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TY - JOUR. T1 - Development of a new 3-DOF parallel manipulator for minimally invasive surgery. AU - Khalifa, Alaa. AU - Fanni, Mohamed. AU - Mohamed, Abdelfatah M.. AU - Miyashita, Tomoyuki. PY - 2018/6/1. Y1 - 2018/6/1. N2 - This article proposes a novel dexterous endoscopic parallel manipulator for minimally invasive surgery. The proposed manipulator has 3 degrees of freedom (3-DOF), which consist of two rotational DOFs and one translational DOF (2R1T DOFs). The manipulator consists of 3 limbs exhibiting identical kinematic structure. Each limb contains an active prismatic joint followed by 2 consecutive passive universal joints. The proposed manipulator has a unique arrangement of its joints axes. This unique arrangement permits large bending angles, ±90° in any direction, and a workspace almost free from interior singularities. These advantages allow the proposed manipulator to outperforms existing surgical manipulators. However, this unique arrangement makes the analysis of the robot ...

Field programmable gate arrays (FPGAs) represent the currently the most popular and also the newest media for designing application specific integrated digital circuits. They contain an array of a large number of programmable sequential and combinational logic elements (called gates, logic blocks or look up tables). The array of such logic blocks, literally a sea of them, is distributed across a digital chip through interconnections that are programmable. This array is surrounded by a programmable input/output blocks ...

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Control apparatus for manipulator welding apparatus is provided that includes a vision correction system for workpiece sensing. During an initial teach mode, the manipulator is taught the desired welding path on a workpiece by the appropriate recording of data representing the welding path as an operator controls movement of the manipulator. In addition to the data representing the taught welding path, data representing a reference image or template is also recorded in the teach mode. The reference image or template data is provided by a vision system including a camera carried by the manipulator arm. As successive workpieces are presented to the manipulator for performing the desired welding path, in a repeat work cycle mode the manipulator is controlled to move in accordance with the recorded taught data in a first repeat pass wherein images of the welding seam region are detected at successive points. The vision system utilizing an image processor detects the deviation between the taught welding path

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TY - CHAP. T1 - Modeling light-tissue interaction in optical coherence tomography systems. AU - Andersen, Peter E.. AU - Jørgensen, Thomas Martini. AU - Thrane, Lars. AU - Tycho, Andreas. AU - Yura, H. T.. PY - 2015. Y1 - 2015. KW - Absorption. KW - Light propagation. KW - Light tissue interaction. KW - Optical coherence tomography. KW - Scattering. KW - Theoretical model. U2 - 10.1007/978-3-319-06419-2_4. DO - 10.1007/978-3-319-06419-2_4. M3 - Book chapter. SN - 978-3-319-06418-5. SP - 95. EP - 140. BT - Optical coherence tomography. A2 - Drexler, W.. A2 - Fujimoto, J.G.. PB - Springer. ER - ...

TY - JOUR. T1 - A contour-mode film bulk acoustic resonator of high quality factor in a liquid environment for biosensing applications. AU - Xu, Wencheng. AU - Choi, Seokheun. AU - Chae, Junseok. PY - 2010/2/17. Y1 - 2010/2/17. N2 - This letter reports an acoustic resonator of high quality factors (Qs) operating in liquid media. The film bulk acoustic resonator (FBAR) is made of a ring-shaped piezoelectric aluminum nitride thin film, and is excited in a contour mode. By having a low motional resistance upon coupling with liquids, the contour mode FBAR achieved Qs up to 189, more than 12× over the state-of-the-art FBARs in liquids. The resonator was characterized by an aptamer-thrombin binding pair for a biosensor and showed a mass resolution of 1.78 ng/ cm2.. AB - This letter reports an acoustic resonator of high quality factors (Qs) operating in liquid media. The film bulk acoustic resonator (FBAR) is made of a ring-shaped piezoelectric aluminum nitride thin film, and is excited in a contour ...

Changing water quality was prevalent in the current water supply. The fluctuation of iron stability due to changing water quality followed four characteristics: objectivity, relativity, predictability, and controllability. Therefore, it was necessary to study the stability of iron in the pipe network by integrating different water quality factors. The iron stability risk evaluation system was established according to the different water quality factors in the drinking water distribution systems (DWDSs). Meanwhile, an improved fuzzy comprehensive evaluation method was established to evaluate the risk of iron. Chloride, sulfate, dissolved organic matter (DOM) and pH were selected as the risk assessment index. The divisions of different evaluation levels were carried out through the values of water quality factor. On the basis of expert scoring, the weight and membership degree of water quality factors were analyzed by structural entropy method. In addition, risk analysis was established by using the

0070] Delivery catheter 16 is then pulled back (in a proximal direction) until an end portion 15 thereof is positioned against the inner artery wall at access site hole 22 (FIG. 3). Distal portion 15 is pivotally attached and thus can angle and align with the longitudinal axis of artery 12 to facilitate deployment of expandable device 18 described below. Delivery catheter also includes an inspection hole 17 for indicating correct positioning of distal portion 15 of delivery catheter 16 within artery 12. Such an indication can be provided by stoppage of blood dripping from inspection hole 17 when delivery catheter is correctly positioned. To enable such functionality inspection hole 17 is fluidly connected to a conduit which terminates at a distal region of delivery catheter 16. When that distal region of delivery catheter is positioned within artery 12, the conduit communicates blood flowing through artery 12 to inspection hole 17, however, when delivery catheter is pulled back to a position in ...

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Early diagnostic and treatment of prostate cancer could be achieved using magnetic resonance imaging (MRI) to improve tumor perceptibility. Nonetheless, performing intra-MRI interventions present significant challenges due to intense magnetic fields and limited patient access. This paper presents an MRI-compatible manipulator using elastically averaged binary pneumatic air muscles (PAMs) to orient a needle into a targeted region of the prostate under the command of a physician. The proposed manipulator is based on an all-polymer compliant mechanism designed to make a completely MRI-compatible positioning system. A model based on the PAMs deformation energy is used to design the manipulator so that its discrete workspace, stiffness, and size meet clinically relevant design requirements. The model is also used to study the motion of the device during a state shift. A laboratory prototype of the device shows that the covered workspace, stiffness, and size of the manipulator can meet clinical ...

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Additive manufacturing is widely used in the meantime for medical device developments. Specially the BioDesign process with strong user integration and feedback loops benefits from fast prototyping. In this work, an innovative conceptual design of revolving biopsy needle is CAD modelled using SolidWorks software and subsequently 3D printed. The material properties of the resins were fit to use for fabrication of the different mechanisms that the prototype requires. 3D printing is a very good method of quickly checking different design ideas, to present functionalities to clinical partners, to optimize and define the ideal design. Even delicate structures are possible.. ...

INTENDED USE/INDICATIONS FOR USE. The Maestro 4000 Cardiac Ablation System is intended for use with BSC cardiac ablation catheters in cardiac ablation procedures.. Note: Refer to the individual catheter Directions for Use for catheter compatibility to the Maestro 4000 Cardiac Ablation System. It is also important to carefully review the specific indications, contraindications, warnings, precautions and adverse events included with each catheter, prior to use of the catheter with the Maestro 4000 Cardiac Ablation System.. CONTRAINDICATIONS. There are no specific contraindications for use of the Maestro 4000 Cardiac Ablation System itself. However, users should read and understand the specific indications, contraindications, warnings, and precautions included with any cardiac ablation catheter used in conjunction with the System.. Note: The contraindications listed in the catheter Directions For Use also apply to the use of the Maestro 4000 Cardiac Ablation System. Carefully review the specific ...

Robots are becoming increasingly more common in the industry. In order to expand the use of robotic manipulators to complex tasks, a higher degree of tailoring of robots may be required. Tailoring of the mechanical design of a robot manipulator can be formulated as an optimization problem and we propose to use Genetic Algorithms (GA) to optimize link lengths, link diameters, and link thickness in order to determine the robot design for a given fitness function. As a case, the optimization of a robot manipulator for automated cleaning of fish processing plants is presented. For this application, the kinematic layout and joint configuration are decided beforehand. The dynamics of the robotic manipulator are presented along with the optimization algorithm and implemented in Java. Results show that the GA is well suited for the optimization of the design ...

The present invention relates to a catheter, a manipulator and a combination thereof. In the wall (7) of the catheter a pull line (8) is slideably mounted. The proximal end of the pull line is fastened in an inner spindle (14) of a manipulator and the distal end of the pull line is fastened at an X-ray marker in the distal end of the catheter (1). During axial movement of the setting means (11) of the manipulator this movement is transmitted to the distal end portion of the catheter, whereby a relatively large movement of the setting means (11) is shifted down to a smaller movement of the end portion of the catheter via the adjusting sleeve (15) and spindle (14) of the manipulator. The position set by the setting means (11) is irreversible and the catheter (1) shows twisting strength.

All future combustion and electric powered automobiles will be equipped with sensors directly interfaced with control electronics. The control and power electronics for combustion engines will have to cope with high temperatures and adverse environments. Hybrid and electric vehicles require new device technology to handle the high power in their distribution and control systems. High efficiency, low weight and elevated temperature operation electronics will be critical. Because of its unique physical and electronic properties, silicon carbide is an ideal semiconductor for both high temperature and high power applications. Yet despite SiCs promise, little attention has been paid to the optimization of device designs for high power application. We propose to address a key power device design requirement, minimization of parasitic effects which limit performance, and thereby demonstrate the superiority of SiC devices. ATMs expertise in high purity SiC substrates and epitaxial growth will be ...

planar parallel manipulator with similar triangular platforms. Although it has been revealed numerically elsewhere that for this parallel manipulator, the four solutions to the FDA fall, respectively, into its four singularity-free regions (in its workspace), it is unclear if there exists a one-to-one correspondence between the four formulas, each producing one solution to the FDA, and the four singularity-free regions. Using an algebraic approach, this paper will prove that such a one-to-one correspondence exists. Therefore, a unique solution to the FDA can be obtained in a straightforward way for such a parallel manipulator if the singularity-free region in which it works is specified. ...

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Devices employed in electrical policing rely on fundamental responses of nerve and muscle to supraphysiologic current to quell disruptive behavior. Whilst widely deployed the use of neuromuscular incapacitation (NMI) remains controversial, in part, due to gaps in understanding of the underlying mechanisms related to injury. NMI device manufacturers are thus constrained by empirical evidence for safety and effectiveness for a specific device design. Here we examine published data for several NMI devices considering ex vivo signal characteristics and in vivo responses in relation to effectiveness and injury. The sensitivity of lactate production to NMI device signal frequency (Hz) and macro-dosimetry is explored as a primary device design factor in NMI modes of injury. The non-lethal approach to policing regardless of technology will result in fatalities due to compromised health and substance abuse status unknowable at the time of NMI application. Thus, research to establish a science-based understanding

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The INDEED network is a €4 million Marie Skłodowska-Curie Actions- Innovative Training Network (ITN) - project funded by the European Commission, under the H2020 program and coordinated by Durham University. INDEED is a consortium of 11 Universities and 2 industrial companies, together with 13 associate industry partners across Europe.. The main scientific objective is to translate semiconductor nanowire (NW) technology concepts into market-ready products. As such, the scientific programme is directed towards customer-oriented R&D and exploits innovative industrial design techniques to ensure rapid translation of the basic technologies into commercial devices.. ...

George Ions dissects the different factors that will determine biosimilars adoption and pace of advancement against their original counterparts, namely clinical confidence in the biosimilar and patient confidence in the drug delivery device.

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STUDY DESIGN: Reliability and case-control injury study.OBJECTIVES: To determine if a novel device designed to measure eccentric knee flexor strength via the Nordic hamstringexercise displays acceptable test-retest reliability; to determine normative values for eccentric knee flexor strength derived from the device in individuals without a history of hamstringstrain injury (HSI); and to determine if the device can detect weakness in elite athletes with a previous history of unilateral HSI.BACKGROUND: HSI and reinjury are the most common cause of lost playing time in a number of sports. Eccentric knee flexor weakness is a major modifiable risk factor for future HSI. However, at present, there is a lack of easily accessible equipment to assesseccentric knee flexor strength.METHODS: Thirty recreationally active males without a history of HSI completed the Nordic hamstring exercise on the device on 2 separate occasions. Intraclass correlation coefficients, typical error, typical error as a ...

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An endoprosthesis delivery catheter assembly comprises a placement catheter having first and second catheter shafts. A handle includes a body and an actuator mounted to the body for movement relative to the body. The proximal portions of the first and second catheter shafts are mounted to the handle. At least one of the proximal portions of the first and second catheter shafts are drivenly coupled to the actuator so that movement of the actuator causes rotary and/or axial movement of the first and second catheter shafts relative to one another. The actuator may be mounted to the body for both rotary and axial movement relative to the body so that rotary and axial movement of the actuator causes corresponding relative rotary and axial movement of the first and second catheter shafts. The number of turns and/or the length of the coiled endoprosthesis may be selectively changed using a single actuator and then released from the catheter.

A field programmable gate array has a plurality of programmable resources addressable per respective x and y dimensions of an x,y two dimensional array. A memory device provides a plurality of memory units that store configuration data for configuring associated programmable resources of the field programmable gate array. A controller addresses the memory device with an N-bit address for retrieving given configuration data. An address decoder and sequencer divides the N-bit address into first, second, and third portions and employs the first and third portions interchangeably, in accordance with the second portion, for addressing respective x and y dimensions of the plurality of programmable resources for selecting an associated programmable resource to be configured in accordance with the retrieved configuration data.

A study at the University of Nebraska Medical Center (UNMC) found that a novel device can significantly reduce contamination of blood cultures , potentially reducing risky overtreatment

0041]It should be noted that although a particular example of forming the heating and measuring devices is discussed above, any fabrication process which produces a pair of semiconductor devices such as FETs in thermal communication with one another may be suitable for the temperature measurement. As such, the temperature measurement method can work with any pair of devices where one of the devices produces heat, and the other device responds to that heat in some measurable way, such as one of its electrical characteristics changing in accordance with its temperature. It should also be noted that while the examples discussed above use two devices of similar design for heating and measuring, the measurement device and the heating device may be of completely different designs as long as the heating device is capable of heating and the measurement device is capable of measuring temperature and the two are in thermal contact. Additionally, two devices may be in thermal contact with one another ...

A biopsy cannula and a delivery catheter are configured to deliver one or more absorbable sponge pledgets to a biopsy site after removal of one or more tissue samples from the site. The delivery catheter allows a large amount of hydrated sponge material to be delivery to the biopsy site to facilitate hemostasis. One example of the delivery catheter includes a closed distal end, a side port, a tapered section, and an enlarged proximal portion for receiving the pledget. The side port of the delivery catheter is arranged to delivery the pledget through the side port of the biopsy cannula. In order to fill a relatively large biopsy site where multiple tissue samples have been taken in a radial pattern, the biopsy cannula is rotated and additional pledgets are delivered to the biopsy site at different radial locations. The absorbable sponge pledget may also be used as a marker for location of the biopsy site at a later time.

An embolic protection system comprises an embolic protection filter 1 having a collapsed delivery configuration and an expanded deployed configuration. The filter 1 is housed in the collapsed configuration in a reception space of a delivery catheter 20. The delivery catheter 20 containing the filter 1 is housed in a sealed sterile pouch 35. The filter 1 may be coated with a non-thrombogenic coating and an adhesion preventer 9 such as a silicon gel is used to substantially prevent adhesion of adjacent folds of the filter 1 when the filter is in the collapsed configuration in the delivery catheter 20.

The ability to have accurate and catheter based intravascular imaging provides interventional physicians with invaluable insight into the procedural vascular anatomy [1]. Luminal angiography has long been the gold standard for visualizing the arterial lumen and is routinely used for arterial reconstruction. Nevertheless, the structural composition of diseased arterial beds is not adequately visualized by angiography [2]. Intravascular imaging provides important structural information, which is frequently used for diagnostic and therapeutic decision making during the interventional procedure. The highest resolution source for intravascular imaging, optical coherence tomography (OCT), is a sub-surface imaging modality using near-infrared light [3].. Physicians use OCT to evaluate, characterize and understand intravascular anatomic features of normal and abnormal vessels. OCT accomplishes this via emission of a light source and no additional ioninizig radiation.. Initially, intravascular ultrasound ...

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Computed tomography (CT) is image reconstruction of objects using computer processed transmission or reflection data, usually referred to as projection data, from x-ray scanning. This projection data is often modeled using line integrals, but x-rays are of finite width in reality, so the accuracy of the projection data can be improved if an area based approach is used instead. In addition emitter beam shapes affect the reconstruction effectiveness and data collection efficiency, with the two main types of beam choice for 2-D scanning being fan beam and parallel beam. Fan beam scanning offers some advantages over parallel beam, such as faster data collection. This paper presents an area based fan beam projection model for CT and discusses its effectiveness based on numerical image reconstruction experiments using the proposed model, and several different reconstruction algorithms.

Embedded control of process plants is the state-of-the art development gaining importance by research community. Field Programmable Gate Array (FPGA) is a versatile tool for implementing embedded controller. In this paper the process of interfacing the Shell and Tube Heat Exchanger (STHE) with Compact Reconfigurable Input Output (CRIO) based FPGA through VDPID03DAQ card has been presented. The STHE VTPA-H-353 is a versatile and reliable computer based temperature process having microcontroller based data acquisition hardware unit. The DAQ card used for data acquisition consists of analog to digital converter, digital to analog converter and a microcontroller on a single board. A graphical program has been developed for the real time data acquisition using CRIO based FPGA. CRIO-9012 was interfaced with RS232 to the data acquisition card of STHE process plant. FPGA acts as a standalone processor instead of the PC for controlling the process plant.. ...

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In order to apply the terminal sliding mode control to robot manipulators, prior knowledge of the exact upper bound of parameter uncertainties, and external disturbances is necessary. However, this bound will not be easily determined because of the complexity and unpredictability of the structure of uncertainties in the dynamics of the robot. To resolve this problem in robot control, we propose a new robust adaptive terminal sliding mode control for tracking problems in robotic manipulators. By applying this adaptive controller, prior knowledge is not required because the controller is able to estimate the upper bound of uncertainties and disturbances. Also, the proposed controller can eliminate the chattering effect without losing the robustness property. The stability of the control algorithm can be easily verified by using Lyapunov theory. The proposed controller is tested in simulation on a two-degree-of-freedom robot to prove its effectiveness.. ...

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The plunger systems for use in an injector-actuated syringe of the present invention include a dynamic wedge seal which improves the sealing engagement between the plunger cover and syringe barrel, and flexible capture members extending from the rear surface of the plunger which permit the engagement and disengagement of the plunger from the injector drive means at any plunger position within the syringe. Further, the plunger systems include a contrast saving tip which expells the injection liquid from the syringe tip.

© Semiconductor Components Industries, LLC, 2006August, 2006 − Rev. 31Publication Order Number:NCP1522/DNCP15223.0 MHz, 600 mA,High−Efficiency, LowQuiescent Current,Adjustable Output Voltage datasheet search, datasheets, Datasheet search site for Electronic Components and Semiconductors, integrated circuits, diodes and other semiconductors.

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In the last two decades, capacitive micromachined ultrasonic transducers (CMUTs) have proven themselves to be promising for various ultrasound imaging and chemical sensing applications. Although holding many benefits for ultrasound imaging, CMUTs have certain weaknesses such as the relatively low output pressure at transmission, which hinder their development in the diagnostic imaging application. In the sensing area, CMUTs have shown attractive features such as high mass sensitivity, miniaturized array configuration, and ease of functionalization. However, their potential for humidity sensing is less explored. The objectives of this thesis lie in two aspects. One is to offer a solution to overcome the limitation of low output pressure, and the other is to develop CMUTs as resonant gravimetric humidity sensors. The major efforts are made on the second task. For the first objective, a novel dual-element ultrasonic transducer is proposed. It incorporates two transducer technologies by using a ...

TY - JOUR. T1 - Short-term in vivo studies of surface thrombosis in a left ventricular assist system. AU - Yamanaka, Hanako. AU - Rosenberg, Gerson. AU - Weiss, William. AU - Snyder, Alan J.. AU - Zapanta, Conrad M.. AU - Siedlecki, Christopher. PY - 2006/5/1. Y1 - 2006/5/1. N2 - Thrombosis continues to be a major adverse and at times fatal event in patients with left ventricular assist systems (LVAS). To assess acute thrombosis in an LVAS, multiscale analysis of surface thrombosis was performed on LVAS blood sacs retrieved after implantation in seven calves for 3 days. Two study groups were evaluated: One group was given heparin and warfarin sodium throughout the study; the second received no postoperative anticoagulation. On explantation, the blood sacs were examined for macroscopic thrombi; microscale thrombosis was assessed with the use of scanning electron microscopy. Macroscopic thrombi about 1 mm in diameter were seen in all sacs from both groups. Although macroscopic thrombi occurred in ...

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These industry measurement tools provide assessment of the strengths, threats, weaknesses and the present opportunities. It also elaborates the comprehensive industrial insights about the global Pressure Measurement Device market. Besides this, the research report examines the ongoing political scenarios that are anticipated to illustrate the pricing, import/ export in the worldwide Pressure Measurement Device market. Furthermore, the study report also explains the significant opportunities available in the overall global Pressure Measurement Device industry.. The research document on the global Pressure Measurement Device market includes a deep segmentation of the respective industry. The world Pressure Measurement Device market is segregated on the basis of application, major players, regions and product types. Each segment contains an in-depth explanation of the parameters that are likely to enhance and hamper the global Pressure Measurement Device market.. Major Industry Players Involved in ...

TY - GEN. T1 - Ultrahigh-speed ultrahigh-resolution adaptive optics. T2 - Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVII. AU - Jian, Yifan. AU - Xu, Jing. AU - Zawadzki, Robert. AU - Sarunic, Marinko V.. PY - 2013/5/22. Y1 - 2013/5/22. N2 - Small animal models of human retinal diseases are a critical component of vision research. In this report, we present an ultrahigh-resolution ultrahigh-speed adaptive optics optical coherence tomography (AO-OCT) system for small animal retinal imaging (mouse, fish, etc.). We adapted our imaging system to different types of small animals in accordance with the optical properties of their eyes. Results of AO-OCT images of small animal retinas acquired with AO correction are presented. Cellular structures including nerve fiber bundles, capillary networks and detailed double-cone photoreceptors are visualized.. AB - Small animal models of human retinal diseases are a critical component of vision research. In this report, we ...

TY - JOUR. T1 - Laparoscopic ultrasound manipulator with a spring-based elastic mechanism. AU - Arata, Jumpei. AU - Fukami, Kazunari. AU - Oguri, Susumu. AU - Onogi, Shinya. AU - Ikeda, Tetsuo. AU - Nakadate, Ryu. AU - Sakaguchi, Masamichi. AU - Akahoshi, Tomohiko. AU - Harada, Kanako. AU - Mitsuishi, Mamoru. AU - Hashizume, Makoto. PY - 2018/7/1. Y1 - 2018/7/1. N2 - Purpose: Image guidance is a key technology that can improve the outcome of laparoscopic surgery. However, due to the large deformation caused by digestive organs, a computer-aided navigation system based on preoperative imaging data cannot indicate the correct target position of the lesion (e.g., liver tumors and vessels invisible from the organ surface). To overcome this issue, we developed a laparoscopic ultrasound manipulator with two motorized degrees of freedom at the tip, allowing for the performance of a dexterous ultrasound scan in a confined laparoscopic surgical area. Method: The developed manipulator consists of a ...

Scanning laser ophthalmoscopy (SLO) and optical coherence tomography (OCT) are widely used retinal imaging modalities that can assist in the diagnosis of retinal pathologies. The combination of SLO and OCT provides a more comprehensive imaging system and a method to register OCT images to produce motion corrected retinal volumes. While high quality, bench-top SLO-OCT systems have been discussed in the literature and are available commercially, there are currently no handheld designs. We describe the first design and fabrication of a handheld SLO/spectral domain OCT probe. SLO and OCT images were acquired simultaneously with a combined power under the ANSI limit. High signal-to-noise ratio SLO and OCT images were acquired simultaneously from a normal subject with visible motion artifacts. Fully automated motion estimation methods were performed in post-processing to correct for the inter- and intra-frame motion in SLO images and their concurrently acquired OCT volumes. The resulting set of ...

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An embolic protection system 1 comprises a guidewire 99 for advancing through a vasculature, the guidewire 99 having a distal end and a proximal end; an embolic protection filter 1 having a filter body 41 with a distal end and a proximal end, the filter body 41 providing for a collapsed configuration and an expanded deployed configuration. The embolic protection filter body 41 has a guidewire path for slidably receiving the guidewire 99 to permit movement of the filter 1 relative to the guidewire 99 when the filter 1 is in the collapsed configuration and the expanded deployed configuration. A delivery catheter 2 is advanceable over the guidewire 99 for delivery of the embolic protection filter 1; the delivery catheter 2 having a proximal end and a distal end. The filter 1 is deployed from the distal end of the delivery catheter 2 into the expanded deployed configuration. A retrieval catheter 3 is also advancable over the guidewire 99 for retrieval of the filter 1, the retrieval catheter 3 having a

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Optical Coherence Tomography (OCT) shows great promise for low intrusive biomedical imaging applications. A parallel OCT system is a novel technique that replaces mechanical transverse scanning with electronic scanning. This will reduce the time required to acquire image data. In this system an array of small diameter fibers is required to obtain an image in the transverse direction. Each fiber in the array is configured in an interferometer and is used to image one pixel in the transverse direction. In this paper we describe a technique to package 15&mgr;m diameter fibers on a siliconsilica substrate to be used in a 2mm endoscopic probe tip. Single mode fibers are etched to reduce the cladding diameter from 125&mgr;m to 15&mgr;m. Etched fibers are placed into a 4mm by 150&mgr;m trench in a silicon-silica substrate and secured with UV glue. Active alignment was used to simplify the lay out of the fibers and minimize unwanted horizontal displacement of the fibers. A 10-channel fiber array was ...

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We describe a long-range optical coherence tomography system for size and shape measurement of large hollow organs in the human body. The system employs a frequency-domain optical delay line of a configuration that enables the combination of high-speed operation with long scan range. We compare the achievable maximum delay of several delay line configurations, and identify the configurations with the greatest delay range. We demonstrate the use of one such long-range delay line in a catheter-based optical coherence tomography system and present profiles of the human upper airway and esophagus in vivo with a radial scan range of 26 millimeters. Such quantitative upper airway profiling should prove valuable in investigating the pathophysiology of airway collapse during sleep (obstructive sleep apnea).. ©2003 Optical Society of America. Full Article , PDF Article ...

The overall goal of this thesis was to develop a dry powder delivery system for patients on mechanical ventilation. The studies were divided into two parts: the formulation development and the device design. The pulmonary system is an attractive route for drug delivery since the lungs have a large accessible surface area for treatment or drug absorption. For ventilated patients, inhaled drugs have to successfully navigate ventilator tubing and an endotracheal tube. Agglomerates of drug nanoparticles (also known as `NanoClusters) are fine dry powder aerosols that were hypothesized to enable drug delivery through ventilator circuits. This Thesis systematically investigated formulations of NanoClusters and their aerosol performance in a conventional inhaler and a device designed for use during mechanical ventilation. These engineered powders of budesonide (NC-Bud) were delivered via a Monodose® inhaler or a novel device through commercial endotracheal tubes, and analyzed by cascade impaction. ...

Simple devices use the concept of rectangular or quadrilateral area (l*b*0.785) calculation measured with the help of conventional rulers or scales. Another way to measure wound is by using a transparency sheet to outline the area which can be later measured in an area grid map. Complex devices are expensive and are more accurate in comparison to simple devices. Complex devices include optical instruments such as stereophotogrammeter (SPG) or structured lighting to obtain wound images which can be later on rendered by a computer to make a 3D image for further study and monitoring of the wound care. Wound measurement devices are yet in the developing stages with new innovations arising every year. However, common conclusion is that novel complex technologies are better in monitoring progress and examining the wound coverage area. Wound care has seen a great quantum of development in the present ages with the assistance from wound measurement devices. Hand held computers and smart phones are now ...

RTP Company can support your medical device development needs from virtually every angle. Not only do we provide standard products that are pre-tested to ISO 10993 biocompatibility standards, but we also offer custom and highly functionalized TPEs that are formulated to dissipate static electricity, provide radiopacity, and/or lower sliding friction force.. At RTP Company, we have structured our TPE product line to give the medical device design engineer ultimate flexibility. Our line of standard products provides time-tested performance in an array of devices, while our experienced R&D group is able to custom formulate unique TPE alloys and incorporate functional additives in support of your most demanding product developments.. For more information, view our innovation bulletin on Thermoplastic Elastomers for Medical Devices…. View Innovation Bulletin View alternative languages of this brochure: ...

Whether you need exact original equipment specification parts or high-quality replacement parts, you can rely on ACDelco Emission components, Fuel Injection and Control Modules to deliver. With our OE Service and Professional lines, we can keep your GM car, truck or SUV running in tip-top form. Our portfolio includes: Fuel Injectors, Control Modules, Mass Air Flow Sensors, Oxygen Sensors, Exhaust Gas Recirculation Valves, Manifold Absolute Pressure Sensors, Throttle Position Sensors, Idle Air Control Valves and Secondary Air Injection Reaction Systems. This solenoid is designed and manufactured to resolve an issue with the the Original Equipment (OE) canister solenoid. For your protection, this high quality canister solenoid valve kit is supplied with a 12-month/12,000-Mile Limited Warranty. AC Delco is a parts and service division of General Motors. The company has been in the automotive industry for over 100 years and it currently headquartered in Grand Blanc, Michigan. AC Delco is named for ...

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TY - JOUR. T1 - Equipment for essential surgical care in 9 countries across Africa. T2 - availability, barriers and need for novel design. AU - Oosting, Roos. AU - Wauben, Linda. AU - Groen, R.S.. AU - Dankelman, Jenny. PY - 2018. Y1 - 2018. N2 - Shortages of medical equipment in low-and-middle income countries (LMICs) have been found by several previous studies that assessed surgical capacity. To increase surgical capacity, there is a need to identify the availability of specific types of surgical equipment on a local, regional and national level. A survey was conducted among surgeons attending the annual meeting of the College Of Surgeons of East, Central and Southern Africa (COSECSA) in December 2016. General information of the facilities, availability of surgical equipment, reasons for limited availability, daily usage of equipment and equipment that could benefit from redesign were assessed. Forty-two respondents participated in this study, representing 33 individual healthcare facilities ...

TY - JOUR. T1 - A new implementation for online calculation of manipulator Jacobian. AU - Chembrammel, Pramod. AU - Kesavadas, Thenkurussi. PY - 2019/2. Y1 - 2019/2. N2 - This paper describes a new implementation for calculating Jacobian and its time derivative for robot manipulators in real-time. The estimation of Jacobian is the key in the real-time implementation of kinematics and dynamics of complex planar or spatial robots with fixed as well as floating axes in which the Jacobian form changes with the structure. The proposed method is suitable for such implementations. The new method is based on matrix differential calculus. Unlike the conventional methods, which are based on screw theory, the Jacobian calculation in the proposed approach has been reduced to the inner product of two matrices. Use of the new method to derive linear and angular velocity parts of Jacobian and its time derivative is described in detail. We have demonstrated the method using a two-DOF spatial robot and a ...

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The demonstration shows the performance of the temperature dependent Lithium-Ion battery model (Battery A) when the ambient temperature is varied from 20 degrees C to -20 degrees C and then to 0 degrees C. Battery B represents the case where the effect of temperature is neglected. Start the Simulation and open the Scope to view all signals.. At t = 0 s, the Battery A and B are discharged with 2 A at ambient temperature of 20 degrees C.. At t = 150 s, the internal temperature has increased to its steady state value of 29.2 degrees due to heat losses from the discharge process. This causes the output voltage of Battery A to slightly increase, while battery B output voltage continues to decrease.. At t = 1000 s, the ambient temperature is decreased to -20 degrees C. This causes the output voltage of Battery A to greatly decrease as the internal temperature decreases rapidly. Also the SOC of Battery A decreases due to the reduction of battery capacity. The battery B output voltage continues to ...

PA Consulting Groups medical device development team exhibited at the RDD Europe 2011 event in Berlin, Germany, 3 to 6 May 2001 with a focus on The future of drug delivery product development: closing the loop between treatment and patient response. Sarah Wren, and other PA experts in healthcare technology, were on hand throughout the event to discuss strategy scenarios for those dealing with drug-device combination product development, including such issues as:. ...

The present embodiments relate generally to patient monitoring system and, more particularly, to optical patient monitoring systems. In an embodiment, a physiological sensor includes a broadband emitter configured to emit two or more wavelengths of light into the tissue of a patient. The sensor also includes a charge coupled device (CCD) or complementary metal-oxide semiconductor (CMOS) photodetector array comprising a plurality of photodetectors. Each photodetector in the photodetector array is configured to receive the light from the tissue of the patient and to produce a corresponding output signal. Additionally, the sensor also includes one or more filter layers disposed on the plurality of photodetectors. The filter layers are configured to only allow light of particular wavelengths, polarizations, or both, to be received by each of the plurality of photodetectors.

Systems for connecting telecommunications infrastructure lines to telephones, handsets, computers, telecopy machines and other end user interfaces or consumer electronics devices in a residence or business. Systems according to the present invention include Network Control Units which form the center of a star topology and which communicate via RF link with Wireless Access Units and handsets. Wireless Access Units feature an interface, such as, for example, a standard telephone jack, for accommodating a telephone, a fax machine, a compute modem or other device. Computers or other devices may also be accommodated by Wireless Access Units having other physical and virtual interfaces, including, for instance, serial ports or network interfaces. The Wireless Access Units may also be digital to accommodate ISDN or any other digital standard. Wireless control/monitoring accessories may also be employed to communicate with the Network Control Unit and provide additional functionality such as entrance

Optical Fiber Sensors, Temperature, humidity and water leakage management, environmental monitoring, asset managements, IoT, temperature sensors, oil & Gas

Electrically conducting polymers were discovered in the late 1970s. This finding generated a whole new research area named organic electronics, an area which has attracted great interest and tremendous achievements, in terms of devices and applications, have been reached by different research groups all over the world. Replacing inorganic materials by their organic counterparts in various kinds of electronic devices provides novel device functionalities as well as new opportunities in device manufacturing. One of the major advantages of utilizing organic materials in electronic devices is the high degree of freedom regarding fabrication methods. Since organic materials can be processed from solution various printing, coating and lamination techniques can be used to manufacture entire electronic systems on flexible carriers and substrates in a truly reel-to-reel fashion.. The main theme of this thesis relates to exploring novel device architectures to enable easy manufacturing of flexible ...

Purpose: : To develop an optical coherence microscope that is capable of visualizing and quantifying cellular structures in the cornea. Methods: : The system is based on a spectral domain optical coherence tomography (OCT) which, to achieve high axial resolution, uses a broadband (600 to 1000nm) light of a supercontinuum source (Leukos SM-20). The system was assembled in free space to avoid axial resolution degradation due to dispersion. To achieve high lateral resolution with such a large bandwidth, chromatic aberration was minimized by constructing the system mostly using mirrors (an off-axis parabolic mirror for collimation and two concave mirrors for beam expansion) with the exception of the objective lens which was apochromatic for near infrared (correction range: 480 nm to 1800 nm) and has NA of 0.26. The objective has a working distance of 30.5 mm which allows for non-invasive measurement. The axial resolution of the system was estimated by measuring the full width at half maximum of the ...

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Hong Kong, China, July 12, 2017 /ChinaNewswire.com/ - Microsemi Corporation (Nasdaq: MSCC), a leading provider of semiconductor solutions differentiated by power, security, reliability and performance, announced new additions to its imaging/video solution supporting the popular Mobile Industry Processor Interface (MIPI) camera serial interface (CSI-2). The enhancements, including a new field programmable gate array (FPGA) mezzanine card (FMC)-based daughter card and new intellectual property (IP) which support image sensors with MIPI CSI-2 interfaces, enable customers to use the companys power-efficient, highly secure IGLOO?2 FPGA and SmartFusion?2 system-on-chip (SoC) FPGA capabilities in CSI-2-based camera systems.. As a standard specification by the MIPI Alliance, MIPI CSI-2 defines an interface between a peripheral device such as an image sensor and a host processor such as a baseband or application processor. Microsemis imaging and video solution is comprised of an imaging/video IP suite ...

Lease. Request Sample Report @ https://www.researchmoz.com/enquiry.php?type=S&repid=2548686&source=atm Important Key questions answered in MPV ACC Digital Signal Processor market report:. What will the market growth rate, Overview, and Analysis by Type of MPV ACC Digital Signal Processor in 2024?. What are the key factors affecting market dynamics? What are the drivers, challenges, and business risks in MPV ACC Digital Signal Processor market?. What is Dynamics, This Overview Includes Analysis of Scope and price analysis of top Manufacturers Profiles?. Who Are Opportunities, Risk and Driving Force of MPV ACC Digital Signal Processor market? Knows Upstream Raw Materials Sourcing and Downstream Buyers.. Who are the key manufacturers in space? Business Overview by Type, Applications, Gross Margin, and Market Share. What are the opportunities and threats faced by manufacturers in the global market?. You can Buy This Report from Here @ ...

You may need to go one size larger than your normal EU shoe size especially if you prefer a roomy fit.. The length and width of the insole of this shoe is as below. Remember the shoe has good volume in the forefoot so the actual comfortable width of this shoe will be a few mm greater than this flat measurement. Fit is personal, but most people will prefer to have at least 4 or 5mm spare room in front of your largest toe(s):. Size 36/222mm length, 89mm width, Size 37/228mm length, 91mm width, Size 38/234mm length, 93mm width, Size 39/243mm length, 95mm width, Size 40/247mm length, 97mm width, Size 41/253mm length, 99mm width, Size 42/260mm length, 100mm width. Length and width measurements taken as follows:. ...

Flexibility effects on robot manipulator design and control are typically ignored which is justified when large, bulky robotic mechanisms are moved at slow speeds However, when increased speed and improved accuracy is desired in robot system performance it is necessary to consider flexible manipulators. This project simulates the motion of a single-link, flexible manipulator using the Equivalent Rigid Link System dynamic model and experimentally validates the computer simulation results Validation of the flexible manipulator dynamic model is necessary to ensure confidence of the model for use in future design and control applications of flexible manipulators ...

Cell nuclei experience and respond to a wide range of forces, both in vivo and in vitro. In order to characterize the nuclear response to physical stress, we developed a microfluidic chip and used it to apply mechanical stress to live cells and measure their nuclear deformability. The device design is optimi

An electronic power supply for use with a personal computer exhibits a construction including an external power section located exterior to a personal computer and including a direct current voltage source in combination with a battery source for providing a load adjusted direct current voltage. A first supervisory computer is connected to the direct current voltage source and the battery source for controlling the load adjusted direct current voltage. An internal power section is located interior to the personal computer and in electrical contact with the external power section. The internal power section comprises a plurality of voltage output devices for providing a plurality of direct current output voltages. A second supervisory computer is connected to the plurality of voltage output devices for controlling the plurality of direct current output voltages distributed to the personal computer. A signal communication link exists between the second supervisory computer and the first supervisory

The purpose of this FOA is to encourage investigators to pursue translational and clinical studies for recording and/or stimulating devices to treat nervous system disorders and better understand the human brain. The program will utilize a cooperative agreement mechanism to support the submission of an Investigational Device Exemption (IDE) for a Significant Risk (SR) study or obtain Institutional Review Board (IRB) approval for a Non-Significant Risk (NSR) study, and a subsequent small clinical trial (e.g., Early Feasibility Study). The small clinical trial should provide data to answer key questions about the function or final design of a device. This final device design may require most, if not all, of the non-clinical testing on the path to more advanced clinical trials and market approval. The clinical trial is expected to provide information that cannot be practically obtained through additional nonclinical assessments (e.g., bench top or animal studies) due to the novelty of the device or ...

Current research in prosthetic device design aims to mimic natural movements using a feedback system that connects to the patients own nerves to control the device. The first step in using neurons to control motion is to make and maintain contact between neurons and the feedback sensors. Therefore, the goal of this project was to determine if changes in electrode resistance could be detected when a neuron extended a neurite to contact a sensor. Dorsal root ganglia (DRG) were harvested from chick embryos and cultured on a collagen-coated carbon nanotube microelectrode array for two days. The DRG were seeded along one side of the array so the processes extended across the array, contacting about half of the electrodes. Electrode resistance was measured both prior to culture and after the two day culture period. Phase contrast images of the microelectrode array were taken after two days to visually determine which electrodes were in contact with one or more DRG neurite or tissue. Electrodes in contact

Droplet-based microfluidics plays an important role in biological and chemical sciences. Different operations such as transport, reagent reaction, particles sorting, and merging can be achieved within a confined droplet. Droplet manipulation can be achieved in both passive and active ways. The passive way focuses on the ingenious device design and arrangement, while the active way incorporates external forces including but not limiting to thermocapillary force, electroweting force, and magnetic force. Numerical procedures were implemented to study multiphase systems in microchannels. The combined governing equations were employed to calculate the physical fields, which are solved using a finite volume method on the uniform Cartesian grid. The interfacial tension force and the magnetic force are coupled in the Navier-Stokes equation. The interface between two immiscible phases was captured using a particle level-set method. The accuracy of the present numerical codes was validated before ...