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Define dimenhydrinate. dimenhydrinate synonyms, dimenhydrinate pronunciation, dimenhydrinate translation, English dictionary definition of dimenhydrinate. n. A drug composed of two chemicals, diphenhydramine and 8-chlorotheophylline, used to prevent motion sickness. n a white slightly soluble bitter-tasting...
Dimenhydrinate, also known as Dramamine or Gravol, is an over-the-counter drug used to prevent nausea, vomiting, and dizziness caused by motion sickness. Dimenhydrinate is a combination drug composed of DB01075 and DB14132 in a salt form, with 53%-55.5% of diphenhydramine, and not less than 44%-47% of 8-chlorotheophylline, calculated on the dried basis. The antiemetic properties of dimenhydrinate are primarily thought to be produced by diphenhydramines antagonism of H1 histamine receptors in the vestibular system while the excitatory effects are thought to be produced by 8-chlorotheophyllines adenosine receptor blockade . The addition of 8-chlorotheophylline was initially intended to counteract the sedative effects of diphenhydramine. When used in large doses, dimenhydrinate has been shown to cause a high characterized by hallucinations, excitement, incoordination, and disorientation .
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Dimenhydrinate is generally used to prevent nausea and vomiting caused by motion sickness in dogs and cats. This medication may be used for other conditions as determined by your veterinarian.
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Dramamine affects certain receptors in central nervous system to treat dizziness, nausea, vomiting caused by sea and air sickness.
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noun antihistamine and antiemetic (trade name Dramamine) used to treat motion sickness • Syn: ↑Dramamine • Usage Domain: ↑trade name (for: ↑Dramamine) • Hypernyms: ↑antihistamine, ↑
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Abdominal blockage of iliohypogastric and ilio-inguinal nerves for management of post-caesarean pain: A novel method. Boztosun, Abdullah; Duger, Cevdet; Kosar, Mehmet Ilkay; Salk, Ismail; Gursoy, Sinan; Muderris, Iptisam Ipek; Yanik, Ali // South African Journal of Obstetrics & Gynaecology;Jan2012, Vol. 18 Issue 1, p23 Objective. The aim of this study was to compare pain relief after caesarean section achieved by an intra-abdominal iliohypogastric and ilio-inguinal (IHII) nerve block with levobupivacaine with that in patients given a placebo. Study design. A total of 60 healthy women scheduled for caesarean... ...
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