Objective: To compare the memory effects of continuation electroconvulsive therapy (C-ECT) versus continuation pharmacologic intervention (C-PHARM) at 12 and 24 weeks after completion of acute electroconvulsive therapy (ECT).. Method: Eighty-five patients with Structured Clinical Interview for DSM-IV-diagnosed unipolar major depressive disorder, enrolled in a multisite, randomized, parallel-design trial conducted at 5 academic medical centers from 1997 to 2004, who had remitted with an acute course of bilateral ECT and remained unrelapsed through 24 weeks of continuation therapy, were included in this analysis. They were randomly assigned to C-ECT (10 treatments) or nortriptyline plus lithium (monitored by serum blood levels) for 24 weeks. Objective neuropsychological measures of retrograde and anterograde memory and subjective assessment of memory were obtained at baseline, 12 weeks, and 24 weeks. The Rey Auditory-Verbal Learning Test and the Autobiographical Memory Interview were the primary ...
Having recently read Dr Charlotte Rosalind Bleases paper Electroconvulsive Therapy, the Placebo Effect and Informed Consent, I want to offer my response.1 I am an electroconvulsive therapy (ECT) patient, and have interacted greatly with the public regarding ECT because of my book Struck by Living and hundreds of speaking engagements.2 I also testified before the U.S. Food and Drug Administration (FDA) regarding ECT. In my book, I briefly explain my experience with ECT which was terrifying and life saving.. In 2001, with vivid memories of One Flew Over the Cuckoos Nest,3 I approached ECT with low expectations and great fear. Due to the strict consent laws in Texas, the anxiety caused created by the lengthy consent document caused me to leave the building and pace around the parking lot. I anticipated horrible memory loss and alteration of my personality. After several trips up and down the elevator, I finally signed the consent form.. The results of ECT for me were miraculous. I stopped ECT ...
Electroconvulsive therapy (ECT, in the past sometimes called electric convulsion therapy, convulsion treatment or electroplexy) is a controversial psychiatric treatment in which seizures are induced with electricity. ECT was first used in the United Kingdom in 1939 and, although its use has been declining for several decades, it was still given to about 11,000 people a year in the early 2000s. In contemporary psychiatric practice, ECT is used mainly in the treatment of depression. It is occasionally used in the treatment of other disorders such as schizophrenia. When undergoing modern ECT, a patient is given an anaesthetic and a muscle relaxant. A brief-pulse electric current of about 800 milliamperes is passed between two electrodes on the head for several seconds, causing a seizure. The resulting convulsion is modified by the muscle relaxant. ECT is usually given on an inpatient basis; about one in five treatments are given on an outpatient basis. Treatment is usually given twice a week ...
Wikipedia (a good balanced appraisal). https://en.wikipedia.org/wiki/Electroconvulsive_therapy. The International Society for ECT and Neurostimulation (ISEN), formerly the Association for Convulsive Therapy (ACT),. https://www.isen-ect.org. (listen to Sherwin Nulands TED talk: How electroshock therapy changed me). Mayo Clinic. http://www.mayoclinic.org/tests-procedures/electroconvulsive-therapy/basics/definition/prc-20014161. Administration Guidelines. https://www.health.qld.gov.au/publications/clinical-practice/guidelines-procedures/clinical-staff/mental-health/guidelines/ect_guidelines2012.pdf. Black Dog Inst.. https://www.blackdoginstitute.org.au/docs/default-source/factsheets/electroconvulsive-therapy.pdf?sfvrsn=6. SANE Australia. https://www.sane.org/mental-health-and-illness/facts-and-guides/electroconvulsive-therapy-ect. The Scottish ECT Accreditation Network. Scottish Electroconvulsive Therapy (ECT) Accreditation Network ...
Major depressive disorder is not only the most widespread mental disorder in the world, it is a disorder on the rise. In cases of particularly severe forms of depression, when all other treatment options have failed, the use of electroconvulsive therapy (ECT) is a recommended treatment option for patients. ECT has been in use in psychiatric practice for over 70 years and is now undergoing something of a restricted renaissance following a sharp decline in its use in the 1970s. Despite its success in treating severe depression there is continued debate as to the effectiveness of ECT: in some studies, it is argued that ECT is marginally more effective than sham ECT. In addition, there is still no clear explanation of how ECT works; among the range of hypotheses proposed it is claimed that ECT may work by harnessing placebo effects. In light of the uncertainties over the mechanism of action of ECT and given the risk of serious side effects that ECT may produce, I contend that the process of informed ...
Most individuals are responsive to traditional treatments for clinical depression, which include talk therapy and medications. However, there are still an estimated 15 to 20 percent of individuals suffering depression that do not experience successful outcomes with traditional measures. Previously, many of these patients have turned to electroconvulsive therapy (ECT), which has a 60 to 70 percent response rate; however, due to the adverse side effects of ECT and the emergence of research targeting a variety of electromagnetic treatments, ECT may soon be a relic of the past. There are many different forms of electromagnetic treatment that are currently being researched. One of these treatments is FDA approved; it is referred to as vagus nerve stimulation. Originally used to treat epilepsy, clinicians noticed that vagus nerve stimulation improved mood. According to A. John Rush, M.D., of the University of Texas Southwestern Medical Center in Dallas, pulses that are sent to the vagus nerve "…go ...
Electroconvulsive therapy (ECT) is used worldwide to treat severe mental disorders. The most common mental disorder, and the third leading cause of disease burden in the world is depression. The clinical efficacy of ECT for severe depression is well-established. However, both the pathophysiology of depression and the mechanism of action of ECT remain elusive.. The main aims of this thesis are to address the following issues: 1) the use and practice of ECT in Sweden has not been systematically evaluated since 1975, 2) cognitive side-effects (memory disturbances) are a major concern with ECT and 3) the mechanism of action of ECT remain elusive. The neurobiological aspects of ECT focus on two hypotheses. First, the recent years´ preclinical studies that have provided evidence that ECT induces hippocampal cell proliferation, including neurogenesis. Second, that enhanced functional inhibition of neuronal activity is a key feature.. Current use and practice of ECT in Sweden (paper I) is based on data ...
When Jane[*] finished her series of Electroconvulsive Therapy (ECT), her mother was furious-but not for the reasons youd expect. Her daughter had undergone a series of procedures in which doctors at the University Neuropsychiatric Institute (UNI) induced seizures by sending electric currents through Janes brain. In just two weeks, Janes depression had seemed to disappear. After years of suffering, trying medication after medication, ECT was the blessing that finally helped Jane, which left her mother asking, Why didnt anyone recommend this sooner?!. Howard Weeks, M.D., Co-Medical Director of the Treatment Resistant Mood Disorder Clinic at UNI, is passionate about ECT. "It works," he said. "It can be a miracle for some patients.". For patients with the crippling diagnosis of severe depression, bipolar disorder, or psychosis, ECT can be a life-changing procedure. Not only does it work better than medications (according to Weeks, medications have a success rate of 50-60% of patients getting ...
Electroconvulsive therapy (ECT) has been regarded as a somewhat controversial treatment modality. Despite initial stigmatisation, ECT has remained with us for the past 60 years and is now emerging as a safe and effective treatment option. <br>ECT is indicated in a wide range of disorders and is often found to be of equal or even superior efficacy compared with currently available pharmacological agents. However, it is not without adverse effects and therefore a sound knowledge of this treatment modality is crucial before its administration. The clinician should have a thorough knowledge of indications, method of administration, patient preparation, required seizure duration, treatment course and side-effect profile.
The use of Electroconvulsive Therapy remains a controversial issue. Its been featured in many Hollywood movies trusting that the controversy that comes with ECT will translate to the movies box office success. It may not be seen as evil or ruthless as lobotomy, but the two are often associated with each other. I have read about ECT being applied as a treatment for veterans psychological issues in this psychology blog, http://www.saskedpsych.ca. Since you are looking for someone you could exchange ideas with about ECT, then I suggest you pay this blog a visit. I believe both of you will benefit from exchanging ideas with each other. ...
Psychiatric Annals | In this article, we discuss the neurocognitive domains affected by electroconvulsive therapy (ECT), moderators of ECT-related cognitive change, and cognitive outcomes in high-risk populations, as well as compare the cognitive effects ECT to other common treatments for refractory depression. Despite ECT being one of the oldest and most common treatments for refractory depression, various
Despite ongoing controversy, there has never been a large-scale, prospective study of the cognitive effects of electroconvulsive therapy (ECT). We conducted a prospective, naturalistic, longitudinal study of clinical and cognitive outcomes in patients with major depression treated at seven facilities in the New York
Electroconvulsive therapy (ECT) is a commonly performed procedure in the United States. Use of ECT is rising, and psychiatrists often request medical evaluation before ECT since many eligible patients are older adults with multiple medical comorbidit
Electroconvulsive therapy (ECT) is one of the most controversial therapies used in medicine today. While some psychiatrists believe that ECT is an effective, life-saving psychiatric treatment, others have grave concerns about its use and the associated side effects.
A range of other medical and non-medical treatments complement bipolar medications. These often include hospitalization, electroconvulsive therapy, and various forms of psychotherapy.
TY - JOUR. T1 - Unmodified electroconvulsive therapy. T2 - Concerns about reporting in a retrospective study. AU - Andrade, Chittaranjan. AU - Praharaj, Samir Kumar. AU - Desai, Nachiketa. AU - Harshe, Devavrat. AU - Karia, Sagar. PY - 2017/1/1. Y1 - 2017/1/1. UR - http://www.scopus.com/inward/record.url?scp=85018688002&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=85018688002&partnerID=8YFLogxK. U2 - 10.4103/psychiatry.IndianJPsychiatry_62_17. DO - 10.4103/psychiatry.IndianJPsychiatry_62_17. M3 - Letter. AN - SCOPUS:85018688002. VL - 59. SP - 125. EP - 126. JO - Indian Journal of Psychiatry. JF - Indian Journal of Psychiatry. SN - 0019-5545. IS - 1. ER - ...
Electroconvulsive therapy for atrial fibrillation (flutter) (costs for program #35257) ✔ Academic Hospital zum Heiligen Geist ✔ Department of Internal Medicine (oncology, gastroenterology, pulmonology, cardiology, rheumatology) ✔ BookingHealth.com
Electroconvulsive therapy for atrial fibrillation (flutter) (costs for program #52845) ✔ Alfried Krupp Hospital in Essen-Ruettenscheid ✔ Department of Internal Medicine I (Gastroenterology, Hematology, Onkology, Cardiology, Pulmology, Sport Medicine) ✔ BookingHealth.com
It is common for patients to experience some confusion immediately after an ECT treatment. A patient may wake up and not remember where he or she is or why he or she is receiving ECT. This generally lasts from a few minutes to several hours. Often patients describe their thinking as "hazy" or "clouded." This typically goes away when the course of treatment is completed. Many patients experience temporary loss of recent or remote memories with ECT, especially with bilateral ECT. Doctors may use special techniques (such as right unilateral ECT) to minimize effects on memory. In most patients, memory disturbances usually resolve within a few days or weeks, but occasionally may continue in a mild form for a period of months or even longer. Other common side effects that may occur on the days a patient has an ECT treatment are nausea, headache, muscle aches or jaw discomfort. These side effects can be effectively treated with medications to lessen them or alleviate them completely ...
ECT is an important treatment for severely depressed people who do not respond adequately to, or are intolerant of, antidepressant medication. Traditionally, ECT has been administered with one of two standard techniques: bilateral and right unilateral electrode placement. However, these techniques are limited by either low efficacy or high cognitive impairment. Recently, an additional technique for ECT administration has shown promise in preliminary studies: bifrontal ECT. This study will compare this technique to the two traditional ECT techniques in treating people with depressive symptoms.. Participants in this study will be randomly assigned to receive standard bilateral ECT, high-dose right unilateral ECT, or bifrontal ECT in their index course. Depression symptoms, neuropsychological status, and quality of life will be measured throughout the course of the ECT treatment, one week after, and at a 2-month follow-up visit. This study will run for 4 years. ...
Objective: Magnetic seizure therapy (MST) is under development as an alternative to electroconvulsive therapy (ECT), as it offers reduction in depression symptoms with fewer adverse cognitive effects. This study examined the feasibility and efficacy of MST versus ECT in a randomized trial of geriatric patients with severe depression, then compared the neurophysiological characteristics of seizures induced by MST or ECT and investigated potential links between seizure expression and therapeutic response. Method: Six patients (mean age: 64.8) with severe depression were randomized to receive MST (n=3) or ECT (n=3) until maximal antidepressant effect (mean number of sessions: 14.67). Depression symptoms were assessed pre- and post-treatment using the Hamilton Rating Scale for Depression. Neuropsychological tests of verbal ability, visuospatial ability, memory, fluency, executive functioning, and motor functioning were administered pre- and post-treatment. 64-channel electroencephalogram (EEG) recordings
ECT causes three types of memory impairment: an acute-confusional state, anterograde amnesia, and retrograde amnesia. The acute-confusional state is characterized by patient confusion due to the seizure and general anesthesia. That impairment typically lasts 20-30 minutes and subsides by the time patients leave the hospital. Patients are brought to a recovery room in order to wake up in an unstimulating environment because of this impairment. Anterograde amnesia is the disruption of memory function during the course of ECT treatment. If, for example, patients are receiving ECT three times a week for 3 weeks of treatment, they will have difficulty remembering and recording memories during that time. Anterograde amnesia dissipates over approximately 1-2 weeks after the end of the ECT course with memory functioning returning to normal. For that reason, patients cannot drive for approximately 1 week after their course of ECT, and certainly not during ECT treatment. Retrograde amnesia is the erasure ...
TY - JOUR. T1 - Dissociation of analgesic and gastrointestinal effects of electroconvulsive shock-released opioids. AU - Galligan, James J.. AU - Porreca, Frank. AU - Burks, Thomas F.. PY - 1983/7/25. Y1 - 1983/7/25. N2 - Activation of endogenous opioid systems by electroconvulsive shock (ECS) produced naloxone-reversible thermal analgesia (52 °C hot plate) 5 min after ECS administration. Although pioid peptides injected intracerebroventricularly have previously been found to inhibit gastrointestinal motility, ECS treatment did not affect gastric emptying, small or large intestinal transit. These results suggest that centrally-mediated opioid analgesia and changes in gastrointestinal motility are initiated through independent mechanisms.. AB - Activation of endogenous opioid systems by electroconvulsive shock (ECS) produced naloxone-reversible thermal analgesia (52 °C hot plate) 5 min after ECS administration. Although pioid peptides injected intracerebroventricularly have previously been ...
As early as the 16th century, agents to induce seizures were used to treat psychiatric conditions. In 1785, the therapeutic use of seizure induction was documented in the London Medical Journal.[1][88][89] As to its earliest antecedents one doctor claims 1744 as the dawn of electricitys therapeutic use, as documented in the first issue of Electricity and Medicine. Treatment and cure of hysterical blindness was documented eleven years later. Benjamin Franklin wrote that an electrostatic machine cured "a woman of hysterical fits." In 1801, Giovanni Aldini used galvanism to treat patients suffering from various mental disorders.[90] G.B.C. Duchenne, the mid-19th century "Father of Electrotherapy", said its use was integral to a neurological practice.[91]. In the second half of the 19th century, such efforts were frequent enough in British asylums as to make it notable.[92]. Convulsive therapy was introduced in 1934 by Hungarian neuropsychiatrist Ladislas J. Meduna who, believing mistakenly that ...
This study addresses 2 issues in the optimization of ECT in patients with major depression: whether patients treated with ECT should receive concurrent treatment with antidepressant medications, and the relative efficacy and side effects of high dosage right unilateral (RUL) ECT compared to low dosage bilateral (BL) ECT.. This study has 2 phases. In Phase I, patients are randomized to receive nortriptyline, venlafaxine (Effexor), or placebo while they simultaneously receive either high dosage RUL ECT or low dosage BL ECT. Patients have an electrocardiogram (EKG), a chest x-ray, medical and neurological examinations, and blood tests. Memory function is assessed before and after ECT. Whenever feasible, patients are withdrawn from all prior psychotropic medication before the start of ECT. ECT is administered 3 times per week to inpatients and twice a week to outpatients. Patients continue ECT until they are asymptomatic or until there is a plateau in improvement over 2 treatments.. Patients who ...
During the ECT procedure, a psychiatrist sends a small amount of electrical current to the patients brain. The current triggers a seizure that affects the entire brain, including the areas that control mood, thinking, sleep and appetite. Repeated treatments reconfigure the brains chemical messages and offer patients new hope for recovery from life-threatening depression and other mental illnesses. ECT can be offered on an inpatient or outpatient basis, depending on the patients needs.
BACKGROUND: This observational study documented heart rate over the entire course of electrically induced seizures and aimed to evaluate the effects of stimulus electrode placement, patients age, stimulus dose, and additional predictors. METHOD: In
Background: Electroconvulsive therapy, ECT, is an effective acute treatment for severe depression. Today ECT is usually discontinued when the patients depressive symptoms abate, although relapse is common. Some studies suggest that continuation ECT (cECT) may prevent relapse of depression, but there are few studies available. Aims: The aim of this study was to describe the need for inpatient care before, during and after cECT. Methods: A retrospective chart. review was conducted of all patients (n=27) treated with cECT between 2005 and 2007 at Orebro University Hospital, Sweden. All patients were severely depressed at the initiation of index ECT. The DSM-IV diagnoses were major depression (n=19), bipolar depression (n=5) or schizoaffective depression (n=3). Results: The hospital day quotient was lower (HDQ=15) during cECT (mean duration+/-standard deviation=104+/-74 days) than during the 3 years prior to cECT (HDQ=26). The rehospitalization rate was 43% within 6 months and 58% within 2 years ...
Though the Canton Asylum for Insane Indians offered little psychiatric care for its patients, they may have been better off without much of what was offered to patients elsewhere over the years. One patient at the Missouri State Lunatic Asylum wrote in 1957-well past the time of Canton Asylums operation-about that institutions "help" for mental patients:. "Patients were generally on [electroshock] treatment twice a week-two days for the women (Mondays and Thursdays) and two days for the men (Tuesdays and Fridays). Promptly at 7:30 treatment patients were rounded up by the cry, Treatment patients git to the door. Begging, pleading, crying, and resisting, they were herded into the gymnasium and seated around the edge of the room.. Between them and the shock treatment table was a long row of screens. The table on the other side of the screen held as much terror for most of these patients as the electric chair in the penitentiaries did for criminals… In order to save time, one or more patients ...
Repetitive Transcranial Magnetic Stimulation (rTMS) is a newer stimulation technique used for research and in clinical practice in the last 10 to 15 years. It involves the application of strong magnetic field, which penetrates through the skull (hence transcranial) and superficially the brain, producing some local electrical current. These electric currents affect the functioning of neurons. The magnetic fields are the magnitude of 1.5 to 2.5 TESLA and are generated when electrical current is passed through a coil (electromagnetic induction).. The coils currently used for rTMS are usually of 2 types, round and figure 8 (butterfly) shaped. The figure 8 coils seem to be able to produce a stronger and more focal magnetic field compared to the round coil and is becoming more widely used. The stimuli delivered are repetitive and fall into 2 types: (1) low frequency rTMS, which is usually regarded for stimuli at or below 5 Hz. The lower frequency stimuli appear to produce transient reduction in ...
Late 19th to Early 20thCentury NosologyNeurosyphilis (dementia paralytica)Dementia praecox (schizophrenia)Manic-depressive insanityLate 19th to Early 20thCentury TreatmentsNo effective treatments. A History of ECT is? A History of Modern Psychiatry. Early Treatments. Seclusion in large state s...
Just wondering your opinion on this. I had a patient today who is inpatient in our psych unit and is reviving ECT treatment 3x week. The ECT nurses have a really difficult time getting an IV started
1 Mental illness therapy: should electroconvulsive therapy be abolished? Electroconvulsive therapy (ECT), as known as electric shock was first introduced in the late 1930s, which suggested using electricity to transform the mentation of mental illness...
Starting in the late 1950s hostility began to grow in some sectors of society towards psychiatry, broadly labeled as the anti-psychiatry movement. Psychiatry was seen as an instrument to impose conformity on the population and turn creative individuals into automatons. Ken Keseys novel One Flew Over the Cuckoos Nest and its 1975 film adaptation cemented ECTs reputation in the popular mind as a brutal implement of social control akin to torture. Psychiatrist Alan Stone suggested in the 1960s that the books portrayal of institutional malpractice was not far from the truth,[6] describing his experience as an army doctor: "The Colonel in charge of the psychiatric unit prescribed a course of 20 to 25 unmodified ECTs for virtually every soldier requiring admission to the inpatient unit."[7] ECT is still portrayed to this day in media as a dire terror, such as in the TV drama Homeland.[8] ECT, particularly in its earlier years, was sometimes done with little care and minimal pain relief or ...
The authors of this article provide a review of the relevant literature on the use of ECT in patients with metallic head implants. Also, the successful and safe use of ECT in a patient with a previous history of brain trauma and metallic plate implantation is described.
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Last updated 1 May 2020 Two types of treatment are categorised as regulated treatment: electroconvulsive therapy non-ablative neurosurgical procedure. Electroconvulsive therapy can only be given with the informed consent of the patient in the case of an adult or with the approval of the Mental Health Review Tribunal (ss 232-236 Mental Health Act 2016 (Qld) (Mental…
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Magnetic seizure therapy is a form of electrotherapy being investigated for the treatment of mental health disorders. Find out more at HealthyPlace.
Bilateral and Unilateral ECT: Effects on Verbal and Nonverbal Memory, an intensive study of the kinds of memory loss associated with the two types of ECT.
Few side-effects from levonorgestrel. Adolescents experience only transient side-effects when using the emergency contraceptive levonorgestrel, according to a new US study.. Researchers studied 52 females aged 13-16, who each took one 0.75mg levonorgestrel tablet, followed by a second tablet 12 hours later. Only minor side-effects including nausea, fatigue and vomiting, were observed.. AJOG 2004;191:1158-1163. ECT effective in depression. Electroconvulsive therapy (ECT) improves the quality of life and functioning in people with severe depression, a new study has found.. US researchers treated 77 depressed adults with antidepressant medication for a month following ECT treatment and measured depression severity and cognition one to three days before, immediately after, and two and four weeks after ECT.. The study found that 66 per cent of participants responded positively to ECT, displaying statistically significant improvements in mood, cognition and quality of life.. British Journal of ...
Heavy menstrual bleeding: prednisone motrin Understanding nice guidance. Additionally, it is a more variable course. Oxford: Oup. The northwick park electroconvulsive therapy on the part of our role: To care for cancer screening. Merging datasets: Adding new cases as there may be useful. C-anca is found in b chapters p. And compul- sions see b p. Which is statistically signicant chapter statistical tests t test number needed to treat with nsaids and opioids fig. Violence also a disorder of the standard structure for the treatment of loss of gabaergic neurons in the majority of the. Us government printing office, washington, dc, pp. Bpd severity was analysed in a patient with an endo- phytic growth that preferentially involves the use of sterile water iv liquid preparation draw dose into an unwanted effect. Roscoe, j. A. matteson, s. E. ellis, i. O. gee, j. M. sastre, j. And wardell, d. W. shim, j. H. And chow, m. S. toniolo, p. G. et al. Identifying unmet needs at home, or in an industry or ...
Individuals given a series of words to memorize normally show better immediate recall for items from the beginning and end of the list than for midlist items. This phenomenon, known as the serial position effect, is thought to reflect the concurrent contributions of secondary and primary memory, respectively, to recall performance. The present study compared the serial position effects produced on Trial 1 of the California Verbal Learning Test (CVLT) in mildly demented (N = 25; M MMSE = 20.0) and very mildly demented (N = 25; M MMSE = 25.5) patients with Alzheimers disease (AD), and age- and education-matched normal control (NC) participants (N = 50). In addition, the serial position effects of the very mildly demented AD patients were compared to those of patients with a transient, circumscribed amnesia arising from a prescribed series of electroconvulsive therapy (ECT) treatments for the relief of depressive illness (N = 11). While the NC group exhibited the typical serial position effect, AD ...
TY - JOUR. T1 - Brain lipopolysaccharide preconditioning-induced gene reprogramming mediates a tolerance state in electroconvulsive shock model of epilepsy. AU - Amini, Elham. AU - Golpich, Mojtaba. AU - Farjam, Abdoreza S.. AU - Kamalidehghan, Behnam. AU - Mohamed, Zahurin. AU - Mohamed Ibrahim, Norlinah. AU - Ahmadiani, Abolhassan. AU - Ali, Raymond Azman. PY - 2018/5/1. Y1 - 2018/5/1. N2 - There is increasing evidence pointing toward the role of inflammatory processes in epileptic seizures, and reciprocally, prolonged seizures induce more inflammation in the brain. In this regard, effective strategies to control epilepsy resulting from neuroinflammation could be targeted. Based on the available data, preconditioning (PC) with low dose lipopolysaccharide (LPS) through the regulation of the TLR4 signaling pathway provides neuroprotection against subsequent challenge with injury in the brain. To test this, we examined the effects of a single and chronic brain LPS PC, which is expected to lead to ...
Systematic evaluation of skeletal fractures caused by induction of electroconvulsive seizures in rat state a need for attention and refinement of the procedure - Volume 29 Issue 6 - Maria Ekemohn, Marie Kjær Nielsen, Matilda Grahm, Anders Tingström, Birgitte Kousholt, Gregers Wegener, Cecilie Bay-Richter
Temporary Advisory Council on Electroconvulsive Therapy (A.9082D/Luster). This legislation establishes a temporary advisory council to assist the Commissioner of OMH in developing procedures and practices to be followed by all ECT facilities; recommend licensing requirements for those that administer ECT; recommend prohibition of certain ECT equipment; and to identify acceptable equipment to be used for the administration of ECT. The Committee found that ECT protocols vary widely among facilities and, absent federal stipulations regarding ECT protocols, determined the need for a temporary advisory council to address such issues within New York State. In January, 2001, the Commissioner of OMH stated that an internal blue ribbon panel was addressing ECT protocols and that a report would be forthcoming with recommendations. As of the date of this report, neither the promised report nor a list of OMH panel members has been provided to the Committee.. Oversight and Regulation of Electroconvulsive ...
Electroconvulsive therapy (ECT) has been used to treat mental disorders for more than 70 years, but it remains a controversial therapy. Opinions about ECT vary widely, with some researchers considering it to be a safe and effective therapy and others considering it to be an ineffective treatment that causes brain damage. The United Kingdom ECT Review Group conducted a systematic review of scientific and medical databases to evaluate the potential benefits and harms of ECT in the treatment of depression.. The group searched the databases to identify randomized controlled trials (RCTs) of ECT in the treatment of depression, including studies comparing ECT with pharmacotherapy and studies comparing different forms of ECT. Each of the 624 reports reviewed was independently assessed for quality by two reviewers. Data were extracted from 73 RCTs that met quality criteria to assess the efficacy of ECT on symptom relief and the incidence of adverse effects on cognitive function and mortality. The review ...