Hereditary factor X (Stuart-Prower Factor) deficiency is a rare bleeding disorder that causes issues in blood clotting due to a lack of factor X in your blood. Learn more about the symptoms and treatment options and read real patient stories.

Two-site ELISA method for the measurement of coagulation Factor X, in human citrated plasma. Assay designed with affinity purified rabbit polyclonal antibodies for coating the ELISA plate and preparation of Horse Radish Peroxidase (HRP) marker.

Greig, JA, McVey, JH, Waddington, SN, Parker, AL, Buckley, SMK, Havenga, MJE, Nicklin, SA and Baker, AH (2008) Factor X enhances binding and transduction of human cancer cell lines by adenovirus (Ad) serotype 5 vectors but not by Ad35 In: 5th Annual Conference of the British-Society-for-Gene-Therapy, 2008-04-07 - 2008-04-09, Edinburgh, SCOTLAND. Full text not available from this repository ...

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Activated form of factor IX. This activation can take place via the intrinsic pathway of blood coagulation by the action of factor XIa and calcium, or via the extrinsic pathway by the action of factor VIIa, thromboplastin, and calcium. Factor IXa serves to activate factor X to Xa by cleaving the arginyl-leucine peptide bond in factor X ...

1CCF: How an epidermal growth factor (EGF)-like domain binds calcium. High resolution NMR structure of the calcium form of the NH2-terminal EGF-like domain in coagulation factor X.

According to the strategy of a selected experiment type for a set of so-called factors x which represent parameters, initial or boundary values, or drivers of a model M a numerical sample is generated before simulation. This sample corresponds to a multi-run experiment with the model. During the experiment for each single simulation run the factors x are adjusted numerically according to the sample and the factors default values. Each experiment results in a sequence of model outputs for selected state variables z of the model M in the space of all addressed factors {X}. Model outputs can be processed and evaluated after simulation generally on the state space and experiment-type specifically on the factor space ...

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neel9265 neel9265 21.06.2019 Math Secondary School Division Algorithm Formula 2 So, 3x4 + 6x3 - 2x2 - 10x - 5 = (3x2 - 5) (x2 + 2x + 1) + 0 Quotient = x2 + 2x + 1 = (x + 1)2 Zeroes of (x + 1)2 are -1, -1. When we set up a division problem in an equation using our division algorithm, and r = 0, we have the following equation: When this is the case, we say that a is divisible by b. ∴ x = 2 ± √3 ⇒ x - 2 = ±(squaring both sides) ⇒ (x - 2)2 = 3 ⇒ x2 + 4 - 4x - 3 = 0 ⇒ x2 - 4x + 1 = 0 , is a factor of given polynomial ∴ other factors \(=\frac{{{\text{x}}^{4}}-6{{\text{x}}^{3}}-26{{\text{x}}^{2}}+138\text{x}-35}{{{\text{x}}^{2}}-4\text{x}+1}\) ∴ other factors = x2 - 2x - 35 = x2 - 7x + 5x - 35 = x(x - 7) + 5(x - 7) = (x - 7) (x + 5) ∴ other zeroes are (x - 7) = 0 ⇒ x = 7 x + 5 = 0 ⇒ x = - 5, Example 10: If the polynomial x4 - 6x3 + 16x2 -25x + 10 is divided by another polynomial x2 -2x + k, the remainder comes out to be x + a, find k & a. Sol. just create an account. Ah-ha! ...

New England Biolabs supplies a 10X reaction buffer with all of its enzymes. At a 1X concentration this reaction buffer assures optimal activity of the enzyme

New England Biolabs supplies a 10X reaction buffer with all of its enzymes. At a 1X concentration this reaction buffer assures optimal activity of the enzyme

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Order your own lab tests without a doctor visit in Stuart. Call (540) 779-1466 or order online. Fast, private and accurate results in 1-2 days in Stuart, VA. Same day testing available, no insurance needed.

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S-2765, which is specific to activated factor X (FXa), is a short peptide covalently bound to pNA (4-nitroaniline). When attacked by FXa, it releases a free pNA which could be detected by a spectrophotometer at 405 nm. Packaging 10mg Price US$68

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PROGRAM DIRECTOR SHBAM™ HEAD TRAINER BODYCOMBAT™, BODYATTACK™ Gestor e Coordenador Técnico Factor X Hobbies: Passear com a família e bricolage

include ,stdio.h, #include ,stdlib.h, #include ,stdint.h, #include ,libusb.h, #include ,string.h, #include ,assert.h, #include ,gd.h, const uint16_t vid = 0x5345; const uint16_t pid = 0x1234; #define BULK_EP_IN 0x81 #define BULK_EP_OUT 0x03 #define REQ_MODEL \xaa\x55\x05\x00\x00\x00\x02\x09\x36\x00\x00\x00\x00\x00 \ \x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00 \ \x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00 \ \x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00 \ \x00\x00\x00\x00\x00\x00\x00\x00 #define REQ_TIMERLOCK \xaa\x55\x01\x00\xff\x00\xff\xef\x36\x00\xff\x00\x00 \ \x00\x74\x69\x6d\x65\x72\x20\x6c\x6f\x63\x6b\x00\x00 \ \x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00 \ \x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00 \ \x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00 #define REQ_PIX \xaa\x55\x0a\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00 \ \x2e\x70\x69\x78\x00\x00\x00\x00\x00\x00\x00\x00\x00\x00 \ ...

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Sold my Honda and got this the next day(2008 Jeep Wrangler Unlimited X), and the day after that, threw some 26s on it, with 5% tint.....Let me know what...

* found in: XYLENOL ORANGE 0.1% (AQ), Xylenol Orange Triturate R, SUPELCO p-Xylene solution, 5000 µg/mL in methanol, analytical standard, SUPELCO o-Xylene..

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x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x. ...

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Ok, maybe I should add this function to the Save toolbar drop-down and assign a shortcut (Ctrt+Shift+S). The File menu is already overloaded.. , - possibility to search and replace all open files. Again, you could do this (and more) with a script using Tools,Run Script... Use the Save all Documents script as starting point.. , - line numbers to the left of each line. Already implemented in version 3.4. , - toolbar buttons for close and close all. The Close button is the small X on the right or double-click on the document icon on the left. Im not goint to add another button for that. The Close All feature is found in the Window menu where it belongs to. The shortcut is Ctrl+Shift+F4. Im not going to add a toolbar button for that.. , - some shortcut keys are not displayed on the menus (e.g. Ctrl+ ...

well i had unprotected s_x on the last night of my period(mar.14) now like two weeks later ive been have brown stuff in my panties when i wipe its not on the tussie..what is it..

Did I solve these right? 1. f(x)= -3x + 1 g(x)= -4x^2 + x + 2 Find g(f(x) ) -4(-3x+1)^2+(-3x+1)+2 -4(-3x+1)^2-3x+1+2 3-3x-4(-3x+1)^2 3-3x-4+24x-36x^2 =21x-36^2-1 2.f(x)= -2x + 1 g(x)= -3x^2 -x -1 Find (g /f)(x) -3x^2-x-1/-2x+1 3. f(x)=-x +2 g(x)= -4x2 + x ...

UPDATE #7:. (You can close this notice by clicking the X at the top right.). WERE ONLINE AGAIN, AND SHOULD STAY THAT WAY.. Everything we wanted to do has been more than successful. We now have a far faster, stronger and more resilient platform.. Thank you so much for bearing with us. What weve done is summarized for members to read in post #208 of the Record of Server Outages thread.. ...

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Start with: 5x3 - 45x.. You can factor out every term starting with constants; in this case 5.. 5 ( x3 - 9x). Next step, factor out the x so. 5x (x2 - 9). Using FOIL, you can then factor out the term in the parenthesis (x2 - 9). Note there is no x term and the 9 is a perfect square. You get (x -3) (x + 3).. So, in its final form you get. (5x )(x - 3) (x + 3). which can also be written as. 5(x)(x-3)(x+3). ...

Inspired by a recent tweet-exchange with the wonderful Sherlockian David Stuart Davies, I present the ultimate question for Baz fans everywhere....

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A radioimmunoassay (RIA) has been developed for the detection of Russells viper venom in body fluids. This is a competitive binding technique using a monoclonal antibody directed against the factor X activator of Russells viper venom. The sensitivity of the test in urine was 4 ng/ml, in 0.1% bovine serum albumin-phosphate buffered saline it was 20 ng/ml and in serum it was 5 micrograms/ml. This was adequate to detect venom in the serum of four patients bitten by Russells viper. Urine from an isolated kidney preparation perfused with Russells viper venom contained coagulant activity and was positive using the competitive RIA. Testing of sera from other envenomated patients and pure venom from seven other species of snake indigenous to Thailand revealed RIA cross reactivity between cobra venom and Russells viper venom. In practice, the absence of coagulant activity in cobra venom clearly distinguishes between the two. Although further development is required to elucidate the serum factors interfering

Congenital factor X deficiency is a very rare blood-clotting disorder present at birth that results in excessive or prolonged bleeding after an injury or surgery. Factor X is one of 13 proteins involved in proper formation of blood clots. Blood clots are needed to heal wounds, form scabs, and stop bleeding. When factor X levels are low or absent, the blood does not clot correctly, leading to excessive bleeding. Congenital factor X deficiency runs in families and is an autosomal recessive disorder, which means an individual must have two copies of the changed gene that causes the condition. A person with one changed gene would be a carrier of the condition but not have any symptoms. If both parents are carriers, their children have a one in four chance of having the disease. The main symptom of congenital factor X deficiency is excessive and abnormal bleeding. This may occur after childbirth, surgery, trauma, and with menstruation (periods). Bleeding can also occur in the muscles, joints, the ...

Do You Have Factor X Deficiency? Join friendly people sharing true stories in the I Have Factor X Deficiency group. Find support forums, advice and chat with groups who share this life experience. A Factor X Deficiency anonymous support group with in...

Factor X deficiency has no known racial or ethnic predilection. Males and females are equally affected. Patients with congenital factor X deficiency can present at any age. Generally, patients with mo... more

Clotting factor X, or Stuart-Prower factor, is a vitamin K-dependent serine protease that serves as the first enzyme in the common pathway of thrombus formation. Factor X deficiency is a bleeding disorder that can be inherited or acquired.

Activation of prothrombin to thrombin is the key reaction in blood coagulation cascade. We have recently shown that Australian rough scaled snake, Tropidechis carinatus, possesses two parallel prothrombin activator systems. Trocarin D, a venom prothrombin activator produced in the venom gland, plays an offensive role as a toxin, whereas factor X is produced in the liver and plays a role in the hemostatic mechanism. These two proteins are structurally similar and have identical domain architecture. Because of the differences in their physiological roles, and tissue-specific expression, we determined the gene structure of these closely related proteins. Both the genes have eight exons similar to all mammalian factor X genes. All the exon-intron boundaries of these two genes are at the same position and the splice junctions are almost identical. Partial sequencing of the introns shows that they share a very high degree of sequence identity indicating that the gene duplication is a recent event. ...

Factor Xa is the activated form of the coagulation factor thrombokinase, known eponymously as Stuart-Prower factor. Factor X is an enzyme, a serine endopeptidase, which plays a key role at several stages of the coagulation system. Factor X is synthesized in the liver. The most commonly used anticoagulants in clinical practice, warfarin and the heparin series of anticoagulants and fondaparinux, act to inhibit the action of Factor Xa in various degrees. Traditional models of coagulation developed in the 1960s envisaged two separate cascades, the extrinsic (tissue factor (TF)) pathway and the intrinsic pathway. These pathways converge to a common point, the formation of the Factor Xa/Va complex which together with calcium and bound on a phospholipids surface generate thrombin (Factor IIa) from prothrombin (Factor II). A new model, the cell-based model of anticoagulation appears to explain more fully the steps in coagulation. This model has three stages: 1) initiation of coagulation on TF-bearing ...

Supplementary MaterialsS1 Methods: Detailed explanation of prekallikrein production and prothrombin/factor X lacking plasma assays. Aliquots of 10 L PD184352 ic50 had been taken and generated kallikrein enzymatic activity was determined using the specific chromogenic substrate S2302 (2 mM). The kinetics of p-nitroaniline formation were monitored at 405 nm and curves are representative data from at least three independent experiments. Inset shows the dose-response curve. The amounts of plasma derived kallikrein generated by LOBE was estimated using a calibration curve made with known concentrations of purified kallikrein and thus expressed as pmol of equivalent kallikrein/mL/min.(TIF) pntd.0007197.s004.tif (459K) GUID:?7403B6A2-C7C2-4032-B696-330A483F7AED S4 Fig: LOBE-induced kallikrein generation in factor X and prothrombin deficient PD184352 ic50 plasma. To further confirm LOBE-induced kallikrein activation specificity, the main procoagulant factors, FX and prothrombin (PThr), were depleted ...

Membrane anchoring of tissue factor (TF), the cell receptor for coagulation factor VIIa (VIIa), exemplifies an effective mechanism to localize proteolysis at the cell surface. A recombinant TF mutant (TF1-219), deleted of membrane spanning and intracellular domains, was used to evaluate the role of phospholipid interactions for assembly of substrate with the catalytic TF.VIIa complex. TF1-219 was secreted by cells rather than expressed as a cell membrane protein. Unlike free VIIa, TF1-219 as well as the TF1-219.VIIa complex demonstrated no stable association with phospholipid. In the absence of lipid, kinetic evaluation of substrate factor X cleavage by free VIIa, TF.VIIa, and TF1-219.VIIa suggests that the catalytic function of VIIa rather than substrate recognition is enhanced by complex formation. Furthermore, compared with free factor X, factor X on phospholipid was preferentially cleaved as a substrate by TF1-219.VIIa. TF-dependent initiation of the coagulation protease cascades thus ...

Used in the treatment of bleeding episodes in hemophilia A or B. NovoSeven is recombinant Factor VIIa and, when complexed with tissue factor can activate coagulation Factor X to Factor Xa, as well as coagulation Factor IX to Factor IXa. Factor Xa, in complex with other factors, then converts prothrombin to thrombin, which leads to the formation of a hemostatic plug by converting fibrinogen to fibrin and thereby inducing local clotting ...

TY - JOUR. T1 - Assembly of the intrinsic factor X activating complex. T2 - Interactions between factor IXa, factor Vllla and phospholipid. AU - van Dieijen, Gerbrand. AU - van Rijn, Jan L.M.L.. AU - Govers-Riemslag, Jose W.P.. AU - Hemker, H. Coenraad. AU - Rosing, Jan. PY - 1985. Y1 - 1985. U2 - 10.1055/s-0038-1661322. DO - 10.1055/s-0038-1661322. M3 - Article. VL - 53. SP - 396. EP - 400. JO - Thrombosis and Haemostasis. JF - Thrombosis and Haemostasis. SN - 0340-6245. IS - 3. ER - ...

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Factor X is a glycoprotein, which plays a central role in blood coagulation. Factor X isactivated by a sequence of reaction beginning with contact activation and involving factors XII, XI, IX and VIII. This is termed as the intrinsic pathway*. A functionally identical prothrombinase can be produced in a matter of seconds by tissue thromboplastins. This involves a sequence of reactions termed as extrinsic pathway* which, in addition to factors X and V requires only factor VIL Thus, only the two processes mentioned above i.e. contact activation and tissue thromboplastin initiate blood coagulation. It proceeds initially via two separate pathways i.e. the tissue activated extrinsic pathway and the contact activated intrinsic pathway. Later steps leading to the formation of fibrin proceed via a common pathway, requiring factors IX, V, PF-3, prothrombin and fibrinogen ...

1WSS: Structure of human factor VIIa/tissue factor in complex with a peptide-mimetic inhibitor: high selectivity against thrombin by introducing two charged groups in P2 and P4.

Coagulation factor X (FX) plays an important role in the immune response of mammals. In this study, the full length cDNA sequence of the ayu FX gene, 1817 bp in length excluding 3-polyA tail, was determined for the first time. The sequence contained an open reading frame, which encoded a protein of 453 amino acids with a molecular weight of 5.07 × 104. The predicted protein had motifs typical of animal FX, and its N-terminal 24 residues were the signal peptides. Sequence comparison showed that ayu FX shared 53% amino acid sequence identity with zebrafish FX. In healthy ayu, FX mRNA was expressed mainly in the liver and weakly in the brain and gill. After Listonella anguillarum ...

While you are welcome to contact an attorney at Stuart & Branigin LLP, you should be aware that this website presents general information about Stuart & Branigin LLP and is not intended as legal advice, nor should you consider it as such. You should not act upon this information without seeking professional counsel.. Please keep in mind that merely contacting Stuart & Branigin LLP will not establish an attorney-client relationship. Stuart & Branigin LLP cannot represent you until the firm knows there would not be a conflict of interest and the firm determines that it is otherwise able to accept the engagement. Accordingly, please do not send Stuart & Branigin LLP any information or documents until a formal attorney-client relationship has been established through an interview with an attorney and you receive authorization in the form of an engagement letter from Stuart & Branigin LLP. Any information or documents sent prior to your receipt of an engagement letter cannot be treated as ...

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Coagulation factors such as factor V, factor VIII and factor X play a role in blood clotting. Lab tests can measure clotting factors to help diagnose the cause of excessive bleeding (bleeding disorder).

And I noted that the components of the system beyond the fork in the pathway are fibrinogen, prothrombin, Stuart factor, and proaccelerin. So I was focusing on a particular part of the pathway, as I tried to make clear in Darwins Black Box. If we could go to the next slide. Those components that I was focusing on are down here at the lower parts of the pathway. And I also circled here, for illustration, the extrinsic pathway. It turns out that the pathway can be activated by either one of two directions. And so I concentrated on the parts that were close to the common point after the fork. So if you could, I think, advance one slide. If you concentrate on those components, a number of those components are ones which have been experimentally knocked out such as fibrinogen, prothrombin, and tissue factor. And if we go to the next slide, I have red arrows pointing to those components. And you see that they all fall in the area of the blood clotting cascade that I was specifically restricting my ...

And I noted that the components of the system beyond the fork in the pathway are fibrinogen, prothrombin, Stuart factor, and proaccelerin. So I was focusing on a particular part of the pathway, as I tried to make clear in Darwins Black Box. If we could go to the next slide. Those components that I was focusing on are down here at the lower parts of the pathway. And I also circled here, for illustration, the extrinsic pathway. It turns out that the pathway can be activated by either one of two directions. And so I concentrated on the parts that were close to the common point after the fork. So if you could, I think, advance one slide. If you concentrate on those components, a number of those components are ones which have been experimentally knocked out such as fibrinogen, prothrombin, and tissue factor. And if we go to the next slide, I have red arrows pointing to those components. And you see that they all fall in the area of the blood clotting cascade that I was specifically restricting my ...

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Constituent composed of protein and phospholipid that is widely distributed in many tissues. It serves as a cofactor with factor VIIa to activate factor X in the extrinsic pathway of blood coagulation.

L-Glutamine is an essential amino acid commonly used in cell culture. However, it is notably unstable in liquid media, spontaneously breaking down to release cytotoxic amines. This stabilized compound (L-alanyl-L-glutamine) prevents degradation and cytotoxicity, markedly increasing shelf life. This solution is prepared at a convenient 200mM (100x) concentration. Sterile- ...

Downloadable! We present a simple way to estimate the effects of changes in a vector of observable variables X on a limited dependent variable Y when Y is a general nonseparable function of X and unobservables. We treat models in which Y is censored from above or below or potentially from both. The basic idea is to first estimate the derivative of the conditional mean of Y given X at x with respect to x on the uncensored sample without correcting for the effect of changes in x induced on the censored population. We then correct the derivative for the effects of the selection bias. We propose nonparametric and semiparametric estimators for the derivative. As extensions, we discuss the cases of discrete regressors, measurement error in dependent variables, and endogenous regressors in a cross section and panel data context.

Stuart T. Maschwitz, Visual Effects: Star Wars. Stuart T. Maschwitz is known for his work on Star Wars: Episode IV - A New Hope (1977), Star Wars: Episode V - The Empire Strikes Back (1980) and Star Wars: Episode VI - Return of the Jedi (1983). He has been married to Michelle Stock since October 8, 2005.

P.M. STUART - REFLECT HONESTLY ON QUESTIONS on The Bajan Reporter | Prime Minister Freundel Stuart has called on Barbadians to continue reflecting on those…

Factor Xiii, Plasma, Bleeding, Mutation, Fibrin, Lead, Cells, Time, Life, Patients, Concentrations, Factor X, Treatment, Vitamin K, Antigen, DNA, DNA Sequencing, Laboratory, Plasminogen, Sister

RFX5 antibody (regulatory factor X, 5 (influences HLA class II expression)) for IHC-P, IP, WB. Anti-RFX5 pAb (GTX29255) is tested in Human samples. 100% Ab-Assurance.

Max - Max (Myc-DDK-tagged ORF) - Rat MYC associated factor X (Max), (10 ug) available for purchase from OriGene - Your Gene Company.

Szukasz rozwiązania jak wzmocnić swoją odporność? Sprawdź ofertę na stronie TFX Pharma i kup Thymus Factor X - preparat z ekstraktem z grasicy!

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ROCHESTER, New York -- April 6, 2011 -- The invaluable resource, Lynda.com, which is considered by many to be one of the most comprehensive software training & tutorial video library online recently expanded their topics of knowledge. This time turning to teaching those about Screencasting, and enlisting the venerable Chris Breen to create a tutorial on recording with Snapz Pro X.. ...

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A central feature of this adaptable, robust microscope range is the stable mechanism which can be adjusted precisely. This is emphasized by the functional and ergonomic design ...

German carmaker Audi says its planning to unveil an electric sport SUV concept with a range of over 310 miles (500 kilometers)-well beyond the range of rival carmaker Teslas Model S and soon-to-launch Model X.

Buy Chemistry and Life An Introduction to General, Organic, and Biological Chemistry by Stuart J. Baum at TextbookX.com. ISBN/UPC: 9780130821812. Save an average of 50% on the marketplace.

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Stuart I. Mannering is the author of this article in the Journal of Visualized Experiments: Extraction of Tissue Antigens for Functional Assays

Welcome to our Ball Arch and Top of Foot page. Contact Dr. Stuart L. Jablon today at 860-295-8791 or visit our office servicing Marlbourough, CT

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Stuart Baxter is focusing on the positives after losing to Mamelodi Sundowns. Baxter feels that Kaizer Chiefs dominated the game and the scoreline wasnt fair.

Dangerous Garden by David Stuart describes the quest for plants to access gods, change lives, end disease and pain, enhance sex, expand minds, and kill.

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Check out Stuarts entry to the LensCulture Exposure Awards 2015! Share this post and help discover the best photography from all over the world! #lensculture