The advantage of left transthoracic esophagectomy is readily apparent in that it affords a surgical resection with a single incision. In addition to the obvious advantage of decreasing the patients discomfort, the left transthoracic esophagectomy also can be performed in much less time than the Ivor Lewis or McKeown esophagectomy, with operative time averaging 2 to 3 hours.6 The left transthoracic approach does have a number of disadvantages that should be noted. First, although the division of the diaphragm provides excellent visualization of the left upper quadrant of the abdomen via the left chest, the remainder of the abdomen cannot be accessed using this approach. As a result of the limited abdominal exposure, adequate dissection of the pylorus cannot be achieved to perform pyloromyotomy. Many surgeons profess that gastric drainage is an essential component of esophageal reconstruction with gastric conduit placement after esophagectomy and identify the inability to perform a drainage ...

TY - JOUR. T1 - Can Minimally Invasive Esophagectomy Replace Open Esophagectomy for Esophageal Cancer? Latest Analysis of 24,233 Esophagectomies From the Japanese National Clinical Database. AU - Yoshida, Naoya. AU - Yamamoto, Hiroyuki. AU - Baba, Hideo. AU - Miyata, Hiroaki. AU - Watanabe, Masayuki. AU - Toh, Yasushi. AU - Matsubara, Hisahiro. AU - Kakeji, Yoshihiro. AU - Seto, Yasuyuki. PY - 2020/7/1. Y1 - 2020/7/1. N2 - OBJECTIVE: We aimed to elucidate whether minimally invasive esophagectomy (MIE) can be safely performed by reviewing the Japanese National Clinical Database. SUMMARY OF BACKGROUND DATA: MIE is being increasingly adopted, even for advanced esophageal cancer that requires various preoperative treatments. However, the superiority of MIEs short-term outcomes compared with those of open esophagectomy (OE) has not been definitively established in general clinical practice. METHODS: This study included 24,233 esophagectomies for esophageal cancer conducted between 2012 and 2016. ...

BACKGROUND: Minimally invasive esophagectomy is rapidly emerging as a suitable surgical alternative to the open technique. This retrospective comparative study aimed to compare two minimally invasive techniques for esophagectomy: transhiatal laparoscopy with intrathoracic or cervical anastomosis (group A) and right thoracoscopy in prone position followed by laparoscopy and left cervicotomy (group B) performed by the same surgeon (G.B.C.). The operative time, perioperative blood loss, intensive care and total hospital stays, peri- and postoperative morbidity, in-hospital mortality, number of lymph nodes dissected, and survival were the outcome measures.. METHODS: Between April 1999 and August 2005, 24 patients (group A) and 15 patients (group B) underwent minimally invasive esophagectomy for cancer in the authors department. Their median age was 61 years in group A and 61 years in group B. Preoperatively, the endoscopic location of the tumor was in the upper third in 2 cases (1 vs 1), the middle ...

TY - JOUR. T1 - An early experience using the technique of transoral OrVil EEA stapler for minimally invasive transthoracic esophagectomy. AU - Jaroszewski, Dawn E.. AU - Williams, Dustin G.. AU - Fleischer, David E.. AU - Ross, Helen J.. AU - Romero, Yvonne. AU - Harold, Kristi L.. PY - 2011/11. Y1 - 2011/11. N2 - Background: Minimally invasive esophagectomy (MIE) has been performed using a variety of techniques evolving during the past decade. We present our initial experience and outcomes of patients undergoing transthoracic MIE using a circular end-to-side anastomosis created with the transorally directed EEA circular stapler OrVil (Covidien, New Haven, CT). Complications, including anastomotic leak and stricture occurrence, are reviewed. Methods: A retrospective review evaluated consecutive patients undergoing MIE for esophageal cancer or related disease with intrathoracic end-to-side anastomoses using the transorally directed EEA circular stapler from December 2007 to May 2010. Medical ...

Assess short and long term outcomes after minimally invasive esophagectomy(MIE) compared to open esophagectomy. Measure standard observer derived outcomes such as morbidity, mortality, tumor recurrence and also patient derived outcomes, in particular quality of life (QOL) using the MOS SF36 questionnaire. Evaluate whether the SF36 will accurately reflect pre and postoperative changes in clinical status in this patient group.Compare the results of this global QOL instrument (SF 36) to disease specific scales of dysphagia and reflux. Assess the impact of adjuvant or neoadjuvant therapy on QOL in this patient group and determine if any advantages of MIE can be demonstrated ...

Transhiatal blunt esophagectomy has been reported as a safe and effective procedure for the palliation of carcinoma of the esophagus. Avoidance of a thoracotomy eliminates the morbidity associated with this procedure, and creation of a cervical esophagogastric anastomosis avoids the catastrophic sequelae of an intrathoracic anastomotic leak. Moreover, use of the procedure for palliation does not preclude excellent 1-year survival rates. We report early results in five consecutive patients with esophageal carcinoma who underwent transhiatal blunt esophagectomy. Five patients had 22 complications, including one with a fascial dehiscence, pyloroplasty leak, and localized mediastinal abscess requiring a second laparotomy. One patient died in the hospital postoperatively of massive aspiration pneumonitis. Our results compare favorably with those reported in the literature. We believe that transhiatal blunt esophagectomy avoids the morbidity and mortality of a thoracotomy and an intrathoracic ...

Author(s): Luketich, James D; Pennathur, Arjun; Franchetti, Yoko; Catalano, Paul J; Swanson, Scott; Sugarbaker, David J; De Hoyos, Alberto; Maddaus, Michael A; Nguyen, Ninh T; Benson, Al B; Fernando, Hiran C | Abstract: The primary aim of this trial was to assess the feasibility of minimally invasive esophagectomy (MIE) in a multi-institutional setting.Esophagectomy is an important, potentially curative treatment for localized esophageal cancer, but is a complex operation. MIE may decrease the morbidity and mortality of resection, and single-institution studies have demonstrated successful outcomes with MIE.We conducted a multicenter, phase II, prospective, cooperative group study (coordinated by the Eastern Cooperative Oncology Group) to evaluate the feasibility of MIE. Patients with biopsy-proven high-grade dysplasia or esophageal cancer were enrolled at 17 credentialed sites. Protocol surgery consisted of either 3-stage MIE or Ivor Lewis MIE. The primary end point was 30-day mortality. Secondary end

Dennis Leung, MS, John Howington, MD, Mark Talamonti, MD, Jason Long, MD, Michael Ujiki, MD. NorthShore University HealthSystem, Chicago, IL.. Introduction: Several complications after esophagectomy with gastric pull-up are associated with ischemia within the gastric conduit. We aimed to assess the feasibility of laparoscopic ischemic preconditioning of the stomach prior to thoracotomy, esophagectomy, and gastric pull-up with an intrathoracic anastomosis.. Methods: We conducted a retrospective review of 12 consecutive patients between October 2008 and December 2009 with esophageal adenocarcinoma (Stage I - III) undergoing laparoscopic gastric ischemic conditioning prior to esophagectomy. Conditioning included laparoscopic ligation of the left and short gastrics, celiac node dissection, and jejunostomy tube placement. Formal resection and reconstruction was then performed 4-10 days later.. Results: Of our 12 patients, 84.6% received neoadjuvant chemo/XRT. Reoperation occurred in 2 cases prior to ...

The short-term outcome of three-field minimally invasive esophagectomy for Siewert type I esophagogastric junctional adenocarcinoma. - Liu Hong, Yujie Zhang, Hongwei Zhang, Jianjun Yang, Qingchuan Zhao

Esophagectomy for benign or malignant disease of the esophagus can be performed using a transhiatal technique or Ivor Lewis technique (combined laparoto

A total of 251 patients underwent transthoracic esophagectomy with extended en-bloc cervicothoracoabdominal (three-field) lymphadenectomy between January 1998 and December 2002 at Juntendo University in Japan. A total of 27,774 lymph nodes were dissected, and the average number of dissected lymph nodes per patient was 111. The lymph nodes removed en bloc with the specimen were dissected and classified into respective lymph node groups immediately after the operation by the surgeons who performed the esophagectomy, as outlined in the Japanese Guidelines for Clinical and Pathologic Studies on Classification of Esophageal Cancer6 (Fig. 18-1). This provides a more detailed lymph node classification than the AJCC Cancer Staging Manual.7 The pattern of lymphatic spread was investigated in detail, and the final pathologic diagnosis of lymph node metastasis was compared with the preoperative clinical evaluation to assess the accuracy of ...

Keyword(s): anastomotic leak, C-reactive protein, conservative management, critically ill, CRP, CT scan, curative treatment, diagnostic, empyema, endoscopic management, esophageal cancer, evidence-based protocol, ICU readmission, intensive care unit, leakage, mediastinal abscess, mediastinal fluid collection, MIE, minimally invasive esophagectomy, minimally invasive technique, morbidity, mortality, nasogastric tube, neoadjuvant chemotherapy, NG tube, pulmonary infection, suction drainage, treatment, VATS, video-assisted thoracoscopic surgery. MIE-47 sec Lancet 2012. Ann Surg Oncol 2012. Eur J Cardiothorac Surg 2005. Langenbecks Arch Surg 2015. Am Surg 2014. ...

Zhigang Li from Shanghai, China, will share with you the latest insights in How to streamline minimally invasive esophagectomy?. After this lecture, an interactive Q and A debate will be held ...

The first randomized controlled trial on early versus late oral feeding after minimally invasive esophagectomy and the ongoing quest for more evidence

Section I Head and Neck -- ch. 1 Radical Neck Dissection / Jesus E. Medina -- ch. 2 Modified Neck Dissection / Ashok R. Shaha -- ch. 3 Superficial Parotidectomy / Ashok R. Shaha -- ch. 4 Excision of Submandibular Gland and Submandibular Triangle Dissection / Jesus E. Medina -- Section II Thoracic -- ch. 5 Radical Pneumonectomy / Lorenzo Spaggiari -- ch. 6 Resection Of Pulmonary Metastases / Jack A. Roth -- ch. 7 Video-Assisted Thoracoscopic Lobectomy / Ali Mahtabifard -- ch. 8 Thoracoscopic Lung Biopsy / Ali Mahtabifard -- ch. 9 Lung Volume Reduction Surgery / Michael K.Y. Hsin -- ch. 10 Chest Wall Resection/Reconstruction / Antonio Briccoli -- Section III Esophagus -- ch. 11 Radical Esophagectomy With Two- Or Three-Field Lymphadenectomy / Herbert Decaluwe -- ch. 12 Transhiatal Esophagectomy Via Laparoscopy And Transmediastinal Endodissection / Riccardo Rosati -- ch. 13 Laparothoracoscopic Esophagectomy / James D. Luketich -- ch. 14 Esophagectomy By Thoracoscopy In Prone Position Followed by ...

Surgery is the standard treatment for esophageal (food pipe) cancer. Esophageal cancer is known to spread to the lymph nodes (glands) adjacent to the esophagus. The extent of lymph nodes that need to be removed along with removal of the esophagus is a controversial topic. The basic surgery will remain the same i.e., the foodpipe in the chest will be removed and a new substitute will be created from the stomach and joined to the foodpipe in the neck. This will involve incisions in the chest, abdomen and neck. We intend to compare two types of lymphadenectomy (removal of lymph nodes) - the two field lymphadenectomy, whereby the lymph nodes in the abdomen and the lower half of the chest will be removed and three field lymphadenectomy, wherein lymph nodes in the abdomen, the whole chest and the lower neck will be removed. Both these procedures are practised widely worldwide and there is no definite scientific evidence showing the superiority of either of them. We are conducting this study to see ...

Esophagectomy is a surgical procedure to remove part of the tube between your mouth and stomach (esophagus) and then reconstruct it using part of another organ, usually the stomach. Esophagectomy is a common treatment for advanced esophageal cancer, and is used occasionally for Barretts esophagus if precancerous cells are present.

TY - JOUR. T1 - Perioperative management for esophagectomy. AU - Suzuki, Takeshi. AU - Morisaki, Hiroshi. PY - 2014/5. Y1 - 2014/5. N2 - Esophagetomy is considered as one of the most invasive surgical procedures. Despite marked advances in surgical techniques, anesthetic management and intensive care, the morbidity and mortality remain still high compared with the other types of surgery. Excessive inflammatory response after surgery induces over-production of inflammatory cytokines, leading to the development of vital organ failures. Anesthesiologists should pay much attention to perioperative management of patients undergoing esophagectomy since they are potentially at high risks of respiratory and cardiovascular complications caused by excessive stress with cervical thoracic and abdominal procedures. During surgery, many interventions such as effective epidural anesthesia, restrictive fluid management lung protective strategy, maintenance of hemodynamic stability and steroid therapy should be ...

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Esophagectomy is a major operation whereby intraoperative technique and postoperative care must be optimal. Even in expert hands, the complication rate is as high as 59%. Here the authors discuss the role of surgical adjuncts, including enteral access, nasogastric decompression, pyloric drainage procedures, and anastomotic buttressing as adjuncts to esophagectomy and whether they reduce perioperative…

en] OBJECTIVE: The aims of our study were to determine if using the colon as a digestive transplant after oesophagectomy for cancer was associated with increased postoperative complications, and to assess the impact of preoperative radiochemotherapy on postoperative hospital outcome. METHODS: From January 1990 to December 1998, 130 patients underwent oesophageal resection for malignancy. There were 103 males and 27 females (age: 61.3+/-11.5 years). Indications were squamous cell carcinoma in 69 patients and adenocarcinoma in 61. Preoperatively 30 patients (eight in stage IIB, 18 in stage III, and four in stage IV) received radiochemotherapy. There were 84 subtotal oesophagectomies, with anastomosis in the neck in 44 patients and at the thoracic inlet in 40, and 46 distal oesophageal resections. Digestive continuity was restored with the stomach in 92 patients (age: 63.4+/-10.2 years) and the colon in 38 (age: 52.3+/-12.8 years). With the exception of age (P,0.0001), there was no significant ...

Signs and symptoms of this cancer include heartburn, trouble swallowing, chest pain and weight loss. Our approach to esophageal cancer includes minimally invasive esophagectomy, or a less-invasive approach than other procedures. As one of the only hospitals in the area using this technique, patients often enjoy a higher quality of life and reduced complications after this surgery.

OBJECTIVES: We aimed to examine the association between total number of resected nodes and survival in patients after esophagectomy with and without nCRT. BACKGROUND: Most studies concerning the potentially positive effect of extended lymphadenectomy on survival have been performed in patients who underwent surgery alone. As nCRT is known to frequently sterilize regional nodes, it is unclear whether extended lymphadenectomy after nCRT is still useful. METHODS: Patients from the randomized CROSS-trial who completed the entire protocol (ie, surgery alone or chemoradiotherapy + surgery) were included. With Cox regression models, we compared the impact of number of resected nodes as well as resected positive nodes on survival in both groups. RESULTS: One hundred sixty-one patients underwent surgery alone, and 159 patients received multimodality treatment. The median (interquartile range) number of resected nodes was 18 (12-27) and 14 (9-21), with 2 (1-6) and 0 (0-1) resected positive nodes, ...

نحن نصف رواية داخل الصدر المريء تقنية anastomotic مصممة لخلق anastomosis قطركبير مع الحفاظ في وقت واحد على إمدادات الدم قناة للحد من...

Vi beskriver en ny intrathorax esophagogastrisk anastomotisk teknikk designet for å skape en stor diameter anastomose samtidig...

Dr Morse is clinically very active and sees new patients weekly. His clinical interests revolve around malignancies of the chest, especially lung and esophageal cancer, as well as the treatment a variety of benign esophageal conditions, including achalasia, paraesophageal hernia and gastroesophageal reflux disease. Dr. Morse has taken a lead role in the development of a minimally invasive esophagectomy program at MGH. This work has led to a number of manuscripts including a direct comparison of open vs. minimally invasive esophagectomy ...

All information about the latest scientific publications of the Clínica Universidad de Navarra. Preoperative chemotherapy followed by esophagectomy compared with surgery alone in the treatment of squamous cell carcinoma of the esophagus

Surgery for esophageal cancer: indications, evaluation, characterization types of surgery (esophagectomy, reconstructive plastic, approaches to surgery). Palliative surgery.

Longitudinal study of esophageal mucosal damage after esophagectomy and gastric interposition: relationship between reflux-related mucosal injury and Notch signaling

Esophagectomy is performed by surgeons at Massachusetts General Hospital as both a minimally invasive and standard open procedure to remove a diseased esophagus and reconstruct the gastrointestinal tract.

Gains in surgical proficiency in esophagectomy for cancer are associated with measurable improvements in short-term and long-term mortality results.

Prosciak, M. P., Stawicki, S. P., Davido, H. T., Thomas, Y. M., Lindsey, D. E., Whitmill, M. L., Steinberg, S. M., Gerlach, A. T., & Cook, C. H. (2009). Atrial Fibrillation after Esophagectomy: A Marker of Increased Morbidity and Mortality. American Journal of Respiratory Critical Care Medicine, 179 ...

A pathological complete response (pCR) after neoadjuvant chemoradiotherapy (NACRT) ensures long-term survival in esophageal squamous cell carcinoma (ESCC) patients following esophagectomy, but pCR patients are a minority. The aim here was to identify prognostic factors in patients with non-pCR ESCC after NACRT. This is a retrospective study. Investigated were 5-year overall survival (OS), disease-specific survival (DSS), and relapse-free survival (RFS) among non-pCR ESCC patients divided into pT0N0, primary site pCR (pT0N+), lymph node pCR (pT+N0), and non-pCR in both the tumor and lymph node (pT+N+) subgroups after NACRT and esophagectomy. Focusing on the SUVmax reduction rate in the primary tumor in 88 patients who underwent FDG-PET before and after NACRT, we used univariate and multivariate Cox proportional hazard models to identify prognostic factors. Although there were no significant survival differences among non-pCR ESCC patients with pT0N+, pT+N0, or pT+N+, survival rate among pT+N+patients was

Comparison of end-to-side hand-sewn and side-to-side stapled cervical esophagogastric anastomosis in patients with lower thoracic esophageal cancer undergoing transhiatal esophagectomy: an Iranian retrospective cohort study. BMC Gastroenterol. 2020 Jul 31; 20(1):250 ...

Esophageal cancers usually exhibit lymph-node metastases. Although a solitary lymph-node metastasis is occasionally found, the involvement of an intrathoracic paraaortic node is rare. We present here an intrathoracic mid-esophageal cancer case in which an accompanying solitary retroaortic mass was found within the posterior mediastinum by integrated positron emission tomography/computed tomography. For diagnosis, thoracoscopic resection of the mass was performed from a left thoracic approach, and histology revealed it to be a squamous cell carcinoma metastasized from the esophageal cancer. Upon radical esophagectomy after neoadjuvant therapy as a T3N1M0 Stage IIIa (AJCC/UICC) cancer, the esophageal cancer was found to have invaded unexpectedly deeply in the vicinity of the descending aorta. Another lymph node within the paraaortic region was also involved (T4N1M0 Stage IIIc). The present case and other cases we review here inform our understanding of metastasis to intrathoracic paraaortic nodes ...

TY - JOUR. T1 - Esophageal epidermoid carcinoma metastasis to the stomach. AU - Liu, H. J.. AU - Huang, M. S.. AU - Huang, B. S.. AU - Wang, L. S.. AU - Hsu, H. K.. AU - Hsu, W. H.. AU - Huang, M. H.. AU - Chien, K. Y.. PY - 1994. Y1 - 1994. N2 - Epidermoid carcinoma of the esophagus with metastasis to the stomach, diagnosed before autopsy, is very rare. The first case in Taiwan is presented. Both the epidermoid carcinoma of the esophagus and stomach were the same pathologic type, were discrete and not continuous, and had not metastated from other origins. The route of metastasis seems to have been via the rich submucosal lymphatics. Although the prognosis was very poor, the 73-year-old male received operation and postoperative radiotherapy, and had lived well in the past one year and to the present. Thus transhiatal subtotal esophagectomy, total gastrectomy and reconstruction with left side colon may be the surgical treatment of choice.. AB - Epidermoid carcinoma of the esophagus with ...

Backgrounds: Esophageal carcinoma (EC) is one of the most common cancers worldwide with high morbidity and mortality. While, the prognosis of EC is generally poor because of the relatively late stage for most patients at the time of diagnosis (1), even if a surgery was perform...

Endoscopic resection was associated with similar cancer-specific survival compared with esophagectomy in patients with stage T1b esophageal adenocarcinoma, according to research presented at the ACG Virtual Annual Scientific Meeting.Daryl Ramai, MD, from The Brooklyn Hospital Center, said esophagectomy has been the standard for the treatment of early esophageal cancer, but it is associated with high mortality and morbidity.Early esophageal cancer can be effectively treated with endoscopic therapy, as there is a low risk of lymph node metastasis, he said. Most studies haveRead More. ...

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Learn about the types of esophagus cancer and surgical treatment options such as a minimally invasive esophagectomy at Brigham and Womens Hospital.

Experimental studies suggest that pretreatment with β-agonists might prevent acute lung injury (ALI).To determine if in adult patients undergoing elective esophagectomy, perioperative treatment with inhaled β-agonists effects the development of early ALI.We conducted a randomized placebo-controlled trial in 12 UK centers (2008-2011). Adult patients undergoing elective esophagectomy were allocated to prerandomized, sequentially numbered treatment packs containing inhaled salmeterol (100 μg twice daily) or a matching placebo. Patients, clinicians, and researchers were masked to treatment allocation. The primary outcome was development of ALI within 72 hours of surgery. Secondary outcomes were ALI within 28 days, organ failure, adverse events, survival, and health-related quality of life. An exploratory substudy measured biomarkers of alveolar-capillary inflammation and injury.A total of 179 patients were randomized to salmeterol and 183 to placebo. Baseline characteristics were similar. Treatment with

Hellenic Society of Gastroenterology. Annals of Gastroenterology.Journal part.Letter.2014 . Creators: Osakwe, Nonso, Lee, Paul C., Paul, Subroto. Types: info:eu-repo/semantics/article, info:eu-repo/semantics/publishedVersion

However, others emphasized that those who received haloperidol in this study took a relatively high mean modal dose (12 mg per day) and 81 of the patients taking haloperidol took a daily dose of 7. 3. The majority of published work has focused on enzyme systems active at the savella and zanaflex surface. Vs the last decade, a variety of radiolabelled probes have been used to characterize brain NPY receptor sites including pHNPY(Martelfl.

I was diagnosed with OGJ cancer on 15 August 2012, and was initially told it had metastasised to the liver - in fact they said it was probably terminal. but they got it wrong and I transferred to another hospital. Within days I was being fast tracked onto ECX chemo. It was too aggressive, so they stopped it midway and six weeks later I had surgery. My tumour was about 5.5cm by the time of the surgery. About a third of my stomach was retained to form a tube to connect to the remainder of my oesophagus, and the last third or so of that was removed. Within 5 days I was eating soft food, and within 6 days I was home. It was a slow process of recovery and I continued to lose weight gradually for six months post surgery - but I was warned that this was likely. I was back at work within four and half months, and began to level off weight-wise. I had calorie dense food all the time, so every savoury dish was glossy with cheese sauce and I enriched milk with spoonsful of powered milk. I ate lots of nuts ...

TY - JOUR. T1 - Two cases of esophageal cancer with portal hypertension treated with esophagectomy with venous shunt procedure. AU - Kikuchi, Kenji. AU - Okushiba, Shunichi. AU - Kitashiro, Shuuji. AU - Kawarada, You. AU - Shichinohe, Toshiaki. AU - Yamamoto, Yuhei. AU - Komatsu, Yoshito. AU - Morikawa, Toshiaki. AU - Kato, Hiroyuki. AU - Kondo, Satoshi. PY - 2006/2. Y1 - 2006/2. N2 - Some 4-6% of esophageal cancer patients have liver cirrhosis, and the incidence of complication after esophageal cancer surgery in portal hypertension due to liver cirrhosis is high. One serious complication is anastomotic leakage due to congestion of venous flow in the early postoperative course. We conducted a venous shunt in addition to reconstruction of the esophagus after esophagectomy using the gastric tube in two cases of esophageal cancer with portal hypertension to avoid congestion in the gastric tube. In Case 1, a patient with portal hypertension due to liver cirrhosis had esophageal cancer type-III. ...

To investigate the application of endoscopic injection of human fibrin sealant in treatment of patients with intrathoracic anastomotic leakage after esophagectomy. A total of 179 patients who underwent intrathoracic anastomosis after esophageal cancer surgery in our department From December 2012 to May 2015 were retrospectively analyzed. The clinical data and treatment of 7 patients with postoperative intrathoracic anastomotic leakage were analyzed and discussed. On Day 28 after operation, the 7 patients were given endoscopic injection of human fibrin sealant to seal the anastomotic leakage, and the changes in drainage volume, body temperature, CRP, white blood cell count and other indicators were compared before and after endoscopic intervention. After endoscopic injection of human fibrin sealant in all 7 patients with intrathoracic anastomotic leakage, the volume of para-anastomotic drainage, CRP, and WBC count were improved compared with those before treatment. Relevant data were analyzed, and the

This study reports a case of Unilateral Endogenous Fungal Endophthalmitis After Esophageal Cancer Surgery. One patient presented with a month-long loss of vision in his left eye, he had surgery for esophageal cancer 2 months earlier. The patient underwent cataract surgery (by phacoemulsification) in the left eye combined with 25-gauge vitrectomy and silicone oil tamponade. The microbiological culture pointed to infection with Candida albicans. At 3-month follow-up, the unaided visual acuity of left eye was 0.02 and corrected visual acuity was 0.2. In addition, there was no recurrence of the endophthalmitis within 1 year of the surgery. The early diagnosis of endogenous fungal endophthalmitis is difficult, and the disease is very likely to be misdiagnosed as uveitis. It is therefore critical to improve awareness of this condition and to reduce the incidence of its misdiagnosis.

Background. Gastric conduit ischemia during esophagectomy. likely contributes to high anastomotic complication. rates, yet we lack a reliable method to assess gastric. conduit perfusion. We hypothesize that optical fiber spectroscopy. (OFS) can reliably assess conduit perfusion and. that the degree of intraoperative gastric ischemia is associated. with subsequent anastomotic complications.. Methods. During esophagectomy, OFS was used to. measure oxygen saturation (SaO2) and blood volume. fraction (BVF) in the distal gastric conduit at baseline. and after gastric devascularization, conduit formation,. and transposition. The SaO2 and BVF readings were. correlated to clinical outcomes.. Results. The OFS measurements were obtained in 23. patients during esophagectomy, four of whom previously. underwent gastric ischemic conditioning. Eight. patients developed anastomotic complications. Compared. with baseline, conduit creation produced a 29.4%. reduction in SaO2 (p , 0.01), while BVF increased by ...

This narrative review aims to evaluate the evidence for the different nutritional approaches employed during neoadjuvant therapy in patients with loco-regional esophageal cancer. Patients with esophageal cancer are often malnourished and difficult to optimise nutritionally. Whilst evidence suggests neoadjuvant therapy can offer a survival advantage, associated toxicity can exacerbate poor nutritional status. There is currently no accepted standard of care regarding optimal nutritional approach.A systematic literature search was undertaken. Studies describing the utilization of an additional nutritional intervention in patients with esophageal cancer receiving neoadjuvant therapy prior to esophagectomy were included. Primary outcome measure was 30-day postoperative mortality after esophagectomy. Secondary outcome measures were loss of weight during neoadjuvant therapy, completion rate of intended neoadjuvant therapy, complications from nutritional intervention, 30-day postoperative morbidity ...

Transhiatal oesophagectomy is an established technique for resection of tumours of the lower oesophagus and oesophagogastric junction. The authors describe a previously unreported serious complication associated with placement of a corrugated neck drain during transhiatal oesophagectomy. A 63 year old man was admitted for transhiatal oesophagectomy for resection of a lower third oesophageal tumour. Post operatively he developed a left sided pneumothorax which did not improve despite numerous chest drains. The subcutaneous corrugated neck drain was removed with immediate inflation of the lung. We report an important potential complication that surgeons in several specialties should be aware of, especially in the use of corrugated neck drains following transhiatal oesophagectomy.

The esophagus is a tube-like gastrointestinal organ located in the chest cavity. It starts from the throat (the pharynx) and is further connected with the stomach.

AIMS: Acute surgical complications after esophageal resection for cancer may decrease the long-term survival. Previous results on this topic are conflicting and no population-based studies are available.. METHODS: A prospective, nationwide Swedish study was conducted in 2001-2010. Eligible patients comprised those afflicted by esophageal or cardia cancer and underwent surgical resection in Sweden in 2001-2005. Details concerning patient and tumor characteristics, surgical procedures, and postoperative surgical complications were collected prospectively. Follow-up for mortality, starting from 90 days after the surgery, was done until May 2010. Cox proportional-hazards regression was performed to estimate hazard ratios (HRs) and 95% confidence intervals (CIs), adjusted for age, tumor stage, sex, histology, comorbidity, surgical approach and surgical radicality.. RESULTS: Among 567 included patients who survived at least 90 days postoperatively, 130 (22.9%) sustained a predefined surgical ...

RESULTS Three hundred thirty-four esophagectomies were performed for 230 adenocarcinomas (202 male, 28 female) and 104 squamous carcinomas (61 male, 43 female). In 9 males and 1 female with adenocarcinomas and 1 male and 1 female with squamous carcinomas, brain metastases developed. Surgical pathology files identified 293 additional esophageal carcinomas, including 2 males with adenocarcinomas metastatic to brain. Tumor registry files identified I additional male with brain metastasis from an undifferentiated esophageal neoplasm. No statistically significant preoperative characteristic of esophageal carcinomas with proneness to brain metastases was found, except large size of primary neoplasm. Preoperative screening head CT done on approximately 240 patients who underwent esophagectomies showed no metastases.. ...

Aspiration is a common finding in the postesophagectomy barium swallow that often necessitates premature termination of the study prior to complete evaluation of the gastric conduit. More importantly, aspiration may play a significant role in the high incidence of postoperative pulmonary complications in this population. The chin tuck maneuver is a postural technique that reduces and often eliminates aspiration in swallowing-impaired patients. To evaluate the ability of the chin tuck maneuver to prevent aspiration during radiographic examination of the gastric conduit, the technique was used in 21 esophagectomy patients who aspirated during a swallowing evaluation combining the barium swallow and videofluoroscopy. Aspiration was eliminated in 81% of aspirators using the chin tuck maneuver. The results of this study demonstrate that the chin tuck maneuver is a simple technique that should be attempted in patients who aspirate postesophagectomy during radiographic imaging studies that require multiple

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Endoscopic therapy offers long-term survival rates similar to those for esophagectomy Researchers in Florida examined national outcomes from endoscopic treatment compared with esophagectomy for 1,619 patients with early-stage esophageal adenocarcinoma. After findings were adjusted for patient and tumor-related factors, overall survival rates were similar.. EQUIP significantly increases adenoma, polyp detection Low adenoma detection rates (ADRs) in colonoscopy are linked to higher colorectal cancer risk. Most attempts to improve them have failed, but a new study shows a significant increase in ADRs after a brief educational intervention.. Opiod-sparing technique associated with reduced progression of prostate tumors Research shows better outcomes in radical prostatectomy patients who had general anesthesia supplemented with spinal or epidural delivery of a long-acting opioid, such as morphine, compared with patients who received general anesthesia only.. ...

Fingerprint Dive into the research topics of Hyperbaric oxygen treatment of hemorrhagic radiation-induced gastritis after esophagectomy. Together they form a unique fingerprint. ...

Radiation therapy alone is as effective in decreasing swallowing complications experienced by advanced esophageal cancer patients as RT combined with chemotherapy, thus allowing patients to forgo chemotherapy, according to research presented today at the American Society for Radiation Oncologys 56th Annual Meeting.

The patient is a 51-year-old male who had undergone robotic Ivor-Lewis esophagectomy with manual anastomosis and hiatal closure around the gastric plasty. No postoperative complications were observed, and the patient was discharged after 11 days. Three days later, he came to the emergency room with sudden abdominal pain and vomiting. Thoracoabdominal radiography and CT scan revealed a transhiatal herniation of the colon with large retrograde dilation (Fig. 1). We decided to perform urgent laparoscopic surgery. After reducing the hernia content, the hiatal orifice was closed and a left chest tube was inserted. The patient evolved favorably and was discharged 4 days after hospitalization. ...

Background Occasionally incurable cancer is encountered after completion of the thoracic (first) phase of a three-phase esophagectomy. The outcome of aborting the operation at this stage, leaving the mobilized thoracic esophagus in situ, is unknown. Methods A multicenter retrospective analysis was performed of patients in whom a completely mobilized thoracic esophagus was left in situ when incurable disease was discovered intraoperatively. The occurrence of esophageal necrosis or perforation, mortality, and all other adverse events were recorded and graded by severity. Results Some 18 patients were included. The median admission time was 9 days. All patients had resumed oral intake at discharge, except for 1 patient who was fed through a nasojejunal tube. After the operation, the median overall survival was 2.9 months. Postoperatively, 7 patients (39%) experienced major surgical adverse events, and 11 patients (61%) had no or only minor adverse events. Major adverse events were associated with ...

Patients who undergo surgery for esophageal cancer have a much higher chance of long-term survival if the surgeon has performed the operation many times before, according to the results of a study published in the Journal of Clinical Oncology.. The esophagus is a muscular tube that food and liquids pass through on their on their way to the stomach. Each year in the United States, more than 17,000 people are diagnosed with cancer of the esophagus and more than 15,000 die of the disease.. Treatment of esophageal cancer often involves esophagectomy, which is surgical removal of the entire esophagus. Although surgery is regarded as the only curative option for resectable esophageal cancer, the procedure carries substantial risks and only one-third of patients survive for five or more years afterward. Some research has indicated that hospital and surgeon volume may impact short-term survival, but few studies have examined the relationship between surgeon volume and long-term survival.. In the most ...

Surgery is an integral part of the treatment of esophageal cancer. However, since esophageal cancer is not exclusively a surgical disease, it is important for patients to be treated at a medical center that can offer multi-modality treatment involving surgeons, gastroenterologists, radiation oncologists, medical oncologists and nutritionists. Removal of the esophagus (esophagectomy) may be utilized…

Oesophageal cancer is a malignant and aggressive disease with very poor survival. The aim of this thesis was to evaluate novel therapeutic targets in oesophageal cancer.. In paper I, Hsp90 was expressed in all 81 oesophageal cancer tissues and also in nine oesophageal cancer cell lines. A specific Hsp90 inhibitor, 17-AAG, could efficiently inhibit cell proliferation, cell survival and sensitise oesophageal cancer cells to gamma photon irradiation. By inhibition of Hsp90 using 17-AAG, EGFR- and IGF-1R-mediated signalling was downregulated.. In paper II, tumour samples from 80 oesophageal cancer patients were investigated for the expression of EGFR and LRIG1-3. Based on a total score of intensity and expression fraction a trend towards survival differences was found for LRIG2 (p=0.18) and EGFR (p=0.09). Correlation analysis revealed a correlation between expression of EGFR and LRIG3 (p=0.0007). Significant correlations were found between LRIG1 mRNA expression levels and sensitivity to cisplatin (r ...

I recently cared for Ms. K, an elderly black woman who had been sitting in the intensive care unit for more than a month. She was, frail, weak and intermittently delirious, with a hopeful smile. She had a big problem: She had undergone an esophagectomy at an outside hospital and suffered a horrible complication, leading her to be transferred to The Johns Hopkins Hospital. Ms. K had a large hole in her posterior trachea, far too large to directly fix, extending from her vocal cords to where her trachea splits into right and left bronchus. She had a trachea tube so she can breathe, and her esophagus was tied off high in her throat so oral secretions containing bacteria did not fall through the hole and infect her heart and lungs. It is unclear if she will survive, and the costs of her medical care will be in the millions.. Ms Ks complication is tragic-and largely preventable. For the type of surgery Read more ». ...

Experts indicate that omitting LND could have advantages in terms of fewer complications and shorter OR time, thereby improving quality of life and reducing costs. Currently, it is unknown if these advantages will weigh up to the possible risks of omitting LND when a diagnostic test is not 100% accurate. Recently, two phase III trials were initiated where watchful waiting is compared with standard surgery for patients with complete response of the tumour and LNs after nCRT.23 24 In these trials, the importance of an accurate diagnostic test after nCRT is crucial as patients with (micro) LN metastases could easily be missed, resulting in unjustified omission of surgery. Results of these trials are therefore of high interest to evaluate the consequences of unjustified omission of surgery.. The implications of accurate LN staging after nCRT will likely have a greater impact than solely omitting LND. For example, surgical approaches with a limited LND, for example, transhiatal oesophagectomy, might ...

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An esophageal cancer is a cancerous growth in the food pipe, which runs from the throat to the stomach. Chemotherapy & Radiation therapy are the most preferred treatment options for Esophageal Cancer.

From esophageal cancer prevention and management tips to caregiving for loved ones with the disease, learn more in EverydayHealths Esophageal Cancer Center.

What is Esophageal Cancer? Get the facts about Esophageal Cancer symptoms, testing, treatment and care options from trusted sources.

What is Esophageal Cancer? Get the facts about Esophageal Cancer symptoms, testing, treatment and care options from trusted sources.

Esophageal cancer symptoms include fatigue, weakness, ache all over, vomiting, sharp abdominal pain, and difficulty in swallowing. Doctors that see patients with esophageal cancer specialize in primary care.

Esophageal cancer (esophageal carcinoma) is cancer that occurs in the esophagus which connects the mouth to the stomach. It is a rare type of cancer, but can be very aggressive.

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Emergency physician, blogger (ivor-kovic.com), innovator (ivormedical.com), researcher (researchgate.net/profile/Ivor_Kovic), speaker (youtu.be/Q-E-B3Pc8mk ...

Meet Dr. Ivor Foox MD, a Family Medicine Doctor in 18300 Katy Fwy Ste 615, . Find phone number, office address, bio, maps and more.

The stage of a cancer is how much and how far the cancer has spread in your body. The most commonly used system to stage esophageal cancer is called the TNM classification.

Half of patients with metastatic esophageal cancer responded to a regimen of conventional chemotherapy and erlotinib (Tarceva), investigators in a small clinical trial reported here.

Oesophageal cancer is a very serious type of cancer that can prove to be fatal if it is not diagnosed at an early stage. Learn details here.

Learn more about Diagnosis of Esophageal Cancer at Grand Strand Medical Center Main Page Risk Factors ...