Staphylothermus marinus is a marine organism that was isolated from hydrothermal sediment off the the coast of Vulcano Island in Italy. It can also be found from black smokers on the ocean floor. In a rich medium, Staphylothermus marinus grows in an optimum temperature of 92 degrees Celsius, but when nutrients are sparce, the optimum temperature drops to 85 degrees Celsius. For growth in a lab, a complex nutrient source is needed for optimum growth. The morphology of the Staphylothermus marinus can differ depending on the nutrients available. When nutrients are plentiful, Staphylothermus marinus grow as giant cells in a slightly irregular coccus shape with diameters up to 15 mm. Low nutrient concentrations produce little cells with diameters ranging from 0.5 to 1.0 mm. Up to 100 of these cells can cluster together to form grape-like groups. S. marinus is related to Aeropyrum pernix, Hyperthermus butylicus, and Ignicoccus hospitalis. (5) Describe the appearance, habitat, etc. of the organism, ...
Im Rahmen dieser Arbeit wurde versucht, die A1AO ATP-Synthase von I. hospitalis zu reinigen und die Untereinheitenzusammensetzung des Komplexes zu bestimmen. Obwohl der gekoppelte Komplex erfolgreich durch das Detergenz DDM (n-Dodecyl-β-D-Maltopyranosid) aus der Membran herausgelöst werden konnte, war eine Reinigung des Gesamtkomplexes bisher nicht möglich. Zahlreiche Versuche, das Enzym über säulenchromatographische Verfahren zu reinigen, führten lediglich zu einer Anreicherung der dissoziierten A1- und AO-Subkomplexe der ATP-Synthase. Eine Identifizierung der Untereinheiten war durch eine Kombination von 2D-Native/SDS-PAGE, Western-Blot-Analysen und MALDI-TOF MS/MS möglich. So konnte die in vivo Expression von acht annotierten Untereinheiten der ATP-Synthase (A, B, C, D, E, F, a(I) und c(K)) bestätigt und das Protein Igni1215 als Bestandteil der ATP-Synthase (Untereinheit H) identifiziert werden. Die beiden erhaltenen Subkomplexe bestanden aus A, B, E und F (A1) und aus C, D, H und a ...
Uncurated}} {{Biorealm Genus}} ==Classification== ===Higher order taxa=== Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales; Desulfurococcaceae; Staphylothermus ===Species=== Staphylothermus marinus NCBI: [http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Tree&id=2&lvl=3&lin=f&keep=1&srchmode=1&unlock Taxonomy] ==Description and significance== Staphylothermus marinus is a hyperthermophilic, marine organism that was isolated from naturally heated sediment on the beach of Vulcano Island, Italy in 1986. It can also be found from black smokers on the ocean floor. In a rich medium, Staphylothermus marinus grows in an optimum temperature of 92 degrees Celsius, but when nutrients are sparce, the optimum temperature drops to 85 degrees Celsius. For growth in a lab, a complex nutrient source is needed for optimum growth. (1) The morphology of the Staphylothermus marinus can differ depending on the nutrients available. When nutrients are plentiful, ...
301167776 - EP 0624641 B1 2000-12-13 - Thermostable nucleic acid polymerase - [origin: EP0624641A2] The invention relates to purified thermostable DNA polymerases from Pyrodictium species, such as Pyrodictium occultum or Pyrodictium abyssi, which polymerases catalyze the combination of nucleoside triphosphates to form a nucleic acid strand complementary to a nucleic acid template strand. The preferred polymerases are characterized by their ability to function efficiently in a polymerase chain reaction, wherein said reaction includes repeated exposure to a denaturation temperature of about 100 DEG C. Most preferably the polymerases display 5 - 3 exonuclease activity, i.e. are proofreading enzymes. The invention also provides DNAs encoding the DNA polymerase activity of the said Pyrodictium species, which DNAs can be used to construct recombinant vectors and transformed host cells for production of polypeptides having said activity. The invention also relates to the preparation of said thermostable DNA
Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabolites: six-carbon compounds of glucose-6P and fructose-6P and three-carbon compounds of glycerone-P, glyceraldehyde-3P, glycerate-3P, phosphoenolpyruvate, and pyruvate [MD:M00001]. Acetyl-CoA, another important precursor metabolite, is produced by oxidative decarboxylation of pyruvate [MD:M00307]. When the enzyme genes of this pathway are examined in completely sequenced genomes, the reaction steps of three-carbon compounds from glycerone-P to pyruvate form a conserved core module [MD:M00002], which is found in almost all organisms and which sometimes contains operon structures in bacterial genomes. Gluconeogenesis is a synthesis pathway of glucose from noncarbohydrate precursors. It is essentially a reversal of glycolysis with minor variations of alternative paths [MD:M00003 ...
original description Stetter, K.O., Konig, H., and Stackebrandt, E. 1984. Pyrodictium gen. nov., a new genus of submarine disc-shaped sulphur reducing archaebacteria growing optimally at 105°C. Syst. Appl. Microbiol. 4:535-551. [details] ...
ID D7D8S0_STAHD Unreviewed; 420 AA. AC D7D8S0; DT 10-AUG-2010, integrated into UniProtKB/TrEMBL. DT 10-AUG-2010, sequence version 1. DT 11-DEC-2019, entry version 32. DE SubName: Full=ABC-2 type transporter {ECO:0000313,EMBL:ADI32166.1}; GN OrderedLocusNames=Shell_1062 {ECO:0000313,EMBL:ADI32166.1}; OS Staphylothermus hellenicus (strain DSM 12710 / JCM 10830 / BK20S6-10-b1 / OS P8). OC Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales; OC Desulfurococcaceae; Staphylothermus. OX NCBI_TaxID=591019 {ECO:0000313,EMBL:ADI32166.1, ECO:0000313,Proteomes:UP000002573}; RN [1] {ECO:0000313,Proteomes:UP000002573} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=DSM 12710 / JCM 10830 / BK20S6-10-b1 / P8 RC {ECO:0000313,Proteomes:UP000002573}; RG US DOE Joint Genome Institute; RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L., RA Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Larimer F., RA Land M., Hauser L., Kyrpides N., Mikhailova N., Anderson I.J., Woyke ...
No part of the universal evolutionary scenario gets more overhauls than the origin of life. Some say it began in the sea, some on the land. Some say it began at the bottom of the sea; others say that is the worst place for life to get going. The latest idea favors freshwater hot springs on land ...
Que la Chambre: a) déplore les pertes de vies humaines suite à lexplosion tragique survenue à Beyrouth le 4 août 2020; b) exprime sa solidarité avec le peuple libanais, en particulier avec les familles des plus de 150 personnes décédées, des plus de 6 000 personnes hospitalisées et des quelque 300 000 personnes qui se sont retrouvées sans abri à la suite de lexplosion; c) sengage à aider et à soutenir le peuple libanais dans son désir de réforme et de reconstruction durable et continue à soutenir la communauté libanaise, tant au Liban quici au Canada, en ces temps très difficiles ...
Rationnelle. La ventilation mécanique invasive (VI) saccompagne lorsquelle se prolonge, dune augmentation de la morbimortalité. Jusquà 64% des enfants hospitalisés aux soins intensifs sont ventilés et peu de données épidémiologiques existent afin destimer précocement la durée du support ventilatoire. Objectifs. Déterminer lincidence et les facteurs de risque précoces de ventilation mécanique invasive prolongée aux soins intensifs pédiatriques. Méthode. Nous avons conduit une étude descriptive rétroélective sur un an. Tous les épisodes de VI aux soins intensifs du Centre hospitalier universitaire Sainte Justine de Montréal ont été inclus. Les facteurs de risque de VI prolongée (≥ 96 heures) ont été déterminés par régression logistique. Résultats. Parmi les 360 épisodes de VI, 36% ont duré ≥ 96 heures. Les facteurs de risques de ventilation prolongée en analyse multivariée sont : âge ,12 mois, score de PRISM ≥ 15 à ladmission, pression moyenne dans ...
Une épidémie de salmonellose à Salmonella Enteridis lysotype PT4 dorigine alimentaire a eu lieu en Cumbria, au nord-ouest de lAngleterre, durant lété 2006. Quinze personnes, dont les échantillons de selles étaient positifs, correspondaient à la définition du cas ; trois dentre elles ont été hospitalisées, et lune de ces trois personnes est décédée.
Le bilan lavallois est désormais de 612 cas actifs selon les données émises par le Centre intégré de santé et de services sociaux (CISSS) de Laval. Cela signifie que le territoire connait une hausse de 12 cas actifs par rapport à la veille. Le total de décès augmente à 719 (+1) depuis le début de la pandémie. 90 tests positifs ont été effectués dans les 24 dernières heures. Ainsi, depuis le mois de mars, 10 580 citoyens lavallois ont été affectés par le virus. Parmi les personnes touchées par la COVID-19, 18 sont présentement hospitalisées, dont 2 aux soins intensifs. 34 employés de lorganisation de santé sont toujours absents du travail en raison de la COVID-19. Fabreville-Est/Sainte-Rose connait encore la plus forte augmentation du dernier bilan avec 19 nouveaux cas confirmés. Ce secteur est désormais le deuxième plus affecté de lîle Jésus avec un taux dinfection de 260 cas par 100 000 habitants sur les deux dernières semaines. Il est devancé par Pont-Viau/Renaud
The question of which proteins are involved in the interaction cell-cell contact and in transport between these two archaea cannot be addressed, at least presently, by genetics, such as mutagenesis or knockouts. We have therefore chosen the direct approach, by isolating a complex of membrane and membrane-associated proteins, using detergent-induced solubilization, followed by size-exclusion chromatography.. In the analysis of all proteins identified to be present in the detergent-solubilized membranes, approx. 26% of the I. hospitalis proteins, but only 4.2% of the N. equitans proteins belong to the category Transport and metabolism. This reflects the known difference between both organisms in their physiology and genome capacity: whereas I. hospitalis has the ability to grow alone and has a genome with full capacity for all biosynthetic pathways, N. equitans is not able to thrive alone and its genome is very compact and highly reduced; enzymes involved in many biosynthetic pathways cannot be ...
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Among the tRNA population of the archaeal parasite Nanoarchaeum equitans are five species assembled from separate 5 and 3 tRNA halves and four species derived from tRNA precursors containing introns. In both groups an intervening sequence element must be removed during tRNA maturation. A bulge-hel …
Within the cell free amino acids are probably fermentatively degraded by a pathway that is commonly found in anaerobic hyperthermophilic archaea [6,38]. In a first step amino groups are removed from the carbon skeleton by several distinct aminotransferases, which could be affiliated to class I/II (Tagg_0668), class III (Tagg_0004) and class V (Tagg_1145). The final acceptor of the released amino groups is likely 2-oxoglutarate thereby resulting in the accumulation of glutamate, which is subsequently oxidatively deaminated by the activity of a glutamate dehydrogenase (Tagg_1073). Upon deamination of amino acids the resulting 2-oxoacid derivates can be oxidatively decarboxylated to the respective coenzyme A (CoA) derivates by various 2-oxoacid-ferredoxin oxidoreductases having broad substrate specificity. Genes encoding subunits of all known archaeal 2-oxoacid-ferredoxin oxidoreductases could be identified in the T. aggregans genome and represent pyruvate-ferredoxin oxidoreductase ...
Biotin (vitamin H or vitamin B7) is the essential cofactor of biotin-dependent carboxylases, such as pyruvate carboxylase and acetyl-CoA carboxylase. Mammals cannot synthesize biotin, while in bacteria, fungi, and plants it is synthesized from pimelate thioester through different pathways. In E. coli and many organisms, pimelate thioester is derived from malonyl-ACP. The pathway starts with the methylation to malonyl-ACP methyl ester, followed by the fatty acid chain elongation cycle to form pimeloyl-ACP methyl ester, which is then demethylated to form pimeloyl-ACP [MD:M00572]. Pimeloyl-ACP is converted to biotin through the final four steps in the biotin bicyclic ring assembly, which are conserved among biotin-producing organisms [MD:M00123]. In B. subtilis, biotin is derived from pimeloyl-ACP formed by oxidative cleavage of long-chain acyl-ACPs [MD:M00573]. Some bacteria synthesize biotin from pimeloyl-CoA derived from pimelate [MD:M00577]. Biotin is covalently attached to biotin-dependent ...
Enzymatic Degradation of PrPSc by a Protease Secreted from Aeropyrum pernix K1. . Biblioteca virtual para leer y descargar libros, documentos, trabajos y tesis universitarias en PDF. Material universiario, documentación y tareas realizadas por universitarios en nuestra biblioteca. Para descargar gratis y para leer online.
S. cerevisiae 200x H. sapiens A. dubia $10/bp $0.1/bp Genomová sekvenace 6/ 25/ genomových projektů: 199 kompletních (včetně 28 eukaryontních) 508 prokaryotických genomů před dokončením 421 eukaryotických genomů před dokončením nejmenší: archaebacterium Nanoarchaeum equitans 500 kb Bacillus anthracis (anthrax) 5228 kb S. cerivisiae (kvasinka) 12,069 kb Arabidopsis thaliana 115,428 kb Drosophila melanogaster (octomilka) 137,000 kb Anopheles gambiae 278,000 kb Oryza sativa (rýže) 420,000 kb Mus musculus (myš) 2,493,000 kb Homo sapiens (člověk) 2,900,000 kb www. genomesonline. org/ S. cerevisiae 200x H. sapiens A. dubia $10/bp $0.1/bp $0.01/bp
Arheju šūnu izmēri ir līdzīgi lielākajai prokariotu daļai - vidējais diametrs ap 1 μm. Vissīkākie starp arhejiem ir sugas Nanoarchaeum equitans pārstāvji - 0,4 μm. Šūnu forma ir visdažādākā. Sastopamas ir sfēriskas, iegarenas, spirāliskas, trīsstūra un taisnstūra formas. Daudziem arhejiem ir viciņas, kuru sastāvā, atšķirībā no baktērijām, ietilpst vairāku veidu flagellīni. Arheji nespēj sintezēt sarežģītus hidrolītiskus fermentus, tāpēc tie lielākoties spēj pārstrādāt tikai vienkāršākās organiskās vielas. Tomēr tie spēj eksistēt daudz plašākā ārējās vides diapazonā un ir mazāk no tās atkarīgi.. Bez 16S rRNS arhejiem ir arī citas unikālas īpatnības:. ...
Supplementary MaterialsSupplementary Physique 1. the third branch in the phylogenetic tree of life. While physically resembling bacteria, the mechanisms involved in genomic informational processing are more eukaryotic in nature. HR is usually one important process in which archaea employ proteins with strong eukaryotic homology. One of the best studied models from this domain is the hyperthermophilic crenarchaeon also encodes three SsoRadA recombinase paralogs, whose function in HR is not well understood [2,14C16]. RadA paralogs to be examined is usually encoded by open reading frame Sso2452 in the P2 type-strain. The protein is a member of the aRadC family and has been referred to in the MK-1775 cost literature as RadB, Sso2452 (the open reading frame designation in the type-strain), and SsoRal1 [14,15,18,19]. The RadB name was widely abandoned following the description of a protein motif present only in euryarchaeal RadB sequences but absent in the crenarchaea [19]. Our laboratory has adopted ...
In publishing the research results obtained by use of the BIOLOGICAL RESOURCE, the USER is expected to cite the literature specified by the DEPOSITOR ...
Mass vs. Weight - Whats the difference? Mass is a fundamental, inherent property of matter that does not depend upon its location. Weight is the effect of gravity on mass.
ID AEPER1_1_PE483 STANDARD; PRT; 370 AA. AC AEPER1_1_PE483; Q9YE84; DT 00-JAN-0000 (Rel. 1, Created) DT 00-JAN-0000 (Rel. 2, Last sequence update) DT 00-JAN-0000 (Rel. 3, Last annotation update) DE RecName: Full=Putative methylthioribose-1-phosphate isomerase; DE Short=M1Pi; Short=MTR-1-P isomerase; EC=5.3.1 23;AltName: Full=MTNA-like DE protein; Short=aMTNA;AltName: Full=S-methyl-5-thioribose-1-phosphate DE isomerase; (AEPER1_1.PE483). GN OrderedLocusNames=APE_0686; OS AEROPYRUM PERNIX K1. OC Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales; OC Desulfurococcaceae; Aeropyrum. OX NCBI_TaxID=272557; RN [0] RP -.; RG -.; RL -.; CC -!- SEQ. DATA ORIGIN: Translated from the HOGENOM CDS AEPER1_1.PE483. CC Aeropyrum pernix K1, complete genome. CC annotated by Ensembl Genomes CC -!- ANNOTATIONS ORIGIN:MTNA_AERPE CC -!- FUNCTION: Catalyzes the interconversion of methylthioribose-1- CC phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) CC (By similarity). CC -!- CATALYTIC ACTIVITY: ...
Archaea are divided into two main groups based on rRNA trees, the Euryarchaeota and Crenarchaeota. Two other groups have been tentatively created for certain environmental samples and the peculiar species Nanoarchaeum equitans, discovered in 2002 by Karl Stetter, but their affinities are uncertain. Woese argued that the bacteria, archaea, and eukaryotes each represent a primary line of descent that diverged early on from an ancestral progenote with poorly developed genetic machinery. This hypothesis is reflected in the name Archaea, from the Greek archae or ancient. Later he treated these groups formally as domains, each comprising several kingdoms. This division has become very popular, although the idea of the progenote itself is not generally supported. Some biologists, however, have argued that the archaebacteria and eukaryotes arose from specialized eubacteria. The relationship between Archaea and Eukarya remains an important problem. Aside from the similarities noted above, many genetic ...
Sako, Y., Nomura, N., Uchida, A., Ishida, Y., Morii, H., Koga, Y., Hoaki, T., and Maruyama, T. 1996. Aeropyrum pernix gen. nov., sp. nov., a novel aerobic hyperthermophilic archaeon growing at temperatures up to 100 degrees C. Int. J. Syst. Bacteriol. 46:1070-1077 ...
A nanoscale antibody first found in camels combined with a protein-degrading molecule is an effective new platform to control protein levels in cells, according to Rice University scientists. The technique could aid fundamental research into cellular dynamics as well as the design of synthetic gene circuits.
Hyperthermophilic Archaea and Bacteria are an extraordinarily important class of organisms for which genetic tools remain to be developed. Unique technological obstacles to this goal are posed by the thermophilic and, in some cases, strictly anaerobic nature of these organisms. However, recent advan …
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Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H/ACA, box C/D and box C/D sRNAs.
Proteome IDi ,p>The proteome identifier (UPID) is the unique identifier assigned to the set of proteins that constitute the ,a href=http://www.uniprot.org/manual/proteomes_manual>proteome,/a>. It consists of the characters UP followed by 9 digits, is stable across releases and can therefore be used to cite a UniProt proteome.,p>,a href=/help/proteome_id target=_top>More...,/a>,/p> ...
Both biopharmaceutical companies Relypsa Inc (NASDAQ:RLYP) and Pernix Therapeutics Holdings Inc (NASDAQ:PTX) run into obstacles amidst preparing for the la
Accepted name: cysteate synthase. Reaction: O-phospho-L-serine + sulfite = L-cysteate + phosphate. Other name(s): sulfite:O-phospho-L-serine sulfotransferase (phosphate-hydrolysing, L-cysteate-forming).. Systematic name: sulfite:O-phospho-L-serine sulfonotransferase (phosphate-hydrolysing, L-cysteate-forming).. Comments: A pyridoxal-phosphate protein. It is highly specific for O-phospho-L-serine and sulfite. The reaction proceeds through a dehydroalanine (2-aminoacrylic acid) intermediate. The enzyme from Methanosarcina acetivorans is evolutionarily related to threonine synthase (EC 4.2.3.1), but the reaction is more similar to that of O-phosphoserine sulfhydrylase (EC 2.5.1.65).. Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: References:. 1. Graham, D.E., Taylor, S.M., Wolf, R.Z. and Namboori, S.C. Convergent evolution of coenzyme M biosynthesis in the Methanosarcinales: cysteate synthase evolved from an ancestral threonine synthase. Biochem. J. 424 (2009) ...
Klasifikace archeí je i dnes neustále v pohybu. Současné systémy se snaží seskupovat organismy na základě jejich skutečné příbuznosti.[13] Velkou roli v systematice hrají sekvence genů pro ribozomální RNA, díky nimž lze příbuzenské vztahy odhalit.[14] Většina z těch nejznámějších archeí se dnes řadí do dvou kmenů, Euryarchaeota a Crenarchaeota. Přesto existují a jsou nadále objevovány i další kmeny, například druh Nanoarchaeum equitans, objevený v roce 2003, je klasifikován v samostatném kmeni Nanoarchaeota.[15] Pro hrstku neobvyklých termofilních archeí se zase zavedl kmen Korarchaeota.[16][17] Podobně byl pro druhy Nitrosopumilus maritimus, Cenarchaeum symbiosum a příbuzná mezofilní archaea zaveden kmen Thaumarchaeota.[18] Sekvenování archeálních genomů přineslo objevy dalších odlišných linií: V roce 2011 byl navržen nový kmen Aigararchaeota pro archeum Caldiarchaeum subterraneum, nalezené v geotermálních vodách v podzemním ...
Endoplasmic-reticulum-associated protein degradation (ERAD) designates a cellular pathway which targets misfolded proteins of the endoplasmic reticulum for ubiquitination and subsequent degradation by a protein-degrading complex, called the proteasome. The process of ERAD can be divided into three steps: The recognition of misfolded or mutated proteins depends on the detection of substructures within proteins such as exposed hydrophobic regions, unpaired cysteine residues and immature glycans. In mammalian cells for example, there exists a mechanism called glycan processing. In this mechanism, the lectin-type chaperones calnexin/calreticulin (CNX/CRT) provide immature glycoproteins the opportunity to reach their native conformation. They can do this by way of reglucosylating these glycoproteins by an enzyme called UDP-glucose-glycoprotein glucosyltransferase. Terminally misfolded proteins, however, must be extracted from CNX/CRT. This is carried out by members of the EDEM (ER ...
Advancement of Sustainable Medical Innovations. There is declining productivity in biomedical research and development in terms of new product approvals, in part due to an inherently risk averse regulatory pathway for novel healthcare innovations. This is despite major achievements and opportunities in novel technological platforms. The portfolio of risk:benefit methodologies have been applied inconsistently and often conflated with cost-effective analysis. This yields results that do not effectively inform clinical practice or strategies for biomedical innovation. This investigation aims to assess risk:benefit appraisal methodologies in the analysis of published randomized controlled trials for pre-licensure biomedical.. Targeting the Senescence-Associated Secretory Phenotype, Buck Institute for Research on Aging. Senescent cells also develop resistance to signals for apoptosis (cellular suicide) and secrete inflammatory signaling molecules and protein-degrading enzymes into their local ...
Affiliation:国立研究開発法人産業技術総合研究所,その他部局等,研究員, Research Field:Applied molecular and cellular biology,Applied materials science/Crystal engineering,Digestive surgery,Functional biochemistry,Laboratory medicine, Keywords:糖鎖,NMR,糖認識ドメイン,レクチン,蛋白質,Aeropyrum pernix K1,進化,Aminoacyl-tRNA synthetase,肝線維化,バイオマーカー, # of Research Projects:7, # of Research Products:27, Ongoing Project:動脈硬化性大動脈瘤の網羅的糖鎖解析による新たな疾患関連指標の探索
Opko Health (NASDAQ: OPK) and Pernix Therapeutics (NASDAQ:PTX) are both healthcare companies, but which is the better stock? We will compare the two businesses based on the strength of their valuation, profitability, dividends, analyst recommendations, risk, earnings and institutional ownership. Institutional & Insider Ownership 22.9% of Opko Health shares are owned by institutional investors. Comparatively, […]
2) 4-phosphonooxy-L-threonine + 2-oxoglutarate = (3R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + L-glutamate. For diagram, click here or here or here for mechanism click here.. Other name(s): PSAT; phosphoserine aminotransferase; 3-phosphoserine aminotransferase; hydroxypyruvic phosphate-glutamic transaminase; L-phosphoserine aminotransferase; phosphohydroxypyruvate transaminase; phosphohydroxypyruvic-glutamic transaminase; phosphoserine aminotransferase; 3-O-phospho-L-serine:2-oxoglutarate aminotransferase; SerC; PdxC; 3PHP transaminase. Systematic name: O-phospho-L-serine:2-oxoglutarate aminotransferase. Comments: A pyridoxal-phosphate protein. This enzyme catalyses the second step in the phosphorylated pathway of serine biosynthesis in Escherichia coli [2,3]. It also catalyses the third step in the biosynthesis of the coenzyme pyridoxal 5-phosphate in Escherichia coli (using Reaction 2 above) [3]. In Escherichia coli, pyridoxal 5-phosphate is synthesized de novo by a pathway that involves EC ...
View Notes - 22 from BIOL 4125 at LSU. PROKARYOTIC DIVERSITY BIOL 4125 SPRING 2009 LECTURE 22 Hyperthermophilic Archaea Part II The early overview of archaeal diversity was exemplified by a
A novel, regular to irregular, coccoid-shaped, anaerobic, Fe(III)-reducing microorganism was isolated from the Guaymas Basin hydrothermal system at a depth of 2000 m. Isolation was carried out with a new technique using Fe(III) oxide as the electron acceptor for the recovery of colonies on solid medium. The isolate, designated strain 234T, was strictly anaerobic and exhibited a tumbling motility. The cells had a single flagellum. Strain 234T grew at temperatures between 65 and 90 degrees C, with an optimum at about 88 degrees C. The optimal salt concentration for growth was around 19 g l(-1). The isolate was capable of growth with H2 as the sole electron donor coupled to the reduction of Fe(III) without the need for an organic carbon source. This is the first example of a dissimilatory Fe(III)-reducing micro-organism capable of growing autotrophically on hydrogen. In addition to molecular hydrogen, strain 234T oxidizes pyruvate, acetate, malate, succinate, peptone, formate, fumarate, yeast ...
The location of hyperthermophilic organisms in the tree of life has been the source of many exciting discussions during the last two decades. It inspired not only novel hypotheses for the early evolution of the organisms, but also the isolation of many new species of Archaea and Bacteria from hot environments, as well as microbial genome sequencing and phylogenomic analyses. In view of the new wealth of genetic information generated from several analysed genomes of the hyperthermophiles, we can only conclude that the question of their exact phylogenetic location and evolutionary origin is presently as open as ever before.. ...
The virions of members of the Guttaviridae have an ovoid shape, measuring 55 x 75 nm (for Aeropyrum pernix ovoid virus 1 (APOV1), Betaguttavirus) to 80 x 130 nm (for Sulfolobus newzealandicus droplet-shaped virus (SNDV), Alphaguttavirus), when analysed by cryo-electron microscopy [{Arnold et al., 2000:10873785RJOHTXArnold et al., 2000, SNDV, a novel virus of the extremely thermophilic and acidophilic archaeon Sulfolobus, Virology, 272, 2, 409-16RJOMREFMochizuki et al., 2011:21784945RJOHTXMochizuki et al., 2011, Provirus induction in hyperthermophilic archaea: characterization of Aeropyrum pernix spindle-shaped virus 1 and Aeropyrum pernix ovoid virus 1, J Bacteriol, 193, 19, 5412-9}]. The virion surface is covered by globular subunits, which are ~3.5 nm in width. In negative-contrast electron micrographs, the virions are slightly pleomorphic, most displaying a droplet-like shape. Virions of SNDV are decorated with dense filaments attached to the pointed end of the virion; such appendages were ...
Dr. Jason Russ, MD is a hospital medicine specialist in Indianapolis, IN. Dr. Russ completed a residency at Indiana University / School of Medicine. He currently practices at IU Health Physicians Hospitalis and is affiliated with IU Health Methodist Hospital.
Common Name The Leaf-Riding Maxilllaria Flower Size 1 1/4 [3 cm] Found in Colombia, Ecuador, Peru as well as Venezuela, Brazil and Bolivia, in wet montane forests at an altitude of 200 to 1500 metersas a small to medium sized, hot to cool growing, caespitose, pseudobulbless epiphyte with an erect stem carrying many fleshy, bilaterally flattened, straight or recurved leaves which in youth is fully covered and with age, only has leaves towards the apex and has old grey leaf bases below. This species blooms in the spring and fall on a short, axillary, single flowered inflorescence arising from and held near the leaf axils. This species has a decided Vandanaceous or giant equitant-look to it as it has no pseudobulbs and has bilaterally compressed, imbricating leaves. Synonyms *Camaridium equitans Schltr. 1920; Camaridium vandiforme Schltr. 1925; Heterotaxis equitans (Schltr.) Ojeda & Carnevali 2005; Marsupiaria equitans (Schltr.) Hoehne 1947; Marsupiaria mattogrossensis (Brade) Hoehne 1947; ...
Grote, R., Li, L., Tamaoka, J., Kato, C., Horikoshi, K., and Antranikian, G. Thermococcus siculi sp. nov., a novel hyperthermophilic archaeon isolated from a deep-sea hydrothermal vent at the mid-Okinawa Trough. Extremophiles (1999) 3:55-62 ...
MORRISTOWN, N.J., May 09, 2016-- Pernix Therapeutics Holdings, Inc., a specialty pharmaceutical company, today announced that on May 6, 2016, the Patent Trial and Appeal Board of the United States Patent and Trademark Office denied a petition for inter partes review filed by Graybar Pharmaceuticals, LLC against Pozen, Inc. This petition, which was filed on November...
Pernix Therapeutics Holdings Inc (NASDAQ:PTX) announced the distribution of TREXIMET® (sumatriptan and naproxen sodium) 10/60 mg to wholesalers has
O-phospho-L-serine---tRNA ligase ( EC 6.1.1.27 , O-phosphoseryl-tRNA ligase, non-canonical O-phosphoseryl-tRNA synthetase, SepRS) is an enzyme with systematic name O-phospho-L-serine:tRNACys ligase (AMP-forming). This enzyme catalyses the following chemical reaction : In organisms like Archaeoglobus fulgidus , this enzyme ligates O-phosphoserine to tRNACys. References Fukunaga, R.; Yokoyama, S. (2007).
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