TY - JOUR. T1 - Predictive factors for inaccurate diagnosis of swollen lymph nodes in endoscopic ultrasound-guided fine needle aspiration. AU - Fujii, Yuki. AU - Kanno, Yoshihide. AU - Koshita, Shinsuke. AU - Ogawa, Takahisa. AU - Kusunose, Hiroaki. AU - Masu, Kaori. AU - Sakai, Toshitaka. AU - Yonamine, Keisuke. AU - Kawakami, Yujiro. AU - Murabayashi, Toji. AU - Kozakai, Fumisato. AU - Noda, Yutaka. AU - Okada, Hiroyuki. AU - Ito, Kei. N1 - Publisher Copyright: © 2019 Korean Society of Gastrointestinal Endoscopy.. PY - 2019. Y1 - 2019. N2 - Background/Aims: This study aimed to identify the predictive factors for inaccurate endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) diagnosis of swollen lymph nodes without rapid on-site cytopathological evaluation. Methods: Eighty-three consecutive patients who underwent EUS-FNA for abdominal or mediastinal lymph nodes from January 2008 to June 2017 were included from a prospectively maintained EUS-FNA database and retrospectively reviewed. ...
The aspiration smear revealed low cellularity with a clean background devoid of mucin. A few small collections of cuboidal epithelial cells with uniform round nuclei and pale cytoplasm were observed (Fig. 2A). The nuclear membranes were smooth, the chromatin was finely granular, and the nucleoli were small. The nuclear-cytoplasmic ratio was low. In a liquid-based preparation, two different cell populations were identified. The first population was composed of loose cell clusters of cuboidal cells with small, round nuclei and undefined cell borders (Fig. 2B). Sheets of atypical cells with disorderly arranged nuclei, occasional nuclear overlapping and nuclear grooves comprised the second cell population (Fig 2C). The cell borders were relatively well defined. These atypical cells were regarded as low-grade adenocarcinoma cells during the initial cytological diagnosis, but they were identified as gastric epithelial cells with degenerating atypia during retrospective review. Epithelial sheets with ...
TY - JOUR. T1 - Ultrasound-guided fine needle aspiration versus core needle biopsy. T2 - comparison of post-biopsy hematoma rates and risk factors. AU - Chae, In Hye. AU - Kim, Eun Kyung. AU - Moon, Hee Jung. AU - Yoon, Jung Hyun. AU - Park, Vivian Y.. AU - Kwak, Jin Young. N1 - Publisher Copyright: © 2017, Springer Science+Business Media New York.. PY - 2017/7/1. Y1 - 2017/7/1. N2 - Purpose: To compare post-biopsy hematoma rates between ultrasound guided-fine needle aspiration and ultrasound guided-core needle biopsy, and to investigate risk factors for post-biopsy hematoma. Methods: A total of 5304 thyroid nodules which underwent ultrasound guided biopsy were included in this retrospective study. We compared clinical and US features between patients with and without post-biopsy hematoma. Associations between these features and post-biopsy hematoma were analyzed. Results: Post-biopsy hematoma rate was 0.8% (43/5121) for ultrasound guided-fine needle aspiration and 4.9% (9/183) for ultrasound ...
Endobronchial Ultrasound-guided Transbronchial Needle Aspiration for Lymph Node Staging in Patients With Non-small Cell Lung Cancer Pursuing Stereotactic Body Radiation Therapy (SBRT)
Fingerprint Dive into the research topics of Usefulness of endobronchial ultrasound-guided transbronchial needle aspiration in distinguishing sarcoidosis from recurrent cancer in patients with lymphadenopathy after surgery. Together they form a unique fingerprint. ...
Introduction counties with higher diabetes mortality rates (see table 5.1 and figure 5.3a) but there are two counties Makanan Bagi Penderita Polip Hidung. #contour meter battery. Blood Glucose Numbers For Gestational Diabetes receive unlimited student support from our expert tutors. GDM=gestational diabetes mellitus; Video: Paula Deen Talks About Paula Deen Riding Things Meme. (Gncel Pediatri 2007; 5: 1-10) Anahtar kelimeler: Tip 1 diabetes mellitus. CHROMIUM PICOLINATE DIABETES ] The REAL cause of Diabetes Chromium Picolinate Diabetes Taking the Metformin HCl medications isnt enough to help Type 2 Diabetes.. Alternatively swelling may be due to a non-serious condition such as a side effect Endoscopic Ultrasound-Guided Fine Needle Aspiration of the Pancreas Richard A. Strengthen your outer hips to avoid injuries and to keep you limber. AstraZeneca and Lilly Expand Immuno-Oncology Research Collaboration with Your blood sugar goals may be different from these ideal goals. Diabetes can also ...
MRI depicts a 3 cm submucosal lesion on the anterior wall of the rectum, located 8.5 cm from the anal verge. The lesion has circumscribed smooth margins with intermediate signal intensity on T1-weighted images (Figure 1), low signal on T2-weighted images (Figure 2a, 2b) and low signal intensity on Diffusion Weighted Imaging with high b-value (Figure 3). Intravenous Gadolinium post contrast study revealed no contrast uptake (Figure 5). An endoscopic ultrasound-guided fine needle aspiration biopsy was suggested (Figure 6). There was also a small nodular focus, deep on the recto-uterine pouch, of high sinal intensity on T1-weighted fat-saturated images (Figure 4 ...
The imaging findings suggested the diagnosis of Immunoglobulin G4-related disease (IgG4-RD), manifested by autoimmune pancreatitis (AIP) and sclerosing cholangitis (SC). This hypothesis was confirmed by the elevated serum IgG4 (660,0 mg/dL) and histologic examination after endoscopic ultrasound-guided fine needle biopsy of the pancreas. The patient was treated with oral corticosteroids and antidiabetics, with successful remission of the disease. Recurrence of IgG4-RD was observed 5 years later, with renal involvement and serum IgG4 elevation.. IgG4-RD is a multiorgan immune-mediated fibroinflammatory condition, encompassing AIP, SC, retroperitoneal fibrosis, salivary gland and orbital disease. Previously thought as independent diseases, these manifestations were shown to share several features, namely organ enlargement due to lymphoplasmacytic infiltration by IgG4-positive plasma cells, obliterative phlebitis and fibrosis [1].. Biopsy is the diagnostic gold standard, with additional criteria ...
ISSN: (Print)/ (Online) Tuberc Respir Dis 2013;74:74-78 CopyrightC2013. The Korean Academy of Tuberculosis and Respiratory Diseases. All rights
Accurate lymph node staging is essential for adequate prognostication and therapy planning in patients with non-small cell lung cancer (NSCLC). FDG-PET/CT is a sensitive tool for the detection of metastases, including non-palpable supraclavicular lymph node (SCLN) metastases. Histological proof of metastatic spread and mutation analysis is crucial for optimal staging and therapy. The aim of this study was to investigate the value of ultrasound-guided fine needle aspiration cytology (FNAC) and core biopsy (CB) of FDG active, non-palpable SCLNs in patients with suspicion for lung cancer. Twelve consecutive patients with suspected lung cancer and FDG-positive SCLN underwent FNAC (n = 11) and/or CB (n = 10) and were included and evaluated retrospectively in this study. Cytologic and/or histologic evaluation was performed to confirm initially suspected diagnosis (lung cancer), to confirm N3 stage, and to screen for driver mutations in lung adenocarcinoma. FNAC alone showed diagnostic success in 11/11 cases
Ultrasound Features of Superficial and Palpable Lesions is a clinical reference guide designed to provide comparative ultrasound images and abbreviated text for use during superficial and palpable lesion ultrasound-guided fine needle aspiration (FNA). It serves as a quick reference for normal anatomy and abnormalities of superficial body sites. The laminated guide measures 7.5 by 6 inches, small enough to fit on an ultrasound instruments platform, and will assist procuring clinicians with on-site interpretation of ultrasound images. Contents include basic ultrasound principles and terminology, ultrasound nodule characteristics, ultrasound image artifacts, thyroid gland, parathyroid gland, lymph nodes, salivary gland, soft tissue, and breast ...
The objective of this course is to introduce the practicing surgeon to office-based ultrasound examination of the thyroid and parathyroid glands and related pathology. The distinction between normal and malignant lymphadenopathy will be emphasized with a demonstration of the comprehensive examination of lymph node basins in cervical levels I-VI. The process of ultrasound-guided fine needle aspiration (FNA) of thyroid nodules and enlarged lymph nodes will be demonstrated in didactic lecture format. In addition, the hands-on skill sessions allow the surgeon to learn varied techniques of FNA of lesions in phantom models. Patient volunteers will participate in the skill sessions. Credentialing and coding issues will also be discussed. CME Credit: The American College of Surgeons designates this live activity for a maximum of 7 AMA PRA Category 1 CreditsTM. Physicians should claim the only credit commensurate with the extent of their participation in the activity.. ...
One case of intraductal carcinoma of the parotid gland in a 67-year-old male patient is here introduced. The patient, who had a one-year history of a parotid mass, had undergone ultrasound and MRI examination that disclosed a 13x4x3 mm well delimited nodular mass of the accessory lobe of his left parotid gland. Ultrasound-guided Fine Needle Aspiration (FNA) had been performed by the clinician. The obtained smears showed widespread cellular necrosis in which cellular clusters with moderate and focally severe atypias displayed papillary and cribriform architecture and were admixed with sheets of epithelial cells with less striking nuclear atypias, squamous, or apocrine metaplasia ...
Two patients were diagnosed with malignant tumor of the parotid gland. In the case of a 6-year-old boy with rhabdomyosarcoma (lat. rhabdomyosarcoma embryonale), ultrasound examination revealed a well-vascularized solid polycyclic lesion measuring 20x18x14 mm. After 2 weeks, MRI examination revealed a mass in the superficial and deep lobe of parotid gland measuring 53x45x41 mm, reaching parapharyngeal space, modelling the lumen of nasopharynx, and compressing internal jugular vein. The invasion of neighboring structures was not observed. In the case of an 8-year-old boy with mucoepidermoid carcinoma (lat. carcinoma mucoepidermale), ultrasound examination revealed an oval, heterogenous, hypoechogenic tumor measuring 17x13x14 mm. Ultrasound-guided fine needle aspiration (FNA) was performed, and the results were identical with subsequent histopathological examination. No further imaging studies were performed. In both cases, the patients were qualified for surgical treatment, and then referred for ...
Dr. Ahmadian practices thyroidology as well as general endocrinology. Her special focus is on the diagnosis and medical treatment of thyroid dysfunction, nodules, and thyroid cancer. She is one of few ECNU-certified endocrinologist in Washington state. ECNU is a professional certification for endocrinologists who perform diagnostic ultrasound and ultrasound-guided fine needle aspiration for thyroid and parathyroid disorders. She also treats all disorders of the endcrine system such as adrenal disorder, PCOS, pituitary disorder, lipid disorder, osteoporosis and diabetes. ...
Recently Columbia oncologists diagnosed a toddler with acute myelogenous leukemia, and thanks to The Sohn Foundation for Precision Medicine, the entire family underwent genetic testing. Three of his siblings were found to have a gene linked to thyroid cancer. Their father was the carrier. Dr. Kuo found a suspicious thyroid nodule in his neck and with ultrasound-guided fine needle aspiration biopsy diagnosed medullary thyroid cancer, a rare and aggressive form of this disease. She operated the following week. With our early intervention, she says, there is a very good chance that the father has been completely cured and will remain cancer-free ...
7 cm) T3 (invasion) T4 (nodules same lobe) T4 (extension) M1 (ipsilateral lung) T4 (pleural effusion) M1 (contralateral lung) M1 (distant sites) T1a T1b T2a T2b T3 T4 M1a M1b N0 stage N1 stage N2 stage N3 stage IA IA IB IIA (IB) IIB (IB) IIB IIB (IIIB) IIIA (IIIB) IIIA (IV) IV (IIIB) IV IV IIA IIA IIA (IIB) IIB IIIA (IIB) IIIA (IB) IIIA (IIIB) IIIA (IIIB) IIIA (IV) IV (IIIB) IV IV IIIA IIIA IIIA IIIA IIIA IIIA IIIA (IIIB) IIIB IIIB (IV) IV (IIIB) IV IV IIIB IIIB IIIB IIIB IIIB IIIB IIIB IIIB IIIB (IV) IV (IIIB) IV IV Shaded areas are changes in classification of early stage NSCLC. 42. Szlubowski A, Zieli ski M, Soja J, et al. A combined approach of endobronchial and endoscopic ultrasound-guided needle aspiration in the radiologically normal mediastinum in non-small-cell lung cancer staging -a prospective trial. Eur J Cardiothorac Surg 2010; 37: 1175-9. 43. Herth FJ, Eberhardt R, Krasnik M, et al. Endobronchial ultrasound-guided transbronchial needle aspiration of lymph nodes in the ...
Sanchez-Navarro, I, R J da Silva, L, Blanco-Kelly, F, Zurita, O, Sanchez-Bolivar, N, Villaverde, C et al.. Combining targeted panel-based resequencing and copy-number variation analysis for the diagnosis of inherited syndromic retinopathies and associated ciliopathies. Sci Rep. 2018;8 (1):5285. doi: 10.1038/s41598-018-23520-1. PubMed PMID:29588463 PubMed Central PMC5869593 ...
Ambreen, S., Naseem, A., Ahmed, J., Khan, A. S., Shah, S. W., Raja, S. K., Khan, A., & Ansari, J. K. (2018). ENDOBRONCHIAL ULTRASOUND-GUIDED TRANS-BRONCHIAL NEEDLE ASPIRATION FOR THE DIAGNOSIS OF GRANULOMATOUS VERSUS NON GRANULOMATOUS LUNG DISEASES. Pakistan Armed Forces Medical Journal, 68(5), 1205-09. Retrieved from https://pafmj.org/index.php/PAFMJ/article/view/ ...
Fingerprint Dive into the research topics of Multiphase evaluation of contrast-enhanced endoscopic ultrasonography in the diagnosis of pancreatic solid lesions. Together they form a unique fingerprint. ...
A 63-year-old man was admitted to our clinic with left hilar lymphadenopathy on his chest radiography. Fluorodeoxyglucose positron-emission tomography showed multiple regions of high metabolic activity on the left pleura and left interlobar lymph nodes. Histopathological examination of the lymph node material obtained by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) revealed malignant mesothelioma. This case report demonstrates the usefulness of EBUS-TBNA in the diagnosis of metastatic mesothelioma.. Keywords: endobronchial ultrasonography (EBUS), mediastinal lymph node, ...
Case Reports in Gastrointestinal Medicine is a peer-reviewed, Open Access journal that publishes case reports and case series focusing on gastroenterology, hepatology, pancreas and biliary, and related cancers.
TY - JOUR. T1 - Risk Factors of Infectious Complications After Endobronchial Ultrasound-Guided Transbronchial Biopsy. AU - Souma, Tomohide. AU - Minezawa, Tomoyuki. AU - Yatsuya, Hiroshi. AU - Okamura, Takuya. AU - Yamatsuta, Kumiko. AU - Morikawa, Sayako. AU - Horiguchi, Tomoya. AU - Maeda, Shingo. AU - Goto, Yasuhiro. AU - Hayashi, Masamichi. AU - Isogai, Sumito. AU - Yamamoto, Naoki. AU - Kondo, Masashi. AU - Imaizumi, Kazuyoshi. N1 - Publisher Copyright: © 2020 The Authors. PY - 2020/8. Y1 - 2020/8. N2 - Background: Infectious complications after endobronchial ultrasound-guided transbronchial biopsy with a guide sheath (EBUS-GS-TBB) are serious in that they may delay or change scheduled subsequent therapy. The aim of this study was to identify risk factors for infection after EBUS-GS-TBB. Research Question: What are the risk factors for infection after EBUS-GS-TBB? Study Design and Methods: We retrospectively reviewed the medical records of 1,045 consecutive patients who had undergone ...
Thyroid: Surgical diseases of the thyroid gland include benign nodules, thyroid cancers, and hyperfunctioning states such as Graves disease. Thyroid nodules are commonly discovered on physical exam or when a radiologic study of the neck is performed for other reasons. Most of these nodules are benign, but about 10% can contain thyroid cancer. The initial workup of these nodules is most often performed by primary care physicians, endocrinologists, or endocrine surgeons. The evaluation will include laboratory analysis, ultrasound, and often a fine needle biopsy. Both diagnostic ultrasound and ultrasound-guided fine needle aspiration biopsy of the thyroid are performed in the office, and can usually be accomplished at the time of first consultation. If the biopsy diagnoses or raises suspicion for thyroid cancer, a thyroidectomy is usually necessary. The ultrasound also allows for a thorough evaluation of lymph nodes that may be involved with thyroid disease.. Benign thyroid diseases such as ...
TY - JOUR. T1 - Application of Thyroid Imaging Reporting and Data System in the Ultrasound Assessment of Thyroid Nodules According to Physician Experience. AU - Ko, Su Yeon. AU - Kim, Eun Kyung. AU - Moon, Hee Jung. AU - Yoon, Jung Hyun. AU - Kim, Ha Yan. AU - Kwak, Jin Young. N1 - Publisher Copyright: © 2016 Wolters Kluwer Health, Inc. All rights reserved.. PY - 2016/6/1. Y1 - 2016/6/1. N2 - Objective The aim of this study was to investigate and compare the diagnostic performances of the Thyroid Imaging Reporting and Data System (TIRADS) in differentiating benign and malignant thyroid nodules according to the level of physician experience. Materials and Methods From March to October 2013, 1102 patients with 1128 thyroid nodules who underwent initial ultrasound-guided fine needle aspiration were included in this study. Thyroid nodules were categorized according to TIRADS. Diagnostic performances of ultrasound were compared according to performer experience using the χ2 test or Fisher exact ...
The evaluation of mediastinal lymph nodes is critical for the correct staging of patients with lung cancer (LC). Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive technique for mediastinal staging, though unfortunately lymph node micrometastasis is often missed by cytological analysis. The aim of this study was to evaluate the predictive capacity of methylation biomarkers and provide a classification rule for predicting malignancy in false negative EBUS-TBNA samples. The study included 112 patients with a new or suspected diagnosis of LC that were referred to EBUS-TBNA. Methylation of p16/INK4a, MGMT, SHOX2, E-cadherin, DLEC1, and RASSF1A was quantified by nested methylation-specific qPCR in 218 EBUS-TBNA lymph node samples. Cross-validated linear regression models were evaluated to predict malignancy. According to EBUS-TBNA and final diagnosis, 90 samples were true positives for malignancy, 110 were true negatives, and 18 were false negatives. MGMT,
TY - JOUR. T1 - Non-cardiac thoracic ultrasound in 75 feline and canine patients. AU - Reichle, Jean K.. AU - Wisner, Erik R. PY - 2000/3. Y1 - 2000/3. N2 - The purpose of this study was to describe the ultrasonographic appearance of non-cardiac diseases of the small animal thorax. Ultrasound images from a total of 75 animals (26 cats and 49 dogs) were compared to cytologic, histopathologic, and necropsy findings. Clinical diagnoses included neoplasia of the mediastinum, pleura, or lungs (43); idiopathic mediastinal cyst (3); diaphragmatic or peritoneo-pericardial hernia (4); lung lobe torsion (1); pulmonary eosinophilic infiltrates (1); and idiopathic, chylous, congestive heart failure, or lymphangiectasia associated pleural effusion (14). In the remaining 9 patients, a definitive diagnosis was not obtained. Ultrasound-guided fine needle aspirate was performed in 56 patients; 1 of these also had an ultrasound-guided tissue core biopsy. Of the fine needle aspirates, 51 (91%) were diagnostic. ...
OCC File number: 2011-7920 History:. The decedent was an 80-year-old male who was found to have an incidental, solitary pulmonary nodule in his right lung following routine radiographic imaging of his chest in April 2011 to assess a previously implanted endovascular stent within his thoracic aorta. This nodule was reported to be pleural based within the right upper lobe and approximately 1.4 cm in greatest dimension. An ultrasound-guided fine needle aspirate of this nodule in the anterior segment of the right upper lobe was obtained on April 26, 2011 and reported as Positive for Malignant Cells / Non-Small Cell Carcinoma. A whole body Positron Emission Tomography - Computed Tomography (PET-CT) scan was performed which demonstrated that the nodule was 15 mm x 13 mm and metabolically active. No evidence of metabolically active foci was identified within the intrathoracic lymph nodes or elsewhere to suggest metastatic disease. [Of note, in the body of this PET-CT report, the nodule is recorded as ...
An endoscopic ultrasound (EUS) is a test to look at the inside of your gastrointestinal (GI) tract. Its commonly used to look for cancers or growths in the esophagus, stomach, pancreas, liver, and rectum.
Endoscopic ultrasound (EUS) uses a specialized endoscope-a long, flexible, lighted tube-equipped with a small ultrasound probe, which emits sound waves.
Placement of an ultrasound-guided peripheral intravenous line (USPIV) is a common and relatively safe procedure. Dont fall into bad habits that lead to unsuccessful placement. Review the most common (and correctable) pitfalls.
Supplementary MaterialsSupplementary Information 41467_2020_16827_MOESM1_ESM. glioma stem cells (GSCs) as well as the tumor microenvironment has crucial roles to advertise malignant development of glioblastoma (GBM), one of the most lethal human brain tumor. However, the molecular mechanisms underlying this crosstalk are understood incompletely. Here, we display that GSCs secrete the Wnt\induced signaling proteins 1 (WISP1) to facilitate a pro-tumor microenvironment by advertising the success of both GSCs and tumor-associated macrophages (TAMs). WISP1 is expressed and secreted by GSCs preferentially. Silencing WISP1 disrupts GSC maintenance, decreases tumor-supportive TAMs (M2), and inhibits GBM development potently. WISP1 signs through Integrin 61-Akt to keep up GSCs by an autocrine M2 and system TAMs through a paracrine way. Significantly, inhibition of Wnt/-catenin-WISP1 signaling by carnosic acidity (CA) suppresses GBM tumor development. Collectively, these data demonstrate Mirk-IN-1 that ...
I still struggle a lot with OCD guilt. You know the kind Im talking about -- guilt over things that either no one else cares about, or that happened decades
TY - JOUR. T1 - Is pancreatitis a complication of endoscopic ultrasound guided fine needle aspiration of the pancreas?. AU - Gress, F.. AU - Ikenberry, S.. AU - Ciaccia, D.. AU - Kiel, J.. AU - Lehman, Glen. PY - 1997. Y1 - 1997. N2 - Introduction: Endoscopic ultrasound (EUS) guided fine needle aspiration (FNA) of the pancreas is increasingly being utilized to diagnose pancreatic masses. We have previously reported 2 cases of clinical pancreatitis following EUS guided FNA of the pancreas. Aim of Study: To determine the frequency of chemical and clinical pancreatitis following EUS guided FNA of the pancreas. Methods: All patients having EUS guided FNA biopsy of the pancreas were eligible. Exclusion criteria included: All patients with acute pancreatitis or having ERCP within 48 hours of the EUS FNA. Serum amylase and lipase levels were measured immediately prior to and 2 hours post EUS FNA. Patients were called 24-72 hours after FNA to follow up for increased pain, nausea, or vomiting suggesting ...
Looking for online definition of endoscopic ultrasound-guided fine-needle aspiration in the Medical Dictionary? endoscopic ultrasound-guided fine-needle aspiration explanation free. What is endoscopic ultrasound-guided fine-needle aspiration? Meaning of endoscopic ultrasound-guided fine-needle aspiration medical term. What does endoscopic ultrasound-guided fine-needle aspiration mean?
Convex probe endobronchial ultrasound is a minimally invasive technique used for performing real-time transbronchial needle aspiration of enlarged hilar and mediastinal lymph nodes and could be used for diagnosing proximal peribronchial lesions. Although computed tomography, magnetic resonant imaging, and positron emission tomography/computed tomography have relatively high sensitivity for mediastinal evaluation, pathology is the gold standard. This study compared between Echo Tip Ultra HD-EBUS 22G needle and Echo Tip ProCore HD-EBUS 22G needle in diagnosis of mediastinal lesions using convex probe endobronchial ultrasound. Twenty-four patients with mediastinal lesions were included. Convex probe endobronchial ultrasound-guided transbronchial needle aspiration using both Echo Tip Ultra HD 22G and Echo Tip ProCore HD 22G needles was done to all patients with no peripheral lymph node enlargement. CP-EBUS TBNA had diagnostic accuracy 50%, sensitivity 47.6%, and specificity 100% in diagnosis of mediastinal
TY - JOUR. T1 - Endobronchial ultrasound and lymphoproliferative disorders. T2 - A retrospective study. AU - Iqbal, Seher. AU - Depew, Zachary S.. AU - Kurtin, Paul J.. AU - Sykes, Anne Marie G.. AU - Johnson, Geoffrey B.. AU - Edell, Eric S.. AU - Habermann, Thomas M.. AU - Maldonado, Fabien. PY - 2012/12/1. Y1 - 2012/12/1. N2 - Background: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has been shown to have excellent diagnostic performance for mediastinal staging of lung cancer. The utility of EBUS-TBNA for the diagnosis of lymphoproliferative disorders involving the mediastinum or hila, or both, is unclear. Methods: A retrospective analysis was completed of all patients diagnosed with a lymphoproliferative disorder involving the mediastinum or hila, or both, who underwent an EBUS-TBNA within 3 months of the diagnosis. Results: Sixty-five patients with mediastinal or hilar lymph node, or both, involvement of their lymphoproliferative disorder underwent EBUS-TBNA ...
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive procedure. This procedure is useful for nodal staging of l...
TY - JOUR. T1 - A prospective study of conventional transbronchial needle aspiration. T2 - performance and cost utility.. AU - Medford, A. R.. AU - Agrawal, S.. AU - Free, C. M.. AU - Bennett, J. A.. PY - 2010. Y1 - 2010. N2 - BACKGROUND: Conventional transbronchial needle aspiration (TBNA) is a cheap, minimally invasive tool for lung cancer staging and diagnosis. Endobronchial ultrasound-guided TBNA (EBUS-TBNA) is more sensitive but is more expensive and less widely available. We describe a prospective analysis of TBNA diagnostic, staging and cost utility in a centre in the UK. Objectives: To illustrate the potential diagnostic, staging and cost utility of a low cost conventional TBNA service. METHODS: A prospective analysis of 79 TBNA procedures over a 2-year period was performed looking at performance and cost utility in a mixed cohort with variable pre-test probability of malignancy (year 1) followed by a high probability cohort (year 2). RESULTS: TBNA avoided mediastinoscopy in 25% of the ...
Purpose: Anaplastic lymphoma kinase (ALK) fusion genes represent novel oncogenes for non-small cell lung cancers (NSCLC). Several ALK inhibitors have been developed, and are now being evaluated in ALK-positive NSCLC. The feasibility of detecting ALK fusion genes in samples obtained by endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) was determined. The clinicopathologic characteristics of ALK-positive lung cancer were also analyzed.. Experimental Design: From April 2008 to July 2009, NSCLC cases with hilar/mediastinal lymph node metastases detected by EBUS-TBNA were enrolled. Positive expression of ALK fusion protein was determined using immunohistochemistry, and ALK gene rearrangements were further examined to verify the translocation between ALK and partner genes using fluorescent in situ hybridization and reverse transcription-PCR. Direct sequencing of PCR products was performed to identify ALK fusion variants.. Results: One hundred and nine cases were eligible for ...
Recommendation: The clinical presentation is consistent with a cold thyroid gland nodule. The possibility of malignancy is not excluded based on normal thyroid gland function. The workup of such thyroid gland nodules evolved over the past decade. Currently, an ultrasound-guided fine needle biopsy is recommended. The results of the cytology can guide the treatment: observation is recommended for a macrofollicular pattern or clear benign colloid pattern, while surgery is recommended for microfollicular pattern or clear evidence of carcinoma.. The extent of surgery is dictated by the histology as well: a hemithyroidectomy is reasonable if the needle biopsy was not diagnostic of carcinoma but showed a microfollicular pattern. In such a case, it is recommended to perform frozen section histopathology examination of the surgical specimen and proceed to total or subtotal thyroidectomy if cancer was found on the frozen section diagnosis. On the other hand, a total or subtotal thyroidectomy is ...
Endoscopic ultrasound-guided sampling of solid pancreatic masses: the fine needle aspiration or fine needle biopsy dilemma. Is the best needle yet to come?
Results The final diagnosis was adenocarcinoma in 156 patients (67%), neuroendocrine tumor in 27 (12%), lymphoma in 6 (3%), metastatic malignancy in 8 (4%), and benign etiologies in 35 (15%). CP was identified in 44/234 (19%) patients. The overall diagnostic sensitivity, specificity, positive predictive value, negative predictive value, and accuracy for EUS-FNA were 92.9%, 97.1%, 99.5%, 70.8%, and 93.5%, respectively. The sensitivity (80% vs. 95%, P=0.020) and accuracy (86% vs. 95%, P=0.043) were significantly lower in patients with CP compared to those without CP. ...
Boland MR, Prichard RS;Daskalova I;Lowery AJ;Evoy D;Geraghty J;Rothwell J;Quinn CM;ODoherty A;McDermott EW (2015) Axillary nodal burden in primary breast cancer patients with positive pre-operative ultrasound guided fine needle aspiration cytology: management in the era of ACOSOG Z011. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 41 (4):559-565. [DOI] [Details] ...
Of 8,936 endoscopic ultrasound examinations, 73 repeated procedures were identified, and 24 were excluded.. The 49 initial endoscopic ultrasound procedures were done in Indiana or another state, by one of 15 physicians in private practice, or at a teaching hospital.. The researchers performed an endoscopic ultrasound-guided fine-needle aspiration during an initial endoscopic ultrasound in 21 patients.. This method was not attempted in 14 patients.. The principle indication for a repeated endoscopic ultrasound in 35 patients was for an endoscopic ultrasound fine-needle aspiration after the initial tissue sampling was benign, nondiagnostic, or not done.. The researchers noted that a second endoscopic ultrasound had no clinical impact in 37% of patients.. The team found that in the remaining 63% of patients, a repeated endoscopic ultrasound provided a new or changed clinical diagnosis.. Dr DeWitts team commented, In this study, a repeated endoscopic ultrasound at a tertiary-referral center had a ...
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1. Prepare one alcohol-fixed slide and one air-dried slide for each pass of aspiration - see Non-Gynaecological smear, fluid and Fine Needle Aspiration (FNA) - General Instruction for details.. 2. Aspirate the remaining material into a sterile container. 3. Submit a maximum of 4 slides per lesion.. 4. The slides should be labelled wet-fixed or air-dried as appropriate. 5. If multiple sites or organs are aspirated, indicate exact sites/organs aspirated on the CPOE request as well as on the frosted end of slides.. 6. If fluid is aspirated, collect into a sterile container. Indicate the site from which fluid is collected and submit to the laboratory in one CPOE request. 7. Clinical information is required for the pathologist to render a diagnosis. Please indicate in the CPOE request the specific site, clinical diagnosis, whether the lesion is solid or cystic and gross appearance of the aspirate if applicable. A cytology non-gynaecological CPOE request that is completed and properly filled up - ...
At Optima Diagnostic Imaging, we provide CT and Ultrasound guided biopsies to help with early detection of conditions and diseases.
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Battling cancer is hard enough. At first, my husband and I were very concerned about where we were going to receive treatment in my fight for survival. After talking with the doctor at CBC, we knew that Read More ...
A endoscopic ultrasound allows physicians to see detailed imaging of the upper & lower digestic tract and surrounding organs. Call today!