Prior research on performance feedback has focused on the direct impact of performance feedback on risk taking (Lim & McCann, 2013) and paid little attention to the role of contextual factors. In particular, there are few empirical studies that examine how performance feedback and institutions interplay in risk taking of organizations. This study aims to fill this gap by investigating the role of organization-level institutional logics and state-level institutions in a microfinance industry. Institutions arise as a result of human beings continuous efforts to deal with uncertain environments (North, 1990; Scott, 1995). Thus, individual and organizational actors are affected by institutions, and different institutions can be a source of heterogeneity of organizational behavior (Peng, 2003). This suggests that the impact of performance feedback on risk taking can be affected by institutional factors. And, microfinance industry provides a good setting to investigate this issue.

TY - JOUR. T1 - IGF feedback effects on growth hormone secretion in ewes. T2 - Evidence for action at the pituitary but not the hypothalamic level. AU - Fletcher, T. P.. AU - Thomas, G. B.. AU - Dunshea, F. R.. AU - Moore, L. G.. AU - Clarke, I. J.. PY - 1995/1/1. Y1 - 1995/1/1. N2 - The putative negative feedback effects of IGF-I and IGF-II on GH secretion were tested by intracerebroventricular (icv) and intrapituitary administration to sheep. Over two consecutive days, serial jugular blood samples were taken at 10 min intervals for 6 h from ewes n = 3/group) fitted with indwelling stainless steel cannulae into the lateral or third cerebral ventricles. The sheep were injected (icv) with either vehicle or purified ovine IGF-I (2, 4 or 8 μg). IGF-I injection had no effect on plasma GH secretion. Serial blood samples were taken from a second group of nine ewes in which ovine or recombinant human (rh) IGF-I was infused (2.5 μg/h for 2 h) into the third ventricle; once again, IGF-I failed to ...

A feedback control system is disclosed for use in processing signals employed in pulse transmittance oximetry. The signals are produced in response to light transmitted through, for example, a finger at two different wavelengths. Each signal includes a slowly varying baseline component representing the relatively fixed attenuation of light produced by bone, tissue, skin, and hair. The signals also include pulsatile components representing the attenuation produced by the changing blood volume and oxygen saturation within the finger. The signals are processed by the feedback control system before being converted by an analog-to-digital (A/D) converter (72) for subsequent analysis by a microcomputer (16). The feedback control system includes a controllable offset subtractor (66), a programmable gain amplifier (68), controllable drivers (44) for the light sources (40, 42), and the microcomputer (16). The microcomputer (16) receives signals from the offset

Curry also introduces a potential paradox in her report when she emphasises natural variations. The magnitude of natural temperature variation are regulated by feedback processes and have physical causes. The climate sensitivity also involve such feedback processes. Any feedback process based on temperature will act on both natural and forced changes in the temperature. If such feedbacks result in pronounced natural temperature variations, they also imply that the climate sensitivity is high. Examples of such feedbacks include increased atmospheric humidity and reduced snow/ice cover. Processes involving clouds are more uncertain, but they too are likely to be affected by temperature (convection) and act to modify the climatic response.. Natural variations may arise from both variations in the climatic state (eg ENSO, NAO, and PDO) or from external causes, such as changes in the sun and volcanic eruptions. There are also feedbacks relevant to forced variation as well as internal variability ...

A dual feedback control system for a Class-D power circuit maximizes efficiency by controlling the magnitude and phase angle of the resonant load circuit using two separate feedback loops. The first feedback loop changes the value of a first variable capacitor in response to difference in magnitude between the actual load impedance and the desired load impedance. The second feedback loop changes the value of a second variable capacitor in response to the phase difference between the actual phase angle and the desired phase angle. In this way, the real and imaginary components of the load impedance are controlled so that the Class-D circuit is in tune, and hence efficiency is maximized, over a wide range of load impedances. The dual feedback control of the present invention may be advantageously employed in the ballast of an electrodeless HID lamp system.

By Sontag, Eduardo Veliz-Cuba, Alan; Laubenbacher, Reinhard; Jarrah, Abdul Salam ABSTRACT Feedback loops play an important role in determining the dynamics of biological networks. To study the role of negative feedback loops, this article introduces the notion of distance-to- positive-feedback which, in essence, captures the number of independent negative feedback loops in the network, a property inherent in the network topology. Through a computational study using Boolean networks, it is shown that distance-to-positive- feedback has a strong influence on network dynamics and correlates very well with the number and length of limit cycles in the phase space of the network. To be precise, it is shown that, as the number of independent negative feedback loops increases, the number (length) of limit cycles tends to decrease (increase). These conclusions are consistent with the fact that certain natural biological networks exhibit generally regular behavior and have fewer negative feedback loops ...

0038] Referring to, for example, FIG. 3C, in the exemplary embodiment, the motors 40, 42 may have suitable position feedback systems 50, 52. The position feedback systems 50, 52 may be non-invasive with respect to the isolated atmosphere in the transport chamber, as will be described below. The feedback system 50, 52 for motors 40, 42 may be generally similar to the feedback system 150, 152 shown in FIG. 6. The feedback systems 150, 152 for each rotor may be similar to each other and may generally incorporate sensors 150A, 150G, 1501 and target indexing to establish absolute and incremental rotational position, as well as radial or centered position of the rotor 140R, 142R. In alternate embodiments, the sensors 150A, 150G, 1051 may provide feedback information for any one or more of the absolute and incremental rotational position and the radial position. For example, the sensors 150A, 150G, 1501 may be electromagnetic sensors such as Hall effect sensor, or may be optical or other beam sensors. ...

PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.

Looking for online definition of feedback inhibition in the Medical Dictionary? feedback inhibition explanation free. What is feedback inhibition? Meaning of feedback inhibition medical term. What does feedback inhibition mean?

In this study, we demonstrated that there is a positive feedback regulation between gankyrin and Nrf2, which amplifies the antioxidant capability of HCC cells. Under oxidative stress, increased Nrf2 activity promotes the transcription of gankyrin and up-regulates gankyrin expression. Excess gankyrin competitively interrupted the association between Nrf2 and Keap1 and subsequently stabilized Nrf2 protein. This positive feedback regulation helps combat excessive intracellular ROS, which reduces oxidative stress-induced cell death, maintains mitochondrial stability, and further contributes to the tumorigenesis of HCC. This feedback regulation is similar to the correlation between p62/SQSTM1 and Nrf2, as Nrf2 regulates the expression of p62/SQSTM1 through ARE, and in turn p62/SQSTM1 binds to Keap1 and prevents Nrf2 degradation (Jain et al., 2010). Similar to the p62/SQSTM1 protein, the human gankyrin protein contains an ELKE motif between aa 21-24 and an ENKE motif between aa 201-204, which serves ...

Microglia, the brains resident macrophages, help to regulate brain function by removing dying neurons, pruning non-functional synapses, and producing ligands that support neuronal survival1. Here we show that microglia are also critical modulators of neuronal activity and associated behavioural responses in mice. Microglia respond to neuronal activation by suppressing neuronal activity, and ablation of microglia amplifies and synchronizes the activity of neurons, leading to seizures. Suppression of neuronal activation by microglia occurs in a highly region-specific fashion and depends on the ability of microglia to sense and catabolize extracellular ATP, which is released upon neuronal activation by neurons and astrocytes. ATP triggers the recruitment of microglial protrusions and is converted by the microglial ATP/ADP hydrolysing ectoenzyme CD39 into AMP; AMP is then converted into adenosine by CD73, which is expressed on microglia as well as other brain cells. Microglial sensing of ATP, the ensuing

The other challenge experience in McDonalds Cooperation is on the rivalry among some employees especially the servers and the Chief-chefs In line with add, the 360-degree feedback can allow the management to assess the performance of the workers and provide performance bonus to the best performers and training to those who need to improve their skills. This is perfectly in line with Carter et al., (2005) who strongly believe that the 360-degree feedback process allows implementing strategic development decision and remuneration process. The McDonalds Cooperation can also choose the 360-degree feedback process as it is a multi-rater and anonymous system and this will avoid conflicts among its staffs (Fleenor et al. 2020). One great concern regarding the system is that the management had to communicate it to all the related stakeholders. The design can also be made to facilitate the quality of its meals offered to customers.. 2.15 Decide on the areas of work and behaviour on which feedback will ...

The data described above demonstrate a local PDE feedback regulation in cardiac myocytes whereby β1AR signals activate PDE4B3 via PKA-mediated phosphorylation. PKA-activated PDE4B, in turn, reduces the local steady-state cAMP concentration in a confined subsarcolemmal domain. The functional consequences of interrupting this feedback include increased PKA-mediated phosphorylation of Cav1.2 and RyR2, which is necessary for fine-tuning of ECC, a finding consistent with the cardiac phenotype of PDE4BKO mice (Leroy et al., 2011). Functional data on intracellular Ca2+ levels and contraction rate confirm the altered cAMP/PKA signaling in PDE4BKO myocytes. These conclusions are based on measurements of βAR-induced cAMP accumulation at the plasma membrane of PDE4BKO myocytes, the effects of acute PDE4B-selective inhibition in wild-type myocytes, the β1AR-dependent activation of PDE4B and the altered PKA-mediated phosphorylation of some, but not all substrates involved in Ca2+ homeostasis and ...

An aircraft user interface haptic feedback system includes a user interface, a position sensor, a cogless motor, and a control circuit. The user interface is movable to a position. The position sensor senses the position of the user interface and supplies a user interface position signal. The cogless motor is coupled to the user interface, and receives motor drive signals. The cogless motor, in response to the motor drive signals, supplies feedback force to the user interface. The control circuit receives at least the user interface position signal and a signal representative of the motor current and is operable, in response to at least these signals, to control the motor current supplied to the cogless motor using a non-trapezoidal motor commutation scheme.

Here, a performance appraisal provides a great base to start. Notice how I used the word counsel. the strengths and weaknesses of the individuals so as to Related Article: E-learning: The New Way of Employee Training. It is the process to obtain, analyze, and record the information about the relative worth of an employee to the organization. INDIA: Technology firm cognizant uses annual performance appraisal system to assess its employees for the purpose of retaining talent and for Compensation management. How should the company decide who gets the brass rings? With frequent and meaningful feedback, an employee : To get the most out of a feedback process, invest in something more meaningful than the traditional feedback process. 4.6 Given the rapidly evolving challenges of public management, the Group felt that the present objectives of performance appraisal, especially for the All India Services, need to be widened and deepened to respond to the emerging needs of governance. It depends on the ...

0006] In the related art, the request from the mobile terminal is limited to requesting uplink bandwidth. Also, allocation of a Fast-feedback channel (e.g., CQICH) that allows quick transferring of various feedback values was received only based according to an allocation from the base station. When the base station requests feedback values upon allocation of a CQICH region to the mobile terminal, a CQICH_Enhanced_allocation Information Element (IE), a CQICH-allocation IE or if data exists, a Fast-feedback allocation sub-header is used for informing. Only the mobile terminal that received a request through such IE or sub-header then calculates the requested feedback value and reports such thereof. Accordingly, reporting a most recent downlink channel state (condition) value of the mobile terminal with a request from the base station, changing into MIMO mode for channel improvement (enhancement) in a multiple antenna system, and other such procedures cannot be requested from the mobile terminal ...

This study evaluates the addition of a quality improvement toolbox to an online audit and feedback intervention in Dutch intensive care units. The toolbox comprises for each quality indicator (e.g., percentage of patients per shift whose pain is measured) a list of potential bottlenecks in the care process (e.g., staff is unaware of the prevailing guidelines for measuring pain every shift), associated recommendations for actions to solve mentioned bottlenecks (e.g., organize an educational training session), and supporting materials to facilitate implementation of the actions (e.g., a slide show presentation discussing the importance and relevance of measuring pain every shift). Half of the participating intensive care units will only receive online feedback, while the other half will additionally gain access to the integrated toolbox to facilitate planning and executing actions ...

How children learn from positive and negative performance feedback lies at the foundation of successful learning and is therefore of great importance for educational practice. In this study, we used functional magnetic resonance imaging (fMRI) to examine the neural developmental changes related to feedback-based learning when performing a rule search and application task. Behavioral results from three age groups (8-9, 11-13, and 18-25 years of age) demonstrated that, compared with adults, 8- to 9-year-old children performed disproportionally more inaccurately after receiving negative feedback relative to positive feedback. Additionally, imaging data pointed toward a qualitative difference in how children and adults use performance feedback. That is, dorsolateral prefrontal cortex and superior parietal cortex were more active after negative feedback for adults, but after positive feedback for children (8-9 years of age). For 11- to 13-year-olds, these regions did not show differential feedback ...

Below are some key leadership principles that apply to (Subject Name)s development. Organizations that use such a 360 review process, however, can leave managers awash in a sea of data. This is important for the development of the individual being assessed. 360 degree feedback also known as multi-rater feedback is a proven method of supporting employee development that that has been growing in popularity during the past 15 years. It works by providing them with feedback from those who know their work best. 360 Degree Feedback Help your colleagues improve. This kind of feedback is intended to measure the development and progress of employees, by asking the people who work with them to provide feedback on behaviours that 360-Degree Feedback is a procedure followed by many organizations when conducting employee performance appraisals. 360 - Degree Feeback Template. What is 360 degree feedback? The number of elements per key skill/capability varies of course, so if necessary adjust the size of the ...

TY - JOUR. T1 - Altered pulsatile and coordinate secretion of pituitary hormones in aging. T2 - Evidence of feedback disruption. AU - Veldhuis, J. D.. PY - 1997. Y1 - 1997. N2 - A novel thesis is that healthy aging of neuroendocrine axes is marked by disruption of orderly patterns of hormone release (1). This can be quantified by a recently validated approximate entropy statistic applied to 24-hour hormone profiles, e.g., luteinizing hormone (LH), and growth hormone (GH). Moreover, more subtle disturbances of feedback control are indicated by decreased conditional regularity or synchrony (higher cross-approximate entropy) within coupled axes, such as ACTH-cortisol, LH-testosterone, etc. Such alterations can precede any changes in mean serum hormone concentrations, thus highlighting an impact of age on the feedback control mechanisms that coordinate the flow of signaling information within a neuroendocrine axis or network.. AB - A novel thesis is that healthy aging of neuroendocrine axes is ...

The audit and feedback process comprises one or more cycles of establishing best practice criteria, measuring current practice, feeding back findings, implementing changes, and further monitoring. This chain is only as strong as its weakest link. Feedback effects can be weakened by information-intention gaps (feedback fails to convince recipients that change is necessary), intention-behaviour gaps (intentions are not translated into action), or behaviour-impact gaps (actions do not yield the desired effect on patient care).9 The success of national audit programmes depends on local arrangements that promote action as well as measurement.10. A synthesis of 65 qualitative evaluations proposed ways of designing audit programmes to better align with local capacity, identity, and culture and to promote greater changes in clinical behaviour.11 Healthcare organisations have finite capacity, so audit programmes should be designed so that they require less work, make best use of limited local resources, ...

The neurotransmitter 5-hydroxytryptamine (5-HT, serotonin) mediates important brain functions and contributes to the pathophysiology and successful drug treatment of many common psychiatric disorders, especially depression. It is established that a key mechanism involved in the control of 5-HT neurones is feedback inhibition by presynaptic 5-HT autoreceptors, which are located on 5-HT cell bodies and nerve terminals. However, recent experiments have discovered an unexpected complexity of 5-HT neurone control, specifically in the form of postsynaptic 5-HT feedback mechanisms. These mechanisms have the physiological effects of 5-HT autoreceptors but use additional 5-HT receptor subtypes and operate through neural inputs to 5-HT neurones. A postsynaptic feedback system that excites 5-HT neurones has also been reported. This article discusses current knowledge of the pharmacology and physiology of these new found 5-HT feedback mechanisms and considers their possible contribution to depression

The neurotransmitter 5-hydroxytryptamine (5-HT, serotonin) mediates important brain functions and contributes to the pathophysiology and successful drug treatment of many common psychiatric disorders, especially depression. It is established that a key mechanism involved in the control of 5-HT neurones is feedback inhibition by presynaptic 5-HT autoreceptors, which are located on 5-HT cell bodies and nerve terminals. However, recent experiments have discovered an unexpected complexity of 5-HT neurone control, specifically in the form of postsynaptic 5-HT feedback mechanisms. These mechanisms have the physiological effects of 5-HT autoreceptors but use additional 5-HT receptor subtypes and operate through neural inputs to 5-HT neurones. A postsynaptic feedback system that excites 5-HT neurones has also been reported. This article discusses current knowledge of the pharmacology and physiology of these new found 5-HT feedback mechanisms and considers their possible contribution to depression

This study uncovered a function of the dual specificity ERK MAP kinase phosphatase, MKP3, for the specification of mesenchymal progenitors in the somite sclerotome. We showed that Mkp3 was expressed in a twin-striped pattern, which closely matched the emergence of scleraxis transcripts along the anteroposterior somite edges (Fig. 1). This pattern suggested a link between the modulation of FGF signalling by MKP3 and scleraxis expression. We demonstrated that somitic expression of Mkp3 in the dorsal sclerotome was itself dependent on active ERK MAP kinase. This implied that FGF signalling in dorsal sclerotome cells is modulated by a negative feedback loop, which involves MKP3 and ERK MAP kinase. Indeed, we found that the levels of Mkp3 transcripts detected in response to FGF beads can cycle between extensive overexpression after a short exposure to complete loss of endogenous Mkp3 message after 24 hours (Fig. 3A-C; data not shown). We showed by western blot analysis that this dynamic response ...

download feedback systems an look is a sexual tomb of all 2-categories to an geology. amp Marxism is an selected and ,000 analysis. people without a mathematicians cancer can stream el notes engagement and the form will not be all equivalent presentations little anytime as the organism is historic with the paper.

As part of our PowerVR Graphics SDK v3.2 release, were announcing a public developer support and feedback system for PowerVR Insider members.

Patient Feedback for Vein Specialists of Pittsburgh in Oakmont, PA. Doctor Valerie Drnovsek, MD & team cares about your health and your feedback! See what people are saying about us today. We are conveniently located at 333 Allegheny Ave, #200, Oakmont, PA 15139. Book an appointment online or call (412) 312-4666.

A system and method for providing tiered patient feedback for use in automated patient care is described. Physiological measures are analyzed. Each physiological measure is representative of at least one of measured and derived patient information recorded on a substantially continuous basis and was retrieved from one such patient care record to determine a patient status. Tiered feedback is provided to an individual patient responsive to the patient status.

Interactions between cells bearing oncogenic mutations and the surrounding microenvironment, and cooperation between clonally distinct cell populations, can contribute to the growth and malignancy of epithelial tumors. The genetic techniques available in Drosophila have contributed to identify important roles of the TNF-α ligand Eiger and mitogenic molecules in mediating these interactions during the early steps of tumor formation. Here we unravel the existence of a tumor-intrinsic-and microenvironment-independent-self-reinforcement mechanism that drives tumor initiation and growth in an Eiger-independent manner. This mechanism relies on cell interactions between two functionally distinct cell populations, and we present evidence that these cell populations are not necessarily genetically different. Tumor-specific and cell-autonomous activation of the tumorigenic JNK stress-activated pathway drives the expression of secreted signaling molecules and growth factors to delaminating cells, which ...

Complementation of Ah receptor deficiency in hepatoma cells: negative feedback regulation and cell cycle control by the Ah receptor

Gesture feedback techniques are discussed that provide prompt feedback to a user concerning the recognition of one or more gestures. The feedback may be employed to confirm to a user that a gesture is being correctly recognized. The feedback may alternately warn a user that a desired gesture is not being correctly recognized, thereby allowing the user to cancel the erroneous gesture before it is invoked

Background: The integration of body-worn sensors with mobile devices presents a tremendous opportunity to improve just-in-time behavioral interventions by enhancing bidirectional communication between investigators and their participants. This approach can be used to deliver supportive feedback at critical moments to optimize the attainment of health behavior goals. Objective: The goals of this systematic review were to summarize data on the content characteristics of feedback messaging used in diet and physical activity (PA) interventions and to develop a practical framework for designing just-in-time feedback for behavioral interventions. Methods: Interventions that included just-in-time feedback on PA, sedentary behavior, or dietary intake were eligible for inclusion. Feedback content and efficacy data were synthesized descriptively. Results: The review included 31 studies (15/31, 48%, targeting PA or sedentary behavior only; 13/31, 42%, targeting diet and PA; and 3/31, 10%, targeting diet only). All

Not all comments will engage learners in the feedback cycle, where learners consider suggestions and use them to improve their performance. When instructors replace content- and action-based feedback with ego-based comments, grade-focused responses, or simple corrections, this cycle can be undermined.. Ego-based comments: These comments might be praise-oriented (I enjoyed your performance) or evaluative (Good work, Needs improvement), eliciting emotional reactions but limited cognitive engagement. Such comments, even when given with positive intentions, generally do not promote learning - and in some cases shut it down (Hattie, 2012). Praise may have a role in your interaction with learners, but it helps to think of it as separate from feedback. However, positive feedback that focuses on specific things that learners are doing well and that you want them to continue doing can be helpful. Instructors sometimes use sentence stems such as Continue . . . or Keep doing . . . to focus ...

CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): thesis or use of any of the information contained in it must acknowledge this thesis as the source of the quotation or information. i For many people images are a medium preferable to text and yet, with the exception of star ratings, most formats for conventional computer mediated feedback focus on text. This thesis develops a new method of crowd feedback for designers based on images. Visual summaries are generated from a crowds feedback images chosen in response to a design. The summaries provide the designer with impressionistic and inspiring visual feedback. The thesis sets out the motivation for this new method, describes the development of perceptually organised image sets and a summarisation algorithm to implement it. Evaluation studies are reported which, through a mixed methods approach, provide evidence of the validity and potential of the new image-based feedback method. It is concluded that the visual feedback

This paper is concerned with the linear/nonlinear aeroelastic control of 2-D supersonic lifting surfaces. Its goal is to provide the feedback control mechanism enabling one to enlarge the flight envelope by increasing the flutter speed, and also to control the character, benign/catastrophic of the flutter instability boundary. Structural and aerodynamic nonlinearities are included in the aeroelastic governing equations, and linear and nonlinear feedback controls in both plunging and pitching are employed in conjunction with proportional velocity feedback controls. The attention of the paper is focused on multiple Hopf bifurcations. In particular, the jumping phenomenon found in our previous work will be further investigated to reveal the physical implications. It is found that such a jumping occurs when the system has multiple families of limit cycles bifurcating from a same set of parameter values with multiple solutions for frequencies. The case investigated in this paper is restricted to zero ...

The T-cell receptor (TCR) signalling machinery is central in determining the response of a T cell (establishing immunity or tolerance) following exposure to antigen. This process is made difficult by the narrow margin of self and non-self discrimination, and by the complexity of the genetic programmes that are induced for each outcome. Recent studies have identified novel negative feedback mechanisms that are rapidly induced by TCR engagement and that have key roles in the regulation of signal triggering and propagation. In vitro and in vivo data suggest that they are important in determining ligand discrimination by the TCR and in regulating signal output in response to antigen.

Written feedback will be given for tutorial work within a week. Written and/or oral feedback for workshops will be given either during the sessions or within a week. Written feedback will be provided on all summative practical work within 20 working days. Closed exam results with per-question breakdown are returned to the students via supervisors within 5 weeks (as per special approval by the University Teaching Committee). Outline answers are made available via the Chemistry web pages when the students receive their marks, so that they can assess their own detailed progress/achievement. The examiners reports for each question are made available to the students via the Chemistry web pages.. ...

Signaling in development is not always on or off; often, distinct intensity and duration of signaling leads to distinct outcomes. This is true for receptor tyrosine kinase (RTK) signaling in many contexts, where negative feedback often plays a role. Although such negative feedback might reduce or even turn off signaling output over time, continued signaling is often maintained for proper cell fate specification. In this issue, Sieglitz et al. identify a positive regulator of Ras-mediated RTK signaling that they name Rau. Rau is necessary to achieve specific signaling intensity for the differentiation of photoreceptors and of glia that wrap axons in the developing Drosophila eye disc. Both the negative regulator Sprouty and Rau influence signaling through the guanosine triphosphatase Ras; specifically, Rau forms a positive feedback loop important for counteracting the Sprouty negative feedback loop.. ...

Weve demonstrated the effectiveness of our protocol in a pilot study, and now were moving on to the next stage comprising a crossover clinical study with about 50 dialysis patients, says Chait, an expert on robust feedback control design. What we hope to show is that the demonstrated success with the pilot project translates to similar success with the larger study. This study is a much stronger test of the efficacy and safety of our protocol.. In dialysis patients the amount of EPO produced by the kidneys is inappropriately low for the level of anemia, and so they are treated with recombinant human EPO hormone in order to minimize the need for blood transfusions. Chait notes that current anemia management protocols for administering EPO are more or less one size fits all and fail to achieve the desired outcomes for many patients. That is where Chaits expertise comes in. By utilizing the principles of feedback control systems, his protocols enable medical personnel to personalize the EPO ...

The student feedback forms have, in essence, been a system of feedback that has been hit-and-miss with the students. On the one hand you have a system that tries to incorporate a flimsy notion of student rights whilst on the other hand you have a system that more often than not seems too distant from the student. The recent complaints directed at the feedback system, due to the delays in the publication of results, shows how certain shortcomings have limited the impact of the system at large.. Firstly it must be pointed out that with regard to the publication of results it is the lecturers who have the right of this issue. In a collective agreement made with the lecturers (which is in the process of being renegotiated), they are allowed to give in results by the end of March however truth be told this agreement is of suspect legal impact since no sanctions per se are highlighted for any breaches.. ...

In order to be successful, millennial leaders need regular, useful, and frequent feedback into their performance. Here are 5 reasons why thats so, according to one leadership consultant.

Download SPINA for free. Structure parameter inference approach for endocrine feedback control. SPINA is software for determining constant structure-parameters of endocrine feedback control systems from hormone levels obtained in vivo. The first version of this cybernetic approach allows for evualuating the functional status of the thyroid gland, i.e.

When a query is commenced, the query is resolved as a similarity search by a couple of search engines (including AltaVista, Excite, etc.). The Web assistant then collects the top n (60 for the prototype) documents returned and groups them into clusters. What differs here from the Scatter/Gather by [4] is that the feedback of relevant clusters and the documents are not only gathered for clustering again but the query is modified for better formulating the information needed.. As we mentioned earlier, relevance feedback has long been suggested as a solution for query modification. Rocchio describes an elegant approach and shows how the optimal vector space query can be derived using vector addition and subtraction given the relevant and non-relevant documents [6]. The probabilistic model proposed by Robertson and Sparck Jones shows how to adjust the individual term weight based on the distribution of the terms in relevant and non-relevant document set [5].. Now, given the cluster or concept as ...

Thalamic activity is regulated by corticothalamic feedback from layers 5B and 6. The nature of these feedback systems differs, one difference being that whereas layer 5 provides driver input, the layer 6 input is thought to be modulatory. To selectively study the importance of the layer 6 corticothalamic (L6 CT) projection, a transgenic mouse line was used in which layer 6 cells projecting to posterior medial thalamus (POm) were targeted for expression of channelrhodopsin-2 and in vivo electrophysiology recordings were done in urethane-anaesthetized mice. […]. Read More… ...

Thanks for this post, Matthew. This got me thinking a lot. For me, the difference between a tutoring session and a course is like that of a short story and a novel. In the session, I am making sure every moment and move matters. I feel the need to understand the assignment and writer as quickly as possible, make strategic choices about what to cover and how deeply, and get straight to the point. I am much more direct. I also cling to the prompt much more because I dont know if the instructor/ professor likes surprises and also because as an outside reader I feel thats one of my uses- I can usually see when something is going off track or not following directions. As a teacher, I think I spend a lot of time getting to know students and building a relationship with them. I comment mostly on ideas and logics that one might see as big picture concerns. And I deliberately write assignments to be open ended so that I am surprised. As I tutor I want the assignment and the prompt to match, in other ...

Additionally, for the majority of phosphorylation sites identified on the CD3γδζ subunits, we observed a gradual decrease in Zap-70 null/reconstituted SILAC ratios at early time points, followed by a gradual increase in Zap-70 null/reconstituted SILAC ratios at later time points (Fig. 7E2). These trends are consistent with the hypothesis of competing positive and negative feedback loops functioning at different stages of stimulation. At early time points, positive feedback mechanisms could be regulating these sites, leading to a gradual decrease in Zap-70 null/reconstituted SILAC ratios. At later time points, negative feedback mechanisms could be regulating these same sites, leading to an increase in Zap-70 null/reconstituted SILAC ratios when Zap-70 is removed (Fig. 7E1). It has previously been shown that Erk positive and SHP-1 negative feedback pathways can compete to either activate or inhibit Lck function to allow for T cells to discriminate between self and foreign ligands (47).. To ...

As I said, I agree (for arguments sake) that the positive feedback loop is essential for switching the climate-systems between cold and warm states that are relative stable (i.e. ice-ages and interglacials). However, the positive feedback loop predominates only during the transition between states. Within each relatively stable state negative feedback must predominate or else stability would not be maintained. And today we find ourselves in just such a stable, negative feedback-dominated state in which climatic stability and equilibrium are maintained dynamically by the systems intrinsic negative feedback mechanism. In this state any global warming that occurs will be arrested automatically by the dominant negative feedback mechanism so that the default equilibrium temperature of the system is maintained within relatively narrow bounds. I think this by itself explains why no-one can find the tropospheric hotspot, regardless of any problems over our techniques of scientific measurement and the ...

Performance Improvement involves analysis of current systems such as Senior Leadership, Governance, Workforce, Measurements, Work Processes, Customer/Client, and Analytics. Analysis in these operations allows the identification of opportunities for improvement to increase efficiency and increase performance. Evaluation of these areas, we provide written feedback reports, verbal consulting, or supervision of implementations. We do not tell you specifically how to do your duty, but we provide these types of feedback to stimulate team brainstorming for solutions to close performance gaps. We simply identify areas of opportunity to improve.. Strategic Sustainability & Social Responsibility Consulting provides solutions to current needs and forecasting to provide proactive action plans for future generations. This can include Diversity, Equity, and Inclusion, mitigating Environmental Waste with creative solutions, or identifying opportunities to create a sustained competitive advantage in strategic ...

The period (per) gene likely encodes a component of the Drosophila circadian clock. Circadian oscillations in the abundance of per messenger RNA and per protein (PER) are thought to arise from negative feedback control of per gene transcription by PER. A recently identified second clock locus, timeless (tim), apparently regulates entry of PER into the nucleus. Reported here are the cloning of complementary DNAs derived from the tim gene in a two-hybrid screen for PER-interacting proteins and the demonstration of a physical interaction between the tim protein (TIM) and PER in vitro. A restricted segment of TIM binds directly to a part of the PER dimerization domain PAS. PERL, a mutation that causes a temperature-sensitive lengthening of circadian period and a temperature-sensitive delay in PER nuclear entry, exhibits a temperature-sensitive defect in binding to TIM. These results suggest that the interaction between TIM and PER determines the timing of PER nuclear entry and therefore the duration ...

Manual ventilations during cardiac arrest are frequently performed outside of recommended guidelines. Real-time feedback has been shown to improve chest compression quality, but the use of feedback to guide ventilation volume and rate has not been studied. The purpose of this study was to determine whether the use of a real-time visual feedback system for ventilation volume and rate improves manual ventilation quality during simulated cardiac arrest. Teams of 2 emergency medical technicians (EMTs) performed two 8-min rounds of cardiopulmonary resuscitation (CPR) on a manikin during a simulated cardiac arrest scenario with one EMT performing ventilations while the other performed compressions. The EMTs switched roles every 2 min. During the first round of CPR, ventilation and chest compression feedback was disabled on a monitor/defibrillator. Following a 20-min rest period and a brief session to familiarize the EMTs with the feedback technology, the trial was repeated with feedback enabled. The primary

Feedback control of dynamic systems. Available online Root-locus and frequency response design techniques. Experience with feedback control and mechanical prototyping is also useful. Along the way his group has also worked substantially on single-molecule biophysics, quantum information science, and quantum materials. Design of linear feedback control systems for command-following error, stability, and dynamic response specifications. Examples from a variety of fields. #11 . If autonomous vehicles or driver assistance systems had capabilities similar to those of racecar drivers, many fatal accidents could be avoided. Examples from a variety of fields. The Stanford KLA Systems Engineering Certificate Program is a custom graduate program, designed specifically for KLA employees that offers hand-picked, interdisciplinary courses. He served as Chair of the Department of Applied Physics at Stanford from 2010-2016. ... quantum feedback control and quantum model reduction. Access study documents, get ...

The 2015 Physician Quality Reporting System (PQRS) feedback reports will be available in September 2016 for individual eligible professionals (EPs) and PQRS group practices. The PQRS feedback reports will provide the final determination on whether or not participants met the PQRS criteria for avoiding the 2017 PQRS negative payment adjustment. Detailed information about the quality data submitted by the provider is also included. The 2015 PQRS feedback reports reflect data from the Medicare Physician Fee Schedule (PFS) claims received with dates of service from January 1, 2015 - December 31, 2015 that were processed into the National Claims History (NCH) by February 26, 2016. A PQRS feedback report will be generated for each Taxpayer Identification Number/National Provider Identifier (TIN/NPI) combination that reported PQRS data or that submitted Medicare PFS claims that included denominator-eligible events but did not submit PQRS data. The feedback reports will include all measures reported by ...

The 2015 Physician Quality Reporting System (PQRS) feedback reports will be available in September 2016 for individual eligible professionals (EPs) and PQRS group practices. The PQRS feedback reports will provide the final determination on whether or not participants met the PQRS criteria for avoiding the 2017 PQRS negative payment adjustment. Detailed information about the quality data submitted by the provider is also included. The 2015 PQRS feedback reports reflect data from the Medicare Physician Fee Schedule (PFS) claims received with dates of service from January 1, 2015 - December 31, 2015 that were processed into the National Claims History (NCH) by February 26, 2016. A PQRS feedback report will be generated for each Taxpayer Identification Number/National Provider Identifier (TIN/NPI) combination that reported PQRS data or that submitted Medicare PFS claims that included denominator-eligible events but did not submit PQRS data. The feedback reports will include all measures reported by ...

Histamine receptors provide feedback inhibition for the synthesis and release of histamine from the hypothalamus, as well as inhibition of other neurotransmitters, such as acetylcholine from intestinal cholinergic nerves, and norepinephrines from the retina and cerebral cortex. Our previous results suggest that the regulation of histamine release by histamine H3 receptors changes with the progression of hypertension in Spontaneously Hypertensive Rats (SHR). Therefore, we believe that the histamine H3 receptor plays a role in the promotion and sustained development of hypertension. Analysis of saturation binding data from Spontaneously Hypertensive Rat cerebral cortex indicate that as animals aged from six to sixteen weeks the maximal number of receptor sites (Bmax) increased whereas the affinity of [3H]-N-a-methylhistamine for these sites decreased. B max was 38 + 1.58, 59.63 + 2.48, 79.17 + 5.02, and 84.41 + 3.72 fmol/mg of protein at six, nine, twelve, and sixteen weeks, respectively. High performance

1. Give feedback all year round: Thats right. Effectively managing employee performance means you should give employees ongoing feedback all year round. If other priorities start taking over your time (like howling at the moon), make sure giving employee performance feedback isnt pushed off your radar. Try booking one hour each week in your calendar to make notes on employee performance and then offer your feedback and comments back verbally or in writing. Remember to keep a journal where you make notes on any successes, incidents and challenges as they happen - so no one gets a fright when you present feedback.. 2. Hold formal performance review meetings quarterly: Best-in-class companies conduct quarterly, mini-performance review meetings. Even if your organization doesnt require quarterly reviews (full moon optional), you can still conduct them yourself. Meet with each employee and do a quick review of their goals and development plans, and give them verbal and written feedback on their ...

Control of thyroid hormone homeostasis is essential for function and development of the organism and hence for individual health. It is therefore not surprising that the thyroids function is controlled by a complex, multi-loop feedback control system.. Today, the central component of the thyrotropic feedback control system is still poorly understood on a physiological level. Therefore, in mathematical models different functional relations describing the feedback-inhibition of thyrotropin incretion by thyroid hormones have been suggested [Danziger and Elmergreen 1956, Roston 1959, Norwich and Reiter 1965, DiStefano and Stear 1968, DiStefano 1969, Saratchandran et al. 1973, Li et al. 1995, Dietrich et al. 2004, Degon et al. 2008, Jonklaas and Soldin 2008, Hörmann et al. 2010]. Most of these models fail in delivering biochemical explanations for the functional interrelations they postulate.. Nevertheless, some clinical applications of these models have been developed, although their diagnostical ...

Purpose: Feedback can enhance acute physical performance. However, its effects on physical adaptation have received little attention. Therefore, the purpose of this study was to determine the effect of feedback during a 4-wk training program on jump, sprint, and strength adaptations. Methods: A total of 28 semiprofessional male rugby union players were strength-matched into 2 groups (feedback and nonfeedback). During the 4-wk training program, the Feedback group received immediate, objective feedback on (1) mean concentric velocity during resistance training repetitions, (2) distance feedback for standing broad jumps, and (3) time for sprints. The Nonfeedback group was not provided additional information. Across the 4-wk mesocycle, subjects completed 3 strength and conditioning sessions per week. Countermovement jump, standing long jump, 10- and 20-m sprint, and 3-repetition-maximum barbell back squat and bench press were measured before and after the training intervention. Magnitude-based inferences

TY - JOUR. T1 - Effect of feedback signal on blood pressure self-regulation capability in individuals with prehypertension or stage i hypertension a randomized controlled study. AU - Wang, Mei Yeh. AU - Chang, Nen-Chung. AU - Hsieh, Ming-Hsiung. AU - Su, Chien-Tien. AU - Liu, Ju-Chi. AU - Shyu, Yuh Kae. AU - Tsai, Pei-Shan. PY - 2016. Y1 - 2016. N2 - Objectives: We aimed to determine the efficacy of an 8-week direct blood pressure (BP) biofeedback training programfor prehypertensive or stage I hypertensive patientswith a particular focus on the impact of the authenticity of feedback signals on the efficacy of BP regulation. Designs: This study has a randomized, double-blind, parallel-group design. Participants and Methods: Fifty-nine individuals with ages from 18 to 64 years and who met the criteria for the diagnosis of prehypertenion or stage 1 hypertension participated in this study. The participants were referrals from physicians or community-dwelling volunteers. No participants had taken ...

TY - JOUR. T1 - Atrial natriuretic factor modulates whole kidney tubuloglomerular feedback. AU - Margulies, K. B.. AU - Burnett, John C Jr.. PY - 1990. Y1 - 1990. N2 - Increases in sodium delivery to the distal nephron reduce glomerular filtration rate (GFR) via tubuloglomerular feedback (TGF). Central volume expansion and pharmacological concentrations of atrial natriuretic factor (ANF) are known to attenuate this response. To test the hypothesis that whole kidney TGF is attenuated by pathophysiological concentrations of ANF, hypertonic saline was given intrarenally in five dogs receiving an intravenous infusion of synthetic ANF at 20 ng·kg-1·min-1. To examine whole kidney TGF responses in heart failure, six additional dogs with acute congestive heart failure induced by rapid ventricular pacing also received intrarenal hypertonic saline. Seven sham-paced dogs served as controls. An isolated increase in circulating ANF from 26 ± 3 to 342 ± 23 pg/ml abolished the whole kidney GFR response to ...

Gaze changes involving the eyes and head are orchestrated by brainstem gaze centers found within the superior colliculus (SC), paramedian pontine reticular formation (PPRF), and medullary reticular formation (MdRF). The mesencephalic reticular formation (MRF) also plays a role in gaze. It receives a major input from the ipsilateral SC and contains cells that fire in relation to gaze changes. Moreover, it provides a feedback projection to the SC and feed-forward projections to the PPRF and MdRF. We sought to determine whether these MRF feedback and feed-forward projections originate from the same or different neuronal populations by utilizing paired fluorescent retrograde tracers in cats. Specifically, we tested: 1. whether MRF neurons that control eye movements form a single population by injecting the SC and PPRF with different tracers, and 2. whether MRF neurons that control head movements form a single population by injecting the SC and MdRF with different tracers. In neither case were double labeled

Feedback loops refer to the manner that the nervous system guides the endocrine system to control body conditions. More precisely, feedback mechanisms are responses that trigger other processes and activities. Your endocrine system controls various bodily functions including sexual development, reproduction, growth, and maintenance, metabolism, respond to external stimuli.. Regardless of the function it controls, the endocrine system follows the same pattern that includes receiving a signal, hormonal response, and reaction. Feedback loops regulate a vast majority of endocrine activities. Basically, feedback loops function like a thermostat which responds to the changes in temperature and informs the furnace when to switch on/off.. In humans, the hypothalamus acts like a thermostat of feedback systems and the endocrine glands act like the air conditioner or a heater. Hormones are either released or stop being produced in response to the messages sent by the hypothalamus.. Feedback loops can be ...

UAL has recently launched a new policy on assessment feedback time in response to student feedback on the importance of timely feedback. We are working to ensure that you receive written feedback on your summative assessment within 3 weeks of the submission date. There is a maximum turnaround time of 4 weeks, except in the case of dissertations, where feedback will be returned within a maximum of 6 weeks to allow more time for marking.. This policy is part of a number of projects UAL is running which are working towards improving the assessment experience for students and staff. For further details about the 3 week turnaround time, ask your course team or check out the Assessment website.. ...

Tubuloglomerular feedback (TGF) and connecting tubule glomerular feedback (CTGF) autoregulate nephronal afferent arteriolar resistance. In TGF, the macula densa signals the afferent arteriole to constrict when NaCl transport is enhanced by increased luminal NaCl, via sodium[[Unable to Display Character: –]]potassium-2-chloride cotransporter-2 (NKCC2). CTGF is mediated by connecting tubule sodium transport via epithelial sodium channel (ENaC) and dilates the afferent arteriole. Attenuation or resetting of TGF occurs after unilateral nephrectomy (UNX), but the mechanism behind this resetting remains unclear. This TGF resetting after UNX has been implicated in progressive glomerular damage due to sustained increase in glomerular capillary pressure. Since TGF is attenuated after UNX, we sought to test the hypothesis that CTGF is enhanced and that it contributes to TGF resetting after UNX. To test this hypothesis, we performed right side UNX in Sprague Dawley (SD) rats. 24 hours after surgery, ...

An introduction to analysis and design of feedback control systems, including classical control theory in the time and frequency domain. Modeling of physical, biological, and information systems using linear and nonlinear differential equations. Linear vs. nonlinear models, and local vs. global behavior, Input/ output response, modeling and model reduction, Stability and perfor¬mance of interconnected systems, including use of block diagrams, Bode plots, the Nyquist criterion, and Lyapunov functions. Robustness and uncertainty management in feedback systems through stochastic and deterministic methods. Basic principles of feedback and its use as a tool for altering the dynamics of systems and managing uncertainty methods. Introductory random processes, Kalman filtering, norms of signals and systems. Topics in 221B: The aim of this course is to introduce the student to the area of nonlinear control systems with a focus on systems analysis and control design. Nonlinear phenomena including ...

Description: In this research, a security architecture based on the feedback control theory has been proposed. The first loop has been designed, developed and tested. The architecture proposes a feedback model with many controllers located at different stages of network. The controller at each stage gives feedback to the one at higher level and a decision about network security is taken. The first loop implemented in this thesis detects one important anomaly of virus attack, rate of outgoing connection. Though there are other anomalies of a virus attack, rate of outgoing connection is an important one to contain the spread. Based on the feedback model, this symptom is fed back and a state model using queuing theory is developed to delay the connections and slow down the rate of outgoing connections. Upon implementation of this model, whenever an infected machine tries to make connections at a speed not considered safe, the controller kicks in and sends those connections to a delay queue. Because ...

Open Mentor is a tool to support tutors in the feedback process and addresses the following problem: that a balanced combination of socio-emotive and cognitive support is required in the feedback from teaching staff and the feedback needs to be relevant to the assigned grade. Open Mentor analyses and displays the different types of comments provided by the tutor as feedback to the students, and it then provides reflective comments to the tutor about their use of feedback. This work followed a pedagogically-driven development process, beginning by developing scenarios of use, then storyboards, and then putting in place an implementation which would follow closely the pattern of these storyboards. Open Mentor was not designed for use at institutional level, but to give teaching staff a tool that can be used in training and also later as personal support that will enable individual tutors to track their use of feedback to students. This work was developed in conjunction with Stuart Watt at Robert ...

Assignment:. Click on http://www.biologycorner.com/anatomy/chap1.html and do the Body Cavities Label 1 and the Body Cavities Label 2 Scroll down on the same page and take the Body Cavities Quiz. III Homeostasis. A. Definitions. B. Set points. 1. medical diagnosis. C. Maintenance. 1. sensors. 2. control center. 3. effectors. 4. negative feedback regulation. 5. positive feedback regulation. when we have finished covering this material, you should be able to: - distinguish between anatomy and physiology. - give an example of how structure fits function. - identify standard anatomical position and explain why it is important. - be able to draw and label the major body cavities. - locate parts of the body using directional terms, planes of section, and body cavities. - define homeostasis and give examples of it in the body - define set points and give examples in the body. - define negative feedback regulation. - explain what sensors do to maintain homeostasis. - explain what the control center ...

[email protected]. Abstract: The recent RFID-based logistics environment enables significant improvement of business efficiency. However, to support an efficient logistics processing service in the RFID-based international logistics service platform, it is required security risk analysis and security control model. In this paper, we have analyzed and figured out requirements of the security for the efficient international RFID-based logistics service. It is possible to construct own security policy for each enterprise using RBAC. The security policy includes definition of subjects, objects, permissions, roles, role hierarchy and constraints of the enterprise. And we proposed an RBAC-based security control model, reflecting security requirements in an international logistics process and constraints of the access control model have been represented as UML. We presented example scenario and implemented the prototype system for the verification of the proposed security model for international ...

It has been hypothesized that chronic inflammatory diseases such as rheumatoid arthritis (RA) may be caused by a failure of negative feedback mechanisms. This study sought to examine negative feedback mechanisms in fibroblast-like synoviocytes (FLS), one of the most abundant cell types in the joint. We hypothesized that prior exposure of healthy FLS to an inflammatory stimulus would attenuate their responses to a second inflammatory stimulus, in the same way that negative feedback mechanisms desensitize macrophages to repeated stimulation by lipopolysaccharide. We further hypothesized that such negative feedback mechanisms would be defective in FLS derived from the joints in RA. Synovial fibroblasts and dermal fibroblasts from non-inflamed joints and joints affected by RA and a fibroblast cell line from neonatal foreskin were stimulated twice with tumour necrosis factor (TNF) α or interleukin (IL)-1α, with a 24-h rest period between the two 24-h stimulations. Differences between response to the first

Many opportunistic pathogens upregulate the production of virulence factors according to their density within hosts (Williams et al. 2000). The diffusible molecules capable of relaying information about density can have diverse functions. However, microbiologists commonly assert that density-dependent increases in virulence arise because of positive feedback effects on the success in combating host immunity (de Kievit & Iglewski 2000; Williams et al. 2000), what ecologists refer to as an Allee (1931) effect. Excessive virulence at low density is hypothesized to elicit an immune response in which bacteria are unable to survive, while coordinated virulence at high density is adaptive.. Evolutionary biology theory suggests a different interpretation of this phenotypic plasticity. Increasingly, microbial virulence factors have been found to be shared social traits (public goods), imposing metabolic costs on individual cells but benefiting groups of pathogens (West & Buckling 2003). If this ...

Positive feedback loops soon reach the runaway/self-destruction stage. Concentrations of wealth and gaming-the-system are reaching just such levels.. Positive feedback loops lead to runaway scenarios. The classic example is global warming and the Arctic ice cap. As temperatures rise, the the ice melts, exposing more land or seawater. Ice reflects solar radiation, and so as it shrinks then more solar radiation is absorbed, raising temperatures more, which melts the ice faster, which then leads to more solar radiation being absorbed, and so on.. The runaway feedback loop leads to the disappearance of the Arctic ice and a much warmer planet.. Nature has multiple feedback loops, and so the solar radiation flux may be acting to reduce temperatures as the positive feedback of melting ice raises temperatures. But the point is that positive feedback is self-reinforcing and it speeds up processes as it gathers momentum.. We can see runaway feedback loops in the economy and society, not just in Nature. ...

A system is disclosed for monitoring and controlling laser cladding process by powder injection in real-time. The invention combines laser cladding technique along with automated direct feedback control to achieve a good quality clad in terms of dimensional and metallurgical characteristics. The system uses optical CCD-based image detectors (20) in the feedback system. The optical CCD-based detectors (20) along with a pattern recognition algorithm is used to determine the clad characteristics in real-time. These characteristics are clad dimensions, solidification rate, and roughness that are fed into a closed loop control system (18) to adjust the laser (12) power and table (16) velocity to produce desired clad quality.

The performance of three different feedback control systems has been studied in controlling the vibration of a rotor-bearing system. Two Different mathematical models of the rotor-bearing system have been presented. One model is developed by considering the rotor-bearing system on rigid supports and another model is developed by considering the system on flexible supports. The control techniques applied on these models are: the State variable feedback, Integral plus state variable feedback and Linear quadratic servo. The response of the deflection of the rotor has been simulated on a digital computer. The results of the simulation are presented. These control techniques have been compared on the basis of time-response specifications. The relative suitability of controllers is discussed. The effect of the flexibility of the supports, on the response of the rotor-deflection has been studied. The results obtained for different support stiffnesses are discussed.. ...

Define feedback. feedback synonyms, feedback pronunciation, feedback translation, English dictionary definition of feedback. n. 1. a. The return of a portion of the output of a process or system to the input, especially when used to maintain performance or to control a system or...

TY - JOUR. T1 - Herbivory and Stoichiometric Feedbacks to Primary Production. AU - Krumins, Jennifer Adams. AU - Krumins, Valdis. AU - Forgoston, Eric. AU - Billings, Lora. AU - van der Putten, Wim H.. N1 - 5586, TE; Data archiving: Data Archived at publisher. PY - 2015. Y1 - 2015. N2 - Established theory addresses the idea that herbivory can have positive feedbacks on nutrient flow to plants. Positive feedbacks likely emerge from a greater availability of organic carbon that primes the soil by supporting nutrient turnover through consumer and especially microbially-mediated metabolism in the detrital pool. We developed an entirely novel stoichiometric model that demonstrates the mechanism of a positive feedback. In particular, we show that sloppy or partial feeding by herbivores increases detrital carbon and nitrogen allowing for greater nitrogen mineralization and nutritive feedback to plants. The model consists of differential equations coupling flows among pools of: plants, herbivores, ...

Regenerative circuits were invented and patented in 1914[14] for the amplification and reception of very weak radio signals. Carefully controlled positive feedback around a single transistor amplifier can multiply its gain by 1,000 or more.[15] Therefore, a signal can be amplified 20,000 or even 100,000 times in one stage, that would normally have a gain of only 20 to 50. The problem with regenerative amplifiers working at these very high gains is that they easily become unstable and start to oscillate. The radio operator has to be prepared to tweak the amount of feedback fairly continuously for good reception. Modern radio receivers use the superheterodyne design, with many more amplification stages, but much more stable operation and no positive feedback.. The oscillation that can break out in a regenerative radio circuit is used in electronic oscillators. By the use of tuned circuits or a piezoelectric crystal (commonly quartz), the signal that is amplified by the positive feedback remains ...

EXAM GROUP: 15, 16. A survey of systems theory with applications from bioengineering and physiology. Analysis: modeling real systems as discrete elements; nonlinear systems, the complementary nature of time and frequency methods; feedback; stability; biological oscillations. Applications: muscle dynamics and nerve function, cardiovascular regulation. Laboratory: neural modeling; feedback control systems; properties of muscles; cardiovascular function.. Prerequisites: Applied Mathematics 21b or Mathematics 21b or equivalent ...

Response 1 of 2: Ask some trusted colleagues who have been around longer, and your career counselor, for advice on how to frame things. You are not alone in wondering how to handle reviews. And as a newbie, it isnt really rocket science, and the outcome may not vary too much. So dont stress too much.

In biological systems such as organisms, ecosystems, or the biosphere, most parameters must stay under control within a narrow range around a certain optimal level under certain environmental conditions. The deviation of the optimal value of the controlled parameter can result from the changes in internal and external environments. A change of some of the environmental conditions may also require change of that range to change for the system to function. The value of the parameter to maintain is recorded by a reception system and conveyed to a regulation module via an information channel. An example of this is insulin oscillations.. Biological systems contain many types of regulatory circuits, both positive and negative. As in other contexts, positive and negative do not imply that the feedback causes good or bad effects. A negative feedback loop is one that tends to slow down a process, whereas the positive feedback loop tends to accelerate it. The mirror neurons are part of a social feedback ...

Previous article on the integrative modelling of Parkinsons disease (PD) described a mathematical model with properties suggesting that PD pathogenesis is associated with a feedback-induced biochemical bistability. In this article, the authors show that the dynamics of the mathematical model can be extracted and distilled into an equivalent two-state feedback motif whose stability properties are controlled by multi-factorial combinations of risk factors and genetic mutations associated with PD. Based on this finding, the authors propose a principle for PD pathogenesis in the form of the switch-like transition of a bistable feedback process from healthy homeostatic levels of reactive oxygen species and the protein ?-synuclein, to an alternative disease state in which concentrations of both molecules are stable at the damagingly high-levels associated with PD. The bistability is analysed using the rate curves and steady-state response characteristics of the feedback motif. In particular, the ...

The teleost thyroid secretes L-thyroxine (T4) under the control of pituitary thyroid-stimulating hormone (TSH), regulated by predominantly inhibitory hypothalamaic neural pathways. Plasma T4 exerts negative feedback control at both pituitary and hypothalamic levels, but the set-point changes, altering plasma T4. A commonly-held view is that thyroidal status (availability of hormone to receptors) is driven by the brain-pituitary-thyroid axis. However, plasma T4 levels are often exceeded by those of 3,5,3'triiodo-L-thyronine (T3), a tissue derivative of T4 with greater receptor affinity. T3 availability is determined by a T4 outer-ring deiodinase (T4ORD) which generates T3, and by a T3 inner-ring deiodinase (T3IRD). Both enzymes are regulated peripherally, and for a given physiological state stabilize plasma T3 despite T3 or T4 challenges. Furthermore, plasma T3 can be depressed without change in plasma T4. Thus thyroidal status in teleosts may not be driven by the brain-pituitary-thyroid axis, but

Our patients are our top priority at Horizon Family Medical Group. We strive to anticipate and meet all care needs and expectations of our patients. As such, patient input and feedback are crucial to Horizon Family Medical Group as it helps us to further enhance our patients experience and provide the best care possible.. Patient feedback cards are located throughout our offices and patients can complete an Online survey on our website. We encourage patients to provide feedback and we will ensure that every patient feedback card and Online survey are reviewed and addressed. Heres what some of our patients are saying about us:. Love my experience with Horizon, all staff from receptionist to nurses and MA makes me feel like family. Who loves to go to the doctor….I DO!. Last January, I was sick and called my Horizon providers office to see if they had flu tests. I was given an appointment the following morning. I have never had such a thorough exam before. My provider was very professional ...

Video The closest point of contact between a brand and a user online is a mere click, says Nicola Farronato, Italian entrepreneur in Ireland with B-Smark. On its first birthday, the company launched a Beta version of its online service MySmark, giving users the ability to attach an emotional tag to content on [...]

Digitization makes comprehensive behaviour and consumption data available: modern vehicles, fitness wristbands, mobile phones, digital assistants, electricity meters and intelligent everyday objects are collecting more and more user data - in real time and at ever lower costs. The Chair of Information Systems, esp. Energy Efficient Systems, researches how this data can be used in everyday life to support decisions and promote desired behaviours - and thereby links the scalability of digitization with the methods of behavioural economics. An example of our work: field studies on the effect of real-time feedback on water and energy consumption in private households.. In cooperation with leading universities (ETH Zurich, National University of Singapore, University of Bonn) and international organizations (Public Utility Board Singapore, Schweizer Mobiliar Versicherung, Amphiro, PWN, Hansa) we examine the effect of feedback interventions in combination with goals, social Norms, monetary incentives ...

An optimal online feedback treatment strategy is developed for the parturient paresis of cows, based on nonlinear optimal control theory. A limitation in the development of an existing mathematical model for calcium homeostasis is addressed and the model is extended to incorporate control inputs. An optimal feedback controller is synthesized for the nonlinear system using neural networks. Though the main aim of this paper is to solve the biomedical control problem, the methodology presented in this paper is a general computational tool, which can be applied to solve a fairly general class nonlinear optimal control problems.

Absolute position feedback can be critical in robotic applications, where the robot arm position must be determined at all times, even after a loss of power. In torque motor implementations, the accuracy of the rotational encoder is often the key to the accuracy of the entire system. In many servo-robotic applications, rotary position feedback from an encoder at the motor provides sufficient positioning accuracy at the robot arm, but when applications demand higher precision, primary or secondary feedback in the form of an axis-mounted magnetic rotary encoder from Balluff could be the answer. Balluff can supply a variety of magnetic encoder rings and disks of various shapes and sizes, in incremental and absolute variations. ...

This paper presents a conceptual model that integrates multi-disciplinary findings in order to develop a more comprehensive view of the etiology and development of schizophrenia. The model attempts to compile the various variables that may place an individual at risk for or protect them from developing schizophrenia. The model utilizes a feedback loop, in order to depict a continuous state of interaction with all relevant variables. Consistent with this continuous interaction, the model assumes schizophrenia can develop through multiple pathways. This is critical in order to understand a disorder like schizophrenia that does not have a pure genetic, neurological, or environmental source of causation. A literature review is presented to expand on research covering each of the relevant variables of the model, including genetic, neurological, and environmental. This model is intended as a conceptual tool to develop testable hypotheses for the purpose of developing potentially valuable solutions, such as

A cloud-based (SaaS) edition of the Oxygen Feedback commenting platform that is hosted, set up, and maintained on Oxygen servers. The Cloud edition features a very fast start-up process, no software installation is required, and you always have access to the latest version of the software. The Oxygen Feedback commenting platform provides a simple and efficient way for your community to interact and offer feedback. Its modern, stylish appearance looks great on any website, it is very easy to configure and integrate, and it includes a user-friendly interface and numerous useful features for both Commenters and Administrators. It is specialized for technical documentation and can easily be integrated with Oxygen XML Editor/Author to make it more efficient for content authors to manage comments and react to community feedback. ...

Robustness and adaptability are central to the functioning of biological systems, from gene networks to animal societies. Yet the mechanisms by which living organisms achieve both stability to perturbations and sensitivity to input are poorly understood. Here, we present an integrated study of a living architecture in which army ants interconnect their bodies to span gaps. We demonstrate that these self-assembled bridges are a highly effective means of maintaining traffic flow over unpredictable terrain. The individual-level rules responsible depend only on locally-estimated traffic intensity and the number of neighbours to which ants are attached within the structure. We employ a parameterized computational model to reveal that bridges are tuned to be maximally stable in the face of regular, periodic fluctuations in traffic. However analysis of the model also suggests that interactions among ants give rise to feedback processes that result in bridges being highly responsive to sudden interruptions in

If you are considering Orthodontic Treatment, we thought you might like to read some feedback from David* who underwent treatment with Jason Hart at Bath Spa Dentistry recently.. What motivated you to undertake your treatment at Bath Spa Dentistry?. I chose to undertake treatment because I had misaligned top teeth, specifically the front ones which had been damaged in a sporting accident. Also, my bottom teeth were extremely crowded. So much so, that as well as being overlapped, they were not level.. I chose Bath Spa Dentistry (local to where I live) after the initial consultation with Jay Hart who explained clearly, exactly how he could have my teeth sorted out using fixed braces and he showed me several photo examples of past patients.. Thinking back to before you had your treatment, how did your dental problem make you feel?. I am aware that prior to treatment my smile was perhaps somewhat suppressed, knowing that from observing photos of myself, that my teeth were nowhere near ...

Co-taught with Dr. T. Delworth) This class provides overview of the broad factors that determine our current climate, as well as past and future climates. The focus is on Earths energy and water cycles, the processes determining the principal atmospheric and ocean circulation features, climate feedback processes, and dominant modes of variability ...

Scientists from the universities of Exeter and Helsinki and the Finnish Meteorological Institute examined natural processes caused by frost and snow which take place in these zones.. Their findings suggest that - even with optimistic estimates of future carbon emissions - areas covered by periglacial zones will reduce dramatically by 2050, and they will almost disappear by 2100.. This would have a major impact on landscapes and biodiversity, and could trigger climate feedbacks - processes that can amplify or diminish the effects of climate change.. The results suggest that profound changes can be expected in current periglacial zones regardless of climate change mitigation policies, said Dr Juha Aalto, of the University of Helsinki and the Finnish Meteorological Institute.. Unfortunately, it seems that many of the frost-driven processes we studied are already at the margin of the climate in which they can exist.. The scientists studied four processes which take place in periglacial ...