale, spinach or lettuce - as your base and building on with fruits, nuts, seeds and other add-ons sparingly.. A low-fat, low-sugar milk alternative, ...

Ten years ago, I was packing up my belongings to move from my parents house and away from my friends and teaching job so I could attend law school. I cant believe its been that long. Prior to going to law school, my main source of information about how law school was came from the…