The absolute accuracy of measured order parameters is largely affected by the accuracy of the prefactor connecting the measured splittings to the order parameters (Eqs. (1) and (2)). When considering the change of an order parameter with a changing external condition (hydration, ion concentration, etc.), the prefactor can be considered to be unchanging. Therefore, the change in a given order parameter, when measured by the same people with the same technique and equipment, can be determined in a much higher accuracy than the absolute value of the order parameter. We refer to this as the relative accuracy. It is determined by the accuracy of the splitting measurement. Especially the very high spectral resolution of the ²H-measurements allows the measurement of very small order parameter changes. Let us exemplify this with a classical experiment by Akutsu et al., where the effect of different ions on the headgroup \(\alpha\)- and \(\beta\)-quadrupolar splittings was measured, see Fig. 1 ...
in Journal of Protein Chemistry (1994), 13(1), 77-88. Peptides corresponding to lipid binding domains of Apo B-100 were synthesized, purified, and incubated with dimyristoylphosphatidylcholine (DMPC) liposomes. The secondary structure of the apo B-100 ... [more ▼]. Peptides corresponding to lipid binding domains of Apo B-100 were synthesized, purified, and incubated with dimyristoylphosphatidylcholine (DMPC) liposomes. The secondary structure of the apo B-100 peptide-lipid complexes was evaluated by attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR). Those peptides belonging to the hydrophobic core domain of apo B-100 when associated with phospholipids were rich in beta sheet structure; a predominant alpha helical conformation was shown to be associated with one peptide located in a surface region of apo B-100. IR dichroic spectra revealed, in the case of the core peptides, that the beta sheet component is the only oriented structure with respect to the ...
[140 Pages Report] Check for Discount on Global and Chinese 1,2-dimyristoyl-sn-glycero-3-phospho-ethanolamine (CAS 998-07-2) Industry, 2017 Market Research Report report by Prof Research. The Global and Chinese 1,2-dimyristoyl-sn-glycero-3-...
en] The structure, composition, and physico-chemical properties of lipid-protein complexes generated between dimyristoylphosphatidylcholine (DPMC) and the CNBr fragments of human apoA-I were studied. The fragments were separated by high performance liquid chromatography and purified on a reversed-phase column. The complexes with DMPC were isolated on a Superose column; their dimensions were obtained by gradient gel electrophoresis and by electron microscopy. The secondary structure of the protein in the complexes was studied both by circular dichroism and by attenuated total reflection infrared spectroscopy. The fragments 1 and 4 of apoA-I, containing, respectively, two and three amphipathic helices, recombined with the phospholipid to generate discoidal particles with sizes similar to that of apoA-I- and apoA-II-DMPC complexes. The infrared measurements indicated that in all complexes the apolipoprotein helical segments were oriented parallel to the phospholipid acyl chains and that the protein ...
Page contains details about PLGA nanocapsules coated with phosphatidylcholine bilayer . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com
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Ras proteins regulate signal transduction processes that control cell growth and proliferation. Their disregulation is a common cause of human tumors. Atomic level structural and dynamical information in a membrane environment is crucial for understanding signaling specificity among Ras isoforms and for the design of selective anti-cancer agents. Here, the structure of the full-length H-Ras protein in complex with a 1,2-dimyristoylglycero-3-phosphocholine (DMPC) bilayer obtained from modeling and all-atom explicit solvent molecular dynamics simulations, as well as experimental validation of the main results, are presented. We find that, in addition to the lipid anchor, H-Ras membrane binding involves direct interaction of residues in the catalytic domain with DMPC phosphates. Two modes of binding (possibly modulated by GTP/GDP exchange) differing in the orientation and bilayer contact of the soluble domain as well as in the participation of the flexible linker in membrane binding are proposed. ...
back view slow motion http://youtu.be/PQHdIpTE2LQ back view normal speed http://youtu.be/8UG8g4jz6qs left view slow motion...
filmed inside a nightclub with real girls. The camera points straight up this girls skirt for a great upskirt video and the best bits are rewind and played back in slow motion.
Physically--Im so sore, and I become really achy super easily without doing much. Its very annoying. There are a few other symptoms as well that well keep discreet for now. Its beginning to get in the way of general daily things, so adjustments are being made. This was not at all the case with Braska. Its weird and frustrating, to be honest, but as long as Kinlees ok through it all, well deal. M carries her for me whenever possible, and I just have to plan time on my feet in small doses. I thought it might be related to some projects from a couple weeks ago, but its hung around too long to be due to that. Well see if the OB has any thoughts tomorrow. Im not really worried, but I would like to feel better for the next few months ...
How we perceive and manage stress is important to our overall health. When stress becomes too great, the damage may be irreversible.
55 matching references were found. Zhang C.; Zhang H.; Wang L.; Gao H.; Guo X.N.; Yao H.Y., Improvement of texture properties and flavor of frozen dough by carrot (Daucus carota) antifreeze protein supplementation, J. Agric. Food Chem., 2007, 55, 23, 9620-9626, https://doi.org/10.1021/jf0717034 . [all data] Johnston, H.S.; Paige, M.; Yao, F., Oxygen absorption cross sections in the Herzberg continuum and between 206 and 327 K, J. Geophys. Res., 1984, 89, 11661-11665. [all data] Yao, F.; Liu, W.; Qiu, Q., GC-MS Analysis of volatile oil from Atractylodes chinensis, Zhongyao Cai., 2001, 24, 9, 643-645. [all data] Nagano, H.; Yao, H.; Ema, K., Dynamic heat capacity at the gel to liquid-crystalline phase transition in large unilamellar vesicles of dimyristoylphosphatidylcholine in the ultralow frequency region, Phys. Rev. E: Stat. Phys., Plasmas, Fluids, Relat. Interd- iscip. Top., 1995, 51, 3363-7. [all data] Hatta, I.; Yao, H.; Kato, R.; Maesono, A., Development of ac calorimetric method for ...
Slow Motion Grimentz 2013 LEquipe CAP - Vidéo tournée lors du camp dété de Grimentz 2013 organisé par lEquipe CAP : Camp Animation Partage. Cette vidéo retrace bien lactivité au cours des camps : montagne magnifique, sport, ambiance, délires etc... 80 campeurs ont trouvés cles idées pour ...
Orientational order and vesicle shape. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
Two methods of measuring the misorientation of domains in oriented multilamellar stacks of lipid bilayers superficially appeared to give different values for the mosaic spread. It is first shown that the traditional rocking method and a newer ring method give the same value of the mosaic spread when the two
As a mother of a child diagnosed with this condition it is my responsibility to slowly build Nicks sensory endurance. Introducing events and new experiences slowly, building each time in intensity so that he can finally begin to function and relate better to our fast-moving world. This is a necessity if he is ever going to be able to live on his own, go to school or secure a job ...
Recently Mom took a spill in front of her house and I watched her go down -almost in slow motion. I was at least 15 feet away from her, so it wasnt possible to run to catch her somehow, but just watching her fall like that was VERY disturbing to me. Okay, now Im pregnant, so everything is a BIGGER deal than it might have actually been, but it was absolutely terrifying. I had the quick vision of mom going down and not coming back up. The fall was quite bad, and Mom was really banged up -her eyes were so bad, she couldnt tell if the huge cut on her arm was deep enough to go to the ER… It was the next day they found this tumor ...
Recently Mom took a spill in front of her house and I watched her go down -almost in slow motion. I was at least 15 feet away from her, so it wasnt possible to run to catch her somehow, but just watching her fall like that was VERY disturbing to me. Okay, now Im pregnant, so everything is a BIGGER deal than it might have actually been, but it was absolutely terrifying. I had the quick vision of mom going down and not coming back up. The fall was quite bad, and Mom was really banged up -her eyes were so bad, she couldnt tell if the huge cut on her arm was deep enough to go to the ER… It was the next day they found this tumor ...
WK 2,5 - 3 D SL. 56.503.8355.0. 50. WK 2,5 - 3 D SL-NGN. 56.503.8455.0. 50. WK 2,5 - 3 D SL-PGN. 56.503.8555.0. 50. 6 mm / 79 mm / 69 mm. 7 mm. E M D .. ...
Deuterium nuclear magnetic resonance (2H-NMR) was used to investigate the structure and dynamics of the sn-2 hydrocarbon chain of semi-synthetical choline and ethanolamine plasmalogen in bilayers containing 0, 30, and 50 mol% cholesterol. The deuterium NMR spectra of the choline plasmalogen yielded well-resolved quadrupolar splittings which could be assigned to the corresponding hydrocarbon chain deuterons. The sn-2 acyl chain was found to adopt a similar conformation as observed in the corresponding diacyl phospholipid, however, the flexibility at the level of the C-2 methylene segment of the plasmalogen was increased. Deuterium NMR spectra of bilayers composed of the ethanolamine plasmalogen yielded quadrupolar splittings of the C-2 segment much larger than those of the corresponding diacyl lipids, suggesting that the sn-2 chain is oriented perpendicular to the membrane surface at all segments. Cholesterol increased the ordering of the choline plasmalogen acyl chain to the same extent as in ...
A pulsed EPR saturation-recovery method has been used to measure spin-lattice relaxation times (T 1 ) for aminoxyl spin labels in cardiolipin bilayers, with and without cytochrome c. The relaxation time for each spin label was determined at various positions in the bilayer, which included the bilayer surface and three positions within the hydrophobia interior in the membrane, as well as a position close to the glycerol backbone of phospholipids in the bilayer. A dynamic profile for the hydrocarbon chains in bilayers was found in agreement with results from other techniques. On addition of cytochrome c to cardiolipin bilayers, changes in the spin-lattice relaxation time and order parameter were observed around the unsaturated region in the cardiolipin acyl chains. Supported by complementary lineshape analysis, these effects were interpreted as changes in the molecular dynamics around the double bonds in the acyl chains of cardiolipin bilayers, induced upon the binding of
The results of a computer program written to study rotational dynamics by following the reorientation of a carbon-deuterium (C-D) bond vector in a deuteriated molecule are described. Three-dimensional plots are constructed to show how deuterium nuclear magnetic resonance splittings vary as a function of two rotational parameters. It is suggested that these diagrams provide insight into the rotational motions of the molecule. © 1987 American Chemical Society.
We investigated the partitioning behavior of gramicidin A′ in various binary phospholipid mixtures in which gel and liquid crystalline phase coexistence had been induced. The quenching of the...
Page contains details about streptavidin-modified DNA T pores incorporated into biotinylated PC small unilamellar vesicles . It has composition images, properties, Characterization methods, synthesis, applications and reference articles : nano.nature.com
Its bath time for these cute pups....in super slow motion. Subscribe to The Pet Collective: http://full.sc/HbM62v Facebook: http://www.facebook.com/thepetco...
Download this Businesswoman Jumping In Air Doing Splits Slow Motion video now. And search more of the webs best library of royalty-free stock video footage from iStock.
Finally a program that really works capturing/recording video on my pc. BUT , whatever I do,the video are in `slow motion`.. why? why? why?...I cant figure this out...I've been using hours and...
Director Bob Purman used a Phantom camera at 1,000 fps to capture these expressive canines in action for a dog food commercial. The director was initially charged with shooting two spots, a Catch and a Jump execution. The director says: The Catch spot was to be a series of shots of dogs looking with anticipation as a piece of dog food is flying through the air towards them. The above video may play off the video below of dogs in slow motion: Via Creativity Online
Well, we dun dun it - fired a tracer round into ballistic gelatin and captured it in slow motion video for the world to see. We fired 18 of the 20 rounds in the box (commercially-available repacked M856) to check for trace function and all rounds lit up brightly and quickly out of the muzzle.…
Download this Hd Slow Motion Mountain Stream Crashing Against The Rocks video now. And search more of the webs best library of royalty-free stock video footage from iStock.
In Dr. Pimple Poppers new Instagram video, she extracts an arm cyst with her punch biopsy tool. Then, she squeezes it all out in super slow motion.
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Recently, there has been a surge of interest in mesogens exhibiting the twist-bend nematic (N-TB) phase that is shown to be chiral even though formed by effectively achiral molecules. Although it now seems to be clear that the N-TB phase in the bulk is formed by degenerate domains having opposite handedness, the presence of a supramolecular heliconical structure proposed in the Dozov model has been contradicted by the Hoffmann et al. model in which the heliconical arrangement is replaced by a polar nematic phase. The evidence in support of this is that the quadrupolar splitting tensor measured in various experiments is uniaxial and not biaxial as expected for the twist-bend nematic structure. In this debate, among other evidence, the molecular translational diffusion, and its magnitude with respect to that in the nematic phase above the N-TB phase, has also been invoked to eliminate or to confirm one model or the other. We attempt to resolve this issue by reporting the first measurements of the ...
This page includes the following topics and synonyms: E/M Nature of Presenting Problem, E/M Minimal Problem, E/M Self Limited or Minor Problem, E/M Low Severity Problem, E/M Moderate Severity Problem, E/M High Severity Problem.
This figure shows that no potential difference can be established across a pure lipid bilayer that separates solutions containing different ionic concentrations.
The invention relates to liquid-crystalline compounds of the formula I ##STR1##in which R.sup.1, R.sup.2, A.sup.1, A.sup.2, A.sup.3, A.sup.4, Z.sup.1, Z.sup.2, a, b and c are as defined in claim 1, and to liquid-crystalline media comprising at least compound of the formula I and to electro-optical displays containing a liquid-crystalline medium of this type.
Many of the diseases we associate with ageing - such as heart disease, cancer, dementia and stroke - may be the result of lifelong, poorly managed stress.
Read the tci E/M Coding Alert newsletter article titled: Reader Question: Think Before Coding E/M with Every Surgery - subscription required
Hi, I have a coarse-grained trajectory of a transmembrane protein with 5 TM helices and I would like to calculate the tilt angle of the protein over time and compare it with some published data. In the publication, the tilt angle was calculated between the membrane normal (Z axis) and protein axis ...
I have providers that do there out coding but what I am looking to find out is: A patient is having blood work the dx. code needs to be matched with t
The autoinhibition/activation of the PMCA (plasma membrane Ca2+-ATPase) involves conformational changes in the membrane region of the protein that affect the amount of lipids directly associated with the transmembrane domain. The lipid-protein-dependence of PMCA isoforms 2 and 4 expressed and obtained in purified form from Saccharomyces cerevisiae was investigated using the phosphatidylcholine analogue [125I]TID-PC/16 {l-O-hexadecanoyl-2-O-[9-[[[2-[125I]iodo-4-(trifluoromemyl-3H-diazirin-3-yl)benzyl]oxy]carbonyl]nonanoyl]-sn-glycero-3-phosphocholine}, which was incorporated into mixtures of dimyristoylphosphatidylcholine and the non-ionic detergent C12E10 [deca(ethylene glycol) dodecyl ether]. We found no differences between the recombinant PMCA4 and PMCA purified from erythrocytes (ePMCA). However, titration of the half-maximal activation by Ca2+/calmodulin of PMCA2 showed 30-fold higher affinity than PMCA4. PMCA2 exhibited a lower level of labelling in the autoinhibited conformation relative ...
Publisher: University of Delaware. Date Issued: 2015. Abstract: Structural mechanisms and underlying thermodynamic determinants of efficient internalization of charged cationic peptides (cell-penetrating peptides, CPPs) such as TAT, polyarginine, and their variants, into cells, cellular constructs, and model membrane/lipid bilayers (large and giant unilamellar or multilamelar vesicles) continue to garner significant attention. Two widely-held views on the translocation mechanism center on endocytotic and non-endocytotic (diffusive) processes. Using the translocation of short, charged cationic oligo-arginine peptides (mono-, di-, and tri-arginine) from bulk aqueous solution into model DMPC bilayers, we explore the question of the similarity of thermodynamic and structural predictions obtained from molecular dynamics simulations using all-atom and the Martini coarse-grain force fields. Specifically, we estimate potentials of mean force associated with translocation using standard all-atom ...
Struppe et al. (seven) researched the deuterium NMR spectra of Myr-d27-GNAAAAKKGSEQES (Cat14), the N-terminal 14-residue peptide from the catalytic subunit of cAMP-dependent protein kinase A (PKA), to illustrate how magnetically aligned neutral and acidic phospholipid bicelles can be utilized to characterize the purchasing and method of binding of peptides to membranes. Considering that Cat14 is electrically neutral, the most important conversation answerable for binding could be the insertion on the myristoyl team in the hydrophobic Main with the bilayer. The inclusion of twenty five% Phosphatidylserine (DMPS) or Phosphatidylglycerol (DMPG) into Phosphatidylcholine DMPC:DHPC bicelles leads to a reasonable rise in the this contact form ordering of the peptide relative on the bicelle ordinary, presumably as a result of favorable electrostatic interactions among the phospholipid headgroups and The 2 lysines in positions seven and eight. Productive preparation of acidic bicelles was realized by ...
This volume explores the creation, study, and processing of new liquid-crystalline polymers. It covers not only the chemistry of liquid-crystalline polymers, but also the physics and engineering aspects of these materials. A wide range of topics is covered, including syntheses of main-chain and side-chain LCPs, structural characterization of LP, rheology and processing, and applications such a electro-optics and self-reinforcing blends.
TV broadcasters are still wrapping their heads around 8K, but that isnt stopping NHK from pushing the technology forward. The Japanese industry giant is coming to the annual NAB trade show with a slew of 8K inventions, headlined by a high-speed camera. Its not exactly portable, but it can shoot 240 frames per second -- ideal for slow motion sports footage or reduced motion blur at full speed. Appropriately, theres dedicated hardware for stretching out playback at the extra-high resolution.
Get this from a library! Slow motion : stories about walking. [Andie Miller] -- Slow Motion is a collection of non-fiction stories (essays and interviews) about walking. The collection has been written over a period of six years and so the book has become something of a ...
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Get this from a library! India in slow motion. [Mark Tully; Gillian Wright] -- Probing into socio-political issues of post-independent India.
Nanodiscs are discoidal lipid bilayer (blue in the upper schemes) wrapped by two membrane scaffold proteins (MSP, green in upper schemes) in a belt-like configuration parallel to the disc-plane to shield the hydrophobic part of the phospholipids from the aqueous environment. ...