List of causes of Emphysema-like symptoms and Exercise symptoms and Gerd-like chest pain and Severe heartburn after eating, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.
List of 42 causes for Gerd-like chest pain and Severe emphysema-like cough symptoms and Severe heartburn after eating, alternative diagnoses, rare causes, misdiagnoses, patient stories, and much more.
Diagnostic Tests for Chronic emphysema-like symptoms symptoms including blood tests, urine tests, swabs, diagnostic tests, lab tests, and pathology testing.
INTRODUCTION: Emphysematous gastritis (EG) is a rare condition characterized by air within the gastric wall with signs of systemic toxicity. The optimal management for this condition and the role of surgery is still unclear. We here report three cases of EG successfully managed non-operatively. PRESENTATION OF CASES: All three of our patients were elderly females with several co-morbidities. The chief presenting symptom was abdominal pain with signs of systemic toxicity ranging from tachycardia and hypotension to acute kidney injury. Computed tomography (CT) scan revealed gastric pneumatosis in all patients. One patient had extensive portal venous gas, and another had free intraperitoneal air. All patients were managed with nothing by mouth, proton pump inhibitors, intravenous fluid resuscitation, and antibiotics. Repeat CT scan in two patients in 3-4 days demonstrated resolution of the pneumatosis. They were all discharged home tolerating an oral diet. DISCUSSION: The presentation of EG is non-specific
In spite of the growing efforts oriented towards revealing different aspects of emphysema, the persistence of the emphysematous or emphysema-like changes (ELCs) is not explored yet in the open literature. In this study we demonstrate the persistence of an ELC for 22 years in a spontaneous pneumothorax (SP) patient which indicates a hitherto unknown gas supply to the ELC. For this purpose we used high resolution computed tomography (HRCT) images processed into three-dimensional (3D) geometry. By the same token, not only a long persistence but also the volume increase of this ELC between 2002 and 2010 was demonstrated. The 3D geometry visualized an aerated interstitial structure between the sites of supposed gas leakage at the wall of the third generation airways and the ELC. This potential gas conducting interstitial pathway is not a continuation and has neither the form nor the structure of a bronchus. The finding suggests that in this patient the intrabronchial gas passes through the bronchial ...
Primary spontaneous pneumothorax (PSP), or collapsed lung, results from the presence of air in the pleural space in the absence of a precipitating event such as trauma or lung disease. Affected individuals have subpleural blebs or bullae in the lungs (localized emphysema-like changes) that are associated with destruction of lung tissue. The majority of cases are sporadic. Isolated familial PSP is rarer, and has been associated with mutations in the FLCN gene in a small number of families ...
Emphysematous cystitis is a rare type of infection of the bladder wall by gas-forming bacteria or fungi. The most frequent offending organism is E. coli. Other gram negative bacteria, including Klebsiella and Proteus are also commonly isolated. Fungi, such as Candida, have also been reported as causative organisms. Citrobacter and Enterococci have also been found to cause Emphysematous cystitis (Mokabberi). Although it is a rare type of bladder infection, it is the most common type of all gas-forming bladder infections (Mccabe). The condition is characterized by the formation of air bubbles in and around the bladder wall. The gas found in the bladder consists of nitrogen, hydrogen, oxygen, and carbon dioxide. The disease most commonly affects elderly diabetic and immunocompromised patients (Sereno). The first case was identified in a post-mortem examination in 1888 (Nemati, Basra). Signs and symptoms of emphysematous cystitis include air in the bladder wall, altered mental status, severe ...
Introduction: Emphysematous pyelonephritis (EPN) is a severe, life-threatening infection of the renal parenchyma. This condition is characterized by the production of intrarenal and perinephric gas. In the world, the EPN is currently limited to case series reported. No cases have been described in black Africa. Aims: Related a first case of EPN diagnosed and treated in the University Hospital Center Sylvanus Olympio of Lomé in Togo. Observation: A 40 years old woman, with antecedent of diabetes presented pyelonephritis emphysematous class 2. She was treated successfully with antibiotic alone without using percutaneous drainage or nephrectomy. Conclusion: As reported in every case series, it was a young diabetic patient with a clinical features of acute pyelonephritis which CT scan had helped lay the EPN class 2 diagnosed. The germ was Klebsiella pneumoniae. She was treated with adapted antibiotic alone.
Emphysematous pyelonephritis (EPN) is a rare condition which can rapidly progress to sepsis and multiple organ failure with high mortality. We experienced a rare case of EPN in a renal allograft related to antibody-mediated rejection (AMR). The patient received a deceased donor kidney transplant due to end-stage renal disease secondary to diabetes mellitus. Cross-match test was negative but she had remote history of anti-HLA-A2 antibody corresponding with the donor HLA. Surgery concluded without any major events. Anti-thymoglobulin was given perioperatively for induction. She was compliant with her immunosuppressive medications making urine of 2 L/d with serum creatinine of 1.9 mg/dL at discharge on post-operative day (POD) 6. She did well until POD 14 when she presented to the clinic with features of sepsis, pain over the transplanted kidney area and decline in urine volume with elevated serum creatinine. CT revealed extensive gas throughout the transplanted kidney. Renal scan revealed non-functional
Imaging is essential to managing emphysematous pyelonephritis -a life-threatening, fulminant, necrotizing upper urinary tract infection associated with gas within the kidney-if an early diagnosis is to be made and a potentially devastating outcome is to be avoided. Some confusion exists regarding terminology for conditions involving renal gas.
Evaluation of cigarette smoke-induced emphysema in mice using quantitative micro-computed tomography(審査報告)Evaluation of cigarette smoke-induced emphysema in mice using quantitative micro-computed tomography(審査報告) ...
National Trial Yields First Scientific Evidence of Who Should Have Surgery-. New York, NY (Aug. 14, 2001) - The National Emphysema Treatment Trial (NETT), in which Columbia Presbyterian Medical Center of NewYork-Presbyterian Hospital is a major participant, has found that certain advanced emphysema patients benefit little from Lung Volume Reduction Surgery (LVRS) and are at unacceptable risk of death from the procedure. The NETT trial - a five-year, multicenter, randomized study designed to evaluate the role of LVRS in the treatment of severe emphysema - indicates that those patients who have severe lung obstruction with either limited ability to exchange gas while breathing or damage that is evenly distributed throughout their lungs should not undergo LVRS ...
TY - JOUR. T1 - Evaluation of cigarette smoke-induced emphysema in mice using quantitative micro-computed tomography. AU - Sasaki, Mamoru. AU - Chubachi, Shotaro. AU - Kameyama, Naofumi. AU - Sato, Minako. AU - Haraguchi, Mizuha. AU - Miyazaki, Masaki. AU - Takahashi, Saeko. AU - Betsuyaku, Tomoko. PY - 2015/5/15. Y1 - 2015/5/15. N2 - Chronic cigarette smoke (CS) exposure provokes variable changes in the lungs, and emphysema is an important feature of chronic obstructive pulmonary disease. The usefulness of micro-computed tomography (CT) to assess emphysema in different mouse models has been investigated, but few studies evaluated the dynamic structural changes in a CS-induced emphysema mouse model. A novel micro-CT technique with respiratory and cardiac gating has resulted in high-quality images that enable processing for further quantitative and qualitative analyses. Adult female C57BL/6J mice were repeatedly exposed to mainstream CS, and micro-CT scans were performed at 0, 4, 12, and 20 wk. ...
TY - JOUR. T1 - A rare cause of acute lower abdominal pain: Emphysematous cystitis.. AU - Ergun, Tarkan. AU - Eldem, Halil Olcay. AU - Lakadamyali, Hatice. PY - 2014. Y1 - 2014. M3 - Article. VL - 40. SP - 65,67. JO - Turk J Urol.. JF - Turk J Urol.. IS - 1. ER - ...
This study has shown that the severity of emphysema varies widely despite the same disease stage in COPD. For instance, even in patients with moderate or severe COPD, some show very little evidence of emphysema while others have marked emphysema. Furthermore, some patients retain relatively normal pulmonary function despite the presence of severe emphysema. These observations support the findings of several past studies which argued against emphysema as the major cause of airflow limitation in COPD.1 21-23. All subjects were then classified into three groups based on the severity of emphysema. Although the small airways were not directly evaluated in this study, the extremely wide variation in severity of emphysema observed among subjects with the same degree of airflow limitation appeared to indicate that the three groups might well represent differences in relative contributions of small airway disease and emphysema to airflow limitation. The most important findings in this study were that ...
The goal of this study was to identify gene expression changes associated with regional emphysema severity in order to elucidate biological processes underlying the progression of emphysema and to identify potential COPD therapeutics. By measuring gene expression from regions of varying emphysema severity within the same lung and by using a morphologic measurement of airspace size (Lm), which reflects the degree of alveolar destruction, we were able to identify gene expression changes associated specifically with the emphysematous component of COPD.. Interestingly, there was significant enrichment between genes differentially expressed in COPD or associated with worsening lung function in other datasets and those we found to be associated with regional emphysema severity. Importantly, this similarity supports the notion that regional differences in emphysema severity reflect the processes that occur with general COPD pathogenesis and progression and are not only present in patients with ...
Emphysema is largely an under-diagnosed medical condition that can exist in smokers in the absence of airway obstruction. We aimed to determine the sensitivity and specificity of pulmonary function tests (PFTs) in assessing emphysema using quantitative CT scans as the reference standard. We enrolled 224 ever-smokers (current or former) over the age of 40. CT of thorax was used to quantify the low attenuation area (% emphysema), and to measure the standardized airway wall thickness. PFTs were used individually and in combination to predict their ability to discriminate radiographic emphysema. Significant emphysema (|7%) was detected in 122 (54%) subjects. Twenty six (21%) emphysema subjects had no evidence of airflow obstruction (FEV1/FVC ratio 23% emphysema showed airflow obstruction. The sensitivity and specificity of spirometry for detecting radiographic emphysema were 79% and 75%, respectively. Standardized airway wall thickness was increased in subjects with airflow obstruction, but did not
Hippocrates may well have appreciated the significance of the presence of emphysema, but it was not until the 17th century that Bonet1 described the larger lungs of those with emphysema, to which he attributed their breathlessness. In 1821, Laennec connected emphysema to ageing, when he ascribed a subtly different definition to emphysema, describing it as "a breakdown of tissue in the parenchyma of the lungs as opposed to air trapped in the alveoli due to obstruction as occurs in asthma and chronic bronchitis" essentially considering emphysema to be an independent finding to obstructive lung disease, although at postmortem.2 Fast forward 200 years, and one could argue that even in 2016 the significance of emphysema on a CT scan in someone who does not have airflow obstruction or clinical symptoms of breathlessness is unclear.. Even the significance of emphysema among people with COPD and the association between emphysema and smoking are obscure. Around half of patients with COPD do not have ...
Chronic obstructive pulmonary disease (COPD) is an incurable and progressive disease. Emphysema is the principal manifestation of COPD, and the main cause of this condition is cigarette smoke (CS). Natural products have shown antioxidant and anti-inflammatory properties that can prevent acute lung inflammation and emphysema, but there are few reports in the literature regarding therapeutic approaches to emphysema. We hypothesized that supplementation with natural extracts would repair lung damage in emphysema caused by CS exposure. Mice were exposed to 60days of CS and then treated or not with three different natural extracts (mate tea, grape and propolis) orally for additional 60days. Histological analysis revealed significant improvements in lung histoarchitecture, with recovery of alveolar spaces in all groups treated with natural extracts. Propolis was also able to recovery alveolar septa and elastic fibers. Propolis also increased MMP-2 and decreased MMP-12 expression, favoring the process of
CASE SUMMARY A 74-year-old obese woman with a long-standing history of uncontrolled type II diabetes mellitus was admitted to the hospital for an acute asth...
Renal Infection is an infection of kidney which is caused by a bacteria known as e-coli, this bacteria enters the body with the blood, once infected by this bacteria the conditions of high fever along with the back pain occurs, the bladder too gets infected by this bacteria. This infection is really fatal and can Read more ...
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Emphysema severity is associated with arterial stiffness in patients with COPD. Similar pathophysiological processes may be involved in both lung and arterial tissue and further studies are now required to identify the mechanism underlying this newly described association.
PneumRx, Inc., a leader in interventional pulmonology, announced today that University Medical Center Groningen has enrolled and treated the first patients in the FDA-approved RENEW pivotal trial to evaluate the RePneu Lung Volume Reduction Coil (LVRC). The RePneu LVRC, a minimally invasive medical implant designed to treat the symptoms of severe emphysema, is intended to improve lung function, exercise ability and quality of life for this underserved patient population.. (Logo: http://photos.prnewswire.com/prnh/20120514/SF06703LOGO) Dr. Dirk-Jan Slebos is the principal trial investigator at UMCG."There is no cure for severe emphysema, and patients have very few options available to relieve their symptoms," he said. "The LVRC is a very exciting technology that has shown great promise in European clinical studies. We have seen significant clinical improvements in treated patients, and we believe this is an important treatment option for many patients with severe emphysema." The RePneu LVRC is ...
Pulmonary emphysema. Frontal computed tomography (CT) scan of a male patients chest showing severe emphysema in the left lung (right). There is a large area of trapped air (black) in the affected lung. Emphysema causes the tiny air sacs of the lungs to become damaged, leading to the walls between them breaking down. This causes large areas of trapped air and leads to a smaller surface area for gaseous exchange, restricting oxygen uptake by the blood. Enlarged air spaces bigger than 1 centimetre in diameter are known as bullae. Lung tissue in bullae may be completely destroyed. The main cause of emphysema is cigarette smoking. Symptoms include a cough and shortness of breath. Bullae may be surgically removed although there is no cure for emphysema. - Stock Image C021/2971
Pulmonary emphysema. Coloured frontal chest X-ray of a male patients chest showing severe emphysema in the left lung (right). There is a large area of trapped air (black) in the affected lung. Emphysema causes the tiny air sacs of the lungs to become damaged, leading to the walls between them breaking down. This causes large areas of trapped air and leads to a smaller surface area for gaseous exchange, restricting oxygen uptake by the blood. Enlarged air spaces bigger than 1 centimetre in diameter are known as bullae. Lung tissue in bullae may be completely destroyed. The main cause of emphysema is cigarette smoking. Symptoms include a cough and shortness of breath. Bullae may be surgically removed although there is no cure for emphysema. - Stock Image C021/2974
COPD is a major public health problem and is pathologically characterized by lung emphysema and bronchial remodeling. Emphysema is defined as an irreversible destruction of alveolar walls and subsequent enlargement of air spaces. New targeted therapies against emphysema are currently developed, thereby stressing the need for non-invasive tools aimed at quantifying emphysema. Multi-slice computed tomography (CT) is the method of reference to quantify emphysema but involves ionizing radiation, thus limiting the possibility of long-term follow-up. MRI is a non-ionizing 3D imaging technique; however, lung MRI is technically challenging with the result that it is currently not used in routine practice. Indeed, both low proton density and susceptibility effects lead to a very low signal intensity derived from lung parenchyma. Recently, pulse sequences with ultrashort echo time (UTE) have been implemented by the use of half radio-frequency excitations and radial projection reconstruction. These UTE ...
Emphysema is a lung disease, which together with chronic bronchitis, is referred to as Chronic Obstructive Pulmonary Disease (COPD). These diseases are characterized by the flow of air in the lungs being obstructed. A major cause of emphysema is smoking but it can be caused by other diseases. In Emphysema the alveoli (the tiny air sacs at the end of airways where gaseous exchange takes place) break down and form much larger sacs. The broken alveoli cause air to get trapped inside the lungs. In severe cases, sections of the lungs can totally collapse causing a pneumothorax, this occurs when air or gas are present in the cavity between the lungs and chest causing the lung to collapse. Imaging in emphysema plays an important part in diagnosis and high resolution computed tomography (HRCT) is especially effective in this process. Emphysema is generally classified into three types according to the area of the lung affected:- centrilobular (or centriacinar), panlobular (or panacinar) and paraseptal. ...
Natural remedies for emphysema are designed to improve lung function, but there are some symptoms that can be relieved in the process. Most of the chronic sufferers of emphysema will experience shortness of breath and difficulty exhaling, and it isnt unusual for chronic sufferers to have an enlarged chest or bluish skin color. The primary goal is to keep the lung function from further deterioration, but it is believed that emphysema is an auto-immune disorder that might be reversible to some extent.. Natural Remedies for Emphysema Includes Avoidance of Certain Environments: If you havent noticed already, natural environmental factors like dust and smoke or smog can aggravate emphysema. If you are a smoker, you need to quit immediately. Unfortunately, if you are still smoking, the condition will only get worse. While this can be a difficult habit to break, there are a number of natural treatments that can help, including hypnosis. Avoid dusty areas and the outdoors on windy days or during ...
The unfortunate result with regard to how long can a person live with Emphysema is that since the air sacs are unable to expand and contract at a normal level less air passes through the lungs and to the rest of the body.. Many persons will inquire prior to asking the question how long can a person live with Emphysema what precisely causes the disease. The disease is normally caused by cigarette smoking although there are some incidences where the disease is thought to be hereditary but this is infrequent. The most common reason a person contracts Emphysema is because he or she smoked cigarettes.. Also before we can answer the question how long can a person live with Emphysema many individuals want to know how a diagnosis is arrived at with regard to the chronic lung disease. Naturally, a diagnosis as to the disease is based on symptoms. Many persons with Emphysema may have symptoms that are mistaken for Asthma however the difference is a patient will wheeze when breathing in with Asthma and the ...
Study Rationale Emphysema is one of the two main components of chronic obstructive pulmonary disease (COPD) and contributes over many years to airway obstruction by the loss of elastic recoil around the smallest airways. Emphysema is induced by cigarette smoking and it is widely accepted that the disease is caused by excessive proteolytic activity by proteases and a chronic inflammatory process, characterized by a cellular influx consisting of macrophages, neutrophils and T cells. This inflammatory response is steroid resistant and leads to slow but persistent alveolar destruction, resulting in enlarged lungs with bullous parts in both lungs. In addition to a central role of innate immunity, recent studies suggest that also (auto)antigen specific immunity may play a role in the pathogenesis of COPD.. Currently, the only treatment available for severe emphysema is lung volume reduction surgery (LVRS) to remove the most destroyed parts of the lungs. The surgery is generally performed in two ...
Pulmonary emphysema is receiving increasing recognition as one of the countrys major health problems. The prevalence of bronchitis and pulmonary emphysema has been estimated as 13 per thousand, meaning that over 2,000,000 people in this country have these diseases. Unfortunately, many American physicians are not sufficiently aware of this problem nor do they understand the pathophysiology of this disease. A book such as Dr. Rosenman has attempted, designed to present in clear and simple terms the essence of pulmonary physiology and describe the abnormal physiology and treatment of pulmonary emphysema, could be a valuable aid to the medical student and ...
Emphysema is a long-term (chronic), irreversible lung disease that occurs when the tiny air sacs in the lungs are damaged, usually as a result of long-term smoking. It causes difficulty breathing and shortness of breath that gets worse over time.. Emphysema is a form of chronic obstructive pulmonary disease (COPD).. A rare type of emphysema is caused by the lack of a substance in the lungs called alpha1-antitrypsin. This type of emphysema is usually inherited.. ...
Emphysema is a long-term (chronic), irreversible lung disease that occurs when the tiny air sacs in the lungs are damaged, usually as a result of long-term smoking. It causes difficulty breathing and shortness of breath that gets worse over time.. Emphysema is a form of chronic obstructive pulmonary disease (COPD).. A rare type of emphysema is caused by the lack of a substance in the lungs called alpha1-antitrypsin. This type of emphysema is usually inherited. ...
Emphysema is a disease of the lungs.. It is one of the diseases that make up chronic obstructive pulmonary disease (COPD). This is a set of diseases where the flow of air in the lungs is obstructed. Emphysema is most often caused by smoking but can be caused by other diseases or have no known cause at all.. It occurs when the very small air sacs (called the alveoli) at the ends of the airways in the lungs start to break down from many sacs to form much bigger sacs. The alveoli are the areas of the lung where oxygen and carbon dioxide are exchanged into and out of the blood. Emphysema makes it hard for people to blow air out of the lungs because air gets trapped inside the broken alveoli due to the collapse of the walls.. There is no cure for emphysema. Treatment includes to stop smoking and taking medicines (broncho-dilators and sometimes corticosteroids). Supplemental oxygen is recommended in those with low oxygen levels at rest. It decreases the risk of heart failure and death if used 15 ...
TY - GEN. T1 - Assessment of multislice CT to quantify pulmonary emphysema function and physiology in a rat model. AU - Cao, Minsong. AU - Stantz, Keith M.. AU - Liang, Yun. AU - Krishnamurthi, Ganapathy. AU - Pressen, Robert G.. PY - 2005. Y1 - 2005. N2 - Purpose: The purpose of this study is to evaluate multi-slice computed tomography technology to quantify functional and physiologic changes in rats with pulmonary emphysema. Method: Seven rats were scanned using a 16-slice CT (Philips MX8000 IDT) before and after artificial inducement of emphysema. Functional parameters i.e. lung volumes were measured by non-contrast spiral scan during forced breath-hold at inspiration and expiration followed by image segmentation based on attenuation threshold. Dynamic CT imaging was performed immediately following the contrast injection to estimate physiology changes. Pulmonary perfusion, fractional blood volume, and mean transit times (MTTs) were estimated by fitting the time-density curves of contrast ...
Emphysema is a kind of chronic obstructive consumptive illness. The air cysts in the lungs become infected and spread. This results in a chronic difficulty breathing and cough. Emphysema is a nature of chronic obstructive pulmonary disorder (COPD). It includes the lack of enlargement and elasticity of the oxygen sacs in the lung. Two of the important indications of emphysema are conciseness of breath and chronic disease. These look in the early stages. This may start only when physical exertion, but as the condition progresses, it can begin to occur while resting, too.. ...
There is a form of Emphysema influenced by a long period of smoking called "Smokers Emphysema". It develops usually in older patients. Another type of Emphysema is the one with a hereditary transmission. In this case there is a deficiency of alpha-i-antitrypsin (AAT), but just one to three percent of all cases of Emphysema are due to AAT deficiency. This happens because in the lungs, at cells level there is an imbalance between elastin and AAT. The reaction between this two proteins is mediate by an enzyme called elastase. When there is a genetic deficiency of AAT the elastin degradation occurs unchecked. This phenomenon is worsen if the patients with genetic deficiency of AAT smoke and the symptoms appears early middle age. The deficiency of ATT is detected by blood tests made in specialized laboratories ...
There is a form of Emphysema influenced by a long period of smoking called "Smokers Emphysema". It develops usually in older patients. Another type of Emphysema is the one with a hereditary transmission. In this case there is a deficiency of alpha-i-antitrypsin (AAT), but just one to three percent of all cases of Emphysema are due to AAT deficiency. This happens because in the lungs, at cells level there is an imbalance between elastin and AAT. The reaction between this two proteins is mediate by an enzyme called elastase. When there is a genetic deficiency of AAT the elastin degradation occurs unchecked. This phenomenon is worsen if the patients with genetic deficiency of AAT smoke and the symptoms appears early middle age. The deficiency of ATT is detected by blood tests made in specialized laboratories ...
Emphysema , , Difficult trunk rotation, , Breathing difficulty, Difficult breathing, Breathlessness, Shortness of breathAbdominal spasms, , Cold hands and feet, Coldness of the four extremities, Coldness of extremities, Xerosis, Dryness of the skin, Skin dryness, Hoarseness, Weak voice, Low voice, Loss of voice emphysema
Looking for centrilobular emphysema? Find out information about centrilobular emphysema. A disorder marked by pulmonary inflation, primarily affecting the respiratory bronchioles and usually more severe in the upper lobes Explanation of centrilobular emphysema
Objective: To determine the impact of endobronchial coils on health-related quality-of-life (HRQoL). This paper utilizes trial data to identify the predictors of HRQoL in patients with severe emphysema, and subsequently estimates the impact of a new treatment on HRQoL (measured by utilities). These utility estimates are used to generate indicative long-term QALY estimates for a range of clinically plausible scenarios as a precursor to cost-effectiveness analyses. Methods: Patient level HRQoL data from RENEW and the National Emphysema Treatment Trial (NETT) were combined and mapped to generic EuroQol 5-dimension health utility questionnaire (EQ-5D) values using a published algorithm. Multilevel statistical models were developed using treatment, time, response, and baseline characteristics (EQ-5D, age, gender, FEV1, lung RV) to predict EQ-5D over time. Lifetime QALY estimates were generated using published survival data from NETT (assuming no impact of treatment on mortality) and four clinically ...
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An elastase-induced emphysema model was utilized to determine if hamsters with preexisting lung disease were more susceptible to lung damage from air-pollutant exposure. Male golden hamsters, divided into two treatment groups, were given a single intratracheal injection of either 6 units of porcine pancreatic elastase (EMP) or buffer (CNT). After a 4-week recovery period, equal numbers of each group were exposed 23 hr/day x 28 day to filtered air (AIR) or to the complex by-products from a dark-phase-reaction mixture of trans-2-butene, ozone, and sulfur dioxide (MIX). Lung-function measurements on the elastase-treated groups showed changes consistent with mild emphysema. There were no significant differences in lung volumes or lung compliance between the AIR- and MIX-exposed animals. However, the nitrogen washout slope decreased and the diffusing capacity for carbon monoxide increased in both the CNT and EMP hamsters exposed to the MIX. The change in diffusing capacity was greater in normal ...
The researchers had 19 volunteers inhale a special kind of "hyperpolarized" helium before they performed two MRI tests of the lungs. Eleven of the volunteers were smokers with no symptoms of emphysema, and the remaining eight were nonsmokers. The first image the researchers acquired showed obstructed areas of the lungs, where the air was unable to pass. The second image they obtained is called an apparent diffusion coefficient (ADC) map, which shows the size of the airspaces in the lungs. Because emphysema increases airspace size, the ADC map shows the location and severity of the disease.. "The ADC maps are very sensitive to changes in the lung structure," Dr. Fain said. "With this tool, it was shown that even smokers that appear healthy have enlarged lung airspaces that suggest emphysema is already developing.". With increasing smoking history, the ADC maps showed progressive breakdown of the lung structure in all regions of the lungs. All smokers with a history greater than 18 pack-years ...
Recent studies have described the combination of both pulmonary emphysema and idiopathic interstitial lung disease (ILDs) by means of high-resolution computed axial tomography (HRCT). Definition of this syndrome was first named by Cottin as combined pulmonary fibrosis and emphysema (CPFE). Functional and radiological findings have showed that these patients are suffering from severe breathlessness, but whose pulmonary functional tests revealed no signs of obstruction, normal static lung volumes, and depressed DLco, most with a history of smoking [1] [2]. The radiological and endoscopic studies especially show that these patients have both areas of upper-lobe predominant emphysema and lesions compatible with fibrosis in both lung bases [3]. No prior research has reported any cases of such condition in person with no prior history of smoking as well as long-term high-dose of glucocorticoid therapy. In this case report, we discuss the presentation, diagnosis, and management of a 53-year-old non-smoker with
This book, edited by two outstanding students of the clinical aspects of pulmonary emphysema, actually consists of a series of essays pertaining to various aspects of the syndrome.. The first half of the book (which, in the reviewers opinion, should be the second half) consists of a series of comprehensive and detailed discussions of the clinical management of pulmonary emphysema, as practiced by Dr. Barach and his group. There is no doubt that most of their beliefs are sound and based on long experience. However, one concept may need questioning. They strongly advocate using oxygen therapy for the hypoxic episodes ...
What percentage of smokers get lung cancer or emphysema - What is the percentage of smokers get lung cancer or emphysema? 15-17% About 15-17% of smokers develop lung cancer or emphysema. About 85% of patients with lung cancer have been exposed to significant amounts of cigarette smoke.
What is Emphysema? Chronic obstructive lung disease caused normally by smoking, leading to abnormal enlargement of air spaces is known as Emphysema. The disease clinically presents by shortness of breath, cough and wheezing which are progressive in nature. Emphysema herbal product by natural herbs clinic is used for the management of this condition. Try Herbal Remedies … Continue reading. ...