TY - JOUR. T1 - Complete Nucleotide Sequence of an Escherichia coli Sequence Type 410 Strain Carrying blaNDM-5 on an IncF Multidrug Resistance Plasmid and blaOXA-181 on an IncX3 Plasmid. AU - Overballe-Petersen, Søren. AU - Roer, Louise. AU - Ng, Kim Lee. AU - Hansen, Frank. AU - Justesen, Ulrik Stenz. AU - Andersen, Leif P. AU - Stegger, Marc. AU - Hammerum, Anette M. AU - Hasman, Henrik. PY - 2018. Y1 - 2018. N2 - Using Nanopore sequencing, we describe here the circular genome of an Escherichia coli sequence type 410 (ST410) strain with five closed plasmids. A large 111-kb incompatibility group F (IncF) plasmid harbored blaNDM-5 and 16 other resistance genes. A 51-kb IncX3 plasmid carried QnrS1 and blaOXA-181. E. coli isolates with both blaNDM-5 and blaOXA-181 carbapenemases are rare.. AB - Using Nanopore sequencing, we describe here the circular genome of an Escherichia coli sequence type 410 (ST410) strain with five closed plasmids. A large 111-kb incompatibility group F (IncF) plasmid ...
ICD-10 A04.1 is enterotoxigenic escherichia coli infection (A041). This code is grouped under diagnosis codes for certain infectious and parasitic diseases.
Synonyms for Escherichia coli infections in Free Thesaurus. Antonyms for Escherichia coli infections. 1 synonym for Escherichia coli: E. coli. What are synonyms for Escherichia coli infections?
Looking for Escherichia coli infections? Find out information about Escherichia coli infections. common bacterium that normally inhabits the intestinal tracts of humans and animals, but can cause infection in other parts of the body, especially the... Explanation of Escherichia coli infections
Extraintestinal pathogenic Escherichia coli (ExPEC) strains of serotype O1:K1:H7/NM are frequently implicated in neonatal meningitis, urinary tract infections and septicemia in humans. They are also commonly isolated from colibacillosis in poultry. Studies to determine the similarities of ExPEC from different origins have indicated that avian strains potentially have zoonotic properties. A total of 59 ExPEC O1:K1:H7/NM isolates (21 from avian colibacillosis, 15 from human meningitis, and 23 from human urinary tract infection and septicemia) originated from four countries were characterized by phylogenetic PCR grouping, Multilocus Sequence Typing (MLST), Pulsed Field Gel Electrophoresis (PFGE) and genotyping based on several genes known for their association with ExPEC or avian pathogenic Escherichia coli (APEC) virulence. APEC and human ExPEC isolates differed significantly in their assignments to phylogenetic groups, being phylogroup B2 more prevalent among APEC than among human ExPEC (95% vs. 53%, P =
Looking for Enteroaggregative Escherichia Coli? Find out information about Enteroaggregative Escherichia Coli. common bacterium that normally inhabits the intestinal tracts of humans and animals, but can cause infection in other parts of the body, especially the... Explanation of Enteroaggregative Escherichia Coli
TY - JOUR. T1 - Role of virulence factors on host inflammatory response induced by diarrheagenic Escherichia coli pathotypes. AU - Sanchez-Villamil, Javier. AU - Navarro-Garcia, Fernando. PY - 2015/1/1. Y1 - 2015/1/1. N2 - Pathogens are able to breach the intestinal barrier, and different bacterial species can display different abilities to colonize hosts and induce inflammation. Inflammatory response studies induced by enteropathogens as Escherichia coli are interesting since it has acquired diverse genetic mobile elements, leading to different E. Coli pathotypes. Diarrheagenic E. Coli secrete toxins, effectors and virulence factors that exploit the host cell functions to facilitate the bacterial colonization. Many bacterial proteins are delivered to the host cell for subverting the inflammatory response. Hereby, we have highlighted the specific processes used by E. Coli pathotypes, by that subvert the inflammatory pathways. These mechanisms include an arrangement of pro- and anti-inflammatory ...
We examined extended-spectrum β-lactamase-producing isolates from livestock, humans, companion animals, food, and the environment during 2009-2016 in Germany for the presence of CTX-M-27 allele within Escherichia coli sequence type (ST) 131. E. coli ST131 C1-M27 was exclusively present in humans; its incidence increased from 0% in 2009 to 45% in 2016.
Escherichia coli bacteria cause many illnesses of the gastrointestinal tract. Often, people come down with these diseases when they eat contaminated foods, especially ground beef or raw produce. Though E. coli infections are most common in less developed parts of the world, they are also a problem in the United States-contamination occurred in prepackaged cookie dough in 2009 and in spinach in 2006. But all E. coli are not harmful, as strains found in the human intestinal system can help with vitamin K production or in fighting harmful bacteria. This revised edition of Escherichia coli Infections contains up-to-date information on the different strains of E. coli, including the latest outbreaks, statistics, diagnostic breakthroughs, and vaccine development ...
TY - JOUR. T1 - Diarrheagenic Escherichia coli and Virulence Determinants. AU - Okamoto, Keinosuke. AU - Yamanaka, Hiroyasu. AU - Fujii, Yoshio. PY - 1991/1/1. Y1 - 1991/1/1. N2 - Escherichia coli is normally the most common facultative anaerobe in the large bowel and usually nonpathogenic for man. However, some E. coli strains which cause distinct syndromes of diarrhea diseases have been proved to be pathogenic. These organisms are one of the most common causes of food poisoning in Japan. In developing countries, these pathogens are known to be main causative agents of diarrhea which is the major cause of infantile morbidity and mortality. These E. coli strains are divided into four groups: enteropathogenic E. coli (EPEC), enter-oinvasive E. coli (EIEC), enterotoxigenic E. coli (ETEC), and enterohemorrhagic E. coli (EHEC). The four groups are distinguished on the basis of pathogenic, clinical, and epidemiologic features. Moreover, the fifth group of diarrheagenic E. coli, termed ...
Thank you for sharing this Antimicrobial Agents and Chemotherapy article.. NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.. ...
Presence and characterization of extraintestinal pathogenic Escherichia coli (ExPEC) virulence genes in F165-positive E. coli strains from diseased calves and pigs
When both glucose and lactose are present in the growth medium, the uptake of lactose is strongly inhibited by glucose because of an increase in the nonphosphorylated form of IIAGlc, an inhibitor of lac permease. Mechanism responsible for glucose-lactose diauxie in Escherichia coli - challenge to the cAMP model
Eight newborn calves were challenged orally with a known enteropathogenic strain of Escherichia coli 0101 K?(A) and two to six hours later each calf was fed a minimum of three pints colostrum. All calves suffered from acute diarrhoea of varying severity within 24 to 48 hours of infection. Immunofluorescent and histological examination of the small intestine demonstrated adherence of the challenge organism to the epithelium and the presence of pathological lesions similar to those seen in colostrum-deprived calves with enteric colibacillosis. It was concluded that in order to be effective prophylactically, colostrum must be fed prior to infection.. ...
Although Escherichia coli infections are common throughout the developing world, their prevalence patterns in space and over time are not well characterized. We used serial case control data collected from 16 communities in northwestern Ecuador between 2004 and 2010, to examine the prevalence of enteroinvasive E. coli (EIEC) and enterotoxigenic E. coli (ETEC). At its peak, the regional prevalence of EIEC was 8.3 infections/100 persons but this decreased to 1 infection/1,000 persons. The regional prevalence of ETEC ranged from 8 infections/1,000 persons to 3.7 infections/100 persons. The prevalence pattern of EIEC resembled that of a large epidemic whereas the prevalence Although Escherichia coli infections are common throughout the developing world, their prevalence patterns in space and over time are not well characterized. We used serial case control data collected from 16 communities in northwestern Ecuador between 2004 and 2010, to examine the prevalence of enteroinvasive E. coli (EIEC) and ...
Synonyms and Keywords: Colibacillosis, E. coli enteritis, E. coli gastroenteritis, E. coli colitis, E. coli dysentery, E. coli diarrhea, Diarrheagenic E. coli infection, ETEC (toxigenic E. coli) infection, EHEC (enterohemorrhagic E. coli) infection, STEC (Shiga-like toxin producing E. coli), VTEC (Veratoxin-producing E. coli), EPEC (enteropathogenic E. coli) infection, EAEC (enteroaggregative E. coli) infection, EIEC (enteroinvasive E. coli) infection, DAEC (diffusely adherent E. coli) infection ...
Risk Assessment of Escherichia coli Infection from Use of Interactive Waterscape Facilities - Escherichia coli;Exposure;Interactive fountain;Risk assessment;
The intimin gene eae, located within the locus of enterocyte effacement pathogenicity island, distinguishes enteropathogenic Escherichia coli (EPEC) and some Shiga toxin-producing E. coli (STEC) strains from all other pathotypes of diarrheagenic E. coli. EPEC is a leading cause of infantile diarrhea in developing countries, and intimin-positive STEC isolates are typically associated with life-threatening diseases such as hemolytic-uremic syndrome and hemorrhagic colitis. Here we describe the development of a PCR-restriction fragment length polymorphism (RFLP) assay that reliably differentiates all 11 known intimin types (α1, α2, β, γ, κ, ɛ, η, ι, λ, θ, and ζ) and three new intimin genes that show less than 95% nucleotide sequence identity with existing intimin types. We designated these new intimin genes Int-μ, Int-ν, and Int-ξ. The PCR-RFLP assay was used to screen 213 eae-positive E. coli isolates derived from ovine, bovine, and human sources comprising 60 serotypes. Of these, 82 were
Learn more about Escherichia coli Infection at Medical City Dallas DefinitionCausesRisk FactorsSymptomsDiagnosisTreatmentPreventionrevision ...
The Report Escherichia coli Infections Global Clinical Trials Review, H2, 2016 provides information on pricing, market analysis, shares, forecast, and...
Enteropathogenic E. coli (EPEC) and enterohemorrhagic E. coli (EHEC) are closely related pathogenic strains of Escherichia coli. The hallmark of EPEC/EHEC infections [DS:H00278 H00277] is induction of attaching and effacing (A/E) lesions that damage intestinal epithelial cells. The capacity to form A/E lesions is encoded mainly by the locus of enterocyte effacement (LEE) pathogenicity island. Tir, Map, EspF, EspG are known LEE-encoded effector proteins secreted via the type III secretion system, which is also LEE-encoded, into the host cell. EPEC and EHEC Tirs link the extracellular bacterium to the cell cytoskeleton. Map and EspF are involved in mitochondrion membrane permeabilization. EspG interacts with tubulins and stimulates microtubule destabilization. LEE-encoded adhesin or intimin (Eae) is exported via the general secretory pathway to the periplasm, where it is inserted into the outer membrane. In addition to Tir, two potential host cell-carried intimin receptors, beta1 integrin (ITGB1) ...
Urinary tract infection (UTI) is the most common form of extraintestinal Escherichia Coli infection (E.coli), and E. coli is the most common cause of UTI.The aim of this paper is to study the uropathogenicity factors for some strains of E.coli involved in the etiology of UTI and the affiliationof urinary E.coli strains to the serogroups involved in the UTI.We studied 208 strains of E. coli from urine samples sterilely collected from patients with clinical suspicion of urinary tract infection.The study was conducted in Emergency County Hospital Craiova between 2012-2014.Out of the 208 strains of E. coli submitted to the study, 60 strains (28.84%) - MRHA with human red cells, 28 strains (13.50%) - MRHA human red cells and blood red cells MSHA with guinea pigs, and 44 strains (21.12%) - MSHA with guinea pig red blood cells; 76 strains (36.54%) - no hemagglutination. Regarding our study, 42,34% of E.coli strains presented human MRHA putting forward their potential to cause pyelonephritits. The 68
Escherichia coli colonizes the human intestine shortly after birth, with most strains engaging in a commensal relationship. However, some E. coli strains have evolved toward acquiring genetic traits associated with virulence. Currently, five categories of enteroadherent E. coli strains are well-recognized, and are classified in regard to expressed adhesins and the strategy used during the colonization. The high morbidity associated with diarrhea has motivated investigations focusing on E. coli adhesins, as well on factors that inhibit bacterial adherence. Breastfeeding has proved to be the most effective strategy for preventing diarrhea in children. Aside from the immunoglobulin content, glycocompounds and oligosaccharides in breast milk play a critical role in the innate immunity against diarrheagenic E. coli strains. This review summarizes the colonization factors and virulence strategies exploited by diarrheagenic E. coli strains, addressing the inhibitory effects that oligosaccharides and
The term enteropathogenic Escherichia coli was originally used to refer to strains belonging to a limited number of O groups epidemiologically associated with infantile diarrhea ( 1 ). Subsequently, E. coli strains isolated from intestinal diseases have been grouped into at least six main categories on the basis of epidemiological evidence, phenotypic traits, clinical features of the disease they produce, and specific virulence factors. The well-described intestinal pathotypes or categories of diarrheagenic E. coli groups are enteropathogenic E. coli (EPEC), Shiga toxin-producing E. coli (STEC) or verocytotoxin-producing E. coli (VTEC) (including enterohemorrhagic E. coli [EHEC]), enterotoxigenic E. coli (ETEC), enteroaggregative E. coli (EAEC), enteroinvasive E. coli, and diffusely adherent E. coli. The general definition of an E. coli pathotype as "a group of strains of a single species that cause a common disease using a common set of virulence factors" ( 2 ) has been further refined for STEC ...
E. coli possesses four iron uptake systems that use siderophores such as enterobactin and aerobactin, produced by E. coli, or the fungal siderophores ferrichrome and coprogen. Iron acquisition by this bacterium can also occur in a process mediated by citrate ((1), (5)). Pathogenic E. coli strains are able to use heme compounds as iron sources, but so far little is known about the mechanisms involved in this kind of iron uptake ((10)). The results of this study suggest that the human pathogenic E. coli strain EB1 contains a hemophore-dependent heme acquisition system. The bacterium secretes a heme-binding protein (Hbp) with an estimated size of 110 kD, that degrades hemoglobin. It is likely that Hbp is the shuttle protein of this heme-scavenging system in E. coli.. Recently, an exported protease (PssA) from a Shiga toxin-producing E. coli has been characterized ((43)). Sequence comparison showed that PssA is related to the family of autotransporter proteins, especially to SepA of S. flexneri ...
E. coli is a type of gram negative bacteria that lives in the gastrointestinal tract of people and animals. Some E. coli bacteria strains in contaminated food and water can cause diarrhea, urinary tract infections and abdominal cramps.
PubMed comprises more than 30 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
34. 35. . Bursitis sternalis (inflammation of the sternal bursa). The bursa is enlarged in a various extent and filled with inflammatory exudate. The diagnosis of coli - infections is based on isolation and typization of pathogenic E. coli serotypes. Many other bacteria (salmonellae, pasteurellae, staphylococci etc.), viruses, chlamydiae and mycoplasmae should be excluded as possible aetiological agents. The prevention should aim at minimizing the probability of faecal contamination of eggs. This implies the maintenance of clean nests, discarding floor eggs and removal of eggs that are cracked or contaminated with faeces. Breeder eggs should be fumigated or disinfected in the farm prior to their transportation in the storage premise. The treatment is effective if initiated soon after testing the antibacterial sensitivity of isolates ...
A human challenge model was developed to study nutritional interventions to prevent infection with diarrhoeagenic Escherichia coli, one of the major and most common causes of diarrhea. Challenges with high doses of E. coli was shown to prevent clinical symptoms upon re-infection. Here we aimed to study if a low dose primary E. coli challenge induced only partial protection against re-infection. Thirty healthy male volunteers were selected,randomized, and orally exposed to increasing concentrations of E. coli strain E1392/75-2A(10e6, 10e7, 10e8, 10e9, and 10e10 CFU). Clinical symptoms of gastrointestinal discomfort were recorded, and stool and blood samples were collected. These were analyzed for immunological responses, stool characteristics, and inflammatory markers. After primary infection,E. coli-specific serum IgG(CFA/II) titers increased in a dose-dependent manner.Three weeks later, all volunteers were re-infected with a high E. coli dose(10e10 CFU). Surprisingly,all primary E. coli doses ...
Uropathogenic E. coli are paradoxically able to both cause disease in the urinary tract, and reside there asymptomatically. The pandemic, multi-drug resistant E. coli subclone ST131-H30 (H30) is of special interest, as it has been found to persist in the gut and bladder of healthy people. In order to understand this persistence, we investigated whether H30 is competitive in these niches and thus able to persist by excluding other E. coli, as well as whether H30 may persist via within-host adaptation. In order to assess the E. coli clonal landscape, we developed a novel method based on deep sequencing of two loci, along with an algorithm for analysis of resulting data. Using this method, we assessed fecal and urinary samples from healthy women carrying H30, and found that even in the absence of antibiotic use, H30 could completely dominate the gut and, especially, urine of healthy carriers. In order to ascertain whether H30 adapts within host, we employed population-level whole genome sequencing, ...
General Information:. Escherichia coli (E. coli) are gram negative, facultatively anaerobic rod bacteria which move by peritrichal flagellation and belong to the Enterobacteriaceae family. E. coli are part of the normal intestinal flora of humans and many farm animals and are generally apathogenic. Some E. coli strains are pathogenic to humans through the acquisition of certain virulence factors (eg., genes for toxins). The six known intestinal pathogenic E. coli: enterohämorrhagic E. coli(EHEC), enteropathogeic E. coli (EPEC), enterotoxic E. coli (ETEC), enteroinvasive E. coli (EIEC), EAEC enteroaggregative E. coli und diffusely adherent E. coli (DAEC) can be differentiated by the virulence factors. Enterohämorrhagic E. coli (EHEC) are currently the most important intestinal pathogenic E. coli. EHEC are a subgroup of the Shiga toxin or Verotoxin producing E. coli (STEC or VTEC) and are capable to produce two cytotoxins, Verotoxin 1 and 2. Due to the similarity of the Verotoxins to the Shiga ...
Efforts to treat Escherichia coli infections are increasingly being compromised by the rapid, global spread of antimicrobial resistance (AMR). Whilst AMR in E. coli has been extensively investigated in resource-rich settings, in sub-Saharan Africa molecular patterns of AMR are not well described. In this study, we have begun to explore the population structure and molecular determinants of AMR amongst E. coli isolates from Malawi. Ninety-four E. coli isolates from patients admitted to Queens Hospital, Malawi, were whole-genome sequenced. The isolates were selected on the basis of diversity of phenotypic resistance profiles and clinical source of isolation (blood, CSF and rectal swab). Sequence data were analysed using comparative genomics and phylogenetics. Our results revealed the presence of five clades, which were strongly associated with E. coli phylogroups A, B1, B2, D and F. We identified 43 multilocus STs, of which ST131 (14.9%) and ST12 (9.6%) were the most common. We identified 25 AMR ...
Overview of Enterotoxigenic E. Coli infection as a medical condition including introduction, prevalence, prognosis, profile, symptoms, diagnosis, misdiagnosis, and treatment
The Lens serves almost all the patents and scholarly work in the world as a free, open and secure digital public good, with user privacy a paramount focus.
CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): This article cites 40 articles, 26 of which can be accessed free
BioAssay record AID 425583 submitted by ChEMBL: Antibacterial activity against Escherichia coli isolate HM605 isolated from colonic mucosal biopsies of patient with Crohns disease.
To determine the origin of >4,000 suspected diarrheagenic Escherichia coli strains isolated during 2004-2011 in South Africa, we identified 7 isolates as serotype O104; 5 as enteroaggregative E. coli O104:H4, and 2 as enteropathogenic E. coli O104:no ...
Some of the worlds top scientists are gathering at Penn State next week for an invitation-only workshop to discuss how to reach a consensus on techniques to identify new serotypes of E. coli. Penn States 50-year-old E. coli Reference Center is hosting the international meeting. "We hope the workshop here can lead to a consensus," said… Continue Reading. ...
Townes, Claire L, Ali, Ased, Gross, Naomi, Pal, Deepali, Williamson, Stuart, Heer, Rakesh, Robson, Craig N, Pickard, Robert S and Hall, Judith (2013) Prostate specific antigen enhances the innate defence of prostatic epithelium against Escherichia coli infection. The Prostate, 73 (14). pp. 1529-1537. ISSN 0270-4137 ...
Also called: Escherichia coli E. coli is the name of a type of bacteria that lives in your intestines. Most types of E. coli are harmless. However,...
Godaly, G et al "Role of epithelial interleukin-8 (IL-8) and neutrophil IL-8 receptor A in Escherichia coli-induced transuroepithelial neutrophil migration.." Infection and Immunity 65.8 (1997): 3451-3456. Web. 29 Feb. 2020. ...
E coli is a common bacteria found inside of people and animals intestines. it is also found in the environment and in food. But certain types (strains) of E coli are harmful and can cause severe illness in people. You or your child can be infected by swallowing food or water that contain the bacteria. Contamination occurs when food or water comes in contact with stool from infected humans and animals.
Children dominate the list of 41 case patients associated with the Milk Makers Fest E. coli outbreak attended by Whatcom County first graders in Washington
Despite ongoing public health efforts, E. coli outbreaks continue to infiltrate the food supply, annually causing significant sickness and death throughout the
by Heike Ewing Ott Is E. Coli dangerous to Parrots? How do we as bird owners minimize that risk? This article, written by an experienced bird breeder, takes a
All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this items handle: RePEc:oup:erevae. See general information about how to correct material in RePEc. For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: (Oxford University Press). General contact details of provider: http://edirc.repec.org/data/eaaeeea.html ...
All material on this site has been provided by the respective publishers and authors. You can help correct errors and omissions. When requesting a correction, please mention this items handle: RePEc:cca:wplabo. See general information about how to correct material in RePEc. For technical questions regarding this item, or to correct its authors, title, abstract, bibliographic or download information, contact: (Giovanni Bert). General contact details of provider: http://edirc.repec.org/data/fccaait.html ...
Signs and symptoms of an E. coli infection include bloody diarrhea, abdominal cramping and pain and, in some people, nausea and vomiting. These symptoms usually begin three to four days after...
Colibacillosis affects pigs worldwide, and is considered a major health problem due to its pathogenicity. The disease involves a high economic impact due to increase in mortality, stunting, poor feed conversion, and additional costs due to medication. Vaccination and antibiotic therapies are commonly used for treatment and control of colibacillosis. However, the levels of resistance observed in E. coli to commonly used antibiotics, has been increasing over time in most pig rearing areas.. ...
Colibacillosis affects pigs worldwide, and is considered a major health problem due to its pathogenicity. The disease involves a high economic impact due to increase in mortality, stunting, poor feed conversion, and additional costs due to medication. Vaccination and antibiotic therapies are commonly used for treatment and control of colibacillosis. However, the levels of resistance observed in E. coli to commonly used antibiotics, has been increasing over time in most pig rearing areas.. ...