AGENT HAVING NEUROTROPHIC FACTOR-LIKE ACTIVITY - The present invention provides a pharmaceutical agent having high safety and a neurotrophic factor-like activity, which contains, as an active ingredient, any one compound included in fatty acids each having 8 carbon atoms (C8) or having 10 carbon atoms (C10) to 12 carbon atoms (C12) or fatty acid esters thereof, such as 3,7-dimethyloctanoic acid ethyl ester, geranic acid ethyl ester, and the like, each of which has 8 carbon atoms (C8), decanoic acid methyl ester, trans-2-decenoic acid, trans-2-decenoic acid methyl ester, trans-2-decenoic acid ethyl ester, trans-2-decenoic acid-2-decenyl ester, trans-2-decenoic acid cyclohexyl ester, trans-2-decenoic acid isopropyl ester, trans-3-decenoic acid methyl ester, trans-9-decenoic acid methyl ester, and the like, each of which has 10 carbon atoms (C10), trans-10-undecenoic acid methyl ester, trans-10-undecenoic acid ethyl ester, and the like, each of which has 11 carbon atoms (C11), and dodecanoic acid, ...
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This study reported a simple and inexpensive method for determination of 10-hydroxy-2-decenoic acid (10-HDA) and free amino acids in different royal jelly based dietary supplement samples using a purpose-made dual-channeled capillary electrophoresis (CE) system with capacitively coupled contactless conductivity detection (C4D). The objective of the work is to propose a tool for food / quality cont...
5&6-Decenoic Acid(Milk Lactone), CAS 72881-27-7, Aromatic Chemical, , China, Manufacturer, China supplier of Aromatic Chemicals, Essential Oils, Food Additive, Food Ingredients, Forest Chemicals, Natural Aromatic Chemicals, and more.
Otherwise known as massoi lactone-the key flavor component of massoi bark oil-5-hydroxy 2-decenoic acid delta lactone is known for adding a creamy note in more than just dairy flavors.
The appropriate pattern of macronutrient distribution for dietary protocols aimed at treating or preventing obesity and its associated cardiovascular diseases is still a controversial topic of discussion. Recommendations considering a specific percentage or range for monounsaturated fatty acids (MUF …
Peterson, D.G. 2005. Recovery and purification of 10-oxo-trans-8-decenoic acid enzymatically produced using ... and 10-oxo-trans-8-decenoic acid using a crude homogenate of Agaricus bisporus: Reaction Scale Up. J. ... 10-oxo-trans-8-decenoic acid using a mushroom homogenate. Optimization of the reaction, part I: kinetic factors. Process .... ...
This study suggests that dietary fat intake is associated with the risk for allergic sensitisation and disease manifestation, with somewhat different findings in males and females. In both males and females, there were indications for an increased risk with a high intake of omega‐6 and a low intake of omega‐3 fatty acids. In females, total fat and high monounsaturated fatty acids intake were also associated with an increased risk of suffering atopic manifestations. This data adds to the limited epidemiological evidence available on associations between dietary habits and atopic disease prevalence. Most of the published studies were conducted in children, and dietary intake was assessed using simple food item lists, not always well validated. Previous epidemiological studies in Germany used data on the preferred type of spreadable fats on bread as a surrogate for the type of consumed fat and without specific fatty acid determination. The authors did not consider that the total fat intake from ...
Monounsaturated fat is an essential nutrient in a heart-healthy diet. Find foods at your grocery store that will add more monounsaturated fats to your meals.
Monounsaturated fatty acids (MUFA) have been viewed as either beneficial or neutral with respect to health; however, recent evidence suggests that MUFA may be associated with obesity and cardiovascular disease. Sex differences in MUFA composition have been reported in both rats and humans that may be mediated by sex hormones. Therefore, differences in fatty acid and enzyme expression were examined in male and female rats. HepG2 cells treated with 17β-estradiol, progesterone and testosterone (0, 10, 30 and 100 nM), and ovariectomized female rats with hormone implants (sham, no treatment, estradiol, progesterone, and estradiol plus progesterone) examined the role of sex hormones in MUFA metabolism. MUFA concentrations were determined by gas chromatography. The mRNA and protein expression of stearoyl-CoA desaturase and elongase 6, key enzymes involved in MUFA biosynthesis, were measured by real-time PCR and immunoblotting, respectively. Elongase 6 protein expression was higher in females as ...
In the present meta-analysis, comparison of the top versus the bottom third of combined MUFA subgroups (MUFA, olive oil, oleic acid, and MUFA:SFA) was associated with reduced risk of all-cause mortality (11%), cardiovascular mortality (12%), combined cardiovascular events (9%), and stroke (17%). In the ensuing subgroup analyses, this significant correlation could only be observed between higher intakes of olive oil and reduced risk of all-cause mortality, cardiovascular events, and stroke, respectively. In contrast, monounsaturated fatty acids of mixed animal and plant origin did not result in any significant effects with respect to these outcome parameters. Thus, it seems possible that olive oil represents the crucial factor of influence for the protective health effects observed in the primary analysis. However, one has to keep in mind the limitations of the present systematic review and meta-analysis summarized at the end of this section, especially the fact that the specific sources of MUFA ...
(HealthDay)-Monounsaturated fatty acids (MUFAs) may reduce inflammation and improve insulin sensitivity in adipose tissue, according to research published online Jan. 27 in Diabetes.
New Report On Global Monounsaturated Fatty Acid Market Status and Future Forecast 2015-2024 added to Orbisresearch.com store which has 142 pages and available for purchase at US $ 4500.
1575-72-0 - UMYDNZXEHYSVFY-UHFFFAOYSA-N - 2-Propyl-4-pentenoic acid - Similar structures search, synonyms, formulas, resource links, and other chemical information.
chemBlink provides information about CAS # 90600-20-7, (S)-N-Boc-allylglycine, (S)-N-tert-Butoxycarbonyl-2-amino-4-pentenoic acid, molecular formula: C10H17NO4.
Since well before the days of snake oil peddlers and modern Western medicine, people have been on the hunt for the next "fountain of youth," a formula that will either keep us young or extend our lifespans. And, while there have been a number of promising discoveries, theres no pill that you can take to make you live forever (yet). But a recent study published in Nature presents a compelling argument that monounsaturated fatty acids may be the next item on the list of promising discoveries.. Monounsaturated fats are simply fats that contain just one double bond among the links between their carbon atoms. These types of fats naturally occur in several types of food products, including red meat, dairy, nuts, and high-fat plant foods such as olives and avocado. In fact, many plant and nut oils have a high monounsaturated fat content.. Over the last several decades, monounsaturated fats have occasionally been the focus of health and diet studies. For example, the Mediterranean diet, which is ...
To examine the mechanisms by which platelet aggregability was altered by treatment with fluvastatin, we measured PDNO and oxidative stress. Only fluvastatin but not colestimide increased PDNO and decreased oxidative stress (increased GSH, increased GSH/GSSG, and decreased nitrotyrosine). Again, these antioxidative stress effects were not related to cholesterol levels, indicating pleiotropic effects of fluvastatin. In support of the present findings, we recently reported in rats that statin upregulated eNOS mRNA, augmented PDNO release, and attenuated platelet activation.29 Taken together, the present findings indicate that fluvastatin improves the imbalance of intracellular redox state, resulting in improvements of bioactivity of PDNO, and that this improvement in PDNO bioactivity may be responsible for the decreased platelet aggregation observed following fluvastatin treatment.. Interestingly, treatment with fluvastatin altered platelet function to a level better than in normocholesterolemic ...
Our study showed for the first time the effect of the long term consumption of four dietary models, providing different quantity and quality of dietary lipids, on the whole proteome of peripheral blood mononuclear cells (PBMC) from patients with MetS. In this study, we analyzed separately the changes induced in the nuclear and cytoplasmic proteome after the long-term consumption of a high saturated fatty acid diet (HSFA), a high monounsaturated fatty acids-rich diet (HMUFA), a low-fat high carbohydrates diet (LFHCC) and a low-fat high carbohydrates diet supplemented with n-3 fatty acids (LFHCC n-3).. The proteins responding to the quantity and quality of dietary lipids identified in our study showed that dietary lipids regulate different biomechanisms directly involved in the etiology of MetS. This idea is supported by the relationship found between MetS parameters, mainly in changes in the TAG and glucose levels and several changes in the proteome. Long-term consumption of an HSFA diet leads to ...
The report generally describes palmitoleic acid, examines its uses, production methods, patents. PALMITOLEIC ACID market situation is overviewed; palmitoleic
Monounsaturated Fat Functions Monounsaturated fat tends to lower LDL cholesterol (the "bad" cholesterol) Monounsaturated Fat SourcesMonounsaturated
Royal Jelly 365 Capsules are easy to swallow softgel capsules and the only natural source of 10H2DA (10-Hydroxy-2-decenoic acid).
Yes, you read that right-canola oil is a cooking oil that you can use for frying without jeopardizing your heart health. But first, what is canola and what are the benefits we derive from it?. Canola is extracted from grapeseed, which is low in uric acid and glucosinolates. Thus, while canola oil is characterized by a low level of harmful saturated fatty acids, it has substantial amounts of monounsaturated fatty acids, which are touted to have positive effects on cardiovascular health through the regulation of plasma lipids and proteins. In 2006, the US Food and Drug Administration declared that "eating about 1½ tablespoons (19 grams) of canola oil daily may reduce the risk of coronary heart disease due to its unsaturated fat content.". Research published in Nutrition Reviews further reveals five studies that compared canola-based diets with typical Western diets and found evidence that canola was able to reduce total cholesterol levels by an average of 12.2%. This cholesterol-reducing action ...
Cationic lipid DNA complexes based on DOTAP (1,2-dioleoyl-3-(trimethyammonium) propane) and mixtures of DOTAP and cholesterol (DC) have been previously optimized for transfection efficiency in the absence of serum and used as a non-viral gene delivery system. To determine whether DOTAP and DC lipid DNA complexes could be obtained with increased transfection effciency in the presence of high serum concentrations, the composition of the complexes was varied systematically and a total of 162 different complexes were analyzed for transfection efficiency in the presence and absence of high serum concentrations. Increasing the ratio of DOTAP or DC to DNA led to a dose dependent enhancement of transfection efficiency in the presence of high serum concentrations up to a ratio of approximately 128 nmol lipid/μg DNA. Transfection efficiency could be further increased for all ratios of DOTAP and DC to DNA by addition of the DNA condensing agent protamine sulfate (PS). For DOTAP DNA complexes with ratios of ≤ 32
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The scope of this study was to characterize the effect of a moderate, isocaloric fat diet either supplemented by MUFAs (canola oil) or by SFAs (milk fat), which only differed in fat quality but not quantity. Measures of glucose homeostasis, lipid metabolism, brain activity, and sleep architecture were performed to judge the value of fat quality in the mouse brain, and this was verified in humans.. We previously showed that feeding of mice with high-fat diet resulted in impaired insulin action in the brain (16). Because of the extreme fat load rich in SFAs, the current study focused on the impact of a moderate, isocaloric fat enrichment with diets that differ in their MUFA and SFA content. Of note, both fat-enriched diets contained less polyunsaturated fatty acids compared with chow and further studies are needed to address this issue in more detail.. We show that slightly elevated, chronic SFA intake impaired peripheral glucose metabolism and led to insulin resistance, which was also verified in ...
Canola oil is rich in fat-soluble vitamins, beta-carotene, and omega 3 and 6 fatty acids, helps in slowing down the digestion process, and provides warmth to the body. It has lower fat content and a good amount of unsaturated fats. It is the third-largest consumed oil crop and second-most preferred feedstock. Traditionally, Canadian plant breeders obtained canola oil from rapeseed. However, currently, the oil is obtained by crushing canola seeds. The Canadian industry adopted the name Canola in 1978, which was derived from CANadian Oil, Low Acid. Publishers analysts forecast the global canola oil market to grow at a CAGR of 5.48% during the period 2017-2021.. Complete Report Available at http://www.reportsweb.com/global-canola-oil-market-2017-2021 .. Covered in this report The report covers the present scenario and the growth prospects of the global canola oil market for 2017-2021. To calculate the market size, the report considers the product applications, end-user segmentation, and geographic ...
Being diagnosed with Diabetes can be frightening; in just a few minutes, your whole world changes. Youre handed so much information and processing it can be
Whilst there is a large body of evidence looking at the design of cationic liposomes as transfection agents, correlates of formulation to function remain elusive. In this research, we investigate if lipid packaging can give further insights into transfection efficacy. DNA lipoplexes composed of 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) or 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (DSPE) in combination with 1,2-dioleoyl-3-trimethylammonium-propane (DOTAP) or 1,2-stearoyl-3-trimethylammonium-propane (DSTAP) were prepared by the lipid hydration method. Each of the formulations was prepared by hydration in dH2O or phosphate buffer saline (PBS) to investigate the effect of buffer salts on lipoplex physicochemical characteristics and in vitro transfection. In addition, Langmuir monolayer studies were performed to investigate any possible correlation between lipid packaging and liposome attributes. Using PBS, rather than dH2O, to prepare the lipoplexes increased the size of vesicles in most of
Palmitic acid (PA), impairs insulin sensitivity in skeletal muscle, and replacing PA in the diet with oleic acid (OA), a monounsaturated fatty acid (FA), may be beneficial. The first objective of this project is to understand the effects on lipid metabolism and skeletal muscle lipid composition, insulin signaling, and inflammatory signaling of two common variations in FA composition of the diet: (1) The typical intake of North America where PA and OA are present in equal proportions (HI PA diet). (2) The Mediterranean FA composition in which PA is much lower and OA much higher (HI OA diet). PA may induce insulin resistance in skeletal muscle cells via its accumulation in lipids within muscle cells and via activation of inflammatory signaling. The second objective of this project is to assess the hypothesis that a high intake of PA will down-regulate its own one-carbon (initial) oxidation, leading to increased inflammatory signaling and decreased insulin signaling. However, there is literature ...
Another Group of Friendly Fats that Can Support Good Health When Consumed in Moderation. For 40 years, medical experts have been telling us that fat in a dietary evil.
If your cholesterol is too high, you may be wondering what to eat in order to lower it without drugs. Heres a list of 10 foods that lower cholesterol naturally.Cinnamon Just half a teaspoon per day of cinnamon has been found to lower LDL cholesterol.Almonds Almonds are a great way to lower cholesterol. This is due to their high monounsaturated fat content as well as ... Continue Reading ...
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies. ...
Exposure of human islets cultivated at 5.5 mmol/l glucose to 0.1, 0.25, and 0.5 mmol/l palmitic acid for 4 days induced a 2.12-, 2.51-, and 3.59-fold increase, respectively, of the number of TUNEL-positive β-cells (Fig. 1). Exposure to 33.3 mmol/l glucose induced a 3.3-fold increase of the number of TUNEL-positive β-cells relative to islets at 5.5 mmol/l glucose (Fig. 1B). Glucose (33.3 mmol/l) together with 0.1-0.5 mmol/l palmitic acid had no additive effect (Fig. 1B). In contrast, the monounsaturated palmitoleic acid (0.5 mmol/l) and oleic acid (0.1-0.5 mmol/l) did not induce β-cell DNA fragmentation (Fig. 1). When added together with the corresponding concentration of palmitic acid, 0.5 mmol/l palmitoleic acid and 0.25-0.5 mmol/l oleic acid reduced the palmitic acid effect on β-cell death (Fig. 1B). Furthermore, 0.5 mmol/l palmitoleic acid and 0.25-0.5 mmol/l oleic acid prevented the β-cells from 33.3 mmol/l glucose-induced apoptosis and limited the apoptotic effect of both, increased ...
Fluvastatin is used together with diet, weight loss, and exercise to reduce the risk of heart attack and stroke and to decrease the chance that heart surgery will be needed in people who have heart disease or who are at risk of developing heart disease. Fluvastatin is also used to decrease the amount of fatty substances such as low-density lipoprotein (LDL) cholesterol (bad cholesterol) and triglycerides in the blood and to increase the amount of high-density lipoprotein (HDL) cholesterol (good cholesterol) in the blood. Fluvastatin may also be used to decrease the amount of cholesterol and other fatty substances in the blood in children and teenagers 10 to 17 years of age who have familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally). Fluvastatin is in a class of medications called HMG-CoA reductase inhibitors (statins). It works by slowing the production of cholesterol in the body to decrease the amount of ...
... is in a group of drugs called HMG CoA reductase inhibitors, or statins. Fluvastatin reduces levels of bad cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of good cholesterol (high-density lipoprotein, or HDL). Fluvastatin is used to treat high...
Canola oil is one of the most widely consumed vegetable oils, yet little is known about its health effects. Now, a study in Scientific Reports by Lewis Katz School of Medicine at Temple University researchers associates canola oil consumption in the diet with worsened memory, worsened learning ability and weight gain in mice which model Alzheimers disease. Its the first study to suggest that canola oil is more harmful than healthful for the brain.
The study, the first randomized controlled trial of purified palmitoleic acid supplementation in humans, took place at the Xyrion Medical Institute,in Ponce, Puerto Rico, headed by Michael F. Roizen, MD and Adam M. Bernstein, MD, from the Wellness Institute of the Cleveland Clinic. The 30-day parallel, double-blinded, randomized, placebo-controlled study used 60 healthy participants, supplemented with 220.5 mg of a branded purified omega-7 palmitoleic acid supplement daily over the study period. C-reactive protein(CRP), and serum lipid levels were taken at baseline and at the 30-day mark, with all participants asked to maintain their normal diets for the course of the study.. The studys results were uniformly positive for the palmitoleic acid group, with 44%, 15%, and 8% reductions in CRP, triglyceride, and LDL cholesterol respectively, along with a 5% increase in HDL cholesterol over the control group. Roizen and Bernstein noted in their conclusions that "these findings build on a growing body ...
Introduction: Fatty acids (FAs) are principal constituents of dietary fat. Epidemiological studies show that high fat diets (HFDs) regulate pancreatic cancer. However, the nature of the regulation may depend on the major types of dietary FAs namely saturated fatty acids (SFAs), monounsaturated fatty acids (MUFAs) and n6- and n3 polyunsaturated fatty acids (n6PUFAs and n3PUFAs). We undertook the present study to investigate effects of these FAs on pancreatic cancer. Methods: We made four HFDs that all had 15% fat and 4 kcal/g. Fat contents in these HFDs were derived from cocoa butter, olive oil, soybean oil and flaxseed oil, respectively. These fat origins were chosen because in each of them more than 50% of total FAs are from a single FA type. Consequently, four HFDs were enriched with SFAs, MUFAs, n6PUFAs and n3PUFAs, respectively. Two normal-fat (4%-5%) diets were used as controls. One of them was iso-caloric to HFDs (IsoC control) and the other was normal chow (NC control, 3 kcal/g). The 6 ...
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Olive oil is rich in oleic acid, a common monounsaturated fatty acid. Numerous studies indicate that monounsaturated fat is about as effective as...
Monounsaturated fats are healthy fats found in olive oil, avocados and some nuts. This article discusses the potential health benefits of these fats.
Is Canola Oil Bad for You?. Many plant and vegetable oils we use for cooking are named directly by their source and canola oil is no different. How canola was produced is a little novel. Canola is a plant which is essentially a ...
We have all heard bad things about fats over the years. In fact, fats are a vital part of your diet because they provide the most concentrated form of energy that is available from food. There are different kinds of fats, some that are healthy and some that are not, especially for some people with HIV. Make sure your diet contains the healthy type of fats.. Unsaturated fats, monounsaturated fatty acids and omega-3 fatty acids are all good for heart health. These types of fats come mainly from plant sources. They can be found in olive oil, canola oil, flax oil, nuts and avocados. Salmon is also an excellent source of omega-3 fatty acids.. Saturated and trans fats are not good for the health of your heart because they can clog your veins and arteries and raise your risk of heart disease. Avoiding saturated and trans fats is important for some people with HIV because some anti-HIV drugs may increase their levels of cholesterol.. Saturated fats are found mainly in animal fats and dairy fats and ...
Before starting fluvastatin, or at the same time as starting to take it, you should be placed on a cholesterol-lowering diet. If appropriate, your health care professionals will discuss an individualized program of weight control and physical exercise with you.. The recommended adult dose of fluvastatin ranges from 20 mg to 80 mg daily. Up to 60 mg daily can be taken as one dose in the evening or at bedtime. The 80 mg daily dose can be taken as one 40 mg capsule twice daily, with or after meals, or as one extended-release capsule taken once daily in the evening.. Fluvastatin may be taken with or without food, but it should be taken consistently with regard to food (always with food or always without food).. Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your ...
Canola is the healthiest vegetable oil available today. The Canola Council recently asked leading scientists from across Canada and the U.S. how we could build on this advantage through canola oil research. Here are the priorities they identified:. Heart Health. Canolas low saturated fat content has long been accepted as beneficial for heart health, and it has an established positive effect on blood lipids.. However, interest in blood lipids as a risk factor is falling rapidly. There is increasing interest in markers of inflammation, oxidation and endothelial function. The effect of canola oil on these emerging risk factors is most likely favourable, but is not well documented.. Preliminary clinical trials are underway, but further research is needed - particularly regarding canola oils positive effects on inflammation and vascular function.. Diabetes. Inflammation was recently implicated as a significant cofactor in development of type 2 diabetes. Canola oil may improve patients ability to ...
Consuming canola oil can cause fatty deposits to accumulated on hearts, thyroids, adrenal glands and kidneys. Canola oil has been shown to inhibit enzyme function, according to Natural News. It also...
In a separate procedure that measures the ability of compounds to specifically inhibit cancer cell division, canola meal extracts were shown to specifically inhibit an enzyme called Topoisomerase-1. This enzyme is active in dividing cancer cells.. Ms Hussain said, "This suggests canola meal contains compounds that may one day be used to treat some cancers.". Through the study, Ms Hussain from the School of Biomedical Sciences at CSU in Wagga Wagga is combining her interests in plants and improving human health. "I am hoping my research can solve a number of problems," Ms Hussain said.. "The dramatic increase in canola production in Australia has provided an opportunity to develop new high-value products from canola meal, which is normally a low value by-product of canola crushing.. "If we can increase the value of the canola meal, it will make canola an even more profitable crop for farmers.. "If we can discover compounds that can improve human health, we may end up growing canola primarily for ...
What is the recommended daily intake of polyunsaturated and monounsaturated fat for a female of 22 years that is involved in low activity? Answered by Dr. Mary Callahan: Fat RDAs: Ther really isnt a recommended allowance of fat since fat ...
Scientists in Pennsylvania say the untested claims of canola oils healthfulness arent based on facts and that its better to stick with olive oil.
Canola oil is also versatile: it has a neutral taste, light texture and a medium-high smoke point, so it works well for sautéing and baking. (An oils smoke point is the temperature at which it begins to smoke. When it does, disease-causing carcinogens and free radicals are released, so you never want to heat your oil to that point ...