Dioxins and dioxin-like compounds (DLCs) are compounds that are highly toxic environmental persistent organic pollutants (POPs). They are mostly by-products of various industrial processes - or, in case of dioxin-like PCBs and PBBs, part of intentionally produced mixtures. They include: Polychlorinated dibenzo-p-dioxins (PCDDs), or simply dioxins. PCDDs are derivatives of dibenzo-p-dioxin. There are 75 PCDD congeners, differing in the number and location of chlorine atoms, and seven of them are especially toxic, the most dangerous being 2,3,7,8-Tetrachlorodibenzodioxin (TCDD) Polychlorinated dibenzofurans (PCDFs), or furans. PCDFs are derivatives of dibenzofuran. There are 135 isomers, ten have dioxin-like properties. Polychlorinated/polybrominated biphenyls (PCBs/PBBs), derived from biphenyl, of which twelve are dioxin-like. Under certain conditions PCBs may form dibenzofurans/dioxins through partial oxidation. Finally, dioxin may refer to 1,4-Dioxin proper, the basic chemical unit of the ...
Dioxins and dioxin-like polychlorinated biphenyls (DL-PCBs) are hazardous toxic, ubiquitous and persistent chemical compounds, which can enter the food chain and accumulate up to higher trophic levels. Their determination requires sophisticated methods, expensive facilities and instruments, well-trained personnel and expensive chemical reagents. Ideally, real-time monitoring using rapid detection methods should be applied to detect possible contamination along the food chain in order to prevent human exposure. Sensor technology may be promising in this respect. This review gives the state of the art for detecting possible contamination with dioxins and DL-PCBs along the food chain of animal-source foods. The main detection methods applied (i.e., high resolution gas-chromatography combined with high resolution mass-spectrometry (HRGC/HRMS) and the chemical activated luciferase gene expression method (CALUX bioassay)), each have their limitations. Biosensors for detecting dioxins and related compounds,
Dioxins and dioxin-like polychlorinated biphenyls (DL-PCBs) are hazardous toxic, ubiquitous and persistent chemical compounds, which can enter the food chain and accumulate up to higher trophic levels. Their determination requires sophisticated methods, expensive facilities and instruments, well-trained personnel and expensive chemical reagents. Ideally, real-time monitoring using rapid detection methods should be applied to detect possible contamination along the food chain in order to prevent human exposure. Sensor technology may be promising in this respect. This review gives the state of the art for detecting possible contamination with dioxins and DL-PCBs along the food chain of animal-source foods. The main detection methods applied (i.e., high resolution gas-chromatography combined with high resolution mass-spectrometry (HRGC/HRMS) and the chemical activated luciferase gene expression method (CALUX bioassay)), each have their limitations. Biosensors for detecting dioxins and related compounds,
Dioxins refers to a group of persistent chlorinated chemical compounds that have similar chemical structures and properties, and have similar biological characteristics, including toxicity. Food Standards Australia New Zealand (FSANZ) has conducted an analytical survey of dioxins in a range of food sampled in Australia with the purpose of assessing the level of risk to human health associated with the dietary exposure of the Australian population to dioxins. The overall conclusion of this report is that, on the basis of the available data, taking into account all the inherent uncertainties and limitations, the public health and safety risk for all Australians from exposure to dioxins from foods is very low.. Dioxins includes the polychlorinated dibenzodioxins (PCDDs or dioxins), the closely related polychlorinated dibenzofurans (PCDFs or furans) and polychlorinated biphenyls (dioxin-like PCBs, or PCBs). These compounds can accumulate in the body fat of animals and humans and have a tendency ...
TY - JOUR. T1 - Concentrations of dioxins and other organochlorines (PCBs, DDTs, HCHs) in human milk from Seveso, Milan and a Lombardian rural area in Italy. T2 - A study performed 25 years after the heavy dioxin exposure in Seveso. AU - Weiss, J.. AU - Päpke, O.. AU - Bignert, A.. AU - Jensen, S.. AU - Greyerz, E.. AU - Agostoni, C.. AU - Besana, R.. AU - Riva, E.. AU - Giovannini, M.. AU - Zetterström, Rolf. PY - 2003/4/1. Y1 - 2003/4/1. N2 - Aim: To investigate whether those who were exposed to high levels of the dioxin TCDD 25 years ago in Seveso, northern Italy still have higher than the expected levels of dioxins in their fat stores, and to investigate the concentrations of dioxins in the breast milk of mothers in Seveso and in two other regions in Italy. The load of vertically transmitted dioxins to the next generation, if being breastfed, was also investigated. Methods: As there may be a synergistic effect of mixtures of organic chlorines, the concentrations of pesticides such as DDTs ...
Dioxins and polychlorinated biphenyls (PCBs) are toxic chemicals that persist in the environment and accumulate in the food chain. Their presence in the environment in Europe has declined since the 1970s, following concerted efforts by public authorities and industry.. In the context of EFSAs work, dioxins refers to two groups of compounds: Polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs). Dioxins have no technological or other use, but are generated in a number of thermal and industrial processes as unwanted and often unavoidable by-products. In contrast to dioxins, PCBs had widespread use in numerous industrial applications, and were produced in large quantities for several decades with an estimated total world production of 1.2-1.5 million tonnes, until they were banned in most countries by the 1980s.. Dioxins and PCBs are found at low levels in many foods. Longer-term exposure to these substances has been shown to cause a range of adverse effects on the nervous, immune ...
Dioxins and polychlorinated biphenyls (PCBs) are toxic chemicals that persist in the environment and accumulate in the food chain. Their presence in the environment in Europe has declined since the 1970s, following concerted efforts by public authorities and industry.. In the context of EFSAs work, dioxins refers to two groups of compounds: Polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs). Dioxins have no technological or other use, but are generated in a number of thermal and industrial processes as unwanted and often unavoidable by-products. In contrast to dioxins, PCBs had widespread use in numerous industrial applications, and were produced in large quantities for several decades with an estimated total world production of 1.2-1.5 million tonnes, until they were banned in most countries by the 1980s.. Dioxins and PCBs are found at low levels in many foods. Longer-term exposure to these substances has been shown to cause a range of adverse effects on the nervous, immune ...
Dioxins are extremely widespread, toxic and persistent pollutants, as well as a major concern for human health. The Aryl hydrocarbon receptor (Ahr) is the key component in the metabolic response to dioxins. Ahr is a cytoplasmic bHLH-PAS transcription factor that, upon binding with dioxin, translocates to the nucleus. There it forms a complex with the Ah receptor nuclear transloator (Arnt), another bHLH-PAS protein, and binds to the eight-nucleotide XRE motif to control gene expression. Previous work with Ahr knock-out mice revealed the existence of dioxin-independent activity for Ahr in development, but the relationship between the two activities of Ahr remains unclear. Our work uses Drosophila to clarify this question, which is central for therapies seeking inactivation of Ahr. The Drosophila Ahr homologue, spineless(ss), does not bind dioxins, however, it physically interacts with Tango (Tgo), Arnts fly homologue, and controls gene expression through the XRE motif during development. Here I ...
Industrial activities: Dioxin is not produced or used commercially in the United States. It is a contaminant formed during the production of some chlorinated organic compounds, including a few herbicides such as Silvex. Over the past decade, EPA and industry have been working together to dramatically reduce the production of dioxin and its release to the environment.. Although environmental levels of dioxins have decreased in the last 30 years, dioxins are extremely persistent compounds and break down very slowly. In fact, a large part of current exposures to dioxins in the United States is due to releases that occurred decades ago (e.g., pollution, fires).. Even if all human-generated dioxins were eliminated, low levels of naturally produced dioxins would remain. EPA and its government partners are looking for ways to further reduce dioxins entering the environment and to reduce human exposure to them.. Other ways dioxins are produced:. Burning: Combustion processes such as waste incineration ...
Maximum levels set by the European Commission for thesum of dioxins (WHO-PCDD/F-TEQ) for marine oils (fish body oil, fish liver oil and oils of other marine organisms intended for human consumption): 1.75 ng/kg fat. #Maximum levels set by the European Commission for thesum of dioxins and dioxin like PCBs (WHO-PCDD/F-PCB-TEQ) for marine oils (fish body oil, fish liver oil and oils of other marine organisms intended for human consumption): 6.0 ng/kg fat. # Dioxins (sum of polychlorinated dibenzo-para-dioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs), expressed as World Health Organisation (WHO) toxic equivalent using the WHO-toxic equivalency factors (WHO-TEFs)) and sum of dioxins and dioxin-like PCBs (sum of PCDDs, PCDFs and polychlorinated biphenyls (PCBs), expressed as WHO toxic equivalent using the WHO-TEFs). WHO-TEFs for human risk assessment based on the conclusions of the World Health Organization (WHO) - International Programme on Chemical Safety (IPCS) expert meeting which was ...
All groups of dioxin-like compounds are persistent in the environment.[61] Very few soil microbes nor animals are able to break down effectively the PCDD/Fs with lateral chlorines (positions 2,3,7, and 8). This causes very slow elimination. However scientists at Martin Luther University recently found that a type of bacteria Dehalococcoides CBDB1 can extract the chlorine from dioxin compounds in the absence of oxygen.[62][63] Ultraviolet light is able to slowly break down these compounds. Lipophilicity (tendency to seek for fat-like environments) and very poor water solubility make these compounds move from water environment to living organisms having lipid cell structures. This is called bioaccumulation. Increase in chlorination increases both stability and lipophilicity. The compounds with the very highest chlorine numbers (e.g. octachlorodibenzo-p-dioxin) are, however, so poorly soluble that this hinders their bioaccumulation.[61] Bioaccumulation is followed by biomagnification. Lipid-soluble ...
An urgent review is underway after an ABC Four Corners investigation found elevated levels of dangerous dibenzo-para-dioxins - dioxins - in a generic version of 24D, one of Australias most widely used herbicides. 2,4-D is used in many commercial products including; Bayer All-In-One, Nufarm, Kuziherb, Hi-Yield, Weedtrine, Aqua-Kleen, Barrage, Plantgard, Lawn-Keep, Planotox, Malerbane, Speedzone and Dupont 24D. While this latest scare focuses on commercially used chemicals, it is likely that domestic-use herbicides and pesticides contain the same dioxins.. Dioxins are one of the most toxic chemical compounds in the world - Australian authorities dont routinely test for them - dioxins break down extremely slowly in the environment, they bioaccumulate - collect in fatty tissue - becoming concentrated in animals higher up the food chain. Dioxins are almost exclusively man-made. In herbicides 2,4-D is used widely to control many types of broadleaf weed, and belongs to the Dirty Dozen Persistent ...
INDIUM: One of the common reasons for halogen elimination in electronics is based around the possibility that halogens can form dioxins when that halogenated product is burned. Dioxins are...
Survey Methodology. The principal mechanism for the entry of dioxins into the environment in Ireland is by low-level emissions from multiple combustion sources to the atmosphere, with subsequent deposition onto vegetation such as grass. Any dioxins on grass ingested by cows tend to concentrate in the milk fat. Hence, sampling for dioxin levels in the milk of grazing cows is the approach adopted. The survey was carried out between June and early August 2011, during the peak outdoor grazing season, by taking a series of milk samples mainly from representative regional dairies. Additional samples were also taken from localities that might be seen as areas of potential risk of raised dioxin levels.. The WHO Toxic Equivalent is the current internationally recognised system for comparing dioxin toxicities of different samples. Samples were tested for dioxins only and for dioxins and PCBs combined and the levels found were well below the EU limit in milk and milk products. In view of the increased ...
TY - JOUR. T1 - Dioxin exposure and age of pubertal onset among Russian boys. AU - Korrick, Susan A.. AU - Lee, Mary M.. AU - Williams, Paige L.. AU - Sergeyev, Oleg. AU - Burns, Jane S.. AU - Patterson, Donald G.. AU - Turner, Wayman E.. AU - Needham, Larry L.. AU - Altshul, Larisa. AU - Revich, Boris. AU - Hauser, Russ. PY - 2011/9/1. Y1 - 2011/9/1. N2 - Background: Animal data demonstrate associations of dioxin, furan, and polychlorinated biphenyl (PCB) exposures with altered male gonadal maturation. It is unclear whether these associations apply to human populations. bjectives: We investigated the association of dioxins, furans, PCBs, and corresponding toxic equivalent (TEQ) concentrations with pubertal onset among boys in a dioxin-contaminated region. ethods: Between 2003 and 2005, 499 boys 8-9 years of age were enrolled in a longitudinal study in Chapaevsk, Russia. Pubertal onset [stage 2 or higher for genitalia (G2+) or testicular volume (TV) , 3 mL] was assessed annually between ages 8 ...
NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41 LAB: Battelle Columbus TOXIC EQUIVALENCY FACTOR EVALUATION(PECDF) DATE: 07/14/03 EXPERIMENT: 96007 TEST: 05 TIME: 14:21:29 CAGES FROM 0000 TO LAST CAGE PAGE: 1 TEST TYPE: CHRONIC ROUTE: GAVAGE NTP: C96007F ------------------------------------------------------------------------------------------------------------------------------------ REASONS FOR REMOVAL: ALL REMOVAL DATE RANGE: ALL TREATMENT GROUPS: INCLUDE ALL NTP MEAN BODY WEIGHTS AND SURVIVAL TABLE REPORT: EISRPT41 LAB: BATTELLE COLUMBUS TOXIC EQUIVALENCY FACTOR EVALUATION(PECDF) DATE: 07/14/03 EXPERIMENT: 96007 TEST: 05 TIME: 14:35:48 SPECIES: RATS, SPRAGUE-DAWLEY TEST TYPE: TWO YEAR ROUTE: ORAL GAVAGE NTP: 96007F CONT: NO1-ES-75411 CAS: 57117-31-4 MEAN BODY WEIGHTS AND SURVIVAL OF FEMALE RATS IN THE TWO YEAR ORAL GAVAGE STUDY OF TOXIC EQUIVALENCY FACTOR EVALUATION(PECDF) ...
The Minnesota Department of Health (MDH) has prepared this memo in response to your January 28, 2003, request for guidance on dioxin, as well as to identify a consistent approach for agencies and programs to assess the carcinogenic health risks from exposure to dioxin-like compounds. Guidance for assessing the noncancer health risks is still under development and will not be addressed in this memo. Because of the uncertainties associated with the toxicities of dioxin mixtures, MDH uses a conservative approach to evaluate potential risks. As more data become available, MDH re-evaluates and revises its risk assessment methods and procedures, as appropriate. Dioxin-like Compounds. The term dioxins is used to refer to a family of complex but related chlorinated compounds with similar chemical structures and biological activity. The polychlorinated dibenzo-p-dioxins (PCDDs) include 75 individual compounds, the polychlorinated dibenzofurans (PCDFs) include 135 individual compounds, and the ...
compliance testing with regard to the action levels and maximum levels for dioxins, dioxin-like PCBs and non-dioxin-like PCBs Recommendation 2014/633/EU. Feed:
Three Case Studies from Mad Cows and Mothers Milk: Dioxins, or Chemical Stigmata; Hamburger Hell; & Mothers Milk By: Cameron A. Straughan June 29, 2002 I chose to read Mad Cows and Mothers Milk mainly because it deals in depth with risk communication concerning PCBs and Dioxins - something I have had ample experience with.…
Dioxins are a group of persistent environmental pollutants (POPs) that comprise of chlorinated organic chemicals. These airborne particles can deposit on plants or in water, and animals can accumulate these highly toxic molecules in their fat.
To gather the droplets, Dr Hanano and his colleagues first softened up their date stones by soaking them in water for two weeks. That done, they ground them up and centrifuged the result. This process separated the droplets from the rest of the gunk as a creamy emulsion. It was then a question of testing the emulsions ability to extract dioxins from water. As the group report in Frontiers in Plant Science, it did this well. The droplets phospholipid membranes proved no barrier to the passage of dioxins, which accumulated satisfactorily in the oil. One of Dr Hananos collaborators, Denis Murphy of the University of South Wales, in Britain, describes the droplets as acting like little magnets for dioxins. Within a minute, he says, virtually all the dioxins are sucked out of a solution. It is very fast. ...
As the measurements of PCDD/PCDFs are complex, there is no reliable estimation of emissions in most of low- and middle-income countries. In order to help countries identify sources of emissions and to estimate release of PCDD/PCDFs, the United Nations Environment Program (UNEP) has established a Toolkit for Identification and Quantification of Releases of Dioxins, Furans and Other Unintentional Persistent Organic Pollutants (POPs) [21, 22]. The main objective of the Toolkit is to estimate the PCDD/PCDFs emissions from existing sources to the air, water, land, residue, and other products [22]. Therefore, emissions of PCDD/PCDFs were estimated by the methods proposed by the UNEP Toolkit, which consists of five-steps [21-23]. They are 1) the use of screening matrix to identify the major source categories of PCDD/PCDFs, 2) controlling subcategories to determine present activities and sources in the country, 3) collection of detailed information on the processes and classifying processes into similar ...
In preparation for a study of the relative oral bioavailability of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) in soils (typically containing less than 1 ppb 2,3,7,8-tetrachlorodibenzo-p-dioxin [TCDD] toxic equivalents [TEQ]), the background concentrations of PCDD/ Fs and selected polychlorinated biphenyls (PCBs) were measured in liver and adipose tissue from female Sprague-Dawley rats and juvenile swine after 30 d of ingesting laboratory chow. The measured concentrations of TCDD and other PCDD/Fs in rat livers were severalfold less than previously reported in the literature for control (unexposed) laboratory rodents. The concentrations of PCDD/Fs and selected PCBs in livers of swine were three- to fourfold lower than those reported for rats. The lower concentrations found in this study compared to previous findings may be due to inadvertent laboratory contamination in previous studies or to declining levels of PCDD/Fs in laboratory feed, which parallel the declines in ...
MONDAY, Dec. 30, 2019 (HealthDay News) -- Decades-banned pesticides apparently continue to interfere with fetal growth during U.S. pregnancies, a new study reports.. DDT was banned in 1972 in the United States, but low levels of it and other organic chemical pollutants can still be found in the blood of pregnant American women, researchers reported online Dec. 30 in JAMA Pediatrics.. Women carrying even low levels of these pollutants had slightly smaller fetuses than women whose exposure to the chemicals was less, results showed.. The most consistent effects seemed to come from DDT and related pesticides, said study co-author Pauline Mendola, an investigator at the U.S. National Institute of Child Health and Human Development.. Bones seem to be more affected, she said. Head circumference and femur length were more often impacted than other growth measures.. This study looked at persistent organic pollutants -- chemicals once used in agriculture, pest control, manufacturing and industrial ...
MONDAY, Dec. 30, 2019 (HealthDay News) -- Decades-banned pesticides apparently continue to interfere with fetal growth during U.S. pregnancies, a new study reports.. DDT was banned in 1972 in the United States, but low levels of it and other organic chemical pollutants can still be found in the blood of pregnant American women, researchers reported online Dec. 30 in JAMA Pediatrics.. Women carrying even low levels of these pollutants had slightly smaller fetuses than women whose exposure to the chemicals was less, results showed.. The most consistent effects seemed to come from DDT and related pesticides, said study co-author Pauline Mendola, an investigator at the U.S. National Institute of Child Health and Human Development.. Bones seem to be more affected, she said. Head circumference and femur length were more often impacted than other growth measures.. This study looked at persistent organic pollutants -- chemicals once used in agriculture, pest control, manufacturing and industrial ...
NTP Experiment-Test: 96007-05 NEOPLASMS BY INDIVIDUAL ANIMAL Report: PEIRPT04 Study Type: CHRONIC TOXIC EQUIVALENCY FACTOR EVALUATION(PECDF) Date: 07/14/03 Route: GAVAGE Time: 14:46:46 31 WEEK SSAC RATS Facility: Battelle Columbus Laboratory Chemical CAS #: 57117-31-4 Lock Date: 07/25/02 Cage Range: All Reasons For Removal: 25017 Scheduled Sacrifice Removal Date Range: 11/03/99 - 11/04/99 Treatment Groups: Include All Note: Animals arranged according to CID number Page 1 NTP Experiment-Test: 96007-05 NEOPLASMS BY INDIVIDUAL ANIMAL Report: PEIRPT04 Study Type: CHRONIC TOXIC EQUIVALENCY FACTOR EVALUATION(PECDF) Date: 07/14/03 Route: GAVAGE Time: 14:46:46 __________________________________________________________________________________________________________________________________ , 2, 2, 2, 2, 2, 2, 2, 2, 2, 2, 2, 2, 2, 2, 2, 2, , , DAY ON TEST , 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, 1, , , , 2, 1, 1, 1, 1, 1, 2, 2, 2, 2, 1, 1, 1, 1, 1, 2, , , ...
Dioxin. Computer model of a molecule of the dioxin 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Atoms are represented as spheres and are colour-coded: carbon (lilac), chlorine (green), hydrogen (white) and oxygen (red). Dioxins are a family of toxic by-products of a number of industrial processes, including burning waste, heating metals and bleaching paper and textiles. They have no industrial use themselves. They are persistent organic pollutants (POPs) and build up over time in living tissue (bioaccumulation). Long-term high-level exposure can cause birth defects, cancer and a higher risk of diabetes. TCDD is one of the most toxic of the dioxins. - Stock Image A654/0038
Residents from a San Jacinto riverfront community stood together on Tuesday to express concern that one of the most polluted properties in Harris County could be breached by a storm, spreading dioxin contamination widely. Dioxins, which some health experts consider the most toxic compounds created by man, are heavily present in the sediments of the San Jacinto River near the community of Highlands, where two former paper plants dumped waste into pits. The location of these industrial dump sites had been forgotten for years until Texas parks and wildlife officers, looking for the source of dioxins in Galveston Bay, rediscovered the partially underwater pits in 2005. According to the Environmental Protection Agency, International Paper is the company responsible for the actions of Champion Paper, which generated the pulp-related waste. Waste Management was not affiliated with MIMC during that period, never operated MIMC, never owned the San Jacinto River Waste Site property and was never involved in
In response to the recent discovery of dangerous levels of dioxins in animal feed produced in Germany, Phenomenex has announced its publication of a method for analysing the chemicals using high-resolution gas chromatography with mass spectrometric detection.
Waters provides magnetic sector and APGC-MS/MS systems for the detection and quantification of dioxins and related compounds at ultra-trace levels.
Waters provides magnetic sector and APGC-MS/MS systems for the detection and quantification of dioxins and related compounds at ultra-trace levels.
After the Japan disaster, the workers undergoing the task of clearing millions of tonnes of debris face threats from asbestos and dioxins.
Get the latest dioxins removal (air and climate) news on Environmental XPRT, the worlds largest environmental industry marketplace and information resource.
There have been many studies about dioxin but there is a lot that we do not know about how dioxin affects people. For example, we do not know how much dioxin affects a person or how long a person has to be exposed for before they are affected. Animal studies show cancer, immune, reproductive, and developmental effects but the evidence of non-cancer effects in people is limited.. The most well studied dioxin is called 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). In animal research, dioxin seems to be a strong promoter (helps it along) and weak initiator (starter) for the development of cancer. This means that cancer development following dioxin exposure may depend on other causes of cancer like tobacco use.. The Institute of Medicine of the National Academy of Sciences in the United States of America regularly reviews the evidence about dioxin exposure and health. It makes a list of conditions that it accepts as being associated with dioxin exposure. It accepts the following conditions as being ...
The CYP1A1 and CYP1B1 genes are members of aromatic hydrocarbon receptor battery genes. The expression of these genes, therefore, is thought to be induced concomitantly through the activation of aromatic hydrocarbon receptor. In agreement with this concept, both CYP1A1 and CYP1B1 mRNAs were induced by the treatment of human blood monocytes with dioxins or PAHs in vitro (11 , 12) . The subjects whose leukocytes were analyzed in this study were workers occupationally exposed to dioxins at waste incinerators (9) . Thus, we expected that both CYP1A1 and CYP1B1 mRNAs might be induced by environmental exposure to dioxins. However, we found that the expression of only CYP1B1 mRNA was induced, whereas the expression of CYP1A1 mRNA was not induced. The reason accounting for the fact that only CYP1B1 mRNA was induced is not known at present.. After the first report on the significant association between AHH inducibility in human lymphocytes and the bronchogenic cancer risk (3) , many papers have appeared ...
One study conducted by the Environmental Protection Agency discovered that human fat cells contain dioxin and traces of four solvents. Whats more, 90 percent of them included three more dioxins, while 83 percent PCBs (industrial chemicals).. Dioxins are chemicals dangerous for your health, formed during combustion, as well as pulp bleaching and other industrial processes.. They can cause a wide range of health complications, so the body stores them in fat cells to prevent them from roaming free and causing organ damage. Bit, this leads to another serious problem.. The first thing to understand is that toxins can be fat-, or water-soluble. They include different pesticides, preservatives, food additives, plastics, pollutants, and heavy metals.. Now, the next thing is the function of bile. This liver fluid breaks down fat and removes old erythrocytes (red blood cells) from the body.. The gut is permeable during digestion, allowing the lymph to identify absorbed fat and take it to the liver for ...
In 1996, dioxins were discovered in ball clay as a result of an investigation to determine the sources of elevated dioxin levels in two chicken samples from a national survey of poultry. The investigation indicated that the contamination source was ball clay added to chicken meal as an anti-caking agent. The purpose of this study was to evaluate another potential exposure scenario associated with ball clay, namely its use in ceramic art studios. This exploratory investigation makes preliminary exposure estimates that can be used to evaluate whether more detailed follow-up analyses will be needed ...
Dioxins and PCBs can be carcinogenic at minimal here levels of exposure eventually. These substances are determined and measured in a single of two classes, dioxin-like PCBs and full PCBs. Even though the U.S. FDA has not established a limit for PCBs in supplements, the worldwide Business for EPA and DHA (GOED) has founded a guideline making it possible for for no more than three picograms of dioxin-like PCBs for each gram of fish oil ...
en] Among the different analytical tools proposed as an alternative to the very expensive gas chromatography high-resolution mass spectrometry (GC-HRMS) analyses of polychlorodibenzo-p-dioxin and polychlorodibenzofurans, Chemically Activated LUciferase gene eXpression (CALUX) in vitro cell bioassay is very promising. It allows the analyses of a high number of samples since it is relatively fast, inexpensive, and sensitive. However, this technique is not yet widely applied for screening or environmental monitoring. The main reasons are probably the lack of validation and the difficulty in interpreting the global biological response of the bioassay. In this paper, the strict quality control criteria set up for the validation of CALUX are described. The validation has shown good repeatability (relative standard deviation (RSD) = 9%) and good within-lab reproducibility (RSD = 15%) of the results. The quantification limit, in the conditions applied in this paper, is 1.25 pg CALUX-TEQ/g fat. ...
In the northwestern Icelandic town of Isafjordur, milk is causing pandemonium. A local milk marketing board recently tested one farms milk for the presence of harmful chemicals. Dioxin, and dioxin-like compounds, were found to be present in amounts higher than the recommended maximum levels, threatening the future of local farmers, and angering residents.
sam wrote: ---- Food for thought: PVC production has almost tripled in the last fifteen years. Yet, dioxin exposure has dropped by over 75% in the last decade; I am talking the total biologically available as a function of TEQ. Seems to me that if the PVC industry was the smoking The reports on dioxin exposure are independent university research efforts or government studies (US and Europe), *not* from the PVC industry. ---- aside from phillips response questioning the 75% drop in exposure; as to pvc sources contribution we need to look at a more complete picture than what gp has managed to extract from that industry. pcdd/f attributable to pvc come from the complete life cycle, not just the pcdd/f produced at the pvc & edc plants. and since pvc production skyrocketed only recently, how much of the increase has gone through its life cycle and been incinerated? also, a certain fraction of pcdd/f created at production will not contribute to exposure for a long time (ie that portion landfilled, as ...
Of course, paper has many uses. Its everywhere; books, newspapers, wallpaper, lampshades, cups, plates, paper bags, hats, insulation, filters, toilet paper, kites, playing cards, origami. It has been a transformative material.The downside is that paper production is a massive, global polluter on land, water and air. It is the third largest industrial, polluter in North America, the fifth biggest user of energy and uses more water per ton of product than any other industry.Paper in landfill sites accounts for around 35% of all waste by weight. Recycling helps but even the deinking process produces pollutants. Paper production still uses chlorine and chlorine based chemicals and dioxins are an almost inevitable part of the paper production process. Water pollution is perhaps the worst, as pulp mill waste water contains is oxygen hungry and contains an array of harmful chemicals and harmful gases and greenhouse gases are also emitted. It may seem as though reforestation is a plus, but these are ...
To celebrate our 25th anniversary, we are planning special deals and promotions throughout the year. We encourage you to stay informed by signing up for our newsletter. ...
Polychlorinated dioxins, dibenzofurans (PCDD/PCDF) and polychlorinated biphenyls (PCBs), are persistent organic pollutants (POPs) that bioaccumulate in lipids and may enter the food chain through animal products. Recently, Polish authorities discovered a free range farm whose eggs exceeded national standards for dioxin contamination two-fold. Piskorska-Pliszczynska et al.1 evaluated samples from that farm to determine the likely source of the dioxin exposure and to quantify the bioaccumulation of PCDD/Fs and PCBs in the tissues and eggs of the affected hens. They took specimens from the commercial feed and the soil of the free range areas. A veterinarian also performed necropsies and sampled muscle, abdominal fat, liver tissue, ovarian follicles, and whole eggs present in the oviducts. The researchers identified 35 PCDD/F and PCB congeners of interest, including dioxin-like polychlorinated biphenyls (DL-PCBs) and non-dioxin-like polychlorinated biphenyls (NDL-PCBs), using gas chromatography ...
Free Public Domain Picture: U.S. Ambassador David B. Shear speaks at the Environmental Remediation of Dioxin Contamination at Danang Airport Project Launch | ID: 13989043215339
Figure 6: Hypothetical diagrams of the effect of Bakumondo-to. (a) After ligation of dioxins to the AhR, the receptor translocates from the cytosol to the nucleus, binds to DRE, and activates transcription of CYP1A1, mucin and other genes in bronchiolar Clara cells. Excess mucin production from Clara cells by dioxins is supposed to be responsible at least in part for respiratory symptoms of Yusho patients. (b) Active ingredients in Bakumondo-to would block activation of the AhR by competitive interference with the interaction between dioxins and the AhR, and inhibit transcription of mucin in Clara cells, leading to improvement of respiratory symptoms of Yusho patients ...
Dioxins and dioxin-like chemicals are predominantly produced by thermal processes such as incineration and combustion at concentrations in the range of 10-100 ng of I-TEQ/kg (I-TEQ = international toxic equivalents). In this work, a new approach for the removal of dioxins from high-temperature vapor streams using facilitated supported ionic liquid membranes (SILMs) is proposed. The use of ceramic membranes containing specific ionic liquids, with extremely low volatility, for dioxin removal from incineration sources is proposed owing to their stability at very high temperatures. Supported liquid membranes were prepared by successfully immobilizing the ionic liquids tri-C₈-C₁₀-alkylmethylammonium dicyanamide ([Aliquat][DCA]) and 1-n-octyl-3-methylimidazolium dicyanamide ([Omim][DCA]) inside the porous structure of ceramic membranes. The porous inorganic membranes tested were made of titanium oxide (TiO₂), with a nominal pore size of 30 nm, and aluminum oxide (Al₂O₃), with a nominal ...
Persistent organic pollutants (POPs) are fat soluble chemical substances that persist in the environment and bioaccumulate in the food chain. Through long-range environmental transportation by air, water and migratory species they are transferred to new locations distant from the source of release and might cause adverse effects to human health and to the environment. POPs comprise pesticides, industrial chemicals and unwanted by-products. The European Commission has implemented food and feed legislations concerning maximum permitted levels (MPLs) of polychlorinated dibenzo-p-dioxins and furans (PCDD/Fs), dioxin-like polychlorinated biphenyls (DLPCBs), polycyclic aromatic hydrocarbons (PAHs) and organochlorine pesticides (OCPs). Fish and consequently fishmeal and fish oil has been identified as one of the most important contributors to the level of dioxins and DL-PCBs in food and feed products. Fish caught in some of the North-European fishing areas contain high dioxin and PCB levels resulting ...
Polychlorinated dibenzo-p-dioxins, dibenzofurans, and polychlorinated biphenyls are persistent environmental pollutants which ubiquitously occur as complex mixtures and accumulate in the food and feed chain due to their high lipophilic properties. Of the 419 possible congeners, only 29 share a common mechanism of action and cause similar effects, the so called dioxin-like compounds. Dioxin-like compounds evoke a broad spectrum of biochemical and toxic responses, i.e. enzyme induction, dermal toxicity, hepatotoxicity, immunotoxicity, carcinogenicity as well as adverse effects on reproduction, development, and the endocrine system in laboratory animals and in humans. Most, if not all, of the aforementioned responses, are mediated by the aryl hydrocarbon receptor. In the present work, the elicited biochemical effects of a selection of dioxin-like compounds and the non dioxin-like PCB 153 were examined in mouse (in vivo) and in human liver cell models (in vitro). Emphasis was given to the main ...
The United States Environmental Protection Agency (US EPA) has been in the process of conducting a reassessment of the health damaging effects of dioxin exposure for the past decade. In 2000, the agency published a draft risk characterization that attributed a 1 in 1000 upper-bound excess cancer risk to average background levels of dioxin exposure.. Several federal government agencies, including: the US Department of Agriculture, the US Food and Drug Administration, the US Department of Health and Human Services, and the EPA, are represented on the Interagency Working Group on Dioxin. These parties have developed a paper entitled Questions and Answers About Dioxins that provides basic information for the public on the matter of exposure and adverse health effects.. The Institute of Medicine (IoM) published, Dioxins and Dioxin-Like Compounds in the Food Supply: Strategies to Decrease Exposure , in 2003. The critical message of this report is that current levels of dioxins and dioxin-like ...
Boys had been recruited at age 8 or 9 years, and pubertal stage was assessed yearly based on testicular volume and genital maturity according to the Tanner Stages, a scale of physical development. Both the boys and their mothers provided blood samples for genetic and contaminant analyses at the study outset, and health, lifestyle, and diet data were collected through questionnaires.. Previous analyses had indicated that serum concentrations of dioxins and dioxin-like compounds were associated with later pubertal onset among these boys. The current study, conducted when the boys had reached age 12 or 13 years, investigated whether genetic variations modified this outcome.. The investigation included 392 boys and involved 337 SNPs identified in 46 genes and 2 intergenic regions (stretches of DNA between protein-coding genes) that may influence pubertal onset or the biological response to dioxins. The association of serum dioxins with later pubertal onset was confirmed, and two statistical methods ...
You probably havent heard anything about this group of toxic chemicals for almost six years. Formed during combustion processes such as waste incineration, theyre known to increase the likelihood of cancer after long-term low level exposure. At higher levels, dioxins can be disfiguring or deadly. It was six years ago that the world first saw a clear example of the damage that dioxins can cause. The face of former Ukrainian President Viktor Yushchenko was heavily scarred, the effect of a chloracne outbreak after suspected dioxin poisoning. He might have been poisoned with as little as a drop and significant amounts of poison could remain in his system for the rest of his life. Wikipedia paints a much scarier portrait of the 70+ isomers of highly toxic, man-made organic compounds. Byproducts of some industrial processes and waste incineration, dioxins are fat-soluble, so they tend to accumulate in the tissues of the animals who encounter them and it can take many years for the compounds to ...
Epidemiological studies suggest that exposure to persistent organic pollutants such as organochlorines might induce cardiovascular disorders and diabetes. Some of these organochlorines, such as dioxins and some dioxin-like PCBs, have been characterised as anti-estrogenic due to their inhibition of estrogenic-induced responses. In the present pilot study, 40 female rats were subjected to either exposure to the dioxin-like 3,3,4,4,5-pentachlorobiphenyl (PCB 126) or vehicle, as well as ovariectomy (OVX) or sham operation in a 2 x 2 factorial design over 12 weeks to explore potential interactions between estrogen status and PCB 126 exposure on cardiovascular risk factors. PCB 126 increased heart weight and serum cholesterol levels in both groups. PCB 126 increased blood pressure in the sham-operated animals only. In conclusion, PCB 126 exposure in female rats resulted in effects on cardiovascular risk factors, such as serum cholesterol, blood pressure, and heart weight. Of these effects of PCB ...
Johns Hopkins has recently sent this out in its newsletters. This information is being circulated at Walter Reed Army Medical Center as well. Dioxin chemicals causes cancer, especially breast cancer. Dioxins are highly poisonous to the cells of our bodies. Dont freeze your plastic bottles with water in them as this releases dioxins from the plastic. Recently, Dr. Edward Fujimoto, Wellness Program Manager at Castle Hospital , was on a TV program to explain this health hazard. He talked about dioxins and how bad they are for us.. He said that we should not be heating our food in the microwave using plastic containers. This especially applies to foods that contain fat. He said that the combination of fat, high heat, and plastics releases dioxin into the food and ultimately into the cells of the body. Instead, he recommends using glass, such as Corning Ware, Pyrex or ceramic containers for heating food. You get the same results, only without the dioxin. So such things as TV dinners, instant ramen ...
Toxic dioxins and furans can accumulate through industrial processes. SGS dioxin and furan analysis can accurately measure trace quantities to improve your site safety. Find out more.
So far we have looked at the disturbing unreliability of the existing pro-TDF studies, the special problems posed by burning tires in paper mill boilers, and the alarming lack of knowledge about a wide range of potential dangers that tire incineration may pose to the health and safety of our communities and the environment. This next section will take a closer look at the existing record and find that even based on the limited knowledge that exists, it is already clearly evident that tire incineration is dangerous.. Below is a breakdown of some of the condemning test data, organized by chemical groupings:. Dioxins and Furans. Dioxins are highly toxic and cause serious health problems, including infertility, learning disabilities, endometriosis, sexual reproductive disorders, birth defects, damage to the immune system and cancer. Dioxin is fat-soluble and once its released into the outside environment, it readily climbs up the food chain, causing average meat and dairy-product consumers to get ...
The Formosa Plastics Corporation plant is located near Illiopolis, between Springfield and Decatur along I-72. On April 23, 2004, an explosion occurred at the plant followed by a fire that burned for several days. Illinois EPA, along with other agencies, have worked to test air quality during and after the fire, water quality in creeks and streams near the site and the safety of the drinking water supply. Illinois EPA will continue to have a long-term presence at the site in the form of oversight regarding site investigation and proper cleanup of contamination.. Dioxins and other chlorinated chemicals may have been formed during the smoldering phases of the fire at the plant. A few initial samples were taken to test for dioxins on the site. In addition, initial sampling of 13 public and private properties was performed on June 30, 2004 by Formosa, with oversight by Illinois EPA. The results of those screening samples showed the presence of low levels of dioxins. Illinois EPA requested that ...
INTERNATIONAL. IARC releases monograph on benzene. OECD…. …Draft test guidelines. …Risks of mixed exposures. …Validation studies of two in vitro test methods (skin corrosion and eye irritation). …Updated reporting templates. JECFA reports on food contaminants. WHO Expert Committee on Drug Dependence reviews a range of drugs including cannabis. EUROPE. REACH…. …Member State Committee (MSC) deliberations on substances of very high concern (SVHCs). …Draft recommendation for authorisation list. …Testing proposals involving vertebrate animals. …ECHA to derive occupational exposure limits. Classification and labelling…. …Proposal for harmonised classification and labelling. …RAC opinions on harmonised classification and labelling. Biocidal Products Regulation. …BPC opinions on seven active substances. EFSA…. …Evaluation of propylene glycol esters of fatty acids as a food additive. …Consideration of dioxins and dioxin-like polychlorinated biphenyls. …Assessment of ...
July 25, 2014. By Marie Zhuikov. Researchers already know that dioxin (a byproduct of burned plastics and industrial processes) is toxic and can contribute to cancer and heart problems in humans, but now they know it can impact a fishs nose tissue. Why should we care? Because fish use their noses to navigate through water and to find streams for spawning.. Wisconsin Sea Grant-funded researcher, Michael Carvan, Shaw associate scientist at the University of Wisconsin-Milwaukee School of Freshwater Sciences, has been studying the impacts of dioxin on rainbow trout (Oncorhynchus mykiss) and zebrafish (Danio rerio). Although zebrafish are not a Great Lakes species like the trout, researchers use them because they are a hardy lab fish about which much is known.. Carvan and his research team fed both young rainbow trout and zebrafish food containing different levels of TCDD (tetrachlorodibenzo-p-dioxin) over a six-week period. They chose to work on juvenile fish because few studies for dioxin exposure ...
in Accreditation and Quality Assurance (2006), 11(1-2), 38-43. In the determination of contaminants (dioxins, polychlorinated biphenyls, polyaromatic hydrocarbons), cell-based assays are useful methods for screening purposes: they are mainly characterized by high ... [more ▼]. In the determination of contaminants (dioxins, polychlorinated biphenyls, polyaromatic hydrocarbons), cell-based assays are useful methods for screening purposes: they are mainly characterized by high sample throughput and lower costs than the Mass Spectrometry (MS)-based methods. Although cell-based assays can be sensitive enough for the determination of dioxins and related substances in agreement with the presently tolerable limits in food and feed (Regulation No. 2375/2001/EC and Directive 2003/57/EC respectively), their lack of specificity make their use rather questionable in control laboratories. In this paper, we present and compare results obtained from the analysis of a limited number of feed samples by both gas ...
The Department continued to work in the Urban Rivers Team. The team focuses on the Woonasquatucket River until priority issues such as dioxins are controlled.. The Woonasquatucket River watershed encompasses most of the Town of Smithfield as well as parts of North Smithfield, Glocester, Johnston, and Providence. The 18 mile river arises in a rural area, flows into increasingly urbanized territory and ends at Waterplace Park in Providence. The River suffers from the cumulative impacts of industrial contaminants such as dioxins and PCBs in urban stretches. Other problems include excess nutrient loading, abandoned industrial sites, litter and illegal dumping of solid waste. While some stretches of the urban river bank are surprisingly healthy, others are degraded and provide poor habitat.. In 1999, the Department began work with the American Heritage River Steering Committee, the Urban Rivers Team, and the USEPA River Navigator to coordinate watershed efforts and to produce a State of the Watershed ...
PVC produces HCl upon combustion almost quantitatively related to its chlorine content. Extensive studies in Europe indicate that the chlorine found in emitted dioxins is not derived from HCl in the flue gases. Instead, most dioxins arise in the condensed solid phase by the reaction of inorganic chlorides with graphitic structures in char-containing ash particles. Copper acts as a catalyst for these reactions.[54]. Studies of household waste burning indicate consistent increases in dioxin generation with increasing PVC concentrations.[55] According to the EPA dioxin inventory, landfill fires are likely to represent an even larger source of dioxin to the environment. A survey of international studies consistently identifies high dioxin concentrations in areas affected by open waste burning and a study that looked at the homologue pattern found the sample with the highest dioxin concentration was typical for the pyrolysis of PVC. Other EU studies indicate that PVC likely accounts for the ...
PVC produces HCl upon combustion almost quantitatively related to its chlorine content. Extensive studies in Europe indicate that the chlorine found in emitted dioxins is not derived from HCl in the flue gases. Instead, most dioxins arise in the condensed solid phase by the reaction of inorganic chlorides with graphitic structures in char-containing ash particles. Copper acts as a catalyst for these reactions.[55] Studies of household waste burning indicate consistent increases in dioxin generation with increasing PVC concentrations.[56] According to the EPA dioxin inventory, landfill fires are likely to represent an even larger source of dioxin to the environment. A survey of international studies consistently identifies high dioxin concentrations in areas affected by open waste burning and a study that looked at the homologue pattern found the sample with the highest dioxin concentration was typical for the pyrolysis of PVC. Other EU studies indicate that PVC likely accounts for the ...
For those of you w/ WWW access, check it out at http://www.epa.gov/OST/fishadvice/facts.html Heres teh text (w/out the cool maps) The Alliance for Environmental Technology is, of course, highlighting this part: ...The total number of advisories for dioxins was 54 in 1993, then rose to 63 in 1994, held steady at 63 in 1995, and declined to 60 advisories in 1996. Dioxins are one of several chemical contaminants for which advisories have been rescinded by some states, in part because many pulp and paper mills have changed their processes. ... Note that we in MN lead the U.S, pack w/ 709 -- 693 due to mercury! ================ United States Environmental Protection Office of Water EPA-823-97-007 Agency Mail Code 4305 June 1997 ---------------------------------------------------------------------------- [Image] Fact Sheet Update: Listing of Fish and Wildlife Advisories Summary The 1996 update for the database, Listing of Fish and Wildlife Advisories (LFWA), is now available from the U.S. ...
Summary/Abstract The aryl hydrocarbon receptor (AhR) is known for mediating the toxicity of environmental pollutants such as dioxins and numerous dioxin-like compounds. Due to the widespread occurrence in our environment and the high toxic potential, these contaminants are of concern to promote malignancies including breast cancer. More recently it has been found that the AhR may also act as a critical receptor protein in tumor promotion independent from exogenous ligands, which is based on immune tolerance and increased survival in cancer cells. Consequently, the AhR has emerged as an attractive target for new drugs in cancer therapy. Furthermore, the AhRs action is restricted by a specific repressor protein, the AhR Repressor (AhRR). The AhRR is a ligand-independent, transcriptionally inactive AhR-like protein and is thought to repress AhR signaling. While AhRR effectively blocks AhR, the role of AhRR as a tumor suppressor gene is only poorly understood. We established a transgenic mouse ...
Dioxins are found in meat, poultry, fish and even in milk. In just six months of breast feeding, a baby in the U.S. will, on average, consume the EPAs maximum lifetime dose of dioxin.1 these toxins get passed on to humans from the plants animals eat. They are stored in the fatty tissues and then we n turn eat it. Then it stores in our fat, and creates a build-up.. Of course we are all digesting these poisons, but if you look through the Canadian Cancer Statistics for 2011, featuring a study on Colorectal Cancer, produced by the Canadian Cancer Society, it says, The estimated incidence rates for all cancers combined continue to be highest for the maritime provinces and Quebec and lowest in British Columbia.2 Its easy enough to why this is, when you take the north-west prevailing winds into consideration. Based on current incidence rates, 40% of women and 45% of men in Canada will develop cancer during their lifetimes. But this expectancy increases the farther east you live.. Watch this ...
Svante Arrhenius väg 8, Stockholm. Arrheniuslaboratoriet, Svante Arrhenius väg 16, Stockholm (Unit for Analytical and Toxicological Chemistry). Mailing address: ...
The fact that the molecular mechanisms of dioxin toxicity are still poorly understood complicates dioxin risk assessment. Only one mechanism of dioxin action, the direct induction of CYP1A1, has been elucidated in detail (5). However, despite its direct regulation by the AHR, CYP1A1 induction is not predictive of dioxin toxicity.. A useful tool for studying the mechanisms of dioxin toxicity is the large sensitivity difference in TCDD-induced lethality between H/W and L-E rat strains. Although there is a large sensitivity difference in certain endpoints of TCDD toxicity (e.g. acute lethality, wasting, and hepatotoxicity), other responses, such as induction of CYP1A1, remain similar between these strains (3). A wide range of clinical chemistry variables and biochemical parameters have been investigated in an effort to rationalize the differences between these two strains, but no clear molecular factors responsible for TCDD resistance in the H/W rat strain have been identified.. The aim of this ...
Postdoctoral Training, Harvard Medical School. BUMC Research Profile. Recent studies have demonstrated that a number of common environmental pollutants (i.e. aromatic hydrocarbons, dioxins, PCBs) compromise the immune system as well as induce cancer. Like immunosuppressive therapeutics (e.g. steroids), these compounds induce thymic atrophy, decrease resistance to infectious agents and transplantable tumors, reduce bone marrow cellularity, alter lymphocyte homing, impair B cell antibody responses, decrease cytotoxic T cell activity, inhibit natural killer activity and decrease cytokine production. Immunotoxicity mediated by extremely low concentrations of environmental pollutants is regulated by an intracellular aromatic hydrocarbon receptor (AhR) which, when bound by hydrocarbons, dioxins, or PCBs, translocates to the nucleus, activates gene promoters, and induces transcription of a number of genes including proto-oncogenes and cytokine genes. Although the endogenous AhR ligand is unknown, work ...
Adhere to stringent environmental regulation with our comprehensive range of reference materials for dioxin & furan testing. 500+ products available online.
Fish with the high levels of dioxins are Baltic herring, Baltic salmon and Baltic sprats.. Under EC regulations that came into force on January 1 last year, the area in which fish are caught must now be specified.. Sweden and Finland have undertaken not to sell their fish to other European countries and, where they are still selling their fish domestically, health authorities must issue warnings to women of child-bearing age against regularly eating Baltic salmon or herring. Other consumers are being warned not to eat oily fish from the Baltic more than once a week. ...
One long-running battle centers on Mossville, a small African-American community founded in the 1790s across from Lake Charles, La.. Fourteen major industrial facilities surround the community, including an oil refinery, a coal plant, chemical manufacturers and one of the largest clusters of vinyl production facilities in the United States.. For 15 years, residents have been asking government and industry to relocate them from the powerful odors and toxic chemicals released by the plants, citing reports showing dangerous levels of dioxins in the air. Dioxins, researchers say, can cause cancer and reproductive damage and slow child development.. In 1998, the federal Agency for Toxic Substances and Disease Registry found that Mossville residents had an average dioxin blood level three times above that in the typical U.S. community.. The report, however, did not identify the source of the exposure. A later ATSDR report said residents in the neighboring parishes of Calcasieu and Lafayette had ...
More and more people are aware that eating certain types of seafood can increase your exposure to mercury, PCBs, dioxins and pesticides. Industrial activities have significantly elevated the amount of mercury and other toxics chemicals in the environment. Present in the air and water, these contaminants have made their way into some of the food we eat.. Mercury in fresh and marine waters is converted by bacteria into methylmercury, which is easily absorbed by animals as they feed and binds to fish protein. Methylmercury and persistent organic compounds, such as dioxins and PCBs, accumulate in fish tissue and become concentrated in fish high on the food chain. Residues of antibiotics and hormones used in aquaculture may be a cause for additional caution. However, there are still many seafood options that allow people to get the benefits of seafood without the risk of contaminants.. Health Canada, the U.S. Food and Drug Administration and the U.S. Environmental Protection Agency all issue warnings ...
Exposure to chlorinated dibenzo-p-dioxins (CDDs) (75 chemicals) occurs mainly from eating food that contains the chemicals. One chemical in this group, 2,3,7,8-tetrachlorodibenzo-p-dioxin or 2,3,7,8-TCDD, has been shown to be very toxic in animal studies. It causes effects on the skin and may cause cancer in people. This chemical has been found in at least 91 of 1,467 National Priorities List sites identified by the Environmental Protection Agency (EPA).
BKH/European Commission. Towards the establishment of a priority list of substances for further evaluation of their role in endocrine disruption: - preparation of a candidate list of substances as a basis for priority setting. Final report-November 2000. http://europa.eu.int/comm/environment/docum/01262_en.htm#bkh. Category 1 chemicals from Annex 1: Candidate list of 553 substances. http://europa.eu.int/comm/environment/docum/bkh_annex_01.pdf, Brucker-Davis, F. Effects of Environmental Synthetic Chemicals on Thyroid Function. Thyroid. 8(9): 827-856. 1998., Illinois EPA. Endocrine Disruptors Strategy. 1997. (Table 1: Preliminary List of Chemicals Associated with Endocrine System Effects in Animals and Humans or In Vitro). http://www.nihs.go.jp/hse/environ/illiepatable.htm, Japanese National Institute of Health Sciences. Lists of Paradigmatic Chemicals. http://www.nihs.go.jp/hse/endocrine-e/paradigm/paradigm.html, Keith, L.H. (ed.). Environmental Endocrine Disruptors. John Wiley & Sons, NY. 1997. ...
PVC is everywhere - in our houses, in our childrens toys, in the air and most concerning- in our food. Low exposures to dioxins from the manufacture and disposal of PVC cause mutations thus tumors in our bodies. Any molecule that is present in our bodies poses a risk of cancer. As a doctor from Columbia University said on the film: Zero exposure is best. Dioxins affect EVERYONE - not only those who live near the factories that create PVC (i.e. Lake Charles, Louisiana and Venice, Italy). PVC is the worst plastic from an environmental health perspective, posing great environmental and health hazards in its manufacture, product life and disposal. - MyHouseIsYourHouse.org (My House is Your House is the consumer education and advocacy campaign tied to Blue Vinyl.) ...
The Finest Organic, Vegan and Natural Beauty Brands, The Middle Easts First Online Store for Organic and Natural Health and Beauty Products
The objective of this research project is to determine whether exposure to dioxins, a byproduct of industrial processes and an environmental contaminant, is associated with altered growth and sexual maturation in boys. Specific objectives include exploring whether physical growth is delayed and stunted, whether sexual maturation is delayed, and whether reproductive hormones are altered. Dioxin levels will be measured in blood samples drawn from the boys and their mothers. Yearly physical examinations will be performed to assess growth velocity and onset and tempo of sexual maturation. Questionnaire data will be collected on birth and medical history, as well as lifestyle factors. Statistical modeling will be used to explore the relationship between serum levels of dioxin and altered physical growth and sexual maturation.. ...
This video is an introduction to the United Nations Environment Programmes Dioxin Toolkit (2013). It offers a brief history of the Toolkit, including its relationship to the Stockholm Convention, and a step-by-step search of the Toolkit for information on identifying sources of dioxins and other unintentional POPs addressed by the Convention.. The presenter in the video is Pat Costner, B.S., M.S., who worked with IPEN primarily via IPENs Dioxin, Waste and PCBs Working Group. Ms. Costner was a member of the Stockholm Conventions Toolkit Expert Group, a Senior Scientist with Greenpeace, and a Science Advisor for the Global Alliance for Incinerator Alternatives (GAIA).. ...
柴油車排氣中戴奧辛控制技術與焚化爐產生戴奧辛的人體暴露之研究. Treatment Effectiveness of Dioxin Emission from Diesel Engine and Human Exposure from Exhaust of Incinerator. ...
The European Food Safety Authority has published a new report on levels of dioxins and polychlorinated biphenyls (PCBs) in food and feed. Canada Environment Siskinds LLP 16 Aug 2012
In 2012, the Texas Department of State Health Services delivered its public health assessment of dioxin in the waste pits. The report again warned of hazards posed to fish, but it dismissed the idea of contamination in neighborhoods soil or well water.. Rifai said UHs studies of river water and sediment could not be used to determine whether yards, parks or well water was safe. She is now working with the Galveston Bay Foundation, an independent nonprofit, and Harris County to conduct more testing after Harveys flooding.. The Matulas have two wells on the cottage property. For decades, they drank from the older, shallow well. About 10 years ago, they dug a deeper one.. After Sean Matula paid for testing, he asked state health officials to review the complex lab reports. They found dioxin in the older well to be more than twice what the EPA considers dangerous for humans of any age to drink. Dioxin levels in the newer well represented an increased risk of cancer for children and adults but ...
Aryl Hydrocarbon Receptor, Human, Health, Hormone, Luciferase, Estrogen, Humans, Phytoestrogens, Environment, Food, Inuit, Transactivation, Cell, Cells, Gene, Reporter Gene, Concentration, Bioassay, Dioxins, Pesticides
Quantification of PCDD/Fs and dioxin-like PCBs in small amounts of human serum using the sensitive H1L7.5c1 mouse hepatoma cell line: Optimization and analysis of human serum samples from adolescents of the Flemish human biomonitoring program FLEHS IICROESA, K; VAN LANGENHOVE, K; VAN LAREBEKE, N et al.Talanta (Oxford). 2011, Vol 85, Num 5, pp 2484-2491, issn 0039-9140, 8 p.Article ...
Midland shortstop Jayson Nix -- before surrendering an RBI single to James Smith. A sacrifice fly and a run-scoring single later, Midland was up 3-0 with Hurley needing a sparkling defensive play by shortstop Ryan Hamilton to limit the damage. After a 10-minute delay, the Bearkats knotted the contest on Hurleys two-run single, scoring Dan Krenz and Joshua Barfield, and a sacrifice fly by Jake Oprea. Brad Cherrys two-out single to right drove in Jake Ashmore in the fifth to give the Bearkats a 4-3 edge, but Midlands bats would resurface in the bottom of the inning. Bose and Midland catcher Madison Edwards smacked consecutive run-scoring singles to push the Bulldogs back in front before Hurley allowed a walk and a three-run homer to Daniel Stovall, giving Midland an 8-4 advantage.
After nearly 30 years of delays caused by pressure from chemicals and defense industries, the US Environmental Protection Agency (EPA) is moving forward on setting a safety limit for exposure to dioxin, a ubiquitous, highly toxic and carcinogenic chemical that people of all ages ingest daily with their food - starting at a mothers breast.. The Environmental Working Group applauds the EPA for taking significant steps to set a long-overdue exposure limit for dioxin, a byproduct of combustion and various industrial processes that is found everywhere in the environment and in peoples bodies. EWG researchers say, however, that the allowable exposure levels may well need to be tightened in the future because of growing evidence that dioxin is even more dangerous than scientists had thought.. Nine animal studies conducted between 1973 and 2008 show that dioxin is harmful at levels even lower than in the human studies on which EPA based its proposal. Those human studies, conducted in 2008, explored ...
The main focus is on animal studies as the developmental basis of disease paradigm is particularly difficult to assess in humans at this point in time; as in utero exposures must be linked to gene expression or other tissue potential changes at birth and then linked to an adult disease. Nonetheless, humans are exposed to a variety of environmental chemicals in utero, many are the same chemicals that have been shown to cause increased incidences of disease/dysfunction later in life in animal studies and at similar concentrations to those used in the animal studies [7], [8] and [9]. Indeed a recent publication by The Environmental Working Group [10] showed that a variety of industrial chemicals, pollutants, and pesticides could be measured in human umbilical cord blood. They tested newborns for 413 environmental chemicals and found that 287 of them were found at some levels including various PCBs, mercury, DDT and dioxins. In addition, the Centers for Disease Control and Prevention (CDC), has ...