Looking for online definition of farmer's lung in the Medical Dictionary? farmer's lung explanation free. What is farmer's lung? Meaning of farmer's lung medical term. What does farmer's lung mean?
Understanding the effects of intensive agricultural land use activities on water resources is essential for natural resource management and environmental improvement. In this paper, multi-scale nested watersheds were delineated and the relationships between two representative water quality indexes and agricultural land use intensity were assessed and quantified for the year 2000 using multi-scale regression analysis. The results show that the log-transformed nitrate-nitrogen (NO3-N) index exhibited a relationship with chemical fertilizer input intensity and several natural factors, including soil loss, rainfall and sunlight at the first order watershed scale, while permanganate index (CODMn) had a positive relationship with another two input intensities of pesticides and agricultural plastic mulch and organic manure at the fifth order watershed scale. The first order watershed and the fifth order watershed were considered as the watershed adaptive response units for NO3-N and CODMn, respectively. The
Hyaluronate and type III procollagen peptide concentrations in bronchoalveolar lavage fluid as markers of disease activity in farmer's lung. Bjermer, Leif; Engstrom-Laurent, Anna; Lundgren, Rune; Rosenhall, Leif; Hallgren, Roger // British Medical Journal (Clinical Research Edition);10/3/1987, Vol. 295 Issue 6602, p803 Investigates the hyaluronate and type III procollagen peptide concentrations in bronchoalveolar lavage fluid as markers of disease activity of farmer's lung. Prominence of impaired diffusion capacity; Decline of lavage fluid concentrations; Increase in risk of fibrotic lung disease. ...
Effect of Ape1/Ref-1 on injury caused by stereotactic ablative radiotherapy in the treatment of early stage non-small cell lung cancer, Lei Han, Renzhi Yu, Xin Ni, Zenglei Zhang
1. Olaussen KA, Dunant A, Fouret P, Brambilla E, Andre F, Haddad V. et al. DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy. The New England journal of medicine. 2006;355:983-91 2. Hubner RA, Riley RD, Billingham LJ, Popat S. Excision repair cross-complementation group 1 (ERCC1) status and lung cancer outcomes: a meta-analysis of published studies and recommendations. PLoS One. 2011;6:e25164 3. Allingham-Hawkins D, Lea A, Levine S. ERCC1 Expression Analysis to Guide Therapy in Non-Small Cell Lung Cancer. PLoS Curr. 2010;2:RRN1202 4. Azuma K, Komohara Y, Sasada T, Terazaki Y, Ikeda J, Hoshino T. et al. Excision repair cross-complementation group 1 predicts progression-free and overall survival in non-small cell lung cancer patients treated with platinum-based chemotherapy. Cancer Sci. 2007;98:1336-43 5. Malottki K, Popat S, Deeks JJ, Riley RD, Nicholson AG, Billingham L. Problems of variable biomarker evaluation in stratified medicine research-A case ...
Veracyte Announces New Clinical Data Showing First-Ever Noninvasive Nasal Swab Test Can Enable Early Lung Cancer Detection and Diagnosis Data presented today at CHEST 2019 Annual Meeting; Company plans to begin making test available in early 2021 Conference call and webcast today at 5:00 p.m. ET to review third quarter 2019 Financial results and the new nasal swab test data Veracyte, Inc. (Nasdaq: VCYT) today announced preliminary clinical data showing that the company's noninvasive nasal swab test - the first of its kind - can enable early lung cancer detection and diagnosis so that more lives can be saved. The new findings specifically show that the novel genomic test can accurately classify lung cancer risk in patients with lung nodules so that these patients can obtain the prompt diagnosis and potential treatment they need or may be monitored noninvasively. The findings will be presented today at the annual meeting of the American College of Chest Physicians® (CHEST) in New Orleans. "Early ...
Recent reports suggest that minor overt hemoptysis may accompany sequestration of large amounts of iron in the lung leading to hypochromic anemia in patients with idiopathic pulmonary hemosiderosis. Linear profile scanning was used to quantify intrapulmonary hemorrhage in such a patient, a 44-year-old menopausal housewife with dyspnea and hemoptysis. A diagnosis of idiopathic pulmonary hemosiderosis was confirmed by streaks of blood and hemosiderin-laden macrophages in the sputum, intense hemosiderosis in a lung biopsy specimen, iron deficiency anemia, and ephemeral pulmonary infiltrates on chest X ray. The patient was in remission during hospitalization. After discharge, hemoptysis and dyspnea recurred, and studies ...
TY - JOUR. T1 - Phase 1 Study of Accelerated Hypofractionated Radiation Therapy With Concurrent Chemotherapy for Stage III Non-Small Cell Lung Cancer. T2 - CALGB 31102 (Alliance). AU - Urbanic, James J.. AU - Wang, Xiaofei. AU - Bogart, Jeffrey A.. AU - Stinchcombe, Thomas E.. AU - Hodgson, Lydia. AU - Schild, Steven E.. AU - Bazhenova, Lyudmila. AU - Hahn, Olwen. AU - Salgia, Ravi. AU - Vokes, Everett E.. PY - 2018/1/1. Y1 - 2018/1/1. N2 - Purpose: To investigate the safety of accelerated hypofractionated radiation therapy (AHRT) with concurrent chemotherapy (CT) for inoperable stage III non-small cell lung cancer (NSCLC). Patients and Methods: The primary objectives were to define the maximally tolerable course of accelerated radiation therapy and to describe toxicities of therapy. Total radiation therapy remained at 60 Gy. The number of once-daily fractions in each successive cohort was reduced as follows: cohort 1, 60 Gy in 27 fractions; cohort 2, 60 Gy in 24 fractions; cohort 3, 60 Gy in 22 ...
Agriculture is one of the economic sectors that affect climate change contributing to greenhouse gas emissions directly and indirectly. There is a trend of agricultural greenhouse gas emissions reduction, but any practice in this direction should not affect negatively farm productivity and economics because this would limit its implementation, due to the high global food and feed demand and the competitive environment in this sector. Precision agriculture practices using high-tech equipment has the ability to reduce agricultural inputs by site-specific applications, as it better target inputs to spatial and temporal needs of the fields, which can result in lower greenhouse gas emissions. Precision agriculture can also have a positive impact on farm productivity and economics, as it provides higher or equal yields with lower production cost than conventional practices. In this work, precision agriculture technologies that have the potential to mitigate greenhouse gas emissions are presented providing a
Title:Comparison of Rat and Human Pulmonary Metabolism Using Precision-cut Lung Slices (PCLS). VOLUME: 13 ISSUE: 1. Author(s):Yildiz Yilmaz*, Gareth Williams, Markus Walles, Nenad Manevski, Stephan Krähenbühl and Gian Camenisch. Affiliation:Pharmacokinetic Sciences, Novartis Institutes for Biomedical Research, Basel, Pharmacokinetic Sciences, Novartis Institutes for Biomedical Research, Basel, Pharmacokinetic Sciences, Novartis Institutes for Biomedical Research, Basel, Pharmacokinetic Sciences, Novartis Institutes for Biomedical Research, Basel, Clinical Pharmacology and Toxicology, University Hospital, Basel, Pharmacokinetic Sciences, Novartis Institutes for Biomedical Research, Basel. Keywords:Precision-cut lung slices (PCLS), rat lung metabolism, human lung metabolism, rat and human pulmonary metabolism activity, pulmonary disposition of phase I and phase II drugs, dynamic organ culture system, AFQ056.. Abstract:. Background: Although the liver is the primary organ of drug metabolism, the ...
Hemosiderosis (AmE) or haemosiderosis (BrE) is a form of iron overload disorder resulting in the accumulation of hemosiderin. Types include: Transfusion hemosiderosis Idiopathic pulmonary hemosiderosis Transfusional diabetes Hemosiderin deposition in the lungs is often seen after diffuse alveolar hemorrhage, which occurs in diseases such as Goodpasture's syndrome, granulomatosis with polyangiitis, and idiopathic pulmonary hemosiderosis. Mitral stenosis can also lead to pulmonary hemosiderosis. Hemosiderin collects throughout the body in hemochromatosis. Hemosiderin deposition in the liver is a common feature of hemochromatosis and is the cause of liver failure in the disease. Selective iron deposition in the beta cells of pancreatic islets leads to diabetes due to distribution of transferrin receptor on the beta cells of islets and in the skin leads to hyperpigmentation. Hemosiderin deposition in the brain is seen after bleeds from any source, including chronic subdural hemorrhage, cerebral ...
0000002520 00000 n Restrictive lung diseases are a heterogeneous group of conditions characterized by a restrictive pattern on spirometry and confirmed by a reduction in total lung volume. 0000044299 00000 n xref 0000054386 00000 n 0000027524 00000 n 0000042951 00000 n Restrictive lung diseases are characterized by reduced lung volumes, either because of an alteration in lung parenchyma or because of a disease of the pleura, chest wall, or neuromuscular apparatus. Ё��X�q��Al�t��L}b#�c8�o���$C ZS'{U4O��I�+^/΄,o����i'{L�.-_P���=�y>wj�0 U~2;q�j,J�9��y�������02�D��/p,�öH>ి���wU� 0000028555 00000 n 0000028239 00000 n 0000044933 00000 n Restrictive lung disease most often results from a condition causing stiffness in the lungs themselves. interest in evaluating PR for patients with restrictive lung diseases. 0000001036 00000 n Both chronic obstructive pulmonary disease (COPD) and restrictive lung diseases ...
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TY - JOUR. T1 - Diffuse alveolar hemorrhage due to antibasement membrane antibody disease appearing with a polyglandular autoimmune syndrome. AU - Moss, M.. AU - Neff, T. A.. AU - Colby, T. V.. AU - Schwarz, M. I.. AU - Zamora, M. R.. PY - 1994. Y1 - 1994. N2 - We describe a patient with type 3-C polyglandular autoimmune syndrome who presented with diffuse alveolar hemorrhage and normal renal function. The diagnosis of antibasement membrane antibody disease was established by immunofluorescent staining of transbronchial biopsy specimens. We suggest the incorporation of antibasement membrane antibody disease into the spectrum of diseases that define the polyglandular autoimmune syndromes.. AB - We describe a patient with type 3-C polyglandular autoimmune syndrome who presented with diffuse alveolar hemorrhage and normal renal function. The diagnosis of antibasement membrane antibody disease was established by immunofluorescent staining of transbronchial biopsy specimens. We suggest the ...
TY - JOUR. T1 - Bilateral stony lung. T2 - Pulmonary alveolar microlithiasis. AU - Chandra, Subhash. AU - Mohan, Anant. AU - Guleria, Randeep. AU - Das, Prasenjit. AU - Sarkar, Chitra. PY - 2009/5/8. Y1 - 2009/5/8. N2 - A 40-year-old male paddy field worker was referred for exertional shortness of breath and non-productive cough for 4 years. He had been treated for pulmonary tuberculosis twice. Chest radiograph showed extensive bilateral nodular opacities (sandstorm-like) in the middle and lower lobe. Pulmonary function tests revealed a restrictive ventilatory defect. High resolution CT showed widespread nodular infiltration with crazy paving appearance and interrupted black pleura sign. This was confirmed as pulmonary alveolar microlithiasis (PAM) by trans-bronchial lung biopsy, which showed normal respiratory lining epithelium with dilated alveolar spaces containing many calcific bodies, some of which showed concentric calcification. The possibilities of silicosis (due to exposure to husk) and ...
Looking for online definition of pulmonary agenesis in the Medical Dictionary? pulmonary agenesis explanation free. What is pulmonary agenesis? Meaning of pulmonary agenesis medical term. What does pulmonary agenesis mean?
Large cell neuroendocrine carcinoma in the salivary glands is rare. We report a second case of large cell neuroendocrine carcinoma of the submandibular gland diagnosed at autopsy, and a review of the literature. A 68-year-old Japanese man was referred to our hospital for thorough investigation of swelling on the right side of his neck. Fine-needle aspiration cytology of the cervical mass suggested poorly differentiated metastatic carcinoma. The primary tumor could not be detected by several examinations. One month after admission, he died of cancer. An autopsy was performed, and it revealed a tumor of the right submandibular gland. The histopathological diagnosis was large cell neuroendocrine carcinoma of the submandibular gland. To the best of our knowledge, only eight cases of large cell neuroendocrine carcinoma in the salivary glands, including our case, have been reported. This report indicates total biopsy and immunohistochemistry are necessary for diagnosing large cell neuroendocrine carcinoma
TY - JOUR. T1 - Association of CYP19A1 polymorphisms with risks for atypical adenomatous hyperplasia and bronchioloalveolar carcinoma in the lungs. AU - Kohno, Takashi. AU - Kakinuma, Ryutaro. AU - Iwasaki, Motoki. AU - Yamaji, Taiki. AU - Kunitoh, Hideo. AU - Suzuki, Kenji. AU - Shimada, Yoko. AU - Shiraishi, Kouya. AU - Kasuga, Yoshio. AU - Hamada, Gerson Shigeaki. AU - Furuta, Koh. AU - Tsuta, Koji. AU - Sakamoto, Hiromi. AU - Kuchiba, Aya. AU - Yamamoto, Seiichiro. AU - Kanai, Yae. AU - Tsugane, Shoichiro. AU - Yokota, Jun. PY - 2010/8/5. Y1 - 2010/8/5. N2 - Estrogen has been indicated to play an etiological role in the development of lung adenocarcinoma (ADC), particularly bronchioloalveolar carcinoma (BAC), a type of ADC that develops from a benign adenomatous lesion, atypical adenomatous hyperplasia (AAH). Polymorphisms in the CYP19A1 gene cause interindividual differences in estrogen levels. Here, 13 CYP19A1 singlenucleotide polymorphisms (SNPs) were examined for associations with lung ...
Hypersensitivity pneumonitis may also be caused by fungi or bacteria in humidifiers, heating systems, and air conditioners found in homes and offices. Exposure to certain chemicals, such as isocyanates or acid anhydrides, can also lead to hypersensitivity pneumonitis.. Examples of hypersensitivity pneumonitis include:. Bird fancier's lung: This is the most common type of hypersensitivity pneumonitis. It is caused by repeated or intense exposure to proteins found in the feathers or droppings of many species of birds.. Farmer's lung: This type of hypersensitivity pneumonitis is caused by exposure to dust from moldy hay, straw, and grain. ...
In order to make this discovery, they conducted the experiment in three steps. First, they injected the lung protein alone inside frog eggs to measure its function. Second, they injected both the M2 protein from H1N1 virus and the lung protein inside frog eggs and found that the H1N1 virus M2 protein caused the lung protein function to decrease significantly. By means of molecular biology techniques, scientists isolated the segment of the H1N1 virus M2 protein responsible for the damage to the lung protein and were able to demonstrate that without this segment, the H1N1 virus was unable to damage the lung protein. Third, an intact, full H1N1 virus M2 protein and the lung protein were then re-injected into frog eggs along with antioxidant drugs. This also prevented H1N1 virus M2 protein from damaging the lung protein. When these experiments were repeated using human lung cells, the results were exactly the same ...
TY - JOUR. T1 - Pirfenidone alleviates lung ischemia-reperfusion injury in a rat model. AU - Saito, Masao. AU - Chen-Yoshikawa, Toyofumi F.. AU - Suetsugu, Kimitaka. AU - Okabe, Ryo. AU - Takahagi, Akihiro. AU - Masuda, Satohiro. AU - Date, Hiroshi. PY - 2019/7. Y1 - 2019/7. N2 - Objective: Lung ischemia-reperfusion injury is among the complications seen after lung transplantation, resulting in morbidity and mortality. Pirfenidone, an antifibrotic agent for the treatment of idiopathic pulmonary fibrosis, is reported to have cytoprotective properties in various disease models. The purpose of this study was to investigate the effect of pirfenidone on lung ischemia-reperfusion injury. Methods: Male Lewis rats (260-290 g) were divided into 3 groups: sham group (n = 5), warm ischemia (WI) group (n = 10), and WI plus pirfenidone (WI+PFD) group (n = 10). The sham group underwent 210 minutes of perfusion without ischemia. The WI and WI+PFD groups underwent 90 minutes of warm ischemia and 120 minutes of ...
TY - JOUR. T1 - Detection of latent tuberculosis infection among migrant farmworkers along the US-Mexico border. AU - Oren, E.. AU - Fiero, M. H.. AU - Barrett, E.. AU - Anderson, B.. AU - Nuñez, M.. AU - Gonzalez-Salazar, F.. PY - 2016/11/3. Y1 - 2016/11/3. N2 - Background: Migrant farmworkers are among the highest-risk populations for latent TB infection (LTBI) in the United States with numerous barriers to healthcare access and increased vulnerability to infectious diseases. LTBI is usually diagnosed on the border using the tuberculin skin test (TST). QuantiFERON-TB Gold In-Tube (QFT-GIT) also measures immune response against specific Mycobacterium tuberculosis antigens. The objective of this study is to assess the comparability of TST and QFT-GIT to detect LTBI among migrant farmworkers on the border, as well as to examine the effects of various demographic and clinical factors on test positivity. Methods: Participants were recruited using mobile clinics on the San Luis US-Mexico border and ...
Looking for online definition of Perfusion lung scan in the Medical Dictionary? Perfusion lung scan explanation free. What is Perfusion lung scan? Meaning of Perfusion lung scan medical term. What does Perfusion lung scan mean?
adult respiratory distress syndrome definition. Explain adult respiratory distress syndrome. What is adult respiratory distress syndrome? adult respiratory distress syndrome meaning. adult respiratory distress syndrome sense. adult respiratory distress syndrome FAQ. adult respiratory distress syndrome synonyms.
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ABSTRACT Human food chain toxicity, soil fertility and agricultural output have been shown to be influenced by application of various types of fertilizers. This research studied the influence of multiple fertilizer application on soil quality and plant heavy metal accumulation, proximate and phytochemical compositions. The different fertilizer samples used were NlSPlSKlS (CFI), N20PIOKIO (CF2), N27P13PI3 (CF3), pig manure (AMI) and chicken manure (AM2). Plant species used were Telfairia occidental is and Talinum triangulare. The experiment had four treatments and each treatment had 0.0, 2.0 and 4.0glkg soil. The seeds of the vegetables were planted and allowed to grow for a period of 12 weeks. The first sets of the experimental pots were left for a latent period of 12 weeks after the first harvest for second fertilizer application. The heavy metal composition of the different fertilizers and control soil as well as the plant species were studied using Atomic Absorption Spectrophotometry (AAS). ...
BackgroundMechanical ventilation causes ventilator-induced lung injury in animals and humans. Mitogen-activated protein kinases have been implicated in ventilator-induced lung injury though their functional significance remains incomplete. We characterize the role of p38 mitogen-activated protein kinase/mitogen activated protein kinase kinase-3 and c-Jun-NH2-terminal kinase-1 in ventilator-induced lung injury and investigate novel independent mechanisms contributing to lung injury during mechanical ventilation.Methodology and Principle FindingsC57/BL6 wild-type mice and mice genetically deleted for mitogen-activated protein kinase kinase-3 (mkk-3−/−) or c-Jun-NH2-terminal kinase-1 (jnk1−/−) were ventilated, and lung injury parameters were assessed. We demonstrate that mkk3−/− or jnk1−/− mice displayed significantly reduced inflammatory lung injury and apoptosis relative to wild-type mice. Since jnk1−/− mice were highly resistant to ventilator-induced lung injury, we performed
TY - JOUR. T1 - Ventilator-associated lung injury decreases lung ability to clear edema in rats. AU - Lecuona, E.. AU - Saldías, F.. AU - Comellas, A.. AU - Ridge, K.. AU - Guerrero, C.. AU - Sznajder, J. I.. N1 - Copyright: Copyright 2017 Elsevier B.V., All rights reserved.. PY - 1999. Y1 - 1999. N2 - Ventilator-associated lung injury (VALI) is caused by high tidal volume (VT) excursions producing microvascular leakage and pulmonary edema. However, the effects of VALI on lung edema clearance and alveolar epithelial cells' Na,K-ATPase function have not been elucidated. We studied lung edema clearance in the isolated-perfused rat lung model after ventilation for 25, 40, and 60 min with high VT (peak airway opening pressure [Paul of approximately 35 cm H2O) and compared them with low VT ventilation (Pao ~ 8 cm H2O), moderate VT ventilation (Pao ~ 20 cm H2O), and nonventilated rats. Lung edema clearance in control rats was 0.50 ± 0.02 ml/h and decreased after 40 and 60 min of high VT to 0.26 ± ...
In order to investigate the effect of using different nitrogen fertilizer with reclaimed water irrigation on the emissions of soil greenhouse gases (CO2 and N2O), plot experiments were conducted using clean water and reclaimed water combined with different nitrogen fertilizer (urea, ammonium sulfate, slow release fertilizer) for irrigation. No significant differences in CO2 and N2O emission flux was observed between the treatments irrigated with clean water and ones with reclaimed water. The soil CO2 emission flux had no significant relationship with the application of nitrogen fertilizer, whereas the soil emission flux increased significantly as applied with nitrogen fertilizer. The N2O emission flux reached its maximum in 2-5 days after irrigation.
Acinar cell carcinoma of lung|Adenocarcinoma of lung|Adenocarcinoma of lung (disorder)|Adenocarcinoma of lung, stage I|Adenocarcinoma of lung, stage I (finding)|Adenocarcinoma of lung, stage II|Adenocarcinoma of lung, stage II (finding)|Adenocarcinoma of lung, stage III|Adenocarcinoma of lung, stage III (finding)|Adenocarcinoma of lung, stage IV|Adenocarcinoma of lung, stage IV (finding)|Adenoid cystic carcinoma of lung|Adenosquamous carcinoma of lung|Alveolar cell carcinoma|BC - Bronchogenic carcinoma|Basaloid squamous cell carcinoma of lung|Bronchial carcinoma|Bronchiolar adenocarcinoma|Bronchiolar carcinoma|Bronchioloalveolar carcinoma|Bronchioloalveolar carcinoma (disorder)|Bronchioloalveolar carcinoma - disorder|Bronchoalveolar cancer|Bronchogenic carcinoma|CA - Cancer of bronchus|CA - Carcinoma of bronchus|CA - Lung cancer|Cancer of bronchus|Carcinoma of bronchus|Carcinoma of lung|Carcinoma of lung parenchyma|Carcinoma of lung parenchyma (disorder)|Carcinosarcoma of lung|Clear cell squamous cell
This study aimed to evaluate the effect of stereotactic ablative radiotherapy (SABR) after incomplete transcatheter arterial chemoembolization (TACE) in hepatocellular carcinoma (HCC) patients. The study enrolled 178 HCC patients initially treated with TACE between 2006 and 2011. Patients were included if they had Barcelona Clinic Liver Cancer stage 0 or A, ≤3 nodules with a total sum of longest diameter ≤10 cm, Child-Turcotte-Pugh score of ≤7, no major vessel invasion, and no extra-hepatic metastases. Twenty-four patients achieved a complete response to TACE (group 1). Among those with incomplete response, 47 patients received other curative treatments (group 2), 37 received SABR (group 3), and 70 received non-curative treatments (group 4). The 2-year overall survival (OS) rates for groups 1, 2, 3, and 4 were 88 %, 81 %, 73 %, and 54 %, respectively. The corresponding 5-year OS rates were 50 %, 58 %, 53 %, and 28 %, respectively. Patients treated with SABR after incomplete TACE had similar
Agricultural Research & Technology: Open Access Journal is a dynamic journal for publishing research reports, short communications, Critical Reviews in Agricultural Economics and Farm Management, Agronomy, Forestry, Animal Science, Food Technology, etc. The goal of the open access journalsis to publish articles on new and emerging fields and concepts for providing future directions to promote agricultural research globally. It is a unique open access journal covering all the disciplines of crop sciences, animal sciences, fishery sciences, forestry sciences and natural resources management sciences, to stimulate interest in inter-disciplinary research. This open access journal will catalyze policy development on issues impacting rational agricultural growth and development globally. It also publishes open access books.
Govindan, R, Page, N, Morgensztern, D. "Changing epidemiology of small-cell lung cancer in the United States over the last 30 years: analysis of the surveillance, epidemiologic, and end result database". J Clin Oncol. vol. 24. 2006. pp. 4539. Garfinkel, L. "Trends in cigarette smoking in the United States". Prev Med. vol. 26. 1997. pp. 447. Sculier, JP, Evans, WK, Feld, R. "Superior vena caval obstruction syndrome in small cell lung cancer". Cancer. vol. 57. 1986. pp. 847. Higgins, GA, Shields, TW, Keehn, RJ. "The solitary pulmonary nodule. Ten-year follow-up of veterans administration-armed forces cooperative study". Arch Surg. vol. 110. 1975. pp. 570. Johnson, DH, Hainsworth, JD, Greco, FA. "Pancoast's syndrome and small cell lung cancer". Chest. vol. 82. 1982. pp. 602. Osterlind, K, Andersen, PK. "Prognostic factors in small cell lung cancer: multivariate model based on 778 patients treated with chemotherapy with and without irradiation". Cancer Res. vol. 46. 1986. pp. 4189. Darnell, RB, ...
Background: Cytokine gene polymorphism could predispose to different susceptibility to occupational dust exposure.. Aim:We aimed to assess cytokine gene polymorphism contribution to occupational lung diseases development and management.. Materials and methods: Study included 240 patients (pts) with occupational lung diseases (pneumoconiosis, occupational chronic bronchitis, occupational COPD), mean age 569 years old. 60 comparable healthy volunteers with occupational hazards were enrolled. The participants of the study were genotyped on the candidate genes (TNF-α, EPHX1, CAT, IL-1, IL-6) by real time PCR technique.. Results: Allele A of TNF-α gene in G(-308)A position: incidence in pts with occupational lung diseases 44,8% (number of heterozygotes prevailed), incidence in control group 24,5% (wild GG type was more frequent)(χ=6,49; p=0,011).Heterozygotes in G (-308)A position are the risk group of the occupational lung diseases development (sensitivity of the marker 89%, specificity -53%, ...
Amylase An enzyme that is found in saliva and pancreatic secretions (see pancreas). Amylase helps the body to digest dietary starch, breaking it down into smaller components, such as the sugars glucose and maltose. Amsler chart A diagnostic tool used by ophthalmologists to detect changes in the retina, particularly those changes that indicate macular degeneration. A typical Amsler chart consists of a grid of black lines on a white background. In an individual with retinal changes, the lines may appear distorted. CAUSES Alveolitis is commonly caused by an allergic reaction to inhaled dust of animal or plant origin, as in farmer's lung (caused by spores from mouldy hay), bagassosis (caused by spores from mouldy sugar-cane residue), and pigeon fancier's lung (caused by particles from bird droppings). This type of alveolitis is known as extrinsic allergic alveolitis. alprostadil A prostaglandin drug used to minimize the effects of congenital (present from birth) heart defects in newborn babies prior ...
TY - GEN. T1 - The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 (Iressa) suppresses proliferation and invasion of human oral squamous carcinoma cells via p53 independent and MMP, uPAR dependent mechanism. AU - Eun, Ju Lee. AU - Jin, Ha Whang. AU - Nam, Kyeong Jeon. AU - Kim, Jin. PY - 2007/1. Y1 - 2007/1. N2 - Oral squamous cell carcinomas (OSCCs) are characterized by a marked propensity for local invasion and dissemination to cervical lymph nodes. Overexpression of the epidermal growth factor receptor (EGFR) and high levels of certain matrix metalloproteinases (MMPs) have been implicated in the development of squamous cell carcinoma of oral cancer. ZD1839 (Iressa) is a quinazoline derivative that selectively inhibits the EGFR tyrosine kinase activity and is clinically used for cancer patients. This article attempted to determine the mechanisms underlying the effects of ZD1839 on the cellular level, and to characterize the effects of ZD1839 with regard to human OSCC cell ...
Objective: To investigate the timing and complications of lung transplantation for the treatment of connective tissue disease-associated interstitial lung disease (CTD-ILD). Method: The clinical data of connective tissue-associated disease lung transplantation recipients from September, 2015 to February, 2017 were collected. Results: 11 patients with CTD-ILD were evaluated by lung transplantation and were treated with lung transplantation. Including 2 cases dermatomyositis/polymyositis and interstitial lung disease (PM/DM-ILD), 4 cases rheumatoid arthritis and interstitial lung disease (RA-ILD), 4 cases of primary Sjgren's syndrome and interstitial lung disease (pSS-ILD), 1 case of systemic sclerosis and interstitial lung disease (SSc-ILD ...
Inadequate ventilator settings may cause overwhelming inflammatory responses associated with ventilator-induced lung injury (VILI) in patients with acute respiratory distress syndrome (ARDS). Here, we examined potential benefits of glutamine (GLN) on a two-hit model for VILI after acid aspiration-induced lung injury in rats. Rats were intratracheally challenged with hydrochloric acid as a first hit to induce lung inflammation, then randomly received intravenous GLN or lactated Ringer's solution (vehicle control) thirty min before different ventilator strategies. Rats were then randomized to receive mechanical ventilation as a second hit with a high tidal volume (TV) of 15 mL/kg and zero positive end-expiratory pressure (PEEP) or a low TV of 6 mL/kg with PEEP of 5 cm H2O. We evaluated lung oxygenation, inflammation, mechanics, and histology. After ventilator use for 4 h, high TV resulted in greater lung injury physiologic and biologic indices. Compared with vehicle treated rats, GLN administration
Pseudomonas aeruginosa lung infections are a major cause of death in cystic fibrosis and hospitalized patients. Treating these infections is becoming difficult due to the emergence of conventional antimicrobial multiresistance. While monosaccharides have proved beneficial against such bacterial lung infection, the design of several multivalent glycosylated macromolecules has been shown to be also beneficial on biofilm dispersion. In this study, calix[4]arene-based glycoclusters functionalized with galactosides or fucosides have been synthesized. The characterization of their inhibitory properties on Pseudomonas aeruginosa aggregation, biofilm formation, adhesion on epithelial cells, and destruction of alveolar tissues were performed. The antiadhesive properties of the designed glycoclusters were demonstrated through several in vitro bioassays. An in vivo mouse model of lung infection provided an almost complete protection against Pseudomonas aeruginosa with the designed glycoclusters.. ...
Background Secondary pulmonary hemorrhage increases the risk of mortality in patients with antineutrophil cytoplasmic antibody-associated vasculitis (AAV); plasma exchange therapy may improve outcomes in these patients. We conducted a retrospective cohort study to investigate the effect of plasma exchange therapy on short-term prognoses in patients with pulmonary hemorrhage secondary to AAV. Methods This study utilized the Diagnosis Procedure Combination database, which is a nationwide inpatient database in Japan. We checked the abstract data and medical actions and identified the patients with pulmonary hemorrhage secondary to AAV who required proactive treatment between 2009 and 2014. To compare the in-hospital mortality, we performed propensity score matching between the plasma exchange and non-plasma exchange groups at a ratio of 1:1. Results Of the 52,932 patients with AAV, 940 developed pulmonary hemorrhage as a complication. A total of 249 patients from 194 hospitals were eligible for the
In the second part of this respiratory health special report, Bernard Garbe looks at how serial peak expiratory flow can be used to identify occupational asthma.. The first part of the report explores the 2010 BOHRF Occupational Asthma Guidance on sensitiser-induced occupational asthma.. In occupational health, lung disease is the most common form of disease encountered after skin problems. Occupational lung diseases include byssinosis (typically cotton dust), allergic rhinitis, farmer's lung, asbestosis, pneumoconiosis (most commonly coal dust), silicosis and chronic obstructive pulmonary disease (COPD). While COPD has the greatest mortality rate, occupational asthma (OA) has by far the greater incidence. OA, by definition, is a lung disease caused by occupational exposures and is the cause of about 15% of adult-onset asthma. Occupational asthma often results in skilled and experienced people having to end their careers, in many cases without a confirmed diagnosis. In nearly half the diagnosed ...
TY - JOUR. T1 - Mapping the human pulmonary surfactant-associated protein B gene (SFTP3) to chromosome 2p12→p11.2. AU - Vamvakopoulos, N. C.. AU - Modi, W. S.. AU - Floros, J.. N1 - Copyright: Copyright 2015 Elsevier B.V., All rights reserved.. PY - 1995. Y1 - 1995. N2 - Pulmonary surfactant, a lipoprotein complex is essential for normal lung function. The non-serum surfactant-associated proteins, SP-A, SP-B, and SP-C, play important roles in the biology of pulmonary surfactant. We have mapped the human SP-B gene (SFTP3) to chromosome 2, band 2p12→p11.2 by fluorescent in situ hybridization.. AB - Pulmonary surfactant, a lipoprotein complex is essential for normal lung function. The non-serum surfactant-associated proteins, SP-A, SP-B, and SP-C, play important roles in the biology of pulmonary surfactant. We have mapped the human SP-B gene (SFTP3) to chromosome 2, band 2p12→p11.2 by fluorescent in situ hybridization.. UR - ...
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Interstitial lung disease (ILD) is an umbrella term for disorders involving scarring or inflammation of the tissue surrounding the air sacs in the lungs. Since many patients with ILD get worse over time, getting a diagnosis and beginning treatment as soon as possible is important.. Doctors at Temple's Interstitial Lung Disease Program see patients with all types of ILD, including idiopathic pulmonary fibrosis (IPF), sarcoidosis, acute interstitial pneumonitis (AIP), bleomycin-induced pneumonitis (BIP), scleroderma-related lung disease, other connective-tissue disease associated ILDs (CT-ILD), hypersensitivity pneumonitis (HP), and others.. The team at Temple use a multi-disciplinary approach to diagnose and treat ILD. Using this approach, the ILD team is often able to diagnose patients without the need for a lung biopsy. Instead, Temple's multi-disciplinary committee uses non-invasive, high-resolution scans to diagnose most patients. When a lung biopsy is necessary, Temple's ILD physicians offer ...
The role of irrigation water in disseminating Erwinia amylovora is not fully recognized, and the survival of the bacterium in natural water has not been carefully investigated. This risk has been underestimated, since it is generally considered that E. amylovora survives only for a short period in water and its isolation from natural water samples has not been reported. The main goal of this study has been to clarify whether E. amylovora could survive under nutrient starvation conditions usually found in aquatic environments and if it is nonculturable on solid media when recovered from sterile natural water. Infectivity of E. amylovora cells in water was evaluated by using immature pear fruits. Total and viable cell counts were monitored by the Live/Dead viability kit, and culturability by plate counts on King's B medium. E. amylovora was able to survive in water from different sources showing a long persistence in irrigation water and maintaining its infectivity for green pears. However, a ...
I am not talking about sugar snap peas (however, that is a possible blog topic) or snapping my fingers…I'm talking about Heirloom Farmers Markets now being a certified SNAP retailer!. What does that mean? Heirloom Farmers Markets is pleased to announce that we can now accept Supplemental Nutrition Assistance Program (SNAP) benefits provided through the U.S. Department of Agriculture (USDA). These benefits can be redeemed at the Trail Dust Town Farmers Market on Friday, Saturday at the Oro Valley Farmers Market and Rillito Park Farmers Market on Sunday. SNAP is a USDA funded program that aims to improve the likelihood that SNAP beneficiaries will choose healthy foods and diet lifestyles despite a limited budget by providing access to fresh local fruits and vegetables. Purchasing food at our local farmers market represents a critical pivot point for change.. This is a unique time for Heirloom Farmers Markets in helping support our region's farmers and producers. Sustainable agriculture provides ...
Denver's premier farmers market featuring fresh produce exclusively from local farmers and growers is back in the heart of downtown! Curated by the nationally renowned Boulder County Farmers Markets, this annual market hosted on Union Station's Plaza is free and open to the public. For the health and safety of Union Station Farmers Market guests, farmers and volunteers, please make a reservation to reserve your shopping window.. Due to COVID-19, Union Station Farmers Market will be following all of Denver's required safety requirements and guidelines. The following items will not be available at Union Station Farmers Market until further notice: food samples, market bucks, live music, seating, cooking demonstrations, artisan shows, and non-profit booths.. Additionally, the Union Station Farmers Market asks that all guests familiarize themselves with the COVID-19 response "Do's" and "Don'ts" below, prior to visiting:. ...
The distribution was done for RIFAN farmers in the three Senatorial zones of the State, with zone one having 900 farmers, zone two, 190 farmers, and zone three, 300 farmers.. Speaking at the presentation of the agricultural inputs, RIFAN State chairman, Alhaji Muhammad Umar Numbu said the inputs are loans which the beneficiaries have to pay either in cash or commodity exchange during harvest season.. According to him, "On behalf of Kaduna State Rice Farmers Association, you are welcome to 2021 wet season special project. As it is today we are operating in the three Senatorial zones of Kaduna State.. "In zone one we have about three clusters, in zone two we have a cluster and zone three we have a cluster. And it goes like this; in zone one we have 900 farmers, 900 hectares, so it is one farmer, one hectare. They are the beneficiaries of this inputs distribution. "We are distributing fertilisers, 30kg of improved rice seedling and inputs and pesticides. This is to ensure the boost in rice ...
The Milwaukee Winter Farmers Market is operated by the Fondy Food Center. The mission of the Fondy Food Center is to connect neighborhoods to fresh, local food - from farm to market to table. We do our work by operating 3 farmers markets, a farm, and coordinating a local farmers market coalition.. The Milwaukee Winter Farmers Market (MWFM) brings together about 50 weekly vendors in the Greenhouse Annex at the Mitchell Park Domes. There, agricultural vendors offer high quality fruit, vegetables, meat, eggs, poultry and dairy products. Local food vendors also bring a wide variety of freshly baked goods, jams, cider, honey, maple syrup, sorghum, sauces and soups, as well as delicious global cuisine.. ...
Highlands Farmers Market is located in the Highlands Square district in Denver, Colorado. This market's urban vibe coupled with its dynamic vendor base has become a Denver favorite. Enjoy quality and diversity among our farm and vendor base, a healthy and delicious selection of ready to consume foods from our trucks and local restaurants and live local music weekly.. Shop for your locally grown fruits and vegetables, meats, eggs, artisan breads, honey, coffee, baked goods, fresh salsas, pastas, natural body care, and massage. We also offer Bloody Marys, Sorbet Mimosas and Craft Beer from our Booze Tent. Highlands Farmers Market seeks to support Colorado farms and businesses by providing the community with a dynamic and inviting market that is beneficial to both its vendors and customers by emphasizing the importance of buying local products. Our farmers sell Colorado-grown organic, transitional and pesticide-free vegetables. Our orchard keepers bring organic and conventional fruit from ...