TY - JOUR. T1 - Medical and economic benefit of a comprehensive infection control program that includes routine determination of microbial clonality. AU - Hacek, Donna M.. AU - Suriano, Terra. AU - Noskin, Gary A.. AU - Kruszynski, Julie. AU - Reisberg, Boris. AU - Peterson, Lance R.. PY - 1999. Y1 - 1999. N2 - Nosocomial infections are a major part of the problem of reemerging pathogens causing infectious diseases, affecting 5% of patients hospitalized in the United States during 1995. We assessed the medical and economic effects on the overall nosocomial infection rate of an intervention that provided an enhanced, integrated infection control program, including an in- house molecular typing laboratory capability to rapidly assess microbial clonality. Data on nosocomial infections for 24 months prior to the change in approach to infection control were compared with data from the 24 months immediately following implementation of the new program. Infections per 1,000 patient-days and percentage ...
Antimicrobial-Resistant Pathogens Associated with Healthcare-Associated Infections Summary of Data Reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2009-2010 - Volume 34 Issue 1 - Dawn M. Sievert, Philip Ricks, Jonathan R. Edwards, Amy Schneider, Jean Patel, Arjun Srinivasan, Alex Kallen, Brandi Limbago, Scott Fridkin, National Healthcare Safety Network (NHSN) Team and Participating NHSN Facilities
We carried out a systematic review and meta-analysis of randomized trials to explore the effectiveness of oral chlorhexidine on nosocomial pneumonia, causative bacteria, and mortality. PubMed, Embase, and the Cochrane Register of Controlled Trials were searched for randomized trials in critically ill patients receiving oral chlorhexidine. Odds ratios (OR) were pooled with the random effects model. Twenty-two randomized trials including 4277 patients were identified. Chlorhexidine significantly reduced the incidence of nosocomial pneumonia (OR 0.66; 95% confidence interval [CI] 0.51-0.85) and ventilator-associated pneumonia (OR 0.68, 95% CI 0.53-0.87). There was a significant reduction of nosocomial pneumonia due to both Gram-positive (OR 0.41; 95% CI 0.19-0.85) and Gram-negative (OR 0.68; 95% CI 0.51-0.90) bacteria, but only pneumonia due to normal flora (OR 0.51; 95% CI 0.33-0.80). The subgroup analysis revealed a significant benefit of chlorhexidine on nosocomial pneumonia in surgical ...
In this study, antimicrobial resistance profiles were determined for 748 isolates of Escherichia coli from patients with acute nosocomial urinary tract infections (UTIs) at a Turkish Training Hospital. Thirteen antibiotics were included. Resistance to ampicillin alone (45.1%) and ciprofloxacin alone (20.6%) were the most commonly identified single resistances. Multiple resistance was found in 49.7% of the strains. The most common multiple antibiotic resistance profiles included ampicillin-sulbactam/amoxycilline-clavulonate (4.0%) and ampicillin-sulbactam/trimethoprim-sulfamethoxazole/amoxycilline-clavulonate (2.8%). From 2004 to 2006, ampicillin, trimethoprim-sulfamethoxazole and ciprofloxacin resistant strains increased to 76% from 57%, 53% from 43% and 55% from 41%, respectively. The percentage of extended-spectrum β-lactamase (ESBL) producing strains was 7.8% and imipenem resistance was seen in 5.2% of ESBL positive strains. We conclude that clinically important E.coli strains have now ...
BACKGROUND: Strategies to prevent Staphylococcus aureus infection in hospitals focus on patient-to-patient transmission. We used whole-genome sequencing to investigate the role of colonized patients as the source of new S. aureus acquisitions, and the reliability of identifying patient-to-patient transmission using the conventional approach of spa typing and overlapping patient stay. METHODS: Over 14 months, all unselected patients admitted to an adult intensive care unit (ICU) were serially screened for S. aureus. All available isolates (n = 275) were spa typed and underwent whole-genome sequencing to investigate their relatedness at high resolution. RESULTS: Staphylococcus aureus was carried by 185 of 1109 patients sampled within 24 hours of ICU admission (16.7%); 59 (5.3%) patients carried methicillin-resistant S. aureus (MRSA). Forty-four S. aureus (22 MRSA) acquisitions while on ICU were detected. Isolates were available for genetic analysis from 37 acquisitions. Whole-genome sequencing indicated
The Healthcare-Associated Infections Surveillance Network (HAI-Net) is a European network for the surveillance of healthcare-associated infections (HAI). The network is coordinated by the ECDC.. Activities of the Healthcare-associated Infections Surveillance Network (HAI-Net) are:. ...
article{1887963, author = {Reunes, Sofie and Rombaut, Vicky and Vogelaers, Dirk and Brusselaers, Nele and Lizy, Christelle and Cankurtaran, Mustafa and Labeau, Sonia and Petrovic, Mirko and Blot, Stijn}, issn = {0953-6205}, journal = {EUROPEAN JOURNAL OF INTERNAL MEDICINE}, keyword = {ANTIMICROBIAL THERAPY,HOSPITAL MORTALITY,MULTIDRUG-RESISTANCE,OLD PATIENTS,ATTRIBUTABLE MORTALITY,Bloodstream infection,Elderly,Risk factors,Geriatric patient,Mortality,CRITICALLY-ILL PATIENTS,CARE-UNIT PATIENTS,INTENSIVE-CARE,PSEUDOMONAS-AERUGINOSA,BACTEREMIA}, language = {eng}, number = {5}, pages = {e39--e44}, title = {Risk factors and mortality for nosocomial bloodstream infections in elderly patients}, url = {http://dx.doi.org/10.1016/j.ejim.2011.02.004}, volume = {22}, year = {2011 ...
November 19, 2016 at 8:03 am Antimicrob. Agents Chemother. November 2016 V.60 N.11 P.:6787-6794. Laura F. Mataseje, Kahina Abdesselam, Julie Vachon, Robyn Mitchel, Elizabeth Bryce, Diane Roscoe, David A. Boyd, Joanne Embree, Kevin Katz, Pamela Kibsey, Andrew E. Simor, Geoffrey Taylor, Nathalie Turgeon, Joanne Langley, Denise Gravel, Kanchana Amaratunga, and Michael R. Mulvey , on behalf of the Canadian Nosocomial Infection Surveillance Program. aAntimicrobial Resistance and Nosocomial Infections, Public Health Agency of Canada, Winnipeg, MB, Canada. bCenter for Communicable Diseases and Infection Control, Public Health Agency of Canada, Ottawa, ON, Canada. cDepartment of Pathology and Laboratory Medicine, Vancouver General Hospital, Vancouver, BC, Canada. dDepartment of Pediatrics and Child Health, University of Manitoba, Winnipeg, MB, Canada. eDepartment of Infection Prevention and Control, North York General Hospital, Toronto, ON, Canada. fDepartment of Laboratory Medicine, Victoria General ...
The NHSN is a secure, Internet-based surveillance system that expands and integrates patient and healthcare personnel safety surveillance systems managed by the Division of Healthcare Quality Promotion (DHQP) at the Centers for Disease Control and Prevention. In addition, facilities that participate in certain reporting programs operated by the Centers for Medicare and Medicaid Services (CMS) can do so through use of NHSN. Furthermore, some U.S. states use NHSN as a means for healthcare facilities to submit data on healthcare-associated infections (HAIs) mandated through their specific state legislation ...
September 2016 - BronchUK team publish on Pseudomonas and microbial cross infection and evolution in bronchiectasis in the European respiratory ...
The most frequent adverse event in the healthcare delivery system is acquisition of an infection within a healthcare facility. Since infection control measures are known, simple, and low-cost, we examine why the problem of healthcare-associated infections persists. Hundreds of millions of patients each year are affected by a healthcare-associated infection, with negative medical outcome and financial cost. It is a major public health problem even in countries with advanced healthcare systems. This is a bit perplexing, given that hygienic practices have been known and actively promoted. The objective is to address the question: doesnt the use of disinfection, sterilization, handwashing, and alcohol rubs prevent the spread of pathogenic organisms? We conclude that the persistent high prevalence of nosocomial infections despite known hygienic practices is attributable to two categories of factors: biological and inherent shortcomings of some practices (considered in Part 1), and human factors (considered
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The system used by the National Nosocomial Infection Surveillance (NNIS) program to measure risk of surgical site infection uses a score of >3 on the American Society of Anesthesiologists (ASA)-physical status scale as a measure of underlying illness. The chronic disease score measures health status as a function of age, sex, and 29 chronic diseases, inferred from dispensing of prescription drugs. We studied the relationship between the chronic disease score and surgical site infection and whether the score can supplement the NNIS risk index. In a retrospective comparison of 191 patients with surgical site infection and 378 uninfected controls, the chronic disease score and ASA score were highly correlated. The chronic disease score improved prediction of infection by the NNIS risk index and augmented the ASA score for risk adjustment.
Establishing an Infection Control program for a long term health facility A thesis statement that will be the opening of the paper The working title of the paper Five subheadings that will be used in the paper.
In preparation for the teleclass, HARDWARE OR SOFTWARE? INTERVENTIONS FOR A SUSTAINABLE INFECTION CONTROL PROGRAM , you will need the following information: Speaker: Prof. Joost Hopman, Radboud University, The Netherlands Teleclass date: 22 September Time: 1:30pm-2:30pm in New York / Toronto … 6:30pm in London Teleclass Notes and Online Recording: http://webbertraining.com/schedulep1.php?command=viewDocs&ID=1307 Bridge Lines: 646-519-5860 (North…
PEOSH Model Tuberculosis Infection Control Program Revised November, 2004 NOTE: The information in this document is not considered to be a substitute for any provision of the PEOSH Act or for any standards
Background: Nosocomial infections (NIs) constitute an important worldwide health problem with high morbidity and mortality rate as well as economic consequences. We aimed to determine incidence of nosocomial infection in surgical intensive care unit (SICU). Aims & Objectives: To find out incidence of nosocomial infection in surgical intensive care unit (SICU) at a large teaching hospital in North India. Methods: A prospective cohort study was conducted during a period of one year from 1st Oct 2013 to 30th Sep 2014 in SICU of SKIMS. The researcher visited the SICU on daily basis at 10 am in the morning to note down presence or absence of signs and symptoms of nosocomial infection as per the laid down criteria. The researcher used inpatient records, interacted with clinical staff to establish absence or presence of nosocomial infection. Criteria for establishment of nosocomial infections were adopted in accordance with the simplified definition derived from the Centre for disease control, USA. ...
A study of newly installed, hands-free faucets at The Johns Hopkins Hospital, all equipped with the latest electronic-eye sensors to automatically detect hands and dispense preset amounts of water, shows they were more likely to be contaminated with one of the most common and hazardous bacteria in hospitals compared to old-style fixtures with separate handles for hot and cold water. Newer is not necessarily better when it comes to infection control in hospitals, especially when it comes to warding off potential hazards from water-borne bacteria, such as Legionella species, says senior study investigator and infectious disease specialist Lisa Maragakis, M.D., M.P.H. New devices, even faucets, however well intentioned in their make-up and purpose, have the potential for unintended consequences, which is why constant surveillance is needed, says Maragakis, director of hospital epidemiology and infection control at Hopkins Hospital and an assistant professor at the Johns Hopkins University ...
To determine the most effective infection control procedure in preventing nosocomial infection with respiratory syncytial virus (RSV), we did a prospective controlled study of four infection-control strategies in four wards in a large paediatric hospital in the west of Scotland. All children under two years old admitted to four general wards during three winter RSV epidemics (1989-92) were screened for RSV infection (by nasopharyngeal aspirate and direct immunofluorescence) within 18 hours of admission. The main outcome measure was the occurrence of nosocomial infection, defined as the number of children initially RSV negative who became RSV positive 7 days or more after hospital admission (incubation period for RSV infection is 5-8 days). Without special precautions, there was a high rate of nosocomial RSV infection (26%). Nosocomial infection was significantly reduced by the combination of cohort nursing with the wearing of gowns and gloves for all contacts of RSV-infected children ...
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1 Infection Control Hospital Epidemiology 2008; 29:1074-1076 2 Dancer SJ., Importance of the environment in meticillin-resistant Staphylococcus aureus acquisition: the case for hospital cleaning. Lancet Infect Dis 2007:70241e70244. doi: 10.1016/S1473-3099(07). 3 M. Galuty, et al.; Clinical Findings, Healthcare Uniforms and Infections, Presented at the Infectious Diseases Society of America Conference, 2008 4 C. J. Uneke and P. A. Ijeoma, The Potential for Nosocomial Infection Transmission by White Coats Used by Physicians in Nigeria: Implications for Improved Patient-Safety Initiatives; World Health & Population Vol. 11 No. 3 2010 5 Trillis F. Contamination of Hospital Curtains With Healthcare-Associated Pathogens. Infection Control and Hospital Epidemiology. November 2008. 6 P. Gaspard, et al.; Meticillin-resistant Staphylococcus aureus contamination of healthcare workers uniforms in long-term care facilities; Journal of Hospital Infection (2009) 71, 170-175 ...
ATLANTA -- Amid growing concern about the rise in hospital-acquired infections (HAIs), McKesson Provider Technologies and the Clorox Company today announced a strategic relationship focused on helping customers enhance patient safety. Clorox and McKesson together will develop and promote disinfection protocols for mobile equipment and handheld electronic devices. These devices which include computers on wheels, tablet PCs, mobile medication cabinets, and hand-held bar-code scanners for medication administration, specimen tracking and blood verification are commonly used by clinicians in and between patient rooms.
Grinnell Medical Center partnered with Grinnell College to study how copper surfaces could reduce hospital-acquired infections and, sure enough, biology students found that by using copper (instead of plastic and wood) on high-touch surfaces within a hospital setting (such as grab bars, keyboards, switches and sinks), they were able to dramatically reduce the amount of bacteria present.
Background: Health care-associated infections (HAIs) are a global health burden because of their significant impact on patient health and health care systems. Mechanistic simulation modeling that captures the dynamics between patients, pathogens, and the environment is increasingly being used to improve understanding of epidemiological patterns of HAIs and to facilitate decisions on infection prevention and control (IPC). The purpose of this review is to present a systematic review to establish (1) how simulation models have been used to investigate HAIs and their mitigation and (2) how these models have evolved over time, as well as identify (3) gaps in their adoption and (4) useful directions for their future development. Methods: The review involved a systematic search and identification of studies using system dynamics, discrete event simulation, and agent-based model to study HAIs. Results: The complexity of simulation models developed for HAIs significantly increased but heavily ...
Residents of long-term care facilities for the elderly are vulnerable to health care-associated infections. However, compared to medical institutions, long-term care facilities for the elderly lag behind in health care-associated infection control and prevention. We conducted a epidemiologic study to clarify the current status of infection control in long-term care facilities for the elderly in Japan. A questionnaire survey on the aspects of infection prevention and control was developed according to SHEA/APIC guidelines and was distributed to 617 long-term care facilities for the elderly in the province of Osaka during November 2016 and January 2017 ...
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According to a new Centers for Disease Control and Prevention (CDC) report, ongoing efforts are needed to combat infections impacting hospital patients and more work is needed to improve patient safety. According to the CDC, approximately one in 25 US patients contracts at least one infection during the course of their hospital care and every day, more than more than 200 Americans with healthcare-associated infections (HAIs) will die during their hospital stay. The CDCs HAI Progress Report showed minimal decreases for both hospital-onset Clostridium difficile (C.diff) infections and hospital-onset methicillin-resistant Staphylococcus aureus (MRSA) bloodstream infections.. Xenex Disinfection Services pulsed xenon UV light room disinfection system has been repeatedly proven effective against C. diff and MRSA in the laboratory and in patient outcome results at hospitals utilizing Xenex devices.. Hospital cleanliness plays a role in the spread of HAIs, which are caused by microorganisms such as C. ...
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541 ...
a) Routine surveillance, outbreak investigations and interventions including pathogen distributions and antimicrobial susceptibility profiles consistent with the 2006 CDC health care infection control practices advisory committee guideline, Management of Multidrug-Resistant Organisms in Healthcare Settings ...
In the old paradigm, infection prevention programs (known then as infection control programs) focused on surveillance for infections, primarily in ICUs, calculating infection rates, and then feeding back the rates to the leadership of the ICUs. The thinking was that the unit leaders would review the data and develop ways to reduce the rates, though in reality this rarely happened. The infection prevention program wasnt very interested in how to reduce the infection rates, except perhaps to elucidate what the risk factors for infection might be. Hands-on design and implementation of interventions was not seen as a part of the day-to-day work. Another core function was identification and control of outbreaks of nosocomial infections, which were not infrequent. But in a fee-for-service reimbursement model, there was no financial incentive for hospitals to reduce infection rates. Actually, the opposite was true-more healthcare-associated infections generated more services, which generated more ...
Methods: We retrospectively reviewed all patients with AML over a 5-year period between 2007 and 2011 at the Childrens Hospital Colorado. Cases and controls were classified on the basis of the presence of a CLABSI as defined by the National Healthcare Safety Network.. Results: Of 40 patients in the study, 25 (62.5%) developed at least one CLABSI during therapy. The majority of CLABSIs were due to oral or gastrointestinal organisms (83.0%). Skin organisms accounted for 8.5%. In a multivariable analysis, the strongest risk factors associated with CLABSI were diarrhea (odds ratio [OR] 6.7, 95% confidence interval [CI] 1.6-28.7), receipt of blood products in the preceding 4-7 days (OR 10.0, 95%CI 3.2-31.0), not receiving antibiotics (OR 8.3, 95%CI 2.8-25.0), and chemotherapy cycle (OR 3.5, 95%CI 1.4-8.9). CLABSIs led to increased morbidity, with 13 cases (32.5%) versus two controls (1.9%) requiring transfer to the pediatric intensive care unit (P , 0.001). Three (7.5%) of 40 CLABSI events resulted ...
This measure assesses antimicrobial use in hospitals based on medication administration data that hospitals collect electronically at the point of care and report via electronic file submissions to CDCs National Healthcare Safety Network (NHSN). The antimicrobial use data that are in scope for this measure are antibacterial agents administered to adult and pediatric patients in a specified set of ward and intensive care unit locations: medical, medical/surgical, and surgical wards and units. The measure compares antimicrobial use that the hospitals report with antimicrobial use that is predicted on the basis of nationally aggregated data. The measure is comprised of a discrete set of ratios, Standardized Antimicrobial Administration Ratios (SAARs), each of which summarizes observed-to-predicted antibacterial use for one of 16 antibacterial agent-patient care location combinations. The SAARs are designed to serve as high value targets or high level indicators for antimicrobial stewardship ...
Im glad that the new CDC Vitals Signs report, based upon a modeling study of the impact of regionally-coordinated interventions to reduce healthcare associated infections (HAIs) due to selected multiple drug resistant organisms (MDROs) and Clostridium difficile, is gaining some media attention. The investigators modeled three different scenarios for control: (1) status quo, (2) augmented efforts at selected individual facilities, and (3) augmented activities coordinated across a health care network. Using data from various sources to inform the model (Emerging Infections Program and National Healthcare Safety Network for disease burden; Orange County, California and the VA system for patient movement across healthcare facilities; and experience from the UK and Israel for reductions in MRSA, C. difficile, and carbapenem-resistant Enterobacteriaceae (CRE) after national interventions), the model suggests that prevention approaches coordinated by public health authorities could reduce HAIs due ...
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Healthcare-associated bloodstream infections are related to both increased antibiotic use and risk of adverse outcomes. An in-depth understanding of their epidemiology is essential to reduce occurrence and to improve outcomes by targeted prevention strategies. The objectives of the study were to determine the epidemiology, source and concordance of healthcare-associated bloodstream infections with clinical site isolates. We conducted a descriptive cross-sectional study in critically ill adults admitted to a tertiary semi-closed intensive care unit in England to determine the epidemiology, source and concordance of healthcare-associated bloodstream infections with clinical site isolates. All nosocomial positive blood cultures over a 4-year study period were identified. Pathogens detected and concordances with clinical site are reported as proportions. Contaminant pathogens accounted for half of the isolates. The most common non-contaminant pathogens cultured were Pseudomonas spp. (8.0%), Enterococcus spp
The Society for Healthcare Epidemiology of America (SHEA) and Centers for Disease Control and Prevention (CDC) have each released new tools and information to help track deadly healthcare-associated infections (HAIs) in nursing homes and other long-term care settings.
Odicef-T from Galpha, Ceftriaxone - Axone-SB to Cadizone | Ceftriaxone is a third-generation cephalosporin antibiotic. Use of Odicef-T from Galpha, Pregnancy, lactation in childrens and special precautions for Odicef-T from Galpha, prices of Odicef-T from Galpha . Like other third-generation cephalosporins, it has broad spectrum activity against Gram positive and Gram negative bacteria. In most cases, it is considered to be equivalent to cefotaxime in terms of safety and efficacy.Ceftriaxone is often used (in combination, but not direct, with macrolide and/or aminoglycoside antibiotics) for the treatment of community-acquired or mild to moderate health care-associated pneumonia. It is also a choice drug for treatment of bacterial meningitis. In pediatrics, it is commonly used in febrile infants between 4 and 8 weeks of age who are admitted to the hospital to exclude sepsis. The dosage for acute ear infection in the very young is 50 mg/Kg IM, one dose only. It has also been used in the treatment of Lyme
Articles in this issue include: The Essential Role of Pharmacists in Antimicrobial Stewardship Choosing Wisely in Healthcare Epidemiology and Antimicrobial Stewardship The Role of Nursing Homes in the Spread of Antimicrobial Resistance Over the Healthcare Network The Impact of Methicillin-Resistant Staphylococcus aureus (MRSA) and Vancomycin-Resistant Enterococcus (VRE) Flags on Hospital Operations Limiting the Number of…
The Centers for Disease Control and Prevention (CDC) announced the arrival of Get Smart About Antibiotics Week (observed November 14-20, 2011) by launching a new antibiotic tracking system that will allow hospitals to monitor antibiotic usage and compare themselves to other hospitals in the region or across the country. The electronic system is part of the CDCs National Healthcare Safety Network.
Cf. WX 167 for prevention and control of cross infection in hospitals; WU 29 for prevention and control of cross infection in dental health facilities or in the provision of dental care. ...
TY - JOUR. T1 - Elucidating the origins of nosocomial infections with Candida albicans by DNA fingerprinting with the complex probe Ca3. AU - Marco, F.. AU - Lockhart, S. R.. AU - Pfaller, M. A.. AU - Pujol, C.. AU - Rangel-Frausto, M. S.. AU - Wiblin, T.. AU - Blumberg, H. M.. AU - Edwards, J. E.. AU - Jarvis, W.. AU - Saiman, L.. AU - Patterson, J. E.. AU - Rinaldi, M. G.. AU - Wenzel, R. P.. AU - Soll, D. R.. PY - 1999/8/28. Y1 - 1999/8/28. N2 - Computer-assisted DNA fingerprinting with the complex probe Ca3 has been used to analyze the relatedness of isolates collected from individuals with nosocomial bloodstream infections (BSIs) and hospital care workers (HCWs) in the surgical and neonatal intensive care units (ICUs) of four hospitals. The results demonstrate that for the majority of patients (90%), isolates collected from commensal sites before and after collection of a BSI isolate were highly similar or identical to the BSI isolate. In addition, the average similarity coefficient for BSI ...
Start Preamble In accordance with section 10(a)(2) of the Federal Advisory Committee Act (Pub. L. 92-463), the Centers for Disease Control and Prevention (CDC) announces the following meeting. Name: Healthcare Infection Control Practices Advisory Committee. Times and Dates: 8:30 a.m.-5 p.m., October 21, 2002. 8:30 a.m.-4 p.m., October 22, 2002. Place: Swissotel, 3391 Peachtree Road, NE, Atlanta, Georgia 30333. Status: Open to the public, limited only by the space available. Purpose: The Committee is charged with providing advice and guidance to the Secretary; the Assistant Secretary for Health; the Director, CDC; and the Director, National Center for Infectious Diseases (NCID), regarding (1) the practice of hospital infection control; (2) strategies for surveillance, prevention, and control of infections (e.g., nosocomial infections), antimicrobial resistance, and related events in settings where healthcare is provided; and (3) periodic updating of guidelines and other policy statements ...
I was joined by Chair & Professor of Clinical Laboratory Science (CLS) and the Associate Dean for Research, College of Health Professions at Texas State University, Rodney Rohde, PhD on the Outbreak News This Week Radio Show for the full hour to discuss a myriad of topics concerning HAIs.. Topics covered include an insight into how big the problem is in the US, the types of infections and what procedures carry the most risk.. In addition, Dr. Rohde addressed specifically some of the most common and well known microbes that are implicated in HAIs-MRSA, Clostridium difficile (C. diff or CDI) and the issues with the emergence of multi-drug resistant gram negative bacilli infections like Klebsiella pneumoniae.. Other topics discussed include antibiotic stewardship and things the patient can do or ask about to keep informed and protected.. ...
Despite recent progress in the prevention and treatment of hospital-acquired infections, nosocomial pneumonia remains an important problem among critically ill patients. Nosocomial pneumonia develops in five to 10 patients per 1,000 admissions and has a mortality rate of 20%-50%. This review focuses …
Nosocomial diseases are contaminations which are procured in hospitals and other human services offices. To be delegated a nosocomial contamination, the patient more likely than not been conceded for reasons other than the disease. He or she should likewise have hinted at no dynamic or brooding contamination.. Nosocomial infections are brought on by pathogens that effortlessly spread through the body. Numerous hospital patients have traded off insusceptible frameworks, so they are less ready to battle off contaminations. Now and again, patients create contaminations because of poor conditions at a clinic or a social insurance office, or because of doctors facility staff not taking after legitimate methodology. A few patients obtain nosocomial diseases by communicating with different patients. Others experience microorganisms, growths, parasites, or infections in their healing facility environment.. ...
To determine the distribution and antimicrobial drug resistance in bacterial pathogens causing nosocomial infections, surveillance data on nosocomial infections documented from 1981 to 1999 at National Taiwan University Hospital were analyzed. During this period, 35,580 bacterial pathogens causing nosocomial infections were identified. Candida species increased considerably, ranking first by 1999 in the incidence of pathogens causing all nosocomial infections, followed by Staphylococcus aureus and Pseudomonas aeruginosa. Candida species also increased in importance as bloodstream infection isolates, from 1.0% in 1981-1986 to 16.2% in 1999. The most frequent isolates from urinary tract infections were Candida species (23.6%), followed by Escherichia coli (18.6%) and P. aeruginosa (11.0%). P. aeruginosa remained the most frequent isolates for respiratory tract and surgical site infections in the past 13 years. A remarkable increase in incidence was found in methicillin-resistant S. aureus (from ...
TY - JOUR. T1 - Outbreak due to methicillin- and rifampin-resistant Staphylococcus aureus. T2 - Epidemiology and eradication of the resistant strain from the hospital. AU - Bitar, C. M.. AU - Mayhall, C. G.. AU - Lamb, V. A.. AU - Bradshaw, T. J.. AU - Spadora, A. C.. AU - Dalton, H. P.. PY - 1987/1/1. Y1 - 1987/1/1. UR - http://www.scopus.com/inward/record.url?scp=0023111265&partnerID=8YFLogxK. UR - http://www.scopus.com/inward/citedby.url?scp=0023111265&partnerID=8YFLogxK. U2 - 10.1017/S0195941700066935. DO - 10.1017/S0195941700066935. M3 - Article. C2 - 3643888. AN - SCOPUS:0023111265. VL - 8. SP - 15. EP - 23. JO - Infection Control and Hospital Epidemiology. JF - Infection Control and Hospital Epidemiology. SN - 0899-823X. IS - 1. ER - ...
A surgical Site Infection occurs at the site of a surgical incision. Germs can get into the incision area, and cause an infection. It can develop within 30 days of an operation, or sometimes even up to one year if an implant (such as a knee or hip joint implant) is used. Infections can be minor, or occasionally they can increase complications that result in a longer length of stay in the hospital, or an increased readmission rate for patients. Post-operative SSIs are the most common health care-associated infections in surgical patients ...
Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterium that is often acquired in the hospital setting and is of increasing burden, particularly among vulnerable patients such as those with compromised immune systems or those who have invasive procedures performed such as surgery. It represents not only a patient safety issue due to its increasing antibiotic-resistance, but a public health concern with approximately 19,000 deaths occurring per year from infection. Furthermore, it is a financial problem for the healthcare field as well due to the estimated $3 billion in excess costs it accounts for in healthcare spending. My research looked to explore what the current prevention and treatment methods are for those infected with MRSA, with an emphasis on nosocomial acquisition. Specifically, the focus was on what particular guidelines are in place for those methods, as well as to examine potential policy recommendations. A literature review of current research and healthcare practices ...
Outbreaks of multidrug-resistant bacteria present a frequent threat to vulnerable patient populations in hospitals around the world. Intensive care unit (ICU) patients are particularly susceptible to nosocomial infections due to indwelling devices such as intravascular catheters, drains, and intratracheal tubes for mechanical ventilation. The increased vulnerability of infected ICU patients demonstrates the importance of effective outbreak management protocols to be in place. Understanding the transmission of pathogens via genotyping methods is an important tool for outbreak management. Recently, whole-genome sequencing (WGS) of pathogens has become more accessible and affordable as a tool for genotyping. Analysis of the entire pathogen genome via WGS could provide unprecedented resolution in discriminating even highly related lineages of bacteria and revolutionize outbreak analysis in hospitals. Nevertheless, clinicians have long been hesitant to implement WGS in outbreak analyses due to the ...